******************************************************************************** MEME - Motif discovery tool ******************************************************************************** MEME version 5.3.3 (Release date: Sun Feb 7 15:39:52 2021 -0800) For further information on how to interpret these results please access https://meme-suite.org/meme. To get a copy of the MEME Suite software please access https://meme-suite.org. ******************************************************************************** ******************************************************************************** REFERENCE ******************************************************************************** If you use this program in your research, please cite: Timothy L. Bailey and Charles Elkan, "Fitting a mixture model by expectation maximization to discover motifs in biopolymers", Proceedings of the Second International Conference on Intelligent Systems for Molecular Biology, pp. 28-36, AAAI Press, Menlo Park, California, 1994. ******************************************************************************** ******************************************************************************** TRAINING SET ******************************************************************************** PRIMARY SEQUENCES= ../result/final_prediction/K562/fasta/RankLinear0.6_40/ZNF282.fasta CONTROL SEQUENCES= --none-- ALPHABET= ACGT Sequence name Weight Length Sequence name Weight Length ------------- ------ ------ ------------- ------ ------ chr1:98386703-98386783 1.0000 80 chr19:55658433-55658513 1.0000 80 chr10:103880462-10388054 1.0000 80 chr17:1388318-1388398 1.0000 80 chr1:65210301-65210381 1.0000 80 chr14:24439169-24439249 1.0000 80 chr11:129940529-12994060 1.0000 80 chr2:112123948-112124028 1.0000 80 chr4:187645808-187645888 1.0000 80 chr8:81083858-81083938 1.0000 80 chr22:43582852-43582932 1.0000 80 chr20:62370732-62370812 1.0000 80 chr1:9884537-9884617 1.0000 80 chr12:12503091-12503171 1.0000 80 chr1:156647271-156647351 1.0000 80 chr20:57582146-57582226 1.0000 80 chr20:52210162-52210242 1.0000 80 chr2:73297718-73297798 1.0000 80 chr17:55945650-55945730 1.0000 80 chr1:230281953-230282033 1.0000 80 chr15:82339058-82339138 1.0000 80 chr8:96080066-96080146 1.0000 80 chr19:7991489-7991569 1.0000 80 chr19:51326744-51326824 1.0000 80 chr12:65063434-65063514 1.0000 80 chr12:25404331-25404411 1.0000 80 chr1:52456273-52456353 1.0000 80 chr10:103880679-10388075 1.0000 80 chr20:31170986-31171066 1.0000 80 chr22:39410129-39410209 1.0000 80 chr5:137577870-137577950 1.0000 80 chr17:60770467-60770547 1.0000 80 chr3:57004528-57004608 1.0000 80 chr8:15398185-15398265 1.0000 80 chr19:15751529-15751609 1.0000 80 chr14:100011529-10001160 1.0000 80 chr17:40761172-40761252 1.0000 80 chr3:195181230-195181310 1.0000 80 chr7:128050373-128050453 1.0000 80 chr4:85503957-85504037 1.0000 80 chr1:150947409-150947489 1.0000 80 chr5:415657-415737 1.0000 80 chr21:46862753-46862833 1.0000 80 chr14:50863636-50863716 1.0000 80 chr4:185517915-185517995 1.0000 80 chr3:183354581-183354661 1.0000 80 chr10:88281945-88282025 1.0000 80 chr1:956504-956584 1.0000 80 chr17:42296713-42296793 1.0000 80 chrX:46771626-46771706 1.0000 80 chr18:28681402-28681482 1.0000 80 chr17:48238901-48238981 1.0000 80 chr22:39378246-39378326 1.0000 80 chr10:35053700-35053780 1.0000 80 chr17:38477488-38477568 1.0000 80 chr17:79386717-79386797 1.0000 80 chr1:100905811-100905891 1.0000 80 chr9:137217753-137217833 1.0000 80 chr2:87883897-87883977 1.0000 80 chr16:1349539-1349619 1.0000 80 chr12:25404536-25404616 1.0000 80 chr17:21118010-21118090 1.0000 80 chr8:144100466-144100546 1.0000 80 chr10:72994911-72994991 1.0000 80 chr10:71074970-71075050 1.0000 80 chr9:107526389-107526469 1.0000 80 chr19:4679122-4679202 1.0000 80 chr11:65405646-65405726 1.0000 80 chr4:153945304-153945384 1.0000 80 chr10:71892472-71892552 1.0000 80 chr7:95238154-95238234 1.0000 80 chr10:3088168-3088248 1.0000 80 chr21:46274380-46274460 1.0000 80 chr2:74198168-74198248 1.0000 80 chr13:49550374-49550454 1.0000 80 chr17:39705232-39705312 1.0000 80 chr2:68870610-68870690 1.0000 80 chr4:1795183-1795263 1.0000 80 chr7:30810795-30810875 1.0000 80 chr7:158656077-158656157 1.0000 80 chr16:838694-838774 1.0000 80 chrX:24043936-24044016 1.0000 80 chr7:154982502-154982582 1.0000 80 chr12:29301902-29301982 1.0000 80 chr18:72921267-72921347 1.0000 80 chr19:40005727-40005807 1.0000 80 chr4:85504180-85504260 1.0000 80 chr11:67141024-67141104 1.0000 80 chr1:22668726-22668806 1.0000 80 chr1:1136927-1137007 1.0000 80 chr9:107509946-107510026 1.0000 80 chr22:19706615-19706695 1.0000 80 chr2:152117932-152118012 1.0000 80 chr12:6977067-6977147 1.0000 80 chr8:48651494-48651574 1.0000 80 chr2:172958001-172958081 1.0000 80 chr5:139048087-139048167 1.0000 80 chr2:201374643-201374723 1.0000 80 chr17:29035850-29035930 1.0000 80 chr13:30881702-30881782 1.0000 80 chr11:64052680-64052760 1.0000 80 chr17:80255889-80255969 1.0000 80 chr19:17727728-17727808 1.0000 80 chr10:49515131-49515211 1.0000 80 chr11:63974100-63974180 1.0000 80 chr11:46403548-46403628 1.0000 80 chr1:2475795-2475875 1.0000 80 chr17:43242839-43242919 1.0000 80 chr10:88281740-88281820 1.0000 80 chr8:142427874-142427954 1.0000 80 chr1:6266154-6266234 1.0000 80 chrX:13707392-13707472 1.0000 80 chr3:182972012-182972092 1.0000 80 chr19:11689147-11689227 1.0000 80 chr10:92863612-92863692 1.0000 80 chr5:150143098-150143178 1.0000 80 chr19:42817510-42817590 1.0000 80 chr1:107600048-107600128 1.0000 80 chr19:9903649-9903729 1.0000 80 chr1:3458707-3458787 1.0000 80 chr12:53268238-53268318 1.0000 80 chr12:49659317-49659397 1.0000 80 chr17:74237041-74237121 1.0000 80 chr4:129733107-129733187 1.0000 80 chr3:14167373-14167453 1.0000 80 chr11:118977771-11897785 1.0000 80 chr2:73297921-73298001 1.0000 80 chr8:145987897-145987977 1.0000 80 chr9:127615481-127615561 1.0000 80 chr3:193858705-193858785 1.0000 80 chr1:23730476-23730556 1.0000 80 chr1:33207148-33207228 1.0000 80 chr7:1501163-1501243 1.0000 80 chr19:44123956-44124036 1.0000 80 chr7:47514956-47515036 1.0000 80 chr17:3867759-3867839 1.0000 80 chr19:38747272-38747352 1.0000 80 chr3:9975034-9975114 1.0000 80 chr6:32122290-32122370 1.0000 80 chr10:6622466-6622546 1.0000 80 chr6:20404137-20404217 1.0000 80 chr19:9896629-9896709 1.0000 80 chrX:47796097-47796177 1.0000 80 chr18:72921569-72921649 1.0000 80 chr12:122064166-12206424 1.0000 80 chr2:27243579-27243659 1.0000 80 chr3:160473019-160473099 1.0000 80 chr6:106494469-106494549 1.0000 80 chrX:153719222-153719302 1.0000 80 chr1:249167521-249167601 1.0000 80 chr19:19643372-19643452 1.0000 80 chr16:88527816-88527896 1.0000 80 chr3:187461699-187461779 1.0000 80 chr12:7592884-7592964 1.0000 80 chr19:59055532-59055612 1.0000 80 chr5:56247362-56247442 1.0000 80 chr12:93965895-93965975 1.0000 80 chr19:3036395-3036475 1.0000 80 chr7:25019448-25019528 1.0000 80 chrX:71238400-71238480 1.0000 80 chr10:112631376-11263145 1.0000 80 chr7:64465136-64465216 1.0000 80 chr16:3070075-3070155 1.0000 80 chr1:54955095-54955175 1.0000 80 chr10:98592456-98592536 1.0000 80 chr19:15291913-15291993 1.0000 80 chr5:176882393-176882473 1.0000 80 chr9:101002930-101003010 1.0000 80 chr16:88298666-88298746 1.0000 80 chr22:29593212-29593292 1.0000 80 chr1:95582914-95582994 1.0000 80 chr1:184942839-184942919 1.0000 80 chr19:54372739-54372819 1.0000 80 chr7:128431608-128431688 1.0000 80 chr16:1381760-1381840 1.0000 80 chr21:45139345-45139425 1.0000 80 chr1:45075930-45076010 1.0000 80 chr5:176449689-176449769 1.0000 80 chr6:44187300-44187380 1.0000 80 chr11:66671675-66671755 1.0000 80 chr20:31063417-31063497 1.0000 80 chr1:45262617-45262697 1.0000 80 chr19:39801388-39801468 1.0000 80 chr15:77712251-77712331 1.0000 80 chr18:77267150-77267230 1.0000 80 chr10:71075171-71075251 1.0000 80 chr9:140500501-140500581 1.0000 80 chr11:18548152-18548232 1.0000 80 chr16:29823812-29823892 1.0000 80 chr8:142426083-142426163 1.0000 80 chr9:139581686-139581766 1.0000 80 chr12:49351282-49351362 1.0000 80 chr16:69165947-69166027 1.0000 80 chr9:126116551-126116631 1.0000 80 chr11:65405856-65405936 1.0000 80 chr2:27243368-27243448 1.0000 80 chr19:45417934-45418014 1.0000 80 chr17:1733170-1733250 1.0000 80 chr17:4843542-4843622 1.0000 80 chr9:95946563-95946643 1.0000 80 chr17:53046013-53046093 1.0000 80 chr11:33061274-33061354 1.0000 80 chr8:143696003-143696083 1.0000 80 chr4:5053211-5053291 1.0000 80 chr17:45955143-45955223 1.0000 80 chr2:62732984-62733064 1.0000 80 chr3:49131510-49131590 1.0000 80 chr22:50608593-50608673 1.0000 80 chr3:184053751-184053831 1.0000 80 chr6:34425413-34425493 1.0000 80 chr12:112856950-11285703 1.0000 80 chr11:65308297-65308377 1.0000 80 chr10:31607270-31607350 1.0000 80 chr4:74965145-74965225 1.0000 80 chr8:24858324-24858404 1.0000 80 chr11:13484810-13484890 1.0000 80 chr1:228528803-228528883 1.0000 80 chr7:128471555-128471635 1.0000 80 chr17:40571881-40571961 1.0000 80 chr2:152118141-152118221 1.0000 80 chr17:60781382-60781462 1.0000 80 chr1:151430813-151430893 1.0000 80 chr8:12611689-12611769 1.0000 80 chr19:45748765-45748845 1.0000 80 chr19:18402783-18402863 1.0000 80 chr6:27218919-27218999 1.0000 80 chr15:78730411-78730491 1.0000 80 chr1:145827027-145827107 1.0000 80 chr1:7844151-7844231 1.0000 80 chr7:75368768-75368848 1.0000 80 chr17:14204047-14204127 1.0000 80 chr19:49118086-49118166 1.0000 80 chr19:41196452-41196532 1.0000 80 chr2:202316455-202316535 1.0000 80 chr5:134370266-134370346 1.0000 80 chr9:140512977-140513057 1.0000 80 chr22:38663296-38663376 1.0000 80 chr7:8301655-8301735 1.0000 80 chr4:38665843-38665923 1.0000 80 chrX:39548080-39548160 1.0000 80 chr6:17706597-17706677 1.0000 80 chr19:18549632-18549712 1.0000 80 chr19:10828723-10828803 1.0000 80 chr5:102898220-102898300 1.0000 80 chr10:74036574-74036654 1.0000 80 chr17:37823866-37823946 1.0000 80 chr2:27229633-27229713 1.0000 80 chr12:32832427-32832507 1.0000 80 chr1:173991671-173991751 1.0000 80 chr1:894805-894885 1.0000 80 ******************************************************************************** ******************************************************************************** COMMAND LINE SUMMARY ******************************************************************************** This information can also be useful in the event you wish to report a problem with the MEME software. command: meme -oc ../result/final_prediction/K562/inference_raw/MEME/RankLinear0.6_40_ZNF282/ -dna -nmotifs 5 -w 8 -maxsize 250000 -nostatus ../result/final_prediction/K562/fasta/RankLinear0.6_40/ZNF282.fasta model: mod= zoops nmotifs= 5 evt= inf objective function: em= E-value of product of p-values starts= E-value of product of p-values strands: + width: minw= 8 maxw= 8 nsites: minsites= 2 maxsites= 250 wnsites= 0.8 theta: spmap= uni spfuzz= 0.5 em: prior= dirichlet b= 0.01 maxiter= 50 distance= 1e-05 trim: wg= 11 ws= 1 endgaps= yes data: n= 20000 N= 250 sample: seed= 0 hsfrac= 0 searchsize= 20000 norand= no csites= 1000 Letter frequencies in dataset: A 0.162 C 0.342 G 0.333 T 0.163 Background letter frequencies (from file dataset with add-one prior applied): A 0.162 C 0.342 G 0.333 T 0.163 Background model order: 0 ******************************************************************************** ******************************************************************************** MOTIF TCCCGCMC MEME-1 width = 8 sites = 75 llr = 553 E-value = 2.8e-015 ******************************************************************************** -------------------------------------------------------------------------------- Motif TCCCGCMC MEME-1 Description -------------------------------------------------------------------------------- Simplified A ::::3:4: pos.-specific C :9a9:a2a probability G ::::7:2: matrix T a1:11:2: bits 2.6 * 2.4 * 2.1 * 1.8 * Relative 1.6 * * * * Entropy 1.3 * * * * (10.6 bits) 1.0 **** * * 0.8 ****** * 0.5 ****** * 0.3 ******** 0.0 -------- Multilevel TCCCGCAC consensus A C sequence T -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCCCGCMC MEME-1 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr1:173991671-173991751 58 4.11e-05 CGGTCTGCCC TCCCGCAC CGGCGCCTTT chr8:24858324-24858404 52 4.11e-05 TCTTCCCAGC TCCCGCAC CCCCAGGGCT chr2:62732984-62733064 53 4.11e-05 CAAGGCGCTC TCCCGCAC TGCGGAGAAC chr16:69165947-69166027 33 4.11e-05 AAGAGCCCCT TCCCGCAC GTACCTCGAG chr16:1381760-1381840 41 4.11e-05 CCAAGGGTGC TCCCGCAC CCAACGGACT chr5:176882393-176882473 40 4.11e-05 caccacgcgc tcccgcac ccgccgccta chr12:93965895-93965975 47 4.11e-05 ATGCGGCAGC TCCCGCAC CTCCGCACCC chr8:145987897-145987977 10 4.11e-05 CACTTCACA TCCCGCAC TGAGACGCAC chr12:49659317-49659397 58 4.11e-05 CCTCGTGCGC TCCCGCAC CGACGGTGCA chr1:22668726-22668806 20 4.11e-05 AATCAGGGCC TCCCGCAC CCGCAGCTGG chr17:21118010-21118090 17 4.11e-05 CGGGCGCTGC TCCCGCAC CATCCTCCCC chr12:12503091-12503171 49 4.11e-05 GCTCCGCAGC TCCCGCAC CGGCCTGGCG chr22:38663296-38663376 57 6.12e-05 GCCTAAGACC TCCCACAC CAGCCAGCCA chr20:31063417-31063497 59 6.12e-05 ACCCAGCAGC TCCCACAC CCGGAGTTCT chr22:29593212-29593292 50 6.12e-05 taaaaagaaa tcccacac ccatgagtgg chr19:11689147-11689227 11 6.12e-05 CCTCTCTCCA TCCCACAC ATAAACACCA chr17:43242839-43242919 56 6.12e-05 ATTTCCCATC TCCCACAC CCAGTACTCC chr7:95238154-95238234 11 6.12e-05 GAAAGGTCAG TCCCACAC CCACAGCCTG chr19:4679122-4679202 12 6.12e-05 GAGGCGCTGC TCCCACAC CGAGCCCCAC chr22:39378246-39378326 44 6.12e-05 CCCCGGGGCC TCCCACAC CAATGCCTGA chr14:100011529-10001160 19 6.12e-05 TGCCTGCCTC TCCCACAC ATCAGCTGCC chr19:15751529-15751609 43 6.12e-05 CCAGCTGGTC TCCCACAC CCAGGTTTTG chr3:57004528-57004608 34 6.12e-05 TGATAAGAAC TCCCACAC CTTCTGGCTT chr22:39410129-39410209 71 6.12e-05 CCCCGGGGCC TCCCACAC CA chr1:894805-894885 30 1.03e-04 CAGATGCGCC TCCCGCTC GGCGCCCGGC chr6:17706597-17706677 40 1.03e-04 CTCCGCCGCT TCCCGCTC CGGGGCGGGT chr21:45139345-45139425 68 1.03e-04 GGGATGAGCC TCCCGCTC TGCTT chr10:98592456-98592536 22 1.03e-04 ccgcccctgc tcccgctc caggcccggc chr5:56247362-56247442 21 1.03e-04 TGGCCCCGCA TCCCGCTC TTCTCCGCGC chr7:154982502-154982582 15 1.03e-04 GCGCTGGTTC TCCCGCTC CGGCCGCGGG chr17:48238901-48238981 56 1.03e-04 CGCCCCCGAC TCCCGCTC CGTCCCAACA chr20:57582146-57582226 71 1.03e-04 ccgctccgga tcccgctc cg chr19:19643372-19643452 52 1.23e-04 GAGTGTCCCA TCCCACTC TGTCCCCAGC chr20:31170986-31171066 17 1.23e-04 CGCTCGCGGC TCCCACTC CCCGCGGCCT chr3:9975034-9975114 19 1.42e-04 ACCCGCCCTT TTCCGCAC CGTGCCCGTC chr2:201374643-201374723 45 1.42e-04 CGCCCGGCTC TTCCGCAC CGGGGGGGTG chr4:5053211-5053291 34 2.39e-04 GCCTCGCGTC TCCCGCCC GCTGTAGCCG chr2:68870610-68870690 68 2.39e-04 ATCCGGACGC TCCCGCCC AGGGC chr9:107526389-107526469 14 2.39e-04 CCCCGCCGAG TCCCGCCC CTGCCTGAGT chr3:183354581-183354661 44 2.39e-04 AGGCGCGCGC TCCCGCCC CTGCTGCGGG chr14:50863636-50863716 5 2.39e-04 cggc tcccgccc cgggtctgcc chr3:184053751-184053831 10 2.81e-04 ACGCGCGGC TCCCACCC CTCCCCTCTC chr8:143696003-143696083 66 2.81e-04 GCTCCGTACC TCCCACCC CGGACGG chr2:87883897-87883977 24 2.81e-04 CCGGTGCTTC TCCCACCC CAGCCTGGAA chr19:7991489-7991569 52 2.81e-04 AGCCGCCTGC TCCCACCC CCACCATCGC chr22:43582852-43582932 4 2.81e-04 cgc tcccaccc cggccgccgc chr12:32832427-32832507 65 3.66e-04 CAGCGCCCAC TCCCGCGC CAGCCTTT chr5:102898220-102898300 31 3.66e-04 CGTCCGTGGC TCCCGCGC CTGCGCCCAC chr9:140512977-140513057 51 3.66e-04 CACAGGCGGC TCCCGCGC CAGGCCGCGG chr5:176449689-176449769 59 3.66e-04 AGATGGAGTA TCCCGCGC CGGCCACGGT chr3:187461699-187461779 24 3.66e-04 CGCCCGCTCC TCCCGCGC CGGGTCCCCT chr1:107600048-107600128 64 3.66e-04 GCTAGAGCTC TCCCGCGC CGGCTTGGA chr11:64052680-64052760 23 3.66e-04 GGGGGACACC TCCCGCGC CATCTCGGGG chr7:128050373-128050453 64 3.66e-04 ACCGCAGACC TCCCGCGC TGGGGCGAG chr1:230281953-230282033 68 3.66e-04 TTGGGAGGAG TCCCGCGC CTTCT chr11:129940529-12994060 1 3.66e-04 . TCCCGCGC CAGGCCGCCC chr19:9896629-9896709 73 4.05e-04 GCACTTCTGA TTCCGCTC chr6:32122290-32122370 42 4.05e-04 TGTTGCCATC TCCCTCAC ATGCCCTTAT chr10:35053700-35053780 3 4.05e-04 TT TCCCTCAC AAGTTGGCTC chr11:66671675-66671755 7 4.76e-04 CACCCC TCCTGCAC CCTGCCCCTT chr11:63974100-63974180 11 4.76e-04 GCAGTGTGCT TCCTGCAC CCAGCGCCAG chr9:107509946-107510026 53 4.76e-04 AGCCGCTCCT TTCCACTC GGGAAACCTT chr17:37823866-37823946 58 5.27e-04 GGCCCGGCTG TTCCGCCC GCTAAGTGCA chr6:44187300-44187380 57 5.27e-04 GCAGCCTCTC TTCCGCCC GGCGGCCCAC chr12:53268238-53268318 27 5.27e-04 CTGGCCTGCC TTCCGCCC CCTTCGCGTC chr5:137577870-137577950 32 5.27e-04 CCCCACGCAG TTCCGCCC GCGCCGGTGC chr2:172958001-172958081 55 5.67e-04 TGAAACCGGT TTCCACCC TTACCTTCTT chr2:152118141-152118221 19 6.47e-04 TCGCGCCCGG TTCCGCGC CCTTCTAGGG chr6:34425413-34425493 42 6.47e-04 aacccaggcc tcctgctc tacggagcag chr17:29035850-29035930 36 6.47e-04 GGAAGGAAAC TCCAGCAC GGGTTTTCGG chr1:1136927-1137007 29 6.47e-04 CACGAGGAGT TTCCGCGC TGAGTCAGCC chr19:55658433-55658513 70 6.47e-04 CTCCTCATAT TCCTGCTC CTC chr9:101002930-101003010 10 7.47e-04 AGGAACTGC TCCCTCCC TGACATGTCC chr17:3867759-3867839 14 7.47e-04 CGCCCGGGAC TCCCTccc cggggcgggg chr5:150143098-150143178 21 8.54e-04 TCTTCAGTGC TCCAGCTC AGGCTGAGGT -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCCCGCMC MEME-1 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr1:173991671-173991751 4.1e-05 57_[+1]_15 chr8:24858324-24858404 4.1e-05 51_[+1]_21 chr2:62732984-62733064 4.1e-05 52_[+1]_20 chr16:69165947-69166027 4.1e-05 32_[+1]_40 chr16:1381760-1381840 4.1e-05 40_[+1]_32 chr5:176882393-176882473 4.1e-05 39_[+1]_33 chr12:93965895-93965975 4.1e-05 46_[+1]_26 chr8:145987897-145987977 4.1e-05 9_[+1]_63 chr12:49659317-49659397 4.1e-05 57_[+1]_15 chr1:22668726-22668806 4.1e-05 19_[+1]_53 chr17:21118010-21118090 4.1e-05 16_[+1]_56 chr12:12503091-12503171 4.1e-05 48_[+1]_24 chr22:38663296-38663376 6.1e-05 56_[+1]_16 chr20:31063417-31063497 6.1e-05 58_[+1]_14 chr22:29593212-29593292 6.1e-05 49_[+1]_23 chr19:11689147-11689227 6.1e-05 10_[+1]_62 chr17:43242839-43242919 6.1e-05 55_[+1]_17 chr7:95238154-95238234 6.1e-05 10_[+1]_62 chr19:4679122-4679202 6.1e-05 11_[+1]_61 chr22:39378246-39378326 6.1e-05 43_[+1]_29 chr14:100011529-10001160 6.1e-05 18_[+1]_54 chr19:15751529-15751609 6.1e-05 42_[+1]_30 chr3:57004528-57004608 6.1e-05 33_[+1]_39 chr22:39410129-39410209 6.1e-05 70_[+1]_2 chr1:894805-894885 0.0001 29_[+1]_43 chr6:17706597-17706677 0.0001 39_[+1]_33 chr21:45139345-45139425 0.0001 67_[+1]_5 chr10:98592456-98592536 0.0001 21_[+1]_51 chr5:56247362-56247442 0.0001 20_[+1]_52 chr7:154982502-154982582 0.0001 14_[+1]_58 chr17:48238901-48238981 0.0001 55_[+1]_17 chr20:57582146-57582226 0.0001 70_[+1]_2 chr19:19643372-19643452 0.00012 51_[+1]_21 chr20:31170986-31171066 0.00012 16_[+1]_56 chr3:9975034-9975114 0.00014 18_[+1]_54 chr2:201374643-201374723 0.00014 44_[+1]_28 chr4:5053211-5053291 0.00024 33_[+1]_39 chr2:68870610-68870690 0.00024 67_[+1]_5 chr9:107526389-107526469 0.00024 13_[+1]_59 chr3:183354581-183354661 0.00024 43_[+1]_29 chr14:50863636-50863716 0.00024 4_[+1]_68 chr3:184053751-184053831 0.00028 9_[+1]_63 chr8:143696003-143696083 0.00028 65_[+1]_7 chr2:87883897-87883977 0.00028 23_[+1]_49 chr19:7991489-7991569 0.00028 51_[+1]_21 chr22:43582852-43582932 0.00028 3_[+1]_69 chr12:32832427-32832507 0.00037 64_[+1]_8 chr5:102898220-102898300 0.00037 30_[+1]_42 chr9:140512977-140513057 0.00037 50_[+1]_22 chr5:176449689-176449769 0.00037 58_[+1]_14 chr3:187461699-187461779 0.00037 23_[+1]_49 chr1:107600048-107600128 0.00037 63_[+1]_9 chr11:64052680-64052760 0.00037 22_[+1]_50 chr7:128050373-128050453 0.00037 63_[+1]_9 chr1:230281953-230282033 0.00037 67_[+1]_5 chr11:129940529-12994060 0.00037 [+1]_72 chr19:9896629-9896709 0.00041 72_[+1] chr6:32122290-32122370 0.00041 41_[+1]_31 chr10:35053700-35053780 0.00041 2_[+1]_70 chr11:66671675-66671755 0.00048 6_[+1]_66 chr11:63974100-63974180 0.00048 10_[+1]_62 chr9:107509946-107510026 0.00048 52_[+1]_20 chr17:37823866-37823946 0.00053 57_[+1]_15 chr6:44187300-44187380 0.00053 56_[+1]_16 chr12:53268238-53268318 0.00053 26_[+1]_46 chr5:137577870-137577950 0.00053 31_[+1]_41 chr2:172958001-172958081 0.00057 54_[+1]_18 chr2:152118141-152118221 0.00065 18_[+1]_54 chr6:34425413-34425493 0.00065 41_[+1]_31 chr17:29035850-29035930 0.00065 35_[+1]_37 chr1:1136927-1137007 0.00065 28_[+1]_44 chr19:55658433-55658513 0.00065 69_[+1]_3 chr9:101002930-101003010 0.00075 9_[+1]_63 chr17:3867759-3867839 0.00075 13_[+1]_59 chr5:150143098-150143178 0.00085 20_[+1]_52 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCCCGCMC MEME-1 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF TCCCGCMC width=8 seqs=75 chr1:173991671-173991751 ( 58) TCCCGCAC 1 chr8:24858324-24858404 ( 52) TCCCGCAC 1 chr2:62732984-62733064 ( 53) TCCCGCAC 1 chr16:69165947-69166027 ( 33) TCCCGCAC 1 chr16:1381760-1381840 ( 41) TCCCGCAC 1 chr5:176882393-176882473 ( 40) TCCCGCAC 1 chr12:93965895-93965975 ( 47) TCCCGCAC 1 chr8:145987897-145987977 ( 10) TCCCGCAC 1 chr12:49659317-49659397 ( 58) TCCCGCAC 1 chr1:22668726-22668806 ( 20) TCCCGCAC 1 chr17:21118010-21118090 ( 17) TCCCGCAC 1 chr12:12503091-12503171 ( 49) TCCCGCAC 1 chr22:38663296-38663376 ( 57) TCCCACAC 1 chr20:31063417-31063497 ( 59) TCCCACAC 1 chr22:29593212-29593292 ( 50) TCCCACAC 1 chr19:11689147-11689227 ( 11) TCCCACAC 1 chr17:43242839-43242919 ( 56) TCCCACAC 1 chr7:95238154-95238234 ( 11) TCCCACAC 1 chr19:4679122-4679202 ( 12) TCCCACAC 1 chr22:39378246-39378326 ( 44) TCCCACAC 1 chr14:100011529-10001160 ( 19) TCCCACAC 1 chr19:15751529-15751609 ( 43) TCCCACAC 1 chr3:57004528-57004608 ( 34) TCCCACAC 1 chr22:39410129-39410209 ( 71) TCCCACAC 1 chr1:894805-894885 ( 30) TCCCGCTC 1 chr6:17706597-17706677 ( 40) TCCCGCTC 1 chr21:45139345-45139425 ( 68) TCCCGCTC 1 chr10:98592456-98592536 ( 22) TCCCGCTC 1 chr5:56247362-56247442 ( 21) TCCCGCTC 1 chr7:154982502-154982582 ( 15) TCCCGCTC 1 chr17:48238901-48238981 ( 56) TCCCGCTC 1 chr20:57582146-57582226 ( 71) TCCCGCTC 1 chr19:19643372-19643452 ( 52) TCCCACTC 1 chr20:31170986-31171066 ( 17) TCCCACTC 1 chr3:9975034-9975114 ( 19) TTCCGCAC 1 chr2:201374643-201374723 ( 45) TTCCGCAC 1 chr4:5053211-5053291 ( 34) TCCCGCCC 1 chr2:68870610-68870690 ( 68) TCCCGCCC 1 chr9:107526389-107526469 ( 14) TCCCGCCC 1 chr3:183354581-183354661 ( 44) TCCCGCCC 1 chr14:50863636-50863716 ( 5) TCCCGCCC 1 chr3:184053751-184053831 ( 10) TCCCACCC 1 chr8:143696003-143696083 ( 66) TCCCACCC 1 chr2:87883897-87883977 ( 24) TCCCACCC 1 chr19:7991489-7991569 ( 52) TCCCACCC 1 chr22:43582852-43582932 ( 4) TCCCACCC 1 chr12:32832427-32832507 ( 65) TCCCGCGC 1 chr5:102898220-102898300 ( 31) TCCCGCGC 1 chr9:140512977-140513057 ( 51) TCCCGCGC 1 chr5:176449689-176449769 ( 59) TCCCGCGC 1 chr3:187461699-187461779 ( 24) TCCCGCGC 1 chr1:107600048-107600128 ( 64) TCCCGCGC 1 chr11:64052680-64052760 ( 23) TCCCGCGC 1 chr7:128050373-128050453 ( 64) TCCCGCGC 1 chr1:230281953-230282033 ( 68) TCCCGCGC 1 chr11:129940529-12994060 ( 1) TCCCGCGC 1 chr19:9896629-9896709 ( 73) TTCCGCTC 1 chr6:32122290-32122370 ( 42) TCCCTCAC 1 chr10:35053700-35053780 ( 3) TCCCTCAC 1 chr11:66671675-66671755 ( 7) TCCTGCAC 1 chr11:63974100-63974180 ( 11) TCCTGCAC 1 chr9:107509946-107510026 ( 53) TTCCACTC 1 chr17:37823866-37823946 ( 58) TTCCGCCC 1 chr6:44187300-44187380 ( 57) TTCCGCCC 1 chr12:53268238-53268318 ( 27) TTCCGCCC 1 chr5:137577870-137577950 ( 32) TTCCGCCC 1 chr2:172958001-172958081 ( 55) TTCCACCC 1 chr2:152118141-152118221 ( 19) TTCCGCGC 1 chr6:34425413-34425493 ( 42) TCCTGCTC 1 chr17:29035850-29035930 ( 36) TCCAGCAC 1 chr1:1136927-1137007 ( 29) TTCCGCGC 1 chr19:55658433-55658513 ( 70) TCCTGCTC 1 chr9:101002930-101003010 ( 10) TCCCTCCC 1 chr17:3867759-3867839 ( 14) TCCCTCCC 1 chr5:150143098-150143178 ( 21) TCCAGCTC 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCCCGCMC MEME-1 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 8.10161 E= 2.8e-015 -1287 -1287 -1287 262 -1287 132 -1287 -15 -1287 155 -1287 -1287 -261 143 -1287 -161 79 -1287 100 -161 -1287 155 -1287 -1287 135 -59 -106 29 -1287 155 -1287 -1287 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCCCGCMC MEME-1 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 75 E= 2.8e-015 0.000000 0.000000 0.000000 1.000000 0.000000 0.853333 0.000000 0.146667 0.000000 1.000000 0.000000 0.000000 0.026667 0.920000 0.000000 0.053333 0.280000 0.000000 0.666667 0.053333 0.000000 1.000000 0.000000 0.000000 0.413333 0.226667 0.160000 0.200000 0.000000 1.000000 0.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCCCGCMC MEME-1 regular expression -------------------------------------------------------------------------------- TCCC[GA]C[ACT]C -------------------------------------------------------------------------------- Time 5.19 secs. ******************************************************************************** ******************************************************************************** MOTIF GKGYGGGA MEME-2 width = 8 sites = 59 llr = 464 E-value = 3.1e-015 ******************************************************************************** -------------------------------------------------------------------------------- Motif GKGYGGGA MEME-2 Description -------------------------------------------------------------------------------- Simplified A :2:1:::a pos.-specific C :2:4:::: probability G a3a:aaa: matrix T :4:5:::: bits 2.6 * 2.4 * 2.1 * 1.8 * Relative 1.6 * * **** Entropy 1.3 * * **** (11.3 bits) 1.0 * * **** 0.8 * ****** 0.5 * ****** 0.3 ******** 0.0 -------- Multilevel GTGTGGGA consensus G C sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GKGYGGGA MEME-2 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr17:14204047-14204127 24 1.76e-05 ATGCGTGCGG GTGTGGGA GCGCACCACT chr1:228528803-228528883 5 1.76e-05 CATC GTGTGGGA GGGTGCACCG chr9:126116551-126116631 56 1.76e-05 CTCTGTGAAA GTGTGGGA GTTTGTGTCT chr9:101002930-101003010 55 1.76e-05 CACCCCTGGG GTGTGGGA AAGCACAGAA chr3:14167373-14167453 64 1.76e-05 AGGGCGCTGG GTGTGGGA GAAGCTGGT chr1:3458707-3458787 45 1.76e-05 TCCAGCCCCA GTGTGGGA AGGCAGCCCT chr5:150143098-150143178 46 1.76e-05 GGTGATGCTG GTGTGGGA GAGCCCAGCC chr8:142427874-142427954 43 1.76e-05 TAGGCGGCAG GTGTGGGA GCCCCCGGCA chr2:152117932-152118012 1 1.76e-05 . GTGTGGGA GGTGACAGCC chr2:74198168-74198248 62 1.76e-05 AAGGGGACCG GTGTGGGA CTTCTGCTCA chr1:100905811-100905891 56 1.76e-05 CTTGATCTTG GTGTGGGA GAGTCAGGAA chr17:55945650-55945730 20 1.76e-05 CTCCTCCCAG GTGTGGGA AAGGCCAGGG chr19:15291913-15291993 73 3.51e-05 ggagcggaag gagtggga chr6:20404137-20404217 26 3.51e-05 CGGGGTTTTG GAGTGGGA ACGGGGGGTT chr1:6266154-6266234 43 3.51e-05 GCCCCGCGCA GAGTGGGA ACCATCGCCC chr11:67141024-67141104 37 3.51e-05 GAGGCTGGCG GAGTGGGA GGGCGAGCCG chr19:41196452-41196532 60 7.21e-05 CCGGGGGATG GTGCGGGA TGCACGCGCG chr19:38747272-38747352 65 7.21e-05 GGGGCTGTTG GTGCGGGA GCGCCTGC chr17:80255889-80255969 44 7.21e-05 CGGGCGTGTG GTGCGGGA GCGTGTGTGT chr19:40005727-40005807 45 7.21e-05 TCAGAACCCG GTGCGGGA GACGCTCTCC chr10:71074970-71075050 34 7.21e-05 GTGCTCCCAG GTGCGGGA GGTACAGCTG chrX:46771626-46771706 48 7.21e-05 GGCGCCGCGG GTGCGGGA GCGGCGAGTG chr3:183354581-183354661 27 7.21e-05 GGTGGCGCGG GTGCGGGA GGCGCGCGCT chr2:27243368-27243448 38 1.08e-04 ttggcctctg gggtggga aggaggctca chr1:23730476-23730556 2 1.08e-04 G GGGTGGGA GGTTGGATTT chr13:30881702-30881782 27 1.08e-04 CAGCGGCGCG GGGTGGGA GAGCAGGGAG chr16:1349539-1349619 52 1.08e-04 CCGTCCCCCG GGGTGGGA GGACTACTGG chr5:415657-415737 1 1.08e-04 . GGGTGGGA GGCCTAGGGG chr8:15398185-15398265 30 1.08e-04 GGAGCCGCGA GGGTGGGA GGCCCTGGGG chr17:60770467-60770547 41 1.08e-04 CAACCTCCCA GGGTGGGA GCTGGGCCGG chr8:96080066-96080146 7 1.08e-04 ccatgg gggtggga gccttttgtc chr2:112123948-112124028 53 1.08e-04 TTCCAGGCTG GGGTGGGA GAAGCACCGG chr19:55658433-55658513 4 1.08e-04 CTG GGGTGGGA GAGCCTCTCC chr19:18549632-18549712 34 1.45e-04 TGATAAGGGA GCGTGGGA ACCCAGCGGG chr11:33061274-33061354 69 1.82e-04 TGGCAGGTGA GAGCGGGA GCTG chr10:6622466-6622546 25 1.82e-04 CTGCGAACTG GAGCGGGA GGCGGCGGCC chr3:193858705-193858785 68 1.82e-04 GCAGCATCCG GAGCGGGA AAGGC chrX:13707392-13707472 18 1.82e-04 GCCGCGAGGT GAGCGGGA CTCGGGACTC chr10:3088168-3088248 65 1.82e-04 GGCAGCCCTG GAGCGGGA GGCAGGGC chr6:17706597-17706677 62 2.57e-04 GCGGGTAAGG GGGCGGGA GAGGCAGAGG chr16:29823812-29823892 47 2.57e-04 CCCCAGAAAG GGGCGGGA GCGTCCTCGC chr1:184942839-184942919 36 2.57e-04 CCCCTCTCCG GGGCGGGA AGGGAACGGC chr5:139048087-139048167 72 2.57e-04 GCGTTTCTCG GGGCGGGA G chr7:95238154-95238234 28 2.57e-04 CCCACAGCCT GGGCGGGA CTGCCTGGCT chr10:92863612-92863692 68 2.75e-04 ACCAGCCCTG GTGAGGGA GAGGT chr21:45139345-45139425 54 3.53e-04 CTGGAGGCAG GCGCGGGA TGAGCCTCCC chr1:54955095-54955175 6 3.53e-04 GCGCA GCGCGGGA GCCCCCGGGC chr2:73297921-73298001 30 3.53e-04 gggggcccgg gcgcgggA GACCCTCCGC chr21:46274380-46274460 38 3.53e-04 CACAAACCCA GCGCGGGA GACACTAGAC chr1:150947409-150947489 1 3.53e-04 . GCGCGGGA GGCCAGACCC chr15:82339058-82339138 3 3.53e-04 CT GCGCGGGA GCGCACGAGA chr20:52210162-52210242 65 3.53e-04 ctcgggggcg gcgcggga gcctccgc chr1:65210301-65210381 30 3.53e-04 GGCCGCCCCA GCGCGGGA GTTTCGAGGG chr19:17727728-17727808 44 3.70e-04 TGTGCGCTCA GAGAGGGA CAGGAGACCG chr19:18402783-18402863 50 4.06e-04 CCAGGCCGAA GGGAGGGA AGTCGCAGTA chrX:153719222-153719302 20 4.06e-04 GACCCGCTCT GGGAGGGA GCCCCAGGCA chr10:71075171-71075251 10 4.14e-04 CCCCAACTT GTGTAGGA GGTACCACAG chr10:31607270-31607350 61 4.87e-04 GACAAGCACC GTGTGGGT ATTACTCATT chr11:18548152-18548232 73 4.87e-04 CTTCCGGCCC GTCTGGGA -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GKGYGGGA MEME-2 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr17:14204047-14204127 1.8e-05 23_[+2]_49 chr1:228528803-228528883 1.8e-05 4_[+2]_68 chr9:126116551-126116631 1.8e-05 55_[+2]_17 chr9:101002930-101003010 1.8e-05 54_[+2]_18 chr3:14167373-14167453 1.8e-05 63_[+2]_9 chr1:3458707-3458787 1.8e-05 44_[+2]_28 chr5:150143098-150143178 1.8e-05 45_[+2]_27 chr8:142427874-142427954 1.8e-05 42_[+2]_30 chr2:152117932-152118012 1.8e-05 [+2]_72 chr2:74198168-74198248 1.8e-05 61_[+2]_11 chr1:100905811-100905891 1.8e-05 55_[+2]_17 chr17:55945650-55945730 1.8e-05 19_[+2]_53 chr19:15291913-15291993 3.5e-05 72_[+2] chr6:20404137-20404217 3.5e-05 25_[+2]_47 chr1:6266154-6266234 3.5e-05 42_[+2]_30 chr11:67141024-67141104 3.5e-05 36_[+2]_36 chr19:41196452-41196532 7.2e-05 59_[+2]_13 chr19:38747272-38747352 7.2e-05 64_[+2]_8 chr17:80255889-80255969 7.2e-05 43_[+2]_29 chr19:40005727-40005807 7.2e-05 44_[+2]_28 chr10:71074970-71075050 7.2e-05 33_[+2]_39 chrX:46771626-46771706 7.2e-05 47_[+2]_25 chr3:183354581-183354661 7.2e-05 26_[+2]_46 chr2:27243368-27243448 0.00011 37_[+2]_35 chr1:23730476-23730556 0.00011 1_[+2]_71 chr13:30881702-30881782 0.00011 26_[+2]_46 chr16:1349539-1349619 0.00011 51_[+2]_21 chr5:415657-415737 0.00011 [+2]_72 chr8:15398185-15398265 0.00011 29_[+2]_43 chr17:60770467-60770547 0.00011 40_[+2]_32 chr8:96080066-96080146 0.00011 6_[+2]_66 chr2:112123948-112124028 0.00011 52_[+2]_20 chr19:55658433-55658513 0.00011 3_[+2]_69 chr19:18549632-18549712 0.00015 33_[+2]_39 chr11:33061274-33061354 0.00018 68_[+2]_4 chr10:6622466-6622546 0.00018 24_[+2]_48 chr3:193858705-193858785 0.00018 67_[+2]_5 chrX:13707392-13707472 0.00018 17_[+2]_55 chr10:3088168-3088248 0.00018 64_[+2]_8 chr6:17706597-17706677 0.00026 61_[+2]_11 chr16:29823812-29823892 0.00026 46_[+2]_26 chr1:184942839-184942919 0.00026 35_[+2]_37 chr5:139048087-139048167 0.00026 71_[+2]_1 chr7:95238154-95238234 0.00026 27_[+2]_45 chr10:92863612-92863692 0.00027 67_[+2]_5 chr21:45139345-45139425 0.00035 53_[+2]_19 chr1:54955095-54955175 0.00035 5_[+2]_67 chr2:73297921-73298001 0.00035 29_[+2]_43 chr21:46274380-46274460 0.00035 37_[+2]_35 chr1:150947409-150947489 0.00035 [+2]_72 chr15:82339058-82339138 0.00035 2_[+2]_70 chr20:52210162-52210242 0.00035 64_[+2]_8 chr1:65210301-65210381 0.00035 29_[+2]_43 chr19:17727728-17727808 0.00037 43_[+2]_29 chr19:18402783-18402863 0.00041 49_[+2]_23 chrX:153719222-153719302 0.00041 19_[+2]_53 chr10:71075171-71075251 0.00041 9_[+2]_63 chr10:31607270-31607350 0.00049 60_[+2]_12 chr11:18548152-18548232 0.00049 72_[+2] -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GKGYGGGA MEME-2 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF GKGYGGGA width=8 seqs=59 chr17:14204047-14204127 ( 24) GTGTGGGA 1 chr1:228528803-228528883 ( 5) GTGTGGGA 1 chr9:126116551-126116631 ( 56) GTGTGGGA 1 chr9:101002930-101003010 ( 55) GTGTGGGA 1 chr3:14167373-14167453 ( 64) GTGTGGGA 1 chr1:3458707-3458787 ( 45) GTGTGGGA 1 chr5:150143098-150143178 ( 46) GTGTGGGA 1 chr8:142427874-142427954 ( 43) GTGTGGGA 1 chr2:152117932-152118012 ( 1) GTGTGGGA 1 chr2:74198168-74198248 ( 62) GTGTGGGA 1 chr1:100905811-100905891 ( 56) GTGTGGGA 1 chr17:55945650-55945730 ( 20) GTGTGGGA 1 chr19:15291913-15291993 ( 73) GAGTGGGA 1 chr6:20404137-20404217 ( 26) GAGTGGGA 1 chr1:6266154-6266234 ( 43) GAGTGGGA 1 chr11:67141024-67141104 ( 37) GAGTGGGA 1 chr19:41196452-41196532 ( 60) GTGCGGGA 1 chr19:38747272-38747352 ( 65) GTGCGGGA 1 chr17:80255889-80255969 ( 44) GTGCGGGA 1 chr19:40005727-40005807 ( 45) GTGCGGGA 1 chr10:71074970-71075050 ( 34) GTGCGGGA 1 chrX:46771626-46771706 ( 48) GTGCGGGA 1 chr3:183354581-183354661 ( 27) GTGCGGGA 1 chr2:27243368-27243448 ( 38) GGGTGGGA 1 chr1:23730476-23730556 ( 2) GGGTGGGA 1 chr13:30881702-30881782 ( 27) GGGTGGGA 1 chr16:1349539-1349619 ( 52) GGGTGGGA 1 chr5:415657-415737 ( 1) GGGTGGGA 1 chr8:15398185-15398265 ( 30) GGGTGGGA 1 chr17:60770467-60770547 ( 41) GGGTGGGA 1 chr8:96080066-96080146 ( 7) GGGTGGGA 1 chr2:112123948-112124028 ( 53) GGGTGGGA 1 chr19:55658433-55658513 ( 4) GGGTGGGA 1 chr19:18549632-18549712 ( 34) GCGTGGGA 1 chr11:33061274-33061354 ( 69) GAGCGGGA 1 chr10:6622466-6622546 ( 25) GAGCGGGA 1 chr3:193858705-193858785 ( 68) GAGCGGGA 1 chrX:13707392-13707472 ( 18) GAGCGGGA 1 chr10:3088168-3088248 ( 65) GAGCGGGA 1 chr6:17706597-17706677 ( 62) GGGCGGGA 1 chr16:29823812-29823892 ( 47) GGGCGGGA 1 chr1:184942839-184942919 ( 36) GGGCGGGA 1 chr5:139048087-139048167 ( 72) GGGCGGGA 1 chr7:95238154-95238234 ( 28) GGGCGGGA 1 chr10:92863612-92863692 ( 68) GTGAGGGA 1 chr21:45139345-45139425 ( 54) GCGCGGGA 1 chr1:54955095-54955175 ( 6) GCGCGGGA 1 chr2:73297921-73298001 ( 30) GCGCGGGA 1 chr21:46274380-46274460 ( 38) GCGCGGGA 1 chr1:150947409-150947489 ( 1) GCGCGGGA 1 chr15:82339058-82339138 ( 3) GCGCGGGA 1 chr20:52210162-52210242 ( 65) GCGCGGGA 1 chr1:65210301-65210381 ( 30) GCGCGGGA 1 chr19:17727728-17727808 ( 44) GAGAGGGA 1 chr19:18402783-18402863 ( 50) GGGAGGGA 1 chrX:153719222-153719302 ( 20) GGGAGGGA 1 chr10:71075171-71075251 ( 10) GTGTAGGA 1 chr10:31607270-31607350 ( 61) GTGTGGGT 1 chr11:18548152-18548232 ( 73) GTCTGGGA 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GKGYGGGA MEME-2 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 9.53308 E= 3.1e-015 -1253 -1253 159 -1253 6 -116 -21 126 -1253 -433 156 -1253 -126 31 -1253 164 -326 -1253 156 -1253 -1253 -1253 159 -1253 -1253 -1253 159 -1253 260 -1253 -1253 -326 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GKGYGGGA MEME-2 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 59 E= 3.1e-015 0.000000 0.000000 1.000000 0.000000 0.169492 0.152542 0.288136 0.389831 0.000000 0.016949 0.983051 0.000000 0.067797 0.423729 0.000000 0.508475 0.016949 0.000000 0.983051 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.983051 0.000000 0.000000 0.016949 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GKGYGGGA MEME-2 regular expression -------------------------------------------------------------------------------- G[TG]G[TC]GGGA -------------------------------------------------------------------------------- Time 8.93 secs. ******************************************************************************** ******************************************************************************** MOTIF TWTAWWWA MEME-3 width = 8 sites = 18 llr = 175 E-value = 1.1e-002 ******************************************************************************** -------------------------------------------------------------------------------- Motif TWTAWWWA MEME-3 Description -------------------------------------------------------------------------------- Simplified A :3:94459 pos.-specific C 11:::1:: probability G ::::1::: matrix T 96a14451 bits 2.6 * 2.4 * 2.1 * ** * 1.8 * ** * Relative 1.6 * ** ** Entropy 1.3 **** ** (14.1 bits) 1.0 ******** 0.8 ******** 0.5 ******** 0.3 ******** 0.0 -------- Multilevel TTTAAAAA consensus A TTT sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TWTAWWWA MEME-3 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr1:151430813-151430893 25 3.90e-06 CTCATTCCAT TTTATAAA TCACGGCGCC chr17:45955143-45955223 30 3.90e-06 ACTCGGCTGC TTTATTTA TGGGCCCGGT chr11:67141024-67141104 70 3.90e-06 CCGGCGAAGC TTTAATAA TCC chr8:142426083-142426163 7 7.78e-06 CCTGGT TATAAATA GACTTCTCCG chr19:3036395-3036475 11 7.78e-06 CCCGGCGCGG TATAATTA CAGCCCATTG chr8:142427874-142427954 27 7.78e-06 AGGGCGCGGC TATATTTA GGCGGCAGGT chr22:19706615-19706695 24 7.78e-06 cgccgcggTC TATAAATA GGCGCTGCTc chr18:77267150-77267230 65 1.18e-05 CTGCTGTTAT TTTAGATA TGGCAGGA chr1:23730476-23730556 17 2.37e-05 GGAGGTTGGA TTTATCAA CAGCTTCCTT chr10:92863612-92863692 25 2.37e-05 ACTGTATGCG TTTATTAT CTCACAAGAG chr21:46274380-46274460 67 2.37e-05 CTTTGCGGAC TTTAAAAT CATACA chr4:185517915-185517995 1 2.37e-05 . TTTAACAA CCAGGTGTGA chr11:129940529-12994060 60 2.37e-05 CGGACGCGCA TTTTTTAA GTGGCGCTGT chr10:35053700-35053780 47 2.77e-05 AGACAGCTCT TATAGATA AGCACCTGGC chr17:43242839-43242919 5 3.96e-05 TGGT TATTATTA GAAATTGCCC chr1:7844151-7844231 63 4.78e-05 cTCGCCCTGG CTTATATA ACCCGGGCGC chrX:47796097-47796177 61 4.78e-05 aacagtgggt cttaataa gcacattcct chr19:59055532-59055612 38 5.60e-05 GGAATCACAC TCTATAAA GGTTCGCATA -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TWTAWWWA MEME-3 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr1:151430813-151430893 3.9e-06 24_[+3]_48 chr17:45955143-45955223 3.9e-06 29_[+3]_43 chr11:67141024-67141104 3.9e-06 69_[+3]_3 chr8:142426083-142426163 7.8e-06 6_[+3]_66 chr19:3036395-3036475 7.8e-06 10_[+3]_62 chr8:142427874-142427954 7.8e-06 26_[+3]_46 chr22:19706615-19706695 7.8e-06 23_[+3]_49 chr18:77267150-77267230 1.2e-05 64_[+3]_8 chr1:23730476-23730556 2.4e-05 16_[+3]_56 chr10:92863612-92863692 2.4e-05 24_[+3]_48 chr21:46274380-46274460 2.4e-05 66_[+3]_6 chr4:185517915-185517995 2.4e-05 [+3]_72 chr11:129940529-12994060 2.4e-05 59_[+3]_13 chr10:35053700-35053780 2.8e-05 46_[+3]_26 chr17:43242839-43242919 4e-05 4_[+3]_68 chr1:7844151-7844231 4.8e-05 62_[+3]_10 chrX:47796097-47796177 4.8e-05 60_[+3]_12 chr19:59055532-59055612 5.6e-05 37_[+3]_35 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TWTAWWWA MEME-3 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF TWTAWWWA width=8 seqs=18 chr1:151430813-151430893 ( 25) TTTATAAA 1 chr17:45955143-45955223 ( 30) TTTATTTA 1 chr11:67141024-67141104 ( 70) TTTAATAA 1 chr8:142426083-142426163 ( 7) TATAAATA 1 chr19:3036395-3036475 ( 11) TATAATTA 1 chr8:142427874-142427954 ( 27) TATATTTA 1 chr22:19706615-19706695 ( 24) TATAAATA 1 chr18:77267150-77267230 ( 65) TTTAGATA 1 chr1:23730476-23730556 ( 17) TTTATCAA 1 chr10:92863612-92863692 ( 25) TTTATTAT 1 chr21:46274380-46274460 ( 67) TTTAAAAT 1 chr4:185517915-185517995 ( 1) TTTAACAA 1 chr11:129940529-12994060 ( 60) TTTTTTAA 1 chr10:35053700-35053780 ( 47) TATAGATA 1 chr17:43242839-43242919 ( 5) TATTATTA 1 chr1:7844151-7844231 ( 63) CTTATATA 1 chrX:47796097-47796177 ( 61) CTTAATAA 1 chr19:59055532-59055612 ( 38) TCTATAAA 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TWTAWWWA MEME-3 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 11.7767 E= 1.1e-002 -1081 -162 -1081 244 104 -262 -1081 190 -1081 -1081 -1081 261 245 -1081 -1081 -55 145 -1081 -158 145 145 -162 -1081 145 162 -1081 -1081 162 245 -1081 -1081 -55 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TWTAWWWA MEME-3 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 18 E= 1.1e-002 0.000000 0.111111 0.000000 0.888889 0.333333 0.055556 0.000000 0.611111 0.000000 0.000000 0.000000 1.000000 0.888889 0.000000 0.000000 0.111111 0.444444 0.000000 0.111111 0.444444 0.444444 0.111111 0.000000 0.444444 0.500000 0.000000 0.000000 0.500000 0.888889 0.000000 0.000000 0.111111 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TWTAWWWA MEME-3 regular expression -------------------------------------------------------------------------------- T[TA]TA[AT][AT][AT]A -------------------------------------------------------------------------------- Time 12.56 secs. ******************************************************************************** ******************************************************************************** MOTIF AGAAARAW MEME-4 width = 8 sites = 17 llr = 162 E-value = 3.6e+000 ******************************************************************************** -------------------------------------------------------------------------------- Motif AGAAARAW MEME-4 Description -------------------------------------------------------------------------------- Simplified A 919a8585 pos.-specific C ::1::1:: probability G :9::242: matrix T 1::::::5 bits 2.6 * 2.4 * 2.1 * ** 1.8 * *** * Relative 1.6 * *** ** Entropy 1.3 ***** ** (13.8 bits) 1.0 ***** ** 0.8 ******** 0.5 ******** 0.3 ******** 0.0 -------- Multilevel AGAAAAAA consensus G T sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AGAAARAW MEME-4 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr10:74036574-74036654 30 1.96e-06 gttccttgtc agaaaaat tggcaaattg chr6:20404137-20404217 70 1.96e-06 TGAGTAAGCA AGAAAAAT CTA chr20:31063417-31063497 40 5.98e-06 TGTAAAACCA AGAAAGAT GACCCAGCAG chr4:185517915-185517995 22 5.98e-06 GGTGTGACAC AGAAAGAT AACACAGACC chr2:172958001-172958081 38 8.90e-06 TCCAACCCTC TGAAAAAT GAAACCGGTT chr2:27229633-27229713 72 1.70e-05 tgccatcttc agaaaaga a chr16:1381760-1381840 9 1.70e-05 ccctacct agaaaaga gtggggaGAG chr10:49515131-49515211 39 1.70e-05 CCGCGGCGGG AGAAGAAA ATGGAGCGGG chr22:39378246-39378326 20 1.70e-05 CCAGAGCCAG AGAAACAT GAAGCACCCC chr3:195181230-195181310 57 1.70e-05 CCACCTTACT AGAAAAGA TAAGCTCCCT chr22:39410129-39410209 47 1.70e-05 CCAGAGCCAG AGAAACAT GAAGCACCCC chr22:29593212-29593292 41 2.20e-05 tcatcaccct aaaaagaa atcccacacc chr19:17727728-17727808 63 2.72e-05 AGGAGACCGA AGCAAAAT ACAGAGAGAA chr8:96080066-96080146 34 2.92e-05 cagatgggga tgaaagaa ccagctccct chr22:38663296-38663376 1 4.04e-05 . AGAAGGAA AAGGAGGTGT chr1:151430813-151430893 48 5.26e-05 GCGCCATCCC AAAAGAAA TTTGGGGACC chr7:47514956-47515036 4 5.88e-05 CCA AGCAAGAA CAATCACAGC -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AGAAARAW MEME-4 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr10:74036574-74036654 2e-06 29_[+4]_43 chr6:20404137-20404217 2e-06 69_[+4]_3 chr20:31063417-31063497 6e-06 39_[+4]_33 chr4:185517915-185517995 6e-06 21_[+4]_51 chr2:172958001-172958081 8.9e-06 37_[+4]_35 chr2:27229633-27229713 1.7e-05 71_[+4]_1 chr16:1381760-1381840 1.7e-05 8_[+4]_64 chr10:49515131-49515211 1.7e-05 38_[+4]_34 chr22:39378246-39378326 1.7e-05 19_[+4]_53 chr3:195181230-195181310 1.7e-05 56_[+4]_16 chr22:39410129-39410209 1.7e-05 46_[+4]_26 chr22:29593212-29593292 2.2e-05 40_[+4]_32 chr19:17727728-17727808 2.7e-05 62_[+4]_10 chr8:96080066-96080146 2.9e-05 33_[+4]_39 chr22:38663296-38663376 4e-05 [+4]_72 chr1:151430813-151430893 5.3e-05 47_[+4]_25 chr7:47514956-47515036 5.9e-05 3_[+4]_69 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AGAAARAW MEME-4 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF AGAAARAW width=8 seqs=17 chr10:74036574-74036654 ( 30) AGAAAAAT 1 chr6:20404137-20404217 ( 70) AGAAAAAT 1 chr20:31063417-31063497 ( 40) AGAAAGAT 1 chr4:185517915-185517995 ( 22) AGAAAGAT 1 chr2:172958001-172958081 ( 38) TGAAAAAT 1 chr2:27229633-27229713 ( 72) AGAAAAGA 1 chr16:1381760-1381840 ( 9) AGAAAAGA 1 chr10:49515131-49515211 ( 39) AGAAGAAA 1 chr22:39378246-39378326 ( 20) AGAAACAT 1 chr3:195181230-195181310 ( 57) AGAAAAGA 1 chr22:39410129-39410209 ( 47) AGAAACAT 1 chr22:29593212-29593292 ( 41) AAAAAGAA 1 chr19:17727728-17727808 ( 63) AGCAAAAT 1 chr8:96080066-96080146 ( 34) TGAAAGAA 1 chr22:38663296-38663376 ( 1) AGAAGGAA 1 chr1:151430813-151430893 ( 48) AAAAGAAA 1 chr7:47514956-47515036 ( 4) AGCAAGAA 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AGAAARAW MEME-4 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 10.8621 E= 3.6e+000 244 -1073 -1073 -47 -46 -1073 141 -1073 244 -154 -1073 -1073 262 -1073 -1073 -1073 234 -1073 -92 -1073 170 -154 8 -1073 234 -1073 -92 -1073 170 -1073 -1073 153 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AGAAARAW MEME-4 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 17 E= 3.6e+000 0.882353 0.000000 0.000000 0.117647 0.117647 0.000000 0.882353 0.000000 0.882353 0.117647 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.823529 0.000000 0.176471 0.000000 0.529412 0.117647 0.352941 0.000000 0.823529 0.000000 0.176471 0.000000 0.529412 0.000000 0.000000 0.470588 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AGAAARAW MEME-4 regular expression -------------------------------------------------------------------------------- AGAAA[AG]A[AT] -------------------------------------------------------------------------------- Time 16.15 secs. ******************************************************************************** ******************************************************************************** MOTIF YTTGTTTY MEME-5 width = 8 sites = 10 llr = 107 E-value = 1.1e+002 ******************************************************************************** -------------------------------------------------------------------------------- Motif YTTGTTTY MEME-5 Description -------------------------------------------------------------------------------- Simplified A ::1:1::: pos.-specific C 4::::::5 probability G :::7:::: matrix T 6a939aa5 bits 2.6 * ** 2.4 * ** 2.1 ** *** 1.8 ** *** Relative 1.6 ** *** Entropy 1.3 *** *** (15.5 bits) 1.0 ******** 0.8 ******** 0.5 ******** 0.3 ******** 0.0 -------- Multilevel TTTGTTTC consensus C T T sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YTTGTTTY MEME-5 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr15:78730411-78730491 52 1.02e-06 CTTCCCTTTC TTTGTTTT CCTGTCCGAC chr18:72921267-72921347 21 1.02e-06 CTTTAATCTT TTTGTTTT GGTTTGAATC chr8:142427874-142427954 3 3.65e-06 CC TTTGTTTC CCGGGCAGGG chr10:72994911-72994991 16 4.70e-06 GCCGGAGTGC TTTTTTTC CTCCTTCTTT chr8:144100466-144100546 44 6.83e-06 GCCCCCGCTT CTTGTTTT GGCACTGGTG chr5:134370266-134370346 9 1.24e-05 TCAAATGA CTTGTTTC GCCTAGAATC chr10:103880679-10388075 20 1.24e-05 CTGGAGGCCC CTTGTTTC GCGTCCCTAC chr9:107526389-107526469 53 1.46e-05 CCAGGAGCCG CTTTTTTC CACTCGGGAA chr16:3070075-3070155 45 1.66e-05 GTGTCTAATT TTTGATTT CCCCACACCA chr1:230281953-230282033 2 1.76e-05 G TTATTTTT CCCCTCCCTT -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YTTGTTTY MEME-5 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr15:78730411-78730491 1e-06 51_[+5]_21 chr18:72921267-72921347 1e-06 20_[+5]_52 chr8:142427874-142427954 3.7e-06 2_[+5]_70 chr10:72994911-72994991 4.7e-06 15_[+5]_57 chr8:144100466-144100546 6.8e-06 43_[+5]_29 chr5:134370266-134370346 1.2e-05 8_[+5]_64 chr10:103880679-10388075 1.2e-05 19_[+5]_53 chr9:107526389-107526469 1.5e-05 52_[+5]_20 chr16:3070075-3070155 1.7e-05 44_[+5]_28 chr1:230281953-230282033 1.8e-05 1_[+5]_71 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YTTGTTTY MEME-5 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF YTTGTTTY width=8 seqs=10 chr15:78730411-78730491 ( 52) TTTGTTTT 1 chr18:72921267-72921347 ( 21) TTTGTTTT 1 chr8:142427874-142427954 ( 3) TTTGTTTC 1 chr10:72994911-72994991 ( 16) TTTTTTTC 1 chr8:144100466-144100546 ( 44) CTTGTTTT 1 chr5:134370266-134370346 ( 9) CTTGTTTC 1 chr10:103880679-10388075 ( 20) CTTGTTTC 1 chr9:107526389-107526469 ( 53) CTTTTTTC 1 chr16:3070075-3070155 ( 45) TTTGATTT 1 chr1:230281953-230282033 ( 2) TTATTTTT 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YTTGTTTY MEME-5 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 12.3073 E= 1.1e+002 -997 23 -997 188 -997 -997 -997 261 -70 -997 -997 246 -997 -997 107 88 -70 -997 -997 246 -997 -997 -997 261 -997 -997 -997 261 -997 55 -997 161 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YTTGTTTY MEME-5 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 10 E= 1.1e+002 0.000000 0.400000 0.000000 0.600000 0.000000 0.000000 0.000000 1.000000 0.100000 0.000000 0.000000 0.900000 0.000000 0.000000 0.700000 0.300000 0.100000 0.000000 0.000000 0.900000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.500000 0.000000 0.500000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YTTGTTTY MEME-5 regular expression -------------------------------------------------------------------------------- [TC]TT[GT]TTT[CT] -------------------------------------------------------------------------------- Time 19.70 secs. ******************************************************************************** ******************************************************************************** SUMMARY OF MOTIFS ******************************************************************************** -------------------------------------------------------------------------------- Combined block diagrams: non-overlapping sites with p-value < 0.0001 -------------------------------------------------------------------------------- SEQUENCE NAME COMBINED P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr1:98386703-98386783 2.23e-02 80 chr19:55658433-55658513 5.37e-03 80 chr10:103880462-10388054 9.94e-01 80 chr17:1388318-1388398 5.15e-01 80 chr1:65210301-65210381 2.47e-01 80 chr14:24439169-24439249 2.17e-01 80 chr11:129940529-12994060 5.01e-04 59_[+3(2.37e-05)]_13 chr2:112123948-112124028 1.38e-02 80 chr4:187645808-187645888 8.87e-01 80 chr8:81083858-81083938 9.93e-01 80 chr22:43582852-43582932 6.17e-02 80 chr20:62370732-62370812 5.06e-01 80 chr1:9884537-9884617 5.61e-01 80 chr12:12503091-12503171 5.09e-02 48_[+1(4.11e-05)]_24 chr1:156647271-156647351 2.44e-01 80 chr20:57582146-57582226 2.51e-01 80 chr20:52210162-52210242 5.47e-01 80 chr2:73297718-73297798 5.85e-01 80 chr17:55945650-55945730 1.12e-01 19_[+2(1.76e-05)]_53 chr1:230281953-230282033 2.46e-04 1_[+5(1.76e-05)]_71 chr15:82339058-82339138 9.34e-02 80 chr8:96080066-96080146 6.21e-05 33_[+4(2.92e-05)]_39 chr19:7991489-7991569 6.29e-01 80 chr19:51326744-51326824 1.95e-01 80 chr12:65063434-65063514 1.36e-01 80 chr12:25404331-25404411 4.50e-01 80 chr1:52456273-52456353 8.89e-01 80 chr10:103880679-10388075 2.23e-04 19_[+5(1.24e-05)]_53 chr20:31170986-31171066 3.44e-01 80 chr22:39410129-39410209 1.65e-03 46_[+4(1.70e-05)]_16_[+1(6.12e-05)]_\ 2 chr5:137577870-137577950 4.04e-01 80 chr17:60770467-60770547 8.02e-02 80 chr3:57004528-57004608 1.04e-02 33_[+1(6.12e-05)]_39 chr8:15398185-15398265 5.55e-02 80 chr19:15751529-15751609 1.20e-01 42_[+1(6.12e-05)]_30 chr14:100011529-10001160 2.48e-01 18_[+1(6.12e-05)]_54 chr17:40761172-40761252 9.72e-01 80 chr3:195181230-195181310 2.72e-02 25_[+4(1.70e-05)]_23_[+4(1.70e-05)]_\ 16 chr7:128050373-128050453 3.87e-01 80 chr4:85503957-85504037 8.50e-01 80 chr1:150947409-150947489 6.51e-02 80 chr5:415657-415737 3.53e-01 80 chr21:46862753-46862833 9.45e-01 80 chr14:50863636-50863716 3.06e-01 80 chr4:185517915-185517995 2.17e-04 [+3(2.37e-05)]_13_[+4(5.98e-06)]_51 chr3:183354581-183354661 2.88e-02 26_[+2(7.21e-05)]_46 chr10:88281945-88282025 7.46e-01 80 chr1:956504-956584 6.67e-02 80 chr17:42296713-42296793 9.37e-01 80 chrX:46771626-46771706 3.08e-01 47_[+2(7.21e-05)]_25 chr18:28681402-28681482 8.90e-01 80 chr17:48238901-48238981 3.12e-01 80 chr22:39378246-39378326 3.15e-04 19_[+4(1.70e-05)]_16_[+1(6.12e-05)]_\ 29 chr10:35053700-35053780 1.18e-03 46_[+3(2.77e-05)]_26 chr17:38477488-38477568 3.71e-02 80 chr17:79386717-79386797 4.72e-01 80 chr1:100905811-100905891 2.58e-03 55_[+2(1.76e-05)]_17 chr9:137217753-137217833 6.65e-01 80 chr2:87883897-87883977 5.81e-02 80 chr16:1349539-1349619 1.96e-01 80 chr12:25404536-25404616 5.77e-02 80 chr17:21118010-21118090 2.31e-02 16_[+1(4.11e-05)]_56 chr8:144100466-144100546 9.83e-03 43_[+5(6.83e-06)]_29 chr10:72994911-72994991 1.56e-03 15_[+5(4.70e-06)]_57 chr10:71074970-71075050 1.31e-02 33_[+2(7.21e-05)]_39 chr9:107526389-107526469 6.45e-04 52_[+5(1.46e-05)]_20 chr19:4679122-4679202 1.78e-01 11_[+1(6.12e-05)]_61 chr11:65405646-65405726 8.33e-01 80 chr4:153945304-153945384 6.64e-01 80 chr10:71892472-71892552 4.34e-01 80 chr7:95238154-95238234 7.80e-04 10_[+1(6.12e-05)]_62 chr10:3088168-3088248 1.23e-01 80 chr21:46274380-46274460 1.00e-03 66_[+3(2.37e-05)]_6 chr2:74198168-74198248 8.74e-03 61_[+2(1.76e-05)]_11 chr13:49550374-49550454 7.30e-01 80 chr17:39705232-39705312 8.81e-01 80 chr2:68870610-68870690 1.83e-01 80 chr4:1795183-1795263 9.95e-01 80 chr7:30810795-30810875 6.23e-01 80 chr7:158656077-158656157 2.54e-01 80 chr16:838694-838774 1.42e-01 80 chrX:24043936-24044016 9.38e-01 80 chr7:154982502-154982582 9.13e-02 80 chr12:29301902-29301982 3.97e-01 80 chr18:72921267-72921347 4.12e-04 20_[+5(1.02e-06)]_52 chr19:40005727-40005807 6.54e-02 44_[+2(7.21e-05)]_28 chr4:85504180-85504260 2.70e-01 80 chr11:67141024-67141104 4.52e-04 36_[+2(3.51e-05)]_25_[+3(3.90e-06)]_\ 3 chr1:22668726-22668806 5.46e-02 19_[+1(4.11e-05)]_53 chr1:1136927-1137007 4.08e-01 80 chr9:107509946-107510026 1.44e-01 80 chr22:19706615-19706695 5.86e-02 23_[+3(7.78e-06)]_49 chr2:152117932-152118012 3.57e-02 [+2(1.76e-05)]_72 chr12:6977067-6977147 2.87e-01 80 chr8:48651494-48651574 9.51e-01 80 chr2:172958001-172958081 2.06e-03 37_[+4(8.90e-06)]_35 chr5:139048087-139048167 3.22e-01 80 chr2:201374643-201374723 1.60e-01 80 chr17:29035850-29035930 1.66e-01 80 chr13:30881702-30881782 8.89e-02 80 chr11:64052680-64052760 4.44e-02 80 chr17:80255889-80255969 1.92e-02 43_[+2(7.21e-05)]_29 chr19:17727728-17727808 2.68e-03 62_[+4(2.72e-05)]_10 chr10:49515131-49515211 4.71e-03 38_[+4(1.70e-05)]_34 chr11:63974100-63974180 6.70e-02 80 chr11:46403548-46403628 5.13e-01 80 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