******************************************************************************** MEME - Motif discovery tool ******************************************************************************** MEME version 5.3.3 (Release date: Sun Feb 7 15:39:52 2021 -0800) For further information on how to interpret these results please access https://meme-suite.org/meme. To get a copy of the MEME Suite software please access https://meme-suite.org. ******************************************************************************** ******************************************************************************** REFERENCE ******************************************************************************** If you use this program in your research, please cite: Timothy L. Bailey and Charles Elkan, "Fitting a mixture model by expectation maximization to discover motifs in biopolymers", Proceedings of the Second International Conference on Intelligent Systems for Molecular Biology, pp. 28-36, AAAI Press, Menlo Park, California, 1994. ******************************************************************************** ******************************************************************************** TRAINING SET ******************************************************************************** PRIMARY SEQUENCES= ../result/final_prediction/K562/fasta/RankLinear0.6_40/ZEB2.fasta CONTROL SEQUENCES= --none-- ALPHABET= ACGT Sequence name Weight Length Sequence name Weight Length ------------- ------ ------ ------------- ------ ------ chr11:3278834-3278914 1.0000 80 chr12:48137965-48138045 1.0000 80 chr6:87923291-87923371 1.0000 80 chr17:27564534-27564614 1.0000 80 chr6:126264341-126264421 1.0000 80 chr10:75692212-75692292 1.0000 80 chr3:14014613-14014693 1.0000 80 chr20:51040993-51041073 1.0000 80 chr17:48571276-48571356 1.0000 80 chr3:119414443-119414523 1.0000 80 chr15:51892467-51892547 1.0000 80 chr8:144536449-144536529 1.0000 80 chr22:38003240-38003320 1.0000 80 chr1:1059142-1059222 1.0000 80 chr2:8641059-8641139 1.0000 80 chr2:7006508-7006588 1.0000 80 chr10:3797421-3797501 1.0000 80 chr22:19155952-19156032 1.0000 80 chr1:39860434-39860514 1.0000 80 chr14:31500902-31500982 1.0000 80 chr19:9969614-9969694 1.0000 80 chr3:197304683-197304763 1.0000 80 chr1:67628827-67628907 1.0000 80 chr2:80539532-80539612 1.0000 80 chr1:89990725-89990805 1.0000 80 chr19:18491276-18491356 1.0000 80 chr2:48512244-48512324 1.0000 80 chr11:93305495-93305575 1.0000 80 chr12:123235892-12323597 1.0000 80 chr16:87495162-87495242 1.0000 80 chr1:233760158-233760238 1.0000 80 chr19:54676824-54676904 1.0000 80 chr5:75698261-75698341 1.0000 80 chr19:45594979-45595059 1.0000 80 chr16:1543432-1543512 1.0000 80 chr10:79728991-79729071 1.0000 80 chr5:43197805-43197885 1.0000 80 chr15:91576458-91576538 1.0000 80 chr10:115614163-11561424 1.0000 80 chr4:54457816-54457896 1.0000 80 chr11:108211860-10821194 1.0000 80 chr16:71460637-71460717 1.0000 80 chrX:153602046-153602126 1.0000 80 chr6:119580378-119580458 1.0000 80 chr2:236353027-236353107 1.0000 80 chr2:109237747-109237827 1.0000 80 chr4:2956828-2956908 1.0000 80 chr22:47169896-47169976 1.0000 80 chr19:11320690-11320770 1.0000 80 chr3:137906238-137906318 1.0000 80 chr21:37525427-37525507 1.0000 80 chr1:1059342-1059422 1.0000 80 chr19:14328365-14328445 1.0000 80 chr6:41182711-41182791 1.0000 80 chr9:127894177-127894257 1.0000 80 chr12:133006557-13300663 1.0000 80 chr15:78857518-78857598 1.0000 80 chr6:158184610-158184690 1.0000 80 chr10:74036359-74036439 1.0000 80 chr3:45008362-45008442 1.0000 80 chr15:74683427-74683507 1.0000 80 chr11:46638885-46638965 1.0000 80 chr2:171319278-171319358 1.0000 80 chr2:27184793-27184873 1.0000 80 chr7:127228953-127229033 1.0000 80 chr1:207919904-207919984 1.0000 80 chr11:33342671-33342751 1.0000 80 chr1:22587458-22587538 1.0000 80 chr10:61895010-61895090 1.0000 80 chr19:42429554-42429634 1.0000 80 chr9:116327691-116327771 1.0000 80 chr16:90098699-90098779 1.0000 80 chr11:118586753-11858683 1.0000 80 chr4:186240032-186240112 1.0000 80 chr1:202452648-202452728 1.0000 80 chr1:27189399-27189479 1.0000 80 chr16:1347051-1347131 1.0000 80 chr1:160991101-160991181 1.0000 80 chr1:27286869-27286949 1.0000 80 chr19:45057128-45057208 1.0000 80 chr9:138863950-138864030 1.0000 80 chr1:209979407-209979487 1.0000 80 chr19:39900163-39900243 1.0000 80 chr6:136871667-136871747 1.0000 80 chr6:5231066-5231146 1.0000 80 chr6:106760941-106761021 1.0000 80 chr1:168414959-168415039 1.0000 80 chr5:82265207-82265287 1.0000 80 chr16:11188054-11188134 1.0000 80 chr14:100017783-10001786 1.0000 80 chr2:11893772-11893852 1.0000 80 chr8:80766287-80766367 1.0000 80 chr13:37574769-37574849 1.0000 80 chr16:84173162-84173242 1.0000 80 chr16:9144511-9144591 1.0000 80 chr9:96974532-96974612 1.0000 80 chr2:12318566-12318646 1.0000 80 chr17:76356860-76356940 1.0000 80 chr12:123210726-12321080 1.0000 80 chr16:2193559-2193639 1.0000 80 chr1:15364802-15364882 1.0000 80 chr6:166795483-166795563 1.0000 80 chr1:27995619-27995699 1.0000 80 chr12:93963858-93963938 1.0000 80 chr11:16381088-16381168 1.0000 80 chr8:135725184-135725264 1.0000 80 chr17:45352820-45352900 1.0000 80 chr7:133886501-133886581 1.0000 80 chr11:10604355-10604435 1.0000 80 chr1:26109406-26109486 1.0000 80 chr17:38804171-38804251 1.0000 80 chr1:165812122-165812202 1.0000 80 chr2:103281019-103281099 1.0000 80 chr17:56818530-56818610 1.0000 80 chr6:109509244-109509324 1.0000 80 chr8:145277514-145277594 1.0000 80 chr19:41129876-41129956 1.0000 80 chr7:120778429-120778509 1.0000 80 chr3:43496824-43496904 1.0000 80 chr10:74021490-74021570 1.0000 80 chr3:46534570-46534650 1.0000 80 chr20:48629239-48629319 1.0000 80 chr22:21195375-21195455 1.0000 80 chr21:45303933-45304013 1.0000 80 chr6:29813284-29813364 1.0000 80 chr12:4647732-4647812 1.0000 80 chr6:28448064-28448144 1.0000 80 chr3:47523325-47523405 1.0000 80 chr2:70312485-70312565 1.0000 80 chr1:201894422-201894502 1.0000 80 chr17:76850332-76850412 1.0000 80 chr15:63688019-63688099 1.0000 80 chr6:3348241-3348321 1.0000 80 chr17:16302084-16302164 1.0000 80 chr17:34901352-34901432 1.0000 80 chr19:48151704-48151784 1.0000 80 chr2:15698279-15698359 1.0000 80 chr7:135667188-135667268 1.0000 80 chr17:8340065-8340145 1.0000 80 chr5:149489646-149489726 1.0000 80 chr6:157849965-157850045 1.0000 80 chr22:40451713-40451793 1.0000 80 chr6:117857561-117857641 1.0000 80 chr1:24741990-24742070 1.0000 80 chr6:135327832-135327912 1.0000 80 chr7:137652116-137652196 1.0000 80 chr11:123613252-12361333 1.0000 80 chr19:50637549-50637629 1.0000 80 chr6:28459522-28459602 1.0000 80 chr11:73495430-73495510 1.0000 80 chr16:89209032-89209112 1.0000 80 chr20:44997134-44997214 1.0000 80 chr7:129076316-129076396 1.0000 80 chr2:175075697-175075777 1.0000 80 chr5:138088737-138088817 1.0000 80 chr5:43067062-43067142 1.0000 80 chr1:201140085-201140165 1.0000 80 chr10:3852423-3852503 1.0000 80 chr7:140188215-140188295 1.0000 80 chr19:39174325-39174405 1.0000 80 chr16:85644517-85644597 1.0000 80 chr14:31713297-31713377 1.0000 80 chr3:99536510-99536590 1.0000 80 chr5:159087579-159087659 1.0000 80 chr20:49347826-49347906 1.0000 80 chr1:26595539-26595619 1.0000 80 chr11:118482002-11848208 1.0000 80 chrX:135213383-135213463 1.0000 80 chr11:118801020-11880110 1.0000 80 chr8:1326582-1326662 1.0000 80 chr15:66263566-66263646 1.0000 80 chr4:38623027-38623107 1.0000 80 chr7:72299827-72299907 1.0000 80 chr15:65545164-65545244 1.0000 80 chr5:140090597-140090677 1.0000 80 chr8:131012378-131012458 1.0000 80 chr16:12707633-12707713 1.0000 80 chr21:37630186-37630266 1.0000 80 chr10:135203779-13520385 1.0000 80 chr17:38673229-38673309 1.0000 80 chr8:128872135-128872215 1.0000 80 chr1:154285576-154285656 1.0000 80 chr11:71159292-71159372 1.0000 80 chr2:18739904-18739984 1.0000 80 chr1:31944529-31944609 1.0000 80 chr6:138290124-138290204 1.0000 80 chr7:73866808-73866888 1.0000 80 chr3:101350400-101350480 1.0000 80 chr1:59351054-59351134 1.0000 80 chr14:58894019-58894099 1.0000 80 chr10:63741416-63741496 1.0000 80 chr22:45127096-45127176 1.0000 80 chr5:180600595-180600675 1.0000 80 chr5:139548111-139548191 1.0000 80 chr3:195443017-195443097 1.0000 80 chr21:45277521-45277601 1.0000 80 chr3:45922728-45922808 1.0000 80 chr6:28047834-28047914 1.0000 80 chr16:9167027-9167107 1.0000 80 chr16:81069189-81069269 1.0000 80 chr6:27636482-27636562 1.0000 80 chr20:382716-382796 1.0000 80 chr19:909381-909461 1.0000 80 chr19:41172421-41172501 1.0000 80 chr12:94494120-94494200 1.0000 80 chr1:85187678-85187758 1.0000 80 chr9:130841362-130841442 1.0000 80 chr20:62446930-62447010 1.0000 80 chr11:118901449-11890152 1.0000 80 chr1:184775634-184775714 1.0000 80 chr11:3829344-3829424 1.0000 80 chrX:71792811-71792891 1.0000 80 chr12:118558523-11855860 1.0000 80 chr10:29238062-29238142 1.0000 80 chr16:4304190-4304270 1.0000 80 chr6:28889981-28890061 1.0000 80 chr8:129440620-129440700 1.0000 80 chr4:110651045-110651125 1.0000 80 chr18:8883068-8883148 1.0000 80 chr10:35703440-35703520 1.0000 80 chrX:9319964-9320044 1.0000 80 chr20:43665024-43665104 1.0000 80 chr8:96224824-96224904 1.0000 80 chr6:10348175-10348255 1.0000 80 chr9:135854199-135854279 1.0000 80 chr5:149088704-149088784 1.0000 80 chr17:900249-900329 1.0000 80 chr3:45133898-45133978 1.0000 80 chr13:46949046-46949126 1.0000 80 chr18:33039027-33039107 1.0000 80 chr1:3773891-3773971 1.0000 80 chr1:100820668-100820748 1.0000 80 chr3:156827459-156827539 1.0000 80 chr17:27621394-27621474 1.0000 80 chr16:11295808-11295888 1.0000 80 chr14:69658230-69658310 1.0000 80 chr10:50746791-50746871 1.0000 80 chr6:34294991-34295071 1.0000 80 chr6:13864177-13864257 1.0000 80 chr15:90756903-90756983 1.0000 80 chr7:149388116-149388196 1.0000 80 chr6:43905205-43905285 1.0000 80 chr16:12706615-12706695 1.0000 80 chr6:161736529-161736609 1.0000 80 chr17:76134096-76134176 1.0000 80 chr2:20630833-20630913 1.0000 80 chr1:52088302-52088382 1.0000 80 chr2:68518540-68518620 1.0000 80 chr4:40310331-40310411 1.0000 80 chr20:48675986-48676066 1.0000 80 ******************************************************************************** ******************************************************************************** COMMAND LINE SUMMARY ******************************************************************************** This information can also be useful in the event you wish to report a problem with the MEME software. command: meme -oc ../result/final_prediction/K562/inference_raw/MEME/RankLinear0.6_40_ZEB2/ -dna -nmotifs 5 -w 8 -maxsize 250000 -nostatus ../result/final_prediction/K562/fasta/RankLinear0.6_40/ZEB2.fasta model: mod= zoops nmotifs= 5 evt= inf objective function: em= E-value of product of p-values starts= E-value of product of p-values strands: + width: minw= 8 maxw= 8 nsites: minsites= 2 maxsites= 250 wnsites= 0.8 theta: spmap= uni spfuzz= 0.5 em: prior= dirichlet b= 0.01 maxiter= 50 distance= 1e-05 trim: wg= 11 ws= 1 endgaps= yes data: n= 20000 N= 250 sample: seed= 0 hsfrac= 0 searchsize= 20000 norand= no csites= 1000 Letter frequencies in dataset: A 0.238 C 0.258 G 0.266 T 0.237 Background letter frequencies (from file dataset with add-one prior applied): A 0.238 C 0.258 G 0.266 T 0.237 Background model order: 0 ******************************************************************************** ******************************************************************************** MOTIF CAGGTGAB MEME-1 width = 8 sites = 129 llr = 942 E-value = 8.2e-074 ******************************************************************************** -------------------------------------------------------------------------------- Motif CAGGTGAB MEME-1 Description -------------------------------------------------------------------------------- Simplified A :a::1351 pos.-specific C a:::::12 probability G ::aa:724 matrix T ::::9:23 bits 2.1 * 1.9 *** 1.7 ***** 1.5 ***** Relative 1.2 ***** Entropy 1.0 ***** (10.5 bits) 0.8 ****** 0.6 ****** 0.4 ******* 0.2 ******* 0.0 -------- Multilevel CAGGTGAG consensus ATT sequence C -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CAGGTGAB MEME-1 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr4:40310331-40310411 12 1.73e-05 ggcccaacgg caggtgag cagcagagtc chr10:50746791-50746871 8 1.73e-05 GCCGCCT CAGGTGAG CGCTCCTTGG chr9:135854199-135854279 27 1.73e-05 CAGCTCCGGA CAGGTGAG TGCTGGAGGA chr7:73866808-73866888 20 1.73e-05 cacacaggtc caggtgag tcagtcggtt chr11:118801020-11880110 36 1.73e-05 AATGGAGCGC CAGGTGAG GCACCACCCA chr10:3852423-3852503 60 1.73e-05 AATGCAGTCA CAGGTGAG ACAACCTTTG chr6:135327832-135327912 49 1.73e-05 AGGGGAGTGA CAGGTGAG TGAGGAGATA chr16:9144511-9144591 43 1.73e-05 CAGGTGAGCT CAGGTGAG CGAGGGGATA chr14:100017783-10001786 68 1.73e-05 ggtgggtgtg caggtgag tacgt chr19:39900163-39900243 48 1.73e-05 AGGGTGGGAC CAGGTGAG GTCACCAGAT chr19:45057128-45057208 32 1.73e-05 gggggacagt caggtgag ttatatctag chr1:27286869-27286949 39 1.73e-05 ACCTGGGGCG CAGGTGAG CGTCTCGCGG chr16:90098699-90098779 55 1.73e-05 CAGGTATGTA CAGGTGAG GAGGTGTGGT chr10:74036359-74036439 11 1.73e-05 TGCACACACA CAGGTGAG GGAAGGAGTG chr19:14328365-14328445 18 1.73e-05 CTGCGGCCGC CAGGTGAG GGGGCCCCGC chr22:38003240-38003320 17 1.73e-05 GCAATGGACC CAGGTGAG TCGGGGACCA chr22:21195375-21195455 26 3.28e-05 ctccttatct caggtgat acgcccacct chr1:202452648-202452728 39 3.28e-05 caggtcagag caggtgat agaggctagg chr8:144536449-144536529 45 3.28e-05 cttctgacct caggtgat ctgcccacct chr16:11295808-11295888 36 4.96e-05 GTTCAGCGGC CAGGTGAC GGACACATGG chr3:195443017-195443097 57 4.96e-05 cagattagag caggtgac tgggggtgac chr1:31944529-31944609 39 4.96e-05 caagatggag caggtgac caggggtgac chr5:140090597-140090677 11 4.96e-05 AGTTGTGGAC CAGGTGAC TGCTGAGAAG chr6:166795483-166795563 56 4.96e-05 TGGACGGCCG CAGGTGAC CGGCGACCCA chr16:11188054-11188134 24 4.96e-05 GTGTCACCTT CAGGTGAC CAAAGATGAA chr16:1347051-1347131 48 4.96e-05 cagggcagag caggtgac agggtgactc chr2:236353027-236353107 62 4.96e-05 tcagtcaaag caggtgac cgggatgagt chr15:91576458-91576538 23 4.96e-05 CGTACTGCTG CAGGTGAC CCAGGTACTG chr2:80539532-80539612 38 4.96e-05 caggtcaaag caggtgac cagaatgagt chr2:8641059-8641139 67 4.96e-05 CCAGGTAATG CAGGTGAC GCACAC chr3:14014613-14014693 7 4.96e-05 atggaa caggtgac taaaggtgac chr6:87923291-87923371 65 4.96e-05 tcaggtaaag caggtgac cgggatga chr17:38673229-38673309 70 6.51e-05 TTTCTCTTTC CAGGTAAG TAT chr6:109509244-109509324 26 6.51e-05 GCTTCTGTTG CAGGTAAG AGTGATACTG chr19:54676824-54676904 35 6.51e-05 GACACTGCCC CAGGTAAG GGAGGGGCCA chr12:48137965-48138045 39 6.51e-05 CACCTGAGCT CAGGTAAG GCACCTGGGA chr6:161736529-161736609 34 1.12e-04 cagggtgaag caggtaat cggaatgagt chr14:69658230-69658310 50 1.12e-04 GAGCCCGCTG CAGGTGTG CGGCCCAGTC chr18:8883068-8883148 50 1.12e-04 gagcaggtag caggtaat ctgaataagt chr8:129440620-129440700 67 1.12e-04 CTGAGTCCTC CAGGTAAT GGCAAA chr12:118558523-11855860 21 1.12e-04 aggatctgtt caggtgtg gttaccttct chr10:63741416-63741496 44 1.12e-04 CTTACCTGTT CAGGTGTG TGAGATCTTC chr3:101350400-101350480 32 1.12e-04 CCTGTAATAC CAGgtaat acctgtaaca chr14:31713297-31713377 50 1.12e-04 gagcaggtag caggtaat cggaatgagt chr11:73495430-73495510 41 1.12e-04 gctgagatta caggtgtg agccacagca chr20:48629239-48629319 60 1.12e-04 AGCAGAAGGT CAGGTGAA TCAACGATAA chr8:145277514-145277594 22 1.12e-04 GGTGCTGGCA CAGGTGTG GAGGAAGGTA chr11:10604355-10604435 4 1.12e-04 agc caggtgtg gtggcacaca chr1:15364802-15364882 27 1.12e-04 GCGCTGTTAC CAGGTAAT CATCCTGGCA chr8:80766287-80766367 37 1.12e-04 GTCACAACAA CAGGTGTG GCTGAGTGAA chr2:11893772-11893852 21 1.12e-04 TCTTTTGTCA CAGGTAAT TCATCACCCT chr5:82265207-82265287 55 1.12e-04 cagggcagag caggtaat tggaatgagt chr9:138863950-138864030 50 1.12e-04 CCAGGCAATC CAGGTGTG GCGGTGTCCC chr1:22587458-22587538 15 1.12e-04 CGTgtacgtg caggtgtg cggcaagtgt chr2:27184793-27184873 42 1.12e-04 GAAGGAATGG CAGGTGTG TCCAGGTTAC chr6:41182711-41182791 57 1.12e-04 taggtcagag caggtgaa caggatgagt chr1:67628827-67628907 46 1.12e-04 TGTATGTggc caggtgtg gtgactcatg chr3:197304683-197304763 41 1.12e-04 TTATCTCCTC CAGGTAAT GTGTCTTCAG chr5:149088704-149088784 18 1.27e-04 AATTTTCTTA CAGGTGTT TGTTGAGTGA chr1:201140085-201140165 18 1.27e-04 GCCGGGCCAG CAGGTGTT ACCTGAGTAA chr7:120778429-120778509 27 1.27e-04 aagcaaacac caggtgtt tttggcggca chr20:382716-382796 48 1.42e-04 tggttggctg caggtaac tgacattgca chr15:63688019-63688099 5 1.42e-04 ggaa caggtaac caaaggtgac chr12:123210726-12321080 61 1.42e-04 TACTCTTCCC CAGGTAAC TGAGGGGCGG chr10:29238062-29238142 49 1.62e-04 gcctgttgta caggtggg gaagcacaag chr20:62446930-62447010 25 1.62e-04 gcagtgggtg caggtggg cacaggtgca chr1:154285576-154285656 12 1.62e-04 GTCATCAGAG CAGGTGGG ACGTGCATGT chr1:27189399-27189479 28 1.62e-04 GGTGCCAGTG CAGGTGGG GCCCACGCCC chr12:123235892-12323597 72 1.78e-04 agacccttta caggtgtc g chr6:10348175-10348255 53 2.25e-04 AGAGACTGCA CAGGTGGT GACGGCAGTA chr19:909381-909461 37 2.25e-04 ACACAGCTGG CAGGTAAA CACCCAGAGA chr20:44997134-44997214 7 2.25e-04 CAGTCC CAGGTAAA TGACTCATTC chr2:15698279-15698359 68 2.25e-04 aagtggagct caggtggt aatgc chr6:28448064-28448144 15 2.25e-04 GCTTCAGACC CAGGTAAA CCTGCAGCTA chr21:45303933-45304013 39 2.25e-04 TGCCTCTGGC CAGGTGGT TACCTCTGTC chr17:45352820-45352900 20 2.25e-04 GCCTGGCCAG CAGGTGGT TACCTGAGTT chr22:19155952-19156032 17 2.25e-04 CCTGTCCGTC CAGGTAAA TGCCCCACTC chr10:75692212-75692292 42 2.25e-04 CTCAAACTCC CAGGTAAA GCCCAACCCG chr16:9167027-9167107 64 2.54e-04 CAACCACAAC CAGGTATT GCAGGACCT chr22:45127096-45127176 3 2.54e-04 GC CAGGTGTA CCTGTGTGGG chr2:70312485-70312565 20 2.54e-04 CCGCCCGTTA CAGGTGTA GCTCTTATCA chr17:56818530-56818610 3 2.54e-04 gc caggtatt aagtgactaa chr16:71460637-71460717 49 2.54e-04 ACCTGACAGC CAGGTGTA CAGGAGCAGG chr17:27564534-27564614 24 2.54e-04 GATACTCCTG CAGGTATT GCAGGTTCTA chr1:3773891-3773971 11 2.92e-04 CTGGGCACAC CAGGTGGC GTCGCGCCTT chr20:49347826-49347906 37 2.92e-04 GCCGCGGGCG CAGGTGCG CGCTTTCTAT chr6:136871667-136871747 58 2.92e-04 CCCTCGCGGG CAGGTGCG GCGTGGCAGC chr1:209979407-209979487 57 2.92e-04 CTGCCCAGCC CAGGTGCG CCGAGCTCAC chr11:118586753-11858683 13 2.92e-04 tggaaggcca caggtggc ctccttcacc chr4:54457816-54457896 15 3.09e-04 TACCTGCAAG CAGGTAGG TGGCGTCTCT chr2:68518540-68518620 42 3.41e-04 TCCCACGCTC CAGGTGCT CTGCCAGGGC chr1:184775634-184775714 29 3.41e-04 AGAAGTAGTT CAGGTATC TTATTCTCTG chr19:41172421-41172501 19 3.41e-04 ACCCGCCTGG CAGGTGCT GAGTCAGTGG chr6:27636482-27636562 21 3.41e-04 TGTCGAATCA CAGGTGCT CCGAATCGAA chr5:180600595-180600675 39 3.41e-04 TGTGATGGCA CAGGTATC CCATGCAGgt chr8:131012378-131012458 45 3.41e-04 CTTCCTTTCC CAGGTGCT GAGGAGAAGA chr4:38623027-38623107 42 3.41e-04 CTACTTTCCT CAGGTATC TGATCCAAGC chr6:126264341-126264421 6 3.41e-04 ttagc caggtgct gaagttctct chr15:90756903-90756983 37 3.74e-04 AGGGCCTGCC CAGGTGGA AACGCTCTTT chr6:13864177-13864257 16 3.74e-04 gttattagga caggtgga tagtggcctg chr2:171319278-171319358 26 3.74e-04 TCAGTCAGCC CAGGTAGT TGGGATAGAT chr6:158184610-158184690 11 3.74e-04 GTGTCCCTTC CAGGTGGA ACCCCTCCTC chr1:52088302-52088382 41 4.57e-04 cattcctcac caggtagc ctctccattg chr3:45133898-45133978 33 4.57e-04 tccttacctt caggagag ataaaaccca chr4:186240032-186240112 59 4.57e-04 aatatctcca caggtagc tactctgtgt chr5:75698261-75698341 42 4.57e-04 GGTGAGGGCA CAGGTACG GAAGCGTCCC chr8:96224824-96224904 44 5.04e-04 TTCCAGTGTG CAGGTGCA GGTTAAAGAT chr7:133886501-133886581 40 5.04e-04 GATGGACCTC CAGGTACT GCCCTTCAGG chr21:37525427-37525507 38 5.04e-04 cctgggagta caggtgca tgccatcaca chr6:138290124-138290204 39 5.19e-04 tgagcttgcc caggtaga gtagatagtg chr19:50637549-50637629 6 5.19e-04 cgagg caggtaga tcacgaggtc chr11:33342671-33342751 32 5.19e-04 aattcaagtg caggtaga ttaataatca chr1:160991101-160991181 58 5.53e-04 ACTGTCGCGT CAGGAGAC GAATTCCGCA chr3:43496824-43496904 63 5.85e-04 agaaggaaga caggtcag tggaggagag chr12:94494120-94494200 49 6.47e-04 GCACTCAGCC CAGGAGTG CGAACGGGGA chr3:46534570-46534650 3 6.47e-04 gc caggAAAt gatacctggt chr10:74021490-74021570 58 6.47e-04 tgcctgggat caggaaat gagcctagat chr1:39860434-39860514 61 6.47e-04 CTTGGAGAGA CAGGAAAT CACACTTGGT chr1:85187678-85187758 8 6.62e-04 gggcttc caggtcat aggtagataa chr11:123613252-12361333 23 6.62e-04 agggggcttc caggtcat aggtagataa chr21:45277521-45277601 46 6.77e-04 cacctgaggt caggagtt caagatcagt chr5:138088737-138088817 41 7.45e-04 CGGGCTGTTC CAGGAGTC ACCGCTCCTC chr2:20630833-20630913 54 8.23e-04 AAAAGGAACA CAGATGAG ATAGATGATT chr10:135203779-13520385 73 8.23e-04 gaggcctagg caggaggt chr5:159087579-159087659 4 8.23e-04 gtg cagatgag aggcccaggc chrX:153602046-153602126 52 8.23e-04 GCAGACTGGC AAGGTGAG AAGAGACCTG chr22:40451713-40451793 73 8.73e-04 TAGATCACCT GAGGTGAG chr1:207919904-207919984 66 8.73e-04 gggatctcaa gaggtgag gatcacc chr7:135667188-135667268 25 1.34e-03 tactttacat aaggtgaa cataaagaag -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CAGGTGAB MEME-1 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr4:40310331-40310411 1.7e-05 11_[+1]_61 chr10:50746791-50746871 1.7e-05 7_[+1]_65 chr9:135854199-135854279 1.7e-05 26_[+1]_46 chr7:73866808-73866888 1.7e-05 19_[+1]_53 chr11:118801020-11880110 1.7e-05 35_[+1]_37 chr10:3852423-3852503 1.7e-05 59_[+1]_13 chr6:135327832-135327912 1.7e-05 48_[+1]_24 chr16:9144511-9144591 1.7e-05 42_[+1]_30 chr14:100017783-10001786 1.7e-05 67_[+1]_5 chr19:39900163-39900243 1.7e-05 47_[+1]_25 chr19:45057128-45057208 1.7e-05 31_[+1]_41 chr1:27286869-27286949 1.7e-05 38_[+1]_34 chr16:90098699-90098779 1.7e-05 54_[+1]_18 chr10:74036359-74036439 1.7e-05 10_[+1]_62 chr19:14328365-14328445 1.7e-05 17_[+1]_55 chr22:38003240-38003320 1.7e-05 16_[+1]_56 chr22:21195375-21195455 3.3e-05 25_[+1]_47 chr1:202452648-202452728 3.3e-05 38_[+1]_34 chr8:144536449-144536529 3.3e-05 44_[+1]_28 chr16:11295808-11295888 5e-05 35_[+1]_37 chr3:195443017-195443097 5e-05 56_[+1]_16 chr1:31944529-31944609 5e-05 38_[+1]_34 chr5:140090597-140090677 5e-05 10_[+1]_62 chr6:166795483-166795563 5e-05 55_[+1]_17 chr16:11188054-11188134 5e-05 23_[+1]_49 chr16:1347051-1347131 5e-05 47_[+1]_25 chr2:236353027-236353107 5e-05 61_[+1]_11 chr15:91576458-91576538 5e-05 22_[+1]_50 chr2:80539532-80539612 5e-05 37_[+1]_35 chr2:8641059-8641139 5e-05 66_[+1]_6 chr3:14014613-14014693 5e-05 6_[+1]_66 chr6:87923291-87923371 5e-05 64_[+1]_8 chr17:38673229-38673309 6.5e-05 69_[+1]_3 chr6:109509244-109509324 6.5e-05 25_[+1]_47 chr19:54676824-54676904 6.5e-05 34_[+1]_38 chr12:48137965-48138045 6.5e-05 38_[+1]_34 chr6:161736529-161736609 0.00011 33_[+1]_39 chr14:69658230-69658310 0.00011 49_[+1]_23 chr18:8883068-8883148 0.00011 49_[+1]_23 chr8:129440620-129440700 0.00011 66_[+1]_6 chr12:118558523-11855860 0.00011 20_[+1]_52 chr10:63741416-63741496 0.00011 43_[+1]_29 chr3:101350400-101350480 0.00011 31_[+1]_41 chr14:31713297-31713377 0.00011 49_[+1]_23 chr11:73495430-73495510 0.00011 40_[+1]_32 chr20:48629239-48629319 0.00011 59_[+1]_13 chr8:145277514-145277594 0.00011 21_[+1]_51 chr11:10604355-10604435 0.00011 3_[+1]_69 chr1:15364802-15364882 0.00011 26_[+1]_46 chr8:80766287-80766367 0.00011 36_[+1]_36 chr2:11893772-11893852 0.00011 20_[+1]_52 chr5:82265207-82265287 0.00011 54_[+1]_18 chr9:138863950-138864030 0.00011 49_[+1]_23 chr1:22587458-22587538 0.00011 14_[+1]_58 chr2:27184793-27184873 0.00011 41_[+1]_31 chr6:41182711-41182791 0.00011 56_[+1]_16 chr1:67628827-67628907 0.00011 45_[+1]_27 chr3:197304683-197304763 0.00011 40_[+1]_32 chr5:149088704-149088784 0.00013 17_[+1]_55 chr1:201140085-201140165 0.00013 17_[+1]_55 chr7:120778429-120778509 0.00013 26_[+1]_46 chr20:382716-382796 0.00014 47_[+1]_25 chr15:63688019-63688099 0.00014 4_[+1]_68 chr12:123210726-12321080 0.00014 60_[+1]_12 chr10:29238062-29238142 0.00016 48_[+1]_24 chr20:62446930-62447010 0.00016 24_[+1]_48 chr1:154285576-154285656 0.00016 11_[+1]_61 chr1:27189399-27189479 0.00016 27_[+1]_45 chr12:123235892-12323597 0.00018 71_[+1]_1 chr6:10348175-10348255 0.00022 52_[+1]_20 chr19:909381-909461 0.00022 36_[+1]_36 chr20:44997134-44997214 0.00022 6_[+1]_66 chr2:15698279-15698359 0.00022 67_[+1]_5 chr6:28448064-28448144 0.00022 14_[+1]_58 chr21:45303933-45304013 0.00022 38_[+1]_34 chr17:45352820-45352900 0.00022 19_[+1]_53 chr22:19155952-19156032 0.00022 16_[+1]_56 chr10:75692212-75692292 0.00022 41_[+1]_31 chr16:9167027-9167107 0.00025 63_[+1]_9 chr22:45127096-45127176 0.00025 2_[+1]_70 chr2:70312485-70312565 0.00025 19_[+1]_53 chr17:56818530-56818610 0.00025 2_[+1]_70 chr16:71460637-71460717 0.00025 48_[+1]_24 chr17:27564534-27564614 0.00025 23_[+1]_49 chr1:3773891-3773971 0.00029 10_[+1]_62 chr20:49347826-49347906 0.00029 36_[+1]_36 chr6:136871667-136871747 0.00029 57_[+1]_15 chr1:209979407-209979487 0.00029 56_[+1]_16 chr11:118586753-11858683 0.00029 12_[+1]_60 chr4:54457816-54457896 0.00031 14_[+1]_58 chr2:68518540-68518620 0.00034 41_[+1]_31 chr1:184775634-184775714 0.00034 28_[+1]_44 chr19:41172421-41172501 0.00034 18_[+1]_54 chr6:27636482-27636562 0.00034 20_[+1]_52 chr5:180600595-180600675 0.00034 38_[+1]_34 chr8:131012378-131012458 0.00034 44_[+1]_28 chr4:38623027-38623107 0.00034 41_[+1]_31 chr6:126264341-126264421 0.00034 5_[+1]_67 chr15:90756903-90756983 0.00037 36_[+1]_36 chr6:13864177-13864257 0.00037 15_[+1]_57 chr2:171319278-171319358 0.00037 25_[+1]_47 chr6:158184610-158184690 0.00037 10_[+1]_62 chr1:52088302-52088382 0.00046 40_[+1]_32 chr3:45133898-45133978 0.00046 32_[+1]_40 chr4:186240032-186240112 0.00046 58_[+1]_14 chr5:75698261-75698341 0.00046 41_[+1]_31 chr8:96224824-96224904 0.0005 43_[+1]_29 chr7:133886501-133886581 0.0005 39_[+1]_33 chr21:37525427-37525507 0.0005 37_[+1]_35 chr6:138290124-138290204 0.00052 38_[+1]_34 chr19:50637549-50637629 0.00052 5_[+1]_67 chr11:33342671-33342751 0.00052 31_[+1]_41 chr1:160991101-160991181 0.00055 57_[+1]_15 chr3:43496824-43496904 0.00059 62_[+1]_10 chr12:94494120-94494200 0.00065 48_[+1]_24 chr3:46534570-46534650 0.00065 2_[+1]_70 chr10:74021490-74021570 0.00065 57_[+1]_15 chr1:39860434-39860514 0.00065 60_[+1]_12 chr1:85187678-85187758 0.00066 7_[+1]_65 chr11:123613252-12361333 0.00066 22_[+1]_50 chr21:45277521-45277601 0.00068 45_[+1]_27 chr5:138088737-138088817 0.00075 40_[+1]_32 chr2:20630833-20630913 0.00082 53_[+1]_19 chr10:135203779-13520385 0.00082 72_[+1] chr5:159087579-159087659 0.00082 3_[+1]_69 chrX:153602046-153602126 0.00082 51_[+1]_21 chr22:40451713-40451793 0.00087 72_[+1] chr1:207919904-207919984 0.00087 65_[+1]_7 chr7:135667188-135667268 0.0013 24_[+1]_48 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CAGGTGAB MEME-1 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF CAGGTGAB width=8 seqs=129 chr4:40310331-40310411 ( 12) CAGGTGAG 1 chr10:50746791-50746871 ( 8) CAGGTGAG 1 chr9:135854199-135854279 ( 27) CAGGTGAG 1 chr7:73866808-73866888 ( 20) CAGGTGAG 1 chr11:118801020-11880110 ( 36) CAGGTGAG 1 chr10:3852423-3852503 ( 60) CAGGTGAG 1 chr6:135327832-135327912 ( 49) CAGGTGAG 1 chr16:9144511-9144591 ( 43) CAGGTGAG 1 chr14:100017783-10001786 ( 68) CAGGTGAG 1 chr19:39900163-39900243 ( 48) CAGGTGAG 1 chr19:45057128-45057208 ( 32) CAGGTGAG 1 chr1:27286869-27286949 ( 39) CAGGTGAG 1 chr16:90098699-90098779 ( 55) CAGGTGAG 1 chr10:74036359-74036439 ( 11) CAGGTGAG 1 chr19:14328365-14328445 ( 18) CAGGTGAG 1 chr22:38003240-38003320 ( 17) CAGGTGAG 1 chr22:21195375-21195455 ( 26) CAGGTGAT 1 chr1:202452648-202452728 ( 39) CAGGTGAT 1 chr8:144536449-144536529 ( 45) CAGGTGAT 1 chr16:11295808-11295888 ( 36) CAGGTGAC 1 chr3:195443017-195443097 ( 57) CAGGTGAC 1 chr1:31944529-31944609 ( 39) CAGGTGAC 1 chr5:140090597-140090677 ( 11) CAGGTGAC 1 chr6:166795483-166795563 ( 56) CAGGTGAC 1 chr16:11188054-11188134 ( 24) CAGGTGAC 1 chr16:1347051-1347131 ( 48) CAGGTGAC 1 chr2:236353027-236353107 ( 62) CAGGTGAC 1 chr15:91576458-91576538 ( 23) CAGGTGAC 1 chr2:80539532-80539612 ( 38) CAGGTGAC 1 chr2:8641059-8641139 ( 67) CAGGTGAC 1 chr3:14014613-14014693 ( 7) CAGGTGAC 1 chr6:87923291-87923371 ( 65) CAGGTGAC 1 chr17:38673229-38673309 ( 70) CAGGTAAG 1 chr6:109509244-109509324 ( 26) CAGGTAAG 1 chr19:54676824-54676904 ( 35) CAGGTAAG 1 chr12:48137965-48138045 ( 39) CAGGTAAG 1 chr6:161736529-161736609 ( 34) CAGGTAAT 1 chr14:69658230-69658310 ( 50) CAGGTGTG 1 chr18:8883068-8883148 ( 50) CAGGTAAT 1 chr8:129440620-129440700 ( 67) CAGGTAAT 1 chr12:118558523-11855860 ( 21) CAGGTGTG 1 chr10:63741416-63741496 ( 44) CAGGTGTG 1 chr3:101350400-101350480 ( 32) CAGGTAAT 1 chr14:31713297-31713377 ( 50) CAGGTAAT 1 chr11:73495430-73495510 ( 41) CAGGTGTG 1 chr20:48629239-48629319 ( 60) CAGGTGAA 1 chr8:145277514-145277594 ( 22) CAGGTGTG 1 chr11:10604355-10604435 ( 4) CAGGTGTG 1 chr1:15364802-15364882 ( 27) CAGGTAAT 1 chr8:80766287-80766367 ( 37) CAGGTGTG 1 chr2:11893772-11893852 ( 21) CAGGTAAT 1 chr5:82265207-82265287 ( 55) CAGGTAAT 1 chr9:138863950-138864030 ( 50) CAGGTGTG 1 chr1:22587458-22587538 ( 15) CAGGTGTG 1 chr2:27184793-27184873 ( 42) CAGGTGTG 1 chr6:41182711-41182791 ( 57) CAGGTGAA 1 chr1:67628827-67628907 ( 46) CAGGTGTG 1 chr3:197304683-197304763 ( 41) CAGGTAAT 1 chr5:149088704-149088784 ( 18) CAGGTGTT 1 chr1:201140085-201140165 ( 18) CAGGTGTT 1 chr7:120778429-120778509 ( 27) CAGGTGTT 1 chr20:382716-382796 ( 48) CAGGTAAC 1 chr15:63688019-63688099 ( 5) CAGGTAAC 1 chr12:123210726-12321080 ( 61) CAGGTAAC 1 chr10:29238062-29238142 ( 49) CAGGTGGG 1 chr20:62446930-62447010 ( 25) CAGGTGGG 1 chr1:154285576-154285656 ( 12) CAGGTGGG 1 chr1:27189399-27189479 ( 28) CAGGTGGG 1 chr12:123235892-12323597 ( 72) CAGGTGTC 1 chr6:10348175-10348255 ( 53) CAGGTGGT 1 chr19:909381-909461 ( 37) CAGGTAAA 1 chr20:44997134-44997214 ( 7) CAGGTAAA 1 chr2:15698279-15698359 ( 68) CAGGTGGT 1 chr6:28448064-28448144 ( 15) CAGGTAAA 1 chr21:45303933-45304013 ( 39) CAGGTGGT 1 chr17:45352820-45352900 ( 20) CAGGTGGT 1 chr22:19155952-19156032 ( 17) CAGGTAAA 1 chr10:75692212-75692292 ( 42) CAGGTAAA 1 chr16:9167027-9167107 ( 64) CAGGTATT 1 chr22:45127096-45127176 ( 3) CAGGTGTA 1 chr2:70312485-70312565 ( 20) CAGGTGTA 1 chr17:56818530-56818610 ( 3) CAGGTATT 1 chr16:71460637-71460717 ( 49) CAGGTGTA 1 chr17:27564534-27564614 ( 24) CAGGTATT 1 chr1:3773891-3773971 ( 11) CAGGTGGC 1 chr20:49347826-49347906 ( 37) CAGGTGCG 1 chr6:136871667-136871747 ( 58) CAGGTGCG 1 chr1:209979407-209979487 ( 57) CAGGTGCG 1 chr11:118586753-11858683 ( 13) CAGGTGGC 1 chr4:54457816-54457896 ( 15) CAGGTAGG 1 chr2:68518540-68518620 ( 42) CAGGTGCT 1 chr1:184775634-184775714 ( 29) CAGGTATC 1 chr19:41172421-41172501 ( 19) CAGGTGCT 1 chr6:27636482-27636562 ( 21) CAGGTGCT 1 chr5:180600595-180600675 ( 39) CAGGTATC 1 chr8:131012378-131012458 ( 45) CAGGTGCT 1 chr4:38623027-38623107 ( 42) CAGGTATC 1 chr6:126264341-126264421 ( 6) CAGGTGCT 1 chr15:90756903-90756983 ( 37) CAGGTGGA 1 chr6:13864177-13864257 ( 16) CAGGTGGA 1 chr2:171319278-171319358 ( 26) CAGGTAGT 1 chr6:158184610-158184690 ( 11) CAGGTGGA 1 chr1:52088302-52088382 ( 41) CAGGTAGC 1 chr3:45133898-45133978 ( 33) CAGGAGAG 1 chr4:186240032-186240112 ( 59) CAGGTAGC 1 chr5:75698261-75698341 ( 42) CAGGTACG 1 chr8:96224824-96224904 ( 44) CAGGTGCA 1 chr7:133886501-133886581 ( 40) CAGGTACT 1 chr21:37525427-37525507 ( 38) CAGGTGCA 1 chr6:138290124-138290204 ( 39) CAGGTAGA 1 chr19:50637549-50637629 ( 6) CAGGTAGA 1 chr11:33342671-33342751 ( 32) CAGGTAGA 1 chr1:160991101-160991181 ( 58) CAGGAGAC 1 chr3:43496824-43496904 ( 63) CAGGTCAG 1 chr12:94494120-94494200 ( 49) CAGGAGTG 1 chr3:46534570-46534650 ( 3) CAGGAAAT 1 chr10:74021490-74021570 ( 58) CAGGAAAT 1 chr1:39860434-39860514 ( 61) CAGGAAAT 1 chr1:85187678-85187758 ( 8) CAGGTCAT 1 chr11:123613252-12361333 ( 23) CAGGTCAT 1 chr21:45277521-45277601 ( 46) CAGGAGTT 1 chr5:138088737-138088817 ( 41) CAGGAGTC 1 chr2:20630833-20630913 ( 54) CAGATGAG 1 chr10:135203779-13520385 ( 73) CAGGAGGT 1 chr5:159087579-159087659 ( 4) CAGATGAG 1 chrX:153602046-153602126 ( 52) AAGGTGAG 1 chr22:40451713-40451793 ( 73) GAGGTGAG 1 chr1:207919904-207919984 ( 66) GAGGTGAG 1 chr7:135667188-135667268 ( 25) AAGGTGAA 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CAGGTGAB MEME-1 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 7.88272 E= 8.2e-074 -394 191 -410 -1366 207 -1366 -1366 -1366 -1366 -1366 191 -1366 -394 -1366 189 -1366 -177 -1366 -1366 197 34 -347 134 -1366 117 -147 -71 -18 -70 -36 48 23 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CAGGTGAB MEME-1 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 129 E= 8.2e-074 0.015504 0.968992 0.015504 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.015504 0.000000 0.984496 0.000000 0.069767 0.000000 0.000000 0.930233 0.302326 0.023256 0.674419 0.000000 0.534884 0.093023 0.162791 0.209302 0.147287 0.201550 0.372093 0.279070 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CAGGTGAB MEME-1 regular expression -------------------------------------------------------------------------------- CAGGT[GA][AT][GTC] -------------------------------------------------------------------------------- Time 5.02 secs. ******************************************************************************** ******************************************************************************** MOTIF CWCACCTG MEME-2 width = 8 sites = 66 llr = 558 E-value = 2.4e-039 ******************************************************************************** -------------------------------------------------------------------------------- Motif CWCACCTG MEME-2 Description -------------------------------------------------------------------------------- Simplified A 13:a:::: pos.-specific C 6:8:aa:: probability G 21:::::a matrix T 162:::a: bits 2.1 * * 1.9 **** 1.7 ***** 1.5 ***** Relative 1.2 ****** Entropy 1.0 ****** (12.2 bits) 0.8 ******* 0.6 ******* 0.4 ******** 0.2 ******** 0.0 -------- Multilevel CTCACCTG consensus GA sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CWCACCTG MEME-2 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr6:43905205-43905285 70 1.58e-05 CCTGTGGTCA CTCACCTG ACA chr6:34294991-34295071 52 1.58e-05 ggcgcggtgg ctcacctg taatcccagc chr22:45127096-45127176 51 1.58e-05 TGATGCAGGT CTCACCTG TGCCGAGTGT chr2:18739904-18739984 24 1.58e-05 catccttctg ctcacctg agataaatgc chr11:71159292-71159372 39 1.58e-05 ACCTTGGCCA CTCACCTG CGCACACCTC chr8:1326582-1326662 19 1.58e-05 CACACCTGAC CTCACCTG TCCATCCTGC chr16:89209032-89209112 60 1.58e-05 cagagacacc ctcacctg cagagataca chr1:27286869-27286949 26 1.58e-05 CCCCTCGCCG CTCACCTG GGGCGCAGGT chr10:61895010-61895090 68 1.58e-05 acctccccat ctcacctg ggagg chr19:11320690-11320770 33 1.58e-05 tgtccaccct ctcacctg tccatccctt chr1:233760158-233760238 53 1.58e-05 ttcacctggc ctcacctg tcttcacctg chr19:9969614-9969694 26 1.58e-05 AAGGTAGACC CTCACCTG GCTAAGGTAG chr22:19155952-19156032 36 1.58e-05 GCCCCACTCA CTCACCTG TGCACCTTGG chr2:7006508-7006588 44 1.58e-05 TTTGCACACA CTCACCTG TGCACAAGCT chr20:51040993-51041073 34 1.58e-05 cctacctgca ctcacctg cacctacctg chr20:48675986-48676066 65 3.16e-05 cgtggtgttg cacacctg taattcca chr4:40310331-40310411 49 3.16e-05 ATCTTTCTAT CACACCTG TCACCGTGGT chr16:11295808-11295888 56 3.16e-05 ACACATGGCG CACACCTG TGACGCCCCC chr10:135203779-13520385 38 3.16e-05 ggcagtggct cacacctg taatcctagt chr5:140090597-140090677 47 3.16e-05 AAACCGGGGA CACACCTG CGGAAGAGCT chr15:65545164-65545244 38 3.16e-05 cgtggtggct cacacctg taatcccagc chr11:10604355-10604435 18 3.16e-05 tgtggtggca cacacctg taatcccagg chr6:166795483-166795563 40 3.16e-05 CCGCCTCTGG CACACCTG GACGGCCGCA chr12:133006557-13300663 47 3.16e-05 cacacctgag cacacctg cacacactgg chr1:1059342-1059422 41 3.16e-05 cacctgagca cacacctg tgcacactcc chr21:37525427-37525507 52 3.16e-05 tgcatgccat cacacctg gctaatacaa chr5:43197805-43197885 21 3.16e-05 CTTGCTGAAT CACACCTG GAAATTCCTT chr2:8641059-8641139 14 3.16e-05 GCAGGTAGTA CACACCTG AGTGCCAGGT chr1:1059142-1059222 49 3.16e-05 cacctgagca cacacctg cgcacacacc chr6:28047834-28047914 34 4.78e-05 gtcaccttta gtcacctg ttccgtaacc chr16:12707633-12707713 26 4.78e-05 tgttccactg gtcacctg ctttgacctg chr1:26595539-26595619 12 4.78e-05 agtcaccctg gtcacctg ctctgaccta chr5:149489646-149489726 19 4.78e-05 tttgacctga gtcacctg ctccatcctg chr6:29813284-29813364 32 4.78e-05 actcattcca gtcacctg ctccaccctg chr4:2956828-2956908 34 4.78e-05 GCCCCCTCTA GTCACCTG CACCCCACGG chr2:48512244-48512324 13 4.78e-05 actcatccca gtcacctg ctttgacctg chr10:63741416-63741496 34 7.86e-05 TGGACCTTAT CTTACCTG TTCAGGTGTG chr1:27995619-27995699 60 7.86e-05 tacccgcatc cttacctg cacccttact chr16:2193559-2193639 41 7.86e-05 GGCAGGGATG GACACCTG TTTGTCCCGA chr1:209979407-209979487 42 7.86e-05 CGCACCAGCC CTTACCTG CCCAGCCCAG chr11:108211860-10821194 33 7.86e-05 ctccacctga cttacctg gtcttttgca chr10:75692212-75692292 16 7.86e-05 TCTCCCTCCC GACACCTG CATGGTGACT chr21:45277521-45277601 34 9.31e-05 aggtgggcag atcacctg aggtcaggag chr3:47523325-47523405 58 9.31e-05 ttaggatact atcacctg agcgaatttc chr16:71460637-71460717 36 9.31e-05 AGGATGTGCC ATCACCTG ACAGCCAGGT chr10:3797421-3797501 3 9.31e-05 TC ATCACCTG TCTGAAAGGG chr17:16302084-16302164 51 1.08e-04 CTGCTCTGGG CATACCTG CAGTCAAATC chr16:87495162-87495242 8 1.08e-04 TTCATCT CATACCTG GACGGTAGGT chr16:4304190-4304270 6 1.40e-04 CGTTT CGCACCTG GCCGAAAGGG chr3:101350400-101350480 18 1.40e-04 AATACAAGGT AACACCTG TAATACCAGg chr7:127228953-127229033 60 1.40e-04 GATAACGACG CGCACCTG GAGGCGCTCC chr19:39900163-39900243 28 1.54e-04 GGCCTGGCCG TTCACCTG AAAGGGTGGG chr12:48137965-48138045 27 1.54e-04 GCTTGCCACA TTCACCTG AGCTCAGGTA chr16:12706615-12706695 45 1.69e-04 gtcaacgctg gttacctg ctctgacttc chr6:119580378-119580458 23 1.69e-04 TTTGTAAACA GTTACCTG CACAAGGATC chr6:158184610-158184690 51 1.84e-04 CCCGGCTCCA TACACCTG CCTGATTCCA chr3:46534570-46534650 11 1.99e-04 gccaggAAAt gatacctg gtgtaatgcc chr3:156827459-156827539 55 2.46e-04 GGGTTCTGAC CTCACCTC TGGCGTCAGT chr19:48151704-48151784 54 2.46e-04 gatagcgatc ggcacctg cagtaaagca chr6:3348241-3348321 49 2.46e-04 tctccttcat ggcacctg tcccagctgt chr1:165812122-165812202 40 2.46e-04 CTCTTGAGAG CTCACCTC CACACTAGTG chr11:118482002-11848208 29 2.91e-04 atcttctccc cacacctc tctccttatc chr4:54457816-54457896 3 2.91e-04 TG AATACCTG CAAGCAGGTA chr1:59351054-59351134 54 3.07e-04 AACTCTAGAA AGCACCTG TGTTGTTTTA chr8:131012378-131012458 15 3.07e-04 CTTCAGCCAC AGCACCTG ACTTACTTAT chr10:79728991-79729071 58 3.20e-04 GAGATTGTGA TTTACCTG TAACACCAGT -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CWCACCTG MEME-2 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr6:43905205-43905285 1.6e-05 69_[+2]_3 chr6:34294991-34295071 1.6e-05 51_[+2]_21 chr22:45127096-45127176 1.6e-05 50_[+2]_22 chr2:18739904-18739984 1.6e-05 23_[+2]_49 chr11:71159292-71159372 1.6e-05 38_[+2]_34 chr8:1326582-1326662 1.6e-05 18_[+2]_54 chr16:89209032-89209112 1.6e-05 59_[+2]_13 chr1:27286869-27286949 1.6e-05 25_[+2]_47 chr10:61895010-61895090 1.6e-05 67_[+2]_5 chr19:11320690-11320770 1.6e-05 32_[+2]_40 chr1:233760158-233760238 1.6e-05 52_[+2]_20 chr19:9969614-9969694 1.6e-05 25_[+2]_47 chr22:19155952-19156032 1.6e-05 35_[+2]_37 chr2:7006508-7006588 1.6e-05 43_[+2]_29 chr20:51040993-51041073 1.6e-05 33_[+2]_39 chr20:48675986-48676066 3.2e-05 64_[+2]_8 chr4:40310331-40310411 3.2e-05 48_[+2]_24 chr16:11295808-11295888 3.2e-05 55_[+2]_17 chr10:135203779-13520385 3.2e-05 37_[+2]_35 chr5:140090597-140090677 3.2e-05 46_[+2]_26 chr15:65545164-65545244 3.2e-05 37_[+2]_35 chr11:10604355-10604435 3.2e-05 17_[+2]_55 chr6:166795483-166795563 3.2e-05 39_[+2]_33 chr12:133006557-13300663 3.2e-05 46_[+2]_26 chr1:1059342-1059422 3.2e-05 40_[+2]_32 chr21:37525427-37525507 3.2e-05 51_[+2]_21 chr5:43197805-43197885 3.2e-05 20_[+2]_52 chr2:8641059-8641139 3.2e-05 13_[+2]_59 chr1:1059142-1059222 3.2e-05 48_[+2]_24 chr6:28047834-28047914 4.8e-05 33_[+2]_39 chr16:12707633-12707713 4.8e-05 25_[+2]_47 chr1:26595539-26595619 4.8e-05 11_[+2]_61 chr5:149489646-149489726 4.8e-05 18_[+2]_54 chr6:29813284-29813364 4.8e-05 31_[+2]_41 chr4:2956828-2956908 4.8e-05 33_[+2]_39 chr2:48512244-48512324 4.8e-05 12_[+2]_60 chr10:63741416-63741496 7.9e-05 33_[+2]_39 chr1:27995619-27995699 7.9e-05 59_[+2]_13 chr16:2193559-2193639 7.9e-05 40_[+2]_32 chr1:209979407-209979487 7.9e-05 41_[+2]_31 chr11:108211860-10821194 7.9e-05 32_[+2]_40 chr10:75692212-75692292 7.9e-05 15_[+2]_57 chr21:45277521-45277601 9.3e-05 33_[+2]_39 chr3:47523325-47523405 9.3e-05 57_[+2]_15 chr16:71460637-71460717 9.3e-05 35_[+2]_37 chr10:3797421-3797501 9.3e-05 2_[+2]_70 chr17:16302084-16302164 0.00011 50_[+2]_22 chr16:87495162-87495242 0.00011 7_[+2]_65 chr16:4304190-4304270 0.00014 5_[+2]_67 chr3:101350400-101350480 0.00014 17_[+2]_55 chr7:127228953-127229033 0.00014 59_[+2]_13 chr19:39900163-39900243 0.00015 27_[+2]_45 chr12:48137965-48138045 0.00015 26_[+2]_46 chr16:12706615-12706695 0.00017 44_[+2]_28 chr6:119580378-119580458 0.00017 22_[+2]_50 chr6:158184610-158184690 0.00018 50_[+2]_22 chr3:46534570-46534650 0.0002 10_[+2]_62 chr3:156827459-156827539 0.00025 54_[+2]_18 chr19:48151704-48151784 0.00025 53_[+2]_19 chr6:3348241-3348321 0.00025 48_[+2]_24 chr1:165812122-165812202 0.00025 39_[+2]_33 chr11:118482002-11848208 0.00029 28_[+2]_44 chr4:54457816-54457896 0.00029 2_[+2]_70 chr1:59351054-59351134 0.00031 53_[+2]_19 chr8:131012378-131012458 0.00031 14_[+2]_58 chr10:79728991-79729071 0.00032 57_[+2]_15 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CWCACCTG MEME-2 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF CWCACCTG width=8 seqs=66 chr6:43905205-43905285 ( 70) CTCACCTG 1 chr6:34294991-34295071 ( 52) CTCACCTG 1 chr22:45127096-45127176 ( 51) CTCACCTG 1 chr2:18739904-18739984 ( 24) CTCACCTG 1 chr11:71159292-71159372 ( 39) CTCACCTG 1 chr8:1326582-1326662 ( 19) CTCACCTG 1 chr16:89209032-89209112 ( 60) CTCACCTG 1 chr1:27286869-27286949 ( 26) CTCACCTG 1 chr10:61895010-61895090 ( 68) CTCACCTG 1 chr19:11320690-11320770 ( 33) CTCACCTG 1 chr1:233760158-233760238 ( 53) CTCACCTG 1 chr19:9969614-9969694 ( 26) CTCACCTG 1 chr22:19155952-19156032 ( 36) CTCACCTG 1 chr2:7006508-7006588 ( 44) CTCACCTG 1 chr20:51040993-51041073 ( 34) CTCACCTG 1 chr20:48675986-48676066 ( 65) CACACCTG 1 chr4:40310331-40310411 ( 49) CACACCTG 1 chr16:11295808-11295888 ( 56) CACACCTG 1 chr10:135203779-13520385 ( 38) CACACCTG 1 chr5:140090597-140090677 ( 47) CACACCTG 1 chr15:65545164-65545244 ( 38) CACACCTG 1 chr11:10604355-10604435 ( 18) CACACCTG 1 chr6:166795483-166795563 ( 40) CACACCTG 1 chr12:133006557-13300663 ( 47) CACACCTG 1 chr1:1059342-1059422 ( 41) CACACCTG 1 chr21:37525427-37525507 ( 52) CACACCTG 1 chr5:43197805-43197885 ( 21) CACACCTG 1 chr2:8641059-8641139 ( 14) CACACCTG 1 chr1:1059142-1059222 ( 49) CACACCTG 1 chr6:28047834-28047914 ( 34) GTCACCTG 1 chr16:12707633-12707713 ( 26) GTCACCTG 1 chr1:26595539-26595619 ( 12) GTCACCTG 1 chr5:149489646-149489726 ( 19) GTCACCTG 1 chr6:29813284-29813364 ( 32) GTCACCTG 1 chr4:2956828-2956908 ( 34) GTCACCTG 1 chr2:48512244-48512324 ( 13) GTCACCTG 1 chr10:63741416-63741496 ( 34) CTTACCTG 1 chr1:27995619-27995699 ( 60) CTTACCTG 1 chr16:2193559-2193639 ( 41) GACACCTG 1 chr1:209979407-209979487 ( 42) CTTACCTG 1 chr11:108211860-10821194 ( 33) CTTACCTG 1 chr10:75692212-75692292 ( 16) GACACCTG 1 chr21:45277521-45277601 ( 34) ATCACCTG 1 chr3:47523325-47523405 ( 58) ATCACCTG 1 chr16:71460637-71460717 ( 36) ATCACCTG 1 chr10:3797421-3797501 ( 3) ATCACCTG 1 chr17:16302084-16302164 ( 51) CATACCTG 1 chr16:87495162-87495242 ( 8) CATACCTG 1 chr16:4304190-4304270 ( 6) CGCACCTG 1 chr3:101350400-101350480 ( 18) AACACCTG 1 chr7:127228953-127229033 ( 60) CGCACCTG 1 chr19:39900163-39900243 ( 28) TTCACCTG 1 chr12:48137965-48138045 ( 27) TTCACCTG 1 chr16:12706615-12706695 ( 45) GTTACCTG 1 chr6:119580378-119580458 ( 23) GTTACCTG 1 chr6:158184610-158184690 ( 51) TACACCTG 1 chr3:46534570-46534650 ( 11) GATACCTG 1 chr3:156827459-156827539 ( 55) CTCACCTC 1 chr19:48151704-48151784 ( 54) GGCACCTG 1 chr6:3348241-3348321 ( 49) GGCACCTG 1 chr1:165812122-165812202 ( 40) CTCACCTC 1 chr11:118482002-11848208 ( 29) CACACCTC 1 chr4:54457816-54457896 ( 3) AATACCTG 1 chr1:59351054-59351134 ( 54) AGCACCTG 1 chr8:131012378-131012458 ( 15) AGCACCTG 1 chr10:79728991-79729071 ( 58) TTTACCTG 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CWCACCTG MEME-2 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 10.2669 E= 2.4e-039 -98 123 -33 -197 55 -1269 -155 124 -1269 169 -1269 -51 207 -1269 -1269 -1269 -1269 196 -1269 -1269 -1269 196 -1269 -1269 -1269 -1269 -1269 207 -1269 -250 184 -1269 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CWCACCTG MEME-2 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 66 E= 2.4e-039 0.121212 0.606061 0.212121 0.060606 0.348485 0.000000 0.090909 0.560606 0.000000 0.833333 0.000000 0.166667 1.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.045455 0.954545 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CWCACCTG MEME-2 regular expression -------------------------------------------------------------------------------- [CG][TA]CACCTG -------------------------------------------------------------------------------- Time 8.65 secs. ******************************************************************************** ******************************************************************************** MOTIF MTGASTCA MEME-3 width = 8 sites = 51 llr = 455 E-value = 1.1e-031 ******************************************************************************** -------------------------------------------------------------------------------- Motif MTGASTCA MEME-3 Description -------------------------------------------------------------------------------- Simplified A 5::a1::a pos.-specific C 3:::5:a: probability G 2:a:4::: matrix T :a::1a:: bits 2.1 * * * * 1.9 *** * * 1.7 *** *** 1.5 *** *** Relative 1.2 *** *** Entropy 1.0 *** *** (12.9 bits) 0.8 *** *** 0.6 **** *** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel ATGACTCA consensus C G sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif MTGASTCA MEME-3 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr19:41172421-41172501 53 1.34e-05 TTACCACGCT ATGACTCA GAGGTTATCA chr3:195443017-195443097 41 1.34e-05 ttgactcagg atgactca gattagagca chr17:16302084-16302164 28 1.34e-05 CACATCTGCA ATGACTCA GATCTCTGCT chr1:202452648-202452728 23 1.34e-05 gtgactcagg atgactca ggtcagagca chr10:75692212-75692292 67 1.34e-05 CCGATGGGAA ATGACTCA GCATTG chr6:161736529-161736609 18 2.72e-05 ggtaatcaga aTGAGTca gggtgaagca chr6:28889981-28890061 45 2.72e-05 ATCTTAAACA ATGAGTCA TCTACCTGTC chr7:73866808-73866888 4 2.72e-05 gtc atgagtca cacaggtcca chr5:159087579-159087659 37 2.72e-05 ataaaaatgt atgagtca taggcataga chr14:31713297-31713377 62 2.72e-05 ggtaatcgga atgagtca gggtggaggt chr21:45303933-45304013 64 2.72e-05 GTCACCAGAG ATGAGTCA CCCAGTCTC chr3:43496824-43496904 12 2.72e-05 gaggcaggcc aTGAgtca gaggtatgac chr5:82265207-82265287 22 2.72e-05 tggttatgga atgagtca gagtggagga chr6:158184610-158184690 33 2.72e-05 CTCCTCCTCC ATGAGTCA CCCGGCTCCA chr6:41182711-41182791 69 2.72e-05 ggtgaacagg atgagtca ggat chr11:108211860-10821194 14 2.72e-05 gcttgtatag atgagtca tctccacctg chr2:80539532-80539612 50 2.72e-05 ggtgaccaga atgagtca ggacagagca chr1:67628827-67628907 23 2.72e-05 CATCATTTGG ATGAGTCA AAAGATGTAT chr16:12707633-12707713 69 4.18e-05 ctgctgtgtc ctgactca tcct chr5:149489646-149489726 34 4.18e-05 ctgctccatc ctgactca tcctgagcca chr6:29813284-29813364 19 4.18e-05 ctgctccacc ctgactca ttccagtcac chr2:103281019-103281099 49 4.18e-05 GGGAGGATGA CTGACTCA TCTTGGGTAC chr22:47169896-47169976 19 4.18e-05 ACAGAGAAAG CTGACTCA CTCACCAGGA chr6:119580378-119580458 4 4.18e-05 TTG CTGACTCA TTTTGTAAAC chr3:197304683-197304763 69 4.18e-05 GGGCGTCTCT CTGACTCA CGGC chr10:3797421-3797501 33 4.18e-05 CCTGTTGTAA CTGACTCA GCTGAGATTC chr15:51892467-51892547 39 4.18e-05 tagaatctac ctgactca ccctaatgac chr16:12706615-12706695 31 5.67e-05 ctactccatc ctgagtca acgctggtta chr18:33039027-33039107 52 5.67e-05 TTCCTCCTGC CTGAGTCA CTGTTCCAGG chr6:28047834-28047914 20 5.67e-05 ctgctctgac ctgagtca cctttagtca chr8:128872135-128872215 7 5.67e-05 GAGAGG CTGAGTCA TACAGATCCT chr8:80766287-80766367 23 5.67e-05 CAGAGAGGAG CTGAGTCA CAACAACAGG chr2:48512244-48512324 28 5.67e-05 ctgctttgac ctgagtca cccctggtca chr14:31500902-31500982 60 5.67e-05 TAAACTGTGG CTGAGTCA TTTCCTCTCT chr1:31944529-31944609 23 7.17e-05 ggtgacaggg gtgactca agatggagca chr1:154285576-154285656 71 7.17e-05 AAATCCTTCT GTGACTCA TG chr22:40451713-40451793 10 7.17e-05 TAGAAAGTG GTGACTCA TTTAAGCTTA chr15:63688019-63688099 47 7.17e-05 gtgaccaagg gtgactca ggtcaaagaa chr16:1347051-1347131 22 7.17e-05 tatagaacag gtgactca ggatgtgtca chr2:236353027-236353107 47 7.17e-05 gtgaccagtg gtgactca gtcaaagcag chr3:14014613-14014693 20 7.17e-05 gtgactaaag gtgactca ggtcagagca chr6:87923291-87923371 50 7.17e-05 gtgaccaggg gtgactca ggtaaagcag chr1:39860434-39860514 2 8.72e-05 A GTGAGTCA CTGGAGGATA chr2:20630833-20630913 66 1.12e-04 GATGAGATAG ATGATTCA CAGCAGA chr6:10348175-10348255 10 1.12e-04 AGGGAGGGG ATGAATCA GGATGACACT chr16:9167027-9167107 19 1.12e-04 TAGATCTGCC ATGAATCA GCCAGAGGGG chrX:135213383-135213463 1 1.12e-04 . atgaatca tccctttgtc chr17:56818530-56818610 46 1.12e-04 atacagaggg atgattca tgttccaggc chr1:27189399-27189479 70 1.12e-04 GACTGTTCTG ATGATTCA CCC chr12:123210726-12321080 21 1.79e-04 AGGAGGATGT ATGACTAA TGCTGGTAAG chr1:201140085-201140165 28 2.19e-04 CAGGTGTTAC CTGAGTAA GATTGAGATT -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif MTGASTCA MEME-3 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr19:41172421-41172501 1.3e-05 52_[+3]_20 chr3:195443017-195443097 1.3e-05 40_[+3]_32 chr17:16302084-16302164 1.3e-05 27_[+3]_45 chr1:202452648-202452728 1.3e-05 22_[+3]_50 chr10:75692212-75692292 1.3e-05 66_[+3]_6 chr6:161736529-161736609 2.7e-05 17_[+3]_55 chr6:28889981-28890061 2.7e-05 44_[+3]_28 chr7:73866808-73866888 2.7e-05 3_[+3]_69 chr5:159087579-159087659 2.7e-05 36_[+3]_36 chr14:31713297-31713377 2.7e-05 61_[+3]_11 chr21:45303933-45304013 2.7e-05 63_[+3]_9 chr3:43496824-43496904 2.7e-05 11_[+3]_61 chr5:82265207-82265287 2.7e-05 21_[+3]_51 chr6:158184610-158184690 2.7e-05 32_[+3]_40 chr6:41182711-41182791 2.7e-05 68_[+3]_4 chr11:108211860-10821194 2.7e-05 13_[+3]_59 chr2:80539532-80539612 2.7e-05 49_[+3]_23 chr1:67628827-67628907 2.7e-05 22_[+3]_50 chr16:12707633-12707713 4.2e-05 68_[+3]_4 chr5:149489646-149489726 4.2e-05 33_[+3]_39 chr6:29813284-29813364 4.2e-05 18_[+3]_54 chr2:103281019-103281099 4.2e-05 48_[+3]_24 chr22:47169896-47169976 4.2e-05 18_[+3]_54 chr6:119580378-119580458 4.2e-05 3_[+3]_69 chr3:197304683-197304763 4.2e-05 68_[+3]_4 chr10:3797421-3797501 4.2e-05 32_[+3]_40 chr15:51892467-51892547 4.2e-05 38_[+3]_34 chr16:12706615-12706695 5.7e-05 30_[+3]_42 chr18:33039027-33039107 5.7e-05 51_[+3]_21 chr6:28047834-28047914 5.7e-05 19_[+3]_53 chr8:128872135-128872215 5.7e-05 6_[+3]_66 chr8:80766287-80766367 5.7e-05 22_[+3]_50 chr2:48512244-48512324 5.7e-05 27_[+3]_45 chr14:31500902-31500982 5.7e-05 59_[+3]_13 chr1:31944529-31944609 7.2e-05 22_[+3]_50 chr1:154285576-154285656 7.2e-05 70_[+3]_2 chr22:40451713-40451793 7.2e-05 9_[+3]_63 chr15:63688019-63688099 7.2e-05 46_[+3]_26 chr16:1347051-1347131 7.2e-05 21_[+3]_51 chr2:236353027-236353107 7.2e-05 46_[+3]_26 chr3:14014613-14014693 7.2e-05 19_[+3]_53 chr6:87923291-87923371 7.2e-05 49_[+3]_23 chr1:39860434-39860514 8.7e-05 1_[+3]_71 chr2:20630833-20630913 0.00011 65_[+3]_7 chr6:10348175-10348255 0.00011 9_[+3]_63 chr16:9167027-9167107 0.00011 18_[+3]_54 chrX:135213383-135213463 0.00011 [+3]_72 chr17:56818530-56818610 0.00011 45_[+3]_27 chr1:27189399-27189479 0.00011 69_[+3]_3 chr12:123210726-12321080 0.00018 20_[+3]_52 chr1:201140085-201140165 0.00022 27_[+3]_45 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif MTGASTCA MEME-3 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF MTGASTCA width=8 seqs=51 chr19:41172421-41172501 ( 53) ATGACTCA 1 chr3:195443017-195443097 ( 41) ATGACTCA 1 chr17:16302084-16302164 ( 28) ATGACTCA 1 chr1:202452648-202452728 ( 23) ATGACTCA 1 chr10:75692212-75692292 ( 67) ATGACTCA 1 chr6:161736529-161736609 ( 18) ATGAGTCA 1 chr6:28889981-28890061 ( 45) ATGAGTCA 1 chr7:73866808-73866888 ( 4) ATGAGTCA 1 chr5:159087579-159087659 ( 37) ATGAGTCA 1 chr14:31713297-31713377 ( 62) ATGAGTCA 1 chr21:45303933-45304013 ( 64) ATGAGTCA 1 chr3:43496824-43496904 ( 12) ATGAGTCA 1 chr5:82265207-82265287 ( 22) ATGAGTCA 1 chr6:158184610-158184690 ( 33) ATGAGTCA 1 chr6:41182711-41182791 ( 69) ATGAGTCA 1 chr11:108211860-10821194 ( 14) ATGAGTCA 1 chr2:80539532-80539612 ( 50) ATGAGTCA 1 chr1:67628827-67628907 ( 23) ATGAGTCA 1 chr16:12707633-12707713 ( 69) CTGACTCA 1 chr5:149489646-149489726 ( 34) CTGACTCA 1 chr6:29813284-29813364 ( 19) CTGACTCA 1 chr2:103281019-103281099 ( 49) CTGACTCA 1 chr22:47169896-47169976 ( 19) CTGACTCA 1 chr6:119580378-119580458 ( 4) CTGACTCA 1 chr3:197304683-197304763 ( 69) CTGACTCA 1 chr10:3797421-3797501 ( 33) CTGACTCA 1 chr15:51892467-51892547 ( 39) CTGACTCA 1 chr16:12706615-12706695 ( 31) CTGAGTCA 1 chr18:33039027-33039107 ( 52) CTGAGTCA 1 chr6:28047834-28047914 ( 20) CTGAGTCA 1 chr8:128872135-128872215 ( 7) CTGAGTCA 1 chr8:80766287-80766367 ( 23) CTGAGTCA 1 chr2:48512244-48512324 ( 28) CTGAGTCA 1 chr14:31500902-31500982 ( 60) CTGAGTCA 1 chr1:31944529-31944609 ( 23) GTGACTCA 1 chr1:154285576-154285656 ( 71) GTGACTCA 1 chr22:40451713-40451793 ( 10) GTGACTCA 1 chr15:63688019-63688099 ( 47) GTGACTCA 1 chr16:1347051-1347131 ( 22) GTGACTCA 1 chr2:236353027-236353107 ( 47) GTGACTCA 1 chr3:14014613-14014693 ( 20) GTGACTCA 1 chr6:87923291-87923371 ( 50) GTGACTCA 1 chr1:39860434-39860514 ( 2) GTGAGTCA 1 chr2:20630833-20630913 ( 66) ATGATTCA 1 chr6:10348175-10348255 ( 10) ATGAATCA 1 chr16:9167027-9167107 ( 19) ATGAATCA 1 chrX:135213383-135213463 ( 1) ATGAATCA 1 chr17:56818530-56818610 ( 46) ATGATTCA 1 chr1:27189399-27189479 ( 70) ATGATTCA 1 chr12:123210726-12321080 ( 21) ATGACTAA 1 chr1:201140085-201140165 ( 28) CTGAGTAA 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif MTGASTCA MEME-3 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 9.63023 E= 1.1e-031 104 37 -59 -1232 -1232 -1232 -1232 207 -1232 -1232 191 -1232 207 -1232 -1232 -1232 -202 81 70 -201 -1232 -1232 -1232 207 -260 190 -1232 -1232 207 -1232 -1232 -1232 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif MTGASTCA MEME-3 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 51 E= 1.1e-031 0.490196 0.333333 0.176471 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.058824 0.450980 0.431373 0.058824 0.000000 0.000000 0.000000 1.000000 0.039216 0.960784 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif MTGASTCA MEME-3 regular expression -------------------------------------------------------------------------------- [AC]TGA[CG]TCA -------------------------------------------------------------------------------- Time 12.15 secs. ******************************************************************************** ******************************************************************************** MOTIF KCTTATCT MEME-4 width = 8 sites = 32 llr = 295 E-value = 2.3e-013 ******************************************************************************** -------------------------------------------------------------------------------- Motif KCTTATCT MEME-4 Description -------------------------------------------------------------------------------- Simplified A ::::a::2 pos.-specific C 28::::a: probability G 4::::::: matrix T 42aa:a:8 bits 2.1 **** 1.9 ***** 1.7 ***** 1.5 ******* Relative 1.2 ******* Entropy 1.0 ******* (13.3 bits) 0.8 ******* 0.6 ******* 0.4 ******** 0.2 ******** 0.0 -------- Multilevel TCTTATCT consensus G sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif KCTTATCT MEME-4 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr9:130841362-130841442 40 1.18e-05 ATAAGGAGCT TCTTATCT ACTTTAAGCT chr17:38673229-38673309 30 1.18e-05 TTTCTGGCCA TCTTATCT CTGTCTTCAA chr11:118482002-11848208 15 1.18e-05 ctccatcttt tcttatct tctccccaca chr6:3348241-3348321 20 1.18e-05 tcactggctc tcttatct cactgcaggc chr11:16381088-16381168 29 1.18e-05 CCTGTCCTTT TCTTATCT TGTCCTTGGT chr12:123235892-12323597 6 1.18e-05 cttcc tcttatct caactgcaca chr6:43905205-43905285 52 2.51e-05 ATCATAGACA GCTTATCT CCTGTGGTCA chr2:18739904-18739984 40 2.51e-05 tgagataaat gcttatct gattgctgac chr22:40451713-40451793 23 2.51e-05 ACTCATTTAA GCTTATCT GTAGGAGCAG chr2:15698279-15698359 44 2.51e-05 taatgctgcc gcttatct gacaggaagt chr3:46534570-46534650 67 2.51e-05 ttctacctct gcttatct ttaaga chr1:26109406-26109486 40 2.51e-05 TCAGTTTCTC GCTTATCT CCCCAGGTTG chr7:133886501-133886581 12 2.51e-05 CTGTAACTCT GCTTATCT CCATGGTCAT chr11:118586753-11858683 50 2.51e-05 taaattaaca gcttatct ttgcaggcgg chr10:79728991-79729071 7 2.51e-05 TAAGTA GCTTATCT TGTACATGAG chr3:197304683-197304763 29 2.51e-05 AGGCTGGGGA GCTTATCT CCTCCAGGTA chr20:44997134-44997214 33 3.80e-05 TCCTAGTTGA CCTTATCT TTGTAATGAC chr22:21195375-21195455 18 3.80e-05 gtctcgaact ccttatct caggtgatac chr3:45008362-45008442 40 3.80e-05 AAGAAAGGTG CCTTATCT TCTGCGGCAC chr5:43197805-43197885 43 3.80e-05 TTCCTTCAGG CCTTATCT CCTTCCAGAT chr4:40310331-40310411 35 6.08e-05 gagtctaggg ttTTATCT TTCTATCACA chr3:156827459-156827539 72 6.08e-05 CTGGCGTCAG TCTTATCA G chr7:135667188-135667268 65 6.08e-05 atgtttaacc ttttatct gttgctat chr2:70312485-70312565 30 6.08e-05 CAGGTGTAGC TCTTATCA GGAAAAGCTG chr19:41129876-41129956 30 6.08e-05 CACTGTGGGC TCTTATCA CTGTACCTGC chr11:46638885-46638965 42 6.08e-05 TCCGTCTTTG TTTTATCT TGAGTAGCTT chr17:48571276-48571356 27 6.08e-05 ctgaaactag ttttatct gatggctact chr10:35703440-35703520 18 8.64e-05 ctattctgtt gcttatca gcaagtcaca chr1:207919904-207919984 47 8.64e-05 ggagctctga gtttatct tgggatctca chr17:76850332-76850412 23 1.11e-04 AAGAGATTCT CCTTATCA TTACCGAGAA chr2:11893772-11893852 36 1.11e-04 AATTCATCAC CCTTATCA ACCGCCGTTA chr6:28448064-28448144 46 1.23e-04 TCTCATTAGA ACTTATCT GCTTTCTGCG -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif KCTTATCT MEME-4 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr9:130841362-130841442 1.2e-05 39_[+4]_33 chr17:38673229-38673309 1.2e-05 29_[+4]_43 chr11:118482002-11848208 1.2e-05 14_[+4]_58 chr6:3348241-3348321 1.2e-05 19_[+4]_53 chr11:16381088-16381168 1.2e-05 28_[+4]_44 chr12:123235892-12323597 1.2e-05 5_[+4]_67 chr6:43905205-43905285 2.5e-05 51_[+4]_21 chr2:18739904-18739984 2.5e-05 39_[+4]_33 chr22:40451713-40451793 2.5e-05 22_[+4]_50 chr2:15698279-15698359 2.5e-05 43_[+4]_29 chr3:46534570-46534650 2.5e-05 66_[+4]_6 chr1:26109406-26109486 2.5e-05 39_[+4]_33 chr7:133886501-133886581 2.5e-05 11_[+4]_61 chr11:118586753-11858683 2.5e-05 49_[+4]_23 chr10:79728991-79729071 2.5e-05 6_[+4]_66 chr3:197304683-197304763 2.5e-05 28_[+4]_44 chr20:44997134-44997214 3.8e-05 32_[+4]_40 chr22:21195375-21195455 3.8e-05 17_[+4]_55 chr3:45008362-45008442 3.8e-05 39_[+4]_33 chr5:43197805-43197885 3.8e-05 42_[+4]_30 chr4:40310331-40310411 6.1e-05 34_[+4]_38 chr3:156827459-156827539 6.1e-05 71_[+4]_1 chr7:135667188-135667268 6.1e-05 64_[+4]_8 chr2:70312485-70312565 6.1e-05 29_[+4]_43 chr19:41129876-41129956 6.1e-05 29_[+4]_43 chr11:46638885-46638965 6.1e-05 41_[+4]_31 chr17:48571276-48571356 6.1e-05 26_[+4]_46 chr10:35703440-35703520 8.6e-05 17_[+4]_55 chr1:207919904-207919984 8.6e-05 46_[+4]_26 chr17:76850332-76850412 0.00011 22_[+4]_50 chr2:11893772-11893852 0.00011 35_[+4]_37 chr6:28448064-28448144 0.00012 45_[+4]_27 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif KCTTATCT MEME-4 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF KCTTATCT width=8 seqs=32 chr9:130841362-130841442 ( 40) TCTTATCT 1 chr17:38673229-38673309 ( 30) TCTTATCT 1 chr11:118482002-11848208 ( 15) TCTTATCT 1 chr6:3348241-3348321 ( 20) TCTTATCT 1 chr11:16381088-16381168 ( 29) TCTTATCT 1 chr12:123235892-12323597 ( 6) TCTTATCT 1 chr6:43905205-43905285 ( 52) GCTTATCT 1 chr2:18739904-18739984 ( 40) GCTTATCT 1 chr22:40451713-40451793 ( 23) GCTTATCT 1 chr2:15698279-15698359 ( 44) GCTTATCT 1 chr3:46534570-46534650 ( 67) GCTTATCT 1 chr1:26109406-26109486 ( 40) GCTTATCT 1 chr7:133886501-133886581 ( 12) GCTTATCT 1 chr11:118586753-11858683 ( 50) GCTTATCT 1 chr10:79728991-79729071 ( 7) GCTTATCT 1 chr3:197304683-197304763 ( 29) GCTTATCT 1 chr20:44997134-44997214 ( 33) CCTTATCT 1 chr22:21195375-21195455 ( 18) CCTTATCT 1 chr3:45008362-45008442 ( 40) CCTTATCT 1 chr5:43197805-43197885 ( 43) CCTTATCT 1 chr4:40310331-40310411 ( 35) TTTTATCT 1 chr3:156827459-156827539 ( 72) TCTTATCA 1 chr7:135667188-135667268 ( 65) TTTTATCT 1 chr2:70312485-70312565 ( 30) TCTTATCA 1 chr19:41129876-41129956 ( 30) TCTTATCA 1 chr11:46638885-46638965 ( 42) TTTTATCT 1 chr17:48571276-48571356 ( 27) TTTTATCT 1 chr10:35703440-35703520 ( 18) GCTTATCA 1 chr1:207919904-207919984 ( 47) GTTTATCT 1 chr17:76850332-76850412 ( 23) CCTTATCA 1 chr2:11893772-11893852 ( 36) CCTTATCA 1 chr6:28448064-28448144 ( 46) ACTTATCT 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif KCTTATCT MEME-4 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 10.8918 E= 2.3e-013 -293 -46 49 77 -1164 171 -1164 -60 -1164 -1164 -1164 207 -1164 -1164 -1164 207 207 -1164 -1164 -1164 -1164 -1164 -1164 207 -1164 196 -1164 -1164 -35 -1164 -1164 177 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif KCTTATCT MEME-4 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 32 E= 2.3e-013 0.031250 0.187500 0.375000 0.406250 0.000000 0.843750 0.000000 0.156250 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 0.187500 0.000000 0.000000 0.812500 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif KCTTATCT MEME-4 regular expression -------------------------------------------------------------------------------- [TG]CTTATCT -------------------------------------------------------------------------------- Time 15.54 secs. ******************************************************************************** ******************************************************************************** MOTIF YYACCTGY MEME-5 width = 8 sites = 38 llr = 307 E-value = 1.6e-001 ******************************************************************************** -------------------------------------------------------------------------------- Motif YYACCTGY MEME-5 Description -------------------------------------------------------------------------------- Simplified A 2:a::::1 pos.-specific C 46:aa::4 probability G ::::::a2 matrix T 44:::a:2 bits 2.1 * * 1.9 ***** 1.7 ***** 1.5 ***** Relative 1.2 ***** Entropy 1.0 ****** (11.6 bits) 0.8 ****** 0.6 ******* 0.4 ******* 0.2 ******** 0.0 -------- Multilevel CCACCTGC consensus TT T sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YYACCTGY MEME-5 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr6:28047834-28047914 6 3.29e-05 cctgg tcacctgc tctgacctga chr11:71159292-71159372 63 3.29e-05 CCTCGGCCCC TCACCTGC GCCCACCTTC chr16:12707633-12707713 55 3.29e-05 gtcaccctgg tcacctgc tgtgtcctga chr5:149489646-149489726 1 3.29e-05 . tcacctgc tttgacctga chr19:11320690-11320770 66 3.29e-05 gtctatcccc tcacctgc ccacctt chr4:2956828-2956908 64 3.29e-05 CCCCCTCTAG TCACCTGC ACGCCACGG chr19:18491276-18491356 31 3.29e-05 TCATCTCTGG CCACCTGC CTGCATCCGC chrX:135213383-135213463 41 6.31e-05 gctgtggtta ctacctgc ctgtgccggt chr6:29813284-29813364 61 6.31e-05 ctcattctga ttacctgc tccaccctga chr1:27995619-27995699 37 6.31e-05 acccgcatct ttacctgc atccttaccc chr1:39860434-39860514 42 6.31e-05 TTAGCGTTAT CTACCTGC CCTTGGAGAG chr20:51040993-51041073 25 6.31e-05 tcacctgtgc ctacctgc actcacctgc chr11:3278834-3278914 41 6.31e-05 cacctatatc ctacctgc atcccaccta chr2:7006508-7006588 13 9.34e-05 GTGCACTCAC TCACCTGT GCACACACTC chr6:28889981-28890061 54 1.37e-04 AATGAGTCAT CTACCTGT CCCTGGTAGG chr22:45127096-45127176 23 1.37e-04 TGTGTGGGTC TTACCTGT GCAGGTCTCC chr1:26595539-26595619 42 1.37e-04 tcacctttaa ttacctgt tcctaactgt chr16:89209032-89209112 25 1.37e-04 aggcacaccc acacCTGC AGACAGAGCc chr7:135667188-135667268 43 1.37e-04 cataaagaag ctacctgt ggagatgttt chr11:16381088-16381168 16 1.37e-04 TTATCTGTGC CTACCTGT CCTTTTCTTA chr12:133006557-13300663 68 1.37e-04 acactggagc acacctgc acaca chr9:127894177-127894257 27 1.37e-04 GAGATAAACA CTACCTGT CTGACGGCTA chr1:1059342-1059422 68 1.37e-04 ctgcgcgcac acacctgc acaca chr2:48512244-48512324 72 1.37e-04 tcacctttag ttacctgt t chr1:1059142-1059222 4 1.37e-04 cac acacctgc acatacacct chr1:59351054-59351134 32 1.85e-04 CTGCTTGGCT CCACCTGG CTCCAACTCT chr8:128872135-128872215 67 1.85e-04 TGTGTCATCT CCACCTGG GTGTGG chr1:233760158-233760238 24 1.85e-04 ACATCTGTct tcacctgg cctcacctat chr19:9969614-9969694 69 1.85e-04 AGGTAGACTC TCACCTGG CTAA chr20:48675986-48676066 46 2.17e-04 aatacaaaaa ttacctgg gcgtggtgtt chr2:175075697-175075777 22 2.17e-04 CTTCCTGGCT CTACCTGG CAGAGGATAG chr7:149388116-149388196 56 2.47e-04 GTGAAATTAG CCACCTGA AAAACTCACC chr11:108211860-10821194 25 2.47e-04 tgagtcatct ccacctga cttacctggt chr17:45352820-45352900 59 2.89e-04 TGCGGCTCAG CTACCTGA GGCTTCCTCT chr2:12318566-12318646 31 2.89e-04 agataactgt ctacctGA GAGATGAAGT chr22:19155952-19156032 61 2.89e-04 TGGTAAACAC ACACCTGT CCGTCCAGGT chr8:1326582-1326662 68 3.19e-04 CATCCTGCAC ACacctgg cctca chr2:8641059-8641139 46 3.49e-04 CAGGTGACGC ACACCTGA GCCCCAGGTA -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YYACCTGY MEME-5 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr6:28047834-28047914 3.3e-05 5_[+5]_67 chr11:71159292-71159372 3.3e-05 62_[+5]_10 chr16:12707633-12707713 3.3e-05 54_[+5]_18 chr5:149489646-149489726 3.3e-05 [+5]_72 chr19:11320690-11320770 3.3e-05 65_[+5]_7 chr4:2956828-2956908 3.3e-05 63_[+5]_9 chr19:18491276-18491356 3.3e-05 30_[+5]_42 chrX:135213383-135213463 6.3e-05 40_[+5]_32 chr6:29813284-29813364 6.3e-05 60_[+5]_12 chr1:27995619-27995699 6.3e-05 36_[+5]_36 chr1:39860434-39860514 6.3e-05 41_[+5]_31 chr20:51040993-51041073 6.3e-05 24_[+5]_48 chr11:3278834-3278914 6.3e-05 40_[+5]_32 chr2:7006508-7006588 9.3e-05 12_[+5]_60 chr6:28889981-28890061 0.00014 53_[+5]_19 chr22:45127096-45127176 0.00014 22_[+5]_50 chr1:26595539-26595619 0.00014 41_[+5]_31 chr16:89209032-89209112 0.00014 24_[+5]_48 chr7:135667188-135667268 0.00014 42_[+5]_30 chr11:16381088-16381168 0.00014 15_[+5]_57 chr12:133006557-13300663 0.00014 67_[+5]_5 chr9:127894177-127894257 0.00014 26_[+5]_46 chr1:1059342-1059422 0.00014 67_[+5]_5 chr2:48512244-48512324 0.00014 71_[+5]_1 chr1:1059142-1059222 0.00014 3_[+5]_69 chr1:59351054-59351134 0.00019 31_[+5]_41 chr8:128872135-128872215 0.00019 66_[+5]_6 chr1:233760158-233760238 0.00019 23_[+5]_49 chr19:9969614-9969694 0.00019 68_[+5]_4 chr20:48675986-48676066 0.00022 45_[+5]_27 chr2:175075697-175075777 0.00022 21_[+5]_51 chr7:149388116-149388196 0.00025 55_[+5]_17 chr11:108211860-10821194 0.00025 24_[+5]_48 chr17:45352820-45352900 0.00029 58_[+5]_14 chr2:12318566-12318646 0.00029 30_[+5]_42 chr22:19155952-19156032 0.00029 60_[+5]_12 chr8:1326582-1326662 0.00032 67_[+5]_5 chr2:8641059-8641139 0.00035 45_[+5]_27 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YYACCTGY MEME-5 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF YYACCTGY width=8 seqs=38 chr6:28047834-28047914 ( 6) TCACCTGC 1 chr11:71159292-71159372 ( 63) TCACCTGC 1 chr16:12707633-12707713 ( 55) TCACCTGC 1 chr5:149489646-149489726 ( 1) TCACCTGC 1 chr19:11320690-11320770 ( 66) TCACCTGC 1 chr4:2956828-2956908 ( 64) TCACCTGC 1 chr19:18491276-18491356 ( 31) CCACCTGC 1 chrX:135213383-135213463 ( 41) CTACCTGC 1 chr6:29813284-29813364 ( 61) TTACCTGC 1 chr1:27995619-27995699 ( 37) TTACCTGC 1 chr1:39860434-39860514 ( 42) CTACCTGC 1 chr20:51040993-51041073 ( 25) CTACCTGC 1 chr11:3278834-3278914 ( 41) CTACCTGC 1 chr2:7006508-7006588 ( 13) TCACCTGT 1 chr6:28889981-28890061 ( 54) CTACCTGT 1 chr22:45127096-45127176 ( 23) TTACCTGT 1 chr1:26595539-26595619 ( 42) TTACCTGT 1 chr16:89209032-89209112 ( 25) ACACCTGC 1 chr7:135667188-135667268 ( 43) CTACCTGT 1 chr11:16381088-16381168 ( 16) CTACCTGT 1 chr12:133006557-13300663 ( 68) ACACCTGC 1 chr9:127894177-127894257 ( 27) CTACCTGT 1 chr1:1059342-1059422 ( 68) ACACCTGC 1 chr2:48512244-48512324 ( 72) TTACCTGT 1 chr1:1059142-1059222 ( 4) ACACCTGC 1 chr1:59351054-59351134 ( 32) CCACCTGG 1 chr8:128872135-128872215 ( 67) CCACCTGG 1 chr1:233760158-233760238 ( 24) TCACCTGG 1 chr19:9969614-9969694 ( 69) TCACCTGG 1 chr20:48675986-48676066 ( 46) TTACCTGG 1 chr2:175075697-175075777 ( 22) CTACCTGG 1 chr7:149388116-149388196 ( 56) CCACCTGA 1 chr11:108211860-10821194 ( 25) CCACCTGA 1 chr17:45352820-45352900 ( 59) CTACCTGA 1 chr2:12318566-12318646 ( 31) CTACCTGA 1 chr22:19155952-19156032 ( 61) ACACCTGT 1 chr8:1326582-1326662 ( 68) ACACCTGG 1 chr2:8641059-8641139 ( 46) ACACCTGA 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YYACCTGY MEME-5 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 10.7218 E= 1.6e-001 -37 71 -1189 73 -1189 110 -1189 91 207 -1189 -1189 -1189 -1189 196 -1189 -1189 -1189 196 -1189 -1189 -1189 -1189 -1189 207 -1189 -1189 191 -1189 -86 79 -53 0 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YYACCTGY MEME-5 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 38 E= 1.6e-001 0.184211 0.421053 0.000000 0.394737 0.000000 0.552632 0.000000 0.447368 1.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.131579 0.447368 0.184211 0.236842 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YYACCTGY MEME-5 regular expression -------------------------------------------------------------------------------- [CT][CT]ACCTG[CT] -------------------------------------------------------------------------------- Time 18.89 secs. ******************************************************************************** ******************************************************************************** SUMMARY OF MOTIFS ******************************************************************************** -------------------------------------------------------------------------------- Combined block diagrams: non-overlapping sites with p-value < 0.0001 -------------------------------------------------------------------------------- SEQUENCE NAME COMBINED P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr11:3278834-3278914 5.67e-02 18_[+5(6.31e-05)]_14_[+5(6.31e-05)]_\ 14_[+5(6.31e-05)]_10 chr12:48137965-48138045 7.03e-04 38_[+1(6.51e-05)]_34 chr6:87923291-87923371 8.59e-03 36_[+1(4.96e-05)]_5_[+3(7.17e-05)]_\ 7_[+1(4.96e-05)]_8 chr17:27564534-27564614 6.44e-02 80 chr6:126264341-126264421 1.55e-01 80 chr10:75692212-75692292 7.79e-06 15_[+2(7.86e-05)]_4_[+3(7.17e-05)]_\ 31_[+3(1.34e-05)]_6 chr3:14014613-14014693 9.07e-03 6_[+1(4.96e-05)]_5_[+3(7.17e-05)]_8_\ [+1(4.96e-05)]_4_[+3(7.17e-05)]_25 chr20:51040993-51041073 1.08e-03 13_[+2(1.58e-05)]_3_[+5(6.31e-05)]_\ 1_[+2(1.58e-05)]_3_[+5(6.31e-05)]_11_[+2(1.58e-05)]_9 chr17:48571276-48571356 3.68e-03 26_[+4(6.08e-05)]_46 chr3:119414443-119414523 8.92e-02 80 chr15:51892467-51892547 5.82e-04 38_[+3(4.18e-05)]_34 chr8:144536449-144536529 2.70e-02 44_[+1(3.28e-05)]_28 chr22:38003240-38003320 5.57e-02 16_[+1(1.73e-05)]_56 chr1:1059142-1059222 3.44e-03 2_[+2(3.16e-05)]_26_[+2(3.16e-05)]_\ 4_[+2(3.16e-05)]_24 chr2:8641059-8641139 1.19e-04 13_[+2(3.16e-05)]_14_[+1(4.96e-05)]_\ 1_[+2(3.16e-05)]_14_[+1(4.96e-05)]_6 chr2:7006508-7006588 5.81e-04 11_[+2(1.58e-05)]_24_[+2(1.58e-05)]_\ 29 chr10:3797421-3797501 1.56e-04 2_[+2(9.31e-05)]_22_[+3(4.18e-05)]_\ 40 chr22:19155952-19156032 4.22e-05 2_[+2(3.16e-05)]_25_[+2(1.58e-05)]_\ 16_[+2(3.16e-05)]_13 chr1:39860434-39860514 3.73e-05 1_[+3(8.72e-05)]_32_[+5(6.31e-05)]_\ 31 chr14:31500902-31500982 2.74e-03 59_[+3(5.67e-05)]_13 chr19:9969614-9969694 4.02e-04 4_[+2(1.58e-05)]_13_[+2(1.58e-05)]_\ 34_[+2(1.58e-05)]_5 chr3:197304683-197304763 6.43e-05 28_[+4(2.51e-05)]_32_[+3(4.18e-05)]_\ 4 chr1:67628827-67628907 1.82e-03 22_[+3(2.72e-05)]_23_[+3(7.17e-05)]_\ 19 chr2:80539532-80539612 5.15e-03 8_[+1(4.96e-05)]_5_[+3(7.17e-05)]_8_\ [+1(4.96e-05)]_4_[+3(2.72e-05)]_23 chr1:89990725-89990805 7.55e-01 80 chr19:18491276-18491356 5.59e-03 30_[+5(3.29e-05)]_42 chr2:48512244-48512324 5.48e-05 13_[+5(3.29e-05)]_6_[+3(5.67e-05)]_\ 45 chr11:93305495-93305575 4.45e-01 80 chr12:123235892-12323597 1.57e-04 5_[+4(1.18e-05)]_67 chr16:87495162-87495242 9.07e-03 80 chr1:233760158-233760238 2.19e-03 52_[+2(1.58e-05)]_12_[+2(1.58e-05)] chr19:54676824-54676904 9.42e-03 34_[+1(6.51e-05)]_38 chr5:75698261-75698341 4.07e-01 80 chr19:45594979-45595059 9.67e-01 80 chr16:1543432-1543512 6.23e-01 80 chr10:79728991-79729071 1.31e-04 6_[+4(2.51e-05)]_66 chr5:43197805-43197885 2.01e-06 20_[+2(3.16e-05)]_14_[+4(3.80e-05)]_\ 30 chr15:91576458-91576538 6.77e-02 22_[+1(4.96e-05)]_50 chr10:115614163-11561424 9.97e-01 80 chr4:54457816-54457896 8.63e-04 80 chr11:108211860-10821194 1.10e-04 13_[+3(2.72e-05)]_11_[+2(7.86e-05)]_\ 40 chr16:71460637-71460717 2.23e-03 35_[+2(9.31e-05)]_37 chrX:153602046-153602126 1.67e-01 80 chr6:119580378-119580458 9.35e-05 3_[+3(4.18e-05)]_12_[+5(6.31e-05)]_\ 49 chr2:236353027-236353107 3.95e-03 33_[+1(4.96e-05)]_5_[+3(7.17e-05)]_\ 7_[+1(4.96e-05)]_11 chr2:109237747-109237827 8.94e-01 80 chr4:2956828-2956908 4.90e-03 7_[+5(3.29e-05)]_19_[+5(3.29e-05)]_\ 21_[+5(3.29e-05)]_9 chr22:47169896-47169976 2.26e-03 18_[+3(4.18e-05)]_54 chr19:11320690-11320770 7.90e-04 [+2(1.58e-05)]_8_[+2(1.58e-05)]_8_\ [+2(1.58e-05)]_24_[+2(1.58e-05)]_8 chr3:137906238-137906318 4.62e-01 80 chr21:37525427-37525507 3.72e-04 51_[+2(3.16e-05)]_21 chr1:1059342-1059422 9.00e-03 7_[+2(3.16e-05)]_13_[+2(3.16e-05)]_\ 4_[+2(3.16e-05)]_18_[+2(3.16e-05)]_6 chr19:14328365-14328445 6.48e-02 17_[+1(1.73e-05)]_55 chr6:41182711-41182791 4.18e-03 68_[+3(2.72e-05)]_4 chr9:127894177-127894257 3.80e-02 80 chr12:133006557-13300663 1.26e-02 6_[+2(3.16e-05)]_2_[+2(3.16e-05)]_\ 12_[+2(3.16e-05)]_2_[+2(3.16e-05)]_12_[+2(3.16e-05)]_6 chr15:78857518-78857598 2.51e-01 80 chr6:158184610-158184690 4.51e-05 32_[+3(2.72e-05)]_40 chr10:74036359-74036439 2.15e-02 10_[+1(1.73e-05)]_62 chr3:45008362-45008442 4.22e-02 39_[+4(3.80e-05)]_33 chr15:74683427-74683507 9.65e-02 80 chr11:46638885-46638965 1.06e-01 41_[+4(6.08e-05)]_31 chr2:171319278-171319358 2.28e-01 80 chr2:27184793-27184873 6.74e-02 80 chr7:127228953-127229033 3.59e-02 80 chr1:207919904-207919984 2.56e-02 46_[+4(8.64e-05)]_26 chr11:33342671-33342751 6.81e-02 80 chr1:22587458-22587538 1.87e-01 80 chr10:61895010-61895090 1.05e-03 67_[+2(1.58e-05)]_5 chr19:42429554-42429634 2.84e-01 80 chr9:116327691-116327771 2.60e-01 80 chr16:90098699-90098779 1.55e-01 54_[+1(1.73e-05)]_18 chr11:118586753-11858683 1.23e-02 49_[+4(2.51e-05)]_23 chr4:186240032-186240112 3.19e-01 80 chr1:202452648-202452728 3.05e-03 9_[+1(4.96e-05)]_5_[+3(1.34e-05)]_8_\ [+1(3.28e-05)]_34 chr1:27189399-27189479 2.19e-03 80 chr16:1347051-1347131 1.31e-02 18_[+1(4.96e-05)]_21_[+1(4.96e-05)]_\ 3_[+3(7.17e-05)]_14 chr1:160991101-160991181 7.20e-02 80 chr1:27286869-27286949 5.31e-05 25_[+2(1.58e-05)]_5_[+1(1.73e-05)]_\ 34 chr19:45057128-45057208 3.00e-03 31_[+1(1.73e-05)]_41 chr9:138863950-138864030 2.85e-01 80 chr1:209979407-209979487 1.69e-04 42_[+5(6.31e-05)]_30 chr19:39900163-39900243 5.66e-04 47_[+1(1.73e-05)]_25 chr6:136871667-136871747 4.96e-01 80 chr6:5231066-5231146 1.17e-01 80 chr6:106760941-106761021 3.90e-01 80 chr1:168414959-168415039 3.08e-02 80 chr5:82265207-82265287 1.36e-02 21_[+3(2.72e-05)]_9_[+3(2.72e-05)]_\ 20_[+3(2.72e-05)]_6 chr16:11188054-11188134 2.88e-03 23_[+1(4.96e-05)]_49 chr14:100017783-10001786 3.32e-02 19_[+1(6.51e-05)]_40_[+1(1.73e-05)]_\ 5 chr2:11893772-11893852 7.12e-03 80 chr8:80766287-80766367 1.37e-02 22_[+3(5.67e-05)]_50 chr13:37574769-37574849 7.87e-01 80 chr16:84173162-84173242 7.54e-02 80 chr16:9144511-9144591 8.34e-03 32_[+1(1.73e-05)]_2_[+1(1.73e-05)]_\ 30 chr9:96974532-96974612 6.67e-02 80 chr2:12318566-12318646 1.46e-02 80 chr17:76356860-76356940 4.64e-01 80 chr12:123210726-12321080 5.15e-03 80 chr16:2193559-2193639 1.81e-02 40_[+2(7.86e-05)]_32 chr1:15364802-15364882 6.88e-02 80 chr6:166795483-166795563 3.97e-04 39_[+2(3.16e-05)]_8_[+1(4.96e-05)]_\ 17 chr1:27995619-27995699 2.74e-03 12_[+5(6.31e-05)]_16_[+5(6.31e-05)]_\ 16_[+5(6.31e-05)]_12 chr12:93963858-93963938 9.18e-01 80 chr11:16381088-16381168 7.93e-04 28_[+4(1.18e-05)]_44 chr8:135725184-135725264 5.71e-01 80 chr17:45352820-45352900 1.93e-03 80 chr7:133886501-133886581 1.09e-02 11_[+4(2.51e-05)]_61 chr11:10604355-10604435 1.53e-04 17_[+2(3.16e-05)]_55 chr1:26109406-26109486 7.21e-02 39_[+4(2.51e-05)]_33 chr17:38804171-38804251 3.33e-01 80 chr1:165812122-165812202 5.51e-02 80 chr2:103281019-103281099 3.24e-04 48_[+3(4.18e-05)]_24 chr17:56818530-56818610 5.13e-02 80 chr6:109509244-109509324 2.14e-02 25_[+1(6.51e-05)]_47 chr8:145277514-145277594 3.04e-01 80 chr19:41129876-41129956 7.81e-04 29_[+4(6.08e-05)]_43 chr7:120778429-120778509 1.18e-01 80 chr3:43496824-43496904 4.01e-02 11_[+3(2.72e-05)]_61 chr10:74021490-74021570 1.66e-01 80 chr3:46534570-46534650 7.87e-05 66_[+4(2.51e-05)]_6 chr20:48629239-48629319 7.50e-03 80 chr22:21195375-21195455 9.85e-05 17_[+4(3.80e-05)]_[+1(3.28e-05)]_47 chr21:45303933-45304013 2.90e-04 63_[+3(2.72e-05)]_9 chr6:29813284-29813364 5.64e-05 4_[+5(6.31e-05)]_6_[+3(4.18e-05)]_6_\ [+5(3.29e-05)]_6_[+3(4.18e-05)]_6_[+5(6.31e-05)]_12 chr12:4647732-4647812 7.18e-02 80 chr6:28448064-28448144 2.14e-03 80 chr3:47523325-47523405 3.93e-03 57_[+2(9.31e-05)]_15 chr2:70312485-70312565 4.25e-03 29_[+4(6.08e-05)]_43 chr1:201894422-201894502 2.44e-02 80 chr17:76850332-76850412 1.51e-01 80 chr15:63688019-63688099 2.65e-02 46_[+3(7.17e-05)]_26 chr6:3348241-3348321 4.01e-04 19_[+4(1.18e-05)]_53 chr17:16302084-16302164 2.15e-05 27_[+3(1.34e-05)]_45 chr17:34901352-34901432 8.26e-01 80 chr19:48151704-48151784 1.24e-02 80 chr2:15698279-15698359 2.21e-03 43_[+4(2.51e-05)]_29 chr7:135667188-135667268 6.95e-04 64_[+4(6.08e-05)]_8 chr17:8340065-8340145 8.97e-02 80 chr5:149489646-149489726 4.60e-05 [+5(3.29e-05)]_11_[+5(3.29e-05)]_6_\ [+3(4.18e-05)]_7_[+5(9.34e-05)]_24 chr6:157849965-157850045 7.92e-01 80 chr22:40451713-40451793 1.06e-06 9_[+3(7.17e-05)]_5_[+4(2.51e-05)]_\ 35_[+2(9.31e-05)]_7 chr6:117857561-117857641 8.56e-02 80 chr1:24741990-24742070 6.09e-01 80 chr6:135327832-135327912 2.96e-02 48_[+1(1.73e-05)]_24 chr7:137652116-137652196 2.50e-02 80 chr11:123613252-12361333 4.22e-01 80 chr19:50637549-50637629 3.14e-01 80 chr6:28459522-28459602 1.19e-02 80 chr11:73495430-73495510 3.23e-02 80 chr16:89209032-89209112 1.02e-03 23_[+2(3.16e-05)]_10_[+2(3.16e-05)]_\ 10_[+2(1.58e-05)]_13 chr20:44997134-44997214 8.96e-05 13_[+3(1.34e-05)]_11_[+4(3.80e-05)]_\ 40 chr7:129076316-129076396 1.38e-01 80 chr2:175075697-175075777 4.95e-02 80 chr5:138088737-138088817 1.31e-01 80 chr5:43067062-43067142 3.45e-01 80 chr1:201140085-201140165 5.91e-05 80 chr10:3852423-3852503 1.16e-02 59_[+1(1.73e-05)]_13 chr7:140188215-140188295 2.78e-02 80 chr19:39174325-39174405 7.62e-01 80 chr16:85644517-85644597 2.91e-01 80 chr14:31713297-31713377 1.38e-02 61_[+3(2.72e-05)]_11 chr3:99536510-99536590 5.67e-01 80 chr5:159087579-159087659 4.55e-02 36_[+3(2.72e-05)]_36 chr20:49347826-49347906 5.06e-01 80 chr1:26595539-26595619 5.56e-04 12_[+5(3.29e-05)]_60 chr11:118482002-11848208 6.06e-03 14_[+4(1.18e-05)]_17_[+4(3.80e-05)]_\ 33 chrX:135213383-135213463 1.32e-03 40_[+5(6.31e-05)]_32 chr11:118801020-11880110 3.06e-02 35_[+1(1.73e-05)]_37 chr8:1326582-1326662 3.67e-03 8_[+2(3.16e-05)]_2_[+2(1.58e-05)]_\ 11_[+2(3.16e-05)]_21_[+2(3.16e-05)]_6 chr15:66263566-66263646 5.51e-01 80 chr4:38623027-38623107 9.46e-02 80 chr7:72299827-72299907 5.01e-01 80 chr15:65545164-65545244 1.19e-03 37_[+2(3.16e-05)]_35 chr5:140090597-140090677 1.42e-04 10_[+1(4.96e-05)]_28_[+2(3.16e-05)]_\ 26 chr8:131012378-131012458 2.11e-04 80 chr16:12707633-12707713 4.21e-05 26_[+5(3.29e-05)]_6_[+3(5.67e-05)]_\ 6_[+5(3.29e-05)]_6_[+3(4.18e-05)]_4 chr21:37630186-37630266 9.95e-01 80 chr10:135203779-13520385 2.27e-04 37_[+2(3.16e-05)]_35 chr17:38673229-38673309 2.19e-04 29_[+4(1.18e-05)]_32_[+1(6.51e-05)]_\ 3 chr8:128872135-128872215 1.08e-03 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chr8:96224824-96224904 6.48e-01 80 chr6:10348175-10348255 3.69e-02 80 chr9:135854199-135854279 3.64e-02 26_[+1(1.73e-05)]_46 chr5:149088704-149088784 2.32e-01 80 chr17:900249-900329 6.25e-01 80 chr3:45133898-45133978 1.20e-02 80 chr13:46949046-46949126 1.57e-01 80 chr18:33039027-33039107 3.86e-03 51_[+3(5.67e-05)]_21 chr1:3773891-3773971 5.73e-03 80 chr1:100820668-100820748 2.20e-01 80 chr3:156827459-156827539 4.26e-03 71_[+4(6.08e-05)]_1 chr17:27621394-27621474 9.59e-01 80 chr16:11295808-11295888 3.10e-04 35_[+1(4.96e-05)]_12_[+2(3.16e-05)]_\ 17 chr14:69658230-69658310 2.42e-01 80 chr10:50746791-50746871 5.36e-02 7_[+1(1.73e-05)]_25_[+1(1.73e-05)]_\ 32 chr6:34294991-34295071 2.77e-05 51_[+2(1.58e-05)]_21 chr6:13864177-13864257 4.53e-01 80 chr15:90756903-90756983 4.05e-01 80 chr7:149388116-149388196 6.19e-02 80 chr6:43905205-43905285 5.74e-06 51_[+4(2.51e-05)]_10_[+2(1.58e-05)]_\ 3 chr16:12706615-12706695 1.79e-04 30_[+3(5.67e-05)]_7_[+5(6.31e-05)]_\ 16_[+3(8.72e-05)]_3 chr6:161736529-161736609 1.08e-02 17_[+3(2.72e-05)]_20_[+3(2.72e-05)]_\ 27 chr17:76134096-76134176 7.90e-01 80 chr2:20630833-20630913 2.44e-02 80 chr1:52088302-52088382 3.97e-02 80 chr2:68518540-68518620 6.69e-02 80 chr4:40310331-40310411 2.17e-06 11_[+1(1.73e-05)]_15_[+4(6.08e-05)]_\ 6_[+2(3.16e-05)]_24 chr20:48675986-48676066 1.15e-02 64_[+2(3.16e-05)]_8 -------------------------------------------------------------------------------- ******************************************************************************** ******************************************************************************** Stopped because requested number of motifs (5) found. ******************************************************************************** CPU: c22n08.farnam.hpc.yale.internal ********************************************************************************