******************************************************************************** MEME - Motif discovery tool ******************************************************************************** MEME version 5.3.3 (Release date: Sun Feb 7 15:39:52 2021 -0800) For further information on how to interpret these results please access https://meme-suite.org/meme. To get a copy of the MEME Suite software please access https://meme-suite.org. ******************************************************************************** ******************************************************************************** REFERENCE ******************************************************************************** If you use this program in your research, please cite: Timothy L. Bailey and Charles Elkan, "Fitting a mixture model by expectation maximization to discover motifs in biopolymers", Proceedings of the Second International Conference on Intelligent Systems for Molecular Biology, pp. 28-36, AAAI Press, Menlo Park, California, 1994. ******************************************************************************** ******************************************************************************** TRAINING SET ******************************************************************************** PRIMARY SEQUENCES= ../result/final_prediction/K562/fasta/RankLinear0.6_40/ZFX.fasta CONTROL SEQUENCES= --none-- ALPHABET= ACGT Sequence name Weight Length Sequence name Weight Length ------------- ------ ------ ------------- ------ ------ chr10:181803-181883 1.0000 80 chr2:206950476-206950556 1.0000 80 chrX:24168008-24168088 1.0000 80 chr19:4065642-4065722 1.0000 80 chr8:38239417-38239497 1.0000 80 chr5:137688600-137688680 1.0000 80 chr11:63606777-63606857 1.0000 80 chr16:58034377-58034457 1.0000 80 chr22:41698316-41698396 1.0000 80 chr10:103454039-10345411 1.0000 80 chr3:182698024-182698104 1.0000 80 chr3:9439543-9439623 1.0000 80 chr15:45459098-45459178 1.0000 80 chr19:16738435-16738515 1.0000 80 chr19:5293126-5293206 1.0000 80 chr15:57025396-57025476 1.0000 80 chr10:28822967-28823047 1.0000 80 chr6:33756547-33756627 1.0000 80 chr7:129251800-129251880 1.0000 80 chr16:30905272-30905352 1.0000 80 chr7:129252002-129252082 1.0000 80 chr14:31676674-31676754 1.0000 80 chr5:180688700-180688780 1.0000 80 chr5:36877486-36877566 1.0000 80 chr11:65292727-65292807 1.0000 80 chr13:53024480-53024560 1.0000 80 chr19:18943124-18943204 1.0000 80 chr2:85198927-85199007 1.0000 80 chr10:6131198-6131278 1.0000 80 chr5:56247685-56247765 1.0000 80 chr14:69618548-69618628 1.0000 80 chr3:25705949-25706029 1.0000 80 chr15:66586172-66586252 1.0000 80 chr5:141488656-141488736 1.0000 80 chr7:72936244-72936324 1.0000 80 chr10:33247060-33247140 1.0000 80 chr6:24495284-24495364 1.0000 80 chr2:18741643-18741723 1.0000 80 chr18:72264573-72264653 1.0000 80 chr7:39989632-39989712 1.0000 80 chr1:173990986-173991066 1.0000 80 chr2:183902848-183902928 1.0000 80 chr19:48996908-48996988 1.0000 80 chr19:4969296-4969376 1.0000 80 chr12:69633703-69633783 1.0000 80 chr1:224621934-224622014 1.0000 80 chr4:110355118-110355198 1.0000 80 chr1:185125629-185125709 1.0000 80 chr6:157100637-157100717 1.0000 80 chr10:22629703-22629783 1.0000 80 chr7:56032434-56032514 1.0000 80 chr12:56651934-56652014 1.0000 80 chr1:176175894-176175974 1.0000 80 chr4:39978603-39978683 1.0000 80 chr3:196729862-196729942 1.0000 80 chr1:197744073-197744153 1.0000 80 chr7:149194518-149194598 1.0000 80 chr19:38146096-38146176 1.0000 80 chr22:35653632-35653712 1.0000 80 chr7:148396167-148396247 1.0000 80 chr1:154193702-154193782 1.0000 80 chr10:65281339-65281419 1.0000 80 chr7:148959444-148959524 1.0000 80 chr12:54412060-54412140 1.0000 80 chr7:148396374-148396454 1.0000 80 chr1:87170742-87170822 1.0000 80 chr1:151299859-151299939 1.0000 80 chr16:57514217-57514297 1.0000 80 chr10:94051119-94051199 1.0000 80 chr1:23670380-23670460 1.0000 80 chr16:48278523-48278603 1.0000 80 chr17:47439123-47439203 1.0000 80 chr6:158244290-158244370 1.0000 80 chr19:48894041-48894121 1.0000 80 chr1:22778803-22778883 1.0000 80 chr11:47788505-47788585 1.0000 80 chr17:61851750-61851830 1.0000 80 chr9:114245580-114245660 1.0000 80 chr13:111358351-11135843 1.0000 80 chr8:42995844-42995924 1.0000 80 chr2:64246566-64246646 1.0000 80 chr20:33413228-33413308 1.0000 80 chr15:63797055-63797135 1.0000 80 chr15:65477469-65477549 1.0000 80 chr19:15442925-15443005 1.0000 80 chr15:78730791-78730871 1.0000 80 chr3:47844801-47844881 1.0000 80 chr11:16760369-16760449 1.0000 80 chr16:69345424-69345504 1.0000 80 chr3:51428901-51428981 1.0000 80 chr8:48173319-48173399 1.0000 80 chr3:47845001-47845081 1.0000 80 chr1:6685379-6685459 1.0000 80 chr9:95896454-95896534 1.0000 80 chr21:38445139-38445219 1.0000 80 chr19:30206214-30206294 1.0000 80 chr19:4123900-4123980 1.0000 80 chr1:16010795-16010875 1.0000 80 chr16:67927365-67927445 1.0000 80 chr1:36621746-36621826 1.0000 80 chr2:105946268-105946348 1.0000 80 chr1:46767487-46767567 1.0000 80 chr19:8070322-8070402 1.0000 80 chr10:11784520-11784600 1.0000 80 chr14:24899230-24899310 1.0000 80 chr1:9294911-9294991 1.0000 80 chr4:99182076-99182156 1.0000 80 chr11:126152965-12615304 1.0000 80 chrX:118709012-118709092 1.0000 80 chr9:104161274-104161354 1.0000 80 chr2:24346596-24346676 1.0000 80 chr9:33817619-33817699 1.0000 80 chr6:99395666-99395746 1.0000 80 chr16:66864617-66864697 1.0000 80 chr21:34775882-34775962 1.0000 80 chr10:13389403-13389483 1.0000 80 chr19:18942914-18942994 1.0000 80 chrX:56590086-56590166 1.0000 80 chr8:59572026-59572106 1.0000 80 chr5:177659591-177659671 1.0000 80 chr2:61921716-61921796 1.0000 80 chr15:52860951-52861031 1.0000 80 chr7:73588795-73588875 1.0000 80 chr1:1093058-1093138 1.0000 80 chr7:156931144-156931224 1.0000 80 chr1:212003762-212003842 1.0000 80 chr6:76311957-76312037 1.0000 80 chr6:90062303-90062383 1.0000 80 chr22:46068094-46068174 1.0000 80 chr7:94139406-94139486 1.0000 80 chr15:40226441-40226521 1.0000 80 chr5:176561157-176561237 1.0000 80 chr2:61404628-61404708 1.0000 80 chr20:32951482-32951562 1.0000 80 chr20:57617616-57617696 1.0000 80 chr19:47249409-47249489 1.0000 80 chr2:74405711-74405791 1.0000 80 chrX:153744468-153744548 1.0000 80 chr12:74931748-74931828 1.0000 80 chr3:47205107-47205187 1.0000 80 chr10:116581864-11658194 1.0000 80 chr15:41233957-41234037 1.0000 80 chr1:24970106-24970186 1.0000 80 chr3:47204906-47204986 1.0000 80 chr5:139486990-139487070 1.0000 80 chr12:112546346-11254642 1.0000 80 chr2:75874158-75874238 1.0000 80 chr5:39202570-39202650 1.0000 80 chr7:40173981-40174061 1.0000 80 chr17:26220080-26220160 1.0000 80 chr11:118661445-11866152 1.0000 80 chr3:15247953-15248033 1.0000 80 chr15:83478660-83478740 1.0000 80 chrX:54070568-54070648 1.0000 80 chr9:110046063-110046143 1.0000 80 chr7:6746216-6746296 1.0000 80 chr14:69864749-69864829 1.0000 80 chr20:56884845-56884925 1.0000 80 chr15:31283999-31284079 1.0000 80 chr6:18264552-18264632 1.0000 80 chr3:150321315-150321395 1.0000 80 chr10:131908886-13190896 1.0000 80 chr20:56099786-56099866 1.0000 80 chr17:11924361-11924441 1.0000 80 chr2:176045835-176045915 1.0000 80 chr20:62152136-62152216 1.0000 80 chr22:20067917-20067997 1.0000 80 chr10:25012130-25012210 1.0000 80 chr19:42746653-42746733 1.0000 80 chr5:137089792-137089872 1.0000 80 chr16:67596873-67596953 1.0000 80 chr1:42922398-42922478 1.0000 80 chr11:2422134-2422214 1.0000 80 chr7:131013013-131013093 1.0000 80 chr5:32312679-32312759 1.0000 80 chr4:103422609-103422689 1.0000 80 chr3:140661154-140661234 1.0000 80 chr1:65432120-65432200 1.0000 80 chr7:87849141-87849221 1.0000 80 chr17:45266377-45266457 1.0000 80 chr5:168006316-168006396 1.0000 80 chr10:115614627-11561470 1.0000 80 chr8:91658076-91658156 1.0000 80 chr1:53192255-53192335 1.0000 80 chr6:157098610-157098690 1.0000 80 chr16:30913648-30913728 1.0000 80 chr6:52442113-52442193 1.0000 80 chr1:46663960-46664040 1.0000 80 chr11:107992461-10799254 1.0000 80 chr1:117909652-117909732 1.0000 80 chr10:7830267-7830347 1.0000 80 chr14:89029574-89029654 1.0000 80 chr11:66247601-66247681 1.0000 80 chr19:14229143-14229223 1.0000 80 chr1:41707529-41707609 1.0000 80 chr15:65425505-65425585 1.0000 80 chr15:85291581-85291661 1.0000 80 chr10:75910345-75910425 1.0000 80 chr3:45731069-45731149 1.0000 80 chr12:53846281-53846361 1.0000 80 chr2:37423845-37423925 1.0000 80 chr12:27933217-27933297 1.0000 80 chr11:64684638-64684718 1.0000 80 chr3:38495661-38495741 1.0000 80 chr19:29703749-29703829 1.0000 80 chr5:176433509-176433589 1.0000 80 chr3:182511642-182511722 1.0000 80 chr5:77071758-77071838 1.0000 80 chr14:23771202-23771282 1.0000 80 chr1:247495328-247495408 1.0000 80 chr3:122233487-122233567 1.0000 80 chr16:4321931-4322011 1.0000 80 chr17:47592772-47592852 1.0000 80 chr11:130786133-13078621 1.0000 80 chr18:48494494-48494574 1.0000 80 chr2:128145144-128145224 1.0000 80 chr14:105767050-10576713 1.0000 80 chr12:54389534-54389614 1.0000 80 chr8:97657475-97657555 1.0000 80 chr16:4674883-4674963 1.0000 80 chr5:72794557-72794637 1.0000 80 chr4:699746-699826 1.0000 80 chr12:125051897-12505197 1.0000 80 chr2:75873956-75874036 1.0000 80 chr11:13690550-13690630 1.0000 80 chr3:160282788-160282868 1.0000 80 chr7:134001465-134001545 1.0000 80 chr1:67519707-67519787 1.0000 80 chr7:140372929-140373009 1.0000 80 chr2:98612156-98612236 1.0000 80 chr5:176074704-176074784 1.0000 80 chr17:44344101-44344181 1.0000 80 chr6:126111572-126111652 1.0000 80 chr7:56032639-56032719 1.0000 80 chr4:77135146-77135226 1.0000 80 chr12:69864192-69864272 1.0000 80 chr6:20403537-20403617 1.0000 80 chr3:193859578-193859658 1.0000 80 chr8:61429955-61430035 1.0000 80 chr20:30311150-30311230 1.0000 80 chr2:20550170-20550250 1.0000 80 chr16:57279190-57279270 1.0000 80 chr16:447244-447324 1.0000 80 chr11:11863737-11863817 1.0000 80 chr7:73097539-73097619 1.0000 80 chr21:43374012-43374092 1.0000 80 chr22:22862841-22862921 1.0000 80 chr11:17297866-17297946 1.0000 80 chr14:54907852-54907932 1.0000 80 chr5:162887049-162887129 1.0000 80 ******************************************************************************** ******************************************************************************** COMMAND LINE SUMMARY ******************************************************************************** This information can also be useful in the event you wish to report a problem with the MEME software. command: meme -oc ../result/final_prediction/K562/inference_raw/MEME/RankLinear0.6_40_ZFX/ -dna -nmotifs 5 -w 8 -maxsize 250000 -nostatus ../result/final_prediction/K562/fasta/RankLinear0.6_40/ZFX.fasta model: mod= zoops nmotifs= 5 evt= inf objective function: em= E-value of product of p-values starts= E-value of product of p-values strands: + width: minw= 8 maxw= 8 nsites: minsites= 2 maxsites= 250 wnsites= 0.8 theta: spmap= uni spfuzz= 0.5 em: prior= dirichlet b= 0.01 maxiter= 50 distance= 1e-05 trim: wg= 11 ws= 1 endgaps= yes data: n= 20000 N= 250 sample: seed= 0 hsfrac= 0 searchsize= 20000 norand= no csites= 1000 Letter frequencies in dataset: A 0.122 C 0.383 G 0.38 T 0.115 Background letter frequencies (from file dataset with add-one prior applied): A 0.122 C 0.383 G 0.38 T 0.115 Background model order: 0 ******************************************************************************** ******************************************************************************** MOTIF CBVGGCCT MEME-1 width = 8 sites = 223 llr = 1247 E-value = 3.7e-061 ******************************************************************************** -------------------------------------------------------------------------------- Motif CBVGGCCT MEME-1 Description -------------------------------------------------------------------------------- Simplified A 114::::: pos.-specific C 733::aa2 probability G :43aa::2 matrix T 22:::::6 bits 3.1 2.8 2.5 2.2 Relative 1.9 Entropy 1.6 (8.1 bits) 1.2 ***** 0.9 ***** 0.6 * ****** 0.3 * ****** 0.0 -------- Multilevel CGAGGCCT consensus TCC sequence TG -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CBVGGCCT MEME-1 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr11:11863737-11863817 62 3.93e-06 AGGTTAGGCC TTAGGCCT GCGGCCGCTC chr11:118661445-11866152 29 3.93e-06 CGGCCAGGCC TTAGGCCT CCGCCCGAGA chr3:45731069-45731149 71 1.70e-05 GCGGCCTCTC CTAGGCCT CG chr2:176045835-176045915 33 1.70e-05 GGCCTGACAG CTAGGCCT CGGCTGCTCT chr12:74931748-74931828 59 1.70e-05 TGAAAGGCCT CTAGGCCT AGGCGCGGCC chr19:18942914-18942994 35 1.70e-05 GGCCTGCGGC CTAGGCCT CAGCGCGGCG chr3:47844801-47844881 56 1.70e-05 GCCGGGCATC CTAGGCCT GCCCGGGAAG chr19:48894041-48894121 25 1.70e-05 CCGTCCCAGA CTAGGCCT CATGGCTACC chr11:16760369-16760449 50 3.00e-05 GGCTGAGGGT TGAGGCCT ACTAAAGCCT chr9:114245580-114245660 10 3.00e-05 GTGCAAACC TGAGGCCT ACAAACGCCA chr1:173990986-173991066 39 3.00e-05 TGCAGAGGCC TGAGGCCT AAAGGACGCC chr11:17297866-17297946 1 7.33e-05 . CGAGGCCT GTGGGCGAGA chr20:30311150-30311230 19 7.33e-05 GAAGAGGGGT CGAGGCCT GCTCGACGGC chr6:126111572-126111652 30 7.33e-05 CACAAAGGGC CGAGGCCT GCGGAGGCCG chr1:42922398-42922478 48 7.33e-05 CAACCTCGGC CGAGGCCT TCCTAGCCGC chr14:69864749-69864829 18 7.33e-05 ACCGGGGCTC CGAGGCCT AGAGTCAGGC chr1:6685379-6685459 33 7.33e-05 GGACCGACTC CGAGGCCT TGGCGCGCCG chr15:65477469-65477549 28 7.33e-05 GGCATCTCCG CGAGGCCT AGGCCGGGGC chr4:39978603-39978683 33 7.33e-05 AAACCAGACC CGAGGCCT ATAGGGCTCG chr14:69618548-69618628 7 7.33e-05 GGAGAG CGAGGCCT ACACCGCCCG chr19:5293126-5293206 57 7.33e-05 CCAGGCCCCG CGAGGCCT CCACAGGGCC chr5:141488656-141488736 11 8.63e-05 GCTGGCCGCC TCAGGCCT CTCTGGCCGG chr6:20403537-20403617 52 1.30e-04 GCCCAAGcgc ccaggcct tcctcgccgg chr17:44344101-44344181 22 1.30e-04 GAGGGGGCGC CCAGGCCT CAGCCGCCGG chr14:105767050-10576713 13 1.30e-04 gcccagccgc ccaggcct cgccgctctc chr16:4321931-4322011 49 1.30e-04 AGAGTCACGT CCAGGCCT CGCTAGTAAA chr19:14229143-14229223 45 1.30e-04 GCGGCCGAGG CCAGGCCT GCTTGGGGGC chr6:52442113-52442193 43 1.30e-04 AGGCGGGCGC CCAGGCCT GCCCGGACAG chr17:26220080-26220160 34 1.30e-04 GGCCGCCCGG CCAGGCCT GCGTCAAGCC chrX:56590086-56590166 37 1.30e-04 CGGCCTACGC CCAGGCCT TTCTCCACCG chr13:111358351-11135843 59 1.30e-04 AGCGGGGGGC CCAGGCCT GGGCCGCGCG chr7:148396374-148396454 1 1.30e-04 . CCAGGCCT GGACTACGCA chr19:38146096-38146176 50 1.30e-04 GCCCGGGCCT CCAGGCCT CAGGGCTGCA chr19:4969296-4969376 52 1.30e-04 gACTCGAGGC CCAGGCCT CGGGCGCGGC chr15:57025396-57025476 8 1.30e-04 GCGCGGC CCAGGCCT GCAGCAGCCG chr5:137089792-137089872 34 1.34e-04 TATCGTTGGT TAAGGCCT CTACACAGCT chr12:53846281-53846361 72 1.60e-04 AGGCCTCGCG CAAGGCCT A chr15:65425505-65425585 18 1.60e-04 CGCCGTCGGC TTCGGCCT CGCGCAGGGC chr5:139486990-139487070 64 1.60e-04 AGAGCCTGGC TTCGGCCT TCAGAAGCC chr20:32951482-32951562 29 1.60e-04 TCTCCAGCGG TTCGGCCT Acgcgcgggg chr3:51428901-51428981 46 1.60e-04 gggcggcgcA CAAGGCCT CTGGCGGCGC chr11:66247601-66247681 8 2.06e-04 GCGCCGT CTCGGCCT GGGCTTGGTG chr4:103422609-103422689 23 2.06e-04 cgccgcagcc ctcggcct gcacgcagcc chr19:47249409-47249489 12 2.06e-04 ACTCGGCGCG CTCGGCCT CCCAGCGGGC chr5:176561157-176561237 68 2.06e-04 cTGCGAACAC CTCGGCCT CCGCC chr19:16738435-16738515 42 2.06e-04 GCACGGAAGC CTCGGCCT CACGTACCGA chr7:73097539-73097619 23 2.18e-04 CCGCCTTGAT TTGGGCCT GCGTGGCTGT chr20:56099786-56099866 37 2.18e-04 CAGGCAGGCT TTGGGCCT AGTGGCCTCG chrX:54070568-54070648 18 2.18e-04 AGACCGCGGC TTGGGCCT AGTCTGGCGG chr1:22778803-22778883 71 2.18e-04 gactatggcc ttgggcct aa chr3:9439543-9439623 35 2.18e-04 TGGCGCCGCG TTGGGCCT AACTCGAGTC chr12:54389534-54389614 34 2.59e-04 TTCACTCCTG CTGGGCCT CGGGACCTGA chr7:156931144-156931224 4 2.59e-04 GGG CTGGGCCT AGCTGCTCCT chr5:177659591-177659671 16 2.59e-04 GCCGCGCGGG CTGGGCCT CCAAGGCCCC chr21:34775882-34775962 52 2.59e-04 TGAGCCGGGC CTGGGCCT CCGCGGCGGG chrX:118709012-118709092 50 2.59e-04 TTGGGTCTGG CTGGGCCT AGGCGCCTCC chr17:61851750-61851830 48 2.59e-04 GAGGCAACTG CTGGGCCT AGCGAGGGCG chr6:158244290-158244370 11 2.59e-04 CGCCCAGCGG CTGGGCCT GAGCGTCGAG chr18:72264573-72264653 54 2.59e-04 CCGCGCCGTT CTGGGCCT TCTCCGTGTT chr11:65292727-65292807 44 2.59e-04 CGCGGTCGAC CTGGGCCT TGCCTATTCC chr4:699746-699826 66 2.99e-04 CTCCTCAGGC TGCGGCCT CGGCCCG chr5:32312679-32312759 38 2.99e-04 AGCGCGCTCC TGCGGCCT CAGCCCGCCT chr12:112546346-11254642 30 2.99e-04 GGCCCGCGGC TGCGGCCT AGTggcccgc chr10:94051119-94051199 38 2.99e-04 GCCGCCGGAC TGCGGCCT ACTCCGCCGC chr1:197744073-197744153 11 2.99e-04 GGGCAGGCTT TGCGGCCT AGCGCCGTCC chr16:57279190-57279270 6 4.49e-04 GGCTG AGAGGCCT TAAccccgcc chr8:61429955-61430035 29 4.49e-04 TGCGAGCGGC CGCGGCCT GGCCAGGCCC chr8:97657475-97657555 5 4.49e-04 GCCC CGCGGCCT GGCCGGCAAG chr5:176433509-176433589 21 4.49e-04 CGGCGTCGGG AGAGGCCT ACCTTGGCGT chr14:89029574-89029654 31 4.49e-04 GGGTGGACGC CGCGGCCT GGCCTCCGCT chr22:20067917-20067997 36 4.49e-04 gggcgggcgc cgcggcct gcgcgagggc chr17:11924361-11924441 14 4.49e-04 CCCGCGTCGT CGCGGCCT GCCCCAGCGG chr3:150321315-150321395 48 4.49e-04 GCCCCGGCTT CGCGGCCT AAATGGCCGC chr3:47204906-47204986 2 4.49e-04 T CGCGGCCT ACCCTCACCG chr2:61404628-61404708 8 4.49e-04 TAGGCGC CGCGGCCT TTCCTTGTTT chr6:76311957-76312037 43 4.49e-04 GTTCCCCCGG AGAGGCCT GAGAAGCTCG chr19:8070322-8070402 10 4.49e-04 caggcctgc cgcggcct accccgTCGG chr1:16010795-16010875 28 4.49e-04 gcgcacagcc cgcggcct ccttccccgc chr16:48278523-48278603 45 4.49e-04 cggcgggcgg cgcggccT CCTCCGGGGA chr1:87170742-87170822 30 4.49e-04 TGCTGCAGCC AGAGGCCT GGGAGATGGG chr1:154193702-154193782 13 4.49e-04 TGGTTGGGTT CGCGGCCT AGTGGGCCGC chr22:35653632-35653712 44 4.49e-04 CCAGGCCCTT CGCGGCCT AGCCCAGGGG chr10:22629703-22629783 60 4.49e-04 GTGAAAGGAC AGAGGCCT CCTTCCTCGC chr1:224621934-224622014 20 4.49e-04 gacggagggg agAGGCCT GCTCTGCCTG chr2:183902848-183902928 33 4.49e-04 GTCACGGGCC CGCGGCCT TCGCAGCAGC chr15:66586172-66586252 17 4.49e-04 GCGTAGGCCC CGCGGCCT GCGCCCGCTC chr5:56247685-56247765 18 4.49e-04 ccggagccgc cgcggccT AGTCCCGGAG chr2:85198927-85199007 30 4.49e-04 CGGGCCCCAG CGCGGCCT AGCGCTCCCG chr13:53024480-53024560 16 4.49e-04 CACCCCGCAC AGAGGCCT GCCGGGCCGC chr16:58034377-58034457 19 4.49e-04 TCCGCGGCGG CGCGGCCT ACGCGCGCTG chr11:63606777-63606857 15 4.49e-04 tcggagccgg cgcggcct agcccgagcg chr11:13690550-13690630 50 4.89e-04 GGACGTACGG TGGGGCCT GGTTTGCAGC chr1:24970106-24970186 58 4.89e-04 CGCCGGGTCC TGGGGCCT AGCGGAGCCG chr7:140372929-140373009 34 6.65e-04 GGCGCGGGCC TCCGGCCT GAGGCCCGGC chr1:67519707-67519787 18 6.65e-04 GGCCTGGCGG CGGGGCCT AGCGGCTCGG chr6:157098610-157098690 69 6.65e-04 GGCGCTCCGG CGGGGCCT GCGG chr10:115614627-11561470 38 6.65e-04 CCGCAGCCTC TCCGGCCT GCTCCCCGCG chr6:90062303-90062383 5 6.65e-04 TGGC TCCGGCCT CCCGGGCCGC chr1:212003762-212003842 8 6.65e-04 tcctccc cggggcct accgcgccct chr11:126152965-12615304 7 6.65e-04 GGAGAG CGGGGCCT GCGCGCTGCT chr4:99182076-99182156 22 6.65e-04 TCCGGTTAAT TCCGGCCT GTGCGGCCCG chr16:69345424-69345504 54 6.65e-04 CCGAAGGCAG CGGGGCCT GCGGGCCGCA chr15:78730791-78730871 40 6.65e-04 GTGCTCCCCT CGGGGCCT GCCTGCTGGG chr17:47439123-47439203 2 6.65e-04 C TCCGGCCT AGCGCACGCA chr4:110355118-110355198 67 6.65e-04 gggcggagcg cggggcct agcacc chr22:41698316-41698396 30 6.65e-04 CCCGGGGATC CGGGGCCT GCAGCCGGGC chr2:206950476-206950556 15 6.65e-04 ATTCTCCGCC CGGGGCCT GGCGTGGGCC chr10:181803-181883 1 6.65e-04 . CGGGGCCT GCTCGGGCCG chr4:77135146-77135226 29 8.29e-04 CTGAGCCAGG CCCGGCCT GGCCGCTCCC chr7:56032639-56032719 41 8.29e-04 GCGGCGCTGG CCCGGCCT GCAGGGCCCT chr12:125051897-12505197 60 8.29e-04 GCGCAGCAGG CCCGGCCT CGGGTCGGGA chr11:107992461-10799254 53 8.29e-04 ggcgcgcggc TTAGGCCC CAGGACAGTC chr22:46068094-46068174 29 8.29e-04 ccgcggcggc cccggcct ggacccaggc chr15:52860951-52861031 50 8.29e-04 GCCCGCCAGA CCCGGCCT TGGGCAGGGC chr16:66864617-66864697 68 8.29e-04 GCCCGCGCCC TTAGGCCC GGCCC chr2:24346596-24346676 54 8.29e-04 GCCGCAGGCG CCCGGCCT AGTGGGTGGG chr1:46767487-46767567 68 8.29e-04 CAACTCCAAC CCCGGCCT CCCGA chr19:30206214-30206294 39 8.29e-04 CCGAGCTGCG CCCGGCCT TAGGGGGAGC chr19:15442925-15443005 30 8.29e-04 CCCGCGTAgc cccggcct ccccgccccc chr10:6131198-6131278 52 8.29e-04 GCCCGCGGCT TTAGGCCC GTCGCGAGGG chr7:129252002-129252082 1 8.29e-04 . CCCGGCCT TCCCGCAGCT chr19:4065642-4065722 3 8.29e-04 gg cccggccT GCGCTAGGCC chrX:24168008-24168088 51 8.29e-04 GAGGCCGCAG TTAGGCCC GGGGAGGAGC chr3:122233487-122233567 2 9.26e-04 T CTAGGCCC TGCCGGCACC chr5:39202570-39202650 33 9.26e-04 GGCCCAGATT TCGGGCCT AGTGGCTTTA chr20:57617616-57617696 33 9.26e-04 GCTCCCCTCG CTAGGCCC GACGCCTAGA chr8:59572026-59572106 66 9.26e-04 ccggccccga ctaggccc ccgGCTG chr10:33247060-33247140 50 9.26e-04 CGCGGTGGGC TCGGGCCT GCTGTTCCGC chr3:182698024-182698104 13 9.26e-04 GGGCTCCCGA CTAGGCCC GGCTCCGCTC chr2:75873956-75874036 20 1.12e-03 TGCAATGGGC CTAGGCCG GAGTTTCCAA chr3:182511642-182511722 48 1.12e-03 GGGCGCCCGG CTAGGCCG CAGCGGAGAC chr2:37423845-37423925 51 1.12e-03 GCCTGCAGGC CCGGGCCT AGCGTTCCGC chr17:45266377-45266457 39 1.12e-03 GGAGAAGCAG CCGGGCCT AGGCCGCACC chr10:25012130-25012210 45 1.12e-03 ccgggACGCG CTAGGCCG CAGGCTCGGT chr6:18264552-18264632 32 1.12e-03 GCAGGGGCGA CCGGGCCT CCGGCGTCCC chr7:40173981-40174061 4 1.12e-03 CCG TACGGCCT AGACCGGGGC chr2:105946268-105946348 39 1.12e-03 GGGCCCTGCT CCGGGCCT CGGCGTCCCC chr9:95896454-95896534 72 1.12e-03 CCGCCAGGAT CCGGGCCT G chr15:63797055-63797135 26 1.12e-03 CGCGGCTCTG CCGGGCCT GCCGTCTAgg chr8:42995844-42995924 8 1.12e-03 CCGAGCG CTAGGCCG GGCCGGAACC chr11:47788505-47788585 66 1.12e-03 CGTGAGGAGC CTAGGCCG CAAGCCC chr12:56651934-56652014 12 1.12e-03 CAGGCCCAGC CTAGGCCG CACATCCCCG chr7:39989632-39989712 33 1.12e-03 GCGCGAGGCC CTAGGCCG GGAGTTGTTG chr6:24495284-24495364 44 1.12e-03 gtccctgcct ccgggcct gcgcccggcc chr3:25705949-25706029 66 1.12e-03 TCCGCGTCGC CCGGGCCT AGCGCGG chr8:38239417-38239497 25 1.12e-03 CGGAACCGAG CTAGGCCG CATGAAATCC chr19:29703749-29703829 66 1.28e-03 GGCTCACCAT TGAGGCCC ACGGAGG chr10:7830267-7830347 61 1.28e-03 TGTGGGGTCG CAGGGCCT AGCTGGGCCC chr3:140661154-140661234 17 1.28e-03 GGCGAGAGAG TGAGGCCC GGGCAAAGAG chr11:2422134-2422214 48 1.28e-03 AGCATCCTTG TGAGGCCC GGAGGCCTGT chr3:15247953-15248033 10 1.28e-03 GTCCTGCGT CAGGGCCT CCTTCCCTGC chr16:67927365-67927445 40 1.28e-03 CCCCGTGCGC CAGGGCCT ACAGGGTTGG chr3:47845001-47845081 59 1.28e-03 TTTCCCCAGG CAGGGCCT GGAGGAAGCC chr16:57514217-57514297 37 1.28e-03 CGAGCTCACG CAGGGCCT GTTCCCAGGC chr7:149194518-149194598 3 1.28e-03 CC CAGGGCCT GCGGCGCCGT chr10:75910345-75910425 38 1.48e-03 GGGGGGGAAG CGAGGCCC GGGCCAACAG chr5:168006316-168006396 60 1.48e-03 GGCCGCGCGG CGAGGCCC GGCCGGTTCC chr15:83478660-83478740 25 1.48e-03 AGCCCAAGCC TGAGGCCG CCGTCTCCCC chr10:65281339-65281419 32 1.48e-03 GCAGCCGGCG CGAGGCCC AGGGGAGCTG chr16:67596873-67596953 71 1.63e-03 TGTCTGCCCT CGAGGCCG GT chr1:36621746-36621826 22 1.63e-03 AGGGTTGGGC CGAGGCCG GGACTGGGCC chr1:176175894-176175974 37 1.63e-03 ACCGGGCCCC CGAGGCCG CCCGAGCCGG chr1:185125629-185125709 63 1.63e-03 gggctggagc cgaggccg gagtcggagc chr6:33756547-33756627 65 1.63e-03 AGGCCGAGCC CGAGGCCG GCTGGGAG chr10:28822967-28823047 5 1.63e-03 CAGC CGAGGCCG GGGTGGAGGG chrX:153744468-153744548 13 1.68e-03 AGGTTCCCTG TCAGGCCC GCCGACCCGC chr7:134001465-134001545 11 1.91e-03 CCTGCGAACA CCAGGCCC ACCGCCAAGG chr2:128145144-128145224 53 1.91e-03 GGCCTTGGGG CCAGGCCC GTCCCTCTTT chr10:131908886-13190896 63 1.91e-03 TCCCTAACGC CCAGGCCC CGGGGGCTCA chr21:38445139-38445219 38 1.91e-03 GTCGCGGCGC CCAGGCCC CGGGCCCTGC chr2:64246566-64246646 65 1.91e-03 gccTGGGGAA AGCGGCCT TGGCGCAG chr1:151299859-151299939 21 1.91e-03 GGAGGCTGCA CCAGGCCC CGGCTGCGGG chr16:30905272-30905352 65 1.91e-03 aggctccgcg ccaggccc gggcgccg chr2:20550170-20550250 41 2.05e-03 CGAGCGGGCC CCAGGCCG CACCGGCCCG chr15:85291581-85291661 52 2.05e-03 GAGGCCGGGC CCAGGCCG GGGCAGCCCC chr19:42746653-42746733 59 2.05e-03 CTGGCCTCTT CCAGGCCG CGCCGCTCTG chr7:148959444-148959524 40 2.05e-03 CCCGGAAGGC CCAGGCCG CCGCCGCGTG chr19:48996908-48996988 1 2.05e-03 . CCAGGCCG CGACCCCGAA chr2:18741643-18741723 30 2.05e-03 GTGGCGCGGC CCAGGCCG CTGTTCGCCC chr10:103454039-10345411 20 2.05e-03 CCTGGGCCGA CCAggccg cggcgccccg chr9:33817619-33817699 61 2.11e-03 AGCGGAGGGG AGGGGCCT GGTCCGGCCC chr11:130786133-13078621 14 2.30e-03 GCGGGCGCTG CAAGGCCC TGGGGCCCAC chr16:30913648-30913728 14 2.30e-03 gcgccgccgT GGAGGCCT TGCTGGCCGC chr10:116581864-11658194 20 2.30e-03 GTGGAGGCGG TAAGGCCG CGGGCTGCGG chr2:74405711-74405791 17 2.30e-03 TCAGGTCCGG GGAGGCCT CCCCCACAAC chr7:129251800-129251880 3 2.30e-03 ga ttcggccc gcctcgggcg chr8:91658076-91658156 60 2.54e-03 CTCCGCATGC CTCGGCCC AGCGCGGGCC chr17:47592772-47592852 41 3.00e-03 GAGGCATTCG GCAGGCCT GGCCTGGAGT chr21:43374012-43374092 31 3.14e-03 TGGGAAGTTC CTGGGCCG CTGCGGGCCG chr3:193859578-193859658 20 3.14e-03 GCTGGGGAAA CTGGGCCG AGGCCAGGGC chr16:447244-447324 21 3.29e-03 GGGGCTGCGC Tgcggccc gcgggccccg chr3:47205107-47205187 55 3.29e-03 GCGGGCCTGC TGCGGCCC CGGCCAAGCG chr2:98612156-98612236 6 3.93e-03 TCCGG CGCGGCCC TTCTCGGCGA chr2:61921716-61921796 36 3.93e-03 AGCGGCACGG CGCGGCCC TGTCCCCCAA chr1:9294911-9294991 12 3.93e-03 CGCCTTCCCC TGCGGCCG CCGCGGGCTC chr10:11784520-11784600 5 3.93e-03 CACC TGCGGCCG GCCAGGCAGC chr19:4123900-4123980 64 3.93e-03 Agcccggggc tgcggccg cggcccagg chr20:33413228-33413308 52 3.93e-03 CTCACCTGAg cgcggccc cggccctccc chr15:45459098-45459178 32 3.93e-03 GCGCGGCCCC CGCGGCCC GTCCCGCCAG chr5:162887049-162887129 26 4.60e-03 CCCTCCCGGC CGCGGCCG CACCAGGCGG chr1:117909652-117909732 72 4.60e-03 AGGAAGGAGA CGCGGCCG A chr16:4674883-4674963 41 5.32e-03 CCGCTCCCGT TCCGGCCC TGGCCCCTCT chr12:27933217-27933297 33 5.32e-03 GCTGCCGCCC CGGGGCCC CCAGCCATGT chr1:53192255-53192335 37 5.32e-03 CGGGCTCCGG TCCGGCCC GCCGCCGCAC chr10:13389403-13389483 58 5.32e-03 ggcggcagct cggggccc cggccgggcc chr7:72936244-72936324 51 5.32e-03 TGGCGGCTGC TGGGGCCG GCCCCGCGGC chr7:6746216-6746296 65 6.45e-03 CCTGCGGAGC CGGGGCCG GGCCGTCG chr15:40226441-40226521 36 6.45e-03 ACCACGAGCT ACAGGCCC TGGAGGCCAT chr7:73588795-73588875 28 6.45e-03 CCGGCGGAGT CGGGGCCG TCAGGGTGGC chr1:23670380-23670460 11 6.45e-03 CTTCGCGGGA TCCGGCCG CATGGAGCAG chr7:148396167-148396247 13 6.45e-03 gcggcgcagg cccggccc cgagccgcgg chr7:56032434-56032514 46 6.45e-03 CGGTCTCCGC CCCGGCCC TGTCCCCAGC chr1:46663960-46664040 71 7.08e-03 cgggccccgc tcgggccc cg chr20:56884845-56884925 27 7.08e-03 CTGGCAGCGG ACAGGCCG GACCTACGGC chr5:180688700-180688780 57 7.08e-03 CCGTGAGCCG TCGGGCCC CAGCTCCACG chr8:48173319-48173399 55 7.71e-03 CTTCCGGGCT CCGGGCCC GACTAGGCCA chr18:48494494-48494574 58 8.50e-03 CTCGATCAGG CACGGCCC GGCGCTGGGG chr1:247495328-247495408 12 8.50e-03 ggcctggccg ccgggccg ggggcTTTGT chr6:157100637-157100717 3 8.50e-03 CC GGCGGCCT CGCCGCGCCG chr22:22862841-22862921 12 8.74e-03 GCTGTATTGC AAAGGCCG CTCCGGCAGC chr1:41707529-41707609 12 8.74e-03 GCCGGGCTGA CACGGCCG AGAAAGGGCC chr14:24899230-24899310 43 9.11e-03 CGGGCAAAGC GGGGGCCT GGCGGGCGCT chr3:196729862-196729942 13 9.11e-03 CGCGTCCCCA GGGGGCCT CGCGGAcggg -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CBVGGCCT MEME-1 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr11:11863737-11863817 3.9e-06 61_[+1]_11 chr11:118661445-11866152 3.9e-06 28_[+1]_44 chr3:45731069-45731149 1.7e-05 70_[+1]_2 chr2:176045835-176045915 1.7e-05 32_[+1]_40 chr12:74931748-74931828 1.7e-05 58_[+1]_14 chr19:18942914-18942994 1.7e-05 34_[+1]_38 chr3:47844801-47844881 1.7e-05 55_[+1]_17 chr19:48894041-48894121 1.7e-05 24_[+1]_48 chr11:16760369-16760449 3e-05 49_[+1]_23 chr9:114245580-114245660 3e-05 9_[+1]_63 chr1:173990986-173991066 3e-05 38_[+1]_34 chr11:17297866-17297946 7.3e-05 [+1]_72 chr20:30311150-30311230 7.3e-05 18_[+1]_54 chr6:126111572-126111652 7.3e-05 29_[+1]_43 chr1:42922398-42922478 7.3e-05 47_[+1]_25 chr14:69864749-69864829 7.3e-05 17_[+1]_55 chr1:6685379-6685459 7.3e-05 32_[+1]_40 chr15:65477469-65477549 7.3e-05 27_[+1]_45 chr4:39978603-39978683 7.3e-05 32_[+1]_40 chr14:69618548-69618628 7.3e-05 6_[+1]_66 chr19:5293126-5293206 7.3e-05 56_[+1]_16 chr5:141488656-141488736 8.6e-05 10_[+1]_62 chr6:20403537-20403617 0.00013 51_[+1]_21 chr17:44344101-44344181 0.00013 21_[+1]_51 chr14:105767050-10576713 0.00013 12_[+1]_60 chr16:4321931-4322011 0.00013 48_[+1]_24 chr19:14229143-14229223 0.00013 44_[+1]_28 chr6:52442113-52442193 0.00013 42_[+1]_30 chr17:26220080-26220160 0.00013 33_[+1]_39 chrX:56590086-56590166 0.00013 36_[+1]_36 chr13:111358351-11135843 0.00013 58_[+1]_14 chr7:148396374-148396454 0.00013 [+1]_72 chr19:38146096-38146176 0.00013 49_[+1]_23 chr19:4969296-4969376 0.00013 51_[+1]_21 chr15:57025396-57025476 0.00013 7_[+1]_65 chr5:137089792-137089872 0.00013 33_[+1]_39 chr12:53846281-53846361 0.00016 71_[+1]_1 chr15:65425505-65425585 0.00016 17_[+1]_55 chr5:139486990-139487070 0.00016 63_[+1]_9 chr20:32951482-32951562 0.00016 28_[+1]_44 chr3:51428901-51428981 0.00016 45_[+1]_27 chr11:66247601-66247681 0.00021 7_[+1]_65 chr4:103422609-103422689 0.00021 22_[+1]_50 chr19:47249409-47249489 0.00021 11_[+1]_61 chr5:176561157-176561237 0.00021 67_[+1]_5 chr19:16738435-16738515 0.00021 41_[+1]_31 chr7:73097539-73097619 0.00022 22_[+1]_50 chr20:56099786-56099866 0.00022 36_[+1]_36 chrX:54070568-54070648 0.00022 17_[+1]_55 chr1:22778803-22778883 0.00022 70_[+1]_2 chr3:9439543-9439623 0.00022 34_[+1]_38 chr12:54389534-54389614 0.00026 33_[+1]_39 chr7:156931144-156931224 0.00026 3_[+1]_69 chr5:177659591-177659671 0.00026 15_[+1]_57 chr21:34775882-34775962 0.00026 51_[+1]_21 chrX:118709012-118709092 0.00026 49_[+1]_23 chr17:61851750-61851830 0.00026 47_[+1]_25 chr6:158244290-158244370 0.00026 10_[+1]_62 chr18:72264573-72264653 0.00026 53_[+1]_19 chr11:65292727-65292807 0.00026 43_[+1]_29 chr4:699746-699826 0.0003 65_[+1]_7 chr5:32312679-32312759 0.0003 37_[+1]_35 chr12:112546346-11254642 0.0003 29_[+1]_43 chr10:94051119-94051199 0.0003 37_[+1]_35 chr1:197744073-197744153 0.0003 10_[+1]_62 chr16:57279190-57279270 0.00045 5_[+1]_67 chr8:61429955-61430035 0.00045 28_[+1]_44 chr8:97657475-97657555 0.00045 4_[+1]_68 chr5:176433509-176433589 0.00045 20_[+1]_52 chr14:89029574-89029654 0.00045 30_[+1]_42 chr22:20067917-20067997 0.00045 35_[+1]_37 chr17:11924361-11924441 0.00045 13_[+1]_59 chr3:150321315-150321395 0.00045 47_[+1]_25 chr3:47204906-47204986 0.00045 1_[+1]_71 chr2:61404628-61404708 0.00045 7_[+1]_65 chr6:76311957-76312037 0.00045 42_[+1]_30 chr19:8070322-8070402 0.00045 9_[+1]_63 chr1:16010795-16010875 0.00045 27_[+1]_45 chr16:48278523-48278603 0.00045 44_[+1]_28 chr1:87170742-87170822 0.00045 29_[+1]_43 chr1:154193702-154193782 0.00045 12_[+1]_60 chr22:35653632-35653712 0.00045 43_[+1]_29 chr10:22629703-22629783 0.00045 59_[+1]_13 chr1:224621934-224622014 0.00045 19_[+1]_53 chr2:183902848-183902928 0.00045 32_[+1]_40 chr15:66586172-66586252 0.00045 16_[+1]_56 chr5:56247685-56247765 0.00045 17_[+1]_55 chr2:85198927-85199007 0.00045 29_[+1]_43 chr13:53024480-53024560 0.00045 15_[+1]_57 chr16:58034377-58034457 0.00045 18_[+1]_54 chr11:63606777-63606857 0.00045 14_[+1]_58 chr11:13690550-13690630 0.00049 49_[+1]_23 chr1:24970106-24970186 0.00049 57_[+1]_15 chr7:140372929-140373009 0.00067 33_[+1]_39 chr1:67519707-67519787 0.00067 17_[+1]_55 chr6:157098610-157098690 0.00067 68_[+1]_4 chr10:115614627-11561470 0.00067 37_[+1]_35 chr6:90062303-90062383 0.00067 4_[+1]_68 chr1:212003762-212003842 0.00067 7_[+1]_65 chr11:126152965-12615304 0.00067 6_[+1]_66 chr4:99182076-99182156 0.00067 21_[+1]_51 chr16:69345424-69345504 0.00067 53_[+1]_19 chr15:78730791-78730871 0.00067 39_[+1]_33 chr17:47439123-47439203 0.00067 1_[+1]_71 chr4:110355118-110355198 0.00067 66_[+1]_6 chr22:41698316-41698396 0.00067 29_[+1]_43 chr2:206950476-206950556 0.00067 14_[+1]_58 chr10:181803-181883 0.00067 [+1]_72 chr4:77135146-77135226 0.00083 28_[+1]_44 chr7:56032639-56032719 0.00083 40_[+1]_32 chr12:125051897-12505197 0.00083 59_[+1]_13 chr11:107992461-10799254 0.00083 52_[+1]_20 chr22:46068094-46068174 0.00083 28_[+1]_44 chr15:52860951-52861031 0.00083 49_[+1]_23 chr16:66864617-66864697 0.00083 67_[+1]_5 chr2:24346596-24346676 0.00083 53_[+1]_19 chr1:46767487-46767567 0.00083 67_[+1]_5 chr19:30206214-30206294 0.00083 38_[+1]_34 chr19:15442925-15443005 0.00083 29_[+1]_43 chr10:6131198-6131278 0.00083 51_[+1]_21 chr7:129252002-129252082 0.00083 [+1]_72 chr19:4065642-4065722 0.00083 2_[+1]_70 chrX:24168008-24168088 0.00083 50_[+1]_22 chr3:122233487-122233567 0.00093 1_[+1]_71 chr5:39202570-39202650 0.00093 32_[+1]_40 chr20:57617616-57617696 0.00093 32_[+1]_40 chr8:59572026-59572106 0.00093 65_[+1]_7 chr10:33247060-33247140 0.00093 49_[+1]_23 chr3:182698024-182698104 0.00093 12_[+1]_60 chr2:75873956-75874036 0.0011 19_[+1]_53 chr3:182511642-182511722 0.0011 47_[+1]_25 chr2:37423845-37423925 0.0011 50_[+1]_22 chr17:45266377-45266457 0.0011 38_[+1]_34 chr10:25012130-25012210 0.0011 44_[+1]_28 chr6:18264552-18264632 0.0011 31_[+1]_41 chr7:40173981-40174061 0.0011 3_[+1]_69 chr2:105946268-105946348 0.0011 38_[+1]_34 chr9:95896454-95896534 0.0011 71_[+1]_1 chr15:63797055-63797135 0.0011 25_[+1]_47 chr8:42995844-42995924 0.0011 7_[+1]_65 chr11:47788505-47788585 0.0011 65_[+1]_7 chr12:56651934-56652014 0.0011 11_[+1]_61 chr7:39989632-39989712 0.0011 32_[+1]_40 chr6:24495284-24495364 0.0011 43_[+1]_29 chr3:25705949-25706029 0.0011 65_[+1]_7 chr8:38239417-38239497 0.0011 24_[+1]_48 chr19:29703749-29703829 0.0013 65_[+1]_7 chr10:7830267-7830347 0.0013 60_[+1]_12 chr3:140661154-140661234 0.0013 16_[+1]_56 chr11:2422134-2422214 0.0013 47_[+1]_25 chr3:15247953-15248033 0.0013 9_[+1]_63 chr16:67927365-67927445 0.0013 39_[+1]_33 chr3:47845001-47845081 0.0013 58_[+1]_14 chr16:57514217-57514297 0.0013 36_[+1]_36 chr7:149194518-149194598 0.0013 2_[+1]_70 chr10:75910345-75910425 0.0015 37_[+1]_35 chr5:168006316-168006396 0.0015 59_[+1]_13 chr15:83478660-83478740 0.0015 24_[+1]_48 chr10:65281339-65281419 0.0015 31_[+1]_41 chr16:67596873-67596953 0.0016 70_[+1]_2 chr1:36621746-36621826 0.0016 21_[+1]_51 chr1:176175894-176175974 0.0016 36_[+1]_36 chr1:185125629-185125709 0.0016 62_[+1]_10 chr6:33756547-33756627 0.0016 64_[+1]_8 chr10:28822967-28823047 0.0016 4_[+1]_68 chrX:153744468-153744548 0.0017 12_[+1]_60 chr7:134001465-134001545 0.0019 10_[+1]_62 chr2:128145144-128145224 0.0019 52_[+1]_20 chr10:131908886-13190896 0.0019 62_[+1]_10 chr21:38445139-38445219 0.0019 37_[+1]_35 chr2:64246566-64246646 0.0019 64_[+1]_8 chr1:151299859-151299939 0.0019 20_[+1]_52 chr16:30905272-30905352 0.0019 64_[+1]_8 chr2:20550170-20550250 0.0021 40_[+1]_32 chr15:85291581-85291661 0.0021 51_[+1]_21 chr19:42746653-42746733 0.0021 58_[+1]_14 chr7:148959444-148959524 0.0021 39_[+1]_33 chr19:48996908-48996988 0.0021 [+1]_72 chr2:18741643-18741723 0.0021 29_[+1]_43 chr10:103454039-10345411 0.0021 19_[+1]_53 chr9:33817619-33817699 0.0021 60_[+1]_12 chr11:130786133-13078621 0.0023 13_[+1]_59 chr16:30913648-30913728 0.0023 13_[+1]_59 chr10:116581864-11658194 0.0023 19_[+1]_53 chr2:74405711-74405791 0.0023 16_[+1]_56 chr7:129251800-129251880 0.0023 2_[+1]_70 chr8:91658076-91658156 0.0025 59_[+1]_13 chr17:47592772-47592852 0.003 40_[+1]_32 chr21:43374012-43374092 0.0031 30_[+1]_42 chr3:193859578-193859658 0.0031 19_[+1]_53 chr16:447244-447324 0.0033 20_[+1]_52 chr3:47205107-47205187 0.0033 54_[+1]_18 chr2:98612156-98612236 0.0039 5_[+1]_67 chr2:61921716-61921796 0.0039 35_[+1]_37 chr1:9294911-9294991 0.0039 11_[+1]_61 chr10:11784520-11784600 0.0039 4_[+1]_68 chr19:4123900-4123980 0.0039 63_[+1]_9 chr20:33413228-33413308 0.0039 51_[+1]_21 chr15:45459098-45459178 0.0039 31_[+1]_41 chr5:162887049-162887129 0.0046 25_[+1]_47 chr1:117909652-117909732 0.0046 71_[+1]_1 chr16:4674883-4674963 0.0053 40_[+1]_32 chr12:27933217-27933297 0.0053 32_[+1]_40 chr1:53192255-53192335 0.0053 36_[+1]_36 chr10:13389403-13389483 0.0053 57_[+1]_15 chr7:72936244-72936324 0.0053 50_[+1]_22 chr7:6746216-6746296 0.0064 64_[+1]_8 chr15:40226441-40226521 0.0064 35_[+1]_37 chr7:73588795-73588875 0.0064 27_[+1]_45 chr1:23670380-23670460 0.0064 10_[+1]_62 chr7:148396167-148396247 0.0064 12_[+1]_60 chr7:56032434-56032514 0.0064 45_[+1]_27 chr1:46663960-46664040 0.0071 70_[+1]_2 chr20:56884845-56884925 0.0071 26_[+1]_46 chr5:180688700-180688780 0.0071 56_[+1]_16 chr8:48173319-48173399 0.0077 54_[+1]_18 chr18:48494494-48494574 0.0085 57_[+1]_15 chr1:247495328-247495408 0.0085 11_[+1]_61 chr6:157100637-157100717 0.0085 2_[+1]_70 chr22:22862841-22862921 0.0087 11_[+1]_61 chr1:41707529-41707609 0.0087 11_[+1]_61 chr14:24899230-24899310 0.0091 42_[+1]_30 chr3:196729862-196729942 0.0091 12_[+1]_60 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CBVGGCCT MEME-1 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF CBVGGCCT width=8 seqs=223 chr11:11863737-11863817 ( 62) TTAGGCCT 1 chr11:118661445-11866152 ( 29) TTAGGCCT 1 chr3:45731069-45731149 ( 71) CTAGGCCT 1 chr2:176045835-176045915 ( 33) CTAGGCCT 1 chr12:74931748-74931828 ( 59) CTAGGCCT 1 chr19:18942914-18942994 ( 35) CTAGGCCT 1 chr3:47844801-47844881 ( 56) CTAGGCCT 1 chr19:48894041-48894121 ( 25) CTAGGCCT 1 chr11:16760369-16760449 ( 50) TGAGGCCT 1 chr9:114245580-114245660 ( 10) TGAGGCCT 1 chr1:173990986-173991066 ( 39) TGAGGCCT 1 chr11:17297866-17297946 ( 1) CGAGGCCT 1 chr20:30311150-30311230 ( 19) CGAGGCCT 1 chr6:126111572-126111652 ( 30) CGAGGCCT 1 chr1:42922398-42922478 ( 48) CGAGGCCT 1 chr14:69864749-69864829 ( 18) CGAGGCCT 1 chr1:6685379-6685459 ( 33) CGAGGCCT 1 chr15:65477469-65477549 ( 28) CGAGGCCT 1 chr4:39978603-39978683 ( 33) CGAGGCCT 1 chr14:69618548-69618628 ( 7) CGAGGCCT 1 chr19:5293126-5293206 ( 57) CGAGGCCT 1 chr5:141488656-141488736 ( 11) TCAGGCCT 1 chr6:20403537-20403617 ( 52) CCAGGCCT 1 chr17:44344101-44344181 ( 22) CCAGGCCT 1 chr14:105767050-10576713 ( 13) CCAGGCCT 1 chr16:4321931-4322011 ( 49) CCAGGCCT 1 chr19:14229143-14229223 ( 45) CCAGGCCT 1 chr6:52442113-52442193 ( 43) CCAGGCCT 1 chr17:26220080-26220160 ( 34) CCAGGCCT 1 chrX:56590086-56590166 ( 37) CCAGGCCT 1 chr13:111358351-11135843 ( 59) CCAGGCCT 1 chr7:148396374-148396454 ( 1) CCAGGCCT 1 chr19:38146096-38146176 ( 50) CCAGGCCT 1 chr19:4969296-4969376 ( 52) CCAGGCCT 1 chr15:57025396-57025476 ( 8) CCAGGCCT 1 chr5:137089792-137089872 ( 34) TAAGGCCT 1 chr12:53846281-53846361 ( 72) CAAGGCCT 1 chr15:65425505-65425585 ( 18) TTCGGCCT 1 chr5:139486990-139487070 ( 64) TTCGGCCT 1 chr20:32951482-32951562 ( 29) TTCGGCCT 1 chr3:51428901-51428981 ( 46) CAAGGCCT 1 chr11:66247601-66247681 ( 8) CTCGGCCT 1 chr4:103422609-103422689 ( 23) CTCGGCCT 1 chr19:47249409-47249489 ( 12) CTCGGCCT 1 chr5:176561157-176561237 ( 68) CTCGGCCT 1 chr19:16738435-16738515 ( 42) CTCGGCCT 1 chr7:73097539-73097619 ( 23) TTGGGCCT 1 chr20:56099786-56099866 ( 37) TTGGGCCT 1 chrX:54070568-54070648 ( 18) TTGGGCCT 1 chr1:22778803-22778883 ( 71) TTGGGCCT 1 chr3:9439543-9439623 ( 35) TTGGGCCT 1 chr12:54389534-54389614 ( 34) CTGGGCCT 1 chr7:156931144-156931224 ( 4) CTGGGCCT 1 chr5:177659591-177659671 ( 16) CTGGGCCT 1 chr21:34775882-34775962 ( 52) CTGGGCCT 1 chrX:118709012-118709092 ( 50) CTGGGCCT 1 chr17:61851750-61851830 ( 48) CTGGGCCT 1 chr6:158244290-158244370 ( 11) CTGGGCCT 1 chr18:72264573-72264653 ( 54) CTGGGCCT 1 chr11:65292727-65292807 ( 44) CTGGGCCT 1 chr4:699746-699826 ( 66) TGCGGCCT 1 chr5:32312679-32312759 ( 38) TGCGGCCT 1 chr12:112546346-11254642 ( 30) TGCGGCCT 1 chr10:94051119-94051199 ( 38) TGCGGCCT 1 chr1:197744073-197744153 ( 11) TGCGGCCT 1 chr16:57279190-57279270 ( 6) AGAGGCCT 1 chr8:61429955-61430035 ( 29) CGCGGCCT 1 chr8:97657475-97657555 ( 5) CGCGGCCT 1 chr5:176433509-176433589 ( 21) AGAGGCCT 1 chr14:89029574-89029654 ( 31) CGCGGCCT 1 chr22:20067917-20067997 ( 36) CGCGGCCT 1 chr17:11924361-11924441 ( 14) CGCGGCCT 1 chr3:150321315-150321395 ( 48) CGCGGCCT 1 chr3:47204906-47204986 ( 2) CGCGGCCT 1 chr2:61404628-61404708 ( 8) CGCGGCCT 1 chr6:76311957-76312037 ( 43) AGAGGCCT 1 chr19:8070322-8070402 ( 10) CGCGGCCT 1 chr1:16010795-16010875 ( 28) CGCGGCCT 1 chr16:48278523-48278603 ( 45) CGCGGCCT 1 chr1:87170742-87170822 ( 30) AGAGGCCT 1 chr1:154193702-154193782 ( 13) CGCGGCCT 1 chr22:35653632-35653712 ( 44) CGCGGCCT 1 chr10:22629703-22629783 ( 60) AGAGGCCT 1 chr1:224621934-224622014 ( 20) AGAGGCCT 1 chr2:183902848-183902928 ( 33) CGCGGCCT 1 chr15:66586172-66586252 ( 17) CGCGGCCT 1 chr5:56247685-56247765 ( 18) CGCGGCCT 1 chr2:85198927-85199007 ( 30) CGCGGCCT 1 chr13:53024480-53024560 ( 16) AGAGGCCT 1 chr16:58034377-58034457 ( 19) CGCGGCCT 1 chr11:63606777-63606857 ( 15) CGCGGCCT 1 chr11:13690550-13690630 ( 50) TGGGGCCT 1 chr1:24970106-24970186 ( 58) TGGGGCCT 1 chr7:140372929-140373009 ( 34) TCCGGCCT 1 chr1:67519707-67519787 ( 18) CGGGGCCT 1 chr6:157098610-157098690 ( 69) CGGGGCCT 1 chr10:115614627-11561470 ( 38) TCCGGCCT 1 chr6:90062303-90062383 ( 5) TCCGGCCT 1 chr1:212003762-212003842 ( 8) CGGGGCCT 1 chr11:126152965-12615304 ( 7) CGGGGCCT 1 chr4:99182076-99182156 ( 22) TCCGGCCT 1 chr16:69345424-69345504 ( 54) CGGGGCCT 1 chr15:78730791-78730871 ( 40) CGGGGCCT 1 chr17:47439123-47439203 ( 2) TCCGGCCT 1 chr4:110355118-110355198 ( 67) CGGGGCCT 1 chr22:41698316-41698396 ( 30) CGGGGCCT 1 chr2:206950476-206950556 ( 15) CGGGGCCT 1 chr10:181803-181883 ( 1) CGGGGCCT 1 chr4:77135146-77135226 ( 29) CCCGGCCT 1 chr7:56032639-56032719 ( 41) CCCGGCCT 1 chr12:125051897-12505197 ( 60) CCCGGCCT 1 chr11:107992461-10799254 ( 53) TTAGGCCC 1 chr22:46068094-46068174 ( 29) CCCGGCCT 1 chr15:52860951-52861031 ( 50) CCCGGCCT 1 chr16:66864617-66864697 ( 68) TTAGGCCC 1 chr2:24346596-24346676 ( 54) CCCGGCCT 1 chr1:46767487-46767567 ( 68) CCCGGCCT 1 chr19:30206214-30206294 ( 39) CCCGGCCT 1 chr19:15442925-15443005 ( 30) CCCGGCCT 1 chr10:6131198-6131278 ( 52) TTAGGCCC 1 chr7:129252002-129252082 ( 1) CCCGGCCT 1 chr19:4065642-4065722 ( 3) CCCGGCCT 1 chrX:24168008-24168088 ( 51) TTAGGCCC 1 chr3:122233487-122233567 ( 2) CTAGGCCC 1 chr5:39202570-39202650 ( 33) TCGGGCCT 1 chr20:57617616-57617696 ( 33) CTAGGCCC 1 chr8:59572026-59572106 ( 66) CTAGGCCC 1 chr10:33247060-33247140 ( 50) TCGGGCCT 1 chr3:182698024-182698104 ( 13) CTAGGCCC 1 chr2:75873956-75874036 ( 20) CTAGGCCG 1 chr3:182511642-182511722 ( 48) CTAGGCCG 1 chr2:37423845-37423925 ( 51) CCGGGCCT 1 chr17:45266377-45266457 ( 39) CCGGGCCT 1 chr10:25012130-25012210 ( 45) CTAGGCCG 1 chr6:18264552-18264632 ( 32) CCGGGCCT 1 chr7:40173981-40174061 ( 4) TACGGCCT 1 chr2:105946268-105946348 ( 39) CCGGGCCT 1 chr9:95896454-95896534 ( 72) CCGGGCCT 1 chr15:63797055-63797135 ( 26) CCGGGCCT 1 chr8:42995844-42995924 ( 8) CTAGGCCG 1 chr11:47788505-47788585 ( 66) CTAGGCCG 1 chr12:56651934-56652014 ( 12) CTAGGCCG 1 chr7:39989632-39989712 ( 33) CTAGGCCG 1 chr6:24495284-24495364 ( 44) CCGGGCCT 1 chr3:25705949-25706029 ( 66) CCGGGCCT 1 chr8:38239417-38239497 ( 25) CTAGGCCG 1 chr19:29703749-29703829 ( 66) TGAGGCCC 1 chr10:7830267-7830347 ( 61) CAGGGCCT 1 chr3:140661154-140661234 ( 17) TGAGGCCC 1 chr11:2422134-2422214 ( 48) TGAGGCCC 1 chr3:15247953-15248033 ( 10) CAGGGCCT 1 chr16:67927365-67927445 ( 40) CAGGGCCT 1 chr3:47845001-47845081 ( 59) CAGGGCCT 1 chr16:57514217-57514297 ( 37) CAGGGCCT 1 chr7:149194518-149194598 ( 3) CAGGGCCT 1 chr10:75910345-75910425 ( 38) CGAGGCCC 1 chr5:168006316-168006396 ( 60) CGAGGCCC 1 chr15:83478660-83478740 ( 25) TGAGGCCG 1 chr10:65281339-65281419 ( 32) CGAGGCCC 1 chr16:67596873-67596953 ( 71) CGAGGCCG 1 chr1:36621746-36621826 ( 22) CGAGGCCG 1 chr1:176175894-176175974 ( 37) CGAGGCCG 1 chr1:185125629-185125709 ( 63) CGAGGCCG 1 chr6:33756547-33756627 ( 65) CGAGGCCG 1 chr10:28822967-28823047 ( 5) CGAGGCCG 1 chrX:153744468-153744548 ( 13) TCAGGCCC 1 chr7:134001465-134001545 ( 11) CCAGGCCC 1 chr2:128145144-128145224 ( 53) CCAGGCCC 1 chr10:131908886-13190896 ( 63) CCAGGCCC 1 chr21:38445139-38445219 ( 38) CCAGGCCC 1 chr2:64246566-64246646 ( 65) AGCGGCCT 1 chr1:151299859-151299939 ( 21) CCAGGCCC 1 chr16:30905272-30905352 ( 65) CCAGGCCC 1 chr2:20550170-20550250 ( 41) CCAGGCCG 1 chr15:85291581-85291661 ( 52) CCAGGCCG 1 chr19:42746653-42746733 ( 59) CCAGGCCG 1 chr7:148959444-148959524 ( 40) CCAGGCCG 1 chr19:48996908-48996988 ( 1) CCAGGCCG 1 chr2:18741643-18741723 ( 30) CCAGGCCG 1 chr10:103454039-10345411 ( 20) CCAGGCCG 1 chr9:33817619-33817699 ( 61) AGGGGCCT 1 chr11:130786133-13078621 ( 14) CAAGGCCC 1 chr16:30913648-30913728 ( 14) GGAGGCCT 1 chr10:116581864-11658194 ( 20) TAAGGCCG 1 chr2:74405711-74405791 ( 17) GGAGGCCT 1 chr7:129251800-129251880 ( 3) TTCGGCCC 1 chr8:91658076-91658156 ( 60) CTCGGCCC 1 chr17:47592772-47592852 ( 41) GCAGGCCT 1 chr21:43374012-43374092 ( 31) CTGGGCCG 1 chr3:193859578-193859658 ( 20) CTGGGCCG 1 chr16:447244-447324 ( 21) TGCGGCCC 1 chr3:47205107-47205187 ( 55) TGCGGCCC 1 chr2:98612156-98612236 ( 6) CGCGGCCC 1 chr2:61921716-61921796 ( 36) CGCGGCCC 1 chr1:9294911-9294991 ( 12) TGCGGCCG 1 chr10:11784520-11784600 ( 5) TGCGGCCG 1 chr19:4123900-4123980 ( 64) TGCGGCCG 1 chr20:33413228-33413308 ( 52) CGCGGCCC 1 chr15:45459098-45459178 ( 32) CGCGGCCC 1 chr5:162887049-162887129 ( 26) CGCGGCCG 1 chr1:117909652-117909732 ( 72) CGCGGCCG 1 chr16:4674883-4674963 ( 41) TCCGGCCC 1 chr12:27933217-27933297 ( 33) CGGGGCCC 1 chr1:53192255-53192335 ( 37) TCCGGCCC 1 chr10:13389403-13389483 ( 58) CGGGGCCC 1 chr7:72936244-72936324 ( 51) TGGGGCCG 1 chr7:6746216-6746296 ( 65) CGGGGCCG 1 chr15:40226441-40226521 ( 36) ACAGGCCC 1 chr7:73588795-73588875 ( 28) CGGGGCCG 1 chr1:23670380-23670460 ( 11) TCCGGCCG 1 chr7:148396167-148396247 ( 13) CCCGGCCC 1 chr7:56032434-56032514 ( 46) CCCGGCCC 1 chr1:46663960-46664040 ( 71) TCGGGCCC 1 chr20:56884845-56884925 ( 27) ACAGGCCG 1 chr5:180688700-180688780 ( 57) TCGGGCCC 1 chr8:48173319-48173399 ( 55) CCGGGCCC 1 chr18:48494494-48494574 ( 58) CACGGCCC 1 chr1:247495328-247495408 ( 12) CCGGGCCG 1 chr6:157100637-157100717 ( 3) GGCGGCCT 1 chr22:22862841-22862921 ( 12) AAAGGCCG 1 chr1:41707529-41707609 ( 12) CACGGCCG 1 chr14:24899230-24899310 ( 43) GGGGGCCT 1 chr3:196729862-196729942 ( 13) GGGGGCCT 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CBVGGCCT MEME-1 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 7.56606 E= 3.7e-061 -118 84 -382 102 -86 -37 12 96 182 -27 -60 -1444 -1444 -1444 139 -1444 -1444 -1444 139 -1444 -1444 139 -1444 -1444 -1444 139 -1444 -1444 -1444 -106 -116 249 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CBVGGCCT MEME-1 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 223 E= 3.7e-061 0.053812 0.686099 0.026906 0.233184 0.067265 0.295964 0.412556 0.224215 0.430493 0.318386 0.251121 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.183857 0.170404 0.645740 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CBVGGCCT MEME-1 regular expression -------------------------------------------------------------------------------- [CT][GCT][ACG]GGCCT -------------------------------------------------------------------------------- Time 5.13 secs. ******************************************************************************** ******************************************************************************** MOTIF TTTTCCBC MEME-2 width = 8 sites = 8 llr = 92 E-value = 2.2e+001 ******************************************************************************** -------------------------------------------------------------------------------- Motif TTTTCCBC MEME-2 Description -------------------------------------------------------------------------------- Simplified A :::::::: pos.-specific C ::::aa38 probability G ::::::31 matrix T aaaa::51 bits 3.1 **** 2.8 **** 2.5 **** 2.2 **** Relative 1.9 **** Entropy 1.6 **** (16.5 bits) 1.2 ****** 0.9 ****** 0.6 ******** 0.3 ******** 0.0 -------- Multilevel TTTTCCTC consensus C sequence G -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTTTCCBC MEME-2 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr3:45731069-45731149 46 1.13e-06 CATTTACCGG TTTTCCTC AGCCGGCGCG chr1:1093058-1093138 40 1.13e-06 GGAGACTGGG TTTTCCTC CCAGGGTTCT chr16:67596873-67596953 49 1.47e-06 GGCGACTCCA TTTTCCTT CCTTTGTCTG chr20:30311150-30311230 55 2.59e-06 TGAGACCACG TTTTCCTG GGGACAGGCC chr2:61404628-61404708 23 1.01e-05 CCTTTCCTTG TTTTCCGC CCAGTCCACG chr6:157100637-157100717 51 1.01e-05 TGCCGCGTAC TTTTCCCC GTCTTcccgc chr10:33247060-33247140 14 1.01e-05 GGCCCCTACC TTTTCCGC GCGGCGTCCG chr8:38239417-38239497 53 1.01e-05 CCGGGCTAGA TTTTCCCC GCGCCGGACG -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTTTCCBC MEME-2 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr3:45731069-45731149 1.1e-06 45_[+2]_27 chr1:1093058-1093138 1.1e-06 39_[+2]_33 chr16:67596873-67596953 1.5e-06 48_[+2]_24 chr20:30311150-30311230 2.6e-06 54_[+2]_18 chr2:61404628-61404708 1e-05 22_[+2]_50 chr6:157100637-157100717 1e-05 50_[+2]_22 chr10:33247060-33247140 1e-05 13_[+2]_59 chr8:38239417-38239497 1e-05 52_[+2]_20 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTTTCCBC MEME-2 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF TTTTCCBC width=8 seqs=8 chr3:45731069-45731149 ( 46) TTTTCCTC 1 chr1:1093058-1093138 ( 40) TTTTCCTC 1 chr16:67596873-67596953 ( 49) TTTTCCTT 1 chr20:30311150-30311230 ( 55) TTTTCCTG 1 chr2:61404628-61404708 ( 23) TTTTCCGC 1 chr6:157100637-157100717 ( 51) TTTTCCCC 1 chr10:33247060-33247140 ( 14) TTTTCCGC 1 chr8:38239417-38239497 ( 53) TTTTCCCC 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTTTCCBC MEME-2 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 11.8922 E= 2.2e+001 -965 -965 -965 312 -965 -965 -965 312 -965 -965 -965 312 -965 -965 -965 312 -965 138 -965 -965 -965 138 -965 -965 -965 -61 -60 212 -965 97 -160 12 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTTTCCBC MEME-2 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 8 E= 2.2e+001 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.250000 0.250000 0.500000 0.000000 0.750000 0.125000 0.125000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTTTCCBC MEME-2 regular expression -------------------------------------------------------------------------------- TTTTCC[TCG]C -------------------------------------------------------------------------------- Time 8.52 secs. ******************************************************************************** ******************************************************************************** MOTIF WTAATVTT MEME-3 width = 8 sites = 5 llr = 62 E-value = 2.2e+001 ******************************************************************************** -------------------------------------------------------------------------------- Motif WTAATVTT MEME-3 Description -------------------------------------------------------------------------------- Simplified A 62a8242: pos.-specific C :::2:4:: probability G :::::2:: matrix T 48::8:8a bits 3.1 * * 2.8 * * 2.5 ** * ** 2.2 *** * ** Relative 1.9 ***** ** Entropy 1.6 ***** ** (17.9 bits) 1.2 ***** ** 0.9 ***** ** 0.6 ******** 0.3 ******** 0.0 -------- Multilevel ATAATATT consensus TA CACA sequence G -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif WTAATVTT MEME-3 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr10:25012130-25012210 62 7.53e-08 GCAGGCTCGG TTAATATT CATGAGCGGC chr11:16760369-16760449 24 4.35e-07 GACGATGTAA ATAATAAT GGCGGAGTGG chr3:160282788-160282868 46 1.29e-06 CAGGCCCGAC ATAAACTT CCCGGCGCGC chrX:118709012-118709092 33 2.41e-06 CGGGTAGGGG AAAATGTT TGGGTCTGGC chr19:18943124-18943204 7 4.31e-06 CCGACT TTACTCTT CCTAGCCAGA -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif WTAATVTT MEME-3 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr10:25012130-25012210 7.5e-08 61_[+3]_11 chr11:16760369-16760449 4.3e-07 23_[+3]_49 chr3:160282788-160282868 1.3e-06 45_[+3]_27 chrX:118709012-118709092 2.4e-06 32_[+3]_40 chr19:18943124-18943204 4.3e-06 6_[+3]_66 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif WTAATVTT MEME-3 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF WTAATVTT width=8 seqs=5 chr10:25012130-25012210 ( 62) TTAATATT 1 chr11:16760369-16760449 ( 24) ATAATAAT 1 chr3:160282788-160282868 ( 46) ATAAACTT 1 chrX:118709012-118709092 ( 33) AAAATGTT 1 chr19:18943124-18943204 ( 7) TTACTCTT 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif WTAATVTT MEME-3 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 12.7769 E= 2.2e+001 230 -897 -897 179 71 -897 -897 279 304 -897 -897 -897 271 -93 -897 -897 71 -897 -897 279 171 6 -92 -897 71 -897 -897 279 -897 -897 -897 311 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif WTAATVTT MEME-3 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 5 E= 2.2e+001 0.600000 0.000000 0.000000 0.400000 0.200000 0.000000 0.000000 0.800000 1.000000 0.000000 0.000000 0.000000 0.800000 0.200000 0.000000 0.000000 0.200000 0.000000 0.000000 0.800000 0.400000 0.400000 0.200000 0.000000 0.200000 0.000000 0.000000 0.800000 0.000000 0.000000 0.000000 1.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif WTAATVTT MEME-3 regular expression -------------------------------------------------------------------------------- [AT][TA]A[AC][TA][ACG][TA]T -------------------------------------------------------------------------------- Time 11.93 secs. ******************************************************************************** ******************************************************************************** MOTIF TCWTTCWY MEME-4 width = 8 sites = 10 llr = 106 E-value = 9.2e+001 ******************************************************************************** -------------------------------------------------------------------------------- Motif TCWTTCWY MEME-4 Description -------------------------------------------------------------------------------- Simplified A :25:::4: pos.-specific C :8:::8:4 probability G :::3:2:: matrix T a:57a:66 bits 3.1 * * 2.8 * * 2.5 * * 2.2 * * * * Relative 1.9 * *** * Entropy 1.6 * *** ** (15.3 bits) 1.2 * *** ** 0.9 ***** ** 0.6 ******** 0.3 ******** 0.0 -------- Multilevel TCATTCTT consensus ATG GAC sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCWTTCWY MEME-4 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr6:157100637-157100717 33 6.99e-07 AGCCTGAGTT TCTTTCTT TGCCGCGTAC chr19:14229143-14229223 12 1.66e-06 GCCGCCGGCG TCATTCAT AAGGCCTGGC chr15:41233957-41234037 60 2.59e-06 CCCCCCGCGC TCTTTGTT ACAGCCCGAC chr2:206950476-206950556 3 5.14e-06 TT TCATTCTC CGCCCGGGGC chr21:38445139-38445219 73 5.89e-06 TGGAGACTTC TATTTCTC chr5:176074704-176074784 55 1.16e-05 AGAGGGAGAT TCAGTCTT TTGCTGGGGG chr2:128145144-128145224 66 1.16e-05 GGCCCGTCCC TCTTTCAC ATGAAgc chr12:53846281-53846361 25 1.16e-05 GCCAGGCCGG TCATTCAC GCGAGGCCCT chr5:39202570-39202650 49 1.64e-05 CTAGTGGCTT TAAGTCAT GGTCTTGGTT chr1:1093058-1093138 72 2.42e-05 GCAAAGCCTG TCTGTGTT C -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCWTTCWY MEME-4 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr6:157100637-157100717 7e-07 32_[+4]_40 chr19:14229143-14229223 1.7e-06 11_[+4]_61 chr15:41233957-41234037 2.6e-06 59_[+4]_13 chr2:206950476-206950556 5.1e-06 2_[+4]_70 chr21:38445139-38445219 5.9e-06 72_[+4] chr5:176074704-176074784 1.2e-05 54_[+4]_18 chr2:128145144-128145224 1.2e-05 65_[+4]_7 chr12:53846281-53846361 1.2e-05 24_[+4]_48 chr5:39202570-39202650 1.6e-05 48_[+4]_24 chr1:1093058-1093138 2.4e-05 71_[+4]_1 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCWTTCWY MEME-4 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF TCWTTCWY width=8 seqs=10 chr6:157100637-157100717 ( 33) TCTTTCTT 1 chr19:14229143-14229223 ( 12) TCATTCAT 1 chr15:41233957-41234037 ( 60) TCTTTGTT 1 chr2:206950476-206950556 ( 3) TCATTCTC 1 chr21:38445139-38445219 ( 73) TATTTCTC 1 chr5:176074704-176074784 ( 55) TCAGTCTT 1 chr2:128145144-128145224 ( 66) TCTTTCAC 1 chr12:53846281-53846361 ( 25) TCATTCAC 1 chr5:39202570-39202650 ( 49) TAAGTCAT 1 chr1:1093058-1093138 ( 72) TCTGTGTT 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCWTTCWY MEME-4 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 12.3073 E= 9.2e+001 -997 -997 -997 312 72 106 -997 -997 204 -997 -997 212 -997 -997 -34 260 -997 -997 -997 312 -997 106 -93 -997 171 -997 -997 238 -997 6 -997 238 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCWTTCWY MEME-4 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 10 E= 9.2e+001 0.000000 0.000000 0.000000 1.000000 0.200000 0.800000 0.000000 0.000000 0.500000 0.000000 0.000000 0.500000 0.000000 0.000000 0.300000 0.700000 0.000000 0.000000 0.000000 1.000000 0.000000 0.800000 0.200000 0.000000 0.400000 0.000000 0.000000 0.600000 0.000000 0.400000 0.000000 0.600000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCWTTCWY MEME-4 regular expression -------------------------------------------------------------------------------- T[CA][AT][TG]T[CG][TA][TC] -------------------------------------------------------------------------------- Time 15.28 secs. ******************************************************************************** ******************************************************************************** MOTIF TATKGTTG MEME-5 width = 8 sites = 2 llr = 27 E-value = 5.3e+003 ******************************************************************************** -------------------------------------------------------------------------------- Motif TATKGTTG MEME-5 Description -------------------------------------------------------------------------------- Simplified A :a:::::: pos.-specific C :::::::: probability G :::5a::a matrix T a:a5:aa: bits 3.1 *** ** 2.8 *** ** 2.5 *** ** 2.2 *** ** Relative 1.9 *** ** Entropy 1.6 *** ** (19.6 bits) 1.2 ******** 0.9 ******** 0.6 ******** 0.3 ******** 0.0 -------- Multilevel TATGGTTG consensus T sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TATKGTTG MEME-5 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr12:69633703-69633783 67 3.54e-07 CCTCGCTCCC TATTGTTG GCGGCA chr1:154193702-154193782 1 1.53e-06 . TATGGTTG GGTTCGCGGC -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TATKGTTG MEME-5 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr12:69633703-69633783 3.5e-07 66_[+5]_6 chr1:154193702-154193782 1.5e-06 [+5]_72 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TATKGTTG MEME-5 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF TATKGTTG width=8 seqs=2 chr12:69633703-69633783 ( 67) TATTGTTG 1 chr1:154193702-154193782 ( 1) TATGGTTG 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TATKGTTG MEME-5 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 13.1555 E= 5.3e+003 -765 -765 -765 311 303 -765 -765 -765 -765 -765 -765 311 -765 -765 39 211 -765 -765 139 -765 -765 -765 -765 311 -765 -765 -765 311 -765 -765 139 -765 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TATKGTTG MEME-5 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 2 E= 5.3e+003 0.000000 0.000000 0.000000 1.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.500000 0.500000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TATKGTTG MEME-5 regular expression -------------------------------------------------------------------------------- TAT[GT]GTTG -------------------------------------------------------------------------------- Time 18.63 secs. ******************************************************************************** ******************************************************************************** SUMMARY OF MOTIFS ******************************************************************************** -------------------------------------------------------------------------------- Combined block diagrams: non-overlapping sites with p-value < 0.0001 -------------------------------------------------------------------------------- SEQUENCE NAME COMBINED P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr10:181803-181883 2.23e-01 80 chr2:206950476-206950556 4.12e-04 2_[+4(5.14e-06)]_70 chrX:24168008-24168088 7.92e-01 80 chr19:4065642-4065722 8.15e-01 80 chr8:38239417-38239497 2.89e-04 52_[+2(1.01e-05)]_20 chr5:137688600-137688680 9.45e-01 80 chr11:63606777-63606857 7.24e-01 80 chr16:58034377-58034457 6.49e-01 80 chr22:41698316-41698396 8.04e-01 80 chr10:103454039-10345411 2.51e-01 80 chr3:182698024-182698104 6.50e-01 80 chr3:9439543-9439623 1.35e-01 80 chr15:45459098-45459178 7.33e-01 80 chr19:16738435-16738515 3.22e-02 80 chr19:5293126-5293206 2.45e-01 56_[+1(7.33e-05)]_16 chr15:57025396-57025476 1.55e-01 80 chr10:28822967-28823047 7.05e-01 80 chr6:33756547-33756627 5.60e-01 80 chr7:129251800-129251880 9.39e-01 80 chr16:30905272-30905352 5.04e-01 80 chr7:129252002-129252082 6.27e-01 80 chr14:31676674-31676754 9.39e-01 80 chr5:180688700-180688780 8.55e-01 80 chr5:36877486-36877566 2.62e-01 80 chr11:65292727-65292807 1.11e-02 80 chr13:53024480-53024560 7.09e-01 80 chr19:18943124-18943204 3.57e-04 6_[+3(4.31e-06)]_66 chr2:85198927-85199007 2.12e-01 80 chr10:6131198-6131278 6.91e-01 80 chr5:56247685-56247765 5.38e-01 80 chr14:69618548-69618628 1.59e-02 6_[+1(7.33e-05)]_66 chr3:25705949-25706029 2.41e-01 80 chr15:66586172-66586252 4.24e-01 80 chr5:141488656-141488736 1.77e-01 10_[+1(8.63e-05)]_62 chr7:72936244-72936324 9.90e-01 80 chr10:33247060-33247140 1.48e-03 13_[+2(1.01e-05)]_59 chr6:24495284-24495364 6.50e-01 80 chr2:18741643-18741723 8.64e-03 80 chr18:72264573-72264653 6.77e-03 80 chr7:39989632-39989712 4.81e-02 80 chr1:173990986-173991066 9.35e-02 38_[+1(3.00e-05)]_34 chr2:183902848-183902928 1.69e-01 80 chr19:48996908-48996988 4.48e-01 80 chr19:4969296-4969376 4.83e-01 80 chr12:69633703-69633783 2.97e-04 66_[+5(3.54e-07)]_6 chr1:224621934-224622014 9.34e-02 80 chr4:110355118-110355198 6.70e-01 80 chr1:185125629-185125709 8.38e-01 80 chr6:157100637-157100717 1.28e-06 32_[+4(6.99e-07)]_10_[+2(1.01e-05)]_\ 22 chr10:22629703-22629783 4.38e-02 80 chr7:56032434-56032514 3.99e-01 80 chr12:56651934-56652014 7.91e-01 80 chr1:176175894-176175974 8.00e-01 80 chr4:39978603-39978683 6.08e-02 32_[+1(7.33e-05)]_40 chr3:196729862-196729942 9.99e-01 80 chr1:197744073-197744153 8.90e-02 80 chr7:149194518-149194598 7.93e-01 80 chr19:38146096-38146176 1.71e-02 80 chr22:35653632-35653712 4.21e-01 80 chr7:148396167-148396247 7.40e-01 80 chr1:154193702-154193782 4.29e-03 [+5(1.53e-06)]_72 chr10:65281339-65281419 5.90e-01 80 chr7:148959444-148959524 8.48e-01 80 chr12:54412060-54412140 6.51e-01 80 chr7:148396374-148396454 4.02e-02 80 chr1:87170742-87170822 4.18e-01 80 chr1:151299859-151299939 5.74e-01 80 chr16:57514217-57514297 5.84e-03 80 chr10:94051119-94051199 1.31e-04 80 chr1:23670380-23670460 8.68e-01 80 chr16:48278523-48278603 4.16e-01 80 chr17:47439123-47439203 4.13e-01 80 chr6:158244290-158244370 4.70e-01 80 chr19:48894041-48894121 1.66e-02 24_[+1(1.70e-05)]_48 chr1:22778803-22778883 3.67e-03 80 chr11:47788505-47788585 7.96e-01 80 chr17:61851750-61851830 1.33e-01 80 chr9:114245580-114245660 1.26e-01 9_[+1(3.00e-05)]_63 chr13:111358351-11135843 4.32e-01 80 chr8:42995844-42995924 4.77e-02 80 chr2:64246566-64246646 9.22e-01 80 chr20:33413228-33413308 9.55e-01 80 chr15:63797055-63797135 7.42e-01 80 chr15:65477469-65477549 1.64e-01 27_[+1(7.33e-05)]_45 chr19:15442925-15443005 7.40e-01 80 chr15:78730791-78730871 2.03e-02 80 chr3:47844801-47844881 8.62e-02 55_[+1(1.70e-05)]_17 chr11:16760369-16760449 7.42e-06 23_[+3(4.35e-07)]_18_[+1(3.00e-05)]_\ 23 chr16:69345424-69345504 2.80e-01 80 chr3:51428901-51428981 3.69e-01 80 chr8:48173319-48173399 7.97e-01 80 chr3:47845001-47845081 2.24e-02 80 chr1:6685379-6685459 3.02e-01 32_[+1(7.33e-05)]_40 chr9:95896454-95896534 4.64e-02 80 chr21:38445139-38445219 1.22e-04 72_[+4(5.89e-06)] chr19:30206214-30206294 7.06e-01 80 chr19:4123900-4123980 9.79e-01 80 chr1:16010795-16010875 2.69e-01 80 chr16:67927365-67927445 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chr14:54907852-54907932 2.17e-01 80 chr5:162887049-162887129 2.36e-01 80 -------------------------------------------------------------------------------- ******************************************************************************** ******************************************************************************** Stopped because requested number of motifs (5) found. ******************************************************************************** CPU: c22n05.farnam.hpc.yale.internal ********************************************************************************