******************************************************************************** MEME - Motif discovery tool ******************************************************************************** MEME version 5.3.3 (Release date: Sun Feb 7 15:39:52 2021 -0800) For further information on how to interpret these results please access https://meme-suite.org/meme. To get a copy of the MEME Suite software please access https://meme-suite.org. ******************************************************************************** ******************************************************************************** REFERENCE ******************************************************************************** If you use this program in your research, please cite: Timothy L. Bailey and Charles Elkan, "Fitting a mixture model by expectation maximization to discover motifs in biopolymers", Proceedings of the Second International Conference on Intelligent Systems for Molecular Biology, pp. 28-36, AAAI Press, Menlo Park, California, 1994. ******************************************************************************** ******************************************************************************** TRAINING SET ******************************************************************************** PRIMARY SEQUENCES= ../result/final_prediction/K562/fasta/RankLinear0.6_40/ZNF395.fasta CONTROL SEQUENCES= --none-- ALPHABET= ACGT Sequence name Weight Length Sequence name Weight Length ------------- ------ ------ ------------- ------ ------ chr6:69345075-69345155 1.0000 80 chr6:5260889-5260969 1.0000 80 chr15:60314163-60314243 1.0000 80 chr3:14687937-14688017 1.0000 80 chr12:110841414-11084149 1.0000 80 chr19:35759269-35759349 1.0000 80 chr7:150756604-150756684 1.0000 80 chr17:44344179-44344259 1.0000 80 chr2:10091602-10091682 1.0000 80 chr19:11071624-11071704 1.0000 80 chr1:67526725-67526805 1.0000 80 chr1:40367567-40367647 1.0000 80 chr11:221059-221139 1.0000 80 chr11:13299075-13299155 1.0000 80 chr1:204141167-204141247 1.0000 80 chrX:15901580-15901660 1.0000 80 chr17:47154388-47154468 1.0000 80 chr11:71781039-71781119 1.0000 80 chr11:6271239-6271319 1.0000 80 chr16:1662262-1662342 1.0000 80 chr1:9884162-9884242 1.0000 80 chr8:29474732-29474812 1.0000 80 chr11:35358780-35358860 1.0000 80 chr7:130790749-130790829 1.0000 80 chr21:30164091-30164171 1.0000 80 chr17:40466092-40466172 1.0000 80 chr3:45147733-45147813 1.0000 80 chr10:15669685-15669765 1.0000 80 chr17:65989832-65989912 1.0000 80 chr17:47592699-47592779 1.0000 80 chr14:93042196-93042276 1.0000 80 chr15:29965596-29965676 1.0000 80 chr18:20048273-20048353 1.0000 80 chr19:48901984-48902064 1.0000 80 chr6:14077552-14077632 1.0000 80 chr19:7627865-7627945 1.0000 80 chr15:68193159-68193239 1.0000 80 chr8:20134427-20134507 1.0000 80 chr8:38854429-38854509 1.0000 80 chr6:37394925-37395005 1.0000 80 chr1:59762442-59762522 1.0000 80 chr3:194898960-194899040 1.0000 80 chr15:98536650-98536730 1.0000 80 chr4:54930854-54930934 1.0000 80 chr10:4868271-4868351 1.0000 80 chr8:74659085-74659165 1.0000 80 chr7:123633156-123633236 1.0000 80 chr20:34671186-34671266 1.0000 80 chr16:58467699-58467779 1.0000 80 chr1:223079711-223079791 1.0000 80 chr1:21113795-21113875 1.0000 80 chr8:145560353-145560433 1.0000 80 chr3:14688138-14688218 1.0000 80 chr7:116593765-116593845 1.0000 80 chr20:46768464-46768544 1.0000 80 chr8:94886427-94886507 1.0000 80 chr6:147770850-147770930 1.0000 80 chr4:1242465-1242545 1.0000 80 chr3:170075147-170075227 1.0000 80 chr7:143067411-143067491 1.0000 80 chr20:39577458-39577538 1.0000 80 chrX:3619590-3619670 1.0000 80 chr12:31771236-31771316 1.0000 80 chr9:114987090-114987170 1.0000 80 chr9:110438244-110438324 1.0000 80 chr21:46238028-46238108 1.0000 80 chr11:86648339-86648419 1.0000 80 chr2:10418613-10418693 1.0000 80 chr7:75473165-75473245 1.0000 80 chr2:68385026-68385106 1.0000 80 chr2:205219421-205219501 1.0000 80 chr1:18748628-18748708 1.0000 80 chr1:181143056-181143136 1.0000 80 chr14:103017351-10301743 1.0000 80 chr10:27530655-27530735 1.0000 80 chr11:78128954-78129034 1.0000 80 chr19:4400577-4400657 1.0000 80 chr20:35012574-35012654 1.0000 80 chr16:12704973-12705053 1.0000 80 chr8:142402137-142402217 1.0000 80 chr7:73867195-73867275 1.0000 80 chr1:247531178-247531258 1.0000 80 chr19:52290351-52290431 1.0000 80 chr1:10754812-10754892 1.0000 80 chr6:164758802-164758882 1.0000 80 chr3:125919527-125919607 1.0000 80 chr6:167368756-167368836 1.0000 80 chr16:77773536-77773616 1.0000 80 chr19:4342876-4342956 1.0000 80 chr6:7167204-7167284 1.0000 80 chr15:90325491-90325571 1.0000 80 chr9:132913305-132913385 1.0000 80 chr11:925759-925839 1.0000 80 chr11:9385613-9385693 1.0000 80 chr9:126872743-126872823 1.0000 80 chr1:26376538-26376618 1.0000 80 chr17:77007703-77007783 1.0000 80 chr1:55359158-55359238 1.0000 80 chr16:15581932-15582012 1.0000 80 chr1:110522352-110522432 1.0000 80 chr8:10847824-10847904 1.0000 80 chr1:222135848-222135928 1.0000 80 chr2:128685146-128685226 1.0000 80 chr3:127451786-127451866 1.0000 80 chr21:37700055-37700135 1.0000 80 chr8:98774862-98774942 1.0000 80 chr6:12023328-12023408 1.0000 80 chr17:13542252-13542332 1.0000 80 chr14:64830111-64830191 1.0000 80 chr19:50082618-50082698 1.0000 80 chr3:138129227-138129307 1.0000 80 chr2:102875175-102875255 1.0000 80 chr12:131847305-13184738 1.0000 80 chr12:121455844-12145592 1.0000 80 chr17:46903263-46903343 1.0000 80 chr4:79615503-79615583 1.0000 80 chr4:38939086-38939166 1.0000 80 chr1:31956197-31956277 1.0000 80 chrX:2420834-2420914 1.0000 80 chr8:111907144-111907224 1.0000 80 chr12:6717075-6717155 1.0000 80 chr15:64085292-64085372 1.0000 80 chr3:44482940-44483020 1.0000 80 chr9:101614428-101614508 1.0000 80 chr7:106437322-106437402 1.0000 80 chr12:132090122-13209020 1.0000 80 chr5:169514587-169514667 1.0000 80 chr3:156338148-156338228 1.0000 80 chr1:1545339-1545419 1.0000 80 chr2:47525076-47525156 1.0000 80 chr1:235116801-235116881 1.0000 80 chr7:158611325-158611405 1.0000 80 chr20:9006495-9006575 1.0000 80 chrX:67682119-67682199 1.0000 80 chr16:2264916-2264996 1.0000 80 chr7:127877307-127877387 1.0000 80 chr15:45876405-45876485 1.0000 80 chr14:31711905-31711985 1.0000 80 chr17:3907951-3908031 1.0000 80 chr2:9309966-9310046 1.0000 80 chr1:234614513-234614593 1.0000 80 chr22:29549306-29549386 1.0000 80 chr9:101558810-101558890 1.0000 80 chr11:63302449-63302529 1.0000 80 chr19:3133428-3133508 1.0000 80 chr14:103000327-10300040 1.0000 80 chr10:75939017-75939097 1.0000 80 chr21:38939238-38939318 1.0000 80 chr14:58765066-58765146 1.0000 80 chr20:1373821-1373901 1.0000 80 chr3:101362786-101362866 1.0000 80 chr20:30556315-30556395 1.0000 80 chr8:67341213-67341293 1.0000 80 chr6:27968251-27968331 1.0000 80 chr1:247538120-247538200 1.0000 80 chr16:68298357-68298437 1.0000 80 chr5:148533493-148533573 1.0000 80 chr10:124671563-12467164 1.0000 80 chr10:3933017-3933097 1.0000 80 chr1:229761891-229761971 1.0000 80 chr4:1872862-1872942 1.0000 80 chr12:127388132-12738821 1.0000 80 chr1:235752306-235752386 1.0000 80 chr15:89164562-89164642 1.0000 80 chr17:48526205-48526285 1.0000 80 chr1:223920408-223920488 1.0000 80 chr12:33099596-33099676 1.0000 80 chr9:131843205-131843285 1.0000 80 chr4:57566970-57567050 1.0000 80 chr2:69135668-69135748 1.0000 80 chr4:154458952-154459032 1.0000 80 chr2:231519571-231519651 1.0000 80 chr6:24668921-24669001 1.0000 80 chr16:10419931-10420011 1.0000 80 chr17:62409502-62409582 1.0000 80 chr2:152237302-152237382 1.0000 80 chr18:43742147-43742227 1.0000 80 chr17:4843209-4843289 1.0000 80 chr13:61158225-61158305 1.0000 80 chr4:74962375-74962455 1.0000 80 chr17:36762204-36762284 1.0000 80 chr3:72496533-72496613 1.0000 80 chr15:58644656-58644736 1.0000 80 chr11:100885507-10088558 1.0000 80 chr3:37865989-37866069 1.0000 80 chr1:12043684-12043764 1.0000 80 chr3:48699257-48699337 1.0000 80 chr11:97844213-97844293 1.0000 80 chr8:101514065-101514145 1.0000 80 chr22:24407592-24407672 1.0000 80 chr5:88179045-88179125 1.0000 80 chr9:136933178-136933258 1.0000 80 chr12:96476854-96476934 1.0000 80 chr1:212651651-212651731 1.0000 80 chr4:151959757-151959837 1.0000 80 chr16:15668327-15668407 1.0000 80 chr1:226297755-226297835 1.0000 80 chrX:62654800-62654880 1.0000 80 chr1:63833203-63833283 1.0000 80 chr16:46977399-46977479 1.0000 80 chr22:31742033-31742113 1.0000 80 chr17:37170404-37170484 1.0000 80 chr2:39377340-39377420 1.0000 80 chr12:76077831-76077911 1.0000 80 chr1:173640364-173640444 1.0000 80 chr17:77783983-77784063 1.0000 80 chr9:102064158-102064238 1.0000 80 chr4:185261027-185261107 1.0000 80 chr7:84451405-84451485 1.0000 80 chr7:22219179-22219259 1.0000 80 chr1:67395829-67395909 1.0000 80 chr16:87840470-87840550 1.0000 80 chr6:111140827-111140907 1.0000 80 chrX:109244498-109244578 1.0000 80 chr7:151623177-151623257 1.0000 80 chr16:1344206-1344286 1.0000 80 chr10:45906821-45906901 1.0000 80 chr7:156931430-156931510 1.0000 80 chr9:99183097-99183177 1.0000 80 chr21:34673092-34673172 1.0000 80 chr15:63519289-63519369 1.0000 80 chr13:64848826-64848906 1.0000 80 chr16:17684907-17684987 1.0000 80 chr1:1709984-1710064 1.0000 80 chr12:127393011-12739309 1.0000 80 chr11:70496566-70496646 1.0000 80 chr10:25247785-25247865 1.0000 80 chrX:40430920-40431000 1.0000 80 chr6:16214836-16214916 1.0000 80 chr17:43224647-43224727 1.0000 80 chr10:21822958-21823038 1.0000 80 chr6:158425136-158425216 1.0000 80 chr3:53389142-53389222 1.0000 80 chr9:128845116-128845196 1.0000 80 chr16:71918066-71918146 1.0000 80 chr6:158176305-158176385 1.0000 80 chr2:201991179-201991259 1.0000 80 chr3:45209074-45209154 1.0000 80 chr17:73179156-73179236 1.0000 80 chr3:193308478-193308558 1.0000 80 chr18:874367-874447 1.0000 80 chr1:234745953-234746033 1.0000 80 chr18:5296238-5296318 1.0000 80 chr16:20956257-20956337 1.0000 80 chr8:41676492-41676572 1.0000 80 chr3:99495999-99496079 1.0000 80 chr10:21368132-21368212 1.0000 80 chr20:49955690-49955770 1.0000 80 chr11:44552511-44552591 1.0000 80 chr7:30711617-30711697 1.0000 80 ******************************************************************************** ******************************************************************************** COMMAND LINE SUMMARY ******************************************************************************** This information can also be useful in the event you wish to report a problem with the MEME software. command: meme -oc ../result/final_prediction/K562/inference_raw/MEME/RankLinear0.6_40_ZNF395/ -dna -nmotifs 5 -w 8 -maxsize 250000 -nostatus ../result/final_prediction/K562/fasta/RankLinear0.6_40/ZNF395.fasta model: mod= zoops nmotifs= 5 evt= inf objective function: em= E-value of product of p-values starts= E-value of product of p-values strands: + width: minw= 8 maxw= 8 nsites: minsites= 2 maxsites= 250 wnsites= 0.8 theta: spmap= uni spfuzz= 0.5 em: prior= dirichlet b= 0.01 maxiter= 50 distance= 1e-05 trim: wg= 11 ws= 1 endgaps= yes data: n= 20000 N= 250 sample: seed= 0 hsfrac= 0 searchsize= 20000 norand= no csites= 1000 Letter frequencies in dataset: A 0.218 C 0.285 G 0.276 T 0.22 Background letter frequencies (from file dataset with add-one prior applied): A 0.219 C 0.285 G 0.276 T 0.22 Background model order: 0 ******************************************************************************** ******************************************************************************** MOTIF AAGATGGA MEME-1 width = 8 sites = 62 llr = 621 E-value = 1.3e-077 ******************************************************************************** -------------------------------------------------------------------------------- Motif AAGATGGA MEME-1 Description -------------------------------------------------------------------------------- Simplified A aa1a:::9 pos.-specific C :::::::: probability G ::9::aa: matrix T ::::a::: bits 2.2 * * 2.0 ** ** 1.8 ** ** ** 1.5 ** ***** Relative 1.3 ** ***** Entropy 1.1 ******** (14.5 bits) 0.9 ******** 0.7 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel AAGATGGA consensus sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAGATGGA MEME-1 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr3:99495999-99496079 16 1.06e-05 gcccctattc aagatgga gttgctctgg chr3:193308478-193308558 30 1.06e-05 ggtcagaagc aagatgga gtcaactatg chr2:201991179-201991259 16 1.06e-05 tgaaacagcc aagatgga gtctgtctgg chr6:158176305-158176385 3 1.06e-05 tc aagatgga gttgctctgg chrX:40430920-40431000 48 1.06e-05 agccccattc aagatgga gtcactctgg chr12:127393011-12739309 35 1.06e-05 ggacctattc aagatgga gtggcactgg chr10:45906821-45906901 21 1.06e-05 gcccctattc aagatgga gttgctgtgg chr16:1344206-1344286 40 1.06e-05 agccccattc aagatgga gttgctctgg chrX:109244498-109244578 28 1.06e-05 ggccctgttc aagatgga gtcgctctgg chr4:185261027-185261107 33 1.06e-05 gcctctgctc aagatgga gtcactctgg chr16:46977399-46977479 67 1.06e-05 gccctcattc aagatgga gtcact chr16:15668327-15668407 53 1.06e-05 ggttagaagc aagatgga gttgattagg chr4:74962375-74962455 32 1.06e-05 gcccctattc aagatgga gttgctctgg chr18:43742147-43742227 20 1.06e-05 gcccttattc aagatgga gtcgctctgg chr16:10419931-10420011 3 1.06e-05 tt aagatgga gttgctctgg chr4:154458952-154459032 4 1.06e-05 ttt aagatgga gttgctctgg chr1:223920408-223920488 13 1.06e-05 gctcttattc aagatgga gttgctctag chr12:127388132-12738821 3 1.06e-05 tt aagatgga gttgctcagg chr14:103000327-10300040 19 1.06e-05 gcccctgctc aagatgga gttgctctgg chr22:29549306-29549386 55 1.06e-05 gcccctattc aagatgga gtcgctctgt chr14:31711905-31711985 10 1.06e-05 cccctattt aagatgga gttgctctgg chr15:45876405-45876485 23 1.06e-05 agtcctattc aagatgga gttgctctgg chr12:132090122-13209020 26 1.06e-05 gcccctgttc aagatgga gtcattctgg chr7:106437322-106437402 37 1.06e-05 gcttctattc aagatgga gttgctccag chr9:101614428-101614508 17 1.06e-05 gcccctgttc aagatgga gttactgtgg chr3:44482940-44483020 46 1.06e-05 ttccctattc aagatgga gtcactctgg chr4:79615503-79615583 30 1.06e-05 ggttaaaggt aagatgga gttggttagg chr17:46903263-46903343 42 1.06e-05 gcccctattc aagatgga gtcactctgg chr12:131847305-13184738 20 1.06e-05 gtccttgttc aagatgga gtcactctgg chr3:138129227-138129307 1 1.06e-05 . aagatgga gttgctgtgg chr16:77773536-77773616 46 1.06e-05 gcccctattc aagatgga gttgctctgg chr7:73867195-73867275 25 1.06e-05 ggctggaagc aagatgga gtcagccacg chr2:205219421-205219501 11 1.06e-05 gtctttttct aagatgga gttacttatg chr7:75473165-75473245 13 1.06e-05 gccctcactc aagatgga gtcactctgg chr9:110438244-110438324 4 1.06e-05 ttc aagatgga gtcactctgg chr20:39577458-39577538 30 1.06e-05 gccgctattc aagatgga gttgctctgg chr6:147770850-147770930 68 1.06e-05 gcccccattc aagatgga gacat chr8:94886427-94886507 15 1.06e-05 ccccctattc aagatgga gtcactctag chr20:46768464-46768544 17 1.06e-05 gcccctattc aagatgga gttgctctgg chr7:123633156-123633236 24 1.06e-05 agccctattc aagatgga gtcactctgg chr15:68193159-68193239 39 1.06e-05 ggcactattc aagatgga gttgctctgg chr17:47154388-47154468 29 1.06e-05 gcacttattc aagatgga gtcgctctgg chr11:63302449-63302529 7 1.91e-05 TATTTC AAAATGGA GTCACTTACG chr1:1545339-1545419 55 1.91e-05 caaaccctga aaaatgga gccaggaggc chr19:50082618-50082698 1 1.91e-05 . aaaatgga gacactcatg chr12:31771236-31771316 22 1.91e-05 accaaaaatc aaaatgga gtcacccatg chr6:111140827-111140907 21 2.75e-05 tgggggcatc aagataga aatAACtgtc chr20:35012574-35012654 46 2.75e-05 CGTGGTGCTG AAGATAGA GAGGGTAGAG chr8:41676492-41676572 17 3.60e-05 gtaacaaagc aatatgga gtaactcaag chr13:64848826-64848906 35 3.60e-05 gaggtgaaac aatatgga gtaactcagg chr16:15581932-15582012 20 4.67e-05 gcccctattc aagatggt gttgttctgg chr15:60314163-60314243 6 4.67e-05 tactc aagatggt gtcgctccag chr6:12023328-12023408 14 6.05e-05 CTTAGGTTCC AAGATGGC AGCCATCTCT chr9:132913305-132913385 1 6.05e-05 . aagatggc gttgctctgg chr20:1373821-1373901 9 7.39e-05 GCCTCCGG AAGAGGGA CCGGAAGCCC chr1:247531178-247531258 49 7.39e-05 atatttgaac aagaggga ctccatcttg chr1:222135848-222135928 40 8.23e-05 gattttgggg aagatgaa ataacaactt chr7:84451405-84451485 32 9.33e-05 gcctctatac aacatgga gtcactctgg chr14:93042196-93042276 57 1.07e-04 acccctattc aagatggg ggtcactctg chr15:58644656-58644736 59 1.20e-04 ccctctatat gagatgga gtcactctgg chr1:31956197-31956277 32 1.34e-04 ccaggggaag cagatgga attaaaacat chr6:16214836-16214916 69 1.41e-04 tcaGGATGtg aaaataga aggt -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAGATGGA MEME-1 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr3:99495999-99496079 1.1e-05 15_[+1]_57 chr3:193308478-193308558 1.1e-05 29_[+1]_43 chr2:201991179-201991259 1.1e-05 15_[+1]_57 chr6:158176305-158176385 1.1e-05 2_[+1]_70 chrX:40430920-40431000 1.1e-05 47_[+1]_25 chr12:127393011-12739309 1.1e-05 34_[+1]_38 chr10:45906821-45906901 1.1e-05 20_[+1]_52 chr16:1344206-1344286 1.1e-05 39_[+1]_33 chrX:109244498-109244578 1.1e-05 27_[+1]_45 chr4:185261027-185261107 1.1e-05 32_[+1]_40 chr16:46977399-46977479 1.1e-05 66_[+1]_6 chr16:15668327-15668407 1.1e-05 52_[+1]_20 chr4:74962375-74962455 1.1e-05 31_[+1]_41 chr18:43742147-43742227 1.1e-05 19_[+1]_53 chr16:10419931-10420011 1.1e-05 2_[+1]_70 chr4:154458952-154459032 1.1e-05 3_[+1]_69 chr1:223920408-223920488 1.1e-05 12_[+1]_60 chr12:127388132-12738821 1.1e-05 2_[+1]_70 chr14:103000327-10300040 1.1e-05 18_[+1]_54 chr22:29549306-29549386 1.1e-05 54_[+1]_18 chr14:31711905-31711985 1.1e-05 9_[+1]_63 chr15:45876405-45876485 1.1e-05 22_[+1]_50 chr12:132090122-13209020 1.1e-05 25_[+1]_47 chr7:106437322-106437402 1.1e-05 36_[+1]_36 chr9:101614428-101614508 1.1e-05 16_[+1]_56 chr3:44482940-44483020 1.1e-05 45_[+1]_27 chr4:79615503-79615583 1.1e-05 29_[+1]_43 chr17:46903263-46903343 1.1e-05 41_[+1]_31 chr12:131847305-13184738 1.1e-05 19_[+1]_53 chr3:138129227-138129307 1.1e-05 [+1]_72 chr16:77773536-77773616 1.1e-05 45_[+1]_27 chr7:73867195-73867275 1.1e-05 24_[+1]_48 chr2:205219421-205219501 1.1e-05 10_[+1]_62 chr7:75473165-75473245 1.1e-05 12_[+1]_60 chr9:110438244-110438324 1.1e-05 3_[+1]_69 chr20:39577458-39577538 1.1e-05 29_[+1]_43 chr6:147770850-147770930 1.1e-05 67_[+1]_5 chr8:94886427-94886507 1.1e-05 14_[+1]_58 chr20:46768464-46768544 1.1e-05 16_[+1]_56 chr7:123633156-123633236 1.1e-05 23_[+1]_49 chr15:68193159-68193239 1.1e-05 38_[+1]_34 chr17:47154388-47154468 1.1e-05 28_[+1]_44 chr11:63302449-63302529 1.9e-05 6_[+1]_66 chr1:1545339-1545419 1.9e-05 54_[+1]_18 chr19:50082618-50082698 1.9e-05 [+1]_72 chr12:31771236-31771316 1.9e-05 21_[+1]_51 chr6:111140827-111140907 2.8e-05 20_[+1]_52 chr20:35012574-35012654 2.8e-05 45_[+1]_27 chr8:41676492-41676572 3.6e-05 16_[+1]_56 chr13:64848826-64848906 3.6e-05 34_[+1]_38 chr16:15581932-15582012 4.7e-05 19_[+1]_53 chr15:60314163-60314243 4.7e-05 5_[+1]_67 chr6:12023328-12023408 6.1e-05 13_[+1]_59 chr9:132913305-132913385 6.1e-05 [+1]_72 chr20:1373821-1373901 7.4e-05 8_[+1]_64 chr1:247531178-247531258 7.4e-05 48_[+1]_24 chr1:222135848-222135928 8.2e-05 39_[+1]_33 chr7:84451405-84451485 9.3e-05 31_[+1]_41 chr14:93042196-93042276 0.00011 56_[+1]_16 chr15:58644656-58644736 0.00012 58_[+1]_14 chr1:31956197-31956277 0.00013 31_[+1]_41 chr6:16214836-16214916 0.00014 68_[+1]_4 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAGATGGA MEME-1 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF AAGATGGA width=8 seqs=62 chr3:99495999-99496079 ( 16) AAGATGGA 1 chr3:193308478-193308558 ( 30) AAGATGGA 1 chr2:201991179-201991259 ( 16) AAGATGGA 1 chr6:158176305-158176385 ( 3) AAGATGGA 1 chrX:40430920-40431000 ( 48) AAGATGGA 1 chr12:127393011-12739309 ( 35) AAGATGGA 1 chr10:45906821-45906901 ( 21) AAGATGGA 1 chr16:1344206-1344286 ( 40) AAGATGGA 1 chrX:109244498-109244578 ( 28) AAGATGGA 1 chr4:185261027-185261107 ( 33) AAGATGGA 1 chr16:46977399-46977479 ( 67) AAGATGGA 1 chr16:15668327-15668407 ( 53) AAGATGGA 1 chr4:74962375-74962455 ( 32) AAGATGGA 1 chr18:43742147-43742227 ( 20) AAGATGGA 1 chr16:10419931-10420011 ( 3) AAGATGGA 1 chr4:154458952-154459032 ( 4) AAGATGGA 1 chr1:223920408-223920488 ( 13) AAGATGGA 1 chr12:127388132-12738821 ( 3) AAGATGGA 1 chr14:103000327-10300040 ( 19) AAGATGGA 1 chr22:29549306-29549386 ( 55) AAGATGGA 1 chr14:31711905-31711985 ( 10) AAGATGGA 1 chr15:45876405-45876485 ( 23) AAGATGGA 1 chr12:132090122-13209020 ( 26) AAGATGGA 1 chr7:106437322-106437402 ( 37) AAGATGGA 1 chr9:101614428-101614508 ( 17) AAGATGGA 1 chr3:44482940-44483020 ( 46) AAGATGGA 1 chr4:79615503-79615583 ( 30) AAGATGGA 1 chr17:46903263-46903343 ( 42) AAGATGGA 1 chr12:131847305-13184738 ( 20) AAGATGGA 1 chr3:138129227-138129307 ( 1) AAGATGGA 1 chr16:77773536-77773616 ( 46) AAGATGGA 1 chr7:73867195-73867275 ( 25) AAGATGGA 1 chr2:205219421-205219501 ( 11) AAGATGGA 1 chr7:75473165-75473245 ( 13) AAGATGGA 1 chr9:110438244-110438324 ( 4) AAGATGGA 1 chr20:39577458-39577538 ( 30) AAGATGGA 1 chr6:147770850-147770930 ( 68) AAGATGGA 1 chr8:94886427-94886507 ( 15) AAGATGGA 1 chr20:46768464-46768544 ( 17) AAGATGGA 1 chr7:123633156-123633236 ( 24) AAGATGGA 1 chr15:68193159-68193239 ( 39) AAGATGGA 1 chr17:47154388-47154468 ( 29) AAGATGGA 1 chr11:63302449-63302529 ( 7) AAAATGGA 1 chr1:1545339-1545419 ( 55) AAAATGGA 1 chr19:50082618-50082698 ( 1) AAAATGGA 1 chr12:31771236-31771316 ( 22) AAAATGGA 1 chr6:111140827-111140907 ( 21) AAGATAGA 1 chr20:35012574-35012654 ( 46) AAGATAGA 1 chr8:41676492-41676572 ( 17) AATATGGA 1 chr13:64848826-64848906 ( 35) AATATGGA 1 chr16:15581932-15582012 ( 20) AAGATGGT 1 chr15:60314163-60314243 ( 6) AAGATGGT 1 chr6:12023328-12023408 ( 14) AAGATGGC 1 chr9:132913305-132913385 ( 1) AAGATGGC 1 chr20:1373821-1373901 ( 9) AAGAGGGA 1 chr1:247531178-247531258 ( 49) AAGAGGGA 1 chr1:222135848-222135928 ( 40) AAGATGAA 1 chr7:84451405-84451485 ( 32) AACATGGA 1 chr14:93042196-93042276 ( 57) AAGATGGG 1 chr15:58644656-58644736 ( 59) GAGATGGA 1 chr1:31956197-31956277 ( 32) CAGATGGA 1 chr6:16214836-16214916 ( 69) AAAATAGA 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAGATGGA MEME-1 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 8.90467 E= 1.3e-077 215 -414 -409 -1260 219 -1260 -1260 -1260 -144 -414 166 -277 219 -1260 -1260 -1260 -1260 -1260 -310 214 -217 -1260 178 -1260 -376 -1260 183 -1260 207 -314 -409 -277 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAGATGGA MEME-1 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 62 E= 1.3e-077 0.967742 0.016129 0.016129 0.000000 1.000000 0.000000 0.000000 0.000000 0.080645 0.016129 0.870968 0.032258 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.032258 0.967742 0.048387 0.000000 0.951613 0.000000 0.016129 0.000000 0.983871 0.000000 0.919355 0.032258 0.016129 0.032258 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAGATGGA MEME-1 regular expression -------------------------------------------------------------------------------- AAGATGGA -------------------------------------------------------------------------------- Time 4.87 secs. ******************************************************************************** ******************************************************************************** MOTIF TCCATCTT MEME-2 width = 8 sites = 57 llr = 568 E-value = 2.7e-066 ******************************************************************************** -------------------------------------------------------------------------------- Motif TCCATCTT MEME-2 Description -------------------------------------------------------------------------------- Simplified A :::a:::: pos.-specific C :aa::6:: probability G :::::1:: matrix T 9:::a3aa bits 2.2 ** * 2.0 ** ** 1.8 * *** ** 1.5 ***** ** Relative 1.3 ***** ** Entropy 1.1 ***** ** (14.4 bits) 0.9 ***** ** 0.7 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel TCCATCTT consensus T sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCCATCTT MEME-2 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr16:20956257-20956337 66 1.19e-05 ccagagcaac tccatctt gtatagg chr6:158425136-158425216 72 1.19e-05 ccagagcgac tccatctt g chr21:34673092-34673172 42 1.19e-05 ccagagcgac tccatctt gaagaggggc chr7:151623177-151623257 58 1.19e-05 ctcaagtgac tccatctt cctgagcctc chr6:111140827-111140907 60 1.19e-05 ccacagtgac tccatctt gaatagggta chr9:102064158-102064238 63 1.19e-05 ccagagggac tccatctt gaacaggggc chr4:151959757-151959837 34 1.19e-05 ccagagcgac tccatctt gaataggggc chr8:101514065-101514145 61 1.19e-05 catgagtgac tccatctt ggtttggtct chr13:61158225-61158305 15 1.19e-05 cctcactgac tccatctt gcttctaacc chr2:231519571-231519651 33 1.19e-05 ccacagcaac tccatctt gattaggagc chr10:3933017-3933097 32 1.19e-05 ctagggcgac tccatctt aaatagagag chr10:75939017-75939097 63 1.19e-05 ccagagcgac tccatctt gaatagggtc chrX:67682119-67682199 59 1.19e-05 ccagagtgac tccatctt taataggtgc chr20:9006495-9006575 28 1.19e-05 cctaaccaac tccatctt gcttctaacc chr2:47525076-47525156 49 1.19e-05 ccagagtgac tccatctt aagtaggggc chr15:64085292-64085372 60 1.19e-05 ccagagcaac tccatctt gagtagggac chrX:2420834-2420914 62 1.19e-05 aatcatcaac tccatctt aaaaaccagg chr14:64830111-64830191 59 1.19e-05 ccagagcaac tccatctt gaataggggc chr8:98774862-98774942 32 1.19e-05 ccacagtgac tccatctt gaataggggc chr3:127451786-127451866 42 1.19e-05 ccagagcaac tccatctt gaacgggggc chr15:90325491-90325571 56 1.19e-05 ccagagcgat tccatctt gaataggggc chr6:164758802-164758882 71 1.19e-05 ccagagcgac tccatctt ga chr1:247531178-247531258 58 1.19e-05 caagagggac tccatctt gaagatgggc chr16:12704973-12705053 59 1.19e-05 ccagagcaac tccatctt gggtaggagc chr1:181143056-181143136 44 1.19e-05 ccagagtgac tccatctt gaataggggc chr1:18748628-18748708 73 1.19e-05 caagagtgac tccatctt chrX:3619590-3619670 55 1.19e-05 ccagagcaac tccatctt gaagaggagc chr7:143067411-143067491 70 1.19e-05 ccagagcaac tccatctt gaa chr1:223079711-223079791 25 1.19e-05 ccagagcaac tccatctt aaataggggc chr20:34671186-34671266 28 1.19e-05 ccagagcaac tccatctt gagtaggtgc chr6:14077552-14077632 38 1.19e-05 ccggagagac tccatctt gaatagggct chr21:30164091-30164171 13 1.19e-05 ccagagtgac tccatctt gaatagggga chr8:29474732-29474812 51 1.19e-05 ccagagcaac tccatctt gaatagggac chr9:99183097-99183177 61 2.10e-05 ccagagcaac tccatttt aaaaaggagc chr1:212651651-212651731 33 2.10e-05 cacgagtgac tccatttt ggcttggtct chr2:152237302-152237382 42 2.10e-05 catgagtgac tccatttt ggtttggtct chr17:48526205-48526285 51 2.10e-05 cttacctggc tccatttt gtcagggttt chr12:121455844-12145592 30 2.10e-05 cataagtgac tccatttt gatactgata chr21:37700055-37700135 51 2.10e-05 catgggtgac tccatttt gatttttagt chr2:128685146-128685226 33 2.10e-05 catgagtgac tccatttt ggtttggtct chr1:55359158-55359238 40 2.10e-05 cattagtgac tccatttt gatgctgaca chr1:26376538-26376618 29 2.10e-05 ctgcctcgct tccatttt ccttccctct chr14:103017351-10301743 51 2.10e-05 ccagagcaac tccatttt gaataggggc chr1:204141167-204141247 33 2.10e-05 catgactgac tccatttt gcctctgacc chr1:67526725-67526805 22 2.10e-05 cttctctagc tccatttt gctagggttt chr11:97844213-97844293 45 3.25e-05 cctgagttac tccatgtt gtttatctct chr19:52290351-52290431 48 3.25e-05 ccagagcaac tccatgtt gaatagtagc chr8:20134427-20134507 53 3.25e-05 ccagagcaac tccatgtt gaataggggc chr12:33099596-33099676 30 4.17e-05 ccagagtgac tccatatt gaataggggc chr3:125919527-125919607 51 4.17e-05 catgagtgac tccatatt ggcttggtct chr17:13542252-13542332 71 6.27e-05 ccaaagcgac accatctt ga chr17:77007703-77007783 49 6.27e-05 ccagagcaac accatctt gaataagggc chr2:39377340-39377420 49 7.76e-05 catgagggaa gccatctt gatgtttcag chr18:874367-874447 64 8.46e-05 aggtttcagc ttcatttt acccagctc chr16:1344206-1344286 18 8.46e-05 aggtctcagc ttcatttt acgcagcccc chr6:5260889-5260969 73 1.05e-04 ACTGGAGGCT GCCATTTT chr12:76077831-76077911 55 1.20e-04 ccagagcaac tccatctg gaataggagc -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCCATCTT MEME-2 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr16:20956257-20956337 1.2e-05 65_[+2]_7 chr6:158425136-158425216 1.2e-05 71_[+2]_1 chr21:34673092-34673172 1.2e-05 41_[+2]_31 chr7:151623177-151623257 1.2e-05 57_[+2]_15 chr6:111140827-111140907 1.2e-05 59_[+2]_13 chr9:102064158-102064238 1.2e-05 62_[+2]_10 chr4:151959757-151959837 1.2e-05 33_[+2]_39 chr8:101514065-101514145 1.2e-05 60_[+2]_12 chr13:61158225-61158305 1.2e-05 14_[+2]_58 chr2:231519571-231519651 1.2e-05 32_[+2]_40 chr10:3933017-3933097 1.2e-05 31_[+2]_41 chr10:75939017-75939097 1.2e-05 62_[+2]_10 chrX:67682119-67682199 1.2e-05 58_[+2]_14 chr20:9006495-9006575 1.2e-05 27_[+2]_45 chr2:47525076-47525156 1.2e-05 48_[+2]_24 chr15:64085292-64085372 1.2e-05 59_[+2]_13 chrX:2420834-2420914 1.2e-05 61_[+2]_11 chr14:64830111-64830191 1.2e-05 58_[+2]_14 chr8:98774862-98774942 1.2e-05 31_[+2]_41 chr3:127451786-127451866 1.2e-05 41_[+2]_31 chr15:90325491-90325571 1.2e-05 55_[+2]_17 chr6:164758802-164758882 1.2e-05 70_[+2]_2 chr1:247531178-247531258 1.2e-05 57_[+2]_15 chr16:12704973-12705053 1.2e-05 58_[+2]_14 chr1:181143056-181143136 1.2e-05 43_[+2]_29 chr1:18748628-18748708 1.2e-05 72_[+2] chrX:3619590-3619670 1.2e-05 54_[+2]_18 chr7:143067411-143067491 1.2e-05 69_[+2]_3 chr1:223079711-223079791 1.2e-05 24_[+2]_48 chr20:34671186-34671266 1.2e-05 27_[+2]_45 chr6:14077552-14077632 1.2e-05 37_[+2]_35 chr21:30164091-30164171 1.2e-05 12_[+2]_60 chr8:29474732-29474812 1.2e-05 50_[+2]_22 chr9:99183097-99183177 2.1e-05 60_[+2]_12 chr1:212651651-212651731 2.1e-05 32_[+2]_40 chr2:152237302-152237382 2.1e-05 41_[+2]_31 chr17:48526205-48526285 2.1e-05 50_[+2]_22 chr12:121455844-12145592 2.1e-05 29_[+2]_43 chr21:37700055-37700135 2.1e-05 50_[+2]_22 chr2:128685146-128685226 2.1e-05 32_[+2]_40 chr1:55359158-55359238 2.1e-05 39_[+2]_33 chr1:26376538-26376618 2.1e-05 28_[+2]_44 chr14:103017351-10301743 2.1e-05 50_[+2]_22 chr1:204141167-204141247 2.1e-05 32_[+2]_40 chr1:67526725-67526805 2.1e-05 21_[+2]_51 chr11:97844213-97844293 3.3e-05 44_[+2]_28 chr19:52290351-52290431 3.3e-05 47_[+2]_25 chr8:20134427-20134507 3.3e-05 52_[+2]_20 chr12:33099596-33099676 4.2e-05 29_[+2]_43 chr3:125919527-125919607 4.2e-05 50_[+2]_22 chr17:13542252-13542332 6.3e-05 70_[+2]_2 chr17:77007703-77007783 6.3e-05 48_[+2]_24 chr2:39377340-39377420 7.8e-05 48_[+2]_24 chr18:874367-874447 8.5e-05 63_[+2]_9 chr16:1344206-1344286 8.5e-05 17_[+2]_55 chr6:5260889-5260969 0.00011 72_[+2] chr12:76077831-76077911 0.00012 54_[+2]_18 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCCATCTT MEME-2 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF TCCATCTT width=8 seqs=57 chr16:20956257-20956337 ( 66) TCCATCTT 1 chr6:158425136-158425216 ( 72) TCCATCTT 1 chr21:34673092-34673172 ( 42) TCCATCTT 1 chr7:151623177-151623257 ( 58) TCCATCTT 1 chr6:111140827-111140907 ( 60) TCCATCTT 1 chr9:102064158-102064238 ( 63) TCCATCTT 1 chr4:151959757-151959837 ( 34) TCCATCTT 1 chr8:101514065-101514145 ( 61) TCCATCTT 1 chr13:61158225-61158305 ( 15) TCCATCTT 1 chr2:231519571-231519651 ( 33) TCCATCTT 1 chr10:3933017-3933097 ( 32) TCCATCTT 1 chr10:75939017-75939097 ( 63) TCCATCTT 1 chrX:67682119-67682199 ( 59) TCCATCTT 1 chr20:9006495-9006575 ( 28) TCCATCTT 1 chr2:47525076-47525156 ( 49) TCCATCTT 1 chr15:64085292-64085372 ( 60) TCCATCTT 1 chrX:2420834-2420914 ( 62) TCCATCTT 1 chr14:64830111-64830191 ( 59) TCCATCTT 1 chr8:98774862-98774942 ( 32) TCCATCTT 1 chr3:127451786-127451866 ( 42) TCCATCTT 1 chr15:90325491-90325571 ( 56) TCCATCTT 1 chr6:164758802-164758882 ( 71) TCCATCTT 1 chr1:247531178-247531258 ( 58) TCCATCTT 1 chr16:12704973-12705053 ( 59) TCCATCTT 1 chr1:181143056-181143136 ( 44) TCCATCTT 1 chr1:18748628-18748708 ( 73) TCCATCTT 1 chrX:3619590-3619670 ( 55) TCCATCTT 1 chr7:143067411-143067491 ( 70) TCCATCTT 1 chr1:223079711-223079791 ( 25) TCCATCTT 1 chr20:34671186-34671266 ( 28) TCCATCTT 1 chr6:14077552-14077632 ( 38) TCCATCTT 1 chr21:30164091-30164171 ( 13) TCCATCTT 1 chr8:29474732-29474812 ( 51) TCCATCTT 1 chr9:99183097-99183177 ( 61) TCCATTTT 1 chr1:212651651-212651731 ( 33) TCCATTTT 1 chr2:152237302-152237382 ( 42) TCCATTTT 1 chr17:48526205-48526285 ( 51) TCCATTTT 1 chr12:121455844-12145592 ( 30) TCCATTTT 1 chr21:37700055-37700135 ( 51) TCCATTTT 1 chr2:128685146-128685226 ( 33) TCCATTTT 1 chr1:55359158-55359238 ( 40) TCCATTTT 1 chr1:26376538-26376618 ( 29) TCCATTTT 1 chr14:103017351-10301743 ( 51) TCCATTTT 1 chr1:204141167-204141247 ( 33) TCCATTTT 1 chr1:67526725-67526805 ( 22) TCCATTTT 1 chr11:97844213-97844293 ( 45) TCCATGTT 1 chr19:52290351-52290431 ( 48) TCCATGTT 1 chr8:20134427-20134507 ( 53) TCCATGTT 1 chr12:33099596-33099676 ( 30) TCCATATT 1 chr3:125919527-125919607 ( 51) TCCATATT 1 chr17:13542252-13542332 ( 71) ACCATCTT 1 chr17:77007703-77007783 ( 49) ACCATCTT 1 chr2:39377340-39377420 ( 49) GCCATCTT 1 chr18:874367-874447 ( 64) TTCATTTT 1 chr16:1344206-1344286 ( 18) TTCATTTT 1 chr6:5260889-5260969 ( 73) GCCATTTT 1 chr12:76077831-76077911 ( 55) TCCATCTG 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCCATCTT MEME-2 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 8.94323 E= 2.7e-066 -264 -1248 -298 208 -1248 176 -1248 -265 -1248 181 -1248 -1248 219 -1248 -1248 -1248 -1248 -1248 -1248 218 -264 119 -239 26 -1248 -1248 -1248 218 -1248 -1248 -397 216 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCCATCTT MEME-2 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 57 E= 2.7e-066 0.035088 0.000000 0.035088 0.929825 0.000000 0.964912 0.000000 0.035088 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.035088 0.649123 0.052632 0.263158 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.017544 0.982456 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCCATCTT MEME-2 regular expression -------------------------------------------------------------------------------- TCCAT[CT]TT -------------------------------------------------------------------------------- Time 8.60 secs. ******************************************************************************** ******************************************************************************** MOTIF CTCTGGTT MEME-3 width = 8 sites = 43 llr = 421 E-value = 9.4e-038 ******************************************************************************** -------------------------------------------------------------------------------- Motif CTCTGGTT MEME-3 Description -------------------------------------------------------------------------------- Simplified A :::::::: pos.-specific C 9:9:::1: probability G ::1:aa:: matrix T :a:a::9a bits 2.2 * * * 2.0 * * * 1.8 * * * * 1.5 * ***** Relative 1.3 ******** Entropy 1.1 ******** (14.1 bits) 0.9 ******** 0.7 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel CTCTGGTT consensus sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTCTGGTT MEME-3 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr3:99495999-99496079 28 1.45e-05 gatggagttg ctctggtt tgaatgcctt chr6:158176305-158176385 15 1.45e-05 gatggagttg ctctggtt cgcatgcctc chrX:40430920-40431000 60 1.45e-05 gatggagtca ctctggtt caaatgcctc chr16:1344206-1344286 52 1.45e-05 gatggagttg ctctggtt cacacgcctc chrX:109244498-109244578 40 1.45e-05 gatggagtcg ctctggtt ctaacgcctc chr7:84451405-84451485 44 1.45e-05 catggagtca ctctggtt aaaacgcttc chr4:185261027-185261107 45 1.45e-05 gatggagtca ctctggtt ccaatgcctc chr15:58644656-58644736 71 1.45e-05 gatggagtca ctctggtt cc chr4:74962375-74962455 44 1.45e-05 gatggagttg ctctggtt aaaacgtctc chr18:43742147-43742227 32 1.45e-05 gatggagtcg ctctggtt caaacacctc chr16:10419931-10420011 15 1.45e-05 gatggagttg ctctggtt caagtgcctc chr4:154458952-154459032 16 1.45e-05 gatggagttg ctctggtt caaaagcctc chr14:103000327-10300040 31 1.45e-05 gatggagttg ctctggtt cacacaactc chr14:31711905-31711985 22 1.45e-05 gatggagttg ctctggtt cacaggcctc chr3:44482940-44483020 58 1.45e-05 gatggagtca ctctggtt caaacgcctc chr17:46903263-46903343 54 1.45e-05 gatggagtca ctctggtt caaacacctc chr12:131847305-13184738 32 1.45e-05 gatggagtca ctctggtt caaacgtctc chr9:132913305-132913385 13 1.45e-05 gatggcgttg ctctggtt caaacaccct chr16:77773536-77773616 58 1.45e-05 gatggagttg ctctggtt caaacgcctc chr7:75473165-75473245 25 1.45e-05 gatggagtca ctctggtt ctaacgcctc chr9:110438244-110438324 16 1.45e-05 gatggagtca ctctggtt caaacgcctc chr20:39577458-39577538 42 1.45e-05 gatggagttg ctctggtt caaatgcctc chr20:46768464-46768544 29 1.45e-05 gatggagttg ctctggtt caagtgcctc chr7:123633156-123633236 36 1.45e-05 gatggagtca ctctggtt ccaatgcttc chr15:68193159-68193239 51 1.45e-05 gatggagttg ctctggtt ccagtgcttc chr14:93042196-93042276 70 1.45e-05 atgggggtca ctctggtt cag chr17:47154388-47154468 41 1.45e-05 gatggagtcg ctctggtt caaacaactc chrX:15901580-15901660 6 1.45e-05 agttg ctctggtt tgattgcctc chr10:45906821-45906901 33 2.85e-05 gatggagttg ctgtggtt caaacacctc chr9:101614428-101614508 29 2.85e-05 gatggagtta ctgtggtt tgaacacccc chr3:138129227-138129307 13 2.85e-05 gatggagttg ctgtggtt cacatgcctc chr15:29965596-29965676 10 2.85e-05 atggagtcg ctgtggtt caaacacctc chr1:223920408-223920488 25 5.12e-05 gatggagttg ctctagtt cacacgcctc chr12:132090122-13209020 38 5.12e-05 gatggagtca ttctggtt caaatgcctc chr16:15581932-15582012 32 5.12e-05 gatggtgttg ttctggtt caaacgcttc chr8:94886427-94886507 27 5.12e-05 gatggagtca ctctagtt cagatgcctc chr15:45876405-45876485 35 7.00e-05 gatggagttg ctctggct caaatgcctc chr1:10754812-10754892 12 7.00e-05 TTCCCCAAAC CTCTGGCT CCGGGAGGAG chr3:45147733-45147813 66 7.00e-05 CCTGCTGAGG CTCTGGCT TTCTATG chr17:37170404-37170484 13 8.11e-05 tggttttcat ctatggtt ctgaaactgc chr22:29549306-29549386 67 9.27e-05 gatggagtcg ctctgttt ccattg chr2:128685146-128685226 57 1.21e-04 gtctactggg gtctggtt cagaagctca chr11:6271239-6271319 56 1.21e-04 CTACCAGCTA CTCTGGAT AAGAGCTCCA -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTCTGGTT MEME-3 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr3:99495999-99496079 1.4e-05 27_[+3]_45 chr6:158176305-158176385 1.4e-05 14_[+3]_58 chrX:40430920-40431000 1.4e-05 59_[+3]_13 chr16:1344206-1344286 1.4e-05 51_[+3]_21 chrX:109244498-109244578 1.4e-05 39_[+3]_33 chr7:84451405-84451485 1.4e-05 43_[+3]_29 chr4:185261027-185261107 1.4e-05 44_[+3]_28 chr15:58644656-58644736 1.4e-05 70_[+3]_2 chr4:74962375-74962455 1.4e-05 43_[+3]_29 chr18:43742147-43742227 1.4e-05 31_[+3]_41 chr16:10419931-10420011 1.4e-05 14_[+3]_58 chr4:154458952-154459032 1.4e-05 15_[+3]_57 chr14:103000327-10300040 1.4e-05 30_[+3]_42 chr14:31711905-31711985 1.4e-05 21_[+3]_51 chr3:44482940-44483020 1.4e-05 57_[+3]_15 chr17:46903263-46903343 1.4e-05 53_[+3]_19 chr12:131847305-13184738 1.4e-05 31_[+3]_41 chr9:132913305-132913385 1.4e-05 12_[+3]_60 chr16:77773536-77773616 1.4e-05 57_[+3]_15 chr7:75473165-75473245 1.4e-05 24_[+3]_48 chr9:110438244-110438324 1.4e-05 15_[+3]_57 chr20:39577458-39577538 1.4e-05 41_[+3]_31 chr20:46768464-46768544 1.4e-05 28_[+3]_44 chr7:123633156-123633236 1.4e-05 35_[+3]_37 chr15:68193159-68193239 1.4e-05 50_[+3]_22 chr14:93042196-93042276 1.4e-05 69_[+3]_3 chr17:47154388-47154468 1.4e-05 40_[+3]_32 chrX:15901580-15901660 1.4e-05 5_[+3]_67 chr10:45906821-45906901 2.9e-05 32_[+3]_40 chr9:101614428-101614508 2.9e-05 28_[+3]_44 chr3:138129227-138129307 2.9e-05 12_[+3]_60 chr15:29965596-29965676 2.9e-05 9_[+3]_63 chr1:223920408-223920488 5.1e-05 24_[+3]_48 chr12:132090122-13209020 5.1e-05 37_[+3]_35 chr16:15581932-15582012 5.1e-05 31_[+3]_41 chr8:94886427-94886507 5.1e-05 26_[+3]_46 chr15:45876405-45876485 7e-05 34_[+3]_38 chr1:10754812-10754892 7e-05 11_[+3]_61 chr3:45147733-45147813 7e-05 65_[+3]_7 chr17:37170404-37170484 8.1e-05 12_[+3]_60 chr22:29549306-29549386 9.3e-05 66_[+3]_6 chr2:128685146-128685226 0.00012 56_[+3]_16 chr11:6271239-6271319 0.00012 55_[+3]_17 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTCTGGTT MEME-3 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF CTCTGGTT width=8 seqs=43 chr3:99495999-99496079 ( 28) CTCTGGTT 1 chr6:158176305-158176385 ( 15) CTCTGGTT 1 chrX:40430920-40431000 ( 60) CTCTGGTT 1 chr16:1344206-1344286 ( 52) CTCTGGTT 1 chrX:109244498-109244578 ( 40) CTCTGGTT 1 chr7:84451405-84451485 ( 44) CTCTGGTT 1 chr4:185261027-185261107 ( 45) CTCTGGTT 1 chr15:58644656-58644736 ( 71) CTCTGGTT 1 chr4:74962375-74962455 ( 44) CTCTGGTT 1 chr18:43742147-43742227 ( 32) CTCTGGTT 1 chr16:10419931-10420011 ( 15) CTCTGGTT 1 chr4:154458952-154459032 ( 16) CTCTGGTT 1 chr14:103000327-10300040 ( 31) CTCTGGTT 1 chr14:31711905-31711985 ( 22) CTCTGGTT 1 chr3:44482940-44483020 ( 58) CTCTGGTT 1 chr17:46903263-46903343 ( 54) CTCTGGTT 1 chr12:131847305-13184738 ( 32) CTCTGGTT 1 chr9:132913305-132913385 ( 13) CTCTGGTT 1 chr16:77773536-77773616 ( 58) CTCTGGTT 1 chr7:75473165-75473245 ( 25) CTCTGGTT 1 chr9:110438244-110438324 ( 16) CTCTGGTT 1 chr20:39577458-39577538 ( 42) CTCTGGTT 1 chr20:46768464-46768544 ( 29) CTCTGGTT 1 chr7:123633156-123633236 ( 36) CTCTGGTT 1 chr15:68193159-68193239 ( 51) CTCTGGTT 1 chr14:93042196-93042276 ( 70) CTCTGGTT 1 chr17:47154388-47154468 ( 41) CTCTGGTT 1 chrX:15901580-15901660 ( 6) CTCTGGTT 1 chr10:45906821-45906901 ( 33) CTGTGGTT 1 chr9:101614428-101614508 ( 29) CTGTGGTT 1 chr3:138129227-138129307 ( 13) CTGTGGTT 1 chr15:29965596-29965676 ( 10) CTGTGGTT 1 chr1:223920408-223920488 ( 25) CTCTAGTT 1 chr12:132090122-13209020 ( 38) TTCTGGTT 1 chr16:15581932-15582012 ( 32) TTCTGGTT 1 chr8:94886427-94886507 ( 27) CTCTAGTT 1 chr15:45876405-45876485 ( 35) CTCTGGCT 1 chr1:10754812-10754892 ( 12) CTCTGGCT 1 chr3:45147733-45147813 ( 66) CTCTGGCT 1 chr17:37170404-37170484 ( 13) CTATGGTT 1 chr22:29549306-29549386 ( 67) CTCTGTTT 1 chr2:128685146-128685226 ( 57) GTCTGGTT 1 chr11:6271239-6271319 ( 56) CTCTGGAT 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTCTGGTT MEME-3 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 9.05698 E= 9.4e-038 -1207 171 -357 -224 -1207 -1207 -1207 218 -323 163 -157 -1207 -1207 -1207 -1207 218 -223 -1207 179 -1207 -1207 -1207 182 -324 -323 -203 -1207 204 -1207 -1207 -1207 218 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTCTGGTT MEME-3 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 43 E= 9.4e-038 0.000000 0.930233 0.023256 0.046512 0.000000 0.000000 0.000000 1.000000 0.023256 0.883721 0.093023 0.000000 0.000000 0.000000 0.000000 1.000000 0.046512 0.000000 0.953488 0.000000 0.000000 0.000000 0.976744 0.023256 0.023256 0.069767 0.000000 0.906977 0.000000 0.000000 0.000000 1.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTCTGGTT MEME-3 regular expression -------------------------------------------------------------------------------- CTCTGGTT -------------------------------------------------------------------------------- Time 12.24 secs. ******************************************************************************** ******************************************************************************** MOTIF AACCAGAG MEME-4 width = 8 sites = 36 llr = 371 E-value = 2.6e-035 ******************************************************************************** -------------------------------------------------------------------------------- Motif AACCAGAG MEME-4 Description -------------------------------------------------------------------------------- Simplified A aa::a1a: pos.-specific C ::aa:1:: probability G :::::8:a matrix T :::::::: bits 2.2 * * * 2.0 ** * * 1.8 *** * ** 1.5 ***** ** Relative 1.3 ***** ** Entropy 1.1 ******** (14.9 bits) 0.9 ******** 0.7 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel AACCAGAG consensus sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AACCAGAG MEME-4 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr16:20956257-20956337 54 1.42e-05 gaggcattcg aaccagag caactccatc chr6:158425136-158425216 60 1.42e-05 gaggcgtatg aaccagag cgactccatc chr21:34673092-34673172 30 1.42e-05 gaggtgtttg aaccagag cgactccatc chr9:99183097-99183177 49 1.42e-05 gaggcctgtg aaccagag caactccatt chr9:102064158-102064238 51 1.42e-05 gaggcatttg aaccagag ggactccatc chr12:76077831-76077911 43 1.42e-05 gaggcatgtg aaccagag caactccatc chr4:151959757-151959837 22 1.42e-05 gaggcatttg aaccagag cgactccatc chr12:33099596-33099676 18 1.42e-05 gagacatttg aaccagag tgactccata chr3:101362786-101362866 63 1.42e-05 gagctgttag aaccagag tgactccatc chrX:67682119-67682199 47 1.42e-05 gaggcactcg aaccagag tgactccatc chr2:47525076-47525156 37 1.42e-05 gaggcgtttg aaccagag tgactccatc chr15:64085292-64085372 48 1.42e-05 gaggcgtctg aaccagag caactccatc chr14:64830111-64830191 47 1.42e-05 gaggcattag aaccagag caactccatc chr3:127451786-127451866 30 1.42e-05 gaggcgtttg aaccagag caactccatc chr17:77007703-77007783 37 1.42e-05 gaggccttcg aaccagag caacaccatc chr15:90325491-90325571 44 1.42e-05 gaggtgtttg aaccagag cgattccatc chr6:164758802-164758882 59 1.42e-05 gaggtatttg aaccagag cgactccatc chr19:52290351-52290431 36 1.42e-05 gaggcactgg aaccagag caactccatg chr16:12704973-12705053 47 1.42e-05 gagggatttg aaccagag caactccatc chr14:103017351-10301743 39 1.42e-05 gaggcatttg aaccagag caactccatt chr1:181143056-181143136 32 1.42e-05 aaggcgttgg aaccagag tgactccatc chrX:3619590-3619670 43 1.42e-05 gcggcatctg aaccagag caactccatc chr7:143067411-143067491 58 1.42e-05 gaggcaattg aaccagag caactccatc chr1:223079711-223079791 13 1.42e-05 gaggcgtttg aaccagag caactccatc chr20:34671186-34671266 16 1.42e-05 gaggcgtttg aaccagag caactccatc chr8:20134427-20134507 41 1.42e-05 gaggcatttg aaccagag caactccatg chr8:29474732-29474812 39 1.42e-05 gagatgttcg aaccagag caactccatc chr6:111140827-111140907 48 2.89e-05 caggcatttg aaccacag tgactccatc chr7:22219179-22219259 38 2.89e-05 aggcatccta aaccacag ggtgagatag chr2:231519571-231519651 21 2.89e-05 aaggcgtttg aaccacag caactccatc chr7:158611325-158611405 60 2.89e-05 CCAGCCTCAC AACCACAG CACAGAGTCA chr8:98774862-98774942 20 2.89e-05 gaggcgttgg aaccacag tgactccatc chr4:57566970-57567050 72 4.02e-05 gaggcattct aaccaaag t chr17:13542252-13542332 59 4.02e-05 gaggcattca aaccaaag cgacaccatc chr1:18748628-18748708 61 5.12e-05 ggggcgtttg aacaagag tgactccatc chr21:30164091-30164171 1 6.55e-05 . Taccagag tgactccatc -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AACCAGAG MEME-4 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr16:20956257-20956337 1.4e-05 53_[+4]_19 chr6:158425136-158425216 1.4e-05 59_[+4]_13 chr21:34673092-34673172 1.4e-05 29_[+4]_43 chr9:99183097-99183177 1.4e-05 48_[+4]_24 chr9:102064158-102064238 1.4e-05 50_[+4]_22 chr12:76077831-76077911 1.4e-05 42_[+4]_30 chr4:151959757-151959837 1.4e-05 21_[+4]_51 chr12:33099596-33099676 1.4e-05 17_[+4]_55 chr3:101362786-101362866 1.4e-05 62_[+4]_10 chrX:67682119-67682199 1.4e-05 46_[+4]_26 chr2:47525076-47525156 1.4e-05 36_[+4]_36 chr15:64085292-64085372 1.4e-05 47_[+4]_25 chr14:64830111-64830191 1.4e-05 46_[+4]_26 chr3:127451786-127451866 1.4e-05 29_[+4]_43 chr17:77007703-77007783 1.4e-05 36_[+4]_36 chr15:90325491-90325571 1.4e-05 43_[+4]_29 chr6:164758802-164758882 1.4e-05 58_[+4]_14 chr19:52290351-52290431 1.4e-05 35_[+4]_37 chr16:12704973-12705053 1.4e-05 46_[+4]_26 chr14:103017351-10301743 1.4e-05 38_[+4]_34 chr1:181143056-181143136 1.4e-05 31_[+4]_41 chrX:3619590-3619670 1.4e-05 42_[+4]_30 chr7:143067411-143067491 1.4e-05 57_[+4]_15 chr1:223079711-223079791 1.4e-05 12_[+4]_60 chr20:34671186-34671266 1.4e-05 15_[+4]_57 chr8:20134427-20134507 1.4e-05 40_[+4]_32 chr8:29474732-29474812 1.4e-05 38_[+4]_34 chr6:111140827-111140907 2.9e-05 47_[+4]_25 chr7:22219179-22219259 2.9e-05 37_[+4]_35 chr2:231519571-231519651 2.9e-05 20_[+4]_52 chr7:158611325-158611405 2.9e-05 59_[+4]_13 chr8:98774862-98774942 2.9e-05 19_[+4]_53 chr4:57566970-57567050 4e-05 71_[+4]_1 chr17:13542252-13542332 4e-05 58_[+4]_14 chr1:18748628-18748708 5.1e-05 60_[+4]_12 chr21:30164091-30164171 6.5e-05 [+4]_72 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AACCAGAG MEME-4 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF AACCAGAG width=8 seqs=36 chr16:20956257-20956337 ( 54) AACCAGAG 1 chr6:158425136-158425216 ( 60) AACCAGAG 1 chr21:34673092-34673172 ( 30) AACCAGAG 1 chr9:99183097-99183177 ( 49) AACCAGAG 1 chr9:102064158-102064238 ( 51) AACCAGAG 1 chr12:76077831-76077911 ( 43) AACCAGAG 1 chr4:151959757-151959837 ( 22) AACCAGAG 1 chr12:33099596-33099676 ( 18) AACCAGAG 1 chr3:101362786-101362866 ( 63) AACCAGAG 1 chrX:67682119-67682199 ( 47) AACCAGAG 1 chr2:47525076-47525156 ( 37) AACCAGAG 1 chr15:64085292-64085372 ( 48) AACCAGAG 1 chr14:64830111-64830191 ( 47) AACCAGAG 1 chr3:127451786-127451866 ( 30) AACCAGAG 1 chr17:77007703-77007783 ( 37) AACCAGAG 1 chr15:90325491-90325571 ( 44) AACCAGAG 1 chr6:164758802-164758882 ( 59) AACCAGAG 1 chr19:52290351-52290431 ( 36) AACCAGAG 1 chr16:12704973-12705053 ( 47) AACCAGAG 1 chr14:103017351-10301743 ( 39) AACCAGAG 1 chr1:181143056-181143136 ( 32) AACCAGAG 1 chrX:3619590-3619670 ( 43) AACCAGAG 1 chr7:143067411-143067491 ( 58) AACCAGAG 1 chr1:223079711-223079791 ( 13) AACCAGAG 1 chr20:34671186-34671266 ( 16) AACCAGAG 1 chr8:20134427-20134507 ( 41) AACCAGAG 1 chr8:29474732-29474812 ( 39) AACCAGAG 1 chr6:111140827-111140907 ( 48) AACCACAG 1 chr7:22219179-22219259 ( 38) AACCACAG 1 chr2:231519571-231519651 ( 21) AACCACAG 1 chr7:158611325-158611405 ( 60) AACCACAG 1 chr8:98774862-98774942 ( 20) AACCACAG 1 chr4:57566970-57567050 ( 72) AACCAAAG 1 chr17:13542252-13542332 ( 59) AACCAAAG 1 chr1:18748628-18748708 ( 61) AACAAGAG 1 chr21:30164091-30164171 ( 1) TACCAGAG 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AACCAGAG MEME-4 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 9.11739 E= 2.6e-035 215 -1181 -1181 -298 219 -1181 -1181 -1181 -1181 181 -1181 -1181 -297 177 -1181 -1181 219 -1181 -1181 -1181 -197 -104 154 -1181 219 -1181 -1181 -1181 -1181 -1181 186 -1181 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AACCAGAG MEME-4 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 36 E= 2.6e-035 0.972222 0.000000 0.000000 0.027778 1.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.027778 0.972222 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.055556 0.138889 0.805556 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AACCAGAG MEME-4 regular expression -------------------------------------------------------------------------------- AACCAGAG -------------------------------------------------------------------------------- Time 15.81 secs. ******************************************************************************** ******************************************************************************** MOTIF TGTCAGAG MEME-5 width = 8 sites = 40 llr = 386 E-value = 9.0e-031 ******************************************************************************** -------------------------------------------------------------------------------- Motif TGTCAGAG MEME-5 Description -------------------------------------------------------------------------------- Simplified A :1::91a: pos.-specific C :11a1::: probability G :9:::a:a matrix T a:a::::: bits 2.2 2.0 * * 1.8 * *** ** 1.5 * ****** Relative 1.3 ******** Entropy 1.1 ******** (13.9 bits) 0.9 ******** 0.7 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel TGTCAGAG consensus sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGTCAGAG MEME-5 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr16:20956257-20956337 39 1.39e-05 catcccaaac tgtcagag gcattcgaac chr6:158425136-158425216 45 1.39e-05 CACACGCCAT tgtcagag gcgtatgaac chr16:17684907-17684987 62 1.39e-05 AGGTTAGTAC tgtcagag gcatttgaac chr9:99183097-99183177 34 1.39e-05 CAGCCCATAA tgtcagag gcctgtgaac chr9:102064158-102064238 36 1.39e-05 CTACCCCCAC tgtcagag gcatttgaac chr12:76077831-76077911 28 1.39e-05 TATATGACAT tgtcagag gcatgtgaac chr4:151959757-151959837 7 1.39e-05 GCATAT tgtcagag gcatttgaac chr12:96476854-96476934 60 1.39e-05 CAGAGAAGGT tgtcagag gtgtttgaac chr4:57566970-57567050 57 1.39e-05 ctgcttacac tgtcagag gcattctaac chr10:3933017-3933097 5 1.39e-05 GCTT tgtcagag gtgtttgaac chr3:101362786-101362866 48 1.39e-05 ccatcaatga tgtcagag ctgttagaac chrX:67682119-67682199 32 1.39e-05 ttaataataa tgtcagag gcactcgaac chr2:47525076-47525156 22 1.39e-05 TAGTCATAAT tgtcagag gcgtttgaac chr14:64830111-64830191 32 1.39e-05 CAGGAGGTTC tgtcagag gcattagaac chr8:98774862-98774942 5 1.39e-05 ttat tgtcagag gcgttggaac chr19:52290351-52290431 21 1.39e-05 ACTGTAATGA tgtcagag gcactggaac chr16:12704973-12705053 32 1.39e-05 GTCATAATGG tgtcagag ggatttgaac chr14:103017351-10301743 24 1.39e-05 TGATTCTGGC tgtcagag gcatttgaac chr11:86648339-86648419 68 1.39e-05 ATTATAGAAT tgtcagag gcgtc chr7:143067411-143067491 43 1.39e-05 ggggctcccc tgtcagag gcaattgaac chr20:34671186-34671266 1 1.39e-05 . tgtcagag gcgtttgaac chr8:20134427-20134507 26 1.39e-05 AGGGTAAGCA tgtcagag gcatttgaac chr6:14077552-14077632 11 1.39e-05 TATATGGTTG tgtcagag gcattggaac chr10:15669685-15669765 65 1.39e-05 TGCCTCCTAC tgtcagag gcatttga chr8:29474732-29474812 24 1.39e-05 ATGCTGACAT tgtcagag atgttcgaac chr2:231519571-231519651 6 3.60e-05 GAAGC tgtcaaag gcgtttgaac chr10:75939017-75939097 36 3.60e-05 GACATGTTCC tatcagag gcatttgagc chr6:164758802-164758882 44 3.60e-05 TCCCTCTCTG tatcagag gtatttgaac chr1:181143056-181143136 17 3.60e-05 GGCACGTCAT tgtcaaag gcgttggaac chr3:48699257-48699337 10 5.41e-05 CTCGGGAGC TGTCCGAG ACTCGCGGGG chr11:9385613-9385693 28 5.41e-05 GACCCGCGGC TGTCCGAG GCCTCAGTTG chr19:7627865-7627945 42 5.41e-05 GGGATGGTGC TGTCCGAG GTGCTACTGA chr21:34673092-34673172 15 6.84e-05 ctgatgccGT TCtcagag gtgtttgaac chr17:77007703-77007783 22 6.84e-05 CCAGTGGCTC TCtcagag gccttcgaac chr15:64085292-64085372 33 8.65e-05 ctccaggaac tgccagag gcgtctgaac chr3:127451786-127451866 15 8.65e-05 AGGGTGAGAG tgccagag gcgtttgaac chr1:247531178-247531258 31 9.76e-05 tgagtccaga tgtcagat atatttgaac chr3:45209074-45209154 54 1.11e-04 CTGCtgtgtg agtcagag tcaggcagga chr15:90325491-90325571 29 1.47e-04 CAGGTGGCAT Cgtcagag gtgtttgaac chr20:35012574-35012654 20 1.47e-04 TTAGTGCTGA TGTCAGGG GTGTTGTCCG -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGTCAGAG MEME-5 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr16:20956257-20956337 1.4e-05 38_[+5]_34 chr6:158425136-158425216 1.4e-05 44_[+5]_28 chr16:17684907-17684987 1.4e-05 61_[+5]_11 chr9:99183097-99183177 1.4e-05 33_[+5]_39 chr9:102064158-102064238 1.4e-05 35_[+5]_37 chr12:76077831-76077911 1.4e-05 27_[+5]_45 chr4:151959757-151959837 1.4e-05 6_[+5]_66 chr12:96476854-96476934 1.4e-05 59_[+5]_13 chr4:57566970-57567050 1.4e-05 56_[+5]_16 chr10:3933017-3933097 1.4e-05 4_[+5]_68 chr3:101362786-101362866 1.4e-05 47_[+5]_25 chrX:67682119-67682199 1.4e-05 31_[+5]_41 chr2:47525076-47525156 1.4e-05 21_[+5]_51 chr14:64830111-64830191 1.4e-05 31_[+5]_41 chr8:98774862-98774942 1.4e-05 4_[+5]_68 chr19:52290351-52290431 1.4e-05 20_[+5]_52 chr16:12704973-12705053 1.4e-05 31_[+5]_41 chr14:103017351-10301743 1.4e-05 23_[+5]_49 chr11:86648339-86648419 1.4e-05 67_[+5]_5 chr7:143067411-143067491 1.4e-05 42_[+5]_30 chr20:34671186-34671266 1.4e-05 [+5]_72 chr8:20134427-20134507 1.4e-05 25_[+5]_47 chr6:14077552-14077632 1.4e-05 10_[+5]_62 chr10:15669685-15669765 1.4e-05 64_[+5]_8 chr8:29474732-29474812 1.4e-05 23_[+5]_49 chr2:231519571-231519651 3.6e-05 5_[+5]_67 chr10:75939017-75939097 3.6e-05 35_[+5]_37 chr6:164758802-164758882 3.6e-05 43_[+5]_29 chr1:181143056-181143136 3.6e-05 16_[+5]_56 chr3:48699257-48699337 5.4e-05 9_[+5]_63 chr11:9385613-9385693 5.4e-05 27_[+5]_45 chr19:7627865-7627945 5.4e-05 41_[+5]_31 chr21:34673092-34673172 6.8e-05 14_[+5]_58 chr17:77007703-77007783 6.8e-05 21_[+5]_51 chr15:64085292-64085372 8.6e-05 32_[+5]_40 chr3:127451786-127451866 8.6e-05 14_[+5]_58 chr1:247531178-247531258 9.8e-05 30_[+5]_42 chr3:45209074-45209154 0.00011 53_[+5]_19 chr15:90325491-90325571 0.00015 28_[+5]_44 chr20:35012574-35012654 0.00015 19_[+5]_53 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGTCAGAG MEME-5 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF TGTCAGAG width=8 seqs=40 chr16:20956257-20956337 ( 39) TGTCAGAG 1 chr6:158425136-158425216 ( 45) TGTCAGAG 1 chr16:17684907-17684987 ( 62) TGTCAGAG 1 chr9:99183097-99183177 ( 34) TGTCAGAG 1 chr9:102064158-102064238 ( 36) TGTCAGAG 1 chr12:76077831-76077911 ( 28) TGTCAGAG 1 chr4:151959757-151959837 ( 7) TGTCAGAG 1 chr12:96476854-96476934 ( 60) TGTCAGAG 1 chr4:57566970-57567050 ( 57) TGTCAGAG 1 chr10:3933017-3933097 ( 5) TGTCAGAG 1 chr3:101362786-101362866 ( 48) TGTCAGAG 1 chrX:67682119-67682199 ( 32) TGTCAGAG 1 chr2:47525076-47525156 ( 22) TGTCAGAG 1 chr14:64830111-64830191 ( 32) TGTCAGAG 1 chr8:98774862-98774942 ( 5) TGTCAGAG 1 chr19:52290351-52290431 ( 21) TGTCAGAG 1 chr16:12704973-12705053 ( 32) TGTCAGAG 1 chr14:103017351-10301743 ( 24) TGTCAGAG 1 chr11:86648339-86648419 ( 68) TGTCAGAG 1 chr7:143067411-143067491 ( 43) TGTCAGAG 1 chr20:34671186-34671266 ( 1) TGTCAGAG 1 chr8:20134427-20134507 ( 26) TGTCAGAG 1 chr6:14077552-14077632 ( 11) TGTCAGAG 1 chr10:15669685-15669765 ( 65) TGTCAGAG 1 chr8:29474732-29474812 ( 24) TGTCAGAG 1 chr2:231519571-231519651 ( 6) TGTCAAAG 1 chr10:75939017-75939097 ( 36) TATCAGAG 1 chr6:164758802-164758882 ( 44) TATCAGAG 1 chr1:181143056-181143136 ( 17) TGTCAAAG 1 chr3:48699257-48699337 ( 10) TGTCCGAG 1 chr11:9385613-9385693 ( 28) TGTCCGAG 1 chr19:7627865-7627945 ( 42) TGTCCGAG 1 chr21:34673092-34673172 ( 15) TCTCAGAG 1 chr17:77007703-77007783 ( 22) TCTCAGAG 1 chr15:64085292-64085372 ( 33) TGCCAGAG 1 chr3:127451786-127451866 ( 15) TGCCAGAG 1 chr1:247531178-247531258 ( 31) TGTCAGAT 1 chr3:45209074-45209154 ( 54) AGTCAGAG 1 chr15:90325491-90325571 ( 29) CGTCAGAG 1 chr20:35012574-35012654 ( 20) TGTCAGGG 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGTCAGAG MEME-5 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 9.77545 E= 9.0e-031 -312 -351 -1197 211 -213 -251 170 -1197 -1197 -251 -1197 211 -1197 181 -1197 -1197 208 -193 -1197 -1197 -213 -1197 178 -1197 216 -1197 -346 -1197 -1197 -1197 182 -313 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGTCAGAG MEME-5 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 40 E= 9.0e-031 0.025000 0.025000 0.000000 0.950000 0.050000 0.050000 0.900000 0.000000 0.000000 0.050000 0.000000 0.950000 0.000000 1.000000 0.000000 0.000000 0.925000 0.075000 0.000000 0.000000 0.050000 0.000000 0.950000 0.000000 0.975000 0.000000 0.025000 0.000000 0.000000 0.000000 0.975000 0.025000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGTCAGAG MEME-5 regular expression -------------------------------------------------------------------------------- TGTCAGAG -------------------------------------------------------------------------------- Time 19.23 secs. ******************************************************************************** ******************************************************************************** SUMMARY OF MOTIFS ******************************************************************************** -------------------------------------------------------------------------------- Combined block diagrams: non-overlapping sites with p-value < 0.0001 -------------------------------------------------------------------------------- SEQUENCE NAME COMBINED P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr6:69345075-69345155 9.99e-01 80 chr6:5260889-5260969 1.01e-01 80 chr15:60314163-60314243 4.31e-02 5_[+1(4.67e-05)]_67 chr3:14687937-14688017 5.43e-01 80 chr12:110841414-11084149 6.11e-01 80 chr19:35759269-35759349 8.59e-01 80 chr7:150756604-150756684 1.00e+00 80 chr17:44344179-44344259 9.51e-01 80 chr2:10091602-10091682 1.00e+00 80 chr19:11071624-11071704 8.36e-01 80 chr1:67526725-67526805 7.42e-03 21_[+2(2.10e-05)]_51 chr1:40367567-40367647 9.96e-01 80 chr11:221059-221139 6.92e-01 80 chr11:13299075-13299155 7.77e-01 80 chr1:204141167-204141247 1.17e-02 32_[+2(2.10e-05)]_40 chrX:15901580-15901660 6.05e-02 5_[+3(1.45e-05)]_67 chr17:47154388-47154468 2.94e-04 28_[+1(1.06e-05)]_4_[+3(1.45e-05)]_\ 32 chr11:71781039-71781119 4.19e-02 80 chr11:6271239-6271319 2.45e-02 80 chr16:1662262-1662342 9.93e-01 80 chr1:9884162-9884242 8.04e-01 80 chr8:29474732-29474812 2.05e-07 23_[+5(1.39e-05)]_7_[+4(1.42e-05)]_\ 4_[+2(1.19e-05)]_22 chr11:35358780-35358860 5.79e-01 80 chr7:130790749-130790829 1.00e+00 80 chr21:30164091-30164171 2.18e-05 [+4(6.55e-05)]_4_[+2(1.19e-05)]_60 chr17:40466092-40466172 1.71e-01 80 chr3:45147733-45147813 1.04e-01 65_[+3(7.00e-05)]_7 chr10:15669685-15669765 1.54e-02 64_[+5(1.39e-05)]_8 chr17:65989832-65989912 9.97e-01 80 chr17:47592699-47592779 2.89e-01 80 chr14:93042196-93042276 1.98e-03 69_[+3(1.45e-05)]_3 chr15:29965596-29965676 3.54e-02 9_[+3(2.85e-05)]_63 chr18:20048273-20048353 3.64e-01 80 chr19:48901984-48902064 9.47e-01 80 chr6:14077552-14077632 3.92e-06 10_[+5(1.39e-05)]_19_[+2(1.19e-05)]_\ 35 chr19:7627865-7627945 1.31e-02 41_[+5(5.41e-05)]_31 chr15:68193159-68193239 1.89e-04 38_[+1(1.06e-05)]_4_[+3(1.45e-05)]_\ 22 chr8:20134427-20134507 2.74e-06 25_[+5(1.39e-05)]_7_[+4(1.42e-05)]_\ 4_[+2(3.25e-05)]_20 chr8:38854429-38854509 1.00e+00 80 chr6:37394925-37395005 2.15e-02 80 chr1:59762442-59762522 9.84e-01 80 chr3:194898960-194899040 8.18e-01 80 chr15:98536650-98536730 2.24e-01 80 chr4:54930854-54930934 9.92e-01 80 chr10:4868271-4868351 7.65e-01 80 chr8:74659085-74659165 9.20e-01 80 chr7:123633156-123633236 5.00e-05 23_[+1(1.06e-05)]_4_[+3(1.45e-05)]_\ 37 chr20:34671186-34671266 1.16e-06 [+5(1.39e-05)]_7_[+4(1.42e-05)]_4_\ [+2(1.19e-05)]_45 chr16:58467699-58467779 8.17e-01 80 chr1:223079711-223079791 2.84e-05 12_[+4(1.42e-05)]_4_[+2(1.19e-05)]_\ 48 chr1:21113795-21113875 9.86e-01 80 chr8:145560353-145560433 9.78e-01 80 chr3:14688138-14688218 4.09e-01 80 chr7:116593765-116593845 9.93e-01 80 chr20:46768464-46768544 1.92e-05 16_[+1(1.06e-05)]_4_[+3(1.45e-05)]_\ 44 chr8:94886427-94886507 7.50e-04 14_[+1(1.06e-05)]_4_[+3(5.12e-05)]_\ 46 chr6:147770850-147770930 2.60e-02 67_[+1(1.06e-05)]_5 chr4:1242465-1242545 9.99e-01 80 chr3:170075147-170075227 9.67e-01 80 chr7:143067411-143067491 3.17e-06 42_[+5(1.39e-05)]_7_[+4(1.42e-05)]_\ 4_[+2(1.19e-05)]_3 chr20:39577458-39577538 7.87e-05 29_[+1(1.06e-05)]_4_[+3(1.45e-05)]_\ 31 chrX:3619590-3619670 3.36e-05 42_[+4(1.42e-05)]_4_[+2(1.19e-05)]_\ 18 chr12:31771236-31771316 6.79e-03 21_[+1(1.91e-05)]_51 chr9:114987090-114987170 6.38e-01 80 chr9:110438244-110438324 8.46e-05 3_[+1(1.06e-05)]_4_[+3(1.45e-05)]_\ 57 chr21:46238028-46238108 9.16e-01 80 chr11:86648339-86648419 3.47e-04 67_[+5(1.39e-05)]_5 chr2:10418613-10418693 1.80e-01 80 chr7:75473165-75473245 1.25e-03 12_[+1(1.06e-05)]_4_[+3(1.45e-05)]_\ 48 chr2:68385026-68385106 1.24e-01 80 chr2:205219421-205219501 2.41e-02 10_[+1(1.06e-05)]_62 chr1:18748628-18748708 1.98e-05 60_[+4(5.12e-05)]_4_[+2(1.19e-05)] chr1:181143056-181143136 1.72e-06 16_[+5(3.60e-05)]_7_[+4(1.42e-05)]_\ 4_[+2(1.19e-05)]_29 chr14:103017351-10301743 6.26e-08 23_[+5(1.39e-05)]_7_[+4(1.42e-05)]_\ 4_[+2(2.10e-05)]_22 chr10:27530655-27530735 4.85e-01 80 chr11:78128954-78129034 9.99e-01 80 chr19:4400577-4400657 9.24e-01 80 chr20:35012574-35012654 5.67e-03 45_[+1(2.75e-05)]_27 chr16:12704973-12705053 3.72e-07 31_[+5(1.39e-05)]_7_[+4(1.42e-05)]_\ 4_[+2(1.19e-05)]_14 chr8:142402137-142402217 9.62e-01 80 chr7:73867195-73867275 2.98e-02 24_[+1(1.06e-05)]_48 chr1:247531178-247531258 9.81e-07 30_[+5(9.76e-05)]_7_[+4(5.12e-05)]_\ 4_[+2(1.19e-05)]_15 chr19:52290351-52290431 8.75e-06 20_[+5(1.39e-05)]_7_[+4(1.42e-05)]_\ 4_[+2(3.25e-05)]_25 chr1:10754812-10754892 1.84e-01 11_[+3(7.00e-05)]_61 chr6:164758802-164758882 6.14e-07 43_[+5(3.60e-05)]_7_[+4(1.42e-05)]_\ 4_[+2(1.19e-05)]_2 chr3:125919527-125919607 9.15e-02 50_[+2(4.17e-05)]_22 chr6:167368756-167368836 9.96e-01 80 chr16:77773536-77773616 7.31e-04 45_[+1(1.06e-05)]_4_[+3(1.45e-05)]_\ 15 chr19:4342876-4342956 1.36e-01 80 chr6:7167204-7167284 5.26e-01 80 chr15:90325491-90325571 6.98e-06 43_[+4(1.42e-05)]_4_[+2(1.19e-05)]_\ 17 chr9:132913305-132913385 1.66e-03 [+1(6.05e-05)]_4_[+3(1.45e-05)]_60 chr11:925759-925839 9.97e-01 80 chr11:9385613-9385693 1.16e-01 27_[+5(5.41e-05)]_45 chr9:126872743-126872823 9.55e-01 80 chr1:26376538-26376618 2.67e-02 28_[+2(2.10e-05)]_44 chr17:77007703-77007783 2.07e-05 21_[+5(6.84e-05)]_7_[+4(1.42e-05)]_\ 4_[+2(6.27e-05)]_24 chr1:55359158-55359238 5.02e-04 39_[+2(2.10e-05)]_33 chr16:15581932-15582012 2.14e-03 19_[+1(4.67e-05)]_4_[+3(5.12e-05)]_\ 41 chr1:110522352-110522432 9.13e-01 80 chr8:10847824-10847904 5.67e-03 80 chr1:222135848-222135928 6.81e-02 39_[+1(8.23e-05)]_33 chr2:128685146-128685226 2.27e-03 32_[+2(2.10e-05)]_40 chr3:127451786-127451866 2.98e-06 14_[+5(8.65e-05)]_7_[+4(1.42e-05)]_\ 4_[+2(1.19e-05)]_31 chr21:37700055-37700135 1.47e-02 50_[+2(2.10e-05)]_22 chr8:98774862-98774942 1.18e-06 4_[+5(1.39e-05)]_7_[+4(2.89e-05)]_4_\ [+2(1.19e-05)]_41 chr6:12023328-12023408 1.21e-02 13_[+1(6.05e-05)]_59 chr17:13542252-13542332 4.18e-04 58_[+4(4.02e-05)]_4_[+2(6.27e-05)]_\ 2 chr14:64830111-64830191 7.78e-07 31_[+5(1.39e-05)]_7_[+4(1.42e-05)]_\ 4_[+2(1.19e-05)]_14 chr19:50082618-50082698 7.93e-03 [+1(1.91e-05)]_72 chr3:138129227-138129307 8.28e-04 [+1(1.06e-05)]_4_[+3(2.85e-05)]_60 chr2:102875175-102875255 4.90e-01 80 chr12:131847305-13184738 5.67e-05 19_[+1(1.06e-05)]_4_[+3(1.45e-05)]_\ 41 chr12:121455844-12145592 2.69e-02 29_[+2(2.10e-05)]_43 chr17:46903263-46903343 1.70e-04 41_[+1(1.06e-05)]_4_[+3(1.45e-05)]_\ 19 chr4:79615503-79615583 2.43e-02 29_[+1(1.06e-05)]_43 chr4:38939086-38939166 5.78e-01 80 chr1:31956197-31956277 1.06e-01 80 chrX:2420834-2420914 3.13e-03 43_[+2(9.38e-05)]_10_[+2(1.19e-05)]_\ 11 chr8:111907144-111907224 4.87e-02 80 chr12:6717075-6717155 7.97e-01 80 chr15:64085292-64085372 7.19e-06 32_[+5(8.65e-05)]_7_[+4(1.42e-05)]_\ 4_[+2(1.19e-05)]_13 chr3:44482940-44483020 1.60e-04 45_[+1(1.06e-05)]_4_[+3(1.45e-05)]_\ 15 chr9:101614428-101614508 4.91e-04 16_[+1(1.06e-05)]_4_[+3(2.85e-05)]_\ 44 chr7:106437322-106437402 7.97e-03 36_[+1(1.06e-05)]_36 chr12:132090122-13209020 6.88e-04 25_[+1(1.06e-05)]_4_[+3(5.12e-05)]_\ 35 chr5:169514587-169514667 8.74e-02 80 chr3:156338148-156338228 5.10e-01 80 chr1:1545339-1545419 1.91e-02 25_[+1(1.91e-05)]_21_[+1(1.91e-05)]_\ 18 chr2:47525076-47525156 3.88e-07 21_[+5(1.39e-05)]_7_[+4(1.42e-05)]_\ 4_[+2(1.19e-05)]_24 chr1:235116801-235116881 4.22e-01 80 chr7:158611325-158611405 3.90e-02 59_[+4(2.89e-05)]_13 chr20:9006495-9006575 2.17e-02 27_[+2(1.19e-05)]_45 chrX:67682119-67682199 3.09e-06 31_[+5(1.39e-05)]_7_[+4(1.42e-05)]_\ 4_[+2(1.19e-05)]_14 chr16:2264916-2264996 8.20e-01 80 chr7:127877307-127877387 9.66e-02 80 chr15:45876405-45876485 6.61e-04 22_[+1(1.06e-05)]_4_[+3(7.00e-05)]_\ 38 chr14:31711905-31711985 4.27e-04 9_[+1(1.06e-05)]_4_[+3(1.45e-05)]_\ 51 chr17:3907951-3908031 1.68e-02 80 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3.24e-04 2_[+1(1.06e-05)]_4_[+3(1.45e-05)]_\ 58 chr2:201991179-201991259 4.53e-03 15_[+1(1.06e-05)]_57 chr3:45209074-45209154 3.42e-02 80 chr17:73179156-73179236 9.67e-01 80 chr3:193308478-193308558 7.20e-04 29_[+1(1.06e-05)]_43 chr18:874367-874447 9.86e-02 63_[+2(8.46e-05)]_9 chr1:234745953-234746033 1.00e+00 80 chr18:5296238-5296318 5.47e-01 80 chr16:20956257-20956337 1.76e-06 38_[+5(1.39e-05)]_7_[+4(1.42e-05)]_\ 4_[+2(1.19e-05)]_7 chr8:41676492-41676572 1.48e-02 16_[+1(3.60e-05)]_56 chr3:99495999-99496079 3.10e-04 15_[+1(1.06e-05)]_4_[+3(1.45e-05)]_\ 45 chr10:21368132-21368212 3.48e-01 80 chr20:49955690-49955770 6.62e-01 80 chr11:44552511-44552591 2.17e-01 80 chr7:30711617-30711697 2.40e-01 80 -------------------------------------------------------------------------------- ******************************************************************************** ******************************************************************************** Stopped because requested number of motifs (5) found. ******************************************************************************** CPU: c22n06.farnam.hpc.yale.internal ********************************************************************************