******************************************************************************** MEME - Motif discovery tool ******************************************************************************** MEME version 5.3.3 (Release date: Sun Feb 7 15:39:52 2021 -0800) For further information on how to interpret these results please access https://meme-suite.org/meme. To get a copy of the MEME Suite software please access https://meme-suite.org. ******************************************************************************** ******************************************************************************** REFERENCE ******************************************************************************** If you use this program in your research, please cite: Timothy L. Bailey and Charles Elkan, "Fitting a mixture model by expectation maximization to discover motifs in biopolymers", Proceedings of the Second International Conference on Intelligent Systems for Molecular Biology, pp. 28-36, AAAI Press, Menlo Park, California, 1994. ******************************************************************************** ******************************************************************************** TRAINING SET ******************************************************************************** PRIMARY SEQUENCES= ../result/final_prediction/worm/fasta/RankLinear2.0_40/ets-7.fasta CONTROL SEQUENCES= --none-- ALPHABET= ACGT Sequence name Weight Length Sequence name Weight Length ------------- ------ ------ ------------- ------ ------ chrII:12756339-12756419 1.0000 80 chrIII:8053590-8053670 1.0000 80 chrIII:8298358-8298438 1.0000 80 chrII:4577582-4577662 1.0000 80 chrI:12731445-12731525 1.0000 80 chrX:11128227-11128307 1.0000 80 chrV:7748366-7748446 1.0000 80 chrII:11644423-11644503 1.0000 80 chrI:2011413-2011493 1.0000 80 chrX:1069166-1069246 1.0000 80 chrV:19719460-19719540 1.0000 80 chrII:5736010-5736090 1.0000 80 chrII:7815545-7815625 1.0000 80 chrI:7715023-7715103 1.0000 80 chrX:16814150-16814230 1.0000 80 chrIII:2780401-2780481 1.0000 80 chrII:11288337-11288417 1.0000 80 chrM:5149-5229 1.0000 80 chrV:14795259-14795339 1.0000 80 chrII:6411752-6411832 1.0000 80 chrII:8897396-8897476 1.0000 80 chrV:4121713-4121793 1.0000 80 chrIV:16407993-16408073 1.0000 80 chrX:14486744-14486824 1.0000 80 chrII:6844649-6844729 1.0000 80 chrM:1752-1832 1.0000 80 chrI:8294053-8294133 1.0000 80 chrM:10030-10110 1.0000 80 chrM:3252-3332 1.0000 80 chrI:933477-933557 1.0000 80 chrIV:3350274-3350354 1.0000 80 chrX:11870605-11870685 1.0000 80 chrIII:3499993-3500073 1.0000 80 chrIII:931564-931644 1.0000 80 chrIV:16403623-16403703 1.0000 80 chrX:15264766-15264846 1.0000 80 chrM:2987-3067 1.0000 80 chrIV:385238-385318 1.0000 80 chrI:7158896-7158976 1.0000 80 chrII:13740977-13741057 1.0000 80 chrI:8783739-8783819 1.0000 80 chrIV:10868952-10869032 1.0000 80 chrIII:432890-432970 1.0000 80 chrI:7715687-7715767 1.0000 80 chrIII:2532797-2532877 1.0000 80 chrX:7478578-7478658 1.0000 80 chrII:3956295-3956375 1.0000 80 chrX:9891920-9892000 1.0000 80 chrM:8247-8327 1.0000 80 chrI:2826884-2826964 1.0000 80 chrII:3880687-3880767 1.0000 80 chrIII:11786090-11786170 1.0000 80 chrIV:5371063-5371143 1.0000 80 chrIV:3521323-3521403 1.0000 80 chrX:5056378-5056458 1.0000 80 chrIV:9048255-9048335 1.0000 80 chrI:11609236-11609316 1.0000 80 chrI:14921362-14921442 1.0000 80 chrM:7082-7162 1.0000 80 chrV:9424643-9424723 1.0000 80 chrII:9308993-9309073 1.0000 80 chrI:10469192-10469272 1.0000 80 chrM:7284-7364 1.0000 80 chrX:7562888-7562968 1.0000 80 chrII:11464608-11464688 1.0000 80 chrIV:9235659-9235739 1.0000 80 chrV:7087727-7087807 1.0000 80 chrI:9564397-9564477 1.0000 80 chrIV:12696759-12696839 1.0000 80 chrIII:4453905-4453985 1.0000 80 chrI:11095869-11095949 1.0000 80 chrIV:13029869-13029949 1.0000 80 chrIII:12984606-12984686 1.0000 80 chrV:19720279-19720359 1.0000 80 chrV:11844965-11845045 1.0000 80 chrIII:8416803-8416883 1.0000 80 chrM:1049-1129 1.0000 80 chrI:13851954-13852034 1.0000 80 chrX:2707856-2707936 1.0000 80 chrIV:9316214-9316294 1.0000 80 chrI:8230067-8230147 1.0000 80 chrII:9707457-9707537 1.0000 80 chrM:9063-9143 1.0000 80 chrI:4032662-4032742 1.0000 80 chrX:10435559-10435639 1.0000 80 chrIII:4947434-4947514 1.0000 80 chrIV:11717296-11717376 1.0000 80 chrX:13007968-13008048 1.0000 80 chrX:3738747-3738827 1.0000 80 chrM:4599-4679 1.0000 80 chrIII:11091831-11091911 1.0000 80 chrI:4175996-4176076 1.0000 80 chrM:6281-6361 1.0000 80 chrII:6741574-6741654 1.0000 80 chrI:3842581-3842661 1.0000 80 chrI:12225396-12225476 1.0000 80 chrX:14691347-14691427 1.0000 80 chrIV:560370-560450 1.0000 80 chrX:14027024-14027104 1.0000 80 chrM:6079-6159 1.0000 80 chrIV:6887831-6887911 1.0000 80 chrV:6053449-6053529 1.0000 80 chrX:6252874-6252954 1.0000 80 chrX:5205689-5205769 1.0000 80 chrV:6223846-6223926 1.0000 80 chrM:10232-10312 1.0000 80 chrII:3374089-3374169 1.0000 80 chrIII:4905440-4905520 1.0000 80 chrM:8453-8533 1.0000 80 chrIII:1824681-1824761 1.0000 80 chrI:11765970-11766050 1.0000 80 chrI:7217535-7217615 1.0000 80 chrM:3556-3636 1.0000 80 chrV:3186513-3186593 1.0000 80 chrII:12042349-12042429 1.0000 80 chrM:2120-2200 1.0000 80 chrI:11785644-11785724 1.0000 80 chrIII:4272814-4272894 1.0000 80 chrII:11537320-11537400 1.0000 80 chrV:5284758-5284838 1.0000 80 chrIV:1711349-1711429 1.0000 80 chrII:14406922-14407002 1.0000 80 chrIII:8650407-8650487 1.0000 80 chrIII:11848517-11848597 1.0000 80 chrII:476194-476274 1.0000 80 chrIII:4280929-4281009 1.0000 80 chrIV:565533-565613 1.0000 80 chrII:5836521-5836601 1.0000 80 chrIII:3476377-3476457 1.0000 80 chrII:7708749-7708829 1.0000 80 chrIV:11639194-11639274 1.0000 80 chrI:1271060-1271140 1.0000 80 chrI:2487823-2487903 1.0000 80 chrI:1416037-1416117 1.0000 80 chrII:11884364-11884444 1.0000 80 chrI:9448087-9448167 1.0000 80 chrII:11534671-11534751 1.0000 80 chrX:8156103-8156183 1.0000 80 chrX:3994557-3994637 1.0000 80 chrII:8927402-8927482 1.0000 80 chrII:8128873-8128953 1.0000 80 chrI:3861577-3861657 1.0000 80 chrI:7251637-7251717 1.0000 80 chrIII:4282719-4282799 1.0000 80 chrM:12383-12463 1.0000 80 chrII:66372-66452 1.0000 80 chrII:6831838-6831918 1.0000 80 chrX:12890273-12890353 1.0000 80 chrX:14115626-14115706 1.0000 80 chrIV:16995567-16995647 1.0000 80 chrV:14688718-14688798 1.0000 80 chrIII:8144742-8144822 1.0000 80 chrX:8386201-8386281 1.0000 80 chrIV:16401096-16401176 1.0000 80 chrIII:6537365-6537445 1.0000 80 chrI:9268937-9269017 1.0000 80 chrIV:14032865-14032945 1.0000 80 chrIV:8016136-8016216 1.0000 80 chrX:3348023-3348103 1.0000 80 chrII:14528379-14528459 1.0000 80 chrIII:3664385-3664465 1.0000 80 chrI:7772627-7772707 1.0000 80 chrI:10642461-10642541 1.0000 80 chrX:16928320-16928400 1.0000 80 chrII:13291583-13291663 1.0000 80 chrIII:7642152-7642232 1.0000 80 chrII:5594377-5594457 1.0000 80 chrIII:9700418-9700498 1.0000 80 chrIV:3233006-3233086 1.0000 80 chrV:4181911-4181991 1.0000 80 chrIII:1122414-1122494 1.0000 80 chrII:6565204-6565284 1.0000 80 chrM:12582-12662 1.0000 80 chrIV:9216709-9216789 1.0000 80 chrII:7001584-7001664 1.0000 80 chrII:15232900-15232980 1.0000 80 chrI:1823232-1823312 1.0000 80 chrX:9337942-9338022 1.0000 80 chrI:3176586-3176666 1.0000 80 chrIV:1981093-1981173 1.0000 80 chrII:6248644-6248724 1.0000 80 chrII:9263157-9263237 1.0000 80 chrII:5966763-5966843 1.0000 80 chrII:14249578-14249658 1.0000 80 chrX:9225546-9225626 1.0000 80 chrX:12510340-12510420 1.0000 80 chrI:4967572-4967652 1.0000 80 chrV:4194927-4195007 1.0000 80 chrI:2831422-2831502 1.0000 80 chrIII:3620761-3620841 1.0000 80 chrIII:6551647-6551727 1.0000 80 chrI:4132247-4132327 1.0000 80 chrV:7820420-7820500 1.0000 80 chrIII:3175135-3175215 1.0000 80 chrV:11039745-11039825 1.0000 80 chrX:1858794-1858874 1.0000 80 chrX:13584171-13584251 1.0000 80 chrV:13396580-13396660 1.0000 80 chrI:7084465-7084545 1.0000 80 chrV:13962140-13962220 1.0000 80 chrV:1003982-1004062 1.0000 80 chrX:6220091-6220171 1.0000 80 chrV:1197376-1197456 1.0000 80 chrI:7935912-7935992 1.0000 80 chrIV:16398407-16398487 1.0000 80 chrV:53456-53536 1.0000 80 chrI:6091073-6091153 1.0000 80 chrIII:8768069-8768149 1.0000 80 chrI:10026075-10026155 1.0000 80 chrI:853292-853372 1.0000 80 chrI:11505504-11505584 1.0000 80 chrX:10435768-10435848 1.0000 80 chrIV:9191330-9191410 1.0000 80 chrII:1134544-1134624 1.0000 80 chrIII:10707204-10707284 1.0000 80 chrIII:4568702-4568782 1.0000 80 chrI:3740495-3740575 1.0000 80 chrV:13715416-13715496 1.0000 80 chrIII:10856985-10857065 1.0000 80 chrIII:11290702-11290782 1.0000 80 chrX:5812159-5812239 1.0000 80 chrV:11029477-11029557 1.0000 80 chrI:6757209-6757289 1.0000 80 chrV:16553126-16553206 1.0000 80 chrX:17315042-17315122 1.0000 80 chrIV:16382317-16382397 1.0000 80 chrII:14143968-14144048 1.0000 80 chrII:7072720-7072800 1.0000 80 chrIV:2639890-2639970 1.0000 80 chrII:8062347-8062427 1.0000 80 chrIII:3916795-3916875 1.0000 80 chrI:13331019-13331099 1.0000 80 chrX:14804857-14804937 1.0000 80 chrX:2553820-2553900 1.0000 80 chrX:4617059-4617139 1.0000 80 chrII:9566208-9566288 1.0000 80 chrIII:9104316-9104396 1.0000 80 chrV:14697046-14697126 1.0000 80 chrI:14721609-14721689 1.0000 80 chrI:27096-27176 1.0000 80 chrII:3439403-3439483 1.0000 80 chrIV:11026158-11026238 1.0000 80 chrX:2536505-2536585 1.0000 80 chrIII:8971757-8971837 1.0000 80 chrI:13310328-13310408 1.0000 80 chrIII:11317375-11317455 1.0000 80 chrX:12367732-12367812 1.0000 80 chrX:5707971-5708051 1.0000 80 chrV:6785289-6785369 1.0000 80 chrV:12780409-12780489 1.0000 80 ******************************************************************************** ******************************************************************************** COMMAND LINE SUMMARY ******************************************************************************** This information can also be useful in the event you wish to report a problem with the MEME software. command: meme -oc ../result/final_prediction/worm/inference_raw/MEME/RankLinear2.0_40_ets-7/ -dna -nmotifs 5 -w 8 -maxsize 250000 -nostatus ../result/final_prediction/worm/fasta/RankLinear2.0_40/ets-7.fasta model: mod= zoops nmotifs= 5 evt= inf objective function: em= E-value of product of p-values starts= E-value of product of p-values strands: + width: minw= 8 maxw= 8 nsites: minsites= 2 maxsites= 250 wnsites= 0.8 theta: spmap= uni spfuzz= 0.5 em: prior= dirichlet b= 0.01 maxiter= 50 distance= 1e-05 trim: wg= 11 ws= 1 endgaps= yes data: n= 20000 N= 250 sample: seed= 0 hsfrac= 0 searchsize= 20000 norand= no csites= 1000 Letter frequencies in dataset: A 0.261 C 0.228 G 0.242 T 0.269 Background letter frequencies (from file dataset with add-one prior applied): A 0.261 C 0.228 G 0.242 T 0.269 Background model order: 0 ******************************************************************************** ******************************************************************************** MOTIF CTTCCGGT MEME-1 width = 8 sites = 40 llr = 376 E-value = 3.3e-026 ******************************************************************************** -------------------------------------------------------------------------------- Motif CTTCCGGT MEME-1 Description -------------------------------------------------------------------------------- Simplified A :::::::2 pos.-specific C a::aa:11 probability G :::::a81 matrix T :aa:::17 bits 2.1 * *** 1.9 * *** 1.7 ****** 1.5 ****** Relative 1.3 ****** Entropy 1.1 ******* (13.6 bits) 0.9 ******* 0.6 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel CTTCCGGT consensus sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTTCCGGT MEME-1 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chrIII:4282719-4282799 18 1.35e-05 ACTAAAAGAA CTTCCGGT TACTGTAGAT chrV:3186513-3186593 6 1.35e-05 TTGTT CTTCCGGT TTGGCGGTCT chrX:6252874-6252954 60 1.35e-05 CCAACGCACA CTTCCGGT CATACGGTGG chrI:8230067-8230147 18 1.35e-05 TGTGCTTATC CTTCCGGT CTTTCTCTGT chrIII:8416803-8416883 9 1.35e-05 TTAGGTAA CTTCCGGT TGTTGTCCAT chrIII:12984606-12984686 59 1.35e-05 AACAAGGACA CTTCCGGT TCCAAGCTCG chrIV:12696759-12696839 49 1.35e-05 AAACTGCTCA CTTCCGGT CTTTTTATTC chrII:11464608-11464688 30 1.35e-05 CGTACCCTCT CTTCCGgt gtgtgtgtgt chrI:14921362-14921442 57 1.35e-05 AACCACCCAA CTTCCGGT TGCCACAGCT chrIII:432890-432970 43 1.35e-05 CGTGAGATAA CTTCCGGT ACTATGACAT chrII:13740977-13741057 22 1.35e-05 ttccggcaaa cttccggt ttgccggaaa chrI:7158896-7158976 39 1.35e-05 AAGCGTGTTC CTTCCGGT TGCAGGATGC chrIV:16403623-16403703 15 1.35e-05 CTCTACAGTA CTTCCGGT ATGTATCTGT chrV:14795259-14795339 52 1.35e-05 CAACTGTCCC CTTCCGGT TTACACCACC chrV:19719460-19719540 18 1.35e-05 GGGTGGAATA CTTCCGGT TTGTGCACAC chrII:11644423-11644503 38 1.35e-05 TGAAAAAACG CTTCCGGT TTCCCAAAAA chrV:7748366-7748446 8 1.35e-05 CTTCCCA CTTCCGGT ATGCCTGTCT chrI:12731445-12731525 51 1.35e-05 CAAGGATCCA CTTCCGGT TCCCGATTCG chrII:4577582-4577662 39 1.35e-05 CTCTCTCCTT CTTCCGGT CAAACCGTCT chrIII:8053590-8053670 34 1.35e-05 CGATTAGCTA CTTCCGGT CTCGCTTTTG chrII:12756339-12756419 24 1.35e-05 ATGTGGTTCA CTTCCGGT TCGCCCTTCC chrIV:3521323-3521403 48 2.66e-05 TTCTCAGTTG CTTCCGGA GCATTGGCCC chrI:8294053-8294133 42 2.66e-05 TTGCGCCATA CTTCCGGA GCTCCAGCTC chrI:7715023-7715103 56 2.66e-05 TGTTGAGCAA CTTCCGGA TTGAATTTGG chrII:7815545-7815625 62 2.66e-05 TAATACACTT CTTCCGGA GGGATTCAAC chrX:7562888-7562968 46 3.81e-05 ATGGCTCAAC CTTCCGGC CAGCAGCGCG chrIV:16407993-16408073 38 3.81e-05 CAAGGTCCTT CTTCCGGC TGTGCTAAGG chrIII:7642152-7642232 5 5.31e-05 AAAT CTTCCGTT GCGGGGAATC chrIV:11717296-11717376 63 5.31e-05 CATCTTTCTC CTTCCGTT GTCCCTCTCT chrX:16814150-16814230 25 5.31e-05 CTGCCGCCAT CTTCCGTT CTCATTAGAG chrX:10435768-10435848 30 6.58e-05 TCAGCTCAGG CTTCCGCT ACACTATTTT chrI:3861577-3861657 59 6.58e-05 ACAGTCCGTG CTTCCGCT TTGGCAAGGC chrI:13851954-13852034 2 7.80e-05 a cttccggg ctaccgtaac chrIV:9235659-9235739 45 7.80e-05 AGTACACTCA CTTCCGGG GGCAACTCCG chrV:4194927-4195007 66 1.05e-04 GATTAGCGCC CTGCCGGT GAGTGCT chrI:1271060-1271140 9 1.30e-04 TAGATCAG CATCCGGT TGTTGCTGCT chrIV:13029869-13029949 69 1.30e-04 tctacgtttt cttccgca atct chrIV:5371063-5371143 72 1.30e-04 GCGGCGCGCG CTTCCGCA A chrIII:4947434-4947514 21 1.43e-04 ATCATGTGTT CTTCCGTC TGTTTGCGCG chrV:11844965-11845045 24 1.43e-04 AACCGTCCTG CTTCCGTC CGTCCCAATG -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTTCCGGT MEME-1 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chrIII:4282719-4282799 1.4e-05 17_[+1]_55 chrV:3186513-3186593 1.4e-05 5_[+1]_67 chrX:6252874-6252954 1.4e-05 59_[+1]_13 chrI:8230067-8230147 1.4e-05 17_[+1]_55 chrIII:8416803-8416883 1.4e-05 8_[+1]_64 chrIII:12984606-12984686 1.4e-05 58_[+1]_14 chrIV:12696759-12696839 1.4e-05 48_[+1]_24 chrII:11464608-11464688 1.4e-05 29_[+1]_43 chrI:14921362-14921442 1.4e-05 56_[+1]_16 chrIII:432890-432970 1.4e-05 42_[+1]_30 chrII:13740977-13741057 1.4e-05 21_[+1]_51 chrI:7158896-7158976 1.4e-05 38_[+1]_34 chrIV:16403623-16403703 1.4e-05 14_[+1]_58 chrV:14795259-14795339 1.4e-05 51_[+1]_21 chrV:19719460-19719540 1.4e-05 17_[+1]_55 chrII:11644423-11644503 1.4e-05 37_[+1]_35 chrV:7748366-7748446 1.4e-05 7_[+1]_65 chrI:12731445-12731525 1.4e-05 50_[+1]_22 chrII:4577582-4577662 1.4e-05 38_[+1]_34 chrIII:8053590-8053670 1.4e-05 33_[+1]_39 chrII:12756339-12756419 1.4e-05 23_[+1]_49 chrIV:3521323-3521403 2.7e-05 47_[+1]_25 chrI:8294053-8294133 2.7e-05 41_[+1]_31 chrI:7715023-7715103 2.7e-05 55_[+1]_17 chrII:7815545-7815625 2.7e-05 61_[+1]_11 chrX:7562888-7562968 3.8e-05 45_[+1]_27 chrIV:16407993-16408073 3.8e-05 37_[+1]_35 chrIII:7642152-7642232 5.3e-05 4_[+1]_68 chrIV:11717296-11717376 5.3e-05 62_[+1]_10 chrX:16814150-16814230 5.3e-05 24_[+1]_48 chrX:10435768-10435848 6.6e-05 29_[+1]_43 chrI:3861577-3861657 6.6e-05 58_[+1]_14 chrI:13851954-13852034 7.8e-05 1_[+1]_71 chrIV:9235659-9235739 7.8e-05 44_[+1]_28 chrV:4194927-4195007 0.0001 65_[+1]_7 chrI:1271060-1271140 0.00013 8_[+1]_64 chrIV:13029869-13029949 0.00013 68_[+1]_4 chrIV:5371063-5371143 0.00013 71_[+1]_1 chrIII:4947434-4947514 0.00014 20_[+1]_52 chrV:11844965-11845045 0.00014 23_[+1]_49 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTTCCGGT MEME-1 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF CTTCCGGT width=8 seqs=40 chrIII:4282719-4282799 ( 18) CTTCCGGT 1 chrV:3186513-3186593 ( 6) CTTCCGGT 1 chrX:6252874-6252954 ( 60) CTTCCGGT 1 chrI:8230067-8230147 ( 18) CTTCCGGT 1 chrIII:8416803-8416883 ( 9) CTTCCGGT 1 chrIII:12984606-12984686 ( 59) CTTCCGGT 1 chrIV:12696759-12696839 ( 49) CTTCCGGT 1 chrII:11464608-11464688 ( 30) CTTCCGGT 1 chrI:14921362-14921442 ( 57) CTTCCGGT 1 chrIII:432890-432970 ( 43) CTTCCGGT 1 chrII:13740977-13741057 ( 22) CTTCCGGT 1 chrI:7158896-7158976 ( 39) CTTCCGGT 1 chrIV:16403623-16403703 ( 15) CTTCCGGT 1 chrV:14795259-14795339 ( 52) CTTCCGGT 1 chrV:19719460-19719540 ( 18) CTTCCGGT 1 chrII:11644423-11644503 ( 38) CTTCCGGT 1 chrV:7748366-7748446 ( 8) CTTCCGGT 1 chrI:12731445-12731525 ( 51) CTTCCGGT 1 chrII:4577582-4577662 ( 39) CTTCCGGT 1 chrIII:8053590-8053670 ( 34) CTTCCGGT 1 chrII:12756339-12756419 ( 24) CTTCCGGT 1 chrIV:3521323-3521403 ( 48) CTTCCGGA 1 chrI:8294053-8294133 ( 42) CTTCCGGA 1 chrI:7715023-7715103 ( 56) CTTCCGGA 1 chrII:7815545-7815625 ( 62) CTTCCGGA 1 chrX:7562888-7562968 ( 46) CTTCCGGC 1 chrIV:16407993-16408073 ( 38) CTTCCGGC 1 chrIII:7642152-7642232 ( 5) CTTCCGTT 1 chrIV:11717296-11717376 ( 63) CTTCCGTT 1 chrX:16814150-16814230 ( 25) CTTCCGTT 1 chrX:10435768-10435848 ( 30) CTTCCGCT 1 chrI:3861577-3861657 ( 59) CTTCCGCT 1 chrI:13851954-13852034 ( 2) CTTCCGGG 1 chrIV:9235659-9235739 ( 45) CTTCCGGG 1 chrV:4194927-4195007 ( 66) CTGCCGGT 1 chrI:1271060-1271140 ( 9) CATCCGGT 1 chrIV:13029869-13029949 ( 69) CTTCCGCA 1 chrIV:5371063-5371143 ( 72) CTTCCGCA 1 chrIII:4947434-4947514 ( 21) CTTCCGTC 1 chrV:11844965-11845045 ( 24) CTTCCGTC 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTTCCGGT MEME-1 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 9.08256 E= 3.3e-026 -1197 213 -1197 -1197 -338 -1197 -1197 186 -1197 -1197 -327 186 -1197 213 -1197 -1197 -1197 213 -1197 -1197 -1197 -1197 205 -1197 -1197 -119 168 -110 -80 -119 -227 138 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTTCCGGT MEME-1 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 40 E= 3.3e-026 0.000000 1.000000 0.000000 0.000000 0.025000 0.000000 0.000000 0.975000 0.000000 0.000000 0.025000 0.975000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.100000 0.775000 0.125000 0.150000 0.100000 0.050000 0.700000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTTCCGGT MEME-1 regular expression -------------------------------------------------------------------------------- CTTCCGGT -------------------------------------------------------------------------------- Time 9.24 secs. ******************************************************************************** ******************************************************************************** MOTIF ACCGGAAG MEME-2 width = 8 sites = 33 llr = 311 E-value = 4.1e-017 ******************************************************************************** -------------------------------------------------------------------------------- Motif ACCGGAAG MEME-2 Description -------------------------------------------------------------------------------- Simplified A 72:::aa2 pos.-specific C :8a::::: probability G 2::aa::8 matrix T 1::::::: bits 2.1 *** 1.9 ***** 1.7 ***** 1.5 ****** Relative 1.3 ******* Entropy 1.1 ******* (13.6 bits) 0.9 ******** 0.6 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel ACCGGAAG consensus G A sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ACCGGAAG MEME-2 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chrIII:10707204-10707284 8 1.31e-05 TCAGTGC ACCGGAAG TGCGCAAGCA chrIV:1711349-1711429 16 1.31e-05 CGGTGCCGAA ACCGGAAG AGGGAGGTGA chrI:11785644-11785724 56 1.31e-05 TCAGCTGGGA ACCGGAAG TGGTGGAAAA chrV:6053449-6053529 35 1.31e-05 ACAAACACTC ACCGGAAG GCGATGAAAT chrII:9707457-9707537 20 1.31e-05 CATTGCTCCA ACCGGAAG TACAAACTTT chrV:19720279-19720359 19 1.31e-05 GTGTGCACAA ACCGGAAG TATTCCACCC chrV:7087727-7087807 48 1.31e-05 GGCCGGTGGA ACCGGAAG TAGTCATCAT chrIII:11786090-11786170 17 1.31e-05 AAAAAGTGAG ACCGGAAG TAGAGCAACA chrX:9891920-9892000 46 1.31e-05 ATAAAACAAA ACCGGAAG TGCAAGCATA chrV:4121713-4121793 45 1.31e-05 CGTTGTTGTA ACCGGAAG TGGTTGTAGA chrII:5736010-5736090 20 1.31e-05 TCTTGATGAT ACCGGAAG TAAATCAACG chrX:1069166-1069246 68 1.31e-05 GAGCTGGAGA ACCGGAAG GAACT chrI:2011413-2011493 27 1.31e-05 GAGAGAGAGC ACCGGAAG TTCGGATGAT chrII:11644423-11644503 65 1.31e-05 AAGACCTATA ACCGGAAG TGATGCAA chrX:11128227-11128307 61 1.31e-05 TTGCAATGAG ACCGGAAG TATCAATGAG chrIII:4272814-4272894 27 3.94e-05 CCGAAATGCC ACCGGAAA TATAACTTTA chrIII:4453905-4453985 73 3.94e-05 ATATATGTCC ACCGGAAA chrV:9424643-9424723 12 3.94e-05 CGCCTGTTCC ACCGGAAA CGCGTGAAGA chrII:3956295-3956375 67 3.94e-05 GCCCAGGGGG ACCGGAAA TTGGGT chrIV:3350274-3350354 7 3.94e-05 AGTCCG GCCGGAAG CAGCAAATGT chrII:6411752-6411832 16 3.94e-05 ATGACAGAAG GCCGGAAG ATGGAGAGGA chrII:11288337-11288417 28 3.94e-05 AATGTAACTA GCCGGAAG GAGATCCCCC chrIII:2780401-2780481 55 3.94e-05 GCGTTCAGGG GCCGGAAG GAATAGTTGA chrIV:14032865-14032945 33 5.44e-05 CCGTATAGAC AACGGAAG AGGGTGAACA chrX:14486744-14486824 33 5.44e-05 Taagaagaag aacggaag aagatgagga chrI:2826884-2826964 29 6.79e-05 CCAATCATGT TCCGGAAG CAATTAGAGC chrIV:10868952-10869032 64 6.79e-05 GCAATAGGGC TCCGGAAG TCGATTCCT chrII:8897396-8897476 49 6.79e-05 ATCTTACCGG TCCGGAAG TGCACATTTC chrX:2707856-2707936 44 8.10e-05 GTTATGAATA GCCGGAAA ATGTGATAAT chrII:13740977-13741057 32 8.10e-05 cttccggttt gccggaaa ctttgatttt chrII:7072720-7072800 23 1.11e-04 TTAATGAGGA AACGGAAA ACGGAGGAAA chrI:9564397-9564477 57 1.11e-04 AAAGGACAAG GACGGAAG GATAAAAGAA chrI:7715687-7715767 56 1.11e-04 AGGAGGTGTC AACGGAAA AACGAAGGCA -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ACCGGAAG MEME-2 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chrIII:10707204-10707284 1.3e-05 7_[+2]_65 chrIV:1711349-1711429 1.3e-05 15_[+2]_57 chrI:11785644-11785724 1.3e-05 55_[+2]_17 chrV:6053449-6053529 1.3e-05 34_[+2]_38 chrII:9707457-9707537 1.3e-05 19_[+2]_53 chrV:19720279-19720359 1.3e-05 18_[+2]_54 chrV:7087727-7087807 1.3e-05 47_[+2]_25 chrIII:11786090-11786170 1.3e-05 16_[+2]_56 chrX:9891920-9892000 1.3e-05 45_[+2]_27 chrV:4121713-4121793 1.3e-05 44_[+2]_28 chrII:5736010-5736090 1.3e-05 19_[+2]_53 chrX:1069166-1069246 1.3e-05 67_[+2]_5 chrI:2011413-2011493 1.3e-05 26_[+2]_46 chrII:11644423-11644503 1.3e-05 64_[+2]_8 chrX:11128227-11128307 1.3e-05 60_[+2]_12 chrIII:4272814-4272894 3.9e-05 26_[+2]_46 chrIII:4453905-4453985 3.9e-05 72_[+2] chrV:9424643-9424723 3.9e-05 11_[+2]_61 chrII:3956295-3956375 3.9e-05 66_[+2]_6 chrIV:3350274-3350354 3.9e-05 6_[+2]_66 chrII:6411752-6411832 3.9e-05 15_[+2]_57 chrII:11288337-11288417 3.9e-05 27_[+2]_45 chrIII:2780401-2780481 3.9e-05 54_[+2]_18 chrIV:14032865-14032945 5.4e-05 32_[+2]_40 chrX:14486744-14486824 5.4e-05 32_[+2]_40 chrI:2826884-2826964 6.8e-05 28_[+2]_44 chrIV:10868952-10869032 6.8e-05 63_[+2]_9 chrII:8897396-8897476 6.8e-05 48_[+2]_24 chrX:2707856-2707936 8.1e-05 43_[+2]_29 chrII:13740977-13741057 8.1e-05 31_[+2]_41 chrII:7072720-7072800 0.00011 22_[+2]_50 chrI:9564397-9564477 0.00011 56_[+2]_16 chrI:7715687-7715767 0.00011 55_[+2]_17 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ACCGGAAG MEME-2 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF ACCGGAAG width=8 seqs=33 chrIII:10707204-10707284 ( 8) ACCGGAAG 1 chrIV:1711349-1711429 ( 16) ACCGGAAG 1 chrI:11785644-11785724 ( 56) ACCGGAAG 1 chrV:6053449-6053529 ( 35) ACCGGAAG 1 chrII:9707457-9707537 ( 20) ACCGGAAG 1 chrV:19720279-19720359 ( 19) ACCGGAAG 1 chrV:7087727-7087807 ( 48) ACCGGAAG 1 chrIII:11786090-11786170 ( 17) ACCGGAAG 1 chrX:9891920-9892000 ( 46) ACCGGAAG 1 chrV:4121713-4121793 ( 45) ACCGGAAG 1 chrII:5736010-5736090 ( 20) ACCGGAAG 1 chrX:1069166-1069246 ( 68) ACCGGAAG 1 chrI:2011413-2011493 ( 27) ACCGGAAG 1 chrII:11644423-11644503 ( 65) ACCGGAAG 1 chrX:11128227-11128307 ( 61) ACCGGAAG 1 chrIII:4272814-4272894 ( 27) ACCGGAAA 1 chrIII:4453905-4453985 ( 73) ACCGGAAA 1 chrV:9424643-9424723 ( 12) ACCGGAAA 1 chrII:3956295-3956375 ( 67) ACCGGAAA 1 chrIV:3350274-3350354 ( 7) GCCGGAAG 1 chrII:6411752-6411832 ( 16) GCCGGAAG 1 chrII:11288337-11288417 ( 28) GCCGGAAG 1 chrIII:2780401-2780481 ( 55) GCCGGAAG 1 chrIV:14032865-14032945 ( 33) AACGGAAG 1 chrX:14486744-14486824 ( 33) AACGGAAG 1 chrI:2826884-2826964 ( 29) TCCGGAAG 1 chrIV:10868952-10869032 ( 64) TCCGGAAG 1 chrII:8897396-8897476 ( 49) TCCGGAAG 1 chrX:2707856-2707936 ( 44) GCCGGAAA 1 chrII:13740977-13741057 ( 32) GCCGGAAA 1 chrII:7072720-7072800 ( 23) AACGGAAA 1 chrI:9564397-9564477 ( 57) GACGGAAG 1 chrI:7715687-7715767 ( 56) AACGGAAA 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ACCGGAAG MEME-2 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 9.87609 E= 4.1e-017 142 -1169 -19 -156 -78 190 -1169 -1169 -1169 213 -1169 -1169 -1169 -1169 205 -1169 -1169 -1169 205 -1169 194 -1169 -1169 -1169 194 -1169 -1169 -1169 -11 -1169 164 -1169 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ACCGGAAG MEME-2 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 33 E= 4.1e-017 0.696970 0.000000 0.212121 0.090909 0.151515 0.848485 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.242424 0.000000 0.757576 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ACCGGAAG MEME-2 regular expression -------------------------------------------------------------------------------- [AG]CCGGAA[GA] -------------------------------------------------------------------------------- Time 12.96 secs. ******************************************************************************** ******************************************************************************** MOTIF GCGCGCGC MEME-3 width = 8 sites = 17 llr = 164 E-value = 4.0e-001 ******************************************************************************** -------------------------------------------------------------------------------- Motif GCGCGCGC MEME-3 Description -------------------------------------------------------------------------------- Simplified A :1::1::: pos.-specific C 191a1a:9 probability G 9:9:9:91 matrix T 1:::::1: bits 2.1 * * 1.9 * * 1.7 ** *** 1.5 ******** Relative 1.3 ******** Entropy 1.1 ******** (13.9 bits) 0.9 ******** 0.6 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel GCGCGCGC consensus sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GCGCGCGC MEME-3 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chrI:14721609-14721689 12 9.27e-06 TTTGCAATGC GCGCGCGC GGTTTTCGCA chrIII:3916795-3916875 37 9.27e-06 TGCAAACACT GCGCGCGC AGCTTGCAAG chrII:7708749-7708829 5 9.27e-06 CAAT GCGCGCGC ACGGTTTTTG chrII:11537320-11537400 27 9.27e-06 TGCTGTGAGC GCGCGCGC GCGAGCGCAC chrIII:4947434-4947514 36 9.27e-06 GTCTGTTTGC GCGCGCGC GCCTCGCCTC chrI:4032662-4032742 27 9.27e-06 AAGGGTCACT GCGCGCGC AGACGGATGT chrI:13851954-13852034 51 9.27e-06 atgtgtgcgc gcgcgcgc gtggggagag chrIV:16407993-16408073 15 9.27e-06 ATCGGTGTGC GCGCGCGC GCTCACAAGG chrII:476194-476274 12 1.99e-05 GCGTGCGGTA GAGCGCGC TTGCCGACGA chrX:16814150-16814230 40 1.99e-05 GTTCTCATTA GAGCGCGC TTGCTGTACA chrIII:11290702-11290782 63 3.73e-05 GTCCCGGGTC GCGCCCGC GAATTCTTCG chrIII:3664385-3664465 36 3.73e-05 TTGCAACACG CCGCGCGC ATTTCGCAAC chrV:13962140-13962220 66 6.59e-05 TGCATAAACT GCGCGCGG CAACTGC chrX:7478578-7478658 9 6.59e-05 AGGGGGGT GCGCACGC GGTCGCGTCG chrV:14795259-14795339 35 6.59e-05 GCGACGTGCC GCCCGCGC AACTGTCCCC chrIII:1824681-1824761 39 7.62e-05 TCTTGCAAAA TCGCGCGC CGCAGGCTGC chrI:2487823-2487903 66 8.65e-05 GTGTCAGCAA GCGCGCTC CAATGAT -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GCGCGCGC MEME-3 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chrI:14721609-14721689 9.3e-06 11_[+3]_61 chrIII:3916795-3916875 9.3e-06 36_[+3]_36 chrII:7708749-7708829 9.3e-06 4_[+3]_68 chrII:11537320-11537400 9.3e-06 26_[+3]_46 chrIII:4947434-4947514 9.3e-06 35_[+3]_37 chrI:4032662-4032742 9.3e-06 26_[+3]_46 chrI:13851954-13852034 9.3e-06 50_[+3]_22 chrIV:16407993-16408073 9.3e-06 14_[+3]_58 chrII:476194-476274 2e-05 11_[+3]_61 chrX:16814150-16814230 2e-05 39_[+3]_33 chrIII:11290702-11290782 3.7e-05 62_[+3]_10 chrIII:3664385-3664465 3.7e-05 35_[+3]_37 chrV:13962140-13962220 6.6e-05 65_[+3]_7 chrX:7478578-7478658 6.6e-05 8_[+3]_64 chrV:14795259-14795339 6.6e-05 34_[+3]_38 chrIII:1824681-1824761 7.6e-05 38_[+3]_34 chrI:2487823-2487903 8.7e-05 65_[+3]_7 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GCGCGCGC MEME-3 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF GCGCGCGC width=8 seqs=17 chrI:14721609-14721689 ( 12) GCGCGCGC 1 chrIII:3916795-3916875 ( 37) GCGCGCGC 1 chrII:7708749-7708829 ( 5) GCGCGCGC 1 chrII:11537320-11537400 ( 27) GCGCGCGC 1 chrIII:4947434-4947514 ( 36) GCGCGCGC 1 chrI:4032662-4032742 ( 27) GCGCGCGC 1 chrI:13851954-13852034 ( 51) GCGCGCGC 1 chrIV:16407993-16408073 ( 15) GCGCGCGC 1 chrII:476194-476274 ( 12) GAGCGCGC 1 chrX:16814150-16814230 ( 40) GAGCGCGC 1 chrIII:11290702-11290782 ( 63) GCGCCCGC 1 chrIII:3664385-3664465 ( 36) CCGCGCGC 1 chrV:13962140-13962220 ( 66) GCGCGCGG 1 chrX:7478578-7478658 ( 9) GCGCACGC 1 chrV:14795259-14795339 ( 35) GCCCGCGC 1 chrIII:1824681-1824761 ( 39) TCGCGCGC 1 chrI:2487823-2487903 ( 66) GCGCGCTC 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GCGCGCGC MEME-3 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 11.8333 E= 4.0e-001 -1073 -195 186 -219 -115 195 -1073 -1073 -1073 -195 196 -1073 -1073 213 -1073 -1073 -215 -195 186 -1073 -1073 213 -1073 -1073 -1073 -1073 196 -219 -1073 204 -204 -1073 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GCGCGCGC MEME-3 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 17 E= 4.0e-001 0.000000 0.058824 0.882353 0.058824 0.117647 0.882353 0.000000 0.000000 0.000000 0.058824 0.941176 0.000000 0.000000 1.000000 0.000000 0.000000 0.058824 0.058824 0.882353 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.941176 0.058824 0.000000 0.941176 0.058824 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GCGCGCGC MEME-3 regular expression -------------------------------------------------------------------------------- GCGCGCGC -------------------------------------------------------------------------------- Time 16.56 secs. ******************************************************************************** ******************************************************************************** MOTIF CCKCCCAC MEME-4 width = 8 sites = 8 llr = 87 E-value = 1.7e+002 ******************************************************************************** -------------------------------------------------------------------------------- Motif CCKCCCAC MEME-4 Description -------------------------------------------------------------------------------- Simplified A ::::::a: pos.-specific C aa:aaa:a probability G ::6::::: matrix T ::4::::: bits 2.1 ** *** * 1.9 ** ***** 1.7 ** ***** 1.5 ** ***** Relative 1.3 ** ***** Entropy 1.1 ******** (15.8 bits) 0.9 ******** 0.6 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel CCGCCCAC consensus T sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCKCCCAC MEME-4 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chrIII:8768069-8768149 70 8.87e-06 CGATTCAACT CCGCCCAC AAA chrIV:1981093-1981173 63 8.87e-06 GTGCGGCTCC CCGCCCAC TTTTCCGTGC chrIII:4282719-4282799 2 8.87e-06 T CCGCCCAC TAAAAGAACT chrIV:9316214-9316294 63 8.87e-06 GTCATCATCC CCGCCCAC TTTTATTCGT chrIV:9235659-9235739 60 8.87e-06 GGGGGCAACT CCGCCCAC AATTACTGGG chrX:14115626-14115706 51 1.87e-05 CAAACGACCT CCTCCCAC TTTCGTGGCC chrX:14027024-14027104 9 1.87e-05 TTTTCTGG CCTCCCAC CATGCGAATG chrI:7715687-7715767 26 1.87e-05 TGCCAACCCT CCTCCCAC AAGCAGATCT -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCKCCCAC MEME-4 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chrIII:8768069-8768149 8.9e-06 69_[+4]_3 chrIV:1981093-1981173 8.9e-06 62_[+4]_10 chrIII:4282719-4282799 8.9e-06 1_[+4]_71 chrIV:9316214-9316294 8.9e-06 62_[+4]_10 chrIV:9235659-9235739 8.9e-06 59_[+4]_13 chrX:14115626-14115706 1.9e-05 50_[+4]_22 chrX:14027024-14027104 1.9e-05 8_[+4]_64 chrI:7715687-7715767 1.9e-05 25_[+4]_47 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCKCCCAC MEME-4 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF CCKCCCAC width=8 seqs=8 chrIII:8768069-8768149 ( 70) CCGCCCAC 1 chrIV:1981093-1981173 ( 63) CCGCCCAC 1 chrIII:4282719-4282799 ( 2) CCGCCCAC 1 chrIV:9316214-9316294 ( 63) CCGCCCAC 1 chrIV:9235659-9235739 ( 60) CCGCCCAC 1 chrX:14115626-14115706 ( 51) CCTCCCAC 1 chrX:14027024-14027104 ( 9) CCTCCCAC 1 chrI:7715687-7715767 ( 26) CCTCCCAC 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCKCCCAC MEME-4 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 11.8922 E= 1.7e+002 -965 213 -965 -965 -965 213 -965 -965 -965 -965 137 48 -965 213 -965 -965 -965 213 -965 -965 -965 213 -965 -965 194 -965 -965 -965 -965 213 -965 -965 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCKCCCAC MEME-4 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 8 E= 1.7e+002 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.625000 0.375000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCKCCCAC MEME-4 regular expression -------------------------------------------------------------------------------- CC[GT]CCCAC -------------------------------------------------------------------------------- Time 20.12 secs. ******************************************************************************** ******************************************************************************** MOTIF CGTGCGGC MEME-5 width = 8 sites = 18 llr = 167 E-value = 2.6e+002 ******************************************************************************** -------------------------------------------------------------------------------- Motif CGTGCGGC MEME-5 Description -------------------------------------------------------------------------------- Simplified A ::1::::: pos.-specific C 7:::8::8 probability G :a:a1aa: matrix T 3:9:1::2 bits 2.1 * * ** 1.9 * * ** 1.7 * * ** 1.5 *** *** Relative 1.3 **** *** Entropy 1.1 ******** (13.3 bits) 0.9 ******** 0.6 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel CGTGCGGC consensus T sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CGTGCGGC MEME-5 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chrIII:4568702-4568782 45 1.09e-05 GCGAGAAACA CGTGCGGC GCTTGCAAAT chrI:7935912-7935992 69 1.09e-05 GTTTTAAAAC CGTGCGGC AGTT chrIV:1981093-1981173 52 1.09e-05 GGCGGGCTTG CGTGCGGC TCCCCGCCCA chrIII:1824681-1824761 19 1.09e-05 AACTAAACCC CGTGCGGC GCTCTTGCAA chrIV:9316214-9316294 7 1.09e-05 TAAAAC CGTGCGGC GGAATTGCGA chrIV:5371063-5371143 17 1.09e-05 AAAATAAAAC CGTGCGGC AACATTGCGA chrIII:3916795-3916875 14 2.38e-05 ACCTAAAGTG TGTGCGGC GACTTTGCAA chrIII:8768069-8768149 13 2.38e-05 CTGAGTAAAC TGTGCGGC GTGTTTGCGG chrIII:3175135-3175215 25 2.38e-05 CTCTTAACTC TGTGCGGC ACCATTGCGG chrV:13715416-13715496 23 3.67e-05 TCATTTAATG CGTGCGGT AGAGCGCGGT chrII:476194-476274 3 3.67e-05 GG CGTGCGGT AGAGCGCGCT chrV:16553126-16553206 43 4.83e-05 ATCCCCTTTT CGTGGGGC CTCGTCAAAT chrIII:3499993-3500073 18 4.83e-05 TTCCCGCTTT CGTGGGGC CTCAAACCCG chrX:5707971-5708051 12 7.19e-05 GGAGCGGCCG CGTGTGGC GAGTATAACT chrX:14115626-14115706 68 7.19e-05 CTTTCGTGGC CGTGTGGC CTAAT chrX:5205689-5205769 46 7.19e-05 GGCGAGAGAG CGAGCGGC CGTGGCCTAG chrX:3348023-3348103 42 8.71e-05 TGAGTGGTAG TGTGCGGT ACTTCGGTCC chrII:8128873-8128953 19 1.29e-04 CCCAGGCTGT TGAGCGGC GGCGGCGACG -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CGTGCGGC MEME-5 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chrIII:4568702-4568782 1.1e-05 44_[+5]_28 chrI:7935912-7935992 1.1e-05 68_[+5]_4 chrIV:1981093-1981173 1.1e-05 51_[+5]_21 chrIII:1824681-1824761 1.1e-05 18_[+5]_54 chrIV:9316214-9316294 1.1e-05 6_[+5]_66 chrIV:5371063-5371143 1.1e-05 16_[+5]_56 chrIII:3916795-3916875 2.4e-05 13_[+5]_59 chrIII:8768069-8768149 2.4e-05 12_[+5]_60 chrIII:3175135-3175215 2.4e-05 24_[+5]_48 chrV:13715416-13715496 3.7e-05 22_[+5]_50 chrII:476194-476274 3.7e-05 2_[+5]_70 chrV:16553126-16553206 4.8e-05 42_[+5]_30 chrIII:3499993-3500073 4.8e-05 17_[+5]_55 chrX:5707971-5708051 7.2e-05 11_[+5]_61 chrX:14115626-14115706 7.2e-05 67_[+5]_5 chrX:5205689-5205769 7.2e-05 45_[+5]_27 chrX:3348023-3348103 8.7e-05 41_[+5]_31 chrII:8128873-8128953 0.00013 18_[+5]_54 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CGTGCGGC MEME-5 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF CGTGCGGC width=8 seqs=18 chrIII:4568702-4568782 ( 45) CGTGCGGC 1 chrI:7935912-7935992 ( 69) CGTGCGGC 1 chrIV:1981093-1981173 ( 52) CGTGCGGC 1 chrIII:1824681-1824761 ( 19) CGTGCGGC 1 chrIV:9316214-9316294 ( 7) CGTGCGGC 1 chrIV:5371063-5371143 ( 17) CGTGCGGC 1 chrIII:3916795-3916875 ( 14) TGTGCGGC 1 chrIII:8768069-8768149 ( 13) TGTGCGGC 1 chrIII:3175135-3175215 ( 25) TGTGCGGC 1 chrV:13715416-13715496 ( 23) CGTGCGGT 1 chrII:476194-476274 ( 3) CGTGCGGT 1 chrV:16553126-16553206 ( 43) CGTGGGGC 1 chrIII:3499993-3500073 ( 18) CGTGGGGC 1 chrX:5707971-5708051 ( 12) CGTGTGGC 1 chrX:14115626-14115706 ( 68) CGTGTGGC 1 chrX:5205689-5205769 ( 46) CGAGCGGC 1 chrX:3348023-3348103 ( 42) TGTGCGGT 1 chrII:8128873-8128953 ( 19) TGAGCGGC 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CGTGCGGC MEME-5 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 10.8329 E= 2.6e+002 -1081 166 -1081 5 -1081 -1081 205 -1081 -123 -1081 -1081 173 -1081 -1081 205 -1081 -1081 177 -112 -127 -1081 -1081 205 -1081 -1081 -1081 205 -1081 -1081 187 -1081 -69 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CGTGCGGC MEME-5 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 18 E= 2.6e+002 0.000000 0.722222 0.000000 0.277778 0.000000 0.000000 1.000000 0.000000 0.111111 0.000000 0.000000 0.888889 0.000000 0.000000 1.000000 0.000000 0.000000 0.777778 0.111111 0.111111 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.833333 0.000000 0.166667 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CGTGCGGC MEME-5 regular expression -------------------------------------------------------------------------------- [CT]GTGCGGC -------------------------------------------------------------------------------- Time 23.68 secs. ******************************************************************************** ******************************************************************************** SUMMARY OF MOTIFS ******************************************************************************** -------------------------------------------------------------------------------- Combined block diagrams: non-overlapping sites with p-value < 0.0001 -------------------------------------------------------------------------------- SEQUENCE NAME COMBINED P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chrII:12756339-12756419 2.88e-02 23_[+1(1.35e-05)]_49 chrIII:8053590-8053670 8.52e-02 33_[+1(1.35e-05)]_39 chrIII:8298358-8298438 6.36e-01 80 chrII:4577582-4577662 1.93e-02 38_[+1(1.35e-05)]_34 chrI:12731445-12731525 4.04e-02 50_[+1(1.35e-05)]_22 chrX:11128227-11128307 2.88e-02 60_[+2(1.31e-05)]_12 chrV:7748366-7748446 1.90e-03 7_[+1(1.35e-05)]_65 chrII:11644423-11644503 1.18e-03 37_[+1(1.35e-05)]_19_[+2(1.31e-05)]_\ 8 chrI:2011413-2011493 7.34e-02 26_[+2(1.31e-05)]_46 chrX:1069166-1069246 2.93e-03 67_[+2(1.31e-05)]_5 chrV:19719460-19719540 1.30e-03 17_[+1(1.35e-05)]_55 chrII:5736010-5736090 3.44e-02 19_[+2(1.31e-05)]_53 chrII:7815545-7815625 9.30e-03 61_[+1(2.66e-05)]_11 chrI:7715023-7715103 1.60e-01 55_[+1(2.66e-05)]_17 chrX:16814150-16814230 1.50e-04 24_[+1(5.31e-05)]_7_[+3(1.99e-05)]_\ 33 chrIII:2780401-2780481 4.01e-02 54_[+2(3.94e-05)]_18 chrII:11288337-11288417 2.65e-03 27_[+2(3.94e-05)]_45 chrM:5149-5229 1.00e+00 80 chrV:14795259-14795339 7.91e-07 32_[+4(6.18e-05)]_11_[+1(1.35e-05)]_\ 21 chrII:6411752-6411832 5.39e-02 15_[+2(3.94e-05)]_57 chrII:8897396-8897476 1.77e-02 48_[+2(6.79e-05)]_24 chrV:4121713-4121793 1.21e-02 44_[+2(1.31e-05)]_28 chrIV:16407993-16408073 3.51e-04 12_[+3(9.27e-06)]_17_[+1(3.81e-05)]_\ 35 chrX:14486744-14486824 2.78e-01 32_[+2(5.44e-05)]_40 chrII:6844649-6844729 7.43e-01 80 chrM:1752-1832 1.00e+00 80 chrI:8294053-8294133 2.45e-02 41_[+1(2.66e-05)]_31 chrM:10030-10110 1.00e+00 80 chrM:3252-3332 9.98e-01 80 chrI:933477-933557 2.93e-01 80 chrIV:3350274-3350354 1.14e-02 6_[+2(3.94e-05)]_66 chrX:11870605-11870685 9.57e-01 80 chrIII:3499993-3500073 1.67e-03 17_[+5(4.83e-05)]_55 chrIII:931564-931644 9.95e-01 80 chrIV:16403623-16403703 5.97e-02 14_[+1(1.35e-05)]_58 chrX:15264766-15264846 3.43e-01 80 chrM:2987-3067 7.94e-01 80 chrIV:385238-385318 9.12e-01 80 chrI:7158896-7158976 1.54e-02 38_[+1(1.35e-05)]_34 chrII:13740977-13741057 4.10e-03 21_[+1(1.35e-05)]_2_[+2(8.10e-05)]_\ 27_[+2(8.10e-05)]_6 chrI:8783739-8783819 6.02e-01 80 chrIV:10868952-10869032 2.04e-01 63_[+2(6.79e-05)]_9 chrIII:432890-432970 2.54e-02 42_[+1(1.35e-05)]_30 chrI:7715687-7715767 6.91e-03 25_[+4(1.87e-05)]_47 chrIII:2532797-2532877 5.09e-02 80 chrX:7478578-7478658 1.39e-01 8_[+3(6.59e-05)]_64 chrII:3956295-3956375 2.67e-02 66_[+2(3.94e-05)]_6 chrX:9891920-9892000 1.03e-01 45_[+2(1.31e-05)]_27 chrM:8247-8327 2.48e-01 80 chrI:2826884-2826964 1.08e-03 28_[+2(6.79e-05)]_44 chrII:3880687-3880767 4.99e-01 80 chrIII:11786090-11786170 5.52e-02 16_[+2(1.31e-05)]_56 chrIV:5371063-5371143 1.01e-05 16_[+5(1.09e-05)]_40_[+3(9.27e-06)]_\ 8 chrIV:3521323-3521403 5.77e-02 1_[+1(7.80e-05)]_38_[+1(2.66e-05)]_\ 25 chrX:5056378-5056458 2.90e-01 80 chrIV:9048255-9048335 9.98e-01 80 chrI:11609236-11609316 9.55e-02 80 chrI:14921362-14921442 9.05e-03 56_[+1(1.35e-05)]_16 chrM:7082-7162 9.87e-01 80 chrV:9424643-9424723 2.79e-02 11_[+2(3.94e-05)]_61 chrII:9308993-9309073 6.36e-01 80 chrI:10469192-10469272 6.21e-01 80 chrM:7284-7364 8.27e-01 80 chrX:7562888-7562968 2.08e-03 45_[+1(3.81e-05)]_27 chrII:11464608-11464688 2.45e-02 29_[+1(1.35e-05)]_43 chrIV:9235659-9235739 8.19e-04 44_[+1(7.80e-05)]_7_[+4(8.87e-06)]_\ 13 chrV:7087727-7087807 3.02e-02 47_[+2(1.31e-05)]_25 chrI:9564397-9564477 4.13e-01 80 chrIV:12696759-12696839 2.54e-02 48_[+1(1.35e-05)]_24 chrIII:4453905-4453985 1.55e-02 72_[+2(3.94e-05)] chrI:11095869-11095949 5.93e-01 80 chrIV:13029869-13029949 3.55e-02 80 chrIII:12984606-12984686 8.20e-02 58_[+1(1.35e-05)]_14 chrV:19720279-19720359 1.43e-02 18_[+2(1.31e-05)]_54 chrV:11844965-11845045 4.88e-02 80 chrIII:8416803-8416883 9.70e-02 8_[+1(1.35e-05)]_64 chrM:1049-1129 1.00e+00 80 chrI:13851954-13852034 8.17e-05 1_[+1(7.80e-05)]_37_[+3(9.27e-06)]_\ 26 chrX:2707856-2707936 1.01e-01 43_[+2(8.10e-05)]_29 chrIV:9316214-9316294 9.94e-05 6_[+5(1.09e-05)]_48_[+4(8.87e-06)]_\ 10 chrI:8230067-8230147 8.90e-02 17_[+1(1.35e-05)]_13_[+1(6.58e-05)]_\ 34 chrII:9707457-9707537 3.14e-02 19_[+2(1.31e-05)]_53 chrM:9063-9143 9.83e-01 80 chrI:4032662-4032742 8.46e-03 26_[+3(9.27e-06)]_46 chrX:10435559-10435639 7.67e-01 80 chrIII:4947434-4947514 1.75e-03 33_[+3(9.27e-06)]_39 chrIV:11717296-11717376 1.13e-01 62_[+1(5.31e-05)]_10 chrX:13007968-13008048 9.57e-01 80 chrX:3738747-3738827 5.68e-01 80 chrM:4599-4679 9.62e-01 80 chrIII:11091831-11091911 2.37e-01 80 chrI:4175996-4176076 8.44e-01 80 chrM:6281-6361 4.15e-01 80 chrII:6741574-6741654 8.09e-01 80 chrI:3842581-3842661 3.70e-01 80 chrI:12225396-12225476 9.06e-02 80 chrX:14691347-14691427 5.76e-01 80 chrIV:560370-560450 2.44e-01 80 chrX:14027024-14027104 2.19e-02 8_[+4(1.87e-05)]_43_[+4(3.67e-05)]_\ 13 chrM:6079-6159 9.68e-01 80 chrIV:6887831-6887911 3.13e-01 80 chrV:6053449-6053529 7.77e-03 34_[+2(1.31e-05)]_38 chrX:6252874-6252954 2.21e-02 59_[+1(1.35e-05)]_13 chrX:5205689-5205769 6.04e-02 45_[+5(7.19e-05)]_27 chrV:6223846-6223926 5.84e-01 80 chrM:10232-10312 9.54e-01 80 chrII:3374089-3374169 7.53e-01 80 chrIII:4905440-4905520 2.38e-01 80 chrM:8453-8533 6.56e-01 80 chrIII:1824681-1824761 3.68e-04 18_[+5(1.09e-05)]_12_[+3(7.62e-05)]_\ 34 chrI:11765970-11766050 9.62e-01 80 chrI:7217535-7217615 5.69e-01 80 chrM:3556-3636 9.99e-01 80 chrV:3186513-3186593 1.24e-03 5_[+1(1.35e-05)]_67 chrII:12042349-12042429 6.10e-01 80 chrM:2120-2200 2.66e-01 80 chrI:11785644-11785724 1.32e-02 55_[+2(1.31e-05)]_17 chrIII:4272814-4272894 1.52e-01 26_[+2(3.94e-05)]_46 chrII:11537320-11537400 4.03e-03 24_[+3(9.27e-06)]_48 chrV:5284758-5284838 8.90e-01 80 chrIV:1711349-1711429 3.27e-02 15_[+2(1.31e-05)]_57 chrII:14406922-14407002 9.97e-01 80 chrIII:8650407-8650487 2.43e-03 80 chrIII:11848517-11848597 4.99e-01 80 chrII:476194-476274 5.58e-04 2_[+5(3.67e-05)]_1_[+3(1.99e-05)]_\ 61 chrIII:4280929-4281009 9.10e-01 80 chrIV:565533-565613 4.62e-01 80 chrII:5836521-5836601 9.66e-01 80 chrIII:3476377-3476457 9.99e-01 80 chrII:7708749-7708829 6.05e-03 4_[+3(9.27e-06)]_68 chrIV:11639194-11639274 8.23e-01 80 chrI:1271060-1271140 1.50e-03 80 chrI:2487823-2487903 2.39e-02 65_[+3(8.65e-05)]_7 chrI:1416037-1416117 1.00e+00 80 chrII:11884364-11884444 1.58e-01 80 chrI:9448087-9448167 9.66e-01 80 chrII:11534671-11534751 9.06e-01 80 chrX:8156103-8156183 8.34e-01 80 chrX:3994557-3994637 3.05e-01 80 chrII:8927402-8927482 8.48e-01 80 chrII:8128873-8128953 1.32e-01 80 chrI:3861577-3861657 1.07e-02 58_[+1(6.58e-05)]_14 chrI:7251637-7251717 3.15e-01 80 chrIII:4282719-4282799 1.04e-04 1_[+4(8.87e-06)]_8_[+1(1.35e-05)]_\ 55 chrM:12383-12463 1.00e+00 80 chrII:66372-66452 2.06e-01 80 chrII:6831838-6831918 3.06e-01 80 chrX:12890273-12890353 1.13e-01 80 chrX:14115626-14115706 1.60e-03 50_[+4(1.87e-05)]_9_[+5(7.19e-05)]_\ 5 chrIV:16995567-16995647 2.02e-01 80 chrV:14688718-14688798 7.00e-01 80 chrIII:8144742-8144822 3.77e-01 80 chrX:8386201-8386281 1.48e-01 80 chrIV:16401096-16401176 8.68e-01 80 chrIII:6537365-6537445 1.18e-01 80 chrI:9268937-9269017 1.86e-01 80 chrIV:14032865-14032945 7.42e-02 32_[+2(5.44e-05)]_40 chrIV:8016136-8016216 9.65e-01 80 chrX:3348023-3348103 1.70e-02 41_[+5(8.71e-05)]_31 chrII:14528379-14528459 4.78e-01 80 chrIII:3664385-3664465 2.96e-03 35_[+3(3.73e-05)]_37 chrI:7772627-7772707 9.03e-01 80 chrI:10642461-10642541 3.33e-01 80 chrX:16928320-16928400 4.61e-01 80 chrII:13291583-13291663 5.40e-01 80 chrIII:7642152-7642232 1.20e-01 4_[+1(5.31e-05)]_68 chrII:5594377-5594457 3.73e-02 80 chrIII:9700418-9700498 4.87e-01 80 chrIV:3233006-3233086 2.43e-02 80 chrV:4181911-4181991 2.85e-01 80 chrIII:1122414-1122494 2.16e-01 80 chrII:6565204-6565284 1.06e-01 80 chrM:12582-12662 9.99e-01 80 chrIV:9216709-9216789 2.03e-01 80 chrII:7001584-7001664 1.15e-01 80 chrII:15232900-15232980 6.83e-01 80 chrI:1823232-1823312 1.22e-01 80 chrX:9337942-9338022 2.11e-01 80 chrI:3176586-3176666 2.75e-01 80 chrIV:1981093-1981173 7.53e-05 51_[+5(1.09e-05)]_3_[+4(8.87e-06)]_\ 10 chrII:6248644-6248724 4.79e-01 80 chrII:9263157-9263237 2.73e-01 80 chrII:5966763-5966843 3.90e-01 80 chrII:14249578-14249658 5.71e-02 80 chrX:9225546-9225626 2.34e-01 80 chrX:12510340-12510420 2.52e-02 80 chrI:4967572-4967652 9.91e-01 80 chrV:4194927-4195007 3.77e-03 80 chrI:2831422-2831502 8.84e-01 80 chrIII:3620761-3620841 4.94e-01 80 chrIII:6551647-6551727 7.96e-01 80 chrI:4132247-4132327 3.54e-01 80 chrV:7820420-7820500 6.49e-02 80 chrIII:3175135-3175215 4.14e-02 24_[+5(2.38e-05)]_48 chrV:11039745-11039825 9.15e-01 80 chrX:1858794-1858874 2.90e-02 80 chrX:13584171-13584251 2.54e-01 80 chrV:13396580-13396660 4.18e-01 80 chrI:7084465-7084545 8.29e-01 80 chrV:13962140-13962220 4.84e-03 65_[+3(6.59e-05)]_7 chrV:1003982-1004062 1.00e+00 80 chrX:6220091-6220171 2.24e-01 80 chrV:1197376-1197456 8.57e-01 80 chrI:7935912-7935992 4.62e-03 68_[+5(1.09e-05)]_4 chrIV:16398407-16398487 8.55e-01 80 chrV:53456-53536 2.67e-01 80 chrI:6091073-6091153 4.96e-01 80 chrIII:8768069-8768149 9.74e-05 12_[+5(2.38e-05)]_49_[+4(8.87e-06)]_\ 3 chrI:10026075-10026155 9.98e-02 80 chrI:853292-853372 4.20e-01 80 chrI:11505504-11505584 2.93e-01 80 chrX:10435768-10435848 1.07e-01 29_[+1(6.58e-05)]_43 chrIV:9191330-9191410 1.89e-01 80 chrII:1134544-1134624 9.48e-01 80 chrIII:10707204-10707284 1.66e-03 7_[+2(1.31e-05)]_65 chrIII:4568702-4568782 3.60e-03 44_[+5(1.09e-05)]_28 chrI:3740495-3740575 1.74e-01 80 chrV:13715416-13715496 4.10e-03 22_[+5(3.67e-05)]_50 chrIII:10856985-10857065 8.24e-01 80 chrIII:11290702-11290782 6.55e-03 62_[+3(3.73e-05)]_10 chrX:5812159-5812239 4.54e-01 80 chrV:11029477-11029557 1.39e-01 80 chrI:6757209-6757289 2.39e-01 80 chrV:16553126-16553206 2.90e-01 42_[+5(4.83e-05)]_30 chrX:17315042-17315122 6.92e-01 80 chrIV:16382317-16382397 7.61e-01 80 chrII:14143968-14144048 9.80e-01 80 chrII:7072720-7072800 4.42e-01 80 chrIV:2639890-2639970 3.70e-01 80 chrII:8062347-8062427 4.37e-01 80 chrIII:3916795-3916875 6.53e-04 13_[+5(2.38e-05)]_15_[+3(9.27e-06)]_\ 36 chrI:13331019-13331099 9.72e-01 80 chrX:14804857-14804937 7.99e-02 80 chrX:2553820-2553900 6.36e-01 80 chrX:4617059-4617139 8.53e-02 80 chrII:9566208-9566288 3.35e-01 80 chrIII:9104316-9104396 1.58e-01 80 chrV:14697046-14697126 6.60e-01 80 chrI:14721609-14721689 4.27e-03 9_[+3(9.27e-06)]_63 chrI:27096-27176 1.86e-01 80 chrII:3439403-3439483 4.30e-01 80 chrIV:11026158-11026238 1.14e-01 80 chrX:2536505-2536585 4.81e-01 80 chrIII:8971757-8971837 7.28e-01 80 chrI:13310328-13310408 2.03e-01 80 chrIII:11317375-11317455 8.88e-01 80 chrX:12367732-12367812 3.34e-01 80 chrX:5707971-5708051 6.93e-02 11_[+5(7.19e-05)]_61 chrV:6785289-6785369 8.16e-01 80 chrV:12780409-12780489 4.82e-01 80 -------------------------------------------------------------------------------- ******************************************************************************** ******************************************************************************** Stopped because requested number of motifs (5) found. ******************************************************************************** CPU: c27n07.farnam.hpc.yale.internal ********************************************************************************