******************************************************************************** MEME - Motif discovery tool ******************************************************************************** MEME version 5.3.3 (Release date: Sun Feb 7 15:39:52 2021 -0800) For further information on how to interpret these results please access https://meme-suite.org/meme. To get a copy of the MEME Suite software please access https://meme-suite.org. ******************************************************************************** ******************************************************************************** REFERENCE ******************************************************************************** If you use this program in your research, please cite: Timothy L. Bailey and Charles Elkan, "Fitting a mixture model by expectation maximization to discover motifs in biopolymers", Proceedings of the Second International Conference on Intelligent Systems for Molecular Biology, pp. 28-36, AAAI Press, Menlo Park, California, 1994. ******************************************************************************** ******************************************************************************** TRAINING SET ******************************************************************************** PRIMARY SEQUENCES= ../result/final_prediction/worm/fasta/RankLinear2.0_40/cey-2.fasta CONTROL SEQUENCES= --none-- ALPHABET= ACGT Sequence name Weight Length Sequence name Weight Length ------------- ------ ------ ------------- ------ ------ chrI:9538014-9538094 1.0000 80 chrIV:7178991-7179071 1.0000 80 chrII:10169044-10169124 1.0000 80 chrI:10409707-10409787 1.0000 80 chrV:8406991-8407071 1.0000 80 chrIV:6555554-6555634 1.0000 80 chrV:19612155-19612235 1.0000 80 chrX:10639570-10639650 1.0000 80 chrV:11087308-11087388 1.0000 80 chrIV:9563245-9563325 1.0000 80 chrV:6652284-6652364 1.0000 80 chrII:5049404-5049484 1.0000 80 chrIV:9112124-9112204 1.0000 80 chrIV:13682908-13682988 1.0000 80 chrIV:4795215-4795295 1.0000 80 chrIV:11914889-11914969 1.0000 80 chrV:10886559-10886639 1.0000 80 chrI:8869176-8869256 1.0000 80 chrII:6562289-6562369 1.0000 80 chrIV:17474226-17474306 1.0000 80 chrX:2593001-2593081 1.0000 80 chrIV:13079229-13079309 1.0000 80 chrV:6365810-6365890 1.0000 80 chrIV:12110255-12110335 1.0000 80 chrV:8383911-8383991 1.0000 80 chrIII:154335-154415 1.0000 80 chrIII:3104733-3104813 1.0000 80 chrV:11676641-11676721 1.0000 80 chrIV:8979962-8980042 1.0000 80 chrV:8026512-8026592 1.0000 80 chrIII:7203223-7203303 1.0000 80 chrIV:1718242-1718322 1.0000 80 chrV:20648993-20649073 1.0000 80 chrIV:9051886-9051966 1.0000 80 chrII:5283005-5283085 1.0000 80 chrIV:302359-302439 1.0000 80 chrIII:7020950-7021030 1.0000 80 chrIV:5216448-5216528 1.0000 80 chrIV:12400102-12400182 1.0000 80 chrV:4965138-4965218 1.0000 80 chrI:3530989-3531069 1.0000 80 chrIV:11901361-11901441 1.0000 80 chrV:13085380-13085460 1.0000 80 chrIV:9634114-9634194 1.0000 80 chrV:14660760-14660840 1.0000 80 chrIII:9389450-9389530 1.0000 80 chrV:5823169-5823249 1.0000 80 chrII:14489581-14489661 1.0000 80 chrV:12301169-12301249 1.0000 80 chrX:11720179-11720259 1.0000 80 chrV:6429999-6430079 1.0000 80 chrIII:8504282-8504362 1.0000 80 chrIII:6144581-6144661 1.0000 80 chrIII:6509580-6509660 1.0000 80 chrV:8449349-8449429 1.0000 80 chrII:6026774-6026854 1.0000 80 chrIII:8867541-8867621 1.0000 80 chrV:20712466-20712546 1.0000 80 chrIV:11211716-11211796 1.0000 80 chrII:10019762-10019842 1.0000 80 chrX:9527964-9528044 1.0000 80 chrV:8655148-8655228 1.0000 80 chrV:13202345-13202425 1.0000 80 chrV:4911652-4911732 1.0000 80 chrIII:7305131-7305211 1.0000 80 chrII:8818430-8818510 1.0000 80 chrV:8768663-8768743 1.0000 80 chrII:8440856-8440936 1.0000 80 chrII:7631337-7631417 1.0000 80 chrIII:6422145-6422225 1.0000 80 chrIII:12842990-12843070 1.0000 80 chrIV:8528605-8528685 1.0000 80 chrII:1103854-1103934 1.0000 80 chrX:15161245-15161325 1.0000 80 chrII:12549867-12549947 1.0000 80 chrIV:14414396-14414476 1.0000 80 chrII:9753196-9753276 1.0000 80 chrX:15373414-15373494 1.0000 80 chrIV:11092807-11092887 1.0000 80 chrX:12425623-12425703 1.0000 80 chrV:8426867-8426947 1.0000 80 chrII:4881856-4881936 1.0000 80 chrIII:8732093-8732173 1.0000 80 chrI:4329091-4329171 1.0000 80 chrII:12625852-12625932 1.0000 80 chrII:4387956-4388036 1.0000 80 chrIV:103003-103083 1.0000 80 chrII:5886118-5886198 1.0000 80 chrIV:8042118-8042198 1.0000 80 chrV:9925799-9925879 1.0000 80 chrIV:6654032-6654112 1.0000 80 chrX:11393160-11393240 1.0000 80 chrIII:2169613-2169693 1.0000 80 chrX:11452263-11452343 1.0000 80 chrII:9586958-9587038 1.0000 80 chrI:9541027-9541107 1.0000 80 chrIV:10782140-10782220 1.0000 80 chrX:13165738-13165818 1.0000 80 chrII:8568943-8569023 1.0000 80 chrIV:10216318-10216398 1.0000 80 chrIV:7530485-7530565 1.0000 80 chrV:13892678-13892758 1.0000 80 chrX:9147172-9147252 1.0000 80 chrIII:746795-746875 1.0000 80 chrIII:10007184-10007264 1.0000 80 chrX:12844302-12844382 1.0000 80 chrIII:10985756-10985836 1.0000 80 chrII:3030326-3030406 1.0000 80 chrII:5572234-5572314 1.0000 80 chrV:13377215-13377295 1.0000 80 chrI:3085338-3085418 1.0000 80 chrIV:5605252-5605332 1.0000 80 chrII:12425977-12426057 1.0000 80 chrIII:8739311-8739391 1.0000 80 chrIV:15395478-15395558 1.0000 80 chrIII:6510685-6510765 1.0000 80 chrIII:7201486-7201566 1.0000 80 chrI:6210037-6210117 1.0000 80 chrI:3297177-3297257 1.0000 80 chrM:13159-13239 1.0000 80 chrI:8852534-8852614 1.0000 80 chrV:14510829-14510909 1.0000 80 chrV:381370-381450 1.0000 80 chrV:11534658-11534738 1.0000 80 chrII:6619147-6619227 1.0000 80 chrII:4599034-4599114 1.0000 80 chrII:10390560-10390640 1.0000 80 chrI:7661321-7661401 1.0000 80 chrV:14368335-14368415 1.0000 80 chrI:6997825-6997905 1.0000 80 chrIV:9647906-9647986 1.0000 80 chrIV:10631126-10631206 1.0000 80 chrIII:8987046-8987126 1.0000 80 chrI:8867676-8867756 1.0000 80 chrV:4918874-4918954 1.0000 80 chrIV:9868048-9868128 1.0000 80 chrV:4908714-4908794 1.0000 80 chrII:14838730-14838810 1.0000 80 chrV:11802589-11802669 1.0000 80 chrV:8651490-8651570 1.0000 80 chrV:12353320-12353400 1.0000 80 chrIV:298852-298932 1.0000 80 chrV:13378062-13378142 1.0000 80 chrIV:8864848-8864928 1.0000 80 chrII:4855993-4856073 1.0000 80 chrIV:10617080-10617160 1.0000 80 chrIII:7199775-7199855 1.0000 80 chrIV:8535123-8535203 1.0000 80 chrV:5832950-5833030 1.0000 80 chrX:5467441-5467521 1.0000 80 chrII:13681224-13681304 1.0000 80 chrII:7405429-7405509 1.0000 80 chrII:301196-301276 1.0000 80 chrII:5333750-5333830 1.0000 80 chrIII:3309087-3309167 1.0000 80 chrI:7087425-7087505 1.0000 80 chrV:11147764-11147844 1.0000 80 chrM:182-262 1.0000 80 chrX:4132501-4132581 1.0000 80 chrI:7575626-7575706 1.0000 80 chrX:12759782-12759862 1.0000 80 chrV:18346226-18346306 1.0000 80 chrII:6849525-6849605 1.0000 80 chrIII:5920135-5920215 1.0000 80 chrIV:8026548-8026628 1.0000 80 chrV:10860020-10860100 1.0000 80 chrII:162320-162400 1.0000 80 chrV:17714505-17714585 1.0000 80 chrV:10371371-10371451 1.0000 80 chrIV:10855342-10855422 1.0000 80 chrV:6994123-6994203 1.0000 80 chrV:10423517-10423597 1.0000 80 chrIII:9454937-9455017 1.0000 80 chrX:5628633-5628713 1.0000 80 chrII:7528423-7528503 1.0000 80 chrV:10938902-10938982 1.0000 80 chrIII:9500430-9500510 1.0000 80 chrV:6247649-6247729 1.0000 80 chrIV:8032287-8032367 1.0000 80 chrII:12980365-12980445 1.0000 80 chrIII:3875631-3875711 1.0000 80 chrIV:11491504-11491584 1.0000 80 chrV:3193261-3193341 1.0000 80 chrI:9168575-9168655 1.0000 80 chrIII:5921428-5921508 1.0000 80 chrV:6736946-6737026 1.0000 80 chrV:11799419-11799499 1.0000 80 chrV:1438989-1439069 1.0000 80 chrIV:9672536-9672616 1.0000 80 chrV:9160845-9160925 1.0000 80 chrV:10293144-10293224 1.0000 80 chrV:8403253-8403333 1.0000 80 chrX:10689863-10689943 1.0000 80 chrII:2378697-2378777 1.0000 80 chrI:10758158-10758238 1.0000 80 chrII:13954308-13954388 1.0000 80 chrV:5393161-5393241 1.0000 80 chrV:5763976-5764056 1.0000 80 chrV:11803594-11803674 1.0000 80 chrV:9633386-9633466 1.0000 80 chrV:15880797-15880877 1.0000 80 chrII:10543508-10543588 1.0000 80 chrIV:9516965-9517045 1.0000 80 chrV:10717402-10717482 1.0000 80 chrIV:247726-247806 1.0000 80 chrV:9085994-9086074 1.0000 80 chrIII:9269233-9269313 1.0000 80 chrII:7287257-7287337 1.0000 80 chrII:6822491-6822571 1.0000 80 chrIII:5550428-5550508 1.0000 80 chrI:4804743-4804823 1.0000 80 chrV:5768353-5768433 1.0000 80 chrIII:6148475-6148555 1.0000 80 chrII:5185389-5185469 1.0000 80 chrM:7664-7744 1.0000 80 chrX:3819281-3819361 1.0000 80 chrII:5320350-5320430 1.0000 80 chrIV:3653583-3653663 1.0000 80 chrIII:3029972-3030052 1.0000 80 chrV:14505883-14505963 1.0000 80 chrX:10084244-10084324 1.0000 80 chrII:5202086-5202166 1.0000 80 chrV:19527760-19527840 1.0000 80 chrII:8222787-8222867 1.0000 80 chrII:13679991-13680071 1.0000 80 chrIV:12716106-12716186 1.0000 80 chrV:13081259-13081339 1.0000 80 chrIV:8949781-8949861 1.0000 80 chrM:8541-8621 1.0000 80 chrV:13380353-13380433 1.0000 80 chrIV:8530709-8530789 1.0000 80 chrIV:11897849-11897929 1.0000 80 chrII:7059352-7059432 1.0000 80 chrII:7777373-7777453 1.0000 80 chrIV:13919363-13919443 1.0000 80 chrIV:8028476-8028556 1.0000 80 chrX:11727901-11727981 1.0000 80 chrM:1751-1831 1.0000 80 chrIV:296937-297017 1.0000 80 chrII:6327505-6327585 1.0000 80 chrX:17063846-17063926 1.0000 80 chrI:7659202-7659282 1.0000 80 chrIV:8830711-8830791 1.0000 80 chrIV:13077942-13078022 1.0000 80 chrIII:4494726-4494806 1.0000 80 chrII:9128338-9128418 1.0000 80 chrX:2891517-2891597 1.0000 80 chrV:6323056-6323136 1.0000 80 chrIII:12849299-12849379 1.0000 80 chrIII:13767084-13767164 1.0000 80 ******************************************************************************** ******************************************************************************** COMMAND LINE SUMMARY ******************************************************************************** This information can also be useful in the event you wish to report a problem with the MEME software. command: meme -oc ../result/final_prediction/worm/inference_raw/MEME/RankLinear2.0_40_cey-2/ -dna -nmotifs 5 -w 8 -maxsize 250000 -nostatus ../result/final_prediction/worm/fasta/RankLinear2.0_40/cey-2.fasta model: mod= zoops nmotifs= 5 evt= inf objective function: em= E-value of product of p-values starts= E-value of product of p-values strands: + width: minw= 8 maxw= 8 nsites: minsites= 2 maxsites= 250 wnsites= 0.8 theta: spmap= uni spfuzz= 0.5 em: prior= dirichlet b= 0.01 maxiter= 50 distance= 1e-05 trim: wg= 11 ws= 1 endgaps= yes data: n= 20000 N= 250 sample: seed= 0 hsfrac= 0 searchsize= 20000 norand= no csites= 1000 Letter frequencies in dataset: A 0.312 C 0.188 G 0.189 T 0.311 Background letter frequencies (from file dataset with add-one prior applied): A 0.312 C 0.188 G 0.189 T 0.311 Background model order: 0 ******************************************************************************** ******************************************************************************** MOTIF VAAAAAAR MEME-1 width = 8 sites = 75 llr = 541 E-value = 2.4e-009 ******************************************************************************** -------------------------------------------------------------------------------- Motif VAAAAAAR MEME-1 Description -------------------------------------------------------------------------------- Simplified A 3aaaa963 pos.-specific C 4:::::2: probability G 4::::127 matrix T :::::::: bits 2.4 2.2 1.9 1.7 * ** Relative 1.4 ***** Entropy 1.2 ***** * (10.4 bits) 1.0 ***** * 0.7 ******** 0.5 ******** 0.2 ******** 0.0 -------- Multilevel CAAAAAAG consensus G GA sequence A -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif VAAAAAAR MEME-1 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chrIV:13077942-13078022 13 6.57e-05 GTCACCAGTC GAAAAAAG GAAAAAAAGA chrIII:5921428-5921508 11 6.57e-05 TGTGTGTTAA GAAAAAAG ATCAGCACAC chrV:3193261-3193341 29 6.57e-05 AGAGACGTAA GAAAAAAG CGTTCGGAGA chrIII:9454937-9455017 33 6.57e-05 AGAGGTTGCA GAAAAAAG AAAAATTGCG chrII:13681224-13681304 10 6.57e-05 GGTTGTTAT CAAAAAAG GCGATAGCAA chrV:5832950-5833030 72 6.57e-05 GGGCGACAGT CAAAAAAG G chrI:6997825-6997905 38 6.57e-05 AAGTAGCAAG CAAAAAAG TGCTTTTGTT chrX:11452263-11452343 15 6.57e-05 TAACTTTCAC CAAAAAAG TCGCTGATTT chrII:9753196-9753276 54 6.57e-05 CGCAAAAAAT GAAAAAAG GAGAAGAGTA chrII:10019762-10019842 53 6.57e-05 CAAAACCTTA CAAAAAAG GGCGAAAATC chrX:11720179-11720259 43 6.57e-05 TTGAGTTAAT GAAAAAAG CGCCGAGAAC chrIII:9389450-9389530 67 6.57e-05 ACCAGCCCTG CAAAAAAG CGTTTA chrV:11676641-11676721 63 6.57e-05 TCTTAGCGTA GAAAAAAG TCATCTAATT chrI:8869176-8869256 60 6.57e-05 ATGAAAAATT GAAAAAAG ACAAAAAGTT chrIV:9563245-9563325 50 6.57e-05 aaaaaaaaat gaaaaaag gaaacagtga chrIV:13919363-13919443 54 1.06e-04 GAGAATCGGT CAAAAAGG TTCAGTGACA chrII:10543508-10543588 43 1.06e-04 GGAGTATGTG GAAAAAGG GTGCAACGTG chrIV:10631126-10631206 53 1.06e-04 ATGAAAATGT CAAAAAGG TGGGGAAAAA chrI:3297177-3297257 8 1.06e-04 GAAAAGT CAAAAAGG TACAAACTAT chrIII:6510685-6510765 56 1.06e-04 TCGGTGTTAT CAAAAAGG AACTGATAAT chrIII:8739311-8739391 53 1.06e-04 TGTGTGCGTT CAAAAAGG CACTTTGTTA chrIII:3104733-3104813 28 1.06e-04 GAAAACAAGT GAAAAAGG TACAGGGTAC chrV:6365810-6365890 35 1.06e-04 GCAATGACCA CAAAAAGG ACTACACTGT chrIII:4494726-4494806 67 1.60e-04 TTGGCGCGAG AAAAAAAG CGGTGG chrX:17063846-17063926 21 1.60e-04 CAGAAATTGA AAAAAAAG GAGGCGAAGA chrII:13679991-13680071 41 1.60e-04 AAGCCAAAAA AAAAAAAG AATAAATATT chrV:10293144-10293224 16 1.60e-04 AGATGATATG AAAAAAAG GGAACGCTTT chrV:9160845-9160925 68 1.60e-04 TGAAAAAGCC AAAAAAAG ATATT chrV:10860020-10860100 32 1.60e-04 GATAAAGAAA AAAAAAAG TAAGTATTTT chrI:7661321-7661401 40 1.60e-04 CAGTCACTCC AAAAAAAG AAGGCGTTGA chrI:6210037-6210117 17 1.60e-04 TGTGAATAAG AAAAAAAG AACAACAAAA chrX:15161245-15161325 10 1.60e-04 TGGAATGGA AAAAAAAG TATGGAATTG chrIII:7305131-7305211 53 1.60e-04 ACCAAAAACA AAAAAAAG AGTAGAGAGA chrV:13202345-13202425 39 1.60e-04 CTCGAAATAC AAAAAAAG AGAGAAGTAA chrII:14489581-14489661 3 1.60e-04 aa aaaaaaag aaaaagaaag chrII:6562289-6562369 64 1.60e-04 TAAAAAACCA AAAAAAAG TCTCTATTA chrV:19612155-19612235 73 1.60e-04 AGAAAACTGA AAAAAAAG chrIV:6555554-6555634 12 1.60e-04 TTATTCAAAT AAAAAAAG TTGCGATAAG chrV:13378062-13378142 62 2.00e-04 AACTGAAAGA CAAAAACG GCAGTATCTT chrII:8568943-8569023 72 2.00e-04 ACAAGGGCGC CAAAAACG G chrV:1438989-1439069 51 3.08e-04 GTGAAAACAA GAAAAAAA TCTTGTCCCG chrV:4911652-4911732 41 3.08e-04 TGTATCAGGT GAAAAAAA ACATAAATAC chrV:8449349-8449429 15 3.08e-04 ACAAAAACCG CAAAAAAA ACGACTTCGT chrV:12301169-12301249 20 3.08e-04 GTTGTCGACA GAAAAAAA AACATTGATT chrI:3530989-3531069 39 3.08e-04 TTATCGAAAT GAAAAAAA AAACGAAGAC chrV:4965138-4965218 31 3.08e-04 GAATATTGAA CAAAAAAA CGATGATGAC chrIV:12400102-12400182 54 3.08e-04 CTTTAATCAT CAAAAAAA AAACATGATT chrIV:5216448-5216528 12 3.08e-04 ACAAAATCGA GAAAAAAA CTGTGAGAAT chrII:5283005-5283085 20 3.08e-04 AAGGCAGACA GAAAAAAA AATGAGACGA chrIV:1718242-1718322 43 3.08e-04 ATGGAAGAAG GAAAAAAA AATCACAGAA chrIII:746795-746875 11 3.74e-04 GATGGAAGAG AAAAAACG ATGAAAAGAG chrII:4881856-4881936 66 3.74e-04 TTGCAACAAC AAAAAACG ATGACTA chrII:7059352-7059432 52 4.39e-04 TTTTCGTTAT CAAAAAGA GAGAAGAATT chrII:5185389-5185469 33 4.39e-04 CATAAACACT GAAAAAGA AAGAGAGATG chrIV:9647906-9647986 46 4.39e-04 GATTCATTGG GAAAAAGA AGAAGAAAGT chrX:12425623-12425703 11 4.39e-04 AACCAAAATG CAAAAAGA AAAAGAGAGA chrIII:8504282-8504362 49 4.39e-04 ATCTTTCTCT CAAAAAGA TTCAATATCA chrII:5049404-5049484 35 4.39e-04 GTTTTTTCTT CAAAAAGA ACATCGGTTC chrIII:12842990-12843070 7 5.29e-04 CTCTTT AAAAAAAA CTAGAAGAAT chrV:18346226-18346306 27 5.95e-04 CAAAAAATCG CAAAAACA AATGCGGAAC chrV:4908714-4908794 31 5.95e-04 AATTAGCCAT GAAAAACA TATGTCATCA chrII:10390560-10390640 36 5.95e-04 CATTCACACA CAAAAACA CAGTGTTGTG chrII:12425977-12426057 60 5.95e-04 TTAATGATTT GAAAAACA AGAAGTAATT chrIV:8042118-8042198 63 5.95e-04 ACCGGTTTTA CAAAAACA TTTCGATGAA chrIV:11092807-11092887 10 5.95e-04 CTTCTACAG CAAAAACA ATCATTTTCA chrIV:9051886-9051966 63 5.95e-04 TTTAATAAAT GAAAAACA GATCTAGGAG chrV:9633386-9633466 66 6.89e-04 AGTTTGAAAT CAAAAGAG ACGTAGA chrIV:11491504-11491584 7 6.89e-04 CTTTCA GAAAAGAG AAAATATATA chrIII:8867541-8867621 69 6.89e-04 ATATTGGGAC GAAAAGAG AAAG chrI:10409707-10409787 54 6.89e-04 GACACCATAT AAAAAAGA ACAAATGAAA chrX:2891517-2891597 55 7.29e-04 CGAGAGGACA GAGAAAAG AAGATGTTTA chrII:4387956-4388036 34 7.29e-04 AGAACACACA CAGAAAAG AATGAAAATG chrV:14505883-14505963 15 7.83e-04 AACACCGCGC AAAAAACA CTGTGAAGCA chrI:8867676-8867756 60 8.07e-04 GGTATAAAAT GAAAAGGG AATGGGGCAA chrIII:7199775-7199855 61 9.21e-04 TATTGTTTTT AAGAAAAG TACAGAGATT -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif VAAAAAAR MEME-1 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chrIV:13077942-13078022 6.6e-05 12_[+1]_60 chrIII:5921428-5921508 6.6e-05 10_[+1]_62 chrV:3193261-3193341 6.6e-05 28_[+1]_44 chrIII:9454937-9455017 6.6e-05 32_[+1]_40 chrII:13681224-13681304 6.6e-05 9_[+1]_63 chrV:5832950-5833030 6.6e-05 71_[+1]_1 chrI:6997825-6997905 6.6e-05 37_[+1]_35 chrX:11452263-11452343 6.6e-05 14_[+1]_58 chrII:9753196-9753276 6.6e-05 53_[+1]_19 chrII:10019762-10019842 6.6e-05 52_[+1]_20 chrX:11720179-11720259 6.6e-05 42_[+1]_30 chrIII:9389450-9389530 6.6e-05 66_[+1]_6 chrV:11676641-11676721 6.6e-05 62_[+1]_10 chrI:8869176-8869256 6.6e-05 59_[+1]_13 chrIV:9563245-9563325 6.6e-05 49_[+1]_23 chrIV:13919363-13919443 0.00011 53_[+1]_19 chrII:10543508-10543588 0.00011 42_[+1]_30 chrIV:10631126-10631206 0.00011 52_[+1]_20 chrI:3297177-3297257 0.00011 7_[+1]_65 chrIII:6510685-6510765 0.00011 55_[+1]_17 chrIII:8739311-8739391 0.00011 52_[+1]_20 chrIII:3104733-3104813 0.00011 27_[+1]_45 chrV:6365810-6365890 0.00011 34_[+1]_38 chrIII:4494726-4494806 0.00016 66_[+1]_6 chrX:17063846-17063926 0.00016 20_[+1]_52 chrII:13679991-13680071 0.00016 40_[+1]_32 chrV:10293144-10293224 0.00016 15_[+1]_57 chrV:9160845-9160925 0.00016 67_[+1]_5 chrV:10860020-10860100 0.00016 31_[+1]_41 chrI:7661321-7661401 0.00016 39_[+1]_33 chrI:6210037-6210117 0.00016 16_[+1]_56 chrX:15161245-15161325 0.00016 9_[+1]_63 chrIII:7305131-7305211 0.00016 52_[+1]_20 chrV:13202345-13202425 0.00016 38_[+1]_34 chrII:14489581-14489661 0.00016 2_[+1]_70 chrII:6562289-6562369 0.00016 63_[+1]_9 chrV:19612155-19612235 0.00016 72_[+1] chrIV:6555554-6555634 0.00016 11_[+1]_61 chrV:13378062-13378142 0.0002 61_[+1]_11 chrII:8568943-8569023 0.0002 71_[+1]_1 chrV:1438989-1439069 0.00031 50_[+1]_22 chrV:4911652-4911732 0.00031 40_[+1]_32 chrV:8449349-8449429 0.00031 14_[+1]_58 chrV:12301169-12301249 0.00031 19_[+1]_53 chrI:3530989-3531069 0.00031 38_[+1]_34 chrV:4965138-4965218 0.00031 30_[+1]_42 chrIV:12400102-12400182 0.00031 53_[+1]_19 chrIV:5216448-5216528 0.00031 11_[+1]_61 chrII:5283005-5283085 0.00031 19_[+1]_53 chrIV:1718242-1718322 0.00031 42_[+1]_30 chrIII:746795-746875 0.00037 10_[+1]_62 chrII:4881856-4881936 0.00037 65_[+1]_7 chrII:7059352-7059432 0.00044 51_[+1]_21 chrII:5185389-5185469 0.00044 32_[+1]_40 chrIV:9647906-9647986 0.00044 45_[+1]_27 chrX:12425623-12425703 0.00044 10_[+1]_62 chrIII:8504282-8504362 0.00044 48_[+1]_24 chrII:5049404-5049484 0.00044 34_[+1]_38 chrIII:12842990-12843070 0.00053 6_[+1]_66 chrV:18346226-18346306 0.00059 26_[+1]_46 chrV:4908714-4908794 0.00059 30_[+1]_42 chrII:10390560-10390640 0.00059 35_[+1]_37 chrII:12425977-12426057 0.00059 59_[+1]_13 chrIV:8042118-8042198 0.00059 62_[+1]_10 chrIV:11092807-11092887 0.00059 9_[+1]_63 chrIV:9051886-9051966 0.00059 62_[+1]_10 chrV:9633386-9633466 0.00069 65_[+1]_7 chrIV:11491504-11491584 0.00069 6_[+1]_66 chrIII:8867541-8867621 0.00069 68_[+1]_4 chrI:10409707-10409787 0.00069 53_[+1]_19 chrX:2891517-2891597 0.00073 54_[+1]_18 chrII:4387956-4388036 0.00073 33_[+1]_39 chrV:14505883-14505963 0.00078 14_[+1]_58 chrI:8867676-8867756 0.00081 59_[+1]_13 chrIII:7199775-7199855 0.00092 60_[+1]_12 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif VAAAAAAR MEME-1 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF VAAAAAAR width=8 seqs=75 chrIV:13077942-13078022 ( 13) GAAAAAAG 1 chrIII:5921428-5921508 ( 11) GAAAAAAG 1 chrV:3193261-3193341 ( 29) GAAAAAAG 1 chrIII:9454937-9455017 ( 33) GAAAAAAG 1 chrII:13681224-13681304 ( 10) CAAAAAAG 1 chrV:5832950-5833030 ( 72) CAAAAAAG 1 chrI:6997825-6997905 ( 38) CAAAAAAG 1 chrX:11452263-11452343 ( 15) CAAAAAAG 1 chrII:9753196-9753276 ( 54) GAAAAAAG 1 chrII:10019762-10019842 ( 53) CAAAAAAG 1 chrX:11720179-11720259 ( 43) GAAAAAAG 1 chrIII:9389450-9389530 ( 67) CAAAAAAG 1 chrV:11676641-11676721 ( 63) GAAAAAAG 1 chrI:8869176-8869256 ( 60) GAAAAAAG 1 chrIV:9563245-9563325 ( 50) GAAAAAAG 1 chrIV:13919363-13919443 ( 54) CAAAAAGG 1 chrII:10543508-10543588 ( 43) GAAAAAGG 1 chrIV:10631126-10631206 ( 53) CAAAAAGG 1 chrI:3297177-3297257 ( 8) CAAAAAGG 1 chrIII:6510685-6510765 ( 56) CAAAAAGG 1 chrIII:8739311-8739391 ( 53) CAAAAAGG 1 chrIII:3104733-3104813 ( 28) GAAAAAGG 1 chrV:6365810-6365890 ( 35) CAAAAAGG 1 chrIII:4494726-4494806 ( 67) AAAAAAAG 1 chrX:17063846-17063926 ( 21) AAAAAAAG 1 chrII:13679991-13680071 ( 41) AAAAAAAG 1 chrV:10293144-10293224 ( 16) AAAAAAAG 1 chrV:9160845-9160925 ( 68) AAAAAAAG 1 chrV:10860020-10860100 ( 32) AAAAAAAG 1 chrI:7661321-7661401 ( 40) AAAAAAAG 1 chrI:6210037-6210117 ( 17) AAAAAAAG 1 chrX:15161245-15161325 ( 10) AAAAAAAG 1 chrIII:7305131-7305211 ( 53) AAAAAAAG 1 chrV:13202345-13202425 ( 39) AAAAAAAG 1 chrII:14489581-14489661 ( 3) AAAAAAAG 1 chrII:6562289-6562369 ( 64) AAAAAAAG 1 chrV:19612155-19612235 ( 73) AAAAAAAG 1 chrIV:6555554-6555634 ( 12) AAAAAAAG 1 chrV:13378062-13378142 ( 62) CAAAAACG 1 chrII:8568943-8569023 ( 72) CAAAAACG 1 chrV:1438989-1439069 ( 51) GAAAAAAA 1 chrV:4911652-4911732 ( 41) GAAAAAAA 1 chrV:8449349-8449429 ( 15) CAAAAAAA 1 chrV:12301169-12301249 ( 20) GAAAAAAA 1 chrI:3530989-3531069 ( 39) GAAAAAAA 1 chrV:4965138-4965218 ( 31) CAAAAAAA 1 chrIV:12400102-12400182 ( 54) CAAAAAAA 1 chrIV:5216448-5216528 ( 12) GAAAAAAA 1 chrII:5283005-5283085 ( 20) GAAAAAAA 1 chrIV:1718242-1718322 ( 43) GAAAAAAA 1 chrIII:746795-746875 ( 11) AAAAAACG 1 chrII:4881856-4881936 ( 66) AAAAAACG 1 chrII:7059352-7059432 ( 52) CAAAAAGA 1 chrII:5185389-5185469 ( 33) GAAAAAGA 1 chrIV:9647906-9647986 ( 46) GAAAAAGA 1 chrX:12425623-12425703 ( 11) CAAAAAGA 1 chrIII:8504282-8504362 ( 49) CAAAAAGA 1 chrII:5049404-5049484 ( 35) CAAAAAGA 1 chrIII:12842990-12843070 ( 7) AAAAAAAA 1 chrV:18346226-18346306 ( 27) CAAAAACA 1 chrV:4908714-4908794 ( 31) GAAAAACA 1 chrII:10390560-10390640 ( 36) CAAAAACA 1 chrII:12425977-12426057 ( 60) GAAAAACA 1 chrIV:8042118-8042198 ( 63) CAAAAACA 1 chrIV:11092807-11092887 ( 10) CAAAAACA 1 chrIV:9051886-9051966 ( 63) GAAAAACA 1 chrV:9633386-9633466 ( 66) CAAAAGAG 1 chrIV:11491504-11491584 ( 7) GAAAAGAG 1 chrIII:8867541-8867621 ( 69) GAAAAGAG 1 chrI:10409707-10409787 ( 54) AAAAAAGA 1 chrX:2891517-2891597 ( 55) GAGAAAAG 1 chrII:4387956-4388036 ( 34) CAGAAAAG 1 chrV:14505883-14505963 ( 15) AAAAAACA 1 chrI:8867676-8867756 ( 60) GAAAAGGG 1 chrIII:7199775-7199855 ( 61) AAGAAAAG 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif VAAAAAAR MEME-1 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 9.3564 E= 2.4e-009 -16 94 93 -1287 168 -1287 -1287 -1287 162 -1287 -224 -1287 168 -1287 -1287 -1287 168 -1287 -1287 -1287 160 -1287 -182 -1287 101 -23 18 -1287 15 -1287 179 -1287 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif VAAAAAAR MEME-1 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 75 E= 2.4e-009 0.280000 0.360000 0.360000 0.000000 1.000000 0.000000 0.000000 0.000000 0.960000 0.000000 0.040000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.946667 0.000000 0.053333 0.000000 0.626667 0.160000 0.213333 0.000000 0.346667 0.000000 0.653333 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif VAAAAAAR MEME-1 regular expression -------------------------------------------------------------------------------- [CGA]AAAAA[AG][GA] -------------------------------------------------------------------------------- Time 5.36 secs. ******************************************************************************** ******************************************************************************** MOTIF TTTTTYTY MEME-2 width = 8 sites = 88 llr = 591 E-value = 4.5e-002 ******************************************************************************** -------------------------------------------------------------------------------- Motif TTTTTYTY MEME-2 Description -------------------------------------------------------------------------------- Simplified A :::::::: pos.-specific C 1223:7:5 probability G :::::::2 matrix T 9887a3a3 bits 2.4 2.2 1.9 1.7 * * Relative 1.4 * * Entropy 1.2 * * *** (9.7 bits) 1.0 ******* 0.7 ******** 0.5 ******** 0.2 ******** 0.0 -------- Multilevel TTTTTCTC consensus CCC T T sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTTTTYTY MEME-2 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chrV:14510829-14510909 65 3.20e-05 CATTTTCCCT TTTTTCTC ATCAATCA chrIV:15395478-15395558 26 3.20e-05 TCGCAGAAAC TTTTTCTC TTCCCCACTG chrIII:10985756-10985836 2 3.20e-05 T TTTTTCTC AAATAGTCAT chrII:10169044-10169124 16 3.20e-05 CTGTATCTTT TTTTTCTC CAATTCAATG chrIII:9500430-9500510 28 5.13e-05 GCTCTCTAAC TTTCTCTC GCACCGCTGA chrIII:8987046-8987126 6 5.13e-05 ATCAA TTtctctc tttctatccc chrII:4599034-4599114 31 5.13e-05 TCTTCCACTC TTTCTCTC TCTCTCAATT chrV:20648993-20649073 20 5.13e-05 TCTCTCAACT TTTCTCTC ATTTTCCCTT chrIV:9112124-9112204 63 5.13e-05 CTCTCATCAC TTTCTCTC TTTGATTCCG chrV:10293144-10293224 68 7.06e-05 GACCGCTTTC TCTTTCTC GGAGA chrII:13681224-13681304 35 7.06e-05 CAACCATAAA TCTTTCTC CTCCTCTGTT chrX:13165738-13165818 45 7.06e-05 CTCTATTTTC TCTTTCTC TTTCGACTAT chrIII:8504282-8504362 40 7.06e-05 TTGCACGTTA TCTTTCTC TCAAAAAGAT chrII:6849525-6849605 26 9.00e-05 TGTCCCCATC TTCTTCTC TGTTCGCTCA chrII:301196-301276 63 9.00e-05 AGTGCCTGTG TTCTTCTC CTTCTTCTTT chrII:10390560-10390640 54 9.00e-05 CAGTGTTGTG TTCTTCTC TTTTTTTCGA chrII:8568943-8569023 16 9.00e-05 CAGTTACAAT TTCTTCTC TCATCGTGTC chrV:8449349-8449429 33 9.00e-05 ACGACTTCGT TTCTTCTC TAATCATCTT chrV:10886559-10886639 72 9.00e-05 GTTTCACTGT TTCTTCTC T chrIII:3309087-3309167 59 1.02e-04 tctctccatc tctctctc ttctcCACAG chrIII:7201486-7201566 42 1.02e-04 TCGCTTTCTG TCTCTCTC ATTCAGGTCA chrIII:2169613-2169693 22 1.02e-04 ACGGTTTCAT TCTCTCTC GTCGGTTTTT chrII:9128338-9128418 29 1.66e-04 TTTCCAACAG TTTTTCTT CTAGAACCAT chrV:13081259-13081339 36 1.66e-04 CGTGGCAACA TTCCTCTC TCTATTTCCA chrIII:3029972-3030052 60 1.66e-04 ctttttatta tttttctt catctttatc chrV:10717402-10717482 58 1.66e-04 TACGTCTTCG TTTTTCTT TTCGTGTCAT chrIV:9672536-9672616 12 1.66e-04 atctattcct tttttctt cattctCCCA chrM:182-262 10 1.66e-04 AAAGAAGTT TTTTTCTT ATCTTTTCAC chrII:5333750-5333830 33 1.66e-04 TGTCTGTGTT TTTTTCTT CCAACCACAC chrV:14368335-14368415 4 1.66e-04 TTT TTCCTCTC ATTCCGAAAC chrII:5572234-5572314 49 1.66e-04 TTTCCTCCCG TTTTTCTT CCTGCGTCTC chrV:13085380-13085460 56 1.66e-04 TCTTTTTCTT TTTTTCTT CGACATTCGA chrIII:7203223-7203303 17 1.66e-04 CAAATCATCG TTTTTCTT CTTGTCAATT chrII:5049404-5049484 27 1.66e-04 TGTCAATCGT TTTTTCTT CAAAAAGAAC chrI:10758158-10758238 45 2.51e-04 CCTTCCATTT TTTTTTTC GATGACAGTT chrIV:11491504-11491584 48 2.51e-04 AGATACTTGG TTTTTTTC GCTCGGCGCT chrII:4881856-4881936 10 2.51e-04 TTGCATATA TTTTTTTC AACCAATATT chrX:15373414-15373494 20 2.51e-04 tttttttgtt tttttttc attttctttt chrV:4911652-4911732 25 2.51e-04 CTAAATAATG TTTTTCTG TATCAGGTGA chrX:2593001-2593081 44 2.51e-04 TGTTGAAACT TTTTTTTC GGTTATGGAA chrX:10639570-10639650 22 2.51e-04 TTTTTTAAGT TTTTTTTC GATTCAGACA chrIV:11914889-11914969 5 2.83e-04 TCTA TTTCTCTT CAATTCCCAT chrIV:247726-247806 30 3.35e-04 TTTCTCTATG TTTCTTTC GAATTTGTGT chrV:5763976-5764056 40 3.35e-04 AGGAACAGAT TTTCTCTG GGTCTCTTCG chrV:13202345-13202425 11 3.35e-04 CCATTAGGGG TTTCTCTG TCAAATTGAC chrII:6026774-6026854 48 3.35e-04 GAATTGTCAT TTTCTCTG TTTCTCTATG chrIII:7020950-7021030 30 3.35e-04 CCAGTTAGCA TTTCTCTG AAACTCTCCA chrIV:4795215-4795295 58 3.35e-04 CAGCCGCCGT TTTCTTTC GTTTTTTCGA chrIV:7178991-7179071 22 3.35e-04 TGTCAAATAG TTTCTCTG AATCACTATT chrV:9633386-9633466 34 3.66e-04 TTCAGTATAT CTTTTCTC GTAGAATGTG chrIV:8979962-8980042 21 3.66e-04 CTCTTCTTCG CTTTTCTC TACGTCGCTT chrII:5886118-5886198 18 4.16e-04 GGATTCGCTT TCCCTCTC TTTTCACTTG chrIII:7305131-7305211 20 4.16e-04 CGGTTCATCA TCCCTCTC CTATCACCGA chrV:6323056-6323136 8 5.00e-04 GTATGTA TCTTTCTG TGTTTTGTTA chrII:12980365-12980445 24 5.00e-04 GGCGTTCTTG TTCTTCTT ATCACCTATT chrV:10423517-10423597 14 5.00e-04 AATTCTGTCT TCTTTTTC CGCATTACAA chrIV:7530485-7530565 25 5.00e-04 CACTTTACAC TTCTTCTT TTTTCATTTC chrIII:6509580-6509660 33 5.00e-04 GTCTTGGGAA TCTTTTTC ACTTCTGTAA chrIII:13767084-13767164 1 5.71e-04 . TCTCTCTT ATCACGTGAT chrI:7659202-7659282 14 5.71e-04 TGACCCCGCC TCTCTCTT GTACACACGT chrI:10409707-10409787 18 5.71e-04 CATCAAAATG TTCTTTTC CCTCTTGAAC chrII:7777373-7777453 32 7.40e-04 GAAATTGTAT TTTTTTTT TGAAAGGTTT chrX:11393160-11393240 58 7.40e-04 ATATCTCTCC TTTTTTTT GGTTTTATTT chrII:12549867-12549947 64 7.40e-04 TCTCCACACA TTTTTTTT GGATGCACT chrIV:17474226-17474306 45 7.40e-04 TACACAAAAC TTTTTTTT GAGGGGCGCC chrIV:6555554-6555634 61 7.40e-04 AAAGGAGAGG TTTTTTTT GATAAATCGC chrI:7575626-7575706 50 8.04e-04 TGACGTCTGA TTTTTTTG TAGCAGCGAC chrIV:6654032-6654112 51 8.04e-04 GCTGATTTCG TTTTTTTG TTGTCGTTCA chrI:8869176-8869256 32 8.04e-04 TTTTATTTCC TTTTTTTG TTGTACCACA chrV:19612155-19612235 1 8.04e-04 . TTTTTTTG ATAACTGATA chrIV:12716106-12716186 57 8.69e-04 TGAATATCTG TTTCTTTT GATTTCTTGG chrII:162320-162400 21 8.69e-04 TGATAAGAAT CTCTTCTC TGGCCAGAAC chrV:13378062-13378142 31 8.69e-04 TGTGTAATGT CTCTTCTC GCATACTCTC chrII:4855993-4856073 6 9.08e-04 GCCAA TTTCTTTG ACTATTGTAT chrV:8426867-8426947 41 9.08e-04 GAGGGAAGAG TTTCTTTG AAAGTCACGA chrV:13377215-13377295 72 9.67e-04 TTTTTATCAG CTTTTCTT A chrV:12301169-12301249 70 9.67e-04 TCTCACTCTC TCCTTCTT ATT chrIV:12110255-12110335 20 9.67e-04 CAACAATCTA TCCTTCTT TTATACTACA chrI:9538014-9538094 48 9.67e-04 TACGTTTCGA CTTTTCTT GTTCATGTAC chrX:3819281-3819361 18 1.05e-03 ACCGTGTAAT TCCTTTTC ACTATTTCCA chrIV:9516965-9517045 59 1.05e-03 TTGTTGATAT CTTTTTTC CTATCTTTCA chrIV:9634114-9634194 21 1.05e-03 CATATCATCA CTTTTCTG TAAAAGTGAA chrV:6652284-6652364 20 1.27e-03 GCTACTTCAG TCTTTTTG TATCATTTTT chrX:10689863-10689943 6 1.34e-03 TTGCG TCTCTTTT CAATTTCCTA chrV:20712466-20712546 43 1.39e-03 TTACGGTCGC TTCCTTTT AAATAAACAC chrIV:8949781-8949861 48 1.48e-03 GTGTCCGCGC CCTTTTTC GTCTAAGTTT chrI:4329091-4329171 67 1.48e-03 TCAAGGTCAC CCTTTTTC GTTTTT chrII:7059352-7059432 68 1.55e-03 GAGAGAAGAA TTTGTCTC ATTCT -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTTTTYTY MEME-2 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chrV:14510829-14510909 3.2e-05 64_[+2]_8 chrIV:15395478-15395558 3.2e-05 25_[+2]_47 chrIII:10985756-10985836 3.2e-05 1_[+2]_71 chrII:10169044-10169124 3.2e-05 15_[+2]_57 chrIII:9500430-9500510 5.1e-05 27_[+2]_45 chrIII:8987046-8987126 5.1e-05 5_[+2]_67 chrII:4599034-4599114 5.1e-05 30_[+2]_42 chrV:20648993-20649073 5.1e-05 19_[+2]_53 chrIV:9112124-9112204 5.1e-05 62_[+2]_10 chrV:10293144-10293224 7.1e-05 67_[+2]_5 chrII:13681224-13681304 7.1e-05 34_[+2]_38 chrX:13165738-13165818 7.1e-05 44_[+2]_28 chrIII:8504282-8504362 7.1e-05 39_[+2]_33 chrII:6849525-6849605 9e-05 25_[+2]_47 chrII:301196-301276 9e-05 62_[+2]_10 chrII:10390560-10390640 9e-05 53_[+2]_19 chrII:8568943-8569023 9e-05 15_[+2]_57 chrV:8449349-8449429 9e-05 32_[+2]_40 chrV:10886559-10886639 9e-05 71_[+2]_1 chrIII:3309087-3309167 0.0001 58_[+2]_14 chrIII:7201486-7201566 0.0001 41_[+2]_31 chrIII:2169613-2169693 0.0001 21_[+2]_51 chrII:9128338-9128418 0.00017 28_[+2]_44 chrV:13081259-13081339 0.00017 35_[+2]_37 chrIII:3029972-3030052 0.00017 59_[+2]_13 chrV:10717402-10717482 0.00017 57_[+2]_15 chrIV:9672536-9672616 0.00017 11_[+2]_61 chrM:182-262 0.00017 9_[+2]_63 chrII:5333750-5333830 0.00017 32_[+2]_40 chrV:14368335-14368415 0.00017 3_[+2]_69 chrII:5572234-5572314 0.00017 48_[+2]_24 chrV:13085380-13085460 0.00017 55_[+2]_17 chrIII:7203223-7203303 0.00017 16_[+2]_56 chrII:5049404-5049484 0.00017 26_[+2]_46 chrI:10758158-10758238 0.00025 44_[+2]_28 chrIV:11491504-11491584 0.00025 47_[+2]_25 chrII:4881856-4881936 0.00025 9_[+2]_63 chrX:15373414-15373494 0.00025 19_[+2]_53 chrV:4911652-4911732 0.00025 24_[+2]_48 chrX:2593001-2593081 0.00025 43_[+2]_29 chrX:10639570-10639650 0.00025 21_[+2]_51 chrIV:11914889-11914969 0.00028 4_[+2]_68 chrIV:247726-247806 0.00033 29_[+2]_43 chrV:5763976-5764056 0.00033 39_[+2]_33 chrV:13202345-13202425 0.00033 10_[+2]_62 chrII:6026774-6026854 0.00033 47_[+2]_25 chrIII:7020950-7021030 0.00033 29_[+2]_43 chrIV:4795215-4795295 0.00033 57_[+2]_15 chrIV:7178991-7179071 0.00033 21_[+2]_51 chrV:9633386-9633466 0.00037 33_[+2]_39 chrIV:8979962-8980042 0.00037 20_[+2]_52 chrII:5886118-5886198 0.00042 17_[+2]_55 chrIII:7305131-7305211 0.00042 19_[+2]_53 chrV:6323056-6323136 0.0005 7_[+2]_65 chrII:12980365-12980445 0.0005 23_[+2]_49 chrV:10423517-10423597 0.0005 13_[+2]_59 chrIV:7530485-7530565 0.0005 24_[+2]_48 chrIII:6509580-6509660 0.0005 32_[+2]_40 chrIII:13767084-13767164 0.00057 [+2]_72 chrI:7659202-7659282 0.00057 13_[+2]_59 chrI:10409707-10409787 0.00057 17_[+2]_55 chrII:7777373-7777453 0.00074 31_[+2]_41 chrX:11393160-11393240 0.00074 57_[+2]_15 chrII:12549867-12549947 0.00074 63_[+2]_9 chrIV:17474226-17474306 0.00074 44_[+2]_28 chrIV:6555554-6555634 0.00074 60_[+2]_12 chrI:7575626-7575706 0.0008 49_[+2]_23 chrIV:6654032-6654112 0.0008 50_[+2]_22 chrI:8869176-8869256 0.0008 31_[+2]_41 chrV:19612155-19612235 0.0008 [+2]_72 chrIV:12716106-12716186 0.00087 56_[+2]_16 chrII:162320-162400 0.00087 20_[+2]_52 chrV:13378062-13378142 0.00087 30_[+2]_42 chrII:4855993-4856073 0.00091 5_[+2]_67 chrV:8426867-8426947 0.00091 40_[+2]_32 chrV:13377215-13377295 0.00097 71_[+2]_1 chrV:12301169-12301249 0.00097 69_[+2]_3 chrIV:12110255-12110335 0.00097 19_[+2]_53 chrI:9538014-9538094 0.00097 47_[+2]_25 chrX:3819281-3819361 0.001 17_[+2]_55 chrIV:9516965-9517045 0.001 58_[+2]_14 chrIV:9634114-9634194 0.001 20_[+2]_52 chrV:6652284-6652364 0.0013 19_[+2]_53 chrX:10689863-10689943 0.0013 5_[+2]_67 chrV:20712466-20712546 0.0014 42_[+2]_30 chrIV:8949781-8949861 0.0015 47_[+2]_25 chrI:4329091-4329171 0.0015 66_[+2]_6 chrII:7059352-7059432 0.0015 67_[+2]_5 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTTTTYTY MEME-2 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF TTTTTYTY width=8 seqs=88 chrV:14510829-14510909 ( 65) TTTTTCTC 1 chrIV:15395478-15395558 ( 26) TTTTTCTC 1 chrIII:10985756-10985836 ( 2) TTTTTCTC 1 chrII:10169044-10169124 ( 16) TTTTTCTC 1 chrIII:9500430-9500510 ( 28) TTTCTCTC 1 chrIII:8987046-8987126 ( 6) TTTCTCTC 1 chrII:4599034-4599114 ( 31) TTTCTCTC 1 chrV:20648993-20649073 ( 20) TTTCTCTC 1 chrIV:9112124-9112204 ( 63) TTTCTCTC 1 chrV:10293144-10293224 ( 68) TCTTTCTC 1 chrII:13681224-13681304 ( 35) TCTTTCTC 1 chrX:13165738-13165818 ( 45) TCTTTCTC 1 chrIII:8504282-8504362 ( 40) TCTTTCTC 1 chrII:6849525-6849605 ( 26) TTCTTCTC 1 chrII:301196-301276 ( 63) TTCTTCTC 1 chrII:10390560-10390640 ( 54) TTCTTCTC 1 chrII:8568943-8569023 ( 16) TTCTTCTC 1 chrV:8449349-8449429 ( 33) TTCTTCTC 1 chrV:10886559-10886639 ( 72) TTCTTCTC 1 chrIII:3309087-3309167 ( 59) TCTCTCTC 1 chrIII:7201486-7201566 ( 42) TCTCTCTC 1 chrIII:2169613-2169693 ( 22) TCTCTCTC 1 chrII:9128338-9128418 ( 29) TTTTTCTT 1 chrV:13081259-13081339 ( 36) TTCCTCTC 1 chrIII:3029972-3030052 ( 60) TTTTTCTT 1 chrV:10717402-10717482 ( 58) TTTTTCTT 1 chrIV:9672536-9672616 ( 12) TTTTTCTT 1 chrM:182-262 ( 10) TTTTTCTT 1 chrII:5333750-5333830 ( 33) TTTTTCTT 1 chrV:14368335-14368415 ( 4) TTCCTCTC 1 chrII:5572234-5572314 ( 49) TTTTTCTT 1 chrV:13085380-13085460 ( 56) TTTTTCTT 1 chrIII:7203223-7203303 ( 17) TTTTTCTT 1 chrII:5049404-5049484 ( 27) TTTTTCTT 1 chrI:10758158-10758238 ( 45) TTTTTTTC 1 chrIV:11491504-11491584 ( 48) TTTTTTTC 1 chrII:4881856-4881936 ( 10) TTTTTTTC 1 chrX:15373414-15373494 ( 20) TTTTTTTC 1 chrV:4911652-4911732 ( 25) TTTTTCTG 1 chrX:2593001-2593081 ( 44) TTTTTTTC 1 chrX:10639570-10639650 ( 22) TTTTTTTC 1 chrIV:11914889-11914969 ( 5) TTTCTCTT 1 chrIV:247726-247806 ( 30) TTTCTTTC 1 chrV:5763976-5764056 ( 40) TTTCTCTG 1 chrV:13202345-13202425 ( 11) TTTCTCTG 1 chrII:6026774-6026854 ( 48) TTTCTCTG 1 chrIII:7020950-7021030 ( 30) TTTCTCTG 1 chrIV:4795215-4795295 ( 58) TTTCTTTC 1 chrIV:7178991-7179071 ( 22) TTTCTCTG 1 chrV:9633386-9633466 ( 34) CTTTTCTC 1 chrIV:8979962-8980042 ( 21) CTTTTCTC 1 chrII:5886118-5886198 ( 18) TCCCTCTC 1 chrIII:7305131-7305211 ( 20) TCCCTCTC 1 chrV:6323056-6323136 ( 8) TCTTTCTG 1 chrII:12980365-12980445 ( 24) TTCTTCTT 1 chrV:10423517-10423597 ( 14) TCTTTTTC 1 chrIV:7530485-7530565 ( 25) TTCTTCTT 1 chrIII:6509580-6509660 ( 33) TCTTTTTC 1 chrIII:13767084-13767164 ( 1) TCTCTCTT 1 chrI:7659202-7659282 ( 14) TCTCTCTT 1 chrI:10409707-10409787 ( 18) TTCTTTTC 1 chrII:7777373-7777453 ( 32) TTTTTTTT 1 chrX:11393160-11393240 ( 58) TTTTTTTT 1 chrII:12549867-12549947 ( 64) TTTTTTTT 1 chrIV:17474226-17474306 ( 45) TTTTTTTT 1 chrIV:6555554-6555634 ( 61) TTTTTTTT 1 chrI:7575626-7575706 ( 50) TTTTTTTG 1 chrIV:6654032-6654112 ( 51) TTTTTTTG 1 chrI:8869176-8869256 ( 32) TTTTTTTG 1 chrV:19612155-19612235 ( 1) TTTTTTTG 1 chrIV:12716106-12716186 ( 57) TTTCTTTT 1 chrII:162320-162400 ( 21) CTCTTCTC 1 chrV:13378062-13378142 ( 31) CTCTTCTC 1 chrII:4855993-4856073 ( 6) TTTCTTTG 1 chrV:8426867-8426947 ( 41) TTTCTTTG 1 chrV:13377215-13377295 ( 72) CTTTTCTT 1 chrV:12301169-12301249 ( 70) TCCTTCTT 1 chrIV:12110255-12110335 ( 20) TCCTTCTT 1 chrI:9538014-9538094 ( 48) CTTTTCTT 1 chrX:3819281-3819361 ( 18) TCCTTTTC 1 chrIV:9516965-9517045 ( 59) CTTTTTTC 1 chrIV:9634114-9634194 ( 21) CTTTTCTG 1 chrV:6652284-6652364 ( 20) TCTTTTTG 1 chrX:10689863-10689943 ( 6) TCTCTTTT 1 chrV:20712466-20712546 ( 43) TTCCTTTT 1 chrIV:8949781-8949861 ( 48) CCTTTTTC 1 chrI:4329091-4329171 ( 67) CCTTTTTC 1 chrII:7059352-7059432 ( 68) TTTGTCTC 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTTTTYTY MEME-2 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 9.2272 E= 4.5e-002 -1310 -72 -1310 151 -1310 35 -1310 129 -1310 20 -1310 133 -1310 71 -405 113 -1310 -1310 -1310 168 -1310 181 -1310 13 -1310 -1310 -1310 168 -1310 148 -15 -2 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTTTTYTY MEME-2 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 88 E= 4.5e-002 0.000000 0.113636 0.000000 0.886364 0.000000 0.238636 0.000000 0.761364 0.000000 0.215909 0.000000 0.784091 0.000000 0.306818 0.011364 0.681818 0.000000 0.000000 0.000000 1.000000 0.000000 0.659091 0.000000 0.340909 0.000000 0.000000 0.000000 1.000000 0.000000 0.522727 0.170455 0.306818 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTTTTYTY MEME-2 regular expression -------------------------------------------------------------------------------- T[TC][TC][TC]T[CT]T[CT] -------------------------------------------------------------------------------- Time 9.08 secs. ******************************************************************************** ******************************************************************************** MOTIF CACGTGRH MEME-3 width = 8 sites = 20 llr = 187 E-value = 1.6e+000 ******************************************************************************** -------------------------------------------------------------------------------- Motif CACGTGRH MEME-3 Description -------------------------------------------------------------------------------- Simplified A :a::::42 pos.-specific C a:a:::23 probability G :::a:a52 matrix T ::1:a::4 bits 2.4 * * * 2.2 * ** * 1.9 * ** * 1.7 ****** Relative 1.4 ****** Entropy 1.2 ****** (13.5 bits) 1.0 ****** 0.7 ******* 0.5 ******* 0.2 ******* 0.0 -------- Multilevel CACGTGGT consensus AC sequence A -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CACGTGRH MEME-3 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chrV:13081259-13081339 24 4.35e-06 GTTAAATCTC CACGTGGC AACATTCCTC chrV:11799419-11799499 22 4.35e-06 ACAACACATT CACGTGGC GCCAACAGGC chrX:5467441-5467521 43 4.35e-06 GATAAATGAA CACGTGGC GCGAGATGAT chrIV:8949781-8949861 19 1.16e-05 GTTCGAGAGT CACGTGGT CTGAAACTCA chrV:1438989-1439069 22 1.16e-05 ATTGTTAATT CACGTGGT TCTCAAAACC chrIII:8739311-8739391 28 1.59e-05 ACTGCAACAG CACGTGGG GAAGAAGTGT chrIII:8732093-8732173 57 1.59e-05 ACAGACAACC CACGTGGG GTATCCTCTT chrV:19527760-19527840 3 3.03e-05 GA CACGTGGA AAATTCATGT chrV:11802589-11802669 23 3.03e-05 GCGTGGCGTC CACGTGGA TATGATAAGA chrIV:8028476-8028556 42 3.47e-05 CGCATCTTGT CACGTGCC TCTTCACTCA chrIV:8535123-8535203 25 3.47e-05 ATCCATGGTT CACGTGCC CCATGTCTTC chrIII:13767084-13767164 11 4.66e-05 TCTCTCTTAT CACGTGAT GATAACACAA chrI:7659202-7659282 27 4.66e-05 CTCTTGTACA CACGTGAT TGTCTGTACG chrX:10084244-10084324 17 4.66e-05 ATATCAAAGA CACGTGAT ATGCGTATGG chrIII:5921428-5921508 26 4.66e-05 AAGATCAGCA CACGTGAT AAGAAATACT chrII:12625852-12625932 36 4.66e-05 GTTTGGTCGC CACGTGAT CTTGCAAAAC chrV:13892678-13892758 27 7.72e-05 ACAGTCGATA CACGTGAA CATGAATCAT chrII:8818430-8818510 37 7.72e-05 GACACGCCGA CACGTGCG GTGGTTAGAG chrIII:6144581-6144661 30 7.72e-05 TAGCGGAAAA CACGTGAA TACGAAAACT chrII:14838730-14838810 45 9.16e-05 CCGCCATCAA CATGTGGC TTCCGTGTAG -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CACGTGRH MEME-3 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chrV:13081259-13081339 4.4e-06 23_[+3]_49 chrV:11799419-11799499 4.4e-06 21_[+3]_51 chrX:5467441-5467521 4.4e-06 42_[+3]_30 chrIV:8949781-8949861 1.2e-05 18_[+3]_54 chrV:1438989-1439069 1.2e-05 21_[+3]_51 chrIII:8739311-8739391 1.6e-05 27_[+3]_45 chrIII:8732093-8732173 1.6e-05 56_[+3]_16 chrV:19527760-19527840 3e-05 2_[+3]_70 chrV:11802589-11802669 3e-05 22_[+3]_50 chrIV:8028476-8028556 3.5e-05 41_[+3]_31 chrIV:8535123-8535203 3.5e-05 24_[+3]_48 chrIII:13767084-13767164 4.7e-05 10_[+3]_62 chrI:7659202-7659282 4.7e-05 26_[+3]_46 chrX:10084244-10084324 4.7e-05 16_[+3]_56 chrIII:5921428-5921508 4.7e-05 25_[+3]_47 chrII:12625852-12625932 4.7e-05 35_[+3]_37 chrV:13892678-13892758 7.7e-05 26_[+3]_46 chrII:8818430-8818510 7.7e-05 36_[+3]_36 chrIII:6144581-6144661 7.7e-05 29_[+3]_43 chrII:14838730-14838810 9.2e-05 44_[+3]_28 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CACGTGRH MEME-3 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF CACGTGRH width=8 seqs=20 chrV:13081259-13081339 ( 24) CACGTGGC 1 chrV:11799419-11799499 ( 22) CACGTGGC 1 chrX:5467441-5467521 ( 43) CACGTGGC 1 chrIV:8949781-8949861 ( 19) CACGTGGT 1 chrV:1438989-1439069 ( 22) CACGTGGT 1 chrIII:8739311-8739391 ( 28) CACGTGGG 1 chrIII:8732093-8732173 ( 57) CACGTGGG 1 chrV:19527760-19527840 ( 3) CACGTGGA 1 chrV:11802589-11802669 ( 23) CACGTGGA 1 chrIV:8028476-8028556 ( 42) CACGTGCC 1 chrIV:8535123-8535203 ( 25) CACGTGCC 1 chrIII:13767084-13767164 ( 11) CACGTGAT 1 chrI:7659202-7659282 ( 27) CACGTGAT 1 chrX:10084244-10084324 ( 17) CACGTGAT 1 chrIII:5921428-5921508 ( 26) CACGTGAT 1 chrII:12625852-12625932 ( 36) CACGTGAT 1 chrV:13892678-13892758 ( 27) CACGTGAA 1 chrII:8818430-8818510 ( 37) CACGTGCG 1 chrIII:6144581-6144661 ( 30) CACGTGAA 1 chrII:14838730-14838810 ( 45) CATGTGGC 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CACGTGRH MEME-3 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 10.0839 E= 1.6e+000 -1097 241 -1097 -1097 168 -1097 -1097 -1097 -1097 234 -1097 -264 -1097 -1097 240 -1097 -1097 -1097 -1097 168 -1097 -1097 240 -1097 17 -32 140 -1097 -64 68 -33 17 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CACGTGRH MEME-3 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 20 E= 1.6e+000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.950000 0.000000 0.050000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.350000 0.150000 0.500000 0.000000 0.200000 0.300000 0.150000 0.350000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CACGTGRH MEME-3 regular expression -------------------------------------------------------------------------------- CACGTG[GA][TCA] -------------------------------------------------------------------------------- Time 13.87 secs. ******************************************************************************** ******************************************************************************** MOTIF GCGCACGC MEME-4 width = 8 sites = 4 llr = 49 E-value = 2.4e+003 ******************************************************************************** -------------------------------------------------------------------------------- Motif GCGCACGC MEME-4 Description -------------------------------------------------------------------------------- Simplified A ::::a::: pos.-specific C 3a:a:a:a probability G 8:a:::a: matrix T :::::::: bits 2.4 *** *** 2.2 *** *** 1.9 *** *** 1.7 ******** Relative 1.4 ******** Entropy 1.2 ******** (17.7 bits) 1.0 ******** 0.7 ******** 0.5 ******** 0.2 ******** 0.0 -------- Multilevel GCGCACGC consensus C sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GCGCACGC MEME-4 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chrV:13380353-13380433 69 2.63e-06 CGGGAATGGT GCGCACGC GGTT chrII:5202086-5202166 70 2.63e-06 CATCCAAAAT GCGCACGC GAG chrII:162320-162400 59 2.63e-06 CGGTCCTTGC GCGCACGC AGTACTGATA chrII:7405429-7405509 71 5.25e-06 GAAATCGTTG CCGCACGC TT -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GCGCACGC MEME-4 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chrV:13380353-13380433 2.6e-06 68_[+4]_4 chrII:5202086-5202166 2.6e-06 69_[+4]_3 chrII:162320-162400 2.6e-06 58_[+4]_14 chrII:7405429-7405509 5.2e-06 70_[+4]_2 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GCGCACGC MEME-4 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF GCGCACGC width=8 seqs=4 chrV:13380353-13380433 ( 69) GCGCACGC 1 chrII:5202086-5202166 ( 70) GCGCACGC 1 chrII:162320-162400 ( 59) GCGCACGC 1 chrII:7405429-7405509 ( 71) CCGCACGC 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GCGCACGC MEME-4 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 12.1553 E= 2.4e+003 -865 41 199 -865 -865 241 -865 -865 -865 -865 240 -865 -865 241 -865 -865 168 -865 -865 -865 -865 241 -865 -865 -865 -865 240 -865 -865 241 -865 -865 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GCGCACGC MEME-4 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 4 E= 2.4e+003 0.000000 0.250000 0.750000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GCGCACGC MEME-4 regular expression -------------------------------------------------------------------------------- [GC]CGCACGC -------------------------------------------------------------------------------- Time 17.48 secs. ******************************************************************************** ******************************************************************************** MOTIF RAGAGAGR MEME-5 width = 8 sites = 36 llr = 293 E-value = 6.9e+000 ******************************************************************************** -------------------------------------------------------------------------------- Motif RAGAGAGR MEME-5 Description -------------------------------------------------------------------------------- Simplified A 58:a:a35 pos.-specific C :1::1::1 probability G 41a:9:75 matrix T 1::::::: bits 2.4 * 2.2 * * 1.9 * * 1.7 **** Relative 1.4 ***** Entropy 1.2 ***** (11.8 bits) 1.0 ****** 0.7 ******** 0.5 ******** 0.2 ******** 0.0 -------- Multilevel AAGAGAGA consensus G AG sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif RAGAGAGR MEME-5 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chrII:6619147-6619227 18 7.32e-06 TGGTCTTGTC GAGAGAGG ATGGATACCG chrI:9541027-9541107 12 7.32e-06 GAGAGAGTGA GAGAGAGG CAGAGAGGCG chrV:8426867-8426947 27 7.32e-06 TCAGAAACGA GAGAGAGG GAAGAGTTTC chrX:12425623-12425703 27 7.32e-06 GAAAAAGAGA GAGAGAGG GAGGAAGAAG chrIII:9454937-9455017 20 1.94e-05 TAGAAGAGAG AAGAGAGG TTGCAGAAAA chrIV:8042118-8042198 5 1.94e-05 ACTG AAGAGAGG AATAAGAGAG chrI:7659202-7659282 53 3.15e-05 CGTGTCGATT GAGAGAGA AGGCAAGAAA chrIII:746795-746875 32 3.15e-05 AAAAGAGTGA GAGAGAGA AACATCTGAA chrII:9586958-9587038 5 3.15e-05 AAAA GAGAGAGA ATGATAACTT chrII:5185389-5185469 41 5.15e-05 CTGAAAAAGA AAGAGAGA TGATTCTAAA chrV:10717402-10717482 29 5.15e-05 AAGATAGAGA AAGAGAGA TCACAGAGTG chrV:6736946-6737026 34 5.15e-05 TATAAAAAAT AAGAGAGA CAAAGATTGG chrIII:8867541-8867621 45 5.15e-05 GACGGAGGAA AAGAGAGA CGAACTATAT chrV:6365810-6365890 7 5.15e-05 gagaca aagagaga tagaaagaAC chrII:5283005-5283085 36 6.36e-05 AAAATGAGAC GAGAGAAG GTAGTTGTTA chrIV:13682908-13682988 59 6.36e-05 ATCTCTCACC GAGAGAAG ATATTATTTG chrIV:302359-302439 35 7.24e-05 AATGATGTAT GGGAGAGG AGGAGGGCTA chrI:8867676-8867756 34 9.24e-05 GGTGGGTCGG AAGAGAAG AGAATGGGGG chrII:8818430-8818510 66 9.24e-05 GCATTGTGAT AAGAGAAG TGGTGAT chrIV:5216448-5216528 43 9.24e-05 TTGAGAATTG AAGAGAAG AAAAAGACAA chrIV:8830711-8830791 25 1.12e-04 gatagacata gagagaaa cggcacgcag chrIII:10007184-10007264 21 1.12e-04 ATCAACAAGT GAGAGAAA ACCGGTTTAT chrII:7287257-7287337 68 1.20e-04 TTATGATTGT GAGAGAGC ATAGA chrX:2891517-2891597 44 1.34e-04 AGGCGGATAG ACGAGAGG ACAGAGAAAA chrIV:298852-298932 27 1.34e-04 TTGTACAGAA ACGAGAGG ACGACGAACA chrIV:6555554-6555634 53 1.34e-04 TTGAGAATAA AGGAGAGG TTTTTTTTGA chrV:5763976-5764056 7 1.49e-04 CTGATA GCGAGAGA GTGCAGAGAA chrIV:12716106-12716186 31 1.82e-04 GGGACAAAAT AAGAGAAA TTGTCTTCTG chrX:12844302-12844382 24 1.82e-04 AACTCACCGA AAGAGAAA GTTTCACGCA chrIV:9563245-9563325 70 1.82e-04 aacagtgatc aagagaaa aTT chrV:9925799-9925879 64 1.94e-04 CGTTTGTGAT AAGAGAGC GTTGAAATG chrIV:9647906-9647986 29 2.06e-04 CTGTGAGAAA TAGAGAGG ATTCATTGGG chrV:11676641-11676721 29 2.30e-04 TAGTCAGAAA AGGAGAGA ACACCTCAAT chrIV:13077942-13078022 29 2.37e-04 AGGAAAAAAA GAGACAGG AGAAATAGTC chrIII:7305131-7305211 63 2.57e-04 AAAAAAAGAG TAGAGAGA TAAAGAAGTT chrII:14838730-14838810 7 2.96e-04 CGTGCA GAGACAGA CTGATCTTTT -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif RAGAGAGR MEME-5 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chrII:6619147-6619227 7.3e-06 17_[+5]_55 chrI:9541027-9541107 7.3e-06 11_[+5]_61 chrV:8426867-8426947 7.3e-06 26_[+5]_46 chrX:12425623-12425703 7.3e-06 26_[+5]_46 chrIII:9454937-9455017 1.9e-05 19_[+5]_53 chrIV:8042118-8042198 1.9e-05 4_[+5]_68 chrI:7659202-7659282 3.2e-05 52_[+5]_20 chrIII:746795-746875 3.2e-05 31_[+5]_41 chrII:9586958-9587038 3.2e-05 4_[+5]_68 chrII:5185389-5185469 5.1e-05 40_[+5]_32 chrV:10717402-10717482 5.1e-05 28_[+5]_44 chrV:6736946-6737026 5.1e-05 33_[+5]_39 chrIII:8867541-8867621 5.1e-05 44_[+5]_28 chrV:6365810-6365890 5.1e-05 6_[+5]_66 chrII:5283005-5283085 6.4e-05 35_[+5]_37 chrIV:13682908-13682988 6.4e-05 58_[+5]_14 chrIV:302359-302439 7.2e-05 34_[+5]_38 chrI:8867676-8867756 9.2e-05 33_[+5]_39 chrII:8818430-8818510 9.2e-05 65_[+5]_7 chrIV:5216448-5216528 9.2e-05 42_[+5]_30 chrIV:8830711-8830791 0.00011 24_[+5]_48 chrIII:10007184-10007264 0.00011 20_[+5]_52 chrII:7287257-7287337 0.00012 67_[+5]_5 chrX:2891517-2891597 0.00013 43_[+5]_29 chrIV:298852-298932 0.00013 26_[+5]_46 chrIV:6555554-6555634 0.00013 52_[+5]_20 chrV:5763976-5764056 0.00015 6_[+5]_66 chrIV:12716106-12716186 0.00018 30_[+5]_42 chrX:12844302-12844382 0.00018 23_[+5]_49 chrIV:9563245-9563325 0.00018 69_[+5]_3 chrV:9925799-9925879 0.00019 63_[+5]_9 chrIV:9647906-9647986 0.00021 28_[+5]_44 chrV:11676641-11676721 0.00023 28_[+5]_44 chrIV:13077942-13078022 0.00024 28_[+5]_44 chrIII:7305131-7305211 0.00026 62_[+5]_10 chrII:14838730-14838810 0.0003 6_[+5]_66 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif RAGAGAGR MEME-5 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF RAGAGAGR width=8 seqs=36 chrII:6619147-6619227 ( 18) GAGAGAGG 1 chrI:9541027-9541107 ( 12) GAGAGAGG 1 chrV:8426867-8426947 ( 27) GAGAGAGG 1 chrX:12425623-12425703 ( 27) GAGAGAGG 1 chrIII:9454937-9455017 ( 20) AAGAGAGG 1 chrIV:8042118-8042198 ( 5) AAGAGAGG 1 chrI:7659202-7659282 ( 53) GAGAGAGA 1 chrIII:746795-746875 ( 32) GAGAGAGA 1 chrII:9586958-9587038 ( 5) GAGAGAGA 1 chrII:5185389-5185469 ( 41) AAGAGAGA 1 chrV:10717402-10717482 ( 29) AAGAGAGA 1 chrV:6736946-6737026 ( 34) AAGAGAGA 1 chrIII:8867541-8867621 ( 45) AAGAGAGA 1 chrV:6365810-6365890 ( 7) AAGAGAGA 1 chrII:5283005-5283085 ( 36) GAGAGAAG 1 chrIV:13682908-13682988 ( 59) GAGAGAAG 1 chrIV:302359-302439 ( 35) GGGAGAGG 1 chrI:8867676-8867756 ( 34) AAGAGAAG 1 chrII:8818430-8818510 ( 66) AAGAGAAG 1 chrIV:5216448-5216528 ( 43) AAGAGAAG 1 chrIV:8830711-8830791 ( 25) GAGAGAAA 1 chrIII:10007184-10007264 ( 21) GAGAGAAA 1 chrII:7287257-7287337 ( 68) GAGAGAGC 1 chrX:2891517-2891597 ( 44) ACGAGAGG 1 chrIV:298852-298932 ( 27) ACGAGAGG 1 chrIV:6555554-6555634 ( 53) AGGAGAGG 1 chrV:5763976-5764056 ( 7) GCGAGAGA 1 chrIV:12716106-12716186 ( 31) AAGAGAAA 1 chrX:12844302-12844382 ( 24) AAGAGAAA 1 chrIV:9563245-9563325 ( 70) AAGAGAAA 1 chrV:9925799-9925879 ( 64) AAGAGAGC 1 chrIV:9647906-9647986 ( 29) TAGAGAGG 1 chrV:11676641-11676721 ( 29) AGGAGAGA 1 chrIV:13077942-13078022 ( 29) GAGACAGG 1 chrIII:7305131-7305211 ( 63) TAGAGAGA 1 chrII:14838730-14838810 ( 7) GAGACAGA 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif RAGAGAGR MEME-5 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 10.389 E= 6.9e+000 68 -1181 123 -249 142 -117 -118 -1181 -1181 -1181 240 -1181 168 -1181 -1181 -1181 -1181 -176 232 -1181 168 -1181 -1181 -1181 -17 -1181 193 -1181 60 -176 132 -1181 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif RAGAGAGR MEME-5 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 36 E= 6.9e+000 0.500000 0.000000 0.444444 0.055556 0.833333 0.083333 0.083333 0.000000 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.055556 0.944444 0.000000 1.000000 0.000000 0.000000 0.000000 0.277778 0.000000 0.722222 0.000000 0.472222 0.055556 0.472222 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif RAGAGAGR MEME-5 regular expression -------------------------------------------------------------------------------- [AG]AGAGA[GA][AG] -------------------------------------------------------------------------------- Time 20.98 secs. ******************************************************************************** ******************************************************************************** SUMMARY OF MOTIFS ******************************************************************************** -------------------------------------------------------------------------------- Combined block diagrams: non-overlapping sites with p-value < 0.0001 -------------------------------------------------------------------------------- SEQUENCE NAME COMBINED P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chrI:9538014-9538094 2.32e-02 80 chrIV:7178991-7179071 1.75e-01 80 chrII:10169044-10169124 7.06e-02 15_[+2(3.20e-05)]_57 chrI:10409707-10409787 1.50e-02 80 chrV:8406991-8407071 9.47e-01 80 chrIV:6555554-6555634 7.30e-03 80 chrV:19612155-19612235 1.49e-02 80 chrX:10639570-10639650 7.92e-02 80 chrV:11087308-11087388 6.26e-01 80 chrIV:9563245-9563325 1.23e-02 49_[+1(6.57e-05)]_23 chrV:6652284-6652364 5.80e-01 80 chrII:5049404-5049484 6.45e-02 80 chrIV:9112124-9112204 2.63e-01 62_[+2(5.13e-05)]_10 chrIV:13682908-13682988 1.05e-01 58_[+5(6.36e-05)]_14 chrIV:4795215-4795295 4.78e-01 80 chrIV:11914889-11914969 1.98e-01 80 chrV:10886559-10886639 1.37e-01 71_[+2(9.00e-05)]_1 chrI:8869176-8869256 1.29e-02 59_[+1(6.57e-05)]_13 chrII:6562289-6562369 1.45e-01 80 chrIV:17474226-17474306 1.43e-01 80 chrX:2593001-2593081 3.72e-01 80 chrIV:13079229-13079309 2.38e-01 80 chrV:6365810-6365890 6.61e-03 6_[+5(5.15e-05)]_66 chrIV:12110255-12110335 8.02e-01 80 chrV:8383911-8383991 1.21e-01 80 chrIII:154335-154415 7.26e-01 80 chrIII:3104733-3104813 1.62e-02 80 chrV:11676641-11676721 2.08e-02 62_[+1(6.57e-05)]_10 chrIV:8979962-8980042 2.77e-01 80 chrV:8026512-8026592 1.40e-02 19_[+3(7.72e-05)]_53 chrIII:7203223-7203303 5.10e-01 80 chrIV:1718242-1718322 2.26e-01 80 chrV:20648993-20649073 2.35e-01 19_[+2(5.13e-05)]_53 chrIV:9051886-9051966 3.15e-01 80 chrII:5283005-5283085 1.43e-02 35_[+5(6.36e-05)]_37 chrIV:302359-302439 1.43e-01 34_[+5(7.24e-05)]_38 chrIII:7020950-7021030 4.92e-01 80 chrIV:5216448-5216528 4.15e-02 42_[+5(9.24e-05)]_30 chrIV:12400102-12400182 4.74e-01 80 chrV:4965138-4965218 1.54e-01 80 chrI:3530989-3531069 2.32e-01 80 chrIV:11901361-11901441 8.02e-01 80 chrV:13085380-13085460 8.23e-02 80 chrIV:9634114-9634194 2.80e-01 80 chrV:14660760-14660840 1.21e-02 80 chrIII:9389450-9389530 6.12e-03 66_[+1(6.57e-05)]_6 chrV:5823169-5823249 4.22e-01 80 chrII:14489581-14489661 1.72e-01 80 chrV:12301169-12301249 1.53e-02 80 chrX:11720179-11720259 5.81e-03 42_[+1(6.57e-05)]_30 chrV:6429999-6430079 8.18e-01 80 chrIII:8504282-8504362 1.27e-03 41_[+2(5.13e-05)]_31 chrIII:6144581-6144661 6.48e-02 29_[+3(7.72e-05)]_43 chrIII:6509580-6509660 2.67e-01 80 chrV:8449349-8449429 3.52e-02 32_[+2(9.00e-05)]_40 chrII:6026774-6026854 5.10e-01 80 chrIII:8867541-8867621 2.68e-02 44_[+5(5.15e-05)]_28 chrV:20712466-20712546 2.80e-02 80 chrIV:11211716-11211796 9.99e-01 80 chrII:10019762-10019842 5.48e-02 52_[+1(6.57e-05)]_20 chrX:9527964-9528044 5.58e-01 80 chrV:8655148-8655228 6.36e-02 80 chrV:13202345-13202425 1.70e-03 43_[+5(5.15e-05)]_29 chrV:4911652-4911732 1.30e-02 80 chrIII:7305131-7305211 1.47e-03 80 chrII:8818430-8818510 8.82e-03 36_[+3(7.72e-05)]_21_[+5(9.24e-05)]_\ 7 chrV:8768663-8768743 9.72e-01 80 chrII:8440856-8440936 5.02e-01 80 chrII:7631337-7631417 2.88e-01 80 chrIII:6422145-6422225 9.81e-01 80 chrIII:12842990-12843070 5.63e-01 80 chrIV:8528605-8528685 1.35e-02 80 chrII:1103854-1103934 9.72e-01 80 chrX:15161245-15161325 1.50e-01 80 chrII:12549867-12549947 7.03e-01 80 chrIV:14414396-14414476 1.14e-01 80 chrII:9753196-9753276 2.23e-02 53_[+1(6.57e-05)]_19 chrX:15373414-15373494 2.26e-01 80 chrIV:11092807-11092887 1.82e-01 80 chrX:12425623-12425703 1.46e-02 26_[+5(7.32e-06)]_46 chrV:8426867-8426947 2.97e-04 26_[+5(7.32e-06)]_46 chrII:4881856-4881936 9.62e-02 80 chrIII:8732093-8732173 1.09e-02 56_[+3(1.59e-05)]_16 chrI:4329091-4329171 7.53e-01 80 chrII:12625852-12625932 3.47e-02 35_[+3(4.66e-05)]_37 chrII:4387956-4388036 1.56e-01 80 chrIV:103003-103083 7.56e-01 80 chrII:5886118-5886198 2.18e-01 80 chrIV:8042118-8042198 2.16e-02 4_[+5(1.94e-05)]_68 chrV:9925799-9925879 2.04e-01 80 chrIV:6654032-6654112 6.34e-01 80 chrX:11393160-11393240 5.63e-01 80 chrIII:2169613-2169693 4.99e-02 80 chrX:11452263-11452343 2.29e-01 14_[+1(6.57e-05)]_58 chrII:9586958-9587038 5.28e-02 4_[+5(3.15e-05)]_68 chrI:9541027-9541107 4.65e-02 11_[+5(7.32e-06)]_61 chrIV:10782140-10782220 3.10e-01 80 chrX:13165738-13165818 3.09e-01 44_[+2(7.06e-05)]_28 chrII:8568943-8569023 4.49e-03 15_[+2(9.00e-05)]_57 chrIV:10216318-10216398 7.66e-01 80 chrIV:7530485-7530565 6.44e-01 80 chrV:13892678-13892758 9.01e-02 26_[+3(7.72e-05)]_46 chrX:9147172-9147252 6.09e-01 80 chrIII:746795-746875 1.49e-02 29_[+5(3.15e-05)]_43 chrIII:10007184-10007264 5.75e-02 80 chrX:12844302-12844382 7.38e-02 80 chrIII:10985756-10985836 2.03e-02 1_[+2(3.20e-05)]_71 chrII:3030326-3030406 3.31e-01 80 chrII:5572234-5572314 1.81e-01 80 chrV:13377215-13377295 5.45e-01 80 chrI:3085338-3085418 3.99e-01 80 chrIV:5605252-5605332 9.34e-01 80 chrII:12425977-12426057 1.74e-01 80 chrIII:8739311-8739391 5.30e-04 27_[+3(1.59e-05)]_45 chrIV:15395478-15395558 1.26e-01 25_[+2(3.20e-05)]_47 chrIII:6510685-6510765 3.72e-02 80 chrIII:7201486-7201566 1.71e-01 80 chrI:6210037-6210117 9.00e-02 80 chrI:3297177-3297257 2.75e-01 80 chrM:13159-13239 7.35e-01 80 chrI:8852534-8852614 3.24e-01 80 chrV:14510829-14510909 1.25e-01 13_[+2(5.13e-05)]_[+2(5.13e-05)]_35_\ [+2(3.20e-05)]_8 chrV:381370-381450 2.18e-01 80 chrV:11534658-11534738 3.82e-01 80 chrII:6619147-6619227 3.99e-02 17_[+5(7.32e-06)]_55 chrII:4599034-4599114 9.33e-02 30_[+2(5.13e-05)]_42 chrII:10390560-10390640 4.18e-02 53_[+2(9.00e-05)]_19 chrI:7661321-7661401 2.36e-01 80 chrV:14368335-14368415 1.60e-02 80 chrI:6997825-6997905 4.44e-03 37_[+1(6.57e-05)]_35 chrIV:9647906-9647986 5.49e-02 80 chrIV:10631126-10631206 7.47e-02 80 chrIII:8987046-8987126 3.11e-01 5_[+2(5.13e-05)]_67 chrI:8867676-8867756 4.44e-02 33_[+5(9.24e-05)]_39 chrV:4918874-4918954 2.33e-01 80 chrIV:9868048-9868128 7.60e-01 80 chrV:4908714-4908794 3.93e-01 80 chrII:14838730-14838810 1.24e-02 44_[+3(9.16e-05)]_28 chrV:11802589-11802669 5.86e-03 22_[+3(3.03e-05)]_50 chrV:8651490-8651570 5.52e-01 80 chrV:12353320-12353400 6.11e-01 80 chrIV:298852-298932 1.46e-02 80 chrV:13378062-13378142 1.03e-02 80 chrIV:8864848-8864928 9.65e-01 80 chrII:4855993-4856073 8.04e-01 80 chrIV:10617080-10617160 6.62e-01 80 chrIII:7199775-7199855 2.91e-01 80 chrIV:8535123-8535203 2.67e-02 24_[+3(3.47e-05)]_48 chrV:5832950-5833030 6.21e-02 71_[+1(6.57e-05)]_1 chrX:5467441-5467521 4.47e-03 42_[+3(4.35e-06)]_30 chrII:13681224-13681304 1.25e-04 9_[+1(6.57e-05)]_17_[+2(7.06e-05)]_\ 38 chrII:7405429-7405509 2.62e-02 70_[+4(5.25e-06)]_2 chrII:301196-301276 1.14e-01 62_[+2(9.00e-05)]_10 chrII:5333750-5333830 8.54e-02 80 chrIII:3309087-3309167 5.31e-02 80 chrI:7087425-7087505 7.18e-01 80 chrV:11147764-11147844 7.81e-01 80 chrM:182-262 4.68e-01 80 chrX:4132501-4132581 1.76e-01 80 chrI:7575626-7575706 4.84e-01 80 chrX:12759782-12759862 6.30e-01 80 chrV:18346226-18346306 1.54e-01 80 chrII:6849525-6849605 7.77e-02 25_[+2(9.00e-05)]_47 chrIII:5920135-5920215 3.10e-01 80 chrIV:8026548-8026628 2.91e-01 80 chrV:10860020-10860100 3.42e-02 80 chrII:162320-162400 2.88e-03 58_[+4(2.63e-06)]_14 chrV:17714505-17714585 7.46e-01 80 chrV:10371371-10371451 6.66e-01 80 chrIV:10855342-10855422 2.55e-01 80 chrV:6994123-6994203 2.69e-01 80 chrV:10423517-10423597 1.45e-01 80 chrIII:9454937-9455017 6.74e-03 19_[+5(1.94e-05)]_5_[+1(6.57e-05)]_\ 40 chrX:5628633-5628713 2.20e-01 80 chrII:7528423-7528503 3.23e-01 80 chrV:10938902-10938982 4.48e-01 80 chrIII:9500430-9500510 1.23e-01 27_[+2(5.13e-05)]_45 chrV:6247649-6247729 2.85e-01 80 chrIV:8032287-8032367 5.38e-01 80 chrII:12980365-12980445 1.99e-01 80 chrIII:3875631-3875711 8.20e-01 80 chrIV:11491504-11491584 4.36e-04 80 chrV:3193261-3193341 3.63e-02 28_[+1(6.57e-05)]_44 chrI:9168575-9168655 3.09e-01 80 chrIII:5921428-5921508 9.54e-04 10_[+1(6.57e-05)]_7_[+3(4.66e-05)]_\ 47 chrV:6736946-6737026 1.59e-01 33_[+5(5.15e-05)]_39 chrV:11799419-11799499 2.24e-02 21_[+3(4.35e-06)]_51 chrV:1438989-1439069 5.72e-03 21_[+3(1.16e-05)]_51 chrIV:9672536-9672616 2.22e-01 80 chrV:9160845-9160925 2.44e-02 80 chrV:10293144-10293224 3.14e-03 67_[+2(7.06e-05)]_5 chrV:8403253-8403333 5.39e-02 80 chrX:10689863-10689943 4.88e-01 80 chrII:2378697-2378777 3.89e-01 80 chrI:10758158-10758238 4.31e-01 80 chrII:13954308-13954388 4.20e-01 80 chrV:5393161-5393241 6.29e-01 80 chrV:5763976-5764056 1.34e-02 80 chrV:11803594-11803674 2.66e-01 80 chrV:9633386-9633466 2.66e-02 80 chrV:15880797-15880877 9.77e-01 80 chrII:10543508-10543588 1.66e-02 80 chrIV:9516965-9517045 1.92e-01 80 chrV:10717402-10717482 1.92e-05 1_[+4(8.78e-05)]_[+4(8.78e-05)]_11_\ [+5(5.15e-05)]_44 chrIV:247726-247806 8.34e-02 80 chrV:9085994-9086074 9.73e-01 80 chrIII:9269233-9269313 3.35e-01 80 chrII:7287257-7287337 6.40e-02 80 chrII:6822491-6822571 5.79e-01 80 chrIII:5550428-5550508 3.40e-01 80 chrI:4804743-4804823 1.74e-01 80 chrV:5768353-5768433 3.13e-01 80 chrIII:6148475-6148555 9.62e-01 80 chrII:5185389-5185469 2.29e-02 40_[+5(5.15e-05)]_32 chrM:7664-7744 9.99e-01 80 chrX:3819281-3819361 6.36e-02 80 chrII:5320350-5320430 9.22e-01 80 chrIV:3653583-3653663 3.31e-01 80 chrIII:3029972-3030052 3.27e-02 80 chrV:14505883-14505963 3.40e-01 80 chrX:10084244-10084324 5.93e-02 16_[+3(4.66e-05)]_56 chrII:5202086-5202166 2.19e-03 69_[+4(2.63e-06)]_3 chrV:19527760-19527840 3.78e-02 2_[+3(3.03e-05)]_70 chrII:8222787-8222867 7.44e-02 80 chrII:13679991-13680071 1.63e-01 80 chrIV:12716106-12716186 1.97e-02 80 chrV:13081259-13081339 3.66e-03 23_[+3(4.35e-06)]_49 chrIV:8949781-8949861 4.99e-03 18_[+3(1.16e-05)]_54 chrM:8541-8621 9.36e-01 80 chrV:13380353-13380433 4.11e-03 68_[+4(2.63e-06)]_4 chrIV:8530709-8530789 5.70e-02 80 chrIV:11897849-11897929 2.39e-01 80 chrII:7059352-7059432 1.17e-02 55_[+5(5.15e-05)]_17 chrII:7777373-7777453 3.98e-01 80 chrIV:13919363-13919443 5.34e-02 80 chrIV:8028476-8028556 6.44e-03 41_[+3(3.47e-05)]_31 chrX:11727901-11727981 4.73e-01 80 chrM:1751-1831 9.28e-01 80 chrIV:296937-297017 8.56e-01 80 chrII:6327505-6327585 3.32e-01 80 chrX:17063846-17063926 3.08e-01 80 chrI:7659202-7659282 5.16e-05 26_[+3(4.66e-05)]_18_[+5(3.15e-05)]_\ 20 chrIV:8830711-8830791 4.76e-03 80 chrIV:13077942-13078022 1.14e-02 12_[+1(6.57e-05)]_60 chrIII:4494726-4494806 2.70e-02 80 chrII:9128338-9128418 7.62e-02 80 chrX:2891517-2891597 5.12e-03 80 chrV:6323056-6323136 2.87e-01 80 chrIII:12849299-12849379 5.33e-01 80 chrIII:13767084-13767164 4.03e-02 10_[+3(4.66e-05)]_62 -------------------------------------------------------------------------------- ******************************************************************************** ******************************************************************************** Stopped because requested number of motifs (5) found. ******************************************************************************** CPU: c22n10.farnam.hpc.yale.internal ********************************************************************************