******************************************************************************** MEME - Motif discovery tool ******************************************************************************** MEME version 5.3.3 (Release date: Sun Feb 7 15:39:52 2021 -0800) For further information on how to interpret these results please access https://meme-suite.org/meme. To get a copy of the MEME Suite software please access https://meme-suite.org. ******************************************************************************** ******************************************************************************** REFERENCE ******************************************************************************** If you use this program in your research, please cite: Timothy L. Bailey and Charles Elkan, "Fitting a mixture model by expectation maximization to discover motifs in biopolymers", Proceedings of the Second International Conference on Intelligent Systems for Molecular Biology, pp. 28-36, AAAI Press, Menlo Park, California, 1994. ******************************************************************************** ******************************************************************************** TRAINING SET ******************************************************************************** PRIMARY SEQUENCES= ../result/final_prediction/K562/fasta/RankLinear0.6_40/ZNF175.fasta CONTROL SEQUENCES= --none-- ALPHABET= ACGT Sequence name Weight Length Sequence name Weight Length ------------- ------ ------ ------------- ------ ------ chr3:40309932-40310012 1.0000 80 chr20:31840425-31840505 1.0000 80 chr4:26932838-26932918 1.0000 80 chr6:4829496-4829576 1.0000 80 chr7:64766111-64766191 1.0000 80 chr17:61373662-61373742 1.0000 80 chr9:95057751-95057831 1.0000 80 chr11:74136304-74136384 1.0000 80 chr4:89961241-89961321 1.0000 80 chr9:96950689-96950769 1.0000 80 chrX:38629617-38629697 1.0000 80 chr17:71221275-71221355 1.0000 80 chr7:7214809-7214889 1.0000 80 chr9:115981629-115981709 1.0000 80 chr20:45318991-45319071 1.0000 80 chr12:108653975-10865405 1.0000 80 chr3:17756095-17756175 1.0000 80 chr9:6210125-6210205 1.0000 80 chr1:236673375-236673455 1.0000 80 chr8:49944967-49945047 1.0000 80 chr3:5157424-5157504 1.0000 80 chr12:116837019-11683709 1.0000 80 chr17:42730257-42730337 1.0000 80 chr1:9138482-9138562 1.0000 80 chr16:22365055-22365135 1.0000 80 chr1:234472254-234472334 1.0000 80 chr2:26055925-26056005 1.0000 80 chr6:25866424-25866504 1.0000 80 chr6:91032855-91032935 1.0000 80 chr10:91115233-91115313 1.0000 80 chr6:18242808-18242888 1.0000 80 chrX:5225009-5225089 1.0000 80 chr17:76439095-76439175 1.0000 80 chr6:19935582-19935662 1.0000 80 chr19:11874091-11874171 1.0000 80 chr2:102875202-102875282 1.0000 80 chr20:56832034-56832114 1.0000 80 chr5:31362428-31362508 1.0000 80 chr7:129844607-129844687 1.0000 80 chr17:5317111-5317191 1.0000 80 chr1:116417331-116417411 1.0000 80 chr11:45479435-45479515 1.0000 80 chr17:56991451-56991531 1.0000 80 chr15:39689359-39689439 1.0000 80 chr12:76116598-76116678 1.0000 80 chr15:28177905-28177985 1.0000 80 chr10:102647687-10264776 1.0000 80 chr20:3646642-3646722 1.0000 80 chr1:201521171-201521251 1.0000 80 chr2:11262767-11262847 1.0000 80 chr1:201524310-201524390 1.0000 80 chr5:16736501-16736581 1.0000 80 chr16:55410646-55410726 1.0000 80 chr7:91481810-91481890 1.0000 80 chrX:64821698-64821778 1.0000 80 chr15:59461816-59461896 1.0000 80 chr7:123262959-123263039 1.0000 80 chr8:90809101-90809181 1.0000 80 chr7:123633141-123633221 1.0000 80 chr1:53605659-53605739 1.0000 80 chr12:49412886-49412966 1.0000 80 chr12:65955728-65955808 1.0000 80 chr2:167267494-167267574 1.0000 80 chr9:33703571-33703651 1.0000 80 chr15:60314141-60314221 1.0000 80 chr2:68851111-68851191 1.0000 80 chr1:174965713-174965793 1.0000 80 chr15:81062327-81062407 1.0000 80 chr10:21379613-21379693 1.0000 80 chr11:35358778-35358858 1.0000 80 chr3:45147756-45147836 1.0000 80 chr11:72447922-72448002 1.0000 80 chr6:43538812-43538892 1.0000 80 chr4:38939014-38939094 1.0000 80 chr8:20134419-20134499 1.0000 80 chr3:125919525-125919605 1.0000 80 chr22:22378243-22378323 1.0000 80 chr6:88451869-88451949 1.0000 80 chr1:100812724-100812804 1.0000 80 chr7:13889197-13889277 1.0000 80 chr5:87547378-87547458 1.0000 80 chr12:56731714-56731794 1.0000 80 chr7:102632197-102632277 1.0000 80 chr5:175967582-175967662 1.0000 80 chr6:69345088-69345168 1.0000 80 chr2:152899223-152899303 1.0000 80 chr8:29474728-29474808 1.0000 80 chr7:29659626-29659706 1.0000 80 chr5:36703503-36703583 1.0000 80 chr19:15408455-15408535 1.0000 80 chr12:55273061-55273141 1.0000 80 chr8:28982913-28982993 1.0000 80 chr1:89636334-89636414 1.0000 80 chr2:12697967-12698047 1.0000 80 chr7:106239251-106239331 1.0000 80 chrX:15901565-15901645 1.0000 80 chr8:10669939-10670019 1.0000 80 chr18:20807532-20807612 1.0000 80 chr18:34803136-34803216 1.0000 80 chr2:171201424-171201504 1.0000 80 chr4:116926788-116926868 1.0000 80 chr10:125701743-12570182 1.0000 80 chr17:76815121-76815201 1.0000 80 chr7:100795415-100795495 1.0000 80 chr6:150614845-150614925 1.0000 80 chr2:199079004-199079084 1.0000 80 chr17:46438315-46438395 1.0000 80 chr16:50491967-50492047 1.0000 80 chr1:207536685-207536765 1.0000 80 chr16:15581929-15582009 1.0000 80 chr1:221949846-221949926 1.0000 80 chr12:132091145-13209122 1.0000 80 chr13:27704482-27704562 1.0000 80 chr22:22062128-22062208 1.0000 80 chr10:21368155-21368235 1.0000 80 chr16:4501125-4501205 1.0000 80 chr12:50124558-50124638 1.0000 80 chr2:109883619-109883699 1.0000 80 chr18:20840241-20840321 1.0000 80 chr1:94480636-94480716 1.0000 80 chr11:76268669-76268749 1.0000 80 chr17:76297580-76297660 1.0000 80 chr9:110438226-110438306 1.0000 80 chr8:125461725-125461805 1.0000 80 chr15:100526605-10052668 1.0000 80 chr19:8905658-8905738 1.0000 80 chr14:102928013-10292809 1.0000 80 chr1:40525675-40525755 1.0000 80 chr6:27204959-27205039 1.0000 80 chr15:29965602-29965682 1.0000 80 chr4:15523152-15523232 1.0000 80 chr19:39175236-39175316 1.0000 80 chr3:32745068-32745148 1.0000 80 chr1:221871450-221871530 1.0000 80 chr1:204553986-204554066 1.0000 80 chr1:158985308-158985388 1.0000 80 chr7:24818339-24818419 1.0000 80 chr1:150587961-150588041 1.0000 80 chr4:154458955-154459035 1.0000 80 chr1:204141141-204141221 1.0000 80 chr13:29132813-29132893 1.0000 80 chr2:27979910-27979990 1.0000 80 chr15:89545314-89545394 1.0000 80 chr8:142402085-142402165 1.0000 80 chr5:6408953-6409033 1.0000 80 chr1:40367547-40367627 1.0000 80 chr18:9321086-9321166 1.0000 80 chr1:119506470-119506550 1.0000 80 chr8:125971501-125971581 1.0000 80 chr20:9006489-9006569 1.0000 80 chr17:41430110-41430190 1.0000 80 chr14:53746035-53746115 1.0000 80 chr17:47154389-47154469 1.0000 80 chr17:40175858-40175938 1.0000 80 chr21:30164069-30164149 1.0000 80 chr1:160520622-160520702 1.0000 80 chr2:69033949-69034029 1.0000 80 chr3:39326243-39326323 1.0000 80 chr4:57567013-57567093 1.0000 80 chrX:67682137-67682217 1.0000 80 chr6:20203935-20204015 1.0000 80 chr10:15669710-15669790 1.0000 80 chr19:3568849-3568929 1.0000 80 chr12:31887129-31887209 1.0000 80 chr11:221054-221134 1.0000 80 chr9:115990529-115990609 1.0000 80 chr1:227258516-227258596 1.0000 80 chr2:152528976-152529056 1.0000 80 chr7:66313593-66313673 1.0000 80 chr14:93042218-93042298 1.0000 80 chr15:68193177-68193257 1.0000 80 chr7:16532524-16532604 1.0000 80 chr16:77773557-77773637 1.0000 80 chr6:31364690-31364770 1.0000 80 chr4:80773532-80773612 1.0000 80 chr5:169734843-169734923 1.0000 80 chr17:57585705-57585785 1.0000 80 chr6:14077543-14077623 1.0000 80 chr20:343120-343200 1.0000 80 chr15:55694100-55694180 1.0000 80 chr1:234762296-234762376 1.0000 80 chr12:127437993-12743807 1.0000 80 chr4:184256760-184256840 1.0000 80 chr12:127388129-12738820 1.0000 80 chr1:235116681-235116761 1.0000 80 chr13:108930301-10893038 1.0000 80 chr1:147143972-147144052 1.0000 80 chr1:55359153-55359233 1.0000 80 chr15:35286197-35286277 1.0000 80 chr1:25281931-25282011 1.0000 80 chr5:127127290-127127370 1.0000 80 chr19:55978735-55978815 1.0000 80 chr16:58467685-58467765 1.0000 80 chr7:102629248-102629328 1.0000 80 chr8:94886441-94886521 1.0000 80 chr9:139098741-139098821 1.0000 80 chr5:5605505-5605585 1.0000 80 chr1:197908471-197908551 1.0000 80 chr16:17684955-17685035 1.0000 80 chr3:32090136-32090216 1.0000 80 chr17:6851231-6851311 1.0000 80 chr3:186759654-186759734 1.0000 80 chr8:125829796-125829876 1.0000 80 chr11:68034846-68034926 1.0000 80 chr6:136726728-136726808 1.0000 80 chr20:46768466-46768546 1.0000 80 chr5:173205417-173205497 1.0000 80 chr7:150938569-150938649 1.0000 80 chr3:193308472-193308552 1.0000 80 chr3:195073830-195073910 1.0000 80 chr1:222135826-222135906 1.0000 80 chr2:162239393-162239473 1.0000 80 chr15:58242789-58242869 1.0000 80 chr3:146272399-146272479 1.0000 80 chr12:31771241-31771321 1.0000 80 chr22:22378443-22378523 1.0000 80 chr1:112861808-112861888 1.0000 80 chr6:31693828-31693908 1.0000 80 chr22:19668927-19669007 1.0000 80 chr1:18748653-18748733 1.0000 80 chr6:147770890-147770970 1.0000 80 chr3:39363530-39363610 1.0000 80 chr4:36759748-36759828 1.0000 80 chr1:247531151-247531231 1.0000 80 chr5:150142776-150142856 1.0000 80 chr2:69059535-69059615 1.0000 80 chr1:247538122-247538202 1.0000 80 chr1:181143038-181143118 1.0000 80 chr17:3907941-3908021 1.0000 80 chr17:77007687-77007767 1.0000 80 chr5:102393011-102393091 1.0000 80 chr3:138129244-138129324 1.0000 80 chr2:205219398-205219478 1.0000 80 chr9:101614444-101614524 1.0000 80 chr10:63415319-63415399 1.0000 80 chr3:195436729-195436809 1.0000 80 chr11:13299097-13299177 1.0000 80 chr16:12704956-12705036 1.0000 80 chr4:100656044-100656124 1.0000 80 chr3:45100061-45100141 1.0000 80 chr1:206753366-206753446 1.0000 80 chr6:138115937-138116017 1.0000 80 chr1:223079690-223079770 1.0000 80 chr1:236731789-236731869 1.0000 80 chr12:132090112-13209019 1.0000 80 chr1:201596109-201596189 1.0000 80 chrX:3619582-3619662 1.0000 80 chr20:39577462-39577542 1.0000 80 chr16:87421694-87421774 1.0000 80 chr19:11071596-11071676 1.0000 80 ******************************************************************************** ******************************************************************************** COMMAND LINE SUMMARY ******************************************************************************** This information can also be useful in the event you wish to report a problem with the MEME software. command: meme -oc ../result/final_prediction/K562/inference_raw/MEME/RankLinear0.6_40_ZNF175/ -dna -nmotifs 5 -w 8 -maxsize 250000 -nostatus ../result/final_prediction/K562/fasta/RankLinear0.6_40/ZNF175.fasta model: mod= zoops nmotifs= 5 evt= inf objective function: em= E-value of product of p-values starts= E-value of product of p-values strands: + width: minw= 8 maxw= 8 nsites: minsites= 2 maxsites= 250 wnsites= 0.8 theta: spmap= uni spfuzz= 0.5 em: prior= dirichlet b= 0.01 maxiter= 50 distance= 1e-05 trim: wg= 11 ws= 1 endgaps= yes data: n= 20000 N= 250 sample: seed= 0 hsfrac= 0 searchsize= 20000 norand= no csites= 1000 Letter frequencies in dataset: A 0.272 C 0.225 G 0.237 T 0.265 Background letter frequencies (from file dataset with add-one prior applied): A 0.272 C 0.225 G 0.237 T 0.265 Background model order: 0 ******************************************************************************** ******************************************************************************** MOTIF AGATGGAG MEME-1 width = 8 sites = 55 llr = 482 E-value = 5.1e-034 ******************************************************************************** -------------------------------------------------------------------------------- Motif AGATGGAG MEME-1 Description -------------------------------------------------------------------------------- Simplified A 93a::19: pos.-specific C 1::::::: probability G 17::a91a matrix T :::a::1: bits 2.1 * 1.9 * * 1.7 *** * 1.5 **** * Relative 1.3 * ****** Entropy 1.1 ******** (12.6 bits) 0.9 ******** 0.6 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel AGATGGAG consensus A sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AGATGGAG MEME-1 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr20:39577462-39577542 27 1.68e-05 ccgctattca agatggag ttgctctggt chr12:132090112-13209019 37 1.68e-05 cccctgttca agatggag tcattctggt chr4:100656044-100656124 5 1.68e-05 ttta agatggag ttagtctggt chr9:101614444-101614524 2 1.68e-05 a agatggag ttactgtggt chr2:205219398-205219478 17 1.68e-05 gtgaaatgta agatggag tctttttcta chr6:147770890-147770970 29 1.68e-05 cccccattca agatggag acattctggt chr3:193308472-193308552 37 1.68e-05 gtcagaagca agatggag tcaactatgt chr20:46768466-46768546 16 1.68e-05 cccctattca agatggag ttgctctggt chr8:94886441-94886521 2 1.68e-05 a agatggag tcactctagt chr15:35286197-35286277 30 1.68e-05 tttgaaagta agatggag tcgattaggt chr13:108930301-10893038 39 1.68e-05 ctcctatcca agatggag gttctctggt chr12:127388129-12738820 7 1.68e-05 tgttta agatggag ttgctcaggt chr16:77773557-77773637 26 1.68e-05 cccctattca agatggag ttgctctggt chr15:68193177-68193257 22 1.68e-05 gcactattca agatggag ttgctctggt chr12:31887129-31887209 29 1.68e-05 gttagaagca agatggag tcggttaagt chr17:47154389-47154469 66 1.68e-05 tctgacaGTT AGATGGAG GAAAGGA chr15:89545314-89545394 28 1.68e-05 tctttttcta agatggag ttagttgggt chr4:154458955-154459035 2 1.68e-05 a agatggag ttgctctggt chr8:125461725-125461805 12 1.68e-05 cctttattca agatggag tcactctggt chr9:110438226-110438306 23 1.68e-05 cccctattca agatggag tcactctggt chrX:15901565-15901645 10 1.68e-05 ccctattca agatggag ttgctctggt chr2:12697967-12698047 19 1.68e-05 cccctactca agatggag tcactctggt chr8:28982913-28982993 16 1.68e-05 gttgtggaca agatggag aaacgtgcga chr7:29659626-29659706 23 1.68e-05 cccttattca agatggag ttgctgtggt chr15:81062327-81062407 39 1.68e-05 cccctgttca agatggag tcgctgtggt chr7:123633141-123633221 40 1.68e-05 gccctattca agatggag tcactctggt chr5:31362428-31362508 1 1.68e-05 . agatggag tcactctggt chr4:36759748-36759828 23 3.61e-05 gcccctatca aaatggag ttgccatggt chr12:31771241-31771321 18 3.61e-05 ccaaaaatca aaatggag tcacccatgc chr17:6851231-6851311 18 3.61e-05 gaccaaacca aaatggag tcactcatgc chr16:58467685-58467765 3 3.61e-05 ca aaatggag ttgctcttgt chr17:41430110-41430190 13 3.61e-05 ccctccctca aaatggag tcgctttggt chr1:89636334-89636414 55 3.61e-05 aaccctaaca aaatggag tcaggagttc chr20:3646642-3646722 9 5.08e-05 cctattca ggatggag ttgctctggt chr10:102647687-10264776 26 6.47e-05 ttagcatccg cgatggag tcgctcttgt chr6:31364690-31364770 56 9.87e-05 gttggaagca agatgggg tcagttaggt chr14:93042218-93042298 36 9.87e-05 cccctattca agatgggg gtcactctgg chr1:116417331-116417411 40 9.87e-05 gactggttgg agatgaag atgcttctgg chr1:160520622-160520702 65 1.15e-04 CCTGTCATGG AGATGGTG GCACAGGG chr16:15581929-15582009 24 1.15e-04 cccctattca agatggtg ttgttctggt chr15:60314141-60314221 29 1.15e-04 cccctactca agatggtg tcgctccagt chr22:22378443-22378523 2 1.32e-04 a gaatggag aggcctggga chr17:57585705-57585785 47 1.32e-04 gaccaaacca gaatggag tcactcatgc chr6:20203935-20204015 38 1.32e-04 gaccaaacca gaatggag tcactgatgc chr1:25281931-25282011 4 1.48e-04 cca caatggag gtggtgatgc chr7:66313593-66313673 7 1.48e-04 TTTACA CAATGGAG TTGCTGTTTC chr5:102393011-102393091 59 2.01e-04 gggctgggta aaatgaag ctgagaacta chr4:80773532-80773612 11 2.01e-04 CAAGGCTGTG AAATGGGG CTATGCTTGG chr4:57567013-57567093 65 2.01e-04 gggctgggta aaatgaag atgaaacc chr22:22378243-22378323 72 2.01e-04 GTGGCTGCAG AGCTGGAG G chr7:123262959-123263039 6 2.01e-04 CTCCC AAATGAAG TAGGCAAAGT chr3:39326243-39326323 56 2.36e-04 cttcctgccc agatgcag GCAGGGAACA chr15:39689359-39689439 31 2.83e-04 CAGAGTAAGA AGATGGAC ATTGCGTCAC chr6:25866424-25866504 45 2.83e-04 gtaagcagga agttggag aacctaacac chr1:9138482-9138562 40 4.16e-04 aggaggcggg aaagggag agaagacttt -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AGATGGAG MEME-1 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr20:39577462-39577542 1.7e-05 26_[+1]_46 chr12:132090112-13209019 1.7e-05 36_[+1]_36 chr4:100656044-100656124 1.7e-05 4_[+1]_68 chr9:101614444-101614524 1.7e-05 1_[+1]_71 chr2:205219398-205219478 1.7e-05 16_[+1]_56 chr6:147770890-147770970 1.7e-05 28_[+1]_44 chr3:193308472-193308552 1.7e-05 36_[+1]_36 chr20:46768466-46768546 1.7e-05 15_[+1]_57 chr8:94886441-94886521 1.7e-05 1_[+1]_71 chr15:35286197-35286277 1.7e-05 29_[+1]_43 chr13:108930301-10893038 1.7e-05 38_[+1]_34 chr12:127388129-12738820 1.7e-05 6_[+1]_66 chr16:77773557-77773637 1.7e-05 25_[+1]_47 chr15:68193177-68193257 1.7e-05 21_[+1]_51 chr12:31887129-31887209 1.7e-05 28_[+1]_44 chr17:47154389-47154469 1.7e-05 65_[+1]_7 chr15:89545314-89545394 1.7e-05 27_[+1]_45 chr4:154458955-154459035 1.7e-05 1_[+1]_71 chr8:125461725-125461805 1.7e-05 11_[+1]_61 chr9:110438226-110438306 1.7e-05 22_[+1]_50 chrX:15901565-15901645 1.7e-05 9_[+1]_63 chr2:12697967-12698047 1.7e-05 18_[+1]_54 chr8:28982913-28982993 1.7e-05 15_[+1]_57 chr7:29659626-29659706 1.7e-05 22_[+1]_50 chr15:81062327-81062407 1.7e-05 38_[+1]_34 chr7:123633141-123633221 1.7e-05 39_[+1]_33 chr5:31362428-31362508 1.7e-05 [+1]_72 chr4:36759748-36759828 3.6e-05 22_[+1]_50 chr12:31771241-31771321 3.6e-05 17_[+1]_55 chr17:6851231-6851311 3.6e-05 17_[+1]_55 chr16:58467685-58467765 3.6e-05 2_[+1]_70 chr17:41430110-41430190 3.6e-05 12_[+1]_60 chr1:89636334-89636414 3.6e-05 54_[+1]_18 chr20:3646642-3646722 5.1e-05 8_[+1]_64 chr10:102647687-10264776 6.5e-05 25_[+1]_47 chr6:31364690-31364770 9.9e-05 55_[+1]_17 chr14:93042218-93042298 9.9e-05 35_[+1]_37 chr1:116417331-116417411 9.9e-05 39_[+1]_33 chr1:160520622-160520702 0.00012 64_[+1]_8 chr16:15581929-15582009 0.00012 23_[+1]_49 chr15:60314141-60314221 0.00012 28_[+1]_44 chr22:22378443-22378523 0.00013 1_[+1]_71 chr17:57585705-57585785 0.00013 46_[+1]_26 chr6:20203935-20204015 0.00013 37_[+1]_35 chr1:25281931-25282011 0.00015 3_[+1]_69 chr7:66313593-66313673 0.00015 6_[+1]_66 chr5:102393011-102393091 0.0002 58_[+1]_14 chr4:80773532-80773612 0.0002 10_[+1]_62 chr4:57567013-57567093 0.0002 64_[+1]_8 chr22:22378243-22378323 0.0002 71_[+1]_1 chr7:123262959-123263039 0.0002 5_[+1]_67 chr3:39326243-39326323 0.00024 55_[+1]_17 chr15:39689359-39689439 0.00028 30_[+1]_42 chr6:25866424-25866504 0.00028 44_[+1]_28 chr1:9138482-9138562 0.00042 39_[+1]_33 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AGATGGAG MEME-1 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF AGATGGAG width=8 seqs=55 chr20:39577462-39577542 ( 27) AGATGGAG 1 chr12:132090112-13209019 ( 37) AGATGGAG 1 chr4:100656044-100656124 ( 5) AGATGGAG 1 chr9:101614444-101614524 ( 2) AGATGGAG 1 chr2:205219398-205219478 ( 17) AGATGGAG 1 chr6:147770890-147770970 ( 29) AGATGGAG 1 chr3:193308472-193308552 ( 37) AGATGGAG 1 chr20:46768466-46768546 ( 16) AGATGGAG 1 chr8:94886441-94886521 ( 2) AGATGGAG 1 chr15:35286197-35286277 ( 30) AGATGGAG 1 chr13:108930301-10893038 ( 39) AGATGGAG 1 chr12:127388129-12738820 ( 7) AGATGGAG 1 chr16:77773557-77773637 ( 26) AGATGGAG 1 chr15:68193177-68193257 ( 22) AGATGGAG 1 chr12:31887129-31887209 ( 29) AGATGGAG 1 chr17:47154389-47154469 ( 66) AGATGGAG 1 chr15:89545314-89545394 ( 28) AGATGGAG 1 chr4:154458955-154459035 ( 2) AGATGGAG 1 chr8:125461725-125461805 ( 12) AGATGGAG 1 chr9:110438226-110438306 ( 23) AGATGGAG 1 chrX:15901565-15901645 ( 10) AGATGGAG 1 chr2:12697967-12698047 ( 19) AGATGGAG 1 chr8:28982913-28982993 ( 16) AGATGGAG 1 chr7:29659626-29659706 ( 23) AGATGGAG 1 chr15:81062327-81062407 ( 39) AGATGGAG 1 chr7:123633141-123633221 ( 40) AGATGGAG 1 chr5:31362428-31362508 ( 1) AGATGGAG 1 chr4:36759748-36759828 ( 23) AAATGGAG 1 chr12:31771241-31771321 ( 18) AAATGGAG 1 chr17:6851231-6851311 ( 18) AAATGGAG 1 chr16:58467685-58467765 ( 3) AAATGGAG 1 chr17:41430110-41430190 ( 13) AAATGGAG 1 chr1:89636334-89636414 ( 55) AAATGGAG 1 chr20:3646642-3646722 ( 9) GGATGGAG 1 chr10:102647687-10264776 ( 26) CGATGGAG 1 chr6:31364690-31364770 ( 56) AGATGGGG 1 chr14:93042218-93042298 ( 36) AGATGGGG 1 chr1:116417331-116417411 ( 40) AGATGAAG 1 chr1:160520622-160520702 ( 65) AGATGGTG 1 chr16:15581929-15582009 ( 24) AGATGGTG 1 chr15:60314141-60314221 ( 29) AGATGGTG 1 chr22:22378443-22378523 ( 2) GAATGGAG 1 chr17:57585705-57585785 ( 47) GAATGGAG 1 chr6:20203935-20204015 ( 38) GAATGGAG 1 chr1:25281931-25282011 ( 4) CAATGGAG 1 chr7:66313593-66313673 ( 7) CAATGGAG 1 chr5:102393011-102393091 ( 59) AAATGAAG 1 chr4:80773532-80773612 ( 11) AAATGGGG 1 chr4:57567013-57567093 ( 65) AAATGAAG 1 chr22:22378243-22378323 ( 72) AGCTGGAG 1 chr7:123262959-123263039 ( 6) AAATGAAG 1 chr3:39326243-39326323 ( 56) AGATGCAG 1 chr15:39689359-39689439 ( 31) AGATGGAC 1 chr6:25866424-25866504 ( 45) AGTTGGAG 1 chr1:9138482-9138562 ( 40) AAAGGGAG 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AGATGGAG MEME-1 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 8.95894 E= 5.1e-034 168 -205 -170 -1243 10 -1243 158 -1243 182 -363 -1243 -386 -1243 -1243 -370 189 -1243 -1243 208 -1243 -190 -363 194 -1243 171 -1243 -212 -228 -1243 -363 205 -1243 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AGATGGAG MEME-1 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 55 E= 5.1e-034 0.872727 0.054545 0.072727 0.000000 0.290909 0.000000 0.709091 0.000000 0.963636 0.018182 0.000000 0.018182 0.000000 0.000000 0.018182 0.981818 0.000000 0.000000 1.000000 0.000000 0.072727 0.018182 0.909091 0.000000 0.890909 0.000000 0.054545 0.054545 0.000000 0.018182 0.981818 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AGATGGAG MEME-1 regular expression -------------------------------------------------------------------------------- A[GA]ATGGAG -------------------------------------------------------------------------------- Time 4.99 secs. ******************************************************************************** ******************************************************************************** MOTIF TCTGGTTC MEME-2 width = 8 sites = 35 llr = 336 E-value = 8.1e-023 ******************************************************************************** -------------------------------------------------------------------------------- Motif TCTGGTTC MEME-2 Description -------------------------------------------------------------------------------- Simplified A ::1::::: pos.-specific C :9:::1:9 probability G :1:a9::: matrix T a:9:19a1 bits 2.1 * 1.9 * * 1.7 ** ** ** 1.5 ******** Relative 1.3 ******** Entropy 1.1 ******** (13.8 bits) 0.9 ******** 0.6 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel TCTGGTTC consensus sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCTGGTTC MEME-2 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr20:39577462-39577542 39 1.40e-05 atggagttgc tctggttc aaatgcctcc chr12:132090112-13209019 49 1.40e-05 atggagtcat tctggttc aaatgcctct chr4:100656044-100656124 17 1.40e-05 atggagttag tctggttc acacacctct chr6:147770890-147770970 41 1.40e-05 atggagacat tctggttc aaatgcctct chr20:46768466-46768546 28 1.40e-05 atggagttgc tctggttc aagtgcctct chr5:5605505-5605585 22 1.40e-05 TTGTGCCACT TCTGGTTC CTGCTCCTTG chr13:108930301-10893038 51 1.40e-05 atggaggttc tctggttc acctgcctct chr16:77773557-77773637 38 1.40e-05 atggagttgc tctggttc aaacgcctct chr15:68193177-68193257 34 1.40e-05 atggagttgc tctggttc cagtgcttct chr14:93042218-93042298 49 1.40e-05 tgggggtcac tctggttc agacgGACAC chr17:47154389-47154469 41 1.40e-05 atggagtcgc tctggttc aaacaactct chr4:154458955-154459035 14 1.40e-05 atggagttgc tctggttc aaaagcctct chr9:110438226-110438306 35 1.40e-05 atggagtcac tctggttc aaacgcctct chr16:15581929-15582009 36 1.40e-05 atggtgttgt tctggttc aaacgcttct chr2:12697967-12698047 31 1.40e-05 atggagtcac tctggttc aaacgcctga chr22:22378243-22378323 36 1.40e-05 atggagtcac tctggttc taacacctct chr7:123633141-123633221 52 1.40e-05 atggagtcac tctggttc caatgcttct chr20:3646642-3646722 21 1.40e-05 atggagttgc tctggttc acaggcctct chr5:31362428-31362508 13 1.40e-05 atggagtcac tctggttc aaacacctct chr1:9138482-9138562 9 1.40e-05 ggagtcgc tctggttc caatgcctct chr13:29132813-29132893 52 2.59e-05 ATGGCCACCG TCTGGCTC CTTGCCCCAG chr16:55410646-55410726 10 2.59e-05 GTCACAGAC TCTGGCTC ATTGTGCCTG chr1:116417331-116417411 4 2.59e-05 cgc tctggctc aagcacctct chrX:64821698-64821778 4 4.16e-05 CTA TCTGTTTC CTCTGATTCA chr8:49944967-49945047 43 4.16e-05 acataaagtc tctgtttc ttagcttgct chr7:64766111-64766191 72 4.16e-05 GCTCTGCTTG TCTGTTTC T chr8:125461725-125461805 24 5.81e-05 atggagtcac tctggttt ggactcctct chrX:15901565-15901645 22 5.81e-05 atggagttgc tctggttt gattgcctct chr2:11262767-11262847 2 5.81e-05 c tctggttt acatgcctct chr3:193308472-193308552 54 7.25e-05 gtcaactatg tcaggttc ctcttgtcat chr12:127388129-12738820 19 7.25e-05 atggagttgc tcaggttc aaatgtcttt chr15:29965602-29965682 5 8.73e-05 tcgc tgtggttc aaacacctct chr7:29659626-29659706 35 8.73e-05 atggagttgc tgtggttc aaacacctct chr7:91481810-91481890 28 1.12e-04 tcaagggtga gctggttc ttattcttaa chr1:236673375-236673455 10 1.12e-04 catgtttac tctggtcc attgtagcct -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCTGGTTC MEME-2 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr20:39577462-39577542 1.4e-05 38_[+2]_34 chr12:132090112-13209019 1.4e-05 48_[+2]_24 chr4:100656044-100656124 1.4e-05 16_[+2]_56 chr6:147770890-147770970 1.4e-05 40_[+2]_32 chr20:46768466-46768546 1.4e-05 27_[+2]_45 chr5:5605505-5605585 1.4e-05 21_[+2]_51 chr13:108930301-10893038 1.4e-05 50_[+2]_22 chr16:77773557-77773637 1.4e-05 37_[+2]_35 chr15:68193177-68193257 1.4e-05 33_[+2]_39 chr14:93042218-93042298 1.4e-05 48_[+2]_24 chr17:47154389-47154469 1.4e-05 40_[+2]_32 chr4:154458955-154459035 1.4e-05 13_[+2]_59 chr9:110438226-110438306 1.4e-05 34_[+2]_38 chr16:15581929-15582009 1.4e-05 35_[+2]_37 chr2:12697967-12698047 1.4e-05 30_[+2]_42 chr22:22378243-22378323 1.4e-05 35_[+2]_37 chr7:123633141-123633221 1.4e-05 51_[+2]_21 chr20:3646642-3646722 1.4e-05 20_[+2]_52 chr5:31362428-31362508 1.4e-05 12_[+2]_60 chr1:9138482-9138562 1.4e-05 8_[+2]_64 chr13:29132813-29132893 2.6e-05 51_[+2]_21 chr16:55410646-55410726 2.6e-05 9_[+2]_63 chr1:116417331-116417411 2.6e-05 3_[+2]_69 chrX:64821698-64821778 4.2e-05 3_[+2]_69 chr8:49944967-49945047 4.2e-05 42_[+2]_30 chr7:64766111-64766191 4.2e-05 71_[+2]_1 chr8:125461725-125461805 5.8e-05 23_[+2]_49 chrX:15901565-15901645 5.8e-05 21_[+2]_51 chr2:11262767-11262847 5.8e-05 1_[+2]_71 chr3:193308472-193308552 7.3e-05 53_[+2]_19 chr12:127388129-12738820 7.3e-05 18_[+2]_54 chr15:29965602-29965682 8.7e-05 4_[+2]_68 chr7:29659626-29659706 8.7e-05 34_[+2]_38 chr7:91481810-91481890 0.00011 27_[+2]_45 chr1:236673375-236673455 0.00011 9_[+2]_63 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCTGGTTC MEME-2 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF TCTGGTTC width=8 seqs=35 chr20:39577462-39577542 ( 39) TCTGGTTC 1 chr12:132090112-13209019 ( 49) TCTGGTTC 1 chr4:100656044-100656124 ( 17) TCTGGTTC 1 chr6:147770890-147770970 ( 41) TCTGGTTC 1 chr20:46768466-46768546 ( 28) TCTGGTTC 1 chr5:5605505-5605585 ( 22) TCTGGTTC 1 chr13:108930301-10893038 ( 51) TCTGGTTC 1 chr16:77773557-77773637 ( 38) TCTGGTTC 1 chr15:68193177-68193257 ( 34) TCTGGTTC 1 chr14:93042218-93042298 ( 49) TCTGGTTC 1 chr17:47154389-47154469 ( 41) TCTGGTTC 1 chr4:154458955-154459035 ( 14) TCTGGTTC 1 chr9:110438226-110438306 ( 35) TCTGGTTC 1 chr16:15581929-15582009 ( 36) TCTGGTTC 1 chr2:12697967-12698047 ( 31) TCTGGTTC 1 chr22:22378243-22378323 ( 36) TCTGGTTC 1 chr7:123633141-123633221 ( 52) TCTGGTTC 1 chr20:3646642-3646722 ( 21) TCTGGTTC 1 chr5:31362428-31362508 ( 13) TCTGGTTC 1 chr1:9138482-9138562 ( 9) TCTGGTTC 1 chr13:29132813-29132893 ( 52) TCTGGCTC 1 chr16:55410646-55410726 ( 10) TCTGGCTC 1 chr1:116417331-116417411 ( 4) TCTGGCTC 1 chrX:64821698-64821778 ( 4) TCTGTTTC 1 chr8:49944967-49945047 ( 43) TCTGTTTC 1 chr7:64766111-64766191 ( 72) TCTGTTTC 1 chr8:125461725-125461805 ( 24) TCTGGTTT 1 chrX:15901565-15901645 ( 22) TCTGGTTT 1 chr2:11262767-11262847 ( 2) TCTGGTTT 1 chr3:193308472-193308552 ( 54) TCAGGTTC 1 chr12:127388129-12738820 ( 19) TCAGGTTC 1 chr15:29965602-29965682 ( 5) TGTGGTTC 1 chr7:29659626-29659706 ( 35) TGTGGTTC 1 chr7:91481810-91481890 ( 28) GCTGGTTC 1 chr1:236673375-236673455 ( 10) TCTGGTCC 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCTGGTTC MEME-2 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 9.12623 E= 8.1e-023 -1177 -1177 -305 187 -1177 206 -205 -1177 -225 -1177 -1177 183 -1177 -1177 208 -1177 -1177 -1177 195 -163 -1177 -139 -1177 179 -1177 -298 -1177 187 -1177 202 -1177 -163 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCTGGTTC MEME-2 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 35 E= 8.1e-023 0.000000 0.000000 0.028571 0.971429 0.000000 0.942857 0.057143 0.000000 0.057143 0.000000 0.000000 0.942857 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.914286 0.085714 0.000000 0.085714 0.000000 0.914286 0.000000 0.028571 0.000000 0.971429 0.000000 0.914286 0.000000 0.085714 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCTGGTTC MEME-2 regular expression -------------------------------------------------------------------------------- TCTGGTTC -------------------------------------------------------------------------------- Time 8.74 secs. ******************************************************************************** ******************************************************************************** MOTIF CCTCTGAC MEME-3 width = 8 sites = 32 llr = 311 E-value = 1.8e-020 ******************************************************************************** -------------------------------------------------------------------------------- Motif CCTCTGAC MEME-3 Description -------------------------------------------------------------------------------- Simplified A ::::::a1 pos.-specific C a9:a:::8 probability G :::::a:1 matrix T :1a:a::: bits 2.1 * 1.9 * * * 1.7 * ***** 1.5 ******* Relative 1.3 ******** Entropy 1.1 ******** (14.0 bits) 0.9 ******** 0.6 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel CCTCTGAC consensus sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCTCTGAC MEME-3 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr12:132090112-13209019 62 1.16e-05 ggttcaaatg cctctgac aCTTCCCTCA chr4:100656044-100656124 30 1.16e-05 ggttcacaca cctctgac aGTGTTCTTC chr4:36759748-36759828 48 1.16e-05 ggttcaaaca cctctgac ataatgaatc chr6:147770890-147770970 54 1.16e-05 ggttcaaatg cctctgac aCTATGCTGT chr20:46768466-46768546 41 1.16e-05 ggttcaagtg cctctgac aatcatgggg chr13:108930301-10893038 64 1.16e-05 ggttcacctg cctctgac aTCATTATA chr16:77773557-77773637 51 1.16e-05 ggttcaaacg cctctgac aACACTTGGC chr1:204141141-204141221 68 1.16e-05 ctccattttg cctctgac cccca chr4:154458955-154459035 27 1.16e-05 ggttcaaaag cctctgac aAACCTGTAG chr15:29965602-29965682 18 1.16e-05 ggttcaaaca cctctgac aaaatcacgg chr8:125461725-125461805 37 1.16e-05 ggtttggact cctctgac aGCGGGAGTG chrX:15901565-15901645 35 1.16e-05 ggtttgattg cctctgac aGTATCATGA chr22:22378243-22378323 49 1.16e-05 ggttctaaca cctctgac TTAGGGTGGC chr15:60314141-60314221 54 1.16e-05 agttcaaatg cctctgac aCAACCAATT chr2:11262767-11262847 15 1.16e-05 ggtttacatg cctctgac aTGAGCATGT chr20:3646642-3646722 34 1.16e-05 ggttcacagg cctctgac aCATCCTCTT chr1:116417331-116417411 17 1.16e-05 ggctcaagca cctctgac atcatgactg chr5:31362428-31362508 26 1.16e-05 ggttcaaaca cctctgac aCTTCCACTC chr1:9138482-9138562 22 1.16e-05 ggttccaatg cctctgac aggaggcggg chr15:100526605-10052668 62 2.38e-05 ATTCGAAAGG CCTCTGAG GCACTGCTAT chr9:110438226-110438306 48 2.38e-05 ggttcaaacg cctctgag ataagggcct chr16:22365055-22365135 41 2.38e-05 ttcaaagcca cctctgag aatgactcat chr2:109883619-109883699 56 3.78e-05 AATCTCCCTT CCTCTGAA TAGGAAGTGC chr7:29659626-29659706 48 3.78e-05 ggttcaaaca cctctgaA AATGGGATCT chr16:15581929-15582009 49 5.15e-05 ggttcaaacg cttctgac agtatggtct chr7:123633141-123633221 65 5.15e-05 ggttccaatg cttctgac aGCAGTAG chr9:101614444-101614524 27 6.14e-05 ggtttgaaca cccctgac actggcccac chr8:94886441-94886521 27 9.29e-05 agttcagatg cctctggc ataactaccc chr17:41430110-41430190 38 9.29e-05 ggttcaaatg cctcggac atatctcccc chr3:45147756-45147836 12 9.29e-05 CTGGCTGGTG CCTCTCAC AGCTTTCTCC chr6:150614845-150614925 4 1.19e-04 TGC CATCTGAC TCTCTTTCTG chr15:81062327-81062407 63 1.19e-04 tggtttgaat gctctgac actcctgagg -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCTCTGAC MEME-3 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr12:132090112-13209019 1.2e-05 61_[+3]_11 chr4:100656044-100656124 1.2e-05 29_[+3]_43 chr4:36759748-36759828 1.2e-05 47_[+3]_25 chr6:147770890-147770970 1.2e-05 53_[+3]_19 chr20:46768466-46768546 1.2e-05 40_[+3]_32 chr13:108930301-10893038 1.2e-05 63_[+3]_9 chr16:77773557-77773637 1.2e-05 50_[+3]_22 chr1:204141141-204141221 1.2e-05 67_[+3]_5 chr4:154458955-154459035 1.2e-05 26_[+3]_46 chr15:29965602-29965682 1.2e-05 17_[+3]_55 chr8:125461725-125461805 1.2e-05 36_[+3]_36 chrX:15901565-15901645 1.2e-05 34_[+3]_38 chr22:22378243-22378323 1.2e-05 48_[+3]_24 chr15:60314141-60314221 1.2e-05 53_[+3]_19 chr2:11262767-11262847 1.2e-05 14_[+3]_58 chr20:3646642-3646722 1.2e-05 33_[+3]_39 chr1:116417331-116417411 1.2e-05 16_[+3]_56 chr5:31362428-31362508 1.2e-05 25_[+3]_47 chr1:9138482-9138562 1.2e-05 21_[+3]_51 chr15:100526605-10052668 2.4e-05 61_[+3]_11 chr9:110438226-110438306 2.4e-05 47_[+3]_25 chr16:22365055-22365135 2.4e-05 40_[+3]_32 chr2:109883619-109883699 3.8e-05 55_[+3]_17 chr7:29659626-29659706 3.8e-05 47_[+3]_25 chr16:15581929-15582009 5.2e-05 48_[+3]_24 chr7:123633141-123633221 5.2e-05 64_[+3]_8 chr9:101614444-101614524 6.1e-05 26_[+3]_46 chr8:94886441-94886521 9.3e-05 26_[+3]_46 chr17:41430110-41430190 9.3e-05 37_[+3]_35 chr3:45147756-45147836 9.3e-05 11_[+3]_61 chr6:150614845-150614925 0.00012 3_[+3]_69 chr15:81062327-81062407 0.00012 62_[+3]_10 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCTCTGAC MEME-3 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF CCTCTGAC width=8 seqs=32 chr12:132090112-13209019 ( 62) CCTCTGAC 1 chr4:100656044-100656124 ( 30) CCTCTGAC 1 chr4:36759748-36759828 ( 48) CCTCTGAC 1 chr6:147770890-147770970 ( 54) CCTCTGAC 1 chr20:46768466-46768546 ( 41) CCTCTGAC 1 chr13:108930301-10893038 ( 64) CCTCTGAC 1 chr16:77773557-77773637 ( 51) CCTCTGAC 1 chr1:204141141-204141221 ( 68) CCTCTGAC 1 chr4:154458955-154459035 ( 27) CCTCTGAC 1 chr15:29965602-29965682 ( 18) CCTCTGAC 1 chr8:125461725-125461805 ( 37) CCTCTGAC 1 chrX:15901565-15901645 ( 35) CCTCTGAC 1 chr22:22378243-22378323 ( 49) CCTCTGAC 1 chr15:60314141-60314221 ( 54) CCTCTGAC 1 chr2:11262767-11262847 ( 15) CCTCTGAC 1 chr20:3646642-3646722 ( 34) CCTCTGAC 1 chr1:116417331-116417411 ( 17) CCTCTGAC 1 chr5:31362428-31362508 ( 26) CCTCTGAC 1 chr1:9138482-9138562 ( 22) CCTCTGAC 1 chr15:100526605-10052668 ( 62) CCTCTGAG 1 chr9:110438226-110438306 ( 48) CCTCTGAG 1 chr16:22365055-22365135 ( 41) CCTCTGAG 1 chr2:109883619-109883699 ( 56) CCTCTGAA 1 chr7:29659626-29659706 ( 48) CCTCTGAA 1 chr16:15581929-15582009 ( 49) CTTCTGAC 1 chr7:123633141-123633221 ( 65) CTTCTGAC 1 chr9:101614444-101614524 ( 27) CCCCTGAC 1 chr8:94886441-94886521 ( 27) CCTCTGGC 1 chr17:41430110-41430190 ( 38) CCTCGGAC 1 chr3:45147756-45147836 ( 12) CCTCTCAC 1 chr6:150614845-150614925 ( 4) CATCTGAC 1 chr15:81062327-81062407 ( 63) GCTCTGAC 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCTCTGAC MEME-3 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 9.89106 E= 1.8e-020 -1164 210 -292 -1164 -312 201 -1164 -208 -1164 -285 -1164 187 -1164 215 -1164 -1164 -1164 -1164 -292 187 -1164 -285 203 -1164 183 -1164 -292 -1164 -212 190 -134 -1164 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCTCTGAC MEME-3 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 32 E= 1.8e-020 0.000000 0.968750 0.031250 0.000000 0.031250 0.906250 0.000000 0.062500 0.000000 0.031250 0.000000 0.968750 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.031250 0.968750 0.000000 0.031250 0.968750 0.000000 0.968750 0.000000 0.031250 0.000000 0.062500 0.843750 0.093750 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCTCTGAC MEME-3 regular expression -------------------------------------------------------------------------------- CCTCTGAC -------------------------------------------------------------------------------- Time 12.42 secs. ******************************************************************************** ******************************************************************************** MOTIF CCATCTTG MEME-4 width = 8 sites = 36 llr = 343 E-value = 1.3e-022 ******************************************************************************** -------------------------------------------------------------------------------- Motif CCATCTTG MEME-4 Description -------------------------------------------------------------------------------- Simplified A ::a:1::1 pos.-specific C aa::7::: probability G ::::1::9 matrix T :::a1aa1 bits 2.1 ** 1.9 **** 1.7 **** ** 1.5 **** ** Relative 1.3 **** *** Entropy 1.1 **** *** (13.7 bits) 0.9 ******** 0.6 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel CCATCTTG consensus sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCATCTTG MEME-4 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chrX:3619582-3619662 64 1.37e-05 cagagcaact ccatcttg aagaggagc chr5:102393011-102393091 36 1.37e-05 gagagctaca ccatcttg aatgggggct chr17:77007687-77007767 66 1.37e-05 cagagcaaca ccatcttg aataagg chr1:181143038-181143118 63 1.37e-05 cagagtgact ccatcttg aataggggct chr1:18748653-18748733 49 1.37e-05 aagagtgact ccatcttg aatacagggt chr16:17684955-17685035 42 1.37e-05 cagagtgacc ccatcttg aataagggct chr1:147143972-147144052 67 1.37e-05 catagtgact ccatcttg aatagc chr12:127437993-12743807 41 1.37e-05 cagagcaact ccatcttg aataagggct chr6:14077543-14077623 48 1.37e-05 cggagagact ccatcttg aatagggctg chr10:15669710-15669790 68 1.37e-05 cagagcaact ccatcttg aatag chr21:30164069-30164149 36 1.37e-05 cagagtgact ccatcttg aataggggac chr20:9006489-9006569 35 1.37e-05 ctaaccaact ccatcttg cttctaacct chr10:21368155-21368235 64 1.37e-05 AGTAGTACCA CCATCTTG AGATTTTAA chr16:50491967-50492047 37 1.37e-05 cagagcgact ccatcttg aatagaggct chr7:100795415-100795495 56 1.37e-05 aagttcagct ccatcttg aaactaacaa chr10:125701743-12570182 34 1.37e-05 cacagtgact ccatcttg aacagggact chr8:29474728-29474808 56 1.37e-05 cagagcaact ccatcttg aatagggact chr2:152899223-152899303 32 1.37e-05 cagagcaact ccatcttg aataggagct chr6:18242808-18242888 63 1.37e-05 tcactagcag ccatcttg gttatcctat chr2:162239393-162239473 70 2.98e-05 CATGGAGTGA CCATTTTG CTG chr1:55359153-55359233 46 2.98e-05 attagtgact ccattttg atgctgacaa chr4:184256760-184256840 38 2.98e-05 TTTTCTGAGA CCATTTTG CAGTGACCAC chr1:204141141-204141221 60 2.98e-05 atgactgact ccattttg cctctgaccc chr8:90809101-90809181 25 2.98e-05 cagagcaact ccattttg aataggggct chr6:136726728-136726808 56 6.16e-05 gcctggcagg ccatattg caagtgggtc chr2:152528976-152529056 20 6.16e-05 ACATCCTGGG CCATCTTT GCAGCTGTGA chrX:67682137-67682217 42 6.16e-05 cagagtgact ccatcttt aataggtgct chr4:57567013-57567093 42 6.16e-05 caaagtgact ccatcttt aataggggct chr3:125919525-125919605 54 6.16e-05 atgagtgact ccatattg gcttggtctg chr1:53605659-53605739 29 6.16e-05 CTACCATTTT CCATATTG TTTATGATTT chr2:171201424-171201504 70 7.60e-05 AGTAGTGTGG CCATGTTG ACA chr8:20134419-20134499 62 7.60e-05 cagagcaact ccatgttg aataggggct chr1:223079690-223079770 47 9.16e-05 cagagcaact ccatctta aataggggct chr9:33703571-33703651 72 9.16e-05 cagagcaact ccatctta a chr22:22378443-22378523 47 1.15e-04 gttgctcatg ccatcctg gtgggaagat chr14:102928013-10292809 72 1.15e-04 TGCGGCTCCA CCATCTCG G -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCATCTTG MEME-4 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chrX:3619582-3619662 1.4e-05 63_[+4]_9 chr5:102393011-102393091 1.4e-05 35_[+4]_37 chr17:77007687-77007767 1.4e-05 65_[+4]_7 chr1:181143038-181143118 1.4e-05 62_[+4]_10 chr1:18748653-18748733 1.4e-05 48_[+4]_24 chr16:17684955-17685035 1.4e-05 41_[+4]_31 chr1:147143972-147144052 1.4e-05 66_[+4]_6 chr12:127437993-12743807 1.4e-05 40_[+4]_32 chr6:14077543-14077623 1.4e-05 47_[+4]_25 chr10:15669710-15669790 1.4e-05 67_[+4]_5 chr21:30164069-30164149 1.4e-05 35_[+4]_37 chr20:9006489-9006569 1.4e-05 34_[+4]_38 chr10:21368155-21368235 1.4e-05 63_[+4]_9 chr16:50491967-50492047 1.4e-05 36_[+4]_36 chr7:100795415-100795495 1.4e-05 55_[+4]_17 chr10:125701743-12570182 1.4e-05 33_[+4]_39 chr8:29474728-29474808 1.4e-05 55_[+4]_17 chr2:152899223-152899303 1.4e-05 31_[+4]_41 chr6:18242808-18242888 1.4e-05 62_[+4]_10 chr2:162239393-162239473 3e-05 69_[+4]_3 chr1:55359153-55359233 3e-05 45_[+4]_27 chr4:184256760-184256840 3e-05 37_[+4]_35 chr1:204141141-204141221 3e-05 59_[+4]_13 chr8:90809101-90809181 3e-05 24_[+4]_48 chr6:136726728-136726808 6.2e-05 55_[+4]_17 chr2:152528976-152529056 6.2e-05 19_[+4]_53 chrX:67682137-67682217 6.2e-05 41_[+4]_31 chr4:57567013-57567093 6.2e-05 41_[+4]_31 chr3:125919525-125919605 6.2e-05 53_[+4]_19 chr1:53605659-53605739 6.2e-05 28_[+4]_44 chr2:171201424-171201504 7.6e-05 69_[+4]_3 chr8:20134419-20134499 7.6e-05 61_[+4]_11 chr1:223079690-223079770 9.2e-05 46_[+4]_26 chr9:33703571-33703651 9.2e-05 71_[+4]_1 chr22:22378443-22378523 0.00011 46_[+4]_26 chr14:102928013-10292809 0.00011 71_[+4]_1 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCATCTTG MEME-4 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF CCATCTTG width=8 seqs=36 chrX:3619582-3619662 ( 64) CCATCTTG 1 chr5:102393011-102393091 ( 36) CCATCTTG 1 chr17:77007687-77007767 ( 66) CCATCTTG 1 chr1:181143038-181143118 ( 63) CCATCTTG 1 chr1:18748653-18748733 ( 49) CCATCTTG 1 chr16:17684955-17685035 ( 42) CCATCTTG 1 chr1:147143972-147144052 ( 67) CCATCTTG 1 chr12:127437993-12743807 ( 41) CCATCTTG 1 chr6:14077543-14077623 ( 48) CCATCTTG 1 chr10:15669710-15669790 ( 68) CCATCTTG 1 chr21:30164069-30164149 ( 36) CCATCTTG 1 chr20:9006489-9006569 ( 35) CCATCTTG 1 chr10:21368155-21368235 ( 64) CCATCTTG 1 chr16:50491967-50492047 ( 37) CCATCTTG 1 chr7:100795415-100795495 ( 56) CCATCTTG 1 chr10:125701743-12570182 ( 34) CCATCTTG 1 chr8:29474728-29474808 ( 56) CCATCTTG 1 chr2:152899223-152899303 ( 32) CCATCTTG 1 chr6:18242808-18242888 ( 63) CCATCTTG 1 chr2:162239393-162239473 ( 70) CCATTTTG 1 chr1:55359153-55359233 ( 46) CCATTTTG 1 chr4:184256760-184256840 ( 38) CCATTTTG 1 chr1:204141141-204141221 ( 60) CCATTTTG 1 chr8:90809101-90809181 ( 25) CCATTTTG 1 chr6:136726728-136726808 ( 56) CCATATTG 1 chr2:152528976-152529056 ( 20) CCATCTTT 1 chrX:67682137-67682217 ( 42) CCATCTTT 1 chr4:57567013-57567093 ( 42) CCATCTTT 1 chr3:125919525-125919605 ( 54) CCATATTG 1 chr1:53605659-53605739 ( 29) CCATATTG 1 chr2:171201424-171201504 ( 70) CCATGTTG 1 chr8:20134419-20134499 ( 62) CCATGTTG 1 chr1:223079690-223079770 ( 47) CCATCTTA 1 chr9:33703571-33703651 ( 72) CCATCTTA 1 chr22:22378443-22378523 ( 47) CCATCCTG 1 chr14:102928013-10292809 ( 72) CCATCTCG 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCATCTTG MEME-4 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 9.11739 E= 1.3e-022 -1181 215 -1181 -1181 -1181 215 -1181 -1181 188 -1181 -1181 -1181 -1181 -1181 -1181 192 -171 168 -209 -93 -1181 -302 -1181 187 -1181 -302 -1181 187 -229 -1181 186 -167 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCATCTTG MEME-4 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 36 E= 1.3e-022 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.083333 0.722222 0.055556 0.138889 0.000000 0.027778 0.000000 0.972222 0.000000 0.027778 0.000000 0.972222 0.055556 0.000000 0.861111 0.083333 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCATCTTG MEME-4 regular expression -------------------------------------------------------------------------------- CCATCTTG -------------------------------------------------------------------------------- Time 16.03 secs. ******************************************************************************** ******************************************************************************** MOTIF GAACCAGA MEME-5 width = 8 sites = 22 llr = 230 E-value = 6.8e-014 ******************************************************************************** -------------------------------------------------------------------------------- Motif GAACCAGA MEME-5 Description -------------------------------------------------------------------------------- Simplified A :aa:1a:a pos.-specific C :::a9:1: probability G a:::::9: matrix T :::::::: bits 2.1 * * 1.9 **** * * 1.7 ******** 1.5 ******** Relative 1.3 ******** Entropy 1.1 ******** (15.1 bits) 0.9 ******** 0.6 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel GAACCAGA consensus sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GAACCAGA MEME-5 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chrX:3619582-3619662 50 1.56e-05 agcggcatct gaaccaga gcaactccat chr1:223079690-223079770 33 1.56e-05 agaggcgttt gaaccaga gcaactccat chr16:12704956-12705036 63 1.56e-05 agagggattt gaaccaga gcaactccat chr17:77007687-77007767 52 1.56e-05 agaggccttc gaaccaga gcaacaccat chr1:181143038-181143118 49 1.56e-05 aaaggcgttg gaaccaga gtgactccat chr3:32090136-32090216 60 1.56e-05 agaggtgttt gaaccaga gcaactccat chr16:17684955-17685035 28 1.56e-05 agaggcattt gaaccaga gtgaccccat chr12:127437993-12743807 27 1.56e-05 agaggcactt gaaccaga gcaactccat chr10:15669710-15669790 54 1.56e-05 agaggcattt gaaccaga gcaactccat chrX:67682137-67682217 28 1.56e-05 agaggcactc gaaccaga gtgactccat chr16:50491967-50492047 23 1.56e-05 agaggcattc gaaccaga gcgactccat chr8:29474728-29474808 42 1.56e-05 agagatgttc gaaccaga gcaactccat chr2:152899223-152899303 18 1.56e-05 agacgcgttt gaaccaga gcaactccat chr8:20134419-20134499 48 1.56e-05 agaggcattt gaaccaga gcaactccat chr9:33703571-33703651 58 1.56e-05 agagacatat gaaccaga gcaactccat chr12:65955728-65955808 66 1.56e-05 agaggcattt gaaccaga gcgactc chr8:90809101-90809181 11 1.56e-05 agaggtgttt gaaccaga gcaactccat chr10:91115233-91115313 62 1.56e-05 agagacattt gaaccaga gaaactccat chr10:125701743-12570182 20 3.03e-05 agaggcatct gaaccaca gtgactccat chr6:25866424-25866504 69 3.03e-05 acacgataag gaaccaca aaca chr1:247531151-247531231 72 4.92e-05 agatatattt gaacaaga g chr1:18748653-18748733 35 4.92e-05 aggggcgttt gaacaaga gtgactccat -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GAACCAGA MEME-5 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chrX:3619582-3619662 1.6e-05 49_[+5]_23 chr1:223079690-223079770 1.6e-05 32_[+5]_40 chr16:12704956-12705036 1.6e-05 62_[+5]_10 chr17:77007687-77007767 1.6e-05 51_[+5]_21 chr1:181143038-181143118 1.6e-05 48_[+5]_24 chr3:32090136-32090216 1.6e-05 59_[+5]_13 chr16:17684955-17685035 1.6e-05 27_[+5]_45 chr12:127437993-12743807 1.6e-05 26_[+5]_46 chr10:15669710-15669790 1.6e-05 53_[+5]_19 chrX:67682137-67682217 1.6e-05 27_[+5]_45 chr16:50491967-50492047 1.6e-05 22_[+5]_50 chr8:29474728-29474808 1.6e-05 41_[+5]_31 chr2:152899223-152899303 1.6e-05 17_[+5]_55 chr8:20134419-20134499 1.6e-05 47_[+5]_25 chr9:33703571-33703651 1.6e-05 57_[+5]_15 chr12:65955728-65955808 1.6e-05 65_[+5]_7 chr8:90809101-90809181 1.6e-05 10_[+5]_62 chr10:91115233-91115313 1.6e-05 61_[+5]_11 chr10:125701743-12570182 3e-05 19_[+5]_53 chr6:25866424-25866504 3e-05 68_[+5]_4 chr1:247531151-247531231 4.9e-05 71_[+5]_1 chr1:18748653-18748733 4.9e-05 34_[+5]_38 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GAACCAGA MEME-5 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF GAACCAGA width=8 seqs=22 chrX:3619582-3619662 ( 50) GAACCAGA 1 chr1:223079690-223079770 ( 33) GAACCAGA 1 chr16:12704956-12705036 ( 63) GAACCAGA 1 chr17:77007687-77007767 ( 52) GAACCAGA 1 chr1:181143038-181143118 ( 49) GAACCAGA 1 chr3:32090136-32090216 ( 60) GAACCAGA 1 chr16:17684955-17685035 ( 28) GAACCAGA 1 chr12:127437993-12743807 ( 27) GAACCAGA 1 chr10:15669710-15669790 ( 54) GAACCAGA 1 chrX:67682137-67682217 ( 28) GAACCAGA 1 chr16:50491967-50492047 ( 23) GAACCAGA 1 chr8:29474728-29474808 ( 42) GAACCAGA 1 chr2:152899223-152899303 ( 18) GAACCAGA 1 chr8:20134419-20134499 ( 48) GAACCAGA 1 chr9:33703571-33703651 ( 58) GAACCAGA 1 chr12:65955728-65955808 ( 66) GAACCAGA 1 chr8:90809101-90809181 ( 11) GAACCAGA 1 chr10:91115233-91115313 ( 62) GAACCAGA 1 chr10:125701743-12570182 ( 20) GAACCACA 1 chr6:25866424-25866504 ( 69) GAACCACA 1 chr1:247531151-247531231 ( 72) GAACAAGA 1 chr1:18748653-18748733 ( 35) GAACAAGA 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GAACCAGA MEME-5 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 10.0499 E= 6.8e-014 -1110 -1110 208 -1110 188 -1110 -1110 -1110 188 -1110 -1110 -1110 -1110 215 -1110 -1110 -158 201 -1110 -1110 188 -1110 -1110 -1110 -1110 -131 194 -1110 188 -1110 -1110 -1110 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GAACCAGA MEME-5 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 22 E= 6.8e-014 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.090909 0.909091 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.090909 0.909091 0.000000 1.000000 0.000000 0.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GAACCAGA MEME-5 regular expression -------------------------------------------------------------------------------- GAACCAGA -------------------------------------------------------------------------------- Time 19.58 secs. ******************************************************************************** ******************************************************************************** SUMMARY OF MOTIFS ******************************************************************************** -------------------------------------------------------------------------------- Combined block diagrams: non-overlapping sites with p-value < 0.0001 -------------------------------------------------------------------------------- SEQUENCE NAME COMBINED P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr3:40309932-40310012 4.78e-01 80 chr20:31840425-31840505 9.18e-01 80 chr4:26932838-26932918 8.22e-01 80 chr6:4829496-4829576 3.49e-01 80 chr7:64766111-64766191 2.43e-02 71_[+2(4.16e-05)]_1 chr17:61373662-61373742 8.68e-01 80 chr9:95057751-95057831 4.44e-01 80 chr11:74136304-74136384 6.34e-01 80 chr4:89961241-89961321 6.15e-01 80 chr9:96950689-96950769 6.98e-01 80 chrX:38629617-38629697 5.95e-01 80 chr17:71221275-71221355 6.87e-01 80 chr7:7214809-7214889 4.12e-01 80 chr9:115981629-115981709 4.12e-01 80 chr20:45318991-45319071 9.06e-01 80 chr12:108653975-10865405 9.13e-01 80 chr3:17756095-17756175 9.38e-01 80 chr9:6210125-6210205 3.55e-01 80 chr1:236673375-236673455 8.95e-02 80 chr8:49944967-49945047 1.18e-01 42_[+2(4.16e-05)]_30 chr3:5157424-5157504 3.32e-01 80 chr12:116837019-11683709 5.85e-01 80 chr17:42730257-42730337 8.72e-01 80 chr1:9138482-9138562 8.51e-05 8_[+2(1.40e-05)]_5_[+3(1.16e-05)]_\ 51 chr16:22365055-22365135 6.44e-02 40_[+3(2.38e-05)]_32 chr1:234472254-234472334 7.00e-01 80 chr2:26055925-26056005 5.37e-01 80 chr6:25866424-25866504 1.22e-02 68_[+5(3.03e-05)]_4 chr6:91032855-91032935 6.41e-02 80 chr10:91115233-91115313 6.46e-02 61_[+5(1.56e-05)]_11 chr6:18242808-18242888 2.68e-02 62_[+4(1.37e-05)]_10 chrX:5225009-5225089 7.64e-01 80 chr17:76439095-76439175 3.15e-01 80 chr6:19935582-19935662 6.00e-01 80 chr19:11874091-11874171 6.42e-01 80 chr2:102875202-102875282 7.41e-01 80 chr20:56832034-56832114 3.83e-03 80 chr5:31362428-31362508 6.41e-06 [+1(1.68e-05)]_4_[+2(1.40e-05)]_5_\ [+3(1.16e-05)]_47 chr7:129844607-129844687 1.84e-01 80 chr17:5317111-5317191 8.18e-01 80 chr1:116417331-116417411 2.49e-05 3_[+2(2.59e-05)]_5_[+3(1.16e-05)]_\ 15_[+1(9.87e-05)]_33 chr11:45479435-45479515 2.87e-01 80 chr17:56991451-56991531 3.94e-01 80 chr15:39689359-39689439 3.54e-02 80 chr12:76116598-76116678 8.55e-01 80 chr15:28177905-28177985 7.50e-01 80 chr10:102647687-10264776 2.13e-02 25_[+1(6.47e-05)]_47 chr20:3646642-3646722 1.37e-05 8_[+1(5.08e-05)]_4_[+2(1.40e-05)]_5_\ [+3(1.16e-05)]_39 chr1:201521171-201521251 3.23e-01 80 chr2:11262767-11262847 5.30e-04 1_[+2(5.81e-05)]_5_[+3(1.16e-05)]_\ 58 chr1:201524310-201524390 6.97e-01 80 chr5:16736501-16736581 2.49e-02 80 chr16:55410646-55410726 4.91e-03 9_[+2(2.59e-05)]_63 chr7:91481810-91481890 6.18e-02 80 chrX:64821698-64821778 8.62e-03 3_[+2(4.16e-05)]_69 chr15:59461816-59461896 5.39e-01 80 chr7:123262959-123263039 6.23e-02 80 chr8:90809101-90809181 1.19e-03 10_[+5(1.56e-05)]_6_[+4(2.98e-05)]_\ 48 chr7:123633141-123633221 7.82e-06 39_[+1(1.68e-05)]_4_[+2(1.40e-05)]_\ 5_[+3(5.15e-05)]_8 chr1:53605659-53605739 7.21e-02 28_[+4(6.16e-05)]_44 chr12:49412886-49412966 3.74e-02 80 chr12:65955728-65955808 6.25e-02 65_[+5(1.56e-05)]_7 chr2:167267494-167267574 5.45e-01 80 chr9:33703571-33703651 2.56e-04 57_[+5(1.56e-05)]_6_[+4(9.16e-05)]_\ 1 chr15:60314141-60314221 7.84e-04 53_[+3(1.16e-05)]_19 chr2:68851111-68851191 1.81e-01 80 chr1:174965713-174965793 1.61e-02 80 chr15:81062327-81062407 9.70e-05 38_[+1(1.68e-05)]_34 chr10:21379613-21379693 3.48e-01 80 chr11:35358778-35358858 6.49e-01 80 chr3:45147756-45147836 4.25e-03 11_[+3(9.29e-05)]_61 chr11:72447922-72448002 1.33e-02 80 chr6:43538812-43538892 2.57e-01 80 chr4:38939014-38939094 3.30e-01 80 chr8:20134419-20134499 2.65e-03 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******************************************************************************** CPU: c22n05.farnam.hpc.yale.internal ********************************************************************************