******************************************************************************** MEME - Motif discovery tool ******************************************************************************** MEME version 5.3.3 (Release date: Sun Feb 7 15:39:52 2021 -0800) For further information on how to interpret these results please access https://meme-suite.org/meme. To get a copy of the MEME Suite software please access https://meme-suite.org. ******************************************************************************** ******************************************************************************** REFERENCE ******************************************************************************** If you use this program in your research, please cite: Timothy L. Bailey and Charles Elkan, "Fitting a mixture model by expectation maximization to discover motifs in biopolymers", Proceedings of the Second International Conference on Intelligent Systems for Molecular Biology, pp. 28-36, AAAI Press, Menlo Park, California, 1994. ******************************************************************************** ******************************************************************************** TRAINING SET ******************************************************************************** PRIMARY SEQUENCES= ../result/final_prediction/worm/fasta/RankLinear2.0_40/xbp-1.fasta CONTROL SEQUENCES= --none-- ALPHABET= ACGT Sequence name Weight Length Sequence name Weight Length ------------- ------ ------ ------------- ------ ------ chrII:7352677-7352757 1.0000 80 chrV:9860482-9860562 1.0000 80 chrIV:1973551-1973631 1.0000 80 chrX:6836263-6836343 1.0000 80 chrX:4524972-4525052 1.0000 80 chrI:14662959-14663039 1.0000 80 chrII:12237693-12237773 1.0000 80 chrII:9624263-9624343 1.0000 80 chrV:1570115-1570195 1.0000 80 chrV:20421688-20421768 1.0000 80 chrIII:3469819-3469899 1.0000 80 chrX:4520115-4520195 1.0000 80 chrV:6095991-6096071 1.0000 80 chrIII:7296315-7296395 1.0000 80 chrX:12725133-12725213 1.0000 80 chrII:8811173-8811253 1.0000 80 chrX:10656772-10656852 1.0000 80 chrI:4302373-4302453 1.0000 80 chrIV:5582895-5582975 1.0000 80 chrIII:11378580-11378660 1.0000 80 chrX:4516944-4517024 1.0000 80 chrV:6930325-6930405 1.0000 80 chrX:4522574-4522654 1.0000 80 chrI:14358435-14358515 1.0000 80 chrX:12861132-12861212 1.0000 80 chrIV:11125367-11125447 1.0000 80 chrIII:9571015-9571095 1.0000 80 chrX:6093047-6093127 1.0000 80 chrIII:647350-647430 1.0000 80 chrX:15083961-15084041 1.0000 80 chrV:8026523-8026603 1.0000 80 chrI:12572472-12572552 1.0000 80 chrIII:4367752-4367832 1.0000 80 chrIII:4998411-4998491 1.0000 80 chrIII:11935411-11935491 1.0000 80 chrX:7194044-7194124 1.0000 80 chrIII:3470856-3470936 1.0000 80 chrII:372387-372467 1.0000 80 chrIV:14083120-14083200 1.0000 80 chrIV:15028999-15029079 1.0000 80 chrII:12224185-12224265 1.0000 80 chrV:12560516-12560596 1.0000 80 chrIII:12009881-12009961 1.0000 80 chrIII:6402445-6402525 1.0000 80 chrII:7356958-7357038 1.0000 80 chrX:17216410-17216490 1.0000 80 chrII:8566184-8566264 1.0000 80 chrX:7100425-7100505 1.0000 80 chrIV:4686602-4686682 1.0000 80 chrII:12953528-12953608 1.0000 80 chrI:10683120-10683200 1.0000 80 chrIV:8826769-8826849 1.0000 80 chrV:8302665-8302745 1.0000 80 chrV:20493708-20493788 1.0000 80 chrII:5429850-5429930 1.0000 80 chrI:14946810-14946890 1.0000 80 chrV:12409179-12409259 1.0000 80 chrIV:17288072-17288152 1.0000 80 chrI:8529522-8529602 1.0000 80 chrIII:13383328-13383408 1.0000 80 chrX:4219693-4219773 1.0000 80 chrX:7067703-7067783 1.0000 80 chrI:5420441-5420521 1.0000 80 chrV:20269947-20270027 1.0000 80 chrIV:1056625-1056705 1.0000 80 chrIII:11774659-11774739 1.0000 80 chrII:8661712-8661792 1.0000 80 chrX:6052911-6052991 1.0000 80 chrIII:6625449-6625529 1.0000 80 chrV:9729912-9729992 1.0000 80 chrIV:11142601-11142681 1.0000 80 chrX:12860922-12861002 1.0000 80 chrIV:11112066-11112146 1.0000 80 chrV:8652331-8652411 1.0000 80 chrX:16401081-16401161 1.0000 80 chrI:13807424-13807504 1.0000 80 chrI:4792621-4792701 1.0000 80 chrI:5550565-5550645 1.0000 80 chrX:7066090-7066170 1.0000 80 chrIV:11298707-11298787 1.0000 80 chrIII:8133469-8133549 1.0000 80 chrIII:8405595-8405675 1.0000 80 chrX:6204994-6205074 1.0000 80 chrII:9759575-9759655 1.0000 80 chrIII:3701762-3701842 1.0000 80 chrI:6949429-6949509 1.0000 80 chrI:6038169-6038249 1.0000 80 chrII:7090306-7090386 1.0000 80 chrI:5937068-5937148 1.0000 80 chrIII:12711380-12711460 1.0000 80 chrV:10873347-10873427 1.0000 80 chrIV:9260508-9260588 1.0000 80 chrV:17870724-17870804 1.0000 80 chrIV:11026790-11026870 1.0000 80 chrIII:12345119-12345199 1.0000 80 chrIII:4275825-4275905 1.0000 80 chrI:12974146-12974226 1.0000 80 chrV:9856613-9856693 1.0000 80 chrX:6934608-6934688 1.0000 80 chrIV:9525119-9525199 1.0000 80 chrI:7926427-7926507 1.0000 80 chrIV:8975084-8975164 1.0000 80 chrX:6020206-6020286 1.0000 80 chrV:11503495-11503575 1.0000 80 chrI:12106427-12106507 1.0000 80 chrI:7747574-7747654 1.0000 80 chrI:2045091-2045171 1.0000 80 chrI:7129604-7129684 1.0000 80 chrIV:2896157-2896237 1.0000 80 chrV:5939667-5939747 1.0000 80 chrII:12931583-12931663 1.0000 80 chrI:13840071-13840151 1.0000 80 chrX:3772597-3772677 1.0000 80 chrIV:16034487-16034567 1.0000 80 chrIV:8113290-8113370 1.0000 80 chrX:17002159-17002239 1.0000 80 chrV:20415573-20415653 1.0000 80 chrIII:6009116-6009196 1.0000 80 chrI:13161984-13162064 1.0000 80 chrIII:13152812-13152892 1.0000 80 chrII:161322-161402 1.0000 80 chrII:3616769-3616849 1.0000 80 chrV:11733652-11733732 1.0000 80 chrIV:9403872-9403952 1.0000 80 chrV:10661636-10661716 1.0000 80 chrIII:3705132-3705212 1.0000 80 chrIV:17285446-17285526 1.0000 80 chrI:14570432-14570512 1.0000 80 chrIV:8869789-8869869 1.0000 80 chrV:19190137-19190217 1.0000 80 chrX:6505174-6505254 1.0000 80 chrI:1895095-1895175 1.0000 80 chrI:4805450-4805530 1.0000 80 chrI:814038-814118 1.0000 80 chrV:12184461-12184541 1.0000 80 chrI:14839813-14839893 1.0000 80 chrII:7864374-7864454 1.0000 80 chrII:10300522-10300602 1.0000 80 chrV:10002937-10003017 1.0000 80 chrV:6043427-6043507 1.0000 80 chrII:7874138-7874218 1.0000 80 chrIV:12605528-12605608 1.0000 80 chrIII:10903331-10903411 1.0000 80 chrX:5298302-5298382 1.0000 80 chrX:4529052-4529132 1.0000 80 chrX:11415028-11415108 1.0000 80 chrI:10591702-10591782 1.0000 80 chrIV:2890724-2890804 1.0000 80 chrIV:1953277-1953357 1.0000 80 chrV:19949505-19949585 1.0000 80 chrX:14513628-14513708 1.0000 80 chrII:1402321-1402401 1.0000 80 chrII:13477367-13477447 1.0000 80 chrX:4818428-4818508 1.0000 80 chrII:4828195-4828275 1.0000 80 chrIV:11521102-11521182 1.0000 80 chrV:4063712-4063792 1.0000 80 chrIV:9534495-9534575 1.0000 80 chrI:2668664-2668744 1.0000 80 chrI:1808017-1808097 1.0000 80 chrI:9141742-9141822 1.0000 80 chrII:13083908-13083988 1.0000 80 chrI:4381852-4381932 1.0000 80 chrIV:132271-132351 1.0000 80 chrX:6729728-6729808 1.0000 80 chrI:3600840-3600920 1.0000 80 chrII:9242971-9243051 1.0000 80 chrX:6240436-6240516 1.0000 80 chrIV:5160329-5160409 1.0000 80 chrIV:2776112-2776192 1.0000 80 chrIV:9386182-9386262 1.0000 80 chrI:10970244-10970324 1.0000 80 chrX:4462560-4462640 1.0000 80 chrX:4588082-4588162 1.0000 80 chrIII:5499108-5499188 1.0000 80 chrII:6321169-6321249 1.0000 80 chrI:14953181-14953261 1.0000 80 chrIII:4332694-4332774 1.0000 80 chrIV:11111381-11111461 1.0000 80 chrII:4762702-4762782 1.0000 80 chrI:12183243-12183323 1.0000 80 chrI:323626-323706 1.0000 80 chrIII:3855017-3855097 1.0000 80 chrI:14710999-14711079 1.0000 80 chrIV:4024782-4024862 1.0000 80 chrIV:2349074-2349154 1.0000 80 chrIV:5561537-5561617 1.0000 80 chrI:663630-663710 1.0000 80 chrV:5204322-5204402 1.0000 80 chrIV:992163-992243 1.0000 80 chrX:7076672-7076752 1.0000 80 chrI:8254956-8255036 1.0000 80 chrV:10757182-10757262 1.0000 80 chrI:3070214-3070294 1.0000 80 chrX:5486106-5486186 1.0000 80 chrV:18086929-18087009 1.0000 80 chrI:13859224-13859304 1.0000 80 chrIV:10367977-10368057 1.0000 80 chrIV:7512991-7513071 1.0000 80 chrIII:1905771-1905851 1.0000 80 chrIII:4456736-4456816 1.0000 80 chrI:6358548-6358628 1.0000 80 chrIII:1037333-1037413 1.0000 80 chrI:6626892-6626972 1.0000 80 chrV:6110689-6110769 1.0000 80 chrIII:8631015-8631095 1.0000 80 chrV:6427550-6427630 1.0000 80 chrI:7057000-7057080 1.0000 80 chrIII:8029643-8029723 1.0000 80 chrIII:8432308-8432388 1.0000 80 chrIV:7982204-7982284 1.0000 80 chrV:6098841-6098921 1.0000 80 chrIV:1054887-1054967 1.0000 80 chrI:6850029-6850109 1.0000 80 chrIV:4720708-4720788 1.0000 80 chrIV:3519551-3519631 1.0000 80 chrIV:4184941-4185021 1.0000 80 chrI:9848137-9848217 1.0000 80 chrX:4260459-4260539 1.0000 80 chrIII:3650854-3650934 1.0000 80 chrX:7233895-7233975 1.0000 80 chrII:11676099-11676179 1.0000 80 chrIV:11125569-11125649 1.0000 80 chrIII:634719-634799 1.0000 80 chrV:9128747-9128827 1.0000 80 chrX:12990903-12990983 1.0000 80 chrII:8429110-8429190 1.0000 80 chrIV:4357433-4357513 1.0000 80 chrV:11327137-11327217 1.0000 80 chrV:15578504-15578584 1.0000 80 chrII:386118-386198 1.0000 80 chrI:3019639-3019719 1.0000 80 chrIV:12029970-12030050 1.0000 80 chrI:4671878-4671958 1.0000 80 chrIV:14070352-14070432 1.0000 80 chrIV:3694812-3694892 1.0000 80 chrIII:6489080-6489160 1.0000 80 chrIV:9335984-9336064 1.0000 80 chrIV:813520-813600 1.0000 80 chrII:9669113-9669193 1.0000 80 chrIII:2487250-2487330 1.0000 80 chrI:7069265-7069345 1.0000 80 chrIII:4113795-4113875 1.0000 80 chrI:3741265-3741345 1.0000 80 chrV:6225611-6225691 1.0000 80 chrX:7306593-7306673 1.0000 80 chrIII:12152332-12152412 1.0000 80 chrIV:12209165-12209245 1.0000 80 chrV:1196153-1196233 1.0000 80 chrX:4957469-4957549 1.0000 80 ******************************************************************************** ******************************************************************************** COMMAND LINE SUMMARY ******************************************************************************** This information can also be useful in the event you wish to report a problem with the MEME software. command: meme -oc ../result/final_prediction/worm/inference_raw/MEME/RankLinear2.0_40_xbp-1/ -dna -nmotifs 5 -w 8 -maxsize 250000 -nostatus ../result/final_prediction/worm/fasta/RankLinear2.0_40/xbp-1.fasta model: mod= zoops nmotifs= 5 evt= inf objective function: em= E-value of product of p-values starts= E-value of product of p-values strands: + width: minw= 8 maxw= 8 nsites: minsites= 2 maxsites= 250 wnsites= 0.8 theta: spmap= uni spfuzz= 0.5 em: prior= dirichlet b= 0.01 maxiter= 50 distance= 1e-05 trim: wg= 11 ws= 1 endgaps= yes data: n= 20000 N= 250 sample: seed= 0 hsfrac= 0 searchsize= 20000 norand= no csites= 1000 Letter frequencies in dataset: A 0.273 C 0.224 G 0.222 T 0.28 Background letter frequencies (from file dataset with add-one prior applied): A 0.273 C 0.224 G 0.222 T 0.28 Background model order: 0 ******************************************************************************** ******************************************************************************** MOTIF GCGCACTT MEME-1 width = 8 sites = 53 llr = 447 E-value = 2.5e-022 ******************************************************************************** -------------------------------------------------------------------------------- Motif GCGCACTT MEME-1 Description -------------------------------------------------------------------------------- Simplified A ::::8::: pos.-specific C 1a18:7:1 probability G 9:912::1 matrix T :::1:3a9 bits 2.2 * 2.0 * 1.7 ** * 1.5 *** * Relative 1.3 *** ** Entropy 1.1 ******** (12.2 bits) 0.9 ******** 0.7 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel GCGCACTT consensus GT sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GCGCACTT MEME-1 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chrI:3741265-3741345 34 1.19e-05 GTGCGGTGGA GCGCACTT GCCACACATT chrIV:14070352-14070432 28 1.19e-05 TGTCAATGGA GCGCACTT ACAGCCAAAA chrIV:4357433-4357513 60 1.19e-05 gtgcgatgga gcgcactt gccaaatttt chrIII:634719-634799 50 1.19e-05 CTTCTCGTTT GCGCACTT TCGGTGCGTT chrV:18086929-18087009 56 1.19e-05 gtccaatgga gcgcactt gcattatttt chrI:663630-663710 73 1.19e-05 TGACGGTGGA GCGCACTT chrX:4588082-4588162 58 1.19e-05 CCGTTACTTT GCGCACTT GTTGACGTTC chrI:10970244-10970324 43 1.19e-05 AATTTTGTTG GCGCACTT CTCGCGCATG chrIV:9386182-9386262 48 1.19e-05 GTGCAACGGA GCGCACTT GCACGAATCA chrV:17870724-17870804 37 1.19e-05 TCTCAATGGG GCGCACTT GCACCACACA chrI:10683120-10683200 52 1.19e-05 TTTCCATGGA GCGCACTT GCACATTTCA chrX:7100425-7100505 37 1.19e-05 TCTCAATAGA GCGCACTT GTACAGAGAC chrX:6093047-6093127 72 1.19e-05 TATCAATGGG GCGCACTT A chrII:9624263-9624343 56 1.19e-05 AAGCGGTGGA GCGCACTT GCATTTTTTC chrI:12183243-12183323 19 2.15e-05 AATAACGCTA GCGCGCTT TGTTTATCGT chrIV:5160329-5160409 58 2.15e-05 TGTCAATGGA GCGCGCTT ACGCAGCTAA chrV:11733652-11733732 36 2.15e-05 TGTCATTGGA GCGCGCTT TCCCCAACGG chrII:11676099-11676179 69 3.63e-05 GCGGTTGTTG GCGCATTT CACG chrIII:1037333-1037413 49 3.63e-05 AATTTCCTTG GCGCATTT CTCGACCAAA chrIV:2349074-2349154 44 3.63e-05 GACTTTGCTG GCGCATTT CTCGTGCGTT chrII:4828195-4828275 57 3.63e-05 TTGAACACCC GCGCATTT TTGTGTCTGC chrII:13477367-13477447 38 3.63e-05 TTCCGGTGGA GCGCATTT ACTGAGTCCG chrIV:2896157-2896237 67 3.63e-05 actacacagc gcgcattt taattg chrV:1196153-1196233 39 4.81e-05 CAAACACATT GCGGACTT TGTGCGGAAT chrIII:2487250-2487330 18 4.81e-05 ACGCGCAATT GCGGACTT CTAATCCCGC chrX:3772597-3772677 23 4.81e-05 ACGCACAATT GCGGACTT CCACGCAGGC chrII:5429850-5429930 52 4.81e-05 ACACCGCGCT GCGGACTT TGCACGGAAT chrX:4516944-4517024 49 4.81e-05 AGGCAAAATT GCGGACTT AGGAGTGTTG chrIII:12152332-12152412 23 6.96e-05 TATCAACAGG GCGCGTTT GCACTTTTCA chrI:6358548-6358628 50 6.96e-05 AGTTGTGTTA GCGCACTC TCCGTGCACT chrX:4462560-4462640 38 6.96e-05 TGTCAATAGA GCGCGTTT GCATTTTTTA chrI:4805450-4805530 16 6.96e-05 GTCCATCGGA GCGCGTTT GCTCACACAG chrII:386118-386198 56 9.38e-05 TGTTGCGCTT GCGTACTT TTATTTTTCT chrX:12990903-12990983 2 9.38e-05 C GCGTACTT TGTTAACGGT chrX:6934608-6934688 6 9.38e-05 GCAGA GCGTACTT TCGTTTTCCT chrIV:992163-992243 34 1.06e-04 ACGCGCTCCA CCGcactt tcttttttat chrII:8661712-8661792 15 1.06e-04 TGACGCCCTA CCGCACTT TCTCTTTGTG chrI:9848137-9848217 7 1.18e-04 AACTCT GCCCACTT TTGAACCAAT chrI:14570432-14570512 47 1.18e-04 GATTGGCTCC GCCCACTT TAATCCTGAC chrV:11503495-11503575 13 1.18e-04 TAGAAGTTAC GCCCACTT TTGCACCAAT chrIV:3694812-3694892 23 1.50e-04 AAAAATGCAA GCGCGCTC TACCGCACAC chrV:12184461-12184541 64 1.50e-04 GTCGTAAGTG GCGGATTT TCAAATAAA chrIII:13152812-13152892 68 1.50e-04 CGCGAAGCAA GCGCGCTC CACTG chrI:14358435-14358515 72 1.64e-04 acggtaaaat gcacactt t chrV:6095991-6096071 46 1.64e-04 GATGGTGTTT GCACACTT TTCACCACAA chrIV:1054887-1054967 49 1.96e-04 GGTAAACAGG GCGCGCTG CGGGATTTTG chrIII:8432308-8432388 37 1.96e-04 GATAAAGAGA GCGCGCTG TCGTTACTTC chrI:13840071-13840151 47 1.96e-04 CACACCTGAC GCGCATTC ACTTTTGTAG chrV:9729912-9729992 71 1.96e-04 CGTCTATAGA GCGTGCTT GC chrV:12560516-12560596 47 2.06e-04 TTATTACGCA CCGCGCTT TGTTTATCGT chrIV:11521102-11521182 47 2.36e-04 AATGCCACGT GCGCATTG TTTACCGTAA chrIV:11142601-11142681 41 2.36e-04 TGTGGTGTTT GCGTATTT TTGGGTCAAA chrIII:3855017-3855097 22 2.51e-04 ACACAAAACA CCGCATTT TACGACATTT -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GCGCACTT MEME-1 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chrI:3741265-3741345 1.2e-05 33_[+1]_39 chrIV:14070352-14070432 1.2e-05 27_[+1]_45 chrIV:4357433-4357513 1.2e-05 59_[+1]_13 chrIII:634719-634799 1.2e-05 49_[+1]_23 chrV:18086929-18087009 1.2e-05 55_[+1]_17 chrI:663630-663710 1.2e-05 72_[+1] chrX:4588082-4588162 1.2e-05 57_[+1]_15 chrI:10970244-10970324 1.2e-05 42_[+1]_30 chrIV:9386182-9386262 1.2e-05 47_[+1]_25 chrV:17870724-17870804 1.2e-05 36_[+1]_36 chrI:10683120-10683200 1.2e-05 51_[+1]_21 chrX:7100425-7100505 1.2e-05 36_[+1]_36 chrX:6093047-6093127 1.2e-05 71_[+1]_1 chrII:9624263-9624343 1.2e-05 55_[+1]_17 chrI:12183243-12183323 2.1e-05 18_[+1]_54 chrIV:5160329-5160409 2.1e-05 57_[+1]_15 chrV:11733652-11733732 2.1e-05 35_[+1]_37 chrII:11676099-11676179 3.6e-05 68_[+1]_4 chrIII:1037333-1037413 3.6e-05 48_[+1]_24 chrIV:2349074-2349154 3.6e-05 43_[+1]_29 chrII:4828195-4828275 3.6e-05 56_[+1]_16 chrII:13477367-13477447 3.6e-05 37_[+1]_35 chrIV:2896157-2896237 3.6e-05 66_[+1]_6 chrV:1196153-1196233 4.8e-05 38_[+1]_34 chrIII:2487250-2487330 4.8e-05 17_[+1]_55 chrX:3772597-3772677 4.8e-05 22_[+1]_50 chrII:5429850-5429930 4.8e-05 51_[+1]_21 chrX:4516944-4517024 4.8e-05 48_[+1]_24 chrIII:12152332-12152412 7e-05 22_[+1]_50 chrI:6358548-6358628 7e-05 49_[+1]_23 chrX:4462560-4462640 7e-05 37_[+1]_35 chrI:4805450-4805530 7e-05 15_[+1]_57 chrII:386118-386198 9.4e-05 55_[+1]_17 chrX:12990903-12990983 9.4e-05 1_[+1]_71 chrX:6934608-6934688 9.4e-05 5_[+1]_67 chrIV:992163-992243 0.00011 33_[+1]_39 chrII:8661712-8661792 0.00011 14_[+1]_58 chrI:9848137-9848217 0.00012 6_[+1]_66 chrI:14570432-14570512 0.00012 46_[+1]_26 chrV:11503495-11503575 0.00012 12_[+1]_60 chrIV:3694812-3694892 0.00015 22_[+1]_50 chrV:12184461-12184541 0.00015 63_[+1]_9 chrIII:13152812-13152892 0.00015 67_[+1]_5 chrI:14358435-14358515 0.00016 71_[+1]_1 chrV:6095991-6096071 0.00016 45_[+1]_27 chrIV:1054887-1054967 0.0002 48_[+1]_24 chrIII:8432308-8432388 0.0002 36_[+1]_36 chrI:13840071-13840151 0.0002 46_[+1]_26 chrV:9729912-9729992 0.0002 70_[+1]_2 chrV:12560516-12560596 0.00021 46_[+1]_26 chrIV:11521102-11521182 0.00024 46_[+1]_26 chrIV:11142601-11142681 0.00024 40_[+1]_32 chrIII:3855017-3855097 0.00025 21_[+1]_51 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GCGCACTT MEME-1 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF GCGCACTT width=8 seqs=53 chrI:3741265-3741345 ( 34) GCGCACTT 1 chrIV:14070352-14070432 ( 28) GCGCACTT 1 chrIV:4357433-4357513 ( 60) GCGCACTT 1 chrIII:634719-634799 ( 50) GCGCACTT 1 chrV:18086929-18087009 ( 56) GCGCACTT 1 chrI:663630-663710 ( 73) GCGCACTT 1 chrX:4588082-4588162 ( 58) GCGCACTT 1 chrI:10970244-10970324 ( 43) GCGCACTT 1 chrIV:9386182-9386262 ( 48) GCGCACTT 1 chrV:17870724-17870804 ( 37) GCGCACTT 1 chrI:10683120-10683200 ( 52) GCGCACTT 1 chrX:7100425-7100505 ( 37) GCGCACTT 1 chrX:6093047-6093127 ( 72) GCGCACTT 1 chrII:9624263-9624343 ( 56) GCGCACTT 1 chrI:12183243-12183323 ( 19) GCGCGCTT 1 chrIV:5160329-5160409 ( 58) GCGCGCTT 1 chrV:11733652-11733732 ( 36) GCGCGCTT 1 chrII:11676099-11676179 ( 69) GCGCATTT 1 chrIII:1037333-1037413 ( 49) GCGCATTT 1 chrIV:2349074-2349154 ( 44) GCGCATTT 1 chrII:4828195-4828275 ( 57) GCGCATTT 1 chrII:13477367-13477447 ( 38) GCGCATTT 1 chrIV:2896157-2896237 ( 67) GCGCATTT 1 chrV:1196153-1196233 ( 39) GCGGACTT 1 chrIII:2487250-2487330 ( 18) GCGGACTT 1 chrX:3772597-3772677 ( 23) GCGGACTT 1 chrII:5429850-5429930 ( 52) GCGGACTT 1 chrX:4516944-4517024 ( 49) GCGGACTT 1 chrIII:12152332-12152412 ( 23) GCGCGTTT 1 chrI:6358548-6358628 ( 50) GCGCACTC 1 chrX:4462560-4462640 ( 38) GCGCGTTT 1 chrI:4805450-4805530 ( 16) GCGCGTTT 1 chrII:386118-386198 ( 56) GCGTACTT 1 chrX:12990903-12990983 ( 2) GCGTACTT 1 chrX:6934608-6934688 ( 6) GCGTACTT 1 chrIV:992163-992243 ( 34) CCGCACTT 1 chrII:8661712-8661792 ( 15) CCGCACTT 1 chrI:9848137-9848217 ( 7) GCCCACTT 1 chrI:14570432-14570512 ( 47) GCCCACTT 1 chrV:11503495-11503575 ( 13) GCCCACTT 1 chrIV:3694812-3694892 ( 23) GCGCGCTC 1 chrV:12184461-12184541 ( 64) GCGGATTT 1 chrIII:13152812-13152892 ( 68) GCGCGCTC 1 chrI:14358435-14358515 ( 72) GCACACTT 1 chrV:6095991-6096071 ( 46) GCACACTT 1 chrIV:1054887-1054967 ( 49) GCGCGCTG 1 chrIII:8432308-8432388 ( 37) GCGCGCTG 1 chrI:13840071-13840151 ( 47) GCGCATTC 1 chrV:9729912-9729992 ( 71) GCGTGCTT 1 chrV:12560516-12560596 ( 47) CCGCGCTT 1 chrIV:11521102-11521182 ( 47) GCGCATTG 1 chrIV:11142601-11142681 ( 41) GCGTATTT 1 chrIII:3855017-3855097 ( 22) CCGCATTT 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GCGCACTT MEME-1 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 9.60532 E= 2.5e-022 -1237 -157 206 -1237 -1237 216 -1237 -1237 -285 -199 203 -1237 -1237 182 -97 -157 150 -1237 3 -1237 -1237 171 -1237 -9 -1237 -1237 -1237 183 -1237 -157 -197 163 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GCGCACTT MEME-1 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 53 E= 2.5e-022 0.000000 0.075472 0.924528 0.000000 0.000000 1.000000 0.000000 0.000000 0.037736 0.056604 0.905660 0.000000 0.000000 0.792453 0.113208 0.094340 0.773585 0.000000 0.226415 0.000000 0.000000 0.735849 0.000000 0.264151 0.000000 0.000000 0.000000 1.000000 0.000000 0.075472 0.056604 0.867925 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GCGCACTT MEME-1 regular expression -------------------------------------------------------------------------------- GCGC[AG][CT]TT -------------------------------------------------------------------------------- Time 9.44 secs. ******************************************************************************** ******************************************************************************** MOTIF KHSACGTS MEME-2 width = 8 sites = 70 llr = 527 E-value = 1.2e-016 ******************************************************************************** -------------------------------------------------------------------------------- Motif KHSACGTS MEME-2 Description -------------------------------------------------------------------------------- Simplified A 24:a:::: pos.-specific C 235:a::6 probability G 4:5::a:4 matrix T 33::::a: bits 2.2 ** 2.0 *** 1.7 **** 1.5 **** Relative 1.3 **** Entropy 1.1 ****** (10.9 bits) 0.9 ****** 0.7 ****** 0.4 ******* 0.2 ******** 0.0 -------- Multilevel GACACGTC consensus TTG G sequence C -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif KHSACGTS MEME-2 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chrIII:4456736-4456816 50 9.48e-06 TGTGTGGGGC GCCACGtc ttctccctct chrII:4762702-4762782 7 9.48e-06 CCCATC GCCACGTC ATCCTAATCA chrIII:10903331-10903411 50 9.48e-06 TTTAGTATGT GCCACGTC TCTTTTAAGC chrII:10300522-10300602 32 9.48e-06 CGTGACGTCA GCCACGTC ACATTCCTTC chrIV:11112066-11112146 27 9.48e-06 TCATCCATTT GCCACGTC AGTTGTCGTG chrIII:6402445-6402525 25 9.48e-06 TAATATCTTT GCCACGTC ACACAAGATC chrIII:12009881-12009961 28 9.48e-06 gtgtgtgtgt gCCACGTC ATCATTTTCT chrIII:647350-647430 3 9.48e-06 AC GCCACGTC ACCACTCTGT chrV:6930325-6930405 8 9.48e-06 ACCTTAC GCCACGTC ACACACACCT chrII:8429110-8429190 62 2.10e-05 CAGAAAACCT GACACGTC ATCTTATTTA chrIV:17285446-17285526 29 2.10e-05 GATGAGAAGC GACACGTC ACTCATGACG chrIII:3701762-3701842 32 2.10e-05 GTGCAGTATT GACACGTC AGCATACGCG chrIII:11774659-11774739 3 2.10e-05 AC GACACGTC ACGTGCACCG chrV:8302665-8302745 12 2.10e-05 AATTCACAGA GACACGTC ACAAAAATGA chrI:12572472-12572552 29 4.23e-05 CGTGGCTTAC GCGACGTC GATTTGCCGG chrV:10002937-10003017 58 5.38e-05 ATTCTACAAA GAGACGTC ATCTTTTTCA chrIV:2776112-2776192 64 7.49e-05 GAAGAGCTGT GTGACGTC GCTGGAAAC chrI:2668664-2668744 9 7.49e-05 ACTCTGGA GTGACGTC GACTTGCACT chrI:4792621-4792701 64 7.49e-05 GTGATCTAGT GTGACGTC ATATGGGGT chrV:8652331-8652411 25 7.49e-05 TGTCTGAAAG GTGACGTC GTCTAAGACG chrII:8661712-8661792 30 7.49e-05 CTTTCTCTTT GTGACGTC ACTATTTTCC chrIV:9534495-9534575 54 1.19e-04 GGACGACGGG GTCACGTG ATGGAAGAAA chrX:12725133-12725213 50 1.19e-04 ATCTCCCCAC TCCACGTC TTCTACTAGT chrIV:11125569-11125649 73 1.55e-04 AGTCGATTCG TACACGTC chrII:12931583-12931663 5 1.55e-04 TAAG TACACGTC GCATACCGCC chrX:16401081-16401161 44 1.55e-04 GCATTGTTTG TACACGTC ACACTCACAC chrI:14946810-14946890 34 1.55e-04 ATCGACAAGT GAGACGTG GTGGCCGAGG chrII:5429850-5429930 22 1.55e-04 TTTAGCGAGT TACACGTC GAAAGTACGC chrX:4522574-4522654 30 1.55e-04 AAACGAAGGC GAGACGTG AAAAGAGTGC chrI:8254956-8255036 21 2.05e-04 AGAAGACTAT CACACGTC GAATTAATCG chrIV:16034487-16034567 28 2.05e-04 CGATAAGCTG GTGACGTG CTACGTCGCT chrI:7129604-7129684 24 2.05e-04 CGGTGTTTGT GTGACGTG GCAATTCATC chrI:7926427-7926507 43 2.05e-04 TGCAAACACT TTCACGTC AAATTGCGGA chrII:372387-372467 51 2.05e-04 CGCTGATTGG TCGACGTC ATAGACGCGT chrV:20421688-20421768 36 2.05e-04 AATGCTCAAT GTGACGTG GATTAGCGGG chrII:9624263-9624343 26 2.05e-04 CACGTTTATG CACACGTC AGTTAAACGG chrV:15578504-15578584 10 2.41e-04 AGAAATTTG CCGACGTC ACTCCAATGT chrII:7864374-7864454 23 2.41e-04 TGTGTGCAAT CTCACGTC ACGGTGTTTG chrX:5486106-5486186 57 2.91e-04 AATAGGATGG TTGACGTC TTTTCCGTGT chrX:4529052-4529132 6 2.91e-04 CAACC TCCACGTG ATTCTCTTGT chrX:5298302-5298382 53 2.91e-04 TAACCGCGCG TTGACGTC ATTTGTGTAA chrI:5550565-5550645 10 2.91e-04 TTTTTATAA ACCACGTC GAACTGCCCT chrV:20493708-20493788 59 2.91e-04 AACACTGTTG TCCACGTG TAGAACTTGT chrIV:7982204-7982284 37 3.41e-04 TAATCGAAAT TACACGTG TGTGGCTGGC chrV:10873347-10873427 41 3.41e-04 TGGGTGGACG TACACGTG GACAAAAGTA chrIII:8133469-8133549 44 3.41e-04 CTCAGTTTAG TACACGTG TATCAGGCAT chrI:8529522-8529602 29 3.41e-04 AACGTCAGAG TACACGTG GCAAAAATCG chrV:8026523-8026603 38 3.41e-04 ATCTCTGTGT CCCACGTG TAAGAATACG chrIV:1973551-1973631 33 3.41e-04 GTTTGCACTG CTGACGTC GATTTGAGCC chrIV:9386182-9386262 62 4.05e-04 ACTTGCACGA ATCACGTC TTCTTTAAAT chrV:20415573-20415653 64 4.05e-04 AGAGTGGAAG ACGACGTC GACTAAACG chrIV:8826769-8826849 62 4.05e-04 GCCGTGTTGG TCGACGTG TCTCTCGAAA chrIV:15028999-15029079 3 4.05e-04 AT CACACGTG AATTAGTCGT chrX:4520115-4520195 33 4.05e-04 TTCTCACAAG TCGACGTG TCACTATCGA chrI:1808017-1808097 4 4.55e-04 AAG AAGACGTC ACGTAGGCTA chrI:4805450-4805530 38 4.55e-04 ACACAGTAGT CCGACGTG GTGTAGTCCT chrIII:8405595-8405675 5 4.55e-04 TAAA AAGACGTC GAATAATTCG chrIV:4024782-4024862 16 5.07e-04 GAAAATCAAA ATGACGTC ATCTTACTGT chrX:17216410-17216490 49 5.07e-04 GTAGATCCTC ACCACGTG GAACTCACTC chrV:6095991-6096071 29 5.07e-04 AATCCGTGAC TTGACGTG ATGGTGTTTG chrI:4671878-4671958 60 5.33e-04 CAAGAAGGTG CTGACGTG GCACATATTT chrI:2045091-2045171 61 5.33e-04 TTTGCGCAGT AACACGTG GCCTACATAA chrX:6020206-6020286 26 5.33e-04 TAAAACATCG AACACGTG GAAGGACAGC chrV:20269947-20270027 68 5.33e-04 TACGCAGTGG CTGACGTG TATTT chrIV:17288072-17288152 34 5.33e-04 TGGCGAAACG CTGACGTG TTATAACACC chrII:8566184-8566264 30 5.33e-04 ATTTCAGGCG CTGACGTG TGCTAAAAAT chrX:4524972-4525052 62 5.33e-04 ACTGTCTATG CTGACGTG AACTAGTAGA chrX:6836263-6836343 32 5.33e-04 AGTGGGAGAG AACACGTG CAAAGGGGAG chrII:161322-161402 13 5.73e-04 CATAGAGAAT AAGACGTG GAGATTGACA chrII:7352677-7352757 44 5.87e-04 CTTATCGGAG ATGACGTG TATTAGTGCT -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif KHSACGTS MEME-2 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chrIII:4456736-4456816 9.5e-06 49_[+2]_23 chrII:4762702-4762782 9.5e-06 6_[+2]_66 chrIII:10903331-10903411 9.5e-06 49_[+2]_23 chrII:10300522-10300602 9.5e-06 31_[+2]_41 chrIV:11112066-11112146 9.5e-06 26_[+2]_46 chrIII:6402445-6402525 9.5e-06 24_[+2]_48 chrIII:12009881-12009961 9.5e-06 27_[+2]_45 chrIII:647350-647430 9.5e-06 2_[+2]_70 chrV:6930325-6930405 9.5e-06 7_[+2]_65 chrII:8429110-8429190 2.1e-05 61_[+2]_11 chrIV:17285446-17285526 2.1e-05 28_[+2]_44 chrIII:3701762-3701842 2.1e-05 31_[+2]_41 chrIII:11774659-11774739 2.1e-05 2_[+2]_70 chrV:8302665-8302745 2.1e-05 11_[+2]_61 chrI:12572472-12572552 4.2e-05 28_[+2]_44 chrV:10002937-10003017 5.4e-05 57_[+2]_15 chrIV:2776112-2776192 7.5e-05 63_[+2]_9 chrI:2668664-2668744 7.5e-05 8_[+2]_64 chrI:4792621-4792701 7.5e-05 63_[+2]_9 chrV:8652331-8652411 7.5e-05 24_[+2]_48 chrII:8661712-8661792 7.5e-05 29_[+2]_43 chrIV:9534495-9534575 0.00012 53_[+2]_19 chrX:12725133-12725213 0.00012 49_[+2]_23 chrIV:11125569-11125649 0.00015 72_[+2] chrII:12931583-12931663 0.00015 4_[+2]_68 chrX:16401081-16401161 0.00015 43_[+2]_29 chrI:14946810-14946890 0.00015 33_[+2]_39 chrII:5429850-5429930 0.00015 21_[+2]_51 chrX:4522574-4522654 0.00015 29_[+2]_43 chrI:8254956-8255036 0.00021 20_[+2]_52 chrIV:16034487-16034567 0.00021 27_[+2]_45 chrI:7129604-7129684 0.00021 23_[+2]_49 chrI:7926427-7926507 0.00021 42_[+2]_30 chrII:372387-372467 0.00021 50_[+2]_22 chrV:20421688-20421768 0.00021 35_[+2]_37 chrII:9624263-9624343 0.00021 25_[+2]_47 chrV:15578504-15578584 0.00024 9_[+2]_63 chrII:7864374-7864454 0.00024 22_[+2]_50 chrX:5486106-5486186 0.00029 56_[+2]_16 chrX:4529052-4529132 0.00029 5_[+2]_67 chrX:5298302-5298382 0.00029 52_[+2]_20 chrI:5550565-5550645 0.00029 9_[+2]_63 chrV:20493708-20493788 0.00029 58_[+2]_14 chrIV:7982204-7982284 0.00034 36_[+2]_36 chrV:10873347-10873427 0.00034 40_[+2]_32 chrIII:8133469-8133549 0.00034 43_[+2]_29 chrI:8529522-8529602 0.00034 28_[+2]_44 chrV:8026523-8026603 0.00034 37_[+2]_35 chrIV:1973551-1973631 0.00034 32_[+2]_40 chrIV:9386182-9386262 0.00041 61_[+2]_11 chrV:20415573-20415653 0.00041 63_[+2]_9 chrIV:8826769-8826849 0.00041 61_[+2]_11 chrIV:15028999-15029079 0.00041 2_[+2]_70 chrX:4520115-4520195 0.00041 32_[+2]_40 chrI:1808017-1808097 0.00045 3_[+2]_69 chrI:4805450-4805530 0.00045 37_[+2]_35 chrIII:8405595-8405675 0.00045 4_[+2]_68 chrIV:4024782-4024862 0.00051 15_[+2]_57 chrX:17216410-17216490 0.00051 48_[+2]_24 chrV:6095991-6096071 0.00051 28_[+2]_44 chrI:4671878-4671958 0.00053 59_[+2]_13 chrI:2045091-2045171 0.00053 60_[+2]_12 chrX:6020206-6020286 0.00053 25_[+2]_47 chrV:20269947-20270027 0.00053 67_[+2]_5 chrIV:17288072-17288152 0.00053 33_[+2]_39 chrII:8566184-8566264 0.00053 29_[+2]_43 chrX:4524972-4525052 0.00053 61_[+2]_11 chrX:6836263-6836343 0.00053 31_[+2]_41 chrII:161322-161402 0.00057 12_[+2]_60 chrII:7352677-7352757 0.00059 43_[+2]_29 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif KHSACGTS MEME-2 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF KHSACGTS width=8 seqs=70 chrIII:4456736-4456816 ( 50) GCCACGTC 1 chrII:4762702-4762782 ( 7) GCCACGTC 1 chrIII:10903331-10903411 ( 50) GCCACGTC 1 chrII:10300522-10300602 ( 32) GCCACGTC 1 chrIV:11112066-11112146 ( 27) GCCACGTC 1 chrIII:6402445-6402525 ( 25) GCCACGTC 1 chrIII:12009881-12009961 ( 28) GCCACGTC 1 chrIII:647350-647430 ( 3) GCCACGTC 1 chrV:6930325-6930405 ( 8) GCCACGTC 1 chrII:8429110-8429190 ( 62) GACACGTC 1 chrIV:17285446-17285526 ( 29) GACACGTC 1 chrIII:3701762-3701842 ( 32) GACACGTC 1 chrIII:11774659-11774739 ( 3) GACACGTC 1 chrV:8302665-8302745 ( 12) GACACGTC 1 chrI:12572472-12572552 ( 29) GCGACGTC 1 chrV:10002937-10003017 ( 58) GAGACGTC 1 chrIV:2776112-2776192 ( 64) GTGACGTC 1 chrI:2668664-2668744 ( 9) GTGACGTC 1 chrI:4792621-4792701 ( 64) GTGACGTC 1 chrV:8652331-8652411 ( 25) GTGACGTC 1 chrII:8661712-8661792 ( 30) GTGACGTC 1 chrIV:9534495-9534575 ( 54) GTCACGTG 1 chrX:12725133-12725213 ( 50) TCCACGTC 1 chrIV:11125569-11125649 ( 73) TACACGTC 1 chrII:12931583-12931663 ( 5) TACACGTC 1 chrX:16401081-16401161 ( 44) TACACGTC 1 chrI:14946810-14946890 ( 34) GAGACGTG 1 chrII:5429850-5429930 ( 22) TACACGTC 1 chrX:4522574-4522654 ( 30) GAGACGTG 1 chrI:8254956-8255036 ( 21) CACACGTC 1 chrIV:16034487-16034567 ( 28) GTGACGTG 1 chrI:7129604-7129684 ( 24) GTGACGTG 1 chrI:7926427-7926507 ( 43) TTCACGTC 1 chrII:372387-372467 ( 51) TCGACGTC 1 chrV:20421688-20421768 ( 36) GTGACGTG 1 chrII:9624263-9624343 ( 26) CACACGTC 1 chrV:15578504-15578584 ( 10) CCGACGTC 1 chrII:7864374-7864454 ( 23) CTCACGTC 1 chrX:5486106-5486186 ( 57) TTGACGTC 1 chrX:4529052-4529132 ( 6) TCCACGTG 1 chrX:5298302-5298382 ( 53) TTGACGTC 1 chrI:5550565-5550645 ( 10) ACCACGTC 1 chrV:20493708-20493788 ( 59) TCCACGTG 1 chrIV:7982204-7982284 ( 37) TACACGTG 1 chrV:10873347-10873427 ( 41) TACACGTG 1 chrIII:8133469-8133549 ( 44) TACACGTG 1 chrI:8529522-8529602 ( 29) TACACGTG 1 chrV:8026523-8026603 ( 38) CCCACGTG 1 chrIV:1973551-1973631 ( 33) CTGACGTC 1 chrIV:9386182-9386262 ( 62) ATCACGTC 1 chrV:20415573-20415653 ( 64) ACGACGTC 1 chrIV:8826769-8826849 ( 62) TCGACGTG 1 chrIV:15028999-15029079 ( 3) CACACGTG 1 chrX:4520115-4520195 ( 33) TCGACGTG 1 chrI:1808017-1808097 ( 4) AAGACGTC 1 chrI:4805450-4805530 ( 38) CCGACGTG 1 chrIII:8405595-8405675 ( 5) AAGACGTC 1 chrIV:4024782-4024862 ( 16) ATGACGTC 1 chrX:17216410-17216490 ( 49) ACCACGTG 1 chrV:6095991-6096071 ( 29) TTGACGTG 1 chrI:4671878-4671958 ( 60) CTGACGTG 1 chrI:2045091-2045171 ( 61) AACACGTG 1 chrX:6020206-6020286 ( 26) AACACGTG 1 chrV:20269947-20270027 ( 68) CTGACGTG 1 chrIV:17288072-17288152 ( 34) CTGACGTG 1 chrII:8566184-8566264 ( 30) CTGACGTG 1 chrX:4524972-4525052 ( 62) CTGACGTG 1 chrX:6836263-6836343 ( 32) AACACGTG 1 chrII:161322-161402 ( 13) AAGACGTG 1 chrII:7352677-7352757 ( 44) ATGACGTG 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif KHSACGTS MEME-2 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 9.8035 E= 1.2e-016 -67 -27 80 -12 39 49 -1277 23 -1277 127 104 -1277 187 -1277 -1277 -1277 -1277 216 -1277 -1277 -1277 -1277 217 -1277 -1277 -1277 -1277 183 -1277 138 90 -1277 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif KHSACGTS MEME-2 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 70 E= 1.2e-016 0.171429 0.185714 0.385714 0.257143 0.357143 0.314286 0.000000 0.328571 0.000000 0.542857 0.457143 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.585714 0.414286 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif KHSACGTS MEME-2 regular expression -------------------------------------------------------------------------------- [GT][ATC][CG]ACGT[CG] -------------------------------------------------------------------------------- Time 14.80 secs. ******************************************************************************** ******************************************************************************** MOTIF AAACGCGC MEME-3 width = 8 sites = 28 llr = 255 E-value = 1.1e-006 ******************************************************************************** -------------------------------------------------------------------------------- Motif AAACGCGC MEME-3 Description -------------------------------------------------------------------------------- Simplified A 97a11::: pos.-specific C 13:9:9:a probability G ::::91a: matrix T :::1:::: bits 2.2 ** 2.0 ** 1.7 * * ** 1.5 * * **** Relative 1.3 * ****** Entropy 1.1 * ****** (13.1 bits) 0.9 ******** 0.7 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel AAACGCGC consensus C sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAACGCGC MEME-3 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chrIII:634719-634799 28 1.13e-05 TCTGCACCAG AAACGCGC AAAGCTTCTC chrIV:4184941-4185021 58 1.13e-05 CTCGACGAGT AAACGCGC TCCATTGAAC chrIV:992163-992243 22 1.13e-05 TCTCCGGTGC AAACGCGC TCCACCGcac chrIV:2349074-2349154 21 1.13e-05 GCACGTCAAG AAACGCGC CAGCAGACTT chrII:6321169-6321249 31 1.13e-05 GGGAGTAAGC AAACGCGC TCTGTCGAGA chrX:4588082-4588162 37 1.13e-05 ACAGCACGCA AAACGCGC CAACCGTTAC chrI:3600840-3600920 45 1.13e-05 AATGGGAGGA AAACGCGC CCCATCGCAC chrII:1402321-1402401 36 1.13e-05 CACTAACGCA AAACGCGC CAGCAGCCAC chrIV:3694812-3694892 37 2.05e-05 GCTCTACCGC ACACGCGC TGCGCCGCGA chrIII:1037333-1037413 25 2.05e-05 AGCGATCGAG ACACGCGC CAGCAAAATT chrI:3070214-3070294 46 2.05e-05 GCACTAAACA ACACGCGC ATGCGGAATT chrI:10591702-10591782 22 2.05e-05 CGAGAGGAGT ACACGCGC GAGTGCACTG chrII:7874138-7874218 36 2.05e-05 TGTGTAAACA ACACGCGC TTCGTTCTGC chrV:6043427-6043507 33 2.05e-05 TCGAATTTGA ACACGCGC CAATTTGAGG chrV:12184461-12184541 30 2.05e-05 TTGATAAACT ACACGCGC ATCGTTATAT chrIV:12209165-12209245 19 2.98e-05 TTACGGTAAA CAACGCGC GATTCGTAAT chrII:8429110-8429190 34 2.98e-05 GCGCACTAAA CAACGCGC AAACTATTGT chrIV:9403872-9403952 23 4.09e-05 ATTTGAGGAA AAACGGGC GAAAATGAGC chrI:5937068-5937148 10 4.09e-05 AAGCAGGAT AAACGGGC CTGGCACAGG chrIV:813520-813600 11 6.88e-05 CCACCACGAG AAATGCGC AGAGAGAGCG chrX:6729728-6729808 58 6.88e-05 AGAGAAATGT AAATGCGC TCCATTGAAC chrI:12572472-12572552 68 6.88e-05 TGTCTTGGAG AAAAGCGC GGAGA chrI:3019639-3019719 32 9.18e-05 AAAAGGTGGA AAACACGC AACAAATGAG chrV:11327137-11327217 17 9.18e-05 GTGTGTACGC AAACACGC ATTGGCAACC chrV:8652331-8652411 38 9.18e-05 ACGTCGTCTA AGACGCGC GGGTGGCGCG chrX:5298302-5298382 44 1.09e-04 ATGAGCTAGT AACCGCGC GTTGACGTCA chrII:13083908-13083988 6 1.41e-04 TTGAA ACAAGCGC CAAAAAGTGG chrI:323626-323706 52 1.66e-04 TTTTTCAGCA AAACGTGC ATAAAAAAAT -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAACGCGC MEME-3 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chrIII:634719-634799 1.1e-05 27_[+3]_45 chrIV:4184941-4185021 1.1e-05 57_[+3]_15 chrIV:992163-992243 1.1e-05 21_[+3]_51 chrIV:2349074-2349154 1.1e-05 20_[+3]_52 chrII:6321169-6321249 1.1e-05 30_[+3]_42 chrX:4588082-4588162 1.1e-05 36_[+3]_36 chrI:3600840-3600920 1.1e-05 44_[+3]_28 chrII:1402321-1402401 1.1e-05 35_[+3]_37 chrIV:3694812-3694892 2.1e-05 36_[+3]_36 chrIII:1037333-1037413 2.1e-05 24_[+3]_48 chrI:3070214-3070294 2.1e-05 45_[+3]_27 chrI:10591702-10591782 2.1e-05 21_[+3]_51 chrII:7874138-7874218 2.1e-05 35_[+3]_37 chrV:6043427-6043507 2.1e-05 32_[+3]_40 chrV:12184461-12184541 2.1e-05 29_[+3]_43 chrIV:12209165-12209245 3e-05 18_[+3]_54 chrII:8429110-8429190 3e-05 33_[+3]_39 chrIV:9403872-9403952 4.1e-05 22_[+3]_50 chrI:5937068-5937148 4.1e-05 9_[+3]_63 chrIV:813520-813600 6.9e-05 10_[+3]_62 chrX:6729728-6729808 6.9e-05 57_[+3]_15 chrI:12572472-12572552 6.9e-05 67_[+3]_5 chrI:3019639-3019719 9.2e-05 31_[+3]_41 chrV:11327137-11327217 9.2e-05 16_[+3]_56 chrV:8652331-8652411 9.2e-05 37_[+3]_35 chrX:5298302-5298382 0.00011 43_[+3]_29 chrII:13083908-13083988 0.00014 5_[+3]_67 chrI:323626-323706 0.00017 51_[+3]_21 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAACGCGC MEME-3 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF AAACGCGC width=8 seqs=28 chrIII:634719-634799 ( 28) AAACGCGC 1 chrIV:4184941-4185021 ( 58) AAACGCGC 1 chrIV:992163-992243 ( 22) AAACGCGC 1 chrIV:2349074-2349154 ( 21) AAACGCGC 1 chrII:6321169-6321249 ( 31) AAACGCGC 1 chrX:4588082-4588162 ( 37) AAACGCGC 1 chrI:3600840-3600920 ( 45) AAACGCGC 1 chrII:1402321-1402401 ( 36) AAACGCGC 1 chrIV:3694812-3694892 ( 37) ACACGCGC 1 chrIII:1037333-1037413 ( 25) ACACGCGC 1 chrI:3070214-3070294 ( 46) ACACGCGC 1 chrI:10591702-10591782 ( 22) ACACGCGC 1 chrII:7874138-7874218 ( 36) ACACGCGC 1 chrV:6043427-6043507 ( 33) ACACGCGC 1 chrV:12184461-12184541 ( 30) ACACGCGC 1 chrIV:12209165-12209245 ( 19) CAACGCGC 1 chrII:8429110-8429190 ( 34) CAACGCGC 1 chrIV:9403872-9403952 ( 23) AAACGGGC 1 chrI:5937068-5937148 ( 10) AAACGGGC 1 chrIV:813520-813600 ( 11) AAATGCGC 1 chrX:6729728-6729808 ( 58) AAATGCGC 1 chrI:12572472-12572552 ( 68) AAAAGCGC 1 chrI:3019639-3019719 ( 32) AAACACGC 1 chrV:11327137-11327217 ( 17) AAACACGC 1 chrV:8652331-8652411 ( 38) AGACGCGC 1 chrX:5298302-5298382 ( 44) AACCGCGC 1 chrII:13083908-13083988 ( 6) ACAAGCGC 1 chrI:323626-323706 ( 52) AAACGTGC 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAACGCGC MEME-3 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 9.18967 E= 1.1e-006 177 -165 -1145 -1145 131 35 -263 -1145 182 -265 -1145 -1145 -193 193 -1145 -197 -193 -1145 206 -1145 -1145 199 -164 -297 -1145 -1145 217 -1145 -1145 216 -1145 -1145 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAACGCGC MEME-3 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 28 E= 1.1e-006 0.928571 0.071429 0.000000 0.000000 0.678571 0.285714 0.035714 0.000000 0.964286 0.035714 0.000000 0.000000 0.071429 0.857143 0.000000 0.071429 0.071429 0.000000 0.928571 0.000000 0.000000 0.892857 0.071429 0.035714 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAACGCGC MEME-3 regular expression -------------------------------------------------------------------------------- A[AC]ACGCGC -------------------------------------------------------------------------------- Time 18.41 secs. ******************************************************************************** ******************************************************************************** MOTIF GAGACGCA MEME-4 width = 8 sites = 15 llr = 162 E-value = 1.2e-006 ******************************************************************************** -------------------------------------------------------------------------------- Motif GAGACGCA MEME-4 Description -------------------------------------------------------------------------------- Simplified A :a:a:::9 pos.-specific C ::::a1a1 probability G a:a::9:: matrix T :::::::: bits 2.2 * * * * 2.0 ***** * 1.7 ***** * 1.5 ******** Relative 1.3 ******** Entropy 1.1 ******** (15.5 bits) 0.9 ******** 0.7 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel GAGACGCA consensus sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GAGACGCA MEME-4 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chrIV:9335984-9336064 14 1.12e-05 AGTTTAGAAA GAGACGCA GGCATTGAGA chrI:14710999-14711079 60 1.12e-05 TGCAAAGCGA GAGACGCA GAGTCTGCTA chrI:814038-814118 31 1.12e-05 TAACCAATCA GAGACGCA CACACCGCAC chrII:3616769-3616849 28 1.12e-05 CGTCACATTT GAGACGCA GGCAGGCAGC chrIII:13152812-13152892 43 1.12e-05 GCGAAATCGA GAGACGCA GAGAAGCCGC chrI:12106427-12106507 28 1.12e-05 CTGAACAGCG GAGACGCA GACAGCTAAG chrII:7090306-7090386 45 1.12e-05 GCGAGAAAGA GAGACGCA GGCTGACTGC chrIV:14083120-14083200 54 1.12e-05 AGAGAGTGAA GAGACGCA GACACTCTAA chrIII:4998411-4998491 45 1.12e-05 CAGTCGTCGT GAGACGCA GAACAAATAG chrX:4522574-4522654 58 1.12e-05 GTGGTTGCGA GAGACGCA GTGATAGAGA chrIII:11378580-11378660 12 1.12e-05 ATAAGAAAAC GAGACGCA GAAATGAGTA chrX:6836263-6836343 47 1.12e-05 GTGCAAAGGG GAGACGCA GGCAGGTACA chrIII:8029643-8029723 70 2.24e-05 TGGTCGCGGC GAGACCCA TTC chrV:20269947-20270027 9 2.24e-05 GGCGTTGC GAGACCCA ACACACACGA chrIV:3519551-3519631 10 3.16e-05 AGAAATGGA GAGACGCC GACAGACCGA -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GAGACGCA MEME-4 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chrIV:9335984-9336064 1.1e-05 13_[+4]_59 chrI:14710999-14711079 1.1e-05 59_[+4]_13 chrI:814038-814118 1.1e-05 30_[+4]_42 chrII:3616769-3616849 1.1e-05 27_[+4]_45 chrIII:13152812-13152892 1.1e-05 42_[+4]_30 chrI:12106427-12106507 1.1e-05 27_[+4]_45 chrII:7090306-7090386 1.1e-05 44_[+4]_28 chrIV:14083120-14083200 1.1e-05 53_[+4]_19 chrIII:4998411-4998491 1.1e-05 44_[+4]_28 chrX:4522574-4522654 1.1e-05 57_[+4]_15 chrIII:11378580-11378660 1.1e-05 11_[+4]_61 chrX:6836263-6836343 1.1e-05 46_[+4]_26 chrIII:8029643-8029723 2.2e-05 69_[+4]_3 chrV:20269947-20270027 2.2e-05 8_[+4]_64 chrIV:3519551-3519631 3.2e-05 9_[+4]_63 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GAGACGCA MEME-4 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF GAGACGCA width=8 seqs=15 chrIV:9335984-9336064 ( 14) GAGACGCA 1 chrI:14710999-14711079 ( 60) GAGACGCA 1 chrI:814038-814118 ( 31) GAGACGCA 1 chrII:3616769-3616849 ( 28) GAGACGCA 1 chrIII:13152812-13152892 ( 43) GAGACGCA 1 chrI:12106427-12106507 ( 28) GAGACGCA 1 chrII:7090306-7090386 ( 45) GAGACGCA 1 chrIV:14083120-14083200 ( 54) GAGACGCA 1 chrIII:4998411-4998491 ( 45) GAGACGCA 1 chrX:4522574-4522654 ( 58) GAGACGCA 1 chrIII:11378580-11378660 ( 12) GAGACGCA 1 chrX:6836263-6836343 ( 47) GAGACGCA 1 chrIII:8029643-8029723 ( 70) GAGACCCA 1 chrV:20269947-20270027 ( 9) GAGACCCA 1 chrIV:3519551-3519631 ( 10) GAGACGCC 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GAGACGCA MEME-4 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 10.1725 E= 1.2e-006 -1055 -1055 217 -1055 187 -1055 -1055 -1055 -1055 -1055 217 -1055 187 -1055 -1055 -1055 -1055 216 -1055 -1055 -1055 -75 196 -1055 -1055 216 -1055 -1055 177 -175 -1055 -1055 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GAGACGCA MEME-4 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 15 E= 1.2e-006 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.133333 0.866667 0.000000 0.000000 1.000000 0.000000 0.000000 0.933333 0.066667 0.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GAGACGCA MEME-4 regular expression -------------------------------------------------------------------------------- GAGACGCA -------------------------------------------------------------------------------- Time 21.86 secs. ******************************************************************************** ******************************************************************************** MOTIF YGKTGTTT MEME-5 width = 8 sites = 31 llr = 273 E-value = 1.9e-005 ******************************************************************************** -------------------------------------------------------------------------------- Motif YGKTGTTT MEME-5 Description -------------------------------------------------------------------------------- Simplified A :::::::: pos.-specific C 63:::::: probability G :75:a::: matrix T 4:5a:aaa bits 2.2 2.0 * 1.7 ***** 1.5 ***** Relative 1.3 * ***** Entropy 1.1 ******** (12.7 bits) 0.9 ******** 0.7 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel CGTTGTTT consensus TCG sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YGKTGTTT MEME-5 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chrIII:8631015-8631095 43 1.51e-05 TTTACCGTGA CGGTGTTT GCAGACAGCT chrIII:3855017-3855097 2 1.51e-05 T CGGTGTTT GCACACAAAA chrII:7864374-7864454 32 1.51e-05 TCTCACGTCA CGGTGTTT GCGGTCCGTC chrIV:8113290-8113370 50 1.51e-05 TTTTGCGTGA CGGTGTTT GCGTACAATA chrI:7129604-7129684 14 1.51e-05 AAAGATCTAT CGGTGTTT GTGTGACGTG chrIV:1973551-1973631 19 1.51e-05 CGGTACCCGG CGGTGTTT GCACTGCTGA chrV:1196153-1196233 67 3.41e-05 TTCGGAGTGT CGTTGTTT TATATT chrIV:7512991-7513071 57 3.41e-05 TCCCACCGCG CGTTGTTT ACCGTAAAAC chrII:7874138-7874218 62 3.41e-05 GCTGGAGTGT CGTTGTTT GCTAAAAAAC chrV:5939667-5939747 60 3.41e-05 CCCTACTGCG CGTTGTTT ATTCTCGTAA chrI:6038169-6038249 60 3.41e-05 ATCGGAGTGT CGTTGTTT ATTTTCAATT chrI:6949429-6949509 45 3.41e-05 TTCGGAGCTT CGTTGTTT CGTTTGAAAA chrV:8652331-8652411 58 3.41e-05 GTGGCGCGAG CGTTGTTT GAAATTTGTT chrII:8429110-8429190 7 5.29e-05 GACCAG TGGTGTTT GCACACAATG chrI:13840071-13840151 16 5.29e-05 TCGTCAGATT TGGTGTTT GCGTACAAAG chrI:5550565-5550645 30 5.29e-05 ACTGCCCTTC TGGTGTTT GCGGACAACA chrIV:11142601-11142681 33 5.29e-05 TCGTCATTTG TGGTGTTT GCGTATTTTT chrIII:11774659-11774739 26 5.29e-05 CACCGTTTTC TGGTGTTT TGTACGCAAA chrV:6095991-6096071 38 5.29e-05 CTTGACGTGA TGGTGTTT GCACACTTTT chrIV:4024782-4024862 49 7.66e-05 CAATTGTTGA TGTTGTTT GAAGCGAGGA chrII:9242971-9243051 56 7.66e-05 CTGTGGCACG TGTTGTTT ACCGTAAATC chrIV:2890724-2890804 57 7.66e-05 CCGCATCGCG TGTTGTTT AGCCAGCGGG chrII:8811173-8811253 36 9.18e-05 TCTGCCGTCA CCGTGTTT GCGTATATTT chrI:7069265-7069345 36 1.11e-04 CGCAACAGCG CCTTGTTT ATCGTAAATC chrV:15578504-15578584 38 1.11e-04 TGCGCCGGAG CCTTGTTT AGCGTAAATC chrIII:1905771-1905851 37 1.11e-04 TAGGCGCGCG CCTTGTTT AGACCGTTAT chrIV:9525119-9525199 16 1.11e-04 TCGTTGCGCG CCTTGTTT ATCAGTTGTT chrIV:15028999-15029079 23 1.30e-04 TTAGTCGTCG TCGTGTTT GCACACAACT chrII:9669113-9669193 70 1.54e-04 CACTTGCTCG TCTTGTTT ATC chrX:4529052-4529132 18 1.54e-04 CACGTGATTC TCTTGTTT GTAAGCGTGA chrIV:12209165-12209245 65 1.73e-04 GAGTTTGTGG CGGTTTTT CAAATTTC -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YGKTGTTT MEME-5 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chrIII:8631015-8631095 1.5e-05 42_[+5]_30 chrIII:3855017-3855097 1.5e-05 1_[+5]_71 chrII:7864374-7864454 1.5e-05 31_[+5]_41 chrIV:8113290-8113370 1.5e-05 49_[+5]_23 chrI:7129604-7129684 1.5e-05 13_[+5]_59 chrIV:1973551-1973631 1.5e-05 18_[+5]_54 chrV:1196153-1196233 3.4e-05 66_[+5]_6 chrIV:7512991-7513071 3.4e-05 56_[+5]_16 chrII:7874138-7874218 3.4e-05 61_[+5]_11 chrV:5939667-5939747 3.4e-05 59_[+5]_13 chrI:6038169-6038249 3.4e-05 59_[+5]_13 chrI:6949429-6949509 3.4e-05 44_[+5]_28 chrV:8652331-8652411 3.4e-05 57_[+5]_15 chrII:8429110-8429190 5.3e-05 6_[+5]_66 chrI:13840071-13840151 5.3e-05 15_[+5]_57 chrI:5550565-5550645 5.3e-05 29_[+5]_43 chrIV:11142601-11142681 5.3e-05 32_[+5]_40 chrIII:11774659-11774739 5.3e-05 25_[+5]_47 chrV:6095991-6096071 5.3e-05 37_[+5]_35 chrIV:4024782-4024862 7.7e-05 48_[+5]_24 chrII:9242971-9243051 7.7e-05 55_[+5]_17 chrIV:2890724-2890804 7.7e-05 56_[+5]_16 chrII:8811173-8811253 9.2e-05 35_[+5]_37 chrI:7069265-7069345 0.00011 35_[+5]_37 chrV:15578504-15578584 0.00011 37_[+5]_35 chrIII:1905771-1905851 0.00011 36_[+5]_36 chrIV:9525119-9525199 0.00011 15_[+5]_57 chrIV:15028999-15029079 0.00013 22_[+5]_50 chrII:9669113-9669193 0.00015 69_[+5]_3 chrX:4529052-4529132 0.00015 17_[+5]_55 chrIV:12209165-12209245 0.00017 64_[+5]_8 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YGKTGTTT MEME-5 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF YGKTGTTT width=8 seqs=31 chrIII:8631015-8631095 ( 43) CGGTGTTT 1 chrIII:3855017-3855097 ( 2) CGGTGTTT 1 chrII:7864374-7864454 ( 32) CGGTGTTT 1 chrIV:8113290-8113370 ( 50) CGGTGTTT 1 chrI:7129604-7129684 ( 14) CGGTGTTT 1 chrIV:1973551-1973631 ( 19) CGGTGTTT 1 chrV:1196153-1196233 ( 67) CGTTGTTT 1 chrIV:7512991-7513071 ( 57) CGTTGTTT 1 chrII:7874138-7874218 ( 62) CGTTGTTT 1 chrV:5939667-5939747 ( 60) CGTTGTTT 1 chrI:6038169-6038249 ( 60) CGTTGTTT 1 chrI:6949429-6949509 ( 45) CGTTGTTT 1 chrV:8652331-8652411 ( 58) CGTTGTTT 1 chrII:8429110-8429190 ( 7) TGGTGTTT 1 chrI:13840071-13840151 ( 16) TGGTGTTT 1 chrI:5550565-5550645 ( 30) TGGTGTTT 1 chrIV:11142601-11142681 ( 33) TGGTGTTT 1 chrIII:11774659-11774739 ( 26) TGGTGTTT 1 chrV:6095991-6096071 ( 38) TGGTGTTT 1 chrIV:4024782-4024862 ( 49) TGTTGTTT 1 chrII:9242971-9243051 ( 56) TGTTGTTT 1 chrIV:2890724-2890804 ( 57) TGTTGTTT 1 chrII:8811173-8811253 ( 36) CCGTGTTT 1 chrI:7069265-7069345 ( 36) CCTTGTTT 1 chrV:15578504-15578584 ( 38) CCTTGTTT 1 chrIII:1905771-1905851 ( 37) CCTTGTTT 1 chrIV:9525119-9525199 ( 16) CCTTGTTT 1 chrIV:15028999-15029079 ( 23) TCGTGTTT 1 chrII:9669113-9669193 ( 70) TCTTGTTT 1 chrX:4529052-4529132 ( 18) TCTTGTTT 1 chrIV:12209165-12209245 ( 65) CGGTTTTT 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YGKTGTTT MEME-5 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 9.16214 E= 1.9e-005 -1160 145 -1160 47 -1160 20 174 -1160 -1160 -1160 112 88 -1160 -1160 -1160 183 -1160 -1160 212 -312 -1160 -1160 -1160 183 -1160 -1160 -1160 183 -1160 -1160 -1160 183 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YGKTGTTT MEME-5 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 31 E= 1.9e-005 0.000000 0.612903 0.000000 0.387097 0.000000 0.258065 0.741935 0.000000 0.000000 0.000000 0.483871 0.516129 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.967742 0.032258 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YGKTGTTT MEME-5 regular expression -------------------------------------------------------------------------------- [CT][GC][TG]TGTTT -------------------------------------------------------------------------------- Time 25.32 secs. ******************************************************************************** ******************************************************************************** SUMMARY OF MOTIFS ******************************************************************************** -------------------------------------------------------------------------------- Combined block diagrams: non-overlapping sites with p-value < 0.0001 -------------------------------------------------------------------------------- SEQUENCE NAME COMBINED P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chrII:7352677-7352757 1.52e-01 80 chrV:9860482-9860562 2.19e-01 80 chrIV:1973551-1973631 6.09e-03 18_[+5(1.51e-05)]_54 chrX:6836263-6836343 9.19e-04 46_[+4(1.12e-05)]_26 chrX:4524972-4525052 6.89e-01 80 chrI:14662959-14663039 2.83e-01 80 chrII:12237693-12237773 8.95e-01 80 chrII:9624263-9624343 2.70e-03 55_[+1(1.19e-05)]_17 chrV:1570115-1570195 4.89e-01 80 chrV:20421688-20421768 6.42e-02 80 chrIII:3469819-3469899 8.59e-01 80 chrX:4520115-4520195 3.21e-02 80 chrV:6095991-6096071 2.33e-03 37_[+5(5.29e-05)]_35 chrIII:7296315-7296395 4.96e-01 80 chrX:12725133-12725213 3.72e-02 80 chrII:8811173-8811253 2.69e-02 35_[+5(9.18e-05)]_37 chrX:10656772-10656852 6.00e-01 80 chrI:4302373-4302453 3.48e-02 21_[+4(4.09e-05)]_51 chrIV:5582895-5582975 2.98e-01 80 chrIII:11378580-11378660 3.26e-02 11_[+4(1.12e-05)]_61 chrX:4516944-4517024 2.68e-02 48_[+1(4.81e-05)]_24 chrV:6930325-6930405 5.54e-02 7_[+2(9.48e-06)]_65 chrX:4522574-4522654 1.40e-03 57_[+4(1.12e-05)]_15 chrI:14358435-14358515 4.74e-02 80 chrX:12861132-12861212 2.40e-01 80 chrIV:11125367-11125447 7.39e-02 80 chrIII:9571015-9571095 5.09e-01 80 chrX:6093047-6093127 4.32e-03 71_[+1(1.19e-05)]_1 chrIII:647350-647430 2.41e-03 2_[+2(9.48e-06)]_70 chrX:15083961-15084041 1.12e-01 80 chrV:8026523-8026603 1.69e-02 80 chrI:12572472-12572552 1.23e-03 28_[+2(4.23e-05)]_31_[+3(6.88e-05)]_\ 5 chrIII:4367752-4367832 6.05e-01 80 chrIII:4998411-4998491 1.94e-02 44_[+4(1.12e-05)]_28 chrIII:11935411-11935491 3.00e-01 80 chrX:7194044-7194124 9.89e-01 80 chrIII:3470856-3470936 5.58e-01 80 chrII:372387-372467 2.82e-02 80 chrIV:14083120-14083200 7.72e-03 53_[+4(1.12e-05)]_19 chrIV:15028999-15029079 8.49e-03 80 chrII:12224185-12224265 6.54e-01 80 chrV:12560516-12560596 1.40e-02 80 chrIII:12009881-12009961 8.36e-02 27_[+2(9.48e-06)]_45 chrIII:6402445-6402525 2.67e-02 24_[+2(9.48e-06)]_48 chrII:7356958-7357038 5.45e-02 80 chrX:17216410-17216490 1.60e-01 80 chrII:8566184-8566264 2.73e-01 80 chrX:7100425-7100505 1.47e-02 36_[+1(1.19e-05)]_36 chrIV:4686602-4686682 2.10e-01 80 chrII:12953528-12953608 2.45e-01 80 chrI:10683120-10683200 3.29e-02 51_[+1(1.19e-05)]_21 chrIV:8826769-8826849 6.54e-02 80 chrV:8302665-8302745 6.92e-04 11_[+2(2.10e-05)]_61 chrV:20493708-20493788 1.15e-01 80 chrII:5429850-5429930 9.54e-04 51_[+1(4.81e-05)]_21 chrI:14946810-14946890 3.16e-02 80 chrV:12409179-12409259 8.11e-01 80 chrIV:17288072-17288152 1.68e-02 80 chrI:8529522-8529602 2.33e-01 80 chrIII:13383328-13383408 3.34e-01 80 chrX:4219693-4219773 7.31e-01 80 chrX:7067703-7067783 6.48e-01 80 chrI:5420441-5420521 1.53e-01 80 chrV:20269947-20270027 3.06e-03 8_[+4(2.24e-05)]_64 chrIV:1056625-1056705 7.20e-01 80 chrIII:11774659-11774739 1.34e-03 2_[+2(2.10e-05)]_15_[+5(5.29e-05)]_\ 47 chrII:8661712-8661792 2.79e-03 29_[+2(7.49e-05)]_43 chrX:6052911-6052991 2.63e-01 80 chrIII:6625449-6625529 9.97e-02 80 chrV:9729912-9729992 1.90e-02 80 chrIV:11142601-11142681 1.69e-03 32_[+5(5.29e-05)]_40 chrX:12860922-12861002 1.66e-01 80 chrIV:11112066-11112146 2.41e-02 26_[+2(9.48e-06)]_46 chrV:8652331-8652411 3.19e-05 24_[+2(7.49e-05)]_5_[+3(9.18e-05)]_\ 12_[+5(3.41e-05)]_15 chrX:16401081-16401161 1.62e-03 80 chrI:13807424-13807504 2.87e-01 80 chrI:4792621-4792701 2.68e-02 63_[+2(7.49e-05)]_9 chrI:5550565-5550645 5.62e-03 29_[+5(5.29e-05)]_43 chrX:7066090-7066170 8.61e-01 80 chrIV:11298707-11298787 2.34e-01 80 chrIII:8133469-8133549 3.44e-01 80 chrIII:8405595-8405675 4.98e-02 80 chrX:6204994-6205074 4.37e-01 80 chrII:9759575-9759655 9.09e-01 80 chrIII:3701762-3701842 5.23e-02 31_[+2(2.10e-05)]_41 chrI:6949429-6949509 3.00e-02 44_[+5(3.41e-05)]_28 chrI:6038169-6038249 3.03e-02 59_[+5(3.41e-05)]_13 chrII:7090306-7090386 1.01e-02 44_[+4(1.12e-05)]_28 chrI:5937068-5937148 7.30e-02 9_[+3(4.09e-05)]_63 chrIII:12711380-12711460 1.15e-01 80 chrV:10873347-10873427 8.94e-02 80 chrIV:9260508-9260588 5.77e-01 80 chrV:17870724-17870804 2.65e-03 36_[+1(1.19e-05)]_36 chrIV:11026790-11026870 9.60e-01 80 chrIII:12345119-12345199 3.26e-01 80 chrIII:4275825-4275905 5.09e-01 80 chrI:12974146-12974226 8.22e-01 80 chrV:9856613-9856693 6.23e-01 80 chrX:6934608-6934688 4.63e-02 5_[+1(9.38e-05)]_67 chrIV:9525119-9525199 1.01e-01 80 chrI:7926427-7926507 4.91e-02 80 chrIV:8975084-8975164 5.25e-01 80 chrX:6020206-6020286 7.69e-02 80 chrV:11503495-11503575 3.98e-02 80 chrI:12106427-12106507 9.59e-03 27_[+4(1.12e-05)]_9_[+4(6.14e-05)]_\ 28 chrI:7747574-7747654 6.94e-01 80 chrI:2045091-2045171 2.48e-02 80 chrI:7129604-7129684 1.68e-03 13_[+5(1.51e-05)]_59 chrIV:2896157-2896237 3.15e-02 66_[+1(3.63e-05)]_6 chrV:5939667-5939747 9.59e-03 59_[+5(3.41e-05)]_13 chrII:12931583-12931663 2.60e-01 80 chrI:13840071-13840151 2.12e-04 15_[+5(5.29e-05)]_57 chrX:3772597-3772677 1.69e-02 22_[+1(4.81e-05)]_50 chrIV:16034487-16034567 1.16e-01 80 chrIV:8113290-8113370 5.61e-02 49_[+5(1.51e-05)]_23 chrX:17002159-17002239 5.52e-01 80 chrV:20415573-20415653 3.90e-01 80 chrIII:6009116-6009196 2.23e-01 80 chrI:13161984-13162064 9.73e-01 80 chrIII:13152812-13152892 6.61e-04 42_[+4(1.12e-05)]_30 chrII:161322-161402 2.37e-01 80 chrII:3616769-3616849 2.24e-03 27_[+4(1.12e-05)]_45 chrV:11733652-11733732 1.14e-01 35_[+1(2.15e-05)]_37 chrIV:9403872-9403952 9.76e-02 22_[+3(4.09e-05)]_50 chrV:10661636-10661716 1.65e-01 80 chrIII:3705132-3705212 3.95e-01 80 chrIV:17285446-17285526 3.32e-02 28_[+2(2.10e-05)]_44 chrI:14570432-14570512 2.57e-01 80 chrIV:8869789-8869869 5.14e-01 80 chrV:19190137-19190217 8.76e-01 80 chrX:6505174-6505254 1.02e-01 80 chrI:1895095-1895175 2.45e-01 80 chrI:4805450-4805530 3.00e-02 15_[+1(6.96e-05)]_57 chrI:814038-814118 2.58e-02 30_[+4(1.12e-05)]_42 chrV:12184461-12184541 1.68e-03 29_[+3(2.05e-05)]_43 chrI:14839813-14839893 5.50e-01 80 chrII:7864374-7864454 4.06e-03 31_[+5(1.51e-05)]_41 chrII:10300522-10300602 1.69e-02 22_[+2(7.49e-05)]_1_[+2(9.48e-06)]_\ 41 chrV:10002937-10003017 4.67e-03 57_[+2(5.38e-05)]_15 chrV:6043427-6043507 5.24e-02 32_[+3(2.05e-05)]_40 chrII:7874138-7874218 2.09e-04 35_[+3(2.05e-05)]_18_[+5(3.41e-05)]_\ 11 chrIV:12605528-12605608 7.23e-02 80 chrIII:10903331-10903411 1.30e-03 49_[+2(9.48e-06)]_23 chrX:5298302-5298382 2.24e-03 80 chrX:4529052-4529132 2.91e-02 80 chrX:11415028-11415108 7.39e-01 80 chrI:10591702-10591782 4.38e-02 21_[+3(2.05e-05)]_51 chrIV:2890724-2890804 2.13e-02 56_[+5(7.66e-05)]_16 chrIV:1953277-1953357 5.09e-01 80 chrV:19949505-19949585 1.01e-01 80 chrX:14513628-14513708 1.97e-02 80 chrII:1402321-1402401 2.15e-02 35_[+3(1.13e-05)]_37 chrII:13477367-13477447 2.57e-02 37_[+1(3.63e-05)]_35 chrX:4818428-4818508 2.60e-01 80 chrII:4828195-4828275 1.46e-02 56_[+1(3.63e-05)]_16 chrIV:11521102-11521182 2.13e-04 39_[+2(7.49e-05)]_33 chrV:4063712-4063792 9.84e-01 80 chrIV:9534495-9534575 9.24e-02 80 chrI:2668664-2668744 1.36e-01 8_[+2(7.49e-05)]_64 chrI:1808017-1808097 1.75e-03 80 chrI:9141742-9141822 1.14e-01 80 chrII:13083908-13083988 1.41e-01 80 chrI:4381852-4381932 4.19e-01 80 chrIV:132271-132351 4.02e-01 80 chrX:6729728-6729808 7.63e-02 57_[+3(6.88e-05)]_15 chrI:3600840-3600920 1.75e-02 44_[+3(1.13e-05)]_28 chrII:9242971-9243051 3.27e-02 55_[+5(7.66e-05)]_17 chrX:6240436-6240516 2.96e-01 80 chrIV:5160329-5160409 6.75e-02 57_[+1(2.15e-05)]_15 chrIV:2776112-2776192 1.96e-02 63_[+2(7.49e-05)]_9 chrIV:9386182-9386262 1.60e-04 47_[+1(1.19e-05)]_25 chrI:10970244-10970324 5.02e-02 42_[+1(1.19e-05)]_13_[+1(6.96e-05)]_\ 9 chrX:4462560-4462640 9.95e-02 37_[+1(6.96e-05)]_35 chrX:4588082-4588162 1.54e-04 36_[+3(1.13e-05)]_13_[+1(1.19e-05)]_\ 15 chrIII:5499108-5499188 8.17e-02 80 chrII:6321169-6321249 5.58e-03 30_[+3(1.13e-05)]_42 chrI:14953181-14953261 3.70e-01 80 chrIII:4332694-4332774 1.05e-01 80 chrIV:11111381-11111461 3.91e-01 80 chrII:4762702-4762782 4.45e-02 6_[+2(9.48e-06)]_66 chrI:12183243-12183323 7.87e-03 18_[+1(2.15e-05)]_54 chrI:323626-323706 1.10e-01 80 chrIII:3855017-3855097 1.15e-03 1_[+5(1.51e-05)]_71 chrI:14710999-14711079 1.68e-02 59_[+4(1.12e-05)]_13 chrIV:4024782-4024862 5.97e-02 48_[+5(7.66e-05)]_24 chrIV:2349074-2349154 2.21e-06 20_[+3(1.13e-05)]_15_[+1(3.63e-05)]_\ 29 chrIV:5561537-5561617 8.21e-01 80 chrI:663630-663710 4.28e-02 72_[+1(1.19e-05)] chrV:5204322-5204402 5.47e-01 80 chrIV:992163-992243 3.12e-04 21_[+3(1.13e-05)]_51 chrX:7076672-7076752 5.44e-01 80 chrI:8254956-8255036 4.03e-01 80 chrV:10757182-10757262 9.87e-01 80 chrI:3070214-3070294 2.83e-02 45_[+3(2.05e-05)]_27 chrX:5486106-5486186 3.29e-02 80 chrV:18086929-18087009 4.40e-02 26_[+1(3.63e-05)]_21_[+1(1.19e-05)]_\ 17 chrI:13859224-13859304 3.28e-01 80 chrIV:10367977-10368057 1.14e-01 80 chrIV:7512991-7513071 1.44e-03 56_[+5(3.41e-05)]_16 chrIII:1905771-1905851 3.21e-02 80 chrIII:4456736-4456816 3.94e-02 49_[+2(9.48e-06)]_23 chrI:6358548-6358628 4.04e-02 49_[+1(6.96e-05)]_23 chrIII:1037333-1037413 6.75e-05 24_[+3(2.05e-05)]_16_[+1(3.63e-05)]_\ 24 chrI:6626892-6626972 8.76e-01 80 chrV:6110689-6110769 9.65e-01 80 chrIII:8631015-8631095 4.42e-02 42_[+5(1.51e-05)]_30 chrV:6427550-6427630 1.28e-01 80 chrI:7057000-7057080 9.06e-01 80 chrIII:8029643-8029723 3.15e-02 69_[+4(2.24e-05)]_3 chrIII:8432308-8432388 1.59e-01 80 chrIV:7982204-7982284 1.68e-01 80 chrV:6098841-6098921 7.89e-01 80 chrIV:1054887-1054967 1.24e-01 80 chrI:6850029-6850109 3.01e-01 80 chrIV:4720708-4720788 7.14e-02 80 chrIV:3519551-3519631 1.76e-02 9_[+4(3.16e-05)]_63 chrIV:4184941-4185021 7.25e-03 57_[+3(1.13e-05)]_15 chrI:9848137-9848217 3.34e-02 80 chrX:4260459-4260539 2.62e-01 80 chrIII:3650854-3650934 5.34e-02 80 chrX:7233895-7233975 7.48e-01 80 chrII:11676099-11676179 3.74e-02 50_[+1(6.96e-05)]_10_[+1(3.63e-05)]_\ 4 chrIV:11125569-11125649 3.34e-01 80 chrIII:634719-634799 5.63e-05 27_[+3(1.13e-05)]_14_[+1(1.19e-05)]_\ 11_[+1(6.96e-05)]_4 chrV:9128747-9128827 7.16e-01 80 chrX:12990903-12990983 2.05e-02 1_[+1(9.38e-05)]_71 chrII:8429110-8429190 7.79e-06 6_[+5(5.29e-05)]_19_[+3(2.98e-05)]_\ 20_[+2(2.10e-05)]_11 chrIV:4357433-4357513 2.19e-02 59_[+1(1.19e-05)]_13 chrV:11327137-11327217 4.63e-02 16_[+3(9.18e-05)]_56 chrV:15578504-15578584 1.11e-02 80 chrII:386118-386198 4.53e-02 55_[+1(9.38e-05)]_17 chrI:3019639-3019719 7.01e-02 31_[+3(9.18e-05)]_41 chrIV:12029970-12030050 1.40e-01 80 chrI:4671878-4671958 1.24e-01 80 chrIV:14070352-14070432 1.07e-01 27_[+1(1.19e-05)]_22_[+1(2.15e-05)]_\ 15 chrIV:3694812-3694892 1.77e-03 36_[+3(2.05e-05)]_36 chrIII:6489080-6489160 1.66e-01 80 chrIV:9335984-9336064 2.10e-03 13_[+4(1.12e-05)]_59 chrIV:813520-813600 7.39e-02 10_[+3(6.88e-05)]_62 chrII:9669113-9669193 1.70e-01 80 chrIII:2487250-2487330 1.60e-02 17_[+1(4.81e-05)]_55 chrI:7069265-7069345 1.78e-02 80 chrIII:4113795-4113875 5.30e-01 80 chrI:3741265-3741345 3.70e-02 33_[+1(1.19e-05)]_39 chrV:6225611-6225691 8.06e-01 80 chrX:7306593-7306673 6.50e-01 80 chrIII:12152332-12152412 7.12e-03 22_[+1(6.96e-05)]_50 chrIV:12209165-12209245 4.05e-03 18_[+3(2.98e-05)]_54 chrV:1196153-1196233 2.26e-03 38_[+1(4.81e-05)]_20_[+5(3.41e-05)]_\ 6 chrX:4957469-4957549 2.24e-01 80 -------------------------------------------------------------------------------- ******************************************************************************** ******************************************************************************** Stopped because requested number of motifs (5) found. ******************************************************************************** CPU: c27n12.farnam.hpc.yale.internal ********************************************************************************