******************************************************************************** MEME - Motif discovery tool ******************************************************************************** MEME version 5.3.3 (Release date: Sun Feb 7 15:39:52 2021 -0800) For further information on how to interpret these results please access https://meme-suite.org/meme. To get a copy of the MEME Suite software please access https://meme-suite.org. ******************************************************************************** ******************************************************************************** REFERENCE ******************************************************************************** If you use this program in your research, please cite: Timothy L. Bailey and Charles Elkan, "Fitting a mixture model by expectation maximization to discover motifs in biopolymers", Proceedings of the Second International Conference on Intelligent Systems for Molecular Biology, pp. 28-36, AAAI Press, Menlo Park, California, 1994. ******************************************************************************** ******************************************************************************** TRAINING SET ******************************************************************************** PRIMARY SEQUENCES= ../result/final_prediction/K562/fasta/RankLinear0.6_40/ZBTB7A.fasta CONTROL SEQUENCES= --none-- ALPHABET= ACGT Sequence name Weight Length Sequence name Weight Length ------------- ------ ------ ------------- ------ ------ chr19:45752122-45752202 1.0000 80 chr19:35605662-35605742 1.0000 80 chr19:822111-822191 1.0000 80 chr19:45287798-45287878 1.0000 80 chr1:33338330-33338410 1.0000 80 chr9:130705245-130705325 1.0000 80 chr19:4267819-4267899 1.0000 80 chr12:30848438-30848518 1.0000 80 chr16:3011946-3012026 1.0000 80 chr11:2951697-2951777 1.0000 80 chr1:1951115-1951195 1.0000 80 chr6:43726401-43726481 1.0000 80 chr5:180594972-180595052 1.0000 80 chr20:61071648-61071728 1.0000 80 chr9:140190032-140190112 1.0000 80 chr17:38242884-38242964 1.0000 80 chr11:63688711-63688791 1.0000 80 chr3:13696967-13697047 1.0000 80 chr7:5230248-5230328 1.0000 80 chr10:97804021-97804101 1.0000 80 chr19:17496858-17496938 1.0000 80 chr15:79103977-79104057 1.0000 80 chr6:131384430-131384510 1.0000 80 chr2:139191906-139191986 1.0000 80 chr19:39467328-39467408 1.0000 80 chr7:134379240-134379320 1.0000 80 chr11:63535768-63535848 1.0000 80 chr19:1001742-1001822 1.0000 80 chr19:46142543-46142623 1.0000 80 chr8:134581937-134582017 1.0000 80 chr11:69616491-69616571 1.0000 80 chr19:39226706-39226786 1.0000 80 chr10:134266806-13426688 1.0000 80 chr17:47074616-47074696 1.0000 80 chr9:101867127-101867207 1.0000 80 chr7:87505125-87505205 1.0000 80 chr17:78955227-78955307 1.0000 80 chr10:73407451-73407531 1.0000 80 chr22:42322223-42322303 1.0000 80 chr1:156023737-156023817 1.0000 80 chr7:77326387-77326467 1.0000 80 chrX:39969131-39969211 1.0000 80 chr19:14169951-14170031 1.0000 80 chr1:1532718-1532798 1.0000 80 chr2:238384132-238384212 1.0000 80 chrX:39964421-39964501 1.0000 80 chr21:43298823-43298903 1.0000 80 chr20:52210676-52210756 1.0000 80 chr19:14143122-14143202 1.0000 80 chr16:3068224-3068304 1.0000 80 chr10:3088091-3088171 1.0000 80 chr17:35850299-35850379 1.0000 80 chr3:53230114-53230194 1.0000 80 chr7:100184467-100184547 1.0000 80 chr11:2216344-2216424 1.0000 80 chr1:84543557-84543637 1.0000 80 chr17:1531615-1531695 1.0000 80 chr19:14586206-14586286 1.0000 80 chr1:156355485-156355565 1.0000 80 chr16:85325254-85325334 1.0000 80 chr17:79935770-79935850 1.0000 80 chr17:40610727-40610807 1.0000 80 chr1:145588636-145588716 1.0000 80 chr12:2955200-2955280 1.0000 80 chr17:8649341-8649421 1.0000 80 chr10:73468128-73468208 1.0000 80 chr3:128216824-128216904 1.0000 80 chr17:40115174-40115254 1.0000 80 chr6:29596536-29596616 1.0000 80 chr14:75762885-75762965 1.0000 80 chr4:141174431-141174511 1.0000 80 chr16:89985130-89985210 1.0000 80 chr7:98476151-98476231 1.0000 80 chr13:27746262-27746342 1.0000 80 chr7:1704418-1704498 1.0000 80 chr2:61922178-61922258 1.0000 80 chr5:79378789-79378869 1.0000 80 chr2:64880477-64880557 1.0000 80 chr1:15757715-15757795 1.0000 80 chr1:39283944-39284024 1.0000 80 chr3:99595083-99595163 1.0000 80 chr15:37393999-37394079 1.0000 80 chr17:43209414-43209494 1.0000 80 chr16:30933075-30933155 1.0000 80 chr19:3358741-3358821 1.0000 80 chr3:196756700-196756780 1.0000 80 chr20:62733500-62733580 1.0000 80 chr11:63684044-63684124 1.0000 80 chr9:132998589-132998669 1.0000 80 chr19:14590977-14591057 1.0000 80 chr19:1672161-1672241 1.0000 80 chrX:1573182-1573262 1.0000 80 chr9:32551109-32551189 1.0000 80 chr19:1401578-1401658 1.0000 80 chr2:113239527-113239607 1.0000 80 chr5:172199060-172199140 1.0000 80 chr6:99872724-99872804 1.0000 80 chr11:2913451-2913531 1.0000 80 chr2:30370794-30370874 1.0000 80 chr12:1772026-1772106 1.0000 80 chr19:13274008-13274088 1.0000 80 chr17:55055275-55055355 1.0000 80 chr16:85286971-85287051 1.0000 80 chr2:47499674-47499754 1.0000 80 chr10:82295663-82295743 1.0000 80 chr2:106020410-106020490 1.0000 80 chr2:20442148-20442228 1.0000 80 chr19:11314648-11314728 1.0000 80 chr19:17650077-17650157 1.0000 80 chr1:23543402-23543482 1.0000 80 chr22:19953738-19953818 1.0000 80 chr5:133332512-133332592 1.0000 80 chr14:23479464-23479544 1.0000 80 chr14:105266680-10526676 1.0000 80 chr22:31481295-31481375 1.0000 80 chrX:131119625-131119705 1.0000 80 chr8:143751085-143751165 1.0000 80 chr7:100492622-100492702 1.0000 80 chr19:1194695-1194775 1.0000 80 chr17:37331334-37331414 1.0000 80 chr16:66638797-66638877 1.0000 80 chr6:13710993-13711073 1.0000 80 chr9:101077907-101077987 1.0000 80 chr10:977994-978074 1.0000 80 chr11:64512683-64512763 1.0000 80 chr2:239335594-239335674 1.0000 80 chr9:139566242-139566322 1.0000 80 chr19:18169393-18169473 1.0000 80 chr7:101458883-101458963 1.0000 80 chr7:116503370-116503450 1.0000 80 chr7:101054689-101054769 1.0000 80 chr19:49399626-49399706 1.0000 80 chr19:34286322-34286402 1.0000 80 chr1:1003638-1003718 1.0000 80 chr9:77386011-77386091 1.0000 80 chr11:65083122-65083202 1.0000 80 chr19:12949124-12949204 1.0000 80 chr19:52193207-52193287 1.0000 80 chr17:30469318-30469398 1.0000 80 chr6:112364993-112365073 1.0000 80 chr10:76868586-76868666 1.0000 80 chr7:157092599-157092679 1.0000 80 chr9:114937612-114937692 1.0000 80 chr7:23511029-23511109 1.0000 80 chr7:14029418-14029498 1.0000 80 chr4:1750540-1750620 1.0000 80 chr17:27071433-27071513 1.0000 80 chr1:26946858-26946938 1.0000 80 chr19:18526032-18526112 1.0000 80 chr5:139077406-139077486 1.0000 80 chr11:46141402-46141482 1.0000 80 chr19:56904552-56904632 1.0000 80 chr11:64948448-64948528 1.0000 80 chr6:158244870-158244950 1.0000 80 chr7:5465579-5465659 1.0000 80 chr19:791839-791919 1.0000 80 chr22:38852088-38852168 1.0000 80 chr11:62324209-62324289 1.0000 80 chr22:30821674-30821754 1.0000 80 chr14:69618388-69618468 1.0000 80 chr1:155053522-155053602 1.0000 80 chr1:11796623-11796703 1.0000 80 chr19:4067608-4067688 1.0000 80 chr5:76787760-76787840 1.0000 80 chr4:183727576-183727656 1.0000 80 chr16:230365-230445 1.0000 80 chr1:153957945-153958025 1.0000 80 chr14:102983342-10298342 1.0000 80 chr19:45931064-45931144 1.0000 80 chr19:11200938-11201018 1.0000 80 chr19:1267156-1267236 1.0000 80 chr5:76011849-76011929 1.0000 80 chr7:148396941-148397021 1.0000 80 chr10:25241770-25241850 1.0000 80 chr7:6677450-6677530 1.0000 80 chr19:954862-954942 1.0000 80 chr2:25599736-25599816 1.0000 80 chr19:17403187-17403267 1.0000 80 chr16:28502795-28502875 1.0000 80 chr1:41826907-41826987 1.0000 80 chr15:41166012-41166092 1.0000 80 chr4:184020297-184020377 1.0000 80 chr1:919692-919772 1.0000 80 chr16:90085990-90086070 1.0000 80 chr11:335842-335922 1.0000 80 chr2:198669846-198669926 1.0000 80 chr16:30389628-30389708 1.0000 80 chr4:1580984-1581064 1.0000 80 chr11:47421643-47421723 1.0000 80 chr12:122241354-12224143 1.0000 80 chr15:78423878-78423958 1.0000 80 chr5:71616462-71616542 1.0000 80 chr8:21924443-21924523 1.0000 80 chr16:57126886-57126966 1.0000 80 chr1:206837638-206837718 1.0000 80 chr18:19284242-19284322 1.0000 80 chr20:36849592-36849672 1.0000 80 chr3:185541042-185541122 1.0000 80 chr11:65185728-65185808 1.0000 80 chrX:153031844-153031924 1.0000 80 chr19:1767516-1767596 1.0000 80 chr20:30795103-30795183 1.0000 80 chr7:86689107-86689187 1.0000 80 chr22:39915990-39916070 1.0000 80 chr4:6722096-6722176 1.0000 80 chr17:27921268-27921348 1.0000 80 chr6:32936690-32936770 1.0000 80 chr2:209119094-209119174 1.0000 80 chr1:33207191-33207271 1.0000 80 chr1:145585483-145585563 1.0000 80 chr12:56652205-56652285 1.0000 80 chr13:77904013-77904093 1.0000 80 chr4:6894220-6894300 1.0000 80 chr15:40763076-40763156 1.0000 80 chr16:1463771-1463851 1.0000 80 chr1:150521703-150521783 1.0000 80 chr2:176944716-176944796 1.0000 80 chr9:19230269-19230349 1.0000 80 chr19:7990124-7990204 1.0000 80 chr16:475510-475590 1.0000 80 chr20:48330532-48330612 1.0000 80 chr8:141646112-141646192 1.0000 80 chr19:506913-506993 1.0000 80 chr12:56320876-56320956 1.0000 80 chr22:38198362-38198442 1.0000 80 chr1:54872385-54872465 1.0000 80 chr10:81205490-81205570 1.0000 80 chrX:153637746-153637826 1.0000 80 chr19:3307484-3307564 1.0000 80 chr10:75757476-75757556 1.0000 80 chr1:52195682-52195762 1.0000 80 chr19:14542902-14542982 1.0000 80 chr17:49244569-49244649 1.0000 80 chr17:36762759-36762839 1.0000 80 chr12:48206728-48206808 1.0000 80 chr12:111847777-11184785 1.0000 80 chr17:71228778-71228858 1.0000 80 chr4:184427150-184427230 1.0000 80 chr22:19706543-19706623 1.0000 80 chr9:115096046-115096126 1.0000 80 chr17:73852091-73852171 1.0000 80 chr17:40826271-40826351 1.0000 80 chr1:19734335-19734415 1.0000 80 chr17:46599577-46599657 1.0000 80 chr12:72332629-72332709 1.0000 80 chr4:128802409-128802489 1.0000 80 chr9:129622565-129622645 1.0000 80 chr3:57993942-57994022 1.0000 80 chr19:917844-917924 1.0000 80 chr19:18705233-18705313 1.0000 80 ******************************************************************************** ******************************************************************************** COMMAND LINE SUMMARY ******************************************************************************** This information can also be useful in the event you wish to report a problem with the MEME software. command: meme -oc ../result/final_prediction/K562/inference_raw/MEME/RankLinear0.6_40_ZBTB7A/ -dna -nmotifs 5 -w 8 -maxsize 250000 -nostatus ../result/final_prediction/K562/fasta/RankLinear0.6_40/ZBTB7A.fasta model: mod= zoops nmotifs= 5 evt= inf objective function: em= E-value of product of p-values starts= E-value of product of p-values strands: + width: minw= 8 maxw= 8 nsites: minsites= 2 maxsites= 250 wnsites= 0.8 theta: spmap= uni spfuzz= 0.5 em: prior= dirichlet b= 0.01 maxiter= 50 distance= 1e-05 trim: wg= 11 ws= 1 endgaps= yes data: n= 20000 N= 250 sample: seed= 0 hsfrac= 0 searchsize= 20000 norand= no csites= 1000 Letter frequencies in dataset: A 0.13 C 0.365 G 0.368 T 0.137 Background letter frequencies (from file dataset with add-one prior applied): A 0.13 C 0.365 G 0.368 T 0.137 Background model order: 0 ******************************************************************************** ******************************************************************************** MOTIF GVGMCCCC MEME-1 width = 8 sites = 155 llr = 959 E-value = 2.1e-031 ******************************************************************************** -------------------------------------------------------------------------------- Motif GVGMCCCC MEME-1 Description -------------------------------------------------------------------------------- Simplified A 24:7::1: pos.-specific C 23:3aa97 probability G 63a::::: matrix T :::::::3 bits 2.9 2.6 2.4 2.1 Relative 1.8 Entropy 1.5 **** (8.9 bits) 1.2 ***** 0.9 ****** 0.6 ******* 0.3 ******** 0.0 -------- Multilevel GAGACCCC consensus C C T sequence G -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GVGMCCCC MEME-1 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr1:19734335-19734415 17 5.59e-05 AGGAGGGGGA GAGACCCT CACCAGGGCG chr10:75757476-75757556 25 5.59e-05 TTGAGGTGAG GAGACCCC GCCCCGCTGA chrX:153637746-153637826 54 5.59e-05 GTGCCTGAGT GAGACCCC GAGCTTCGCT chr19:7990124-7990204 11 5.59e-05 ccggcccTCT GAGACCCC GGCGCAGGGC chr22:39915990-39916070 53 5.59e-05 GCAGCGACCC GAGACCCC AACCCTTCCC chr2:25599736-25599816 53 5.59e-05 CCGCGGCGCA GAGACCCT CCCGCCCTCT chr19:1267156-1267236 51 5.59e-05 CCAGCCGCCT GAGACCCC CGGTGGGGAC chr1:153957945-153958025 27 5.59e-05 GGCTGACTCA GAGACCCC AAAAGTCCCC chr19:56904552-56904632 18 5.59e-05 CAGGGGGTCG GAGACCCC TGCGCACCCA chr11:65083122-65083202 34 5.59e-05 AGGGGCGCTG GAGACCCC GGTGCGCTCT chr5:133332512-133332592 56 5.59e-05 GGGAGTTGGG GAGACCCT CAACTAGCAA chr13:27746262-27746342 40 5.59e-05 CGGGGACCCA GAGACCCC CGCGTAGGAA chr4:141174431-141174511 15 5.59e-05 tgggggcggC GAGACCCC GGCTCTGGGC chr17:40115174-40115254 53 5.59e-05 CCTGAGACCT GAGACCCT CTGCAGATAC chr16:85325254-85325334 37 5.59e-05 TGACCCCGGG GAGACCCT CCCTACACTG chr19:14586206-14586286 59 5.59e-05 TGGAGTGGCA GAGACCCC CCTCTCTGCT chr17:1531615-1531695 43 5.59e-05 GCCCGCGCCC GAGACCCT TCCCCAGAGC chr16:3068224-3068304 35 5.59e-05 AGGAGGGGCA GAGACCCT GTCCCTGACG chr19:14143122-14143202 52 5.59e-05 CCCCTTTCCT GAGACCCT CTGACTCCCT chr2:238384132-238384212 23 5.59e-05 CCAGGACCCC GAGACCCC GGACCCCGGC chr7:134379240-134379320 52 5.59e-05 TGAGGACTGA GAGACCCC AGGGGCTGGC chr7:5230248-5230328 53 5.59e-05 GCCCTCCAGG GAGACCCT CGGGTGCTGG chr11:2951697-2951777 22 5.59e-05 GAGGACCCCA GAGACCCC GGCTACTACT chr9:115096046-115096126 63 7.56e-05 CGGTCGCTGT AAGACCCC GCCTCTcggc chr17:27921268-27921348 32 7.56e-05 GGAGTGGAGA AAGACCCT CTTGGGAGGC chr10:977994-978074 46 7.56e-05 GCGCCCCTTA AAGACCCC TGCCCGCCGC chr19:1194695-1194775 58 7.56e-05 GGGTCTAGGA AAGACCCC TCTGGCTGCT chr12:30848438-30848518 44 7.56e-05 AGGGTCGCCG AAGACCCT CTCCTCACCT chr19:45752122-45752202 59 7.56e-05 GCCTACCCCC AAGACCCC CACTTTCACC chr4:128802409-128802489 49 1.31e-04 CCCAACGGCC CAGACCCC TGCTGTTTAG chr17:49244569-49244649 54 1.31e-04 CCCCGGGCCC CAGACCCC CTGCGCCTGC chr1:54872385-54872465 67 1.31e-04 GGAGGGGGCG CAGACCCC CAAGCG chr20:48330532-48330612 68 1.31e-04 CAAATGGCGA CAGACCCT CTCCC chr9:32551109-32551189 43 1.31e-04 CCCGCCGCTC CAGACCCC GGAGGAGGGC chr12:2955200-2955280 33 1.31e-04 TGCTGCCCCG CAGACCCC CATGGCCTGC chr3:53230114-53230194 36 1.31e-04 GCTGAGGCCG CAGACCCC AGGAGGGGAG chr7:87505125-87505205 18 1.31e-04 GCCGCCTGGC CAGACCCT CCCTCAGACG chr2:209119094-209119174 43 2.88e-04 GTGTGGCCTA GCGACCCC TCTGAAGGCC chr4:184020297-184020377 38 2.88e-04 CCTGGGCGCC GCGACCCT CGGCGGCCAg chr19:11200938-11201018 53 2.88e-04 TCCGCTTTGC GCGACCCC AGGGCGCCAC chr1:155053522-155053602 69 2.88e-04 GGAGGGTCTT GCGACCCC GCCT chr14:69618388-69618468 9 2.88e-04 CTGGGCCC GCGACCCC AGGGAGGAGG chr2:239335594-239335674 4 2.88e-04 GCC GCGACCCC GACGCGCCCC chr6:13710993-13711073 13 2.88e-04 ACCCTTCACC GCGACCCC CGCGCCCACC chr10:82295663-82295743 15 2.88e-04 GCTCTTCGGC GCGACCCC TGCTCctggg chr17:40610727-40610807 43 2.88e-04 GGTCTCGCCT GCGACCCC CGTGACTCCG chr1:156355485-156355565 39 2.88e-04 ACCCCCCGCC GCGACCCC CACCCAAGGG chr17:35850299-35850379 47 2.88e-04 cgccgccccc gcgACCCT GTCCCTGTGC chr6:131384430-131384510 28 2.88e-04 agcccctccc gcgacccc gccggacgag chr5:180594972-180595052 15 2.88e-04 gaagcacagt gcgacccT CCCCTTACCC chr1:1951115-1951195 20 2.88e-04 TCGGGACGCG GCGACCCC CGCGCTGGCC chr19:4267819-4267899 62 2.88e-04 GGGGCGGCCT GCGACCCC CACAGGACCA chr22:19706543-19706623 16 5.01e-04 ATGCGGCCGT GGGACCCC TCCAGGGGCC chr16:475510-475590 47 5.01e-04 GCGAGGGGCT GGGACCCC GCCGGGACGT chr1:33207191-33207271 59 5.01e-04 CCGGGCTCCC GGGACCCC CTCCTCTCGG chr7:86689107-86689187 73 5.01e-04 AGAGAGGCTG GGGACCCC chr20:30795103-30795183 58 5.01e-04 TCGGGAATGG GGGACCCT CAGGACTGCG chr18:19284242-19284322 31 5.01e-04 CCACCCGGCC GGGACCCC CAGGGGGCGG chr2:198669846-198669926 39 5.01e-04 gggggcgAAG ACGACCCC CGAGTGGGCC chr14:102983342-10298342 48 5.01e-04 AGCCGGGCGA GGGACCCC CGACCCGGGC chr16:230365-230445 56 5.01e-04 TGGAGGCCGC GGGACCCC TGGCCGGTCC chr6:158244870-158244950 31 5.01e-04 TGCCGCCTGG GGGACCCT CGCCCCCGCG chr7:157092599-157092679 55 5.01e-04 CTCCCCACGT GGGACCCT CCGCCCTGCT chr7:116503370-116503450 15 5.01e-04 TCACAAAAAG ACGACCCC CTCCCCATAG chr7:101458883-101458963 30 5.01e-04 GCGGTGCCGG GGGACCCC GGGCGCTGCC chr16:66638797-66638877 70 5.01e-04 TGAGTGCGGC GGGACCCT CGG chr19:17650077-17650157 23 5.01e-04 GGCCGCACCC GGGACCCC CAGGACCCTC chr2:47499674-47499754 61 5.01e-04 CCTGCGCACT GGGACCCC GGCCCTGGGC chr12:1772026-1772106 26 5.01e-04 TGCAAGGACG GGGACCCT GCCTTTCTTA chr11:63684044-63684124 70 5.01e-04 AGCGCTCTCC ACGACCCC CAC chr19:3358741-3358821 52 5.01e-04 GGACCCCCAG GGGACCCC CGCCCCAGGT chr17:43209414-43209494 21 5.01e-04 GGCTCGCCCC GGGACCCT CGGATGACCC chr3:99595083-99595163 39 5.01e-04 cggtgaccgc gggaccct cggccgcggc chr16:89985130-89985210 9 5.01e-04 CGGTGTGA GGGACCCC CTGGGTCCTG chr7:100184467-100184547 52 5.01e-04 CAGGGGTCTC GGGACCCC CGGGCTGGGG chr21:43298823-43298903 19 5.01e-04 TGGGGGTCCA GGGACCCC CCCGTGCGAC chr8:134581937-134582017 25 5.01e-04 AAGGCACTGA GGGACCCC CGCACTGGGC chr19:1001742-1001822 22 5.01e-04 AGGTGTCAAG GGGACCCC TGTCCCCCCA chr16:3011946-3012026 21 5.01e-04 TCAGGCCCTA GGGACCCC AGGCCGACCC chr19:45931064-45931144 48 5.77e-04 CAGCGGGGGC AGGACCCC CTAGAAGGCG chr1:1003638-1003718 53 5.77e-04 GGGGTCCTCC AGGACCCC ATGGACCCCT chr11:2913451-2913531 50 5.77e-04 CACAGCCACC AGGACCCC CACCCACCTC chr16:30933075-30933155 46 5.77e-04 CAGACGCTGG AGGACCCC GATGAGGAGG chrX:39964421-39964501 36 5.77e-04 GGGCTGGGCC GAGACCAC CCTGCGGCCC chr9:129622565-129622645 60 7.41e-04 TCGATTCCGG GAGCCCCT GAAACGCGCC chr12:111847777-11184785 48 7.41e-04 GCCAGGCCTG GAGCCCCT GGGGGCCCAC chr1:206837638-206837718 49 7.41e-04 GCGCCGCAGA AAGACCAC CGATGTGGAG chr4:1750540-1750620 42 7.41e-04 TGGGCCACCG GAGCCCCT TCTGCAGACC chr19:18169393-18169473 47 7.41e-04 GGGATTTCAG GAGCCCCC CCCCACACCT chr17:37331334-37331414 46 7.41e-04 TGTCAGGTGT GAGCCCCT CGCTCCCTCC chr6:99872724-99872804 6 7.41e-04 GTCGC GAGCCCCC GCCTCCTCCG chr1:145588636-145588716 49 7.41e-04 CTTGGCCAGG GAGCCCCC ACTCACTGTT chr19:35605662-35605742 44 7.41e-04 TTCCACTCCC AAGACCAC CAAGGGGTCG chr11:65185728-65185808 7 7.97e-04 AGTGAG AAGCCCCC TCCTGAGGGT chr11:2216344-2216424 47 7.97e-04 GGGGTCCACA AAGCCCCC TCCCTGCCCG chr1:1532718-1532798 35 7.97e-04 CTGGAACGGG AAGCCCCC CACTCCCACC chr19:39467328-39467408 33 7.97e-04 GGATTCCCTA AAGCCCCT TCCCCTAGAA chr16:90085990-90086070 45 9.52e-04 CCCTCCCCCG CCGACCCT TCCCTcgcgg chr19:954862-954942 13 9.52e-04 AACTTCACAC CCGACCCC TCCCGTGATC chr19:34286322-34286402 9 9.52e-04 GCTCCAGG CCGACCCC GAGCGCCCCC chr14:23479464-23479544 53 9.52e-04 CGCCGGACCC CCGACCCC CAACCTCGCC chr3:196756700-196756780 42 9.52e-04 TCACCTcccg ccgacccc ggaccccgcc chr2:64880477-64880557 8 9.52e-04 CGAGCTC CCGACCCC CTCCTGACCC chr15:79103977-79104057 68 9.52e-04 CCAGGCCTTT CCGACCCC GGCCG chr12:56652205-56652285 44 1.11e-03 CCCGCGCAAA CGGACCCC GGCCGCAGCG chr6:112364993-112365073 18 1.11e-03 TAGGGGCGCC CGGACCCC AGAGCAGGGC chr20:62733500-62733580 24 1.11e-03 GCAGCGGCCT CGGACCCT CCCTCCAGGG chr1:39283944-39284024 12 1.11e-03 CTGGCCCCTC CGGACCCT GGGTGGGCGG chr11:62324209-62324289 52 1.13e-03 TGCCCCAGCG CAGACCAC CTAGTCCATG chr11:69616491-69616571 38 1.13e-03 GGTGCCCTCC CAGACCAC CTGGGACCAC chr17:73852091-73852171 26 1.28e-03 GCGCCCCTCG CAGCCCCC TCTCCGGCCT chr12:48206728-48206808 24 1.28e-03 GGCCTGCGCT CAGCCCCT CGCCCGGTGG chr17:36762759-36762839 47 1.28e-03 CTCCGGGTTG CAGCCCCT CCTGCAGGCG chr19:1767516-1767596 64 1.28e-03 ACACAGCCTA CAGCCCCC GCCCTTTCC chr10:25241770-25241850 62 1.28e-03 TGGTCGCGTG CAGCCCCC GGCCCCGCCG chr11:64512683-64512763 28 1.28e-03 GCGCCCCGCC CAGCCCCC AGCTCGGGTT chr15:37393999-37394079 28 1.28e-03 TGCCGCCCAG CAGCCCCC ATGCCCCTCG chr9:101867127-101867207 66 1.28e-03 TCTGGCGGCC CAGCCCCC GGGGAGC chr8:141646112-141646192 30 1.86e-03 GGGAGGCCAC GCGCCCCC GCTTTCCCCG chr2:176944716-176944796 2 1.86e-03 g gcgccccc TGGCGGCAGC chr16:1463771-1463851 54 1.86e-03 CCAGGCAGCG GCGCCCCC TCGCGGCCGC chr1:145585483-145585563 11 1.86e-03 CGCCACTCCG GCGCCCCC TCCTGGCCGT chr3:185541042-185541122 62 1.86e-03 CCGCCTTCGG GCGCCCCC AAGGGGTCTC chr20:36849592-36849672 70 1.86e-03 CAGCTCATGT GGGACCAC AGT chr4:1580984-1581064 23 1.86e-03 cgccTGCTGG GCGCCCCC TGGTGGCCTC chr11:46141402-46141482 22 1.86e-03 CCCACTccgc gcgcccct ccccccggcg chr5:139077406-139077486 57 1.86e-03 GGAGGGGGCT GGGACCAC CCCCAGATGT chr1:26946858-26946938 4 1.86e-03 GCT GCGCCCCC GACGCCCCTC chr22:31481295-31481375 44 1.86e-03 CGGGCCTTCA GCGCCCCC TGGCGAGGCT chr14:105266680-10526676 33 1.86e-03 TCACACCCCA GCGCCCCT GCTGGCTgcg chr9:132998589-132998669 9 1.86e-03 AGCGCGGC GCGCCCCC TGGTGGTGGT chr5:79378789-79378869 20 1.86e-03 CGGGCTAACA GCGCCCCC TACAGGACGC chr20:52210676-52210756 27 1.86e-03 AAAGGCGCGG GCGCCCCC TACTCGTCCG chr10:134266806-13426688 2 1.86e-03 G GCGCCCCC TGCCGACACC chr11:63535768-63535848 66 1.86e-03 CCACCAGGTG GCGCCCCC GGCCGCC chr9:140190032-140190112 47 1.86e-03 AGCCCCGGGC GCGCCCCC TCCCCTGCCT chr20:61071648-61071728 20 1.86e-03 CAGGCGATGC GCGCCCCT GGTGGCTCGC chr12:72332629-72332709 52 2.48e-03 AGCTGATCGC ACGCCCCT TCCTCTCAAT chr4:184427150-184427230 41 2.48e-03 GTggcgggga gggccccc gcgccggggg chr6:32936690-32936770 27 2.48e-03 GCTGGGGGCT ACGCCCCC TCCCCCAGCA chr7:6677450-6677530 53 2.48e-03 GCGGCTCCGG ACGCCCCC TGGGGGGCGG chr4:183727576-183727656 38 2.48e-03 GGGTCCTGGG ACGCCCCC TCCTGCATCC chr9:77386011-77386091 55 2.48e-03 attccaccag acgcccct gcctcgccca chr7:101054689-101054769 43 2.48e-03 GCCGAGGTTC AGGACCAC CATGGGAGGG chr1:23543402-23543482 36 2.48e-03 TTggcgcccg gggcccct cggggggcgt chr19:1672161-1672241 23 2.48e-03 CCGGGCGTCG GGGCCCCC ACCCCACGGA chr19:14169951-14170031 67 2.48e-03 CCCATCTTGA ACGCCCCC CTCTTG chr1:156023737-156023817 42 2.48e-03 CGCCAGGCGG GGGCCCCT GGGGGGCCTC chr17:27071433-27071513 7 2.69e-03 CGAGGG AGGCCCCC CCCGCAGGAA chr19:49399626-49399706 16 2.69e-03 AGACTCCCAC AGGCCCCT CCCCTCCAGG chr2:30370794-30370874 40 2.69e-03 GCTGCCGGGT GAGCCCAC CCGGGGGTCG chrX:1573182-1573262 30 2.69e-03 TCCCTAAACG GAGCCCAC CTCCAGGGCA chr1:84543557-84543637 10 2.69e-03 CGCCACCTC AGGCCCCC GCCCCAGGCT chr16:28502795-28502875 11 2.71e-03 CACTCACCAG AAGCCCAC CGCGTTCTTC chr19:12949124-12949204 23 3.26e-03 CGGGGGCTGG CCGCCCCT TCTCCCGCCG -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GVGMCCCC MEME-1 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr1:19734335-19734415 5.6e-05 16_[+1]_56 chr10:75757476-75757556 5.6e-05 24_[+1]_48 chrX:153637746-153637826 5.6e-05 53_[+1]_19 chr19:7990124-7990204 5.6e-05 10_[+1]_62 chr22:39915990-39916070 5.6e-05 52_[+1]_20 chr2:25599736-25599816 5.6e-05 52_[+1]_20 chr19:1267156-1267236 5.6e-05 50_[+1]_22 chr1:153957945-153958025 5.6e-05 26_[+1]_46 chr19:56904552-56904632 5.6e-05 17_[+1]_55 chr11:65083122-65083202 5.6e-05 33_[+1]_39 chr5:133332512-133332592 5.6e-05 55_[+1]_17 chr13:27746262-27746342 5.6e-05 39_[+1]_33 chr4:141174431-141174511 5.6e-05 14_[+1]_58 chr17:40115174-40115254 5.6e-05 52_[+1]_20 chr16:85325254-85325334 5.6e-05 36_[+1]_36 chr19:14586206-14586286 5.6e-05 58_[+1]_14 chr17:1531615-1531695 5.6e-05 42_[+1]_30 chr16:3068224-3068304 5.6e-05 34_[+1]_38 chr19:14143122-14143202 5.6e-05 51_[+1]_21 chr2:238384132-238384212 5.6e-05 22_[+1]_50 chr7:134379240-134379320 5.6e-05 51_[+1]_21 chr7:5230248-5230328 5.6e-05 52_[+1]_20 chr11:2951697-2951777 5.6e-05 21_[+1]_51 chr9:115096046-115096126 7.6e-05 62_[+1]_10 chr17:27921268-27921348 7.6e-05 31_[+1]_41 chr10:977994-978074 7.6e-05 45_[+1]_27 chr19:1194695-1194775 7.6e-05 57_[+1]_15 chr12:30848438-30848518 7.6e-05 43_[+1]_29 chr19:45752122-45752202 7.6e-05 58_[+1]_14 chr4:128802409-128802489 0.00013 48_[+1]_24 chr17:49244569-49244649 0.00013 53_[+1]_19 chr1:54872385-54872465 0.00013 66_[+1]_6 chr20:48330532-48330612 0.00013 67_[+1]_5 chr9:32551109-32551189 0.00013 42_[+1]_30 chr12:2955200-2955280 0.00013 32_[+1]_40 chr3:53230114-53230194 0.00013 35_[+1]_37 chr7:87505125-87505205 0.00013 17_[+1]_55 chr2:209119094-209119174 0.00029 42_[+1]_30 chr4:184020297-184020377 0.00029 37_[+1]_35 chr19:11200938-11201018 0.00029 52_[+1]_20 chr1:155053522-155053602 0.00029 68_[+1]_4 chr14:69618388-69618468 0.00029 8_[+1]_64 chr2:239335594-239335674 0.00029 3_[+1]_69 chr6:13710993-13711073 0.00029 12_[+1]_60 chr10:82295663-82295743 0.00029 14_[+1]_58 chr17:40610727-40610807 0.00029 42_[+1]_30 chr1:156355485-156355565 0.00029 38_[+1]_34 chr17:35850299-35850379 0.00029 46_[+1]_26 chr6:131384430-131384510 0.00029 27_[+1]_45 chr5:180594972-180595052 0.00029 14_[+1]_58 chr1:1951115-1951195 0.00029 19_[+1]_53 chr19:4267819-4267899 0.00029 61_[+1]_11 chr22:19706543-19706623 0.0005 15_[+1]_57 chr16:475510-475590 0.0005 46_[+1]_26 chr1:33207191-33207271 0.0005 58_[+1]_14 chr7:86689107-86689187 0.0005 72_[+1] chr20:30795103-30795183 0.0005 57_[+1]_15 chr18:19284242-19284322 0.0005 30_[+1]_42 chr2:198669846-198669926 0.0005 38_[+1]_34 chr14:102983342-10298342 0.0005 47_[+1]_25 chr16:230365-230445 0.0005 55_[+1]_17 chr6:158244870-158244950 0.0005 30_[+1]_42 chr7:157092599-157092679 0.0005 54_[+1]_18 chr7:116503370-116503450 0.0005 14_[+1]_58 chr7:101458883-101458963 0.0005 29_[+1]_43 chr16:66638797-66638877 0.0005 69_[+1]_3 chr19:17650077-17650157 0.0005 22_[+1]_50 chr2:47499674-47499754 0.0005 60_[+1]_12 chr12:1772026-1772106 0.0005 25_[+1]_47 chr11:63684044-63684124 0.0005 69_[+1]_3 chr19:3358741-3358821 0.0005 51_[+1]_21 chr17:43209414-43209494 0.0005 20_[+1]_52 chr3:99595083-99595163 0.0005 38_[+1]_34 chr16:89985130-89985210 0.0005 8_[+1]_64 chr7:100184467-100184547 0.0005 51_[+1]_21 chr21:43298823-43298903 0.0005 18_[+1]_54 chr8:134581937-134582017 0.0005 24_[+1]_48 chr19:1001742-1001822 0.0005 21_[+1]_51 chr16:3011946-3012026 0.0005 20_[+1]_52 chr19:45931064-45931144 0.00058 47_[+1]_25 chr1:1003638-1003718 0.00058 52_[+1]_20 chr11:2913451-2913531 0.00058 49_[+1]_23 chr16:30933075-30933155 0.00058 45_[+1]_27 chrX:39964421-39964501 0.00058 35_[+1]_37 chr9:129622565-129622645 0.00074 59_[+1]_13 chr12:111847777-11184785 0.00074 47_[+1]_25 chr1:206837638-206837718 0.00074 48_[+1]_24 chr4:1750540-1750620 0.00074 41_[+1]_31 chr19:18169393-18169473 0.00074 46_[+1]_26 chr17:37331334-37331414 0.00074 45_[+1]_27 chr6:99872724-99872804 0.00074 5_[+1]_67 chr1:145588636-145588716 0.00074 48_[+1]_24 chr19:35605662-35605742 0.00074 43_[+1]_29 chr11:65185728-65185808 0.0008 6_[+1]_66 chr11:2216344-2216424 0.0008 46_[+1]_26 chr1:1532718-1532798 0.0008 34_[+1]_38 chr19:39467328-39467408 0.0008 32_[+1]_40 chr16:90085990-90086070 0.00095 44_[+1]_28 chr19:954862-954942 0.00095 12_[+1]_60 chr19:34286322-34286402 0.00095 8_[+1]_64 chr14:23479464-23479544 0.00095 52_[+1]_20 chr3:196756700-196756780 0.00095 41_[+1]_31 chr2:64880477-64880557 0.00095 7_[+1]_65 chr15:79103977-79104057 0.00095 67_[+1]_5 chr12:56652205-56652285 0.0011 43_[+1]_29 chr6:112364993-112365073 0.0011 17_[+1]_55 chr20:62733500-62733580 0.0011 23_[+1]_49 chr1:39283944-39284024 0.0011 11_[+1]_61 chr11:62324209-62324289 0.0011 51_[+1]_21 chr11:69616491-69616571 0.0011 37_[+1]_35 chr17:73852091-73852171 0.0013 25_[+1]_47 chr12:48206728-48206808 0.0013 23_[+1]_49 chr17:36762759-36762839 0.0013 46_[+1]_26 chr19:1767516-1767596 0.0013 63_[+1]_9 chr10:25241770-25241850 0.0013 61_[+1]_11 chr11:64512683-64512763 0.0013 27_[+1]_45 chr15:37393999-37394079 0.0013 27_[+1]_45 chr9:101867127-101867207 0.0013 65_[+1]_7 chr8:141646112-141646192 0.0019 29_[+1]_43 chr2:176944716-176944796 0.0019 1_[+1]_71 chr16:1463771-1463851 0.0019 53_[+1]_19 chr1:145585483-145585563 0.0019 10_[+1]_62 chr3:185541042-185541122 0.0019 61_[+1]_11 chr20:36849592-36849672 0.0019 69_[+1]_3 chr4:1580984-1581064 0.0019 22_[+1]_50 chr11:46141402-46141482 0.0019 21_[+1]_51 chr5:139077406-139077486 0.0019 56_[+1]_16 chr1:26946858-26946938 0.0019 3_[+1]_69 chr22:31481295-31481375 0.0019 43_[+1]_29 chr14:105266680-10526676 0.0019 32_[+1]_40 chr9:132998589-132998669 0.0019 8_[+1]_64 chr5:79378789-79378869 0.0019 19_[+1]_53 chr20:52210676-52210756 0.0019 26_[+1]_46 chr10:134266806-13426688 0.0019 1_[+1]_71 chr11:63535768-63535848 0.0019 65_[+1]_7 chr9:140190032-140190112 0.0019 46_[+1]_26 chr20:61071648-61071728 0.0019 19_[+1]_53 chr12:72332629-72332709 0.0025 51_[+1]_21 chr4:184427150-184427230 0.0025 40_[+1]_32 chr6:32936690-32936770 0.0025 26_[+1]_46 chr7:6677450-6677530 0.0025 52_[+1]_20 chr4:183727576-183727656 0.0025 37_[+1]_35 chr9:77386011-77386091 0.0025 54_[+1]_18 chr7:101054689-101054769 0.0025 42_[+1]_30 chr1:23543402-23543482 0.0025 35_[+1]_37 chr19:1672161-1672241 0.0025 22_[+1]_50 chr19:14169951-14170031 0.0025 66_[+1]_6 chr1:156023737-156023817 0.0025 41_[+1]_31 chr17:27071433-27071513 0.0027 6_[+1]_66 chr19:49399626-49399706 0.0027 15_[+1]_57 chr2:30370794-30370874 0.0027 39_[+1]_33 chrX:1573182-1573262 0.0027 29_[+1]_43 chr1:84543557-84543637 0.0027 9_[+1]_63 chr16:28502795-28502875 0.0027 10_[+1]_62 chr19:12949124-12949204 0.0033 22_[+1]_50 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GVGMCCCC MEME-1 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF GVGMCCCC width=8 seqs=155 chr1:19734335-19734415 ( 17) GAGACCCT 1 chr10:75757476-75757556 ( 25) GAGACCCC 1 chrX:153637746-153637826 ( 54) GAGACCCC 1 chr19:7990124-7990204 ( 11) GAGACCCC 1 chr22:39915990-39916070 ( 53) GAGACCCC 1 chr2:25599736-25599816 ( 53) GAGACCCT 1 chr19:1267156-1267236 ( 51) GAGACCCC 1 chr1:153957945-153958025 ( 27) GAGACCCC 1 chr19:56904552-56904632 ( 18) GAGACCCC 1 chr11:65083122-65083202 ( 34) GAGACCCC 1 chr5:133332512-133332592 ( 56) GAGACCCT 1 chr13:27746262-27746342 ( 40) GAGACCCC 1 chr4:141174431-141174511 ( 15) GAGACCCC 1 chr17:40115174-40115254 ( 53) GAGACCCT 1 chr16:85325254-85325334 ( 37) GAGACCCT 1 chr19:14586206-14586286 ( 59) GAGACCCC 1 chr17:1531615-1531695 ( 43) GAGACCCT 1 chr16:3068224-3068304 ( 35) GAGACCCT 1 chr19:14143122-14143202 ( 52) GAGACCCT 1 chr2:238384132-238384212 ( 23) GAGACCCC 1 chr7:134379240-134379320 ( 52) GAGACCCC 1 chr7:5230248-5230328 ( 53) GAGACCCT 1 chr11:2951697-2951777 ( 22) GAGACCCC 1 chr9:115096046-115096126 ( 63) AAGACCCC 1 chr17:27921268-27921348 ( 32) AAGACCCT 1 chr10:977994-978074 ( 46) AAGACCCC 1 chr19:1194695-1194775 ( 58) AAGACCCC 1 chr12:30848438-30848518 ( 44) AAGACCCT 1 chr19:45752122-45752202 ( 59) AAGACCCC 1 chr4:128802409-128802489 ( 49) CAGACCCC 1 chr17:49244569-49244649 ( 54) CAGACCCC 1 chr1:54872385-54872465 ( 67) CAGACCCC 1 chr20:48330532-48330612 ( 68) CAGACCCT 1 chr9:32551109-32551189 ( 43) CAGACCCC 1 chr12:2955200-2955280 ( 33) CAGACCCC 1 chr3:53230114-53230194 ( 36) CAGACCCC 1 chr7:87505125-87505205 ( 18) CAGACCCT 1 chr2:209119094-209119174 ( 43) GCGACCCC 1 chr4:184020297-184020377 ( 38) GCGACCCT 1 chr19:11200938-11201018 ( 53) GCGACCCC 1 chr1:155053522-155053602 ( 69) GCGACCCC 1 chr14:69618388-69618468 ( 9) GCGACCCC 1 chr2:239335594-239335674 ( 4) GCGACCCC 1 chr6:13710993-13711073 ( 13) GCGACCCC 1 chr10:82295663-82295743 ( 15) GCGACCCC 1 chr17:40610727-40610807 ( 43) GCGACCCC 1 chr1:156355485-156355565 ( 39) GCGACCCC 1 chr17:35850299-35850379 ( 47) GCGACCCT 1 chr6:131384430-131384510 ( 28) GCGACCCC 1 chr5:180594972-180595052 ( 15) GCGACCCT 1 chr1:1951115-1951195 ( 20) GCGACCCC 1 chr19:4267819-4267899 ( 62) GCGACCCC 1 chr22:19706543-19706623 ( 16) GGGACCCC 1 chr16:475510-475590 ( 47) GGGACCCC 1 chr1:33207191-33207271 ( 59) GGGACCCC 1 chr7:86689107-86689187 ( 73) GGGACCCC 1 chr20:30795103-30795183 ( 58) GGGACCCT 1 chr18:19284242-19284322 ( 31) GGGACCCC 1 chr2:198669846-198669926 ( 39) ACGACCCC 1 chr14:102983342-10298342 ( 48) GGGACCCC 1 chr16:230365-230445 ( 56) GGGACCCC 1 chr6:158244870-158244950 ( 31) GGGACCCT 1 chr7:157092599-157092679 ( 55) GGGACCCT 1 chr7:116503370-116503450 ( 15) ACGACCCC 1 chr7:101458883-101458963 ( 30) GGGACCCC 1 chr16:66638797-66638877 ( 70) GGGACCCT 1 chr19:17650077-17650157 ( 23) GGGACCCC 1 chr2:47499674-47499754 ( 61) GGGACCCC 1 chr12:1772026-1772106 ( 26) GGGACCCT 1 chr11:63684044-63684124 ( 70) ACGACCCC 1 chr19:3358741-3358821 ( 52) GGGACCCC 1 chr17:43209414-43209494 ( 21) GGGACCCT 1 chr3:99595083-99595163 ( 39) GGGACCCT 1 chr16:89985130-89985210 ( 9) GGGACCCC 1 chr7:100184467-100184547 ( 52) GGGACCCC 1 chr21:43298823-43298903 ( 19) GGGACCCC 1 chr8:134581937-134582017 ( 25) GGGACCCC 1 chr19:1001742-1001822 ( 22) GGGACCCC 1 chr16:3011946-3012026 ( 21) GGGACCCC 1 chr19:45931064-45931144 ( 48) AGGACCCC 1 chr1:1003638-1003718 ( 53) AGGACCCC 1 chr11:2913451-2913531 ( 50) AGGACCCC 1 chr16:30933075-30933155 ( 46) AGGACCCC 1 chrX:39964421-39964501 ( 36) GAGACCAC 1 chr9:129622565-129622645 ( 60) GAGCCCCT 1 chr12:111847777-11184785 ( 48) GAGCCCCT 1 chr1:206837638-206837718 ( 49) AAGACCAC 1 chr4:1750540-1750620 ( 42) GAGCCCCT 1 chr19:18169393-18169473 ( 47) GAGCCCCC 1 chr17:37331334-37331414 ( 46) GAGCCCCT 1 chr6:99872724-99872804 ( 6) GAGCCCCC 1 chr1:145588636-145588716 ( 49) GAGCCCCC 1 chr19:35605662-35605742 ( 44) AAGACCAC 1 chr11:65185728-65185808 ( 7) AAGCCCCC 1 chr11:2216344-2216424 ( 47) AAGCCCCC 1 chr1:1532718-1532798 ( 35) AAGCCCCC 1 chr19:39467328-39467408 ( 33) AAGCCCCT 1 chr16:90085990-90086070 ( 45) CCGACCCT 1 chr19:954862-954942 ( 13) CCGACCCC 1 chr19:34286322-34286402 ( 9) CCGACCCC 1 chr14:23479464-23479544 ( 53) CCGACCCC 1 chr3:196756700-196756780 ( 42) CCGACCCC 1 chr2:64880477-64880557 ( 8) CCGACCCC 1 chr15:79103977-79104057 ( 68) CCGACCCC 1 chr12:56652205-56652285 ( 44) CGGACCCC 1 chr6:112364993-112365073 ( 18) CGGACCCC 1 chr20:62733500-62733580 ( 24) CGGACCCT 1 chr1:39283944-39284024 ( 12) CGGACCCT 1 chr11:62324209-62324289 ( 52) CAGACCAC 1 chr11:69616491-69616571 ( 38) CAGACCAC 1 chr17:73852091-73852171 ( 26) CAGCCCCC 1 chr12:48206728-48206808 ( 24) CAGCCCCT 1 chr17:36762759-36762839 ( 47) CAGCCCCT 1 chr19:1767516-1767596 ( 64) CAGCCCCC 1 chr10:25241770-25241850 ( 62) CAGCCCCC 1 chr11:64512683-64512763 ( 28) CAGCCCCC 1 chr15:37393999-37394079 ( 28) CAGCCCCC 1 chr9:101867127-101867207 ( 66) CAGCCCCC 1 chr8:141646112-141646192 ( 30) GCGCCCCC 1 chr2:176944716-176944796 ( 2) GCGCCCCC 1 chr16:1463771-1463851 ( 54) GCGCCCCC 1 chr1:145585483-145585563 ( 11) GCGCCCCC 1 chr3:185541042-185541122 ( 62) GCGCCCCC 1 chr20:36849592-36849672 ( 70) GGGACCAC 1 chr4:1580984-1581064 ( 23) GCGCCCCC 1 chr11:46141402-46141482 ( 22) GCGCCCCT 1 chr5:139077406-139077486 ( 57) GGGACCAC 1 chr1:26946858-26946938 ( 4) GCGCCCCC 1 chr22:31481295-31481375 ( 44) GCGCCCCC 1 chr14:105266680-10526676 ( 33) GCGCCCCT 1 chr9:132998589-132998669 ( 9) GCGCCCCC 1 chr5:79378789-79378869 ( 20) GCGCCCCC 1 chr20:52210676-52210756 ( 27) GCGCCCCC 1 chr10:134266806-13426688 ( 2) GCGCCCCC 1 chr11:63535768-63535848 ( 66) GCGCCCCC 1 chr9:140190032-140190112 ( 47) GCGCCCCC 1 chr20:61071648-61071728 ( 20) GCGCCCCT 1 chr12:72332629-72332709 ( 52) ACGCCCCT 1 chr4:184427150-184427230 ( 41) GGGCCCCC 1 chr6:32936690-32936770 ( 27) ACGCCCCC 1 chr7:6677450-6677530 ( 53) ACGCCCCC 1 chr4:183727576-183727656 ( 38) ACGCCCCC 1 chr9:77386011-77386091 ( 55) ACGCCCCT 1 chr7:101054689-101054769 ( 43) AGGACCAC 1 chr1:23543402-23543482 ( 36) GGGCCCCT 1 chr19:1672161-1672241 ( 23) GGGCCCCC 1 chr19:14169951-14170031 ( 67) ACGCCCCC 1 chr1:156023737-156023817 ( 42) GGGCCCCT 1 chr17:27071433-27071513 ( 7) AGGCCCCC 1 chr19:49399626-49399706 ( 16) AGGCCCCT 1 chr2:30370794-30370874 ( 40) GAGCCCAC 1 chrX:1573182-1573262 ( 30) GAGCCCAC 1 chr1:84543557-84543637 ( 10) AGGCCCCC 1 chr16:28502795-28502875 ( 11) AAGCCCAC 1 chr19:12949124-12949204 ( 23) CCGCCCCT 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GVGMCCCC MEME-1 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 7.78803 E= 2.1e-031 57 -92 74 -1392 166 -21 -44 -1392 -1392 -1392 144 -1392 234 -10 -1392 -1392 -1392 145 -1392 -1392 -1392 145 -1392 -1392 -88 135 -1392 -1392 -1392 100 -1392 99 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GVGMCCCC MEME-1 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 155 E= 2.1e-031 0.193548 0.193548 0.612903 0.000000 0.412903 0.316129 0.270968 0.000000 0.000000 0.000000 1.000000 0.000000 0.658065 0.341935 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.070968 0.929032 0.000000 0.000000 0.000000 0.729032 0.000000 0.270968 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GVGMCCCC MEME-1 regular expression -------------------------------------------------------------------------------- G[ACG]G[AC]CCC[CT] -------------------------------------------------------------------------------- Time 5.65 secs. ******************************************************************************** ******************************************************************************** MOTIF RGGGGKCB MEME-2 width = 8 sites = 155 llr = 957 E-value = 1.3e-030 ******************************************************************************** -------------------------------------------------------------------------------- Motif RGGGGKCB MEME-2 Description -------------------------------------------------------------------------------- Simplified A 33:::::: pos.-specific C ::::::a2 probability G 57aaa4:4 matrix T 2::::6:4 bits 2.9 2.6 2.4 2.1 Relative 1.8 Entropy 1.5 **** (8.9 bits) 1.2 ***** 0.9 ****** 0.6 ******* 0.3 ******** 0.0 -------- Multilevel GGGGGTCG consensus AA G T sequence C -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif RGGGGKCB MEME-2 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr22:19706543-19706623 36 5.77e-06 CAGGGGCCCC AAGGGTCT gcgggggctg chr19:46142543-46142623 61 5.77e-06 TGGTCTGCGA AAGGGTCT CACCCAGCTC chr3:185541042-185541122 71 2.21e-05 GGCGCCCCCA AGGGGTCT CC chr11:62324209-62324289 33 2.21e-05 AGGCTGAGGT AGGGGTCT CTGCCCCAGC chr19:49399626-49399706 45 2.21e-05 GAACGCCCCC AGGGGTCT TTGGTCACCT chr19:1194695-1194775 46 2.21e-05 GATACCTGGC AGGGGTCT AGGAAAGACC chr10:73468128-73468208 60 2.21e-05 CTGGCAGGGG AGGGGTCT CCACGCTGTT chr17:8649341-8649421 32 2.21e-05 GTGGTGGGCT AGGGGTCT CGGGCGGGGG chr7:100184467-100184547 43 2.21e-05 AGCCTCTGGC AGGGGTCT CGGGACCCCC chr17:38242884-38242964 35 2.21e-05 AGAGGCTGAA AGGGGTCT GCGGCCCCAG chr1:52195682-52195762 5 3.84e-05 CCCC GAGGGTCT GGGAGAGGGG chr19:1767516-1767596 13 3.84e-05 TCCGGAACTT GAGGGTCT CCCCCCAGTC chr1:206837638-206837718 6 3.84e-05 GCCCT GAGGGTCT CTCACCCTTA chr1:155053522-155053602 60 3.84e-05 GTCACGTGGG GAGGGTCT TGCGACCCCG chr22:19953738-19953818 46 3.84e-05 TGGCTCTTGT GAGGGTCT AGCCATCCCC chr1:15757715-15757795 30 3.84e-05 gagggtgggC GAGGGTCT GGGGTCTTCC chr3:13696967-13697047 59 3.84e-05 CGCGAGGCCT GAGGGTCT CCCAGGCGCG chr20:61071648-61071728 66 3.84e-05 CTGGGTCTGC GAGGGTCT CCAGGAG chr15:78423878-78423958 32 9.08e-05 GGGGGCGCGC GGGGGTCT CGGAGGCGGG chr11:47421643-47421723 33 9.08e-05 GGTAGCAGGA GGGGGTCT CCAGGGTGCG chr5:76787760-76787840 8 9.08e-05 CGGGGCC GGGGGTCT GCAGCTCCAG chr2:61922178-61922258 72 9.08e-05 TGTGTGGGTA GGGGGTCT T chr17:47074616-47074696 58 9.08e-05 CTGTGGCGTC GGGGGTCT TTCCCTGCAG chr19:822111-822191 41 9.08e-05 CGGGGGTCTC GGGGGTCT CAGGTCTGCG chrX:131119625-131119705 20 1.08e-04 TTCAGGCTGC TGGGGTCT CCAACCTTGA chr16:85286971-85287051 54 1.08e-04 GGAAATGGGG TGGGGTCT CCAGGGGGAA chr9:101867127-101867207 51 1.08e-04 GGGCCGGGGC TGGGGTCT GGCGGCCCAG chr1:33338330-33338410 34 1.08e-04 AGGGTCCTGG TGGGGTCT TGGCCTCCAG chr9:19230269-19230349 27 1.67e-04 GGGGTCGCAC AGGGGTCG GGCGGGGGAG chr20:30795103-30795183 43 1.67e-04 CAGGGAGCCT AGGGGTCG GGAATGGGGG chr5:172199060-172199140 3 1.67e-04 TG AGGGGTCG CAAGGCCCCG chr19:35605662-35605742 54 1.67e-04 AAGACCACCA AGGGGTCG TCCCAGACAC chr22:38198362-38198442 20 2.27e-04 gacggctgcc gagggtcg cgggcagggg chr10:97804021-97804101 39 2.27e-04 AGGGGGCGCA GAGGGTCG CGGGGGAGCC chr12:30848438-30848518 33 2.27e-04 TTCGGCGGAA GAGGGTCG CCGAAGACCC chr19:45287798-45287878 47 2.27e-04 gggcgcctct gagggtcg cacaaagtgg chr11:335842-335922 38 2.58e-04 GGGAGGGAGG AAGGGGCT TTGCAGGGGA chr14:75762885-75762965 18 2.58e-04 TGATTTGAGG AAGGGGCT GGGATCCTTC chr19:917844-917924 20 4.26e-04 TGTCCCCTGC AGGGGTCC CCCCCAACCT chr9:129622565-129622645 16 4.26e-04 CCAGTGCTGG GGGGGTCG AGGGTCCTGG chr19:3307484-3307564 28 4.26e-04 CTTCAGCACC GGGGGTCG CGGACAGCTC chr5:71616462-71616542 37 4.26e-04 GGTGACCACT GGGGGTCG TGGATACCCC chr12:122241354-12224143 42 4.26e-04 GCTCCGGGGA GGGGGTCG CGGGCCGCAG chr7:148396941-148397021 51 4.26e-04 CCCCAGACTC GGGGGTCG TCGCTTTTTT chr19:1267156-1267236 34 4.26e-04 GGGTGGATGA AGGGGTCC CAGCCGCCTG chr19:11200938-11201018 32 4.26e-04 CCGCGGGCTC AGGGGTCC CGATCCGCTT chr4:183727576-183727656 26 4.26e-04 CCCCGTGGGC AGGGGTCC TGGGACGCCC chr6:158244870-158244950 57 4.26e-04 CGGGGCGGGT GGGGGTCG AGACCTCGGC chr19:56904552-56904632 40 4.26e-04 CACCCACCTA AGGGGTCC ATGCACCTGG chr17:27071433-27071513 29 4.26e-04 CAGGAATCCG AGGGGTCC GGGCGGGTCC chr7:116503370-116503450 68 4.26e-04 GCCCCCCCCC GGGGGTCG ATTTG chr9:139566242-139566322 60 4.26e-04 AGCCCTTCCC AGGGGTCC TCCCTAGACC chr8:143751085-143751165 24 4.26e-04 CTCAGGCCGC GGGGGTCG CGCGGGAAGC chr17:55055275-55055355 49 4.26e-04 GCGCATTTGC AGGGGTCC TGGTGGGCTT chr19:13274008-13274088 34 4.26e-04 AGGCGGAGGC GGGGGTCG CGCCCAGGTC chr2:30370794-30370874 50 4.26e-04 GAGCCCACCC GGGGGTCG CCCGGGCCGG chr16:30933075-30933155 67 4.26e-04 GAGGAGGGGC GGGGGTCG GTTCAA chr7:98476151-98476231 55 4.26e-04 GGGCTCGGCT GGGGGTCG CCGGGGTCGC chr10:3088091-3088171 24 4.26e-04 CAGACGCTGG AGGGGTCC CGGGGGTCAG chr10:134266806-13426688 61 4.26e-04 gcggggcccg gggggTCG TTCCGGAGTG chr6:43726401-43726481 61 4.26e-04 GGTACCTGGG AGGGGTCC TGACTGAGGA chr17:46599577-46599657 34 5.16e-04 TGGGGAGTGG AGGGGGCT GCAAGCCATT chr17:40826271-40826351 62 5.16e-04 GGGAACATGC TGGGGTCG CCAGACTATG chr19:506913-506993 41 5.16e-04 GGAGCTGGGG AGGGGGCT TCTCCCACGA chr11:64948448-64948528 9 5.16e-04 GTGGGGAG AGGGGGCT GCCGTCCTGC chr5:139077406-139077486 49 5.16e-04 CACCTCTAGG AGGGGGCT GGGACCACCC chr7:23511029-23511109 39 5.16e-04 GGCTAGGGGC TGGGGTCG TCGGGGGCCT chr2:106020410-106020490 43 5.16e-04 CACCCTGTGG TGGGGTCG TGGGGGGGAG chr19:1401578-1401658 73 5.16e-04 GTGGCGGGAG TGGGGTCG chr19:39226706-39226786 14 5.16e-04 TAGGCAGGGA TGGGGTCG GATTTGGGTG chr2:139191906-139191986 27 5.16e-04 TGTGGTGGGG AGGGGGCT GGTGGTCCTT chr4:128802409-128802489 33 5.60e-04 GGTGCTTAGG GAGGGTCC CAACGGCCCA chr19:14542902-14542982 50 5.60e-04 CCGAAGGAGT GAGGGTCC GACGGCGGCC chr11:65185728-65185808 19 5.60e-04 GCCCCCTCCT GAGGGTCC TCCCCTGCCT chr19:17403187-17403267 37 5.60e-04 CATCTTCCGT GAGGGTCC CGGCTGCGGC chr9:130705245-130705325 40 5.60e-04 GGTGGGCCAG GAGGGTCC CAGCATGGAT chrX:153637746-153637826 35 6.20e-04 CTGGGGCAAG GAGGGGCT GGTGCCTGAG chr16:475510-475590 39 6.20e-04 GCAAGCCGGC GAGGGGCT GGGACCCCGC chr6:32936690-32936770 12 6.20e-04 TTCGGGAAGG GAGGGGCT GGGGGCTACG chr7:6677450-6677530 7 6.20e-04 ATCCAG GAGGGGCT GTCATCGTCT chr1:11796623-11796703 14 6.20e-04 AGGTGCGCGG GAGGGGCT TGTAGGCGGC chr22:30821674-30821754 16 6.20e-04 GAGCCTGGGA GAGGGGCT TCGGTGCGCG chr11:63684044-63684124 23 6.20e-04 TCAGCGTGGC TAGGGTCC GGCGGGGTGG chr19:14169951-14170031 49 6.20e-04 CAGGGGCTTC GAGGGGCT CCCATCTTGA chr20:36849592-36849672 20 7.59e-04 GGGGACAGCC TAGGGGCT GCAGGGACCC chr10:76868586-76868666 37 7.59e-04 CAGCACCCCC GGGGGTCC TGGAGAAGGT chr1:1003638-1003718 42 7.59e-04 GTGTGTGTGG GGGGGTCC TCCAGGACCC chr19:11314648-11314728 66 7.59e-04 CAGTCATCAC GGGGGTCC CAGAGGC chr2:20442148-20442228 63 7.59e-04 CGGACGGGGC GGGGGTCC CCCTTGGTGT chr2:64880477-64880557 62 7.59e-04 CGCAGGCGCC GGGGGTCC GAGAGCGCGG chr5:79378789-79378869 51 7.59e-04 AGCCGCGGGC GGGGGTCC GGGGTCCGGG chr1:84543557-84543637 37 7.59e-04 TCTGCCAGCT GGGGGTCC ACCGCCCGCC chr11:2216344-2216424 36 7.59e-04 GAAAGAGGCT GGGGGTCC ACAAAGCCCC chr20:52210676-52210756 66 7.59e-04 TGCAGGCGCG GGGGGTCC CTAGAGC chr21:43298823-43298903 10 7.59e-04 CGCGGGGTT GGGGGTCC AGGGACCCCC chr7:134379240-134379320 35 7.59e-04 GAATTGGGCC TAGGGGCT GAGGACTGAG chr11:63688711-63688791 71 7.59e-04 CATGGACCAA GGGGGTCC CA chr17:71228778-71228858 21 9.29e-04 GCAGGGGCCT GGGGGGCT TCCCTGGGGG chr10:81205490-81205570 44 9.29e-04 GCTCCGGGGG TGGGGTCC ACGATGCCCC chr1:54872385-54872465 22 9.29e-04 GTGGACCACT GGGGGGCT AGGGGGGCGC chr12:56320876-56320956 53 9.29e-04 GTGAGCGGGC TGGGGTCC CGCCCCCCTC chr4:6722096-6722176 22 9.29e-04 CTGTGGGGTG TGGGGTCC GCGGTGGCTG chr22:38852088-38852168 3 9.29e-04 gc ggggggcT GCTGGCCCCG chr3:128216824-128216904 58 9.29e-04 GGGTCTCGGG TGGGGTCC GCGGAGCCGG chr11:63535768-63535848 17 9.29e-04 GGAGCTGGGC GGGGGGCT CCCCCGCCAG chr7:100492622-100492702 37 9.76e-04 GGAGGGGGCC TGGGGGCT CGAGGGCCTT chr9:132998589-132998669 43 9.76e-04 CCAACGCACC TGGGGGCT GCAACCCCAC chrX:39964421-39964501 23 9.76e-04 CCCCTCCCCG TGGGGGCT GGGCCGAGAC chr11:64512683-64512763 13 1.02e-03 TGCGGTGGGG AAGGGGCG CCCCGCCCAG chr1:156023737-156023817 70 1.02e-03 TGGGAGGGGG AAGGGGCG TGC chr19:7990124-7990204 34 1.14e-03 AGGGCCGGCT AGGGGGCG CCGCGCCCCT chr2:176944716-176944796 49 1.14e-03 CGGAGGGCTC AGGGGGCG CACAGGGGAC chr18:19284242-19284322 40 1.14e-03 CGGGACCCCC AGGGGGCG GGCGAACGGG chr1:919692-919772 64 1.14e-03 TGCCCTGGTC AGGGGGCG CCAGGTCCT chr19:18526032-18526112 41 1.14e-03 GAGGGGTTGC AGGGGGCG CCAGCCCCAG chr4:1750540-1750620 20 1.14e-03 AACAGCCTGC AGGGGGCG CCATTGGGCC chr19:34286322-34286402 48 1.14e-03 TGCGGCCGCT AGGGGGCG TCCAGGCCCG chr20:62733500-62733580 38 1.14e-03 CCCTCCCTCC AGGGGGCG CTGTGGGCTC chr12:2955200-2955280 58 1.14e-03 TGCTGGAGCT AGGGGGCG CCAGAAGCCT chr4:184427150-184427230 20 1.31e-03 GAGAGGAAGA GAGGGGCG TGTGTggcgg chr10:75757476-75757556 55 1.31e-03 TGATTCTGCA GAGGGGCG GAGCCCCCCA chr11:46141402-46141482 55 1.31e-03 gcgggcgggg gaggggcg gccgcggccc chr11:65083122-65083202 23 1.31e-03 GAGCCCGGGG GAGGGGCG CTGGAGACCC chr7:101054689-101054769 56 1.31e-03 ACCACCATGG GAGGGGCG TCAGGACACG chr2:239335594-239335674 72 1.31e-03 CTTCCTGCCC GAGGGGCG T chr7:5230248-5230328 36 1.31e-03 GGCGTGCAGG GAGGGGCG CCCTCCAGGG chr19:4067608-4067688 15 1.35e-03 CCCGCTGCGC TAGGGGCG TCAGCGGGGG chr6:112364993-112365073 8 1.35e-03 TTTTATA TAGGGGCG CCCGGACCCC chr12:48206728-48206808 5 1.82e-03 ATCT GGGGGGCG AGGCCTGCGC chr8:141646112-141646192 60 1.82e-03 GCCCCCCGGT GGGGGGCG CAGAACCCTC chr1:150521703-150521783 1 1.82e-03 . ggggggcg cccggcgcgc chr13:77904013-77904093 39 1.82e-03 GGCTGCAGCC GGGGGGCG TGGGGGCCGC chr16:57126886-57126966 67 1.82e-03 TCCCTGGGGA GGGGGGCG CCCTCG chr16:30389628-30389708 40 1.82e-03 CGGAGGTCCC GGGGGGCG CTGGGCAGTG chr2:198669846-198669926 28 1.82e-03 ccgacgcggc ggggggcg AAGACGACCC chr7:5465579-5465659 47 1.82e-03 AGGCGGGGGA AGGGGGCC GTGTGTGGGG chr9:114937612-114937692 27 1.82e-03 CGAGGGAAGC GGGGGGCG CTGCGGGGTC chr19:52193207-52193287 36 1.82e-03 CGGGGCTTTG AGGGGTCA AGGGTGAGCC chr1:23543402-23543482 45 1.82e-03 ggggcccctc ggggggcg tcgcggtccc chr19:12949124-12949204 44 1.95e-03 CCCGCCGGGG TGGGGGCG CCAGGCGAGT chr14:23479464-23479544 18 1.95e-03 ACCCCGGAGT TGGGGGCG GGGGGGGCCC chr4:141174431-141174511 5 1.95e-03 gggg tgggggcg gCGAGACCCC chr19:4267819-4267899 50 1.95e-03 ATGGGGTGGG TGGGGGCG GCCTGCGACC chr19:45752122-45752202 28 1.95e-03 GGGAACGGGT TGGGGGCG CTCAGCCCCT chr19:791839-791919 40 2.10e-03 GGTGGGGAAA GAGGGTCA GGCTGGGGAG chr1:145588636-145588716 33 2.10e-03 GGTGAATGGT GGTGGTCT TGGCCAGGGA chr19:17496858-17496938 41 2.10e-03 GGCCGGGGGA GGTGGTCT CAGACCCACC chr1:145585483-145585563 51 2.54e-03 GTGGCCCCTG GGGGGGCC TTGAGGGAGG chr8:21924443-21924523 2 2.68e-03 g tgggggcc gcTTGGGAGT chr19:14586206-14586286 41 2.68e-03 GCACGCCCGC TGGGGGCC TGGAGTGGCA chr10:73407451-73407531 52 2.68e-03 acccaggggt tggggtca gccccgcctg chr10:25241770-25241850 50 2.71e-03 CCCCCTGCCG GATGGTCG CGTGCAGCCC chr12:72332629-72332709 14 2.86e-03 CTTCAGCACC AGGGTTCT GGACAGCGCC chr16:28502795-28502875 42 2.86e-03 TGCGCGCCCT GATGGTCC AACAGAGGGA chr6:29596536-29596616 17 3.30e-03 GGTGGGAGCT CAGGGTCT CCCAGCACCC -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif RGGGGKCB MEME-2 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr22:19706543-19706623 5.8e-06 35_[+2]_37 chr19:46142543-46142623 5.8e-06 60_[+2]_12 chr3:185541042-185541122 2.2e-05 70_[+2]_2 chr11:62324209-62324289 2.2e-05 32_[+2]_40 chr19:49399626-49399706 2.2e-05 44_[+2]_28 chr19:1194695-1194775 2.2e-05 45_[+2]_27 chr10:73468128-73468208 2.2e-05 59_[+2]_13 chr17:8649341-8649421 2.2e-05 31_[+2]_41 chr7:100184467-100184547 2.2e-05 42_[+2]_30 chr17:38242884-38242964 2.2e-05 34_[+2]_38 chr1:52195682-52195762 3.8e-05 4_[+2]_68 chr19:1767516-1767596 3.8e-05 12_[+2]_60 chr1:206837638-206837718 3.8e-05 5_[+2]_67 chr1:155053522-155053602 3.8e-05 59_[+2]_13 chr22:19953738-19953818 3.8e-05 45_[+2]_27 chr1:15757715-15757795 3.8e-05 29_[+2]_43 chr3:13696967-13697047 3.8e-05 58_[+2]_14 chr20:61071648-61071728 3.8e-05 65_[+2]_7 chr15:78423878-78423958 9.1e-05 31_[+2]_41 chr11:47421643-47421723 9.1e-05 32_[+2]_40 chr5:76787760-76787840 9.1e-05 7_[+2]_65 chr2:61922178-61922258 9.1e-05 71_[+2]_1 chr17:47074616-47074696 9.1e-05 57_[+2]_15 chr19:822111-822191 9.1e-05 40_[+2]_32 chrX:131119625-131119705 0.00011 19_[+2]_53 chr16:85286971-85287051 0.00011 53_[+2]_19 chr9:101867127-101867207 0.00011 50_[+2]_22 chr1:33338330-33338410 0.00011 33_[+2]_39 chr9:19230269-19230349 0.00017 26_[+2]_46 chr20:30795103-30795183 0.00017 42_[+2]_30 chr5:172199060-172199140 0.00017 2_[+2]_70 chr19:35605662-35605742 0.00017 53_[+2]_19 chr22:38198362-38198442 0.00023 19_[+2]_53 chr10:97804021-97804101 0.00023 38_[+2]_34 chr12:30848438-30848518 0.00023 32_[+2]_40 chr19:45287798-45287878 0.00023 46_[+2]_26 chr11:335842-335922 0.00026 37_[+2]_35 chr14:75762885-75762965 0.00026 17_[+2]_55 chr19:917844-917924 0.00043 19_[+2]_53 chr9:129622565-129622645 0.00043 15_[+2]_57 chr19:3307484-3307564 0.00043 27_[+2]_45 chr5:71616462-71616542 0.00043 36_[+2]_36 chr12:122241354-12224143 0.00043 41_[+2]_31 chr7:148396941-148397021 0.00043 50_[+2]_22 chr19:1267156-1267236 0.00043 33_[+2]_39 chr19:11200938-11201018 0.00043 31_[+2]_41 chr4:183727576-183727656 0.00043 25_[+2]_47 chr6:158244870-158244950 0.00043 56_[+2]_16 chr19:56904552-56904632 0.00043 39_[+2]_33 chr17:27071433-27071513 0.00043 28_[+2]_44 chr7:116503370-116503450 0.00043 67_[+2]_5 chr9:139566242-139566322 0.00043 59_[+2]_13 chr8:143751085-143751165 0.00043 23_[+2]_49 chr17:55055275-55055355 0.00043 48_[+2]_24 chr19:13274008-13274088 0.00043 33_[+2]_39 chr2:30370794-30370874 0.00043 49_[+2]_23 chr16:30933075-30933155 0.00043 66_[+2]_6 chr7:98476151-98476231 0.00043 54_[+2]_18 chr10:3088091-3088171 0.00043 23_[+2]_49 chr10:134266806-13426688 0.00043 60_[+2]_12 chr6:43726401-43726481 0.00043 60_[+2]_12 chr17:46599577-46599657 0.00052 33_[+2]_39 chr17:40826271-40826351 0.00052 61_[+2]_11 chr19:506913-506993 0.00052 40_[+2]_32 chr11:64948448-64948528 0.00052 8_[+2]_64 chr5:139077406-139077486 0.00052 48_[+2]_24 chr7:23511029-23511109 0.00052 38_[+2]_34 chr2:106020410-106020490 0.00052 42_[+2]_30 chr19:1401578-1401658 0.00052 72_[+2] chr19:39226706-39226786 0.00052 13_[+2]_59 chr2:139191906-139191986 0.00052 26_[+2]_46 chr4:128802409-128802489 0.00056 32_[+2]_40 chr19:14542902-14542982 0.00056 49_[+2]_23 chr11:65185728-65185808 0.00056 18_[+2]_54 chr19:17403187-17403267 0.00056 36_[+2]_36 chr9:130705245-130705325 0.00056 39_[+2]_33 chrX:153637746-153637826 0.00062 34_[+2]_38 chr16:475510-475590 0.00062 38_[+2]_34 chr6:32936690-32936770 0.00062 11_[+2]_61 chr7:6677450-6677530 0.00062 6_[+2]_66 chr1:11796623-11796703 0.00062 13_[+2]_59 chr22:30821674-30821754 0.00062 15_[+2]_57 chr11:63684044-63684124 0.00062 22_[+2]_50 chr19:14169951-14170031 0.00062 48_[+2]_24 chr20:36849592-36849672 0.00076 19_[+2]_53 chr10:76868586-76868666 0.00076 36_[+2]_36 chr1:1003638-1003718 0.00076 41_[+2]_31 chr19:11314648-11314728 0.00076 65_[+2]_7 chr2:20442148-20442228 0.00076 62_[+2]_10 chr2:64880477-64880557 0.00076 61_[+2]_11 chr5:79378789-79378869 0.00076 50_[+2]_22 chr1:84543557-84543637 0.00076 36_[+2]_36 chr11:2216344-2216424 0.00076 35_[+2]_37 chr20:52210676-52210756 0.00076 65_[+2]_7 chr21:43298823-43298903 0.00076 9_[+2]_63 chr7:134379240-134379320 0.00076 34_[+2]_38 chr11:63688711-63688791 0.00076 70_[+2]_2 chr17:71228778-71228858 0.00093 20_[+2]_52 chr10:81205490-81205570 0.00093 43_[+2]_29 chr1:54872385-54872465 0.00093 21_[+2]_51 chr12:56320876-56320956 0.00093 52_[+2]_20 chr4:6722096-6722176 0.00093 21_[+2]_51 chr22:38852088-38852168 0.00093 2_[+2]_70 chr3:128216824-128216904 0.00093 57_[+2]_15 chr11:63535768-63535848 0.00093 16_[+2]_56 chr7:100492622-100492702 0.00098 36_[+2]_36 chr9:132998589-132998669 0.00098 42_[+2]_30 chrX:39964421-39964501 0.00098 22_[+2]_50 chr11:64512683-64512763 0.001 12_[+2]_60 chr1:156023737-156023817 0.001 69_[+2]_3 chr19:7990124-7990204 0.0011 33_[+2]_39 chr2:176944716-176944796 0.0011 48_[+2]_24 chr18:19284242-19284322 0.0011 39_[+2]_33 chr1:919692-919772 0.0011 63_[+2]_9 chr19:18526032-18526112 0.0011 40_[+2]_32 chr4:1750540-1750620 0.0011 19_[+2]_53 chr19:34286322-34286402 0.0011 47_[+2]_25 chr20:62733500-62733580 0.0011 37_[+2]_35 chr12:2955200-2955280 0.0011 57_[+2]_15 chr4:184427150-184427230 0.0013 19_[+2]_53 chr10:75757476-75757556 0.0013 54_[+2]_18 chr11:46141402-46141482 0.0013 54_[+2]_18 chr11:65083122-65083202 0.0013 22_[+2]_50 chr7:101054689-101054769 0.0013 55_[+2]_17 chr2:239335594-239335674 0.0013 71_[+2]_1 chr7:5230248-5230328 0.0013 35_[+2]_37 chr19:4067608-4067688 0.0014 14_[+2]_58 chr6:112364993-112365073 0.0014 7_[+2]_65 chr12:48206728-48206808 0.0018 4_[+2]_68 chr8:141646112-141646192 0.0018 59_[+2]_13 chr1:150521703-150521783 0.0018 [+2]_72 chr13:77904013-77904093 0.0018 38_[+2]_34 chr16:57126886-57126966 0.0018 66_[+2]_6 chr16:30389628-30389708 0.0018 39_[+2]_33 chr2:198669846-198669926 0.0018 27_[+2]_45 chr7:5465579-5465659 0.0018 46_[+2]_26 chr9:114937612-114937692 0.0018 26_[+2]_46 chr19:52193207-52193287 0.0018 35_[+2]_37 chr1:23543402-23543482 0.0018 44_[+2]_28 chr19:12949124-12949204 0.002 43_[+2]_29 chr14:23479464-23479544 0.002 17_[+2]_55 chr4:141174431-141174511 0.002 4_[+2]_68 chr19:4267819-4267899 0.002 49_[+2]_23 chr19:45752122-45752202 0.002 27_[+2]_45 chr19:791839-791919 0.0021 39_[+2]_33 chr1:145588636-145588716 0.0021 32_[+2]_40 chr19:17496858-17496938 0.0021 40_[+2]_32 chr1:145585483-145585563 0.0025 50_[+2]_22 chr8:21924443-21924523 0.0027 1_[+2]_71 chr19:14586206-14586286 0.0027 40_[+2]_32 chr10:73407451-73407531 0.0027 51_[+2]_21 chr10:25241770-25241850 0.0027 49_[+2]_23 chr12:72332629-72332709 0.0029 13_[+2]_59 chr16:28502795-28502875 0.0029 41_[+2]_31 chr6:29596536-29596616 0.0033 16_[+2]_56 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif RGGGGKCB MEME-2 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF RGGGGKCB width=8 seqs=155 chr22:19706543-19706623 ( 36) AAGGGTCT 1 chr19:46142543-46142623 ( 61) AAGGGTCT 1 chr3:185541042-185541122 ( 71) AGGGGTCT 1 chr11:62324209-62324289 ( 33) AGGGGTCT 1 chr19:49399626-49399706 ( 45) AGGGGTCT 1 chr19:1194695-1194775 ( 46) AGGGGTCT 1 chr10:73468128-73468208 ( 60) AGGGGTCT 1 chr17:8649341-8649421 ( 32) AGGGGTCT 1 chr7:100184467-100184547 ( 43) AGGGGTCT 1 chr17:38242884-38242964 ( 35) AGGGGTCT 1 chr1:52195682-52195762 ( 5) GAGGGTCT 1 chr19:1767516-1767596 ( 13) GAGGGTCT 1 chr1:206837638-206837718 ( 6) GAGGGTCT 1 chr1:155053522-155053602 ( 60) GAGGGTCT 1 chr22:19953738-19953818 ( 46) GAGGGTCT 1 chr1:15757715-15757795 ( 30) GAGGGTCT 1 chr3:13696967-13697047 ( 59) GAGGGTCT 1 chr20:61071648-61071728 ( 66) GAGGGTCT 1 chr15:78423878-78423958 ( 32) GGGGGTCT 1 chr11:47421643-47421723 ( 33) GGGGGTCT 1 chr5:76787760-76787840 ( 8) GGGGGTCT 1 chr2:61922178-61922258 ( 72) GGGGGTCT 1 chr17:47074616-47074696 ( 58) GGGGGTCT 1 chr19:822111-822191 ( 41) GGGGGTCT 1 chrX:131119625-131119705 ( 20) TGGGGTCT 1 chr16:85286971-85287051 ( 54) TGGGGTCT 1 chr9:101867127-101867207 ( 51) TGGGGTCT 1 chr1:33338330-33338410 ( 34) TGGGGTCT 1 chr9:19230269-19230349 ( 27) AGGGGTCG 1 chr20:30795103-30795183 ( 43) AGGGGTCG 1 chr5:172199060-172199140 ( 3) AGGGGTCG 1 chr19:35605662-35605742 ( 54) AGGGGTCG 1 chr22:38198362-38198442 ( 20) GAGGGTCG 1 chr10:97804021-97804101 ( 39) GAGGGTCG 1 chr12:30848438-30848518 ( 33) GAGGGTCG 1 chr19:45287798-45287878 ( 47) GAGGGTCG 1 chr11:335842-335922 ( 38) AAGGGGCT 1 chr14:75762885-75762965 ( 18) AAGGGGCT 1 chr19:917844-917924 ( 20) AGGGGTCC 1 chr9:129622565-129622645 ( 16) GGGGGTCG 1 chr19:3307484-3307564 ( 28) GGGGGTCG 1 chr5:71616462-71616542 ( 37) GGGGGTCG 1 chr12:122241354-12224143 ( 42) GGGGGTCG 1 chr7:148396941-148397021 ( 51) GGGGGTCG 1 chr19:1267156-1267236 ( 34) AGGGGTCC 1 chr19:11200938-11201018 ( 32) AGGGGTCC 1 chr4:183727576-183727656 ( 26) AGGGGTCC 1 chr6:158244870-158244950 ( 57) GGGGGTCG 1 chr19:56904552-56904632 ( 40) AGGGGTCC 1 chr17:27071433-27071513 ( 29) AGGGGTCC 1 chr7:116503370-116503450 ( 68) GGGGGTCG 1 chr9:139566242-139566322 ( 60) AGGGGTCC 1 chr8:143751085-143751165 ( 24) GGGGGTCG 1 chr17:55055275-55055355 ( 49) AGGGGTCC 1 chr19:13274008-13274088 ( 34) GGGGGTCG 1 chr2:30370794-30370874 ( 50) GGGGGTCG 1 chr16:30933075-30933155 ( 67) GGGGGTCG 1 chr7:98476151-98476231 ( 55) GGGGGTCG 1 chr10:3088091-3088171 ( 24) AGGGGTCC 1 chr10:134266806-13426688 ( 61) GGGGGTCG 1 chr6:43726401-43726481 ( 61) AGGGGTCC 1 chr17:46599577-46599657 ( 34) AGGGGGCT 1 chr17:40826271-40826351 ( 62) TGGGGTCG 1 chr19:506913-506993 ( 41) AGGGGGCT 1 chr11:64948448-64948528 ( 9) AGGGGGCT 1 chr5:139077406-139077486 ( 49) AGGGGGCT 1 chr7:23511029-23511109 ( 39) TGGGGTCG 1 chr2:106020410-106020490 ( 43) TGGGGTCG 1 chr19:1401578-1401658 ( 73) TGGGGTCG 1 chr19:39226706-39226786 ( 14) TGGGGTCG 1 chr2:139191906-139191986 ( 27) AGGGGGCT 1 chr4:128802409-128802489 ( 33) GAGGGTCC 1 chr19:14542902-14542982 ( 50) GAGGGTCC 1 chr11:65185728-65185808 ( 19) GAGGGTCC 1 chr19:17403187-17403267 ( 37) GAGGGTCC 1 chr9:130705245-130705325 ( 40) GAGGGTCC 1 chrX:153637746-153637826 ( 35) GAGGGGCT 1 chr16:475510-475590 ( 39) GAGGGGCT 1 chr6:32936690-32936770 ( 12) GAGGGGCT 1 chr7:6677450-6677530 ( 7) GAGGGGCT 1 chr1:11796623-11796703 ( 14) GAGGGGCT 1 chr22:30821674-30821754 ( 16) GAGGGGCT 1 chr11:63684044-63684124 ( 23) TAGGGTCC 1 chr19:14169951-14170031 ( 49) GAGGGGCT 1 chr20:36849592-36849672 ( 20) TAGGGGCT 1 chr10:76868586-76868666 ( 37) GGGGGTCC 1 chr1:1003638-1003718 ( 42) GGGGGTCC 1 chr19:11314648-11314728 ( 66) GGGGGTCC 1 chr2:20442148-20442228 ( 63) GGGGGTCC 1 chr2:64880477-64880557 ( 62) GGGGGTCC 1 chr5:79378789-79378869 ( 51) GGGGGTCC 1 chr1:84543557-84543637 ( 37) GGGGGTCC 1 chr11:2216344-2216424 ( 36) GGGGGTCC 1 chr20:52210676-52210756 ( 66) GGGGGTCC 1 chr21:43298823-43298903 ( 10) GGGGGTCC 1 chr7:134379240-134379320 ( 35) TAGGGGCT 1 chr11:63688711-63688791 ( 71) GGGGGTCC 1 chr17:71228778-71228858 ( 21) GGGGGGCT 1 chr10:81205490-81205570 ( 44) TGGGGTCC 1 chr1:54872385-54872465 ( 22) GGGGGGCT 1 chr12:56320876-56320956 ( 53) TGGGGTCC 1 chr4:6722096-6722176 ( 22) TGGGGTCC 1 chr22:38852088-38852168 ( 3) GGGGGGCT 1 chr3:128216824-128216904 ( 58) TGGGGTCC 1 chr11:63535768-63535848 ( 17) GGGGGGCT 1 chr7:100492622-100492702 ( 37) TGGGGGCT 1 chr9:132998589-132998669 ( 43) TGGGGGCT 1 chrX:39964421-39964501 ( 23) TGGGGGCT 1 chr11:64512683-64512763 ( 13) AAGGGGCG 1 chr1:156023737-156023817 ( 70) AAGGGGCG 1 chr19:7990124-7990204 ( 34) AGGGGGCG 1 chr2:176944716-176944796 ( 49) AGGGGGCG 1 chr18:19284242-19284322 ( 40) AGGGGGCG 1 chr1:919692-919772 ( 64) AGGGGGCG 1 chr19:18526032-18526112 ( 41) AGGGGGCG 1 chr4:1750540-1750620 ( 20) AGGGGGCG 1 chr19:34286322-34286402 ( 48) AGGGGGCG 1 chr20:62733500-62733580 ( 38) AGGGGGCG 1 chr12:2955200-2955280 ( 58) AGGGGGCG 1 chr4:184427150-184427230 ( 20) GAGGGGCG 1 chr10:75757476-75757556 ( 55) GAGGGGCG 1 chr11:46141402-46141482 ( 55) GAGGGGCG 1 chr11:65083122-65083202 ( 23) GAGGGGCG 1 chr7:101054689-101054769 ( 56) GAGGGGCG 1 chr2:239335594-239335674 ( 72) GAGGGGCG 1 chr7:5230248-5230328 ( 36) GAGGGGCG 1 chr19:4067608-4067688 ( 15) TAGGGGCG 1 chr6:112364993-112365073 ( 8) TAGGGGCG 1 chr12:48206728-48206808 ( 5) GGGGGGCG 1 chr8:141646112-141646192 ( 60) GGGGGGCG 1 chr1:150521703-150521783 ( 1) GGGGGGCG 1 chr13:77904013-77904093 ( 39) GGGGGGCG 1 chr16:57126886-57126966 ( 67) GGGGGGCG 1 chr16:30389628-30389708 ( 40) GGGGGGCG 1 chr2:198669846-198669926 ( 28) GGGGGGCG 1 chr7:5465579-5465659 ( 47) AGGGGGCC 1 chr9:114937612-114937692 ( 27) GGGGGGCG 1 chr19:52193207-52193287 ( 36) AGGGGTCA 1 chr1:23543402-23543482 ( 45) GGGGGGCG 1 chr19:12949124-12949204 ( 44) TGGGGGCG 1 chr14:23479464-23479544 ( 18) TGGGGGCG 1 chr4:141174431-141174511 ( 5) TGGGGGCG 1 chr19:4267819-4267899 ( 50) TGGGGGCG 1 chr19:45752122-45752202 ( 28) TGGGGGCG 1 chr19:791839-791919 ( 40) GAGGGTCA 1 chr1:145588636-145588716 ( 33) GGTGGTCT 1 chr19:17496858-17496938 ( 41) GGTGGTCT 1 chr1:145585483-145585563 ( 51) GGGGGGCC 1 chr8:21924443-21924523 ( 2) TGGGGGCC 1 chr19:14586206-14586286 ( 41) TGGGGGCC 1 chr10:73407451-73407531 ( 52) TGGGGTCA 1 chr10:25241770-25241850 ( 50) GATGGTCG 1 chr12:72332629-72332709 ( 14) AGGGTTCT 1 chr16:28502795-28502875 ( 42) GATGGTCC 1 chr6:29596536-29596616 ( 17) CAGGGTCT 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif RGGGGKCB MEME-2 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 7.08541 E= 1.3e-030 116 -582 49 45 119 -1392 93 -1392 -1392 -1392 140 -240 -1392 -1392 144 -1392 -1392 -1392 143 -440 -1392 -1392 10 215 -1392 145 -1392 -1392 -275 -65 10 138 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif RGGGGKCB MEME-2 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 155 E= 1.3e-030 0.290323 0.006452 0.516129 0.187097 0.296774 0.000000 0.703226 0.000000 0.000000 0.000000 0.974194 0.025806 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.993548 0.006452 0.000000 0.000000 0.393548 0.606452 0.000000 1.000000 0.000000 0.000000 0.019355 0.232258 0.393548 0.354839 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif RGGGGKCB MEME-2 regular expression -------------------------------------------------------------------------------- [GA][GA]GGG[TG]C[GTC] -------------------------------------------------------------------------------- Time 9.22 secs. ******************************************************************************** ******************************************************************************** MOTIF TTGTTTTC MEME-3 width = 8 sites = 8 llr = 89 E-value = 1.7e+002 ******************************************************************************** -------------------------------------------------------------------------------- Motif TTGTTTTC MEME-3 Description -------------------------------------------------------------------------------- Simplified A 1::::1:: pos.-specific C 313::::a probability G ::6::::: matrix T 691aa9a: bits 2.9 ** * 2.6 ** * 2.4 **** 2.1 * **** Relative 1.8 * **** Entropy 1.5 * ***** (16.1 bits) 1.2 ** ***** 0.9 ** ***** 0.6 ** ***** 0.3 ******** 0.0 -------- Multilevel TTGTTTTC consensus C C sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTGTTTTC MEME-3 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr19:4067608-4067688 62 8.88e-07 GGGAGGGCGG TTGTTTTC CCGGCTTCGC chr7:116503370-116503450 33 8.88e-07 CTCCCCATAG TTGTTTTC TGCCCACGTT chr7:148396941-148397021 64 1.22e-06 GGTCGTCGCT TTTTTTTC CCTTAAGAT chr11:64512683-64512763 47 6.15e-06 GCTCGGGTTC CTGTTTTC GAGACAAACC chr17:40115174-40115254 14 6.15e-06 AGCATTGCAT CTGTTTTC ACCACCAAAG chr19:917844-917924 41 7.61e-06 CCAACCTCGA ATCTTTTC CCTGTGGTCC chr12:1772026-1772106 38 9.33e-06 GACCCTGCCT TTCTTATC GCGCATCGCC chr6:32936690-32936770 50 1.40e-05 CAGCACGGCT TCGTTTTC TGGGGGGGGG -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTGTTTTC MEME-3 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr19:4067608-4067688 8.9e-07 61_[+3]_11 chr7:116503370-116503450 8.9e-07 32_[+3]_40 chr7:148396941-148397021 1.2e-06 63_[+3]_9 chr11:64512683-64512763 6.2e-06 46_[+3]_26 chr17:40115174-40115254 6.2e-06 13_[+3]_59 chr19:917844-917924 7.6e-06 40_[+3]_32 chr12:1772026-1772106 9.3e-06 37_[+3]_35 chr6:32936690-32936770 1.4e-05 49_[+3]_23 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTGTTTTC MEME-3 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF TTGTTTTC width=8 seqs=8 chr19:4067608-4067688 ( 62) TTGTTTTC 1 chr7:116503370-116503450 ( 33) TTGTTTTC 1 chr7:148396941-148397021 ( 64) TTTTTTTC 1 chr11:64512683-64512763 ( 47) CTGTTTTC 1 chr17:40115174-40115254 ( 14) CTGTTTTC 1 chr19:917844-917924 ( 41) ATCTTTTC 1 chr12:1772026-1772106 ( 38) TTCTTATC 1 chr6:32936690-32936770 ( 50) TCGTTTTC 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTGTTTTC MEME-3 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 11.155 E= 1.7e+002 -6 -55 -965 219 -965 -154 -965 268 -965 -55 76 -13 -965 -965 -965 287 -965 -965 -965 287 -6 -965 -965 268 -965 -965 -965 287 -965 145 -965 -965 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTGTTTTC MEME-3 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 8 E= 1.7e+002 0.125000 0.250000 0.000000 0.625000 0.000000 0.125000 0.000000 0.875000 0.000000 0.250000 0.625000 0.125000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.125000 0.000000 0.000000 0.875000 0.000000 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTGTTTTC MEME-3 regular expression -------------------------------------------------------------------------------- [TC]T[GC]TTTTC -------------------------------------------------------------------------------- Time 12.49 secs. ******************************************************************************** ******************************************************************************** MOTIF AGAWCWAA MEME-4 width = 8 sites = 2 llr = 26 E-value = 7.7e+003 ******************************************************************************** -------------------------------------------------------------------------------- Motif AGAWCWAA MEME-4 Description -------------------------------------------------------------------------------- Simplified A a:a5:5aa pos.-specific C ::::a::: probability G :a:::::: matrix T :::5:5:: bits 2.9 * * ** 2.6 * * ** 2.4 * * ** 2.1 * * ** Relative 1.8 * ** *** Entropy 1.5 ******** (18.5 bits) 1.2 ******** 0.9 ******** 0.6 ******** 0.3 ******** 0.0 -------- Multilevel AGAACAAA consensus T T sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AGAWCWAA MEME-4 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr20:36849592-36849672 43 6.48e-07 GACCCGCTGC AGAACAAA CGCCCACAGC chr19:46142543-46142623 13 2.73e-06 GTGAAACCTG AGATCTAA GCCCCGGGAG -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AGAWCWAA MEME-4 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr20:36849592-36849672 6.5e-07 42_[+4]_30 chr19:46142543-46142623 2.7e-06 12_[+4]_60 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AGAWCWAA MEME-4 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF AGAWCWAA width=8 seqs=2 chr20:36849592-36849672 ( 43) AGAACAAA 1 chr19:46142543-46142623 ( 13) AGATCTAA 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AGAWCWAA MEME-4 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 13.1555 E= 7.7e+003 293 -765 -765 -765 -765 -765 144 -765 293 -765 -765 -765 194 -765 -765 187 -765 145 -765 -765 194 -765 -765 187 293 -765 -765 -765 293 -765 -765 -765 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AGAWCWAA MEME-4 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 2 E= 7.7e+003 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.500000 0.000000 0.000000 0.500000 0.000000 1.000000 0.000000 0.000000 0.500000 0.000000 0.000000 0.500000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AGAWCWAA MEME-4 regular expression -------------------------------------------------------------------------------- AGA[AT]C[AT]AA -------------------------------------------------------------------------------- Time 15.78 secs. ******************************************************************************** ******************************************************************************** MOTIF CTCTCAAA MEME-5 width = 8 sites = 4 llr = 48 E-value = 9.2e+003 ******************************************************************************** -------------------------------------------------------------------------------- Motif CTCTCAAA MEME-5 Description -------------------------------------------------------------------------------- Simplified A :::3:aa8 pos.-specific C a:a:a::: probability G :::::::: matrix T :a:8:::3 bits 2.9 * ** 2.6 * ** 2.4 * ** 2.1 * * *** Relative 1.8 * * *** Entropy 1.5 ******** (17.3 bits) 1.2 ******** 0.9 ******** 0.6 ******** 0.3 ******** 0.0 -------- Multilevel CTCTCAAA consensus A T sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTCTCAAA MEME-5 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr16:66638797-66638877 27 2.01e-06 TTCCTCTGCT CTCTCAAA GGCCGCCTCC chr19:17496858-17496938 67 2.01e-06 CCCTGTCCGA CTCTCAAA CTCTGG chr7:116503370-116503450 4 3.91e-06 TTG CTCACAAA AAGACGACCC chr12:72332629-72332709 62 6.02e-06 ACGCCCCTTC CTCTCAAT CTCCGCCAGC -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTCTCAAA MEME-5 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr16:66638797-66638877 2e-06 26_[+5]_46 chr19:17496858-17496938 2e-06 66_[+5]_6 chr7:116503370-116503450 3.9e-06 3_[+5]_69 chr12:72332629-72332709 6e-06 61_[+5]_11 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTCTCAAA MEME-5 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF CTCTCAAA width=8 seqs=4 chr16:66638797-66638877 ( 27) CTCTCAAA 1 chr19:17496858-17496938 ( 67) CTCTCAAA 1 chr7:116503370-116503450 ( 4) CTCACAAA 1 chr12:72332629-72332709 ( 62) CTCTCAAT 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTCTCAAA MEME-5 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 12.1553 E= 9.2e+003 -865 145 -865 -865 -865 -865 -865 287 -865 145 -865 -865 94 -865 -865 245 -865 145 -865 -865 294 -865 -865 -865 294 -865 -865 -865 252 -865 -865 87 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTCTCAAA MEME-5 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 4 E= 9.2e+003 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 0.250000 0.000000 0.000000 0.750000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.750000 0.000000 0.000000 0.250000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTCTCAAA MEME-5 regular expression -------------------------------------------------------------------------------- CTC[TA]CAA[AT] -------------------------------------------------------------------------------- Time 19.00 secs. ******************************************************************************** ******************************************************************************** SUMMARY OF MOTIFS ******************************************************************************** -------------------------------------------------------------------------------- Combined block diagrams: non-overlapping sites with p-value < 0.0001 -------------------------------------------------------------------------------- SEQUENCE NAME COMBINED P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr19:45752122-45752202 7.80e-03 58_[+1(7.56e-05)]_14 chr19:35605662-35605742 3.87e-03 80 chr19:822111-822191 2.02e-01 31_[+2(9.08e-05)]_1_[+2(9.08e-05)]_\ 32 chr19:45287798-45287878 9.26e-03 80 chr1:33338330-33338410 1.07e-01 80 chr9:130705245-130705325 2.46e-01 80 chr19:4267819-4267899 7.21e-03 80 chr12:30848438-30848518 2.91e-03 43_[+1(7.56e-05)]_29 chr16:3011946-3012026 6.79e-02 80 chr11:2951697-2951777 1.68e-01 21_[+1(5.59e-05)]_51 chr1:1951115-1951195 4.79e-01 80 chr6:43726401-43726481 1.78e-01 80 chr5:180594972-180595052 1.25e-01 80 chr20:61071648-61071728 2.86e-02 65_[+2(3.84e-05)]_7 chr9:140190032-140190112 8.39e-01 80 chr17:38242884-38242964 1.56e-03 34_[+2(2.21e-05)]_38 chr11:63688711-63688791 3.79e-01 80 chr3:13696967-13697047 1.28e-01 58_[+2(3.84e-05)]_14 chr7:5230248-5230328 7.44e-02 52_[+1(5.59e-05)]_20 chr10:97804021-97804101 1.00e-01 80 chr19:17496858-17496938 1.21e-03 66_[+5(2.01e-06)]_6 chr15:79103977-79104057 5.62e-01 80 chr6:131384430-131384510 3.34e-01 80 chr2:139191906-139191986 1.34e-01 80 chr19:39467328-39467408 1.10e-01 80 chr7:134379240-134379320 8.08e-03 51_[+1(5.59e-05)]_21 chr11:63535768-63535848 4.29e-01 80 chr19:1001742-1001822 1.26e-01 80 chr19:46142543-46142623 2.81e-05 12_[+4(2.73e-06)]_40_[+2(5.77e-06)]_\ 12 chr8:134581937-134582017 7.93e-02 80 chr11:69616491-69616571 1.24e-01 80 chr19:39226706-39226786 4.03e-02 80 chr10:134266806-13426688 2.54e-01 80 chr17:47074616-47074696 5.85e-02 57_[+2(9.08e-05)]_15 chr9:101867127-101867207 4.04e-02 80 chr7:87505125-87505205 1.41e-01 80 chr17:78955227-78955307 9.92e-01 80 chr10:73407451-73407531 1.75e-01 80 chr22:42322223-42322303 7.25e-01 80 chr1:156023737-156023817 3.33e-01 80 chr7:77326387-77326467 9.38e-01 80 chrX:39969131-39969211 7.47e-01 80 chr19:14169951-14170031 1.47e-01 80 chr1:1532718-1532798 2.41e-01 80 chr2:238384132-238384212 1.69e-01 22_[+1(5.59e-05)]_50 chrX:39964421-39964501 9.26e-02 80 chr21:43298823-43298903 8.07e-02 80 chr20:52210676-52210756 2.46e-01 80 chr19:14143122-14143202 1.07e-02 51_[+1(5.59e-05)]_21 chr16:3068224-3068304 1.03e-01 34_[+1(5.59e-05)]_38 chr10:3088091-3088171 9.30e-02 80 chr17:35850299-35850379 4.40e-01 80 chr3:53230114-53230194 1.84e-01 80 chr7:100184467-100184547 1.20e-02 42_[+2(2.21e-05)]_30 chr11:2216344-2216424 4.34e-02 80 chr1:84543557-84543637 3.56e-01 80 chr17:1531615-1531695 2.62e-03 42_[+1(5.59e-05)]_30 chr19:14586206-14586286 6.09e-02 58_[+1(5.59e-05)]_14 chr1:156355485-156355565 1.37e-02 80 chr16:85325254-85325334 3.72e-02 36_[+1(5.59e-05)]_36 chr17:79935770-79935850 6.16e-01 80 chr17:40610727-40610807 3.19e-01 80 chr1:145588636-145588716 4.83e-02 80 chr12:2955200-2955280 2.94e-02 80 chr17:8649341-8649421 1.85e-01 31_[+2(2.21e-05)]_41 chr10:73468128-73468208 5.85e-03 59_[+2(2.21e-05)]_13 chr3:128216824-128216904 6.34e-01 80 chr17:40115174-40115254 4.60e-05 13_[+3(6.15e-06)]_31_[+1(5.59e-05)]_\ 20 chr6:29596536-29596616 6.32e-01 80 chr14:75762885-75762965 9.82e-02 80 chr4:141174431-141174511 5.90e-02 14_[+1(5.59e-05)]_58 chr16:89985130-89985210 4.56e-01 80 chr7:98476151-98476231 7.19e-01 80 chr13:27746262-27746342 1.52e-01 39_[+1(5.59e-05)]_33 chr7:1704418-1704498 6.66e-01 80 chr2:61922178-61922258 2.74e-01 49_[+2(9.08e-05)]_14_[+2(9.08e-05)]_\ 1 chr5:79378789-79378869 2.79e-01 80 chr2:64880477-64880557 2.00e-01 80 chr1:15757715-15757795 5.57e-03 29_[+2(3.84e-05)]_43 chr1:39283944-39284024 6.37e-02 80 chr3:99595083-99595163 4.15e-01 80 chr15:37393999-37394079 6.63e-01 80 chr17:43209414-43209494 4.28e-01 80 chr16:30933075-30933155 3.56e-02 80 chr19:3358741-3358821 5.83e-01 80 chr3:196756700-196756780 7.55e-01 80 chr20:62733500-62733580 3.31e-01 80 chr11:63684044-63684124 2.66e-02 80 chr9:132998589-132998669 4.25e-01 80 chr19:14590977-14591057 3.64e-01 80 chr19:1672161-1672241 2.92e-01 80 chrX:1573182-1573262 3.41e-01 80 chr9:32551109-32551189 1.15e-01 80 chr19:1401578-1401658 6.49e-01 80 chr2:113239527-113239607 3.21e-01 80 chr5:172199060-172199140 1.58e-01 80 chr6:99872724-99872804 1.17e-01 80 chr11:2913451-2913531 3.99e-01 80 chr2:30370794-30370874 3.92e-01 80 chr12:1772026-1772106 1.20e-03 37_[+3(9.33e-06)]_35 chr19:13274008-13274088 3.12e-01 80 chr17:55055275-55055355 1.64e-01 80 chr16:85286971-85287051 3.89e-02 80 chr2:47499674-47499754 5.52e-01 80 chr10:82295663-82295743 4.93e-02 80 chr2:106020410-106020490 5.92e-02 80 chr2:20442148-20442228 6.53e-01 80 chr19:11314648-11314728 2.28e-01 80 chr19:17650077-17650157 5.86e-01 80 chr1:23543402-23543482 5.58e-01 80 chr22:19953738-19953818 2.64e-02 45_[+2(3.84e-05)]_27 chr5:133332512-133332592 1.80e-02 55_[+1(5.59e-05)]_17 chr14:23479464-23479544 3.16e-01 80 chr14:105266680-10526676 3.55e-01 80 chr22:31481295-31481375 4.98e-01 80 chrX:131119625-131119705 1.00e-03 80 chr8:143751085-143751165 3.51e-01 80 chr7:100492622-100492702 4.93e-01 80 chr19:1194695-1194775 1.69e-05 15_[+3(5.00e-05)]_22_[+2(2.21e-05)]_\ 4_[+1(7.56e-05)]_15 chr17:37331334-37331414 2.66e-01 80 chr16:66638797-66638877 1.13e-03 26_[+5(2.01e-06)]_46 chr6:13710993-13711073 1.18e-01 80 chr9:101077907-101077987 1.17e-01 80 chr10:977994-978074 2.59e-02 45_[+1(7.56e-05)]_27 chr11:64512683-64512763 6.53e-04 46_[+3(6.15e-06)]_26 chr2:239335594-239335674 1.05e-01 80 chr9:139566242-139566322 2.90e-01 80 chr19:18169393-18169473 2.50e-01 80 chr7:101458883-101458963 4.77e-01 80 chr7:116503370-116503450 6.05e-08 3_[+5(3.91e-06)]_21_[+3(8.88e-07)]_\ 40 chr7:101054689-101054769 2.66e-01 80 chr19:49399626-49399706 1.88e-03 44_[+2(2.21e-05)]_28 chr19:34286322-34286402 3.91e-01 80 chr1:1003638-1003718 2.21e-03 80 chr9:77386011-77386091 4.01e-01 80 chr11:65083122-65083202 2.72e-02 33_[+1(5.59e-05)]_39 chr19:12949124-12949204 2.70e-01 80 chr19:52193207-52193287 8.58e-01 80 chr17:30469318-30469398 6.75e-01 80 chr6:112364993-112365073 4.94e-02 80 chr10:76868586-76868666 1.25e-01 80 chr7:157092599-157092679 1.68e-01 80 chr9:114937612-114937692 6.57e-01 80 chr7:23511029-23511109 1.42e-01 80 chr7:14029418-14029498 9.11e-01 80 chr4:1750540-1750620 2.41e-01 80 chr17:27071433-27071513 1.59e-01 80 chr1:26946858-26946938 1.73e-01 80 chr19:18526032-18526112 6.84e-01 80 chr5:139077406-139077486 1.99e-02 80 chr11:46141402-46141482 1.62e-01 80 chr19:56904552-56904632 1.80e-03 17_[+1(5.59e-05)]_55 chr11:64948448-64948528 2.59e-01 80 chr6:158244870-158244950 1.20e-01 80 chr7:5465579-5465659 8.38e-01 80 chr19:791839-791919 2.24e-01 80 chr22:38852088-38852168 1.36e-01 80 chr11:62324209-62324289 7.42e-03 32_[+2(2.21e-05)]_40 chr22:30821674-30821754 3.33e-01 80 chr14:69618388-69618468 3.57e-01 80 chr1:155053522-155053602 1.95e-02 29_[+2(3.84e-05)]_22_[+2(3.84e-05)]_\ 13 chr1:11796623-11796703 6.94e-01 80 chr19:4067608-4067688 7.36e-03 61_[+3(8.88e-07)]_11 chr5:76787760-76787840 2.75e-01 7_[+2(9.08e-05)]_65 chr4:183727576-183727656 3.04e-01 80 chr16:230365-230445 7.20e-01 80 chr1:153957945-153958025 8.11e-04 26_[+1(5.59e-05)]_46 chr14:102983342-10298342 6.26e-01 80 chr19:45931064-45931144 5.34e-02 80 chr19:11200938-11201018 4.65e-02 80 chr19:1267156-1267236 2.47e-02 50_[+1(5.59e-05)]_22 chr5:76011849-76011929 1.72e-01 80 chr7:148396941-148397021 1.26e-03 63_[+3(1.22e-06)]_9 chr10:25241770-25241850 4.66e-01 80 chr7:6677450-6677530 4.38e-02 80 chr19:954862-954942 1.03e-01 80 chr2:25599736-25599816 9.17e-02 52_[+1(5.59e-05)]_20 chr19:17403187-17403267 1.38e-01 80 chr16:28502795-28502875 8.52e-02 80 chr1:41826907-41826987 3.70e-01 80 chr15:41166012-41166092 7.86e-01 80 chr4:184020297-184020377 4.30e-01 80 chr1:919692-919772 5.85e-01 80 chr16:90085990-90086070 7.88e-01 80 chr11:335842-335922 2.88e-01 80 chr2:198669846-198669926 3.46e-01 80 chr16:30389628-30389708 8.11e-01 80 chr4:1580984-1581064 9.22e-01 80 chr11:47421643-47421723 2.56e-01 32_[+2(9.08e-05)]_40 chr12:122241354-12224143 1.73e-01 80 chr15:78423878-78423958 3.42e-02 31_[+2(9.08e-05)]_41 chr5:71616462-71616542 2.09e-02 80 chr8:21924443-21924523 9.16e-01 80 chr16:57126886-57126966 8.15e-01 80 chr1:206837638-206837718 5.95e-04 5_[+2(3.84e-05)]_67 chr18:19284242-19284322 5.76e-02 80 chr20:36849592-36849672 4.44e-04 42_[+4(6.48e-07)]_30 chr3:185541042-185541122 2.59e-02 9_[+2(9.08e-05)]_53_[+2(2.21e-05)]_\ 2 chr11:65185728-65185808 1.03e-02 80 chrX:153031844-153031924 5.67e-02 80 chr19:1767516-1767596 1.20e-02 12_[+2(3.84e-05)]_60 chr20:30795103-30795183 9.06e-03 80 chr7:86689107-86689187 4.59e-01 80 chr22:39915990-39916070 6.05e-02 52_[+1(5.59e-05)]_20 chr4:6722096-6722176 6.98e-01 80 chr17:27921268-27921348 1.74e-02 31_[+1(7.56e-05)]_41 chr6:32936690-32936770 5.78e-03 49_[+3(1.40e-05)]_23 chr2:209119094-209119174 2.48e-02 80 chr1:33207191-33207271 2.44e-01 80 chr1:145585483-145585563 5.65e-01 80 chr12:56652205-56652285 1.68e-01 80 chr13:77904013-77904093 7.39e-01 80 chr4:6894220-6894300 2.17e-02 58_[+3(5.00e-05)]_14 chr15:40763076-40763156 2.73e-01 80 chr16:1463771-1463851 8.20e-01 80 chr1:150521703-150521783 8.73e-01 80 chr2:176944716-176944796 3.59e-01 80 chr9:19230269-19230349 3.27e-01 80 chr19:7990124-7990204 3.82e-03 10_[+1(5.59e-05)]_62 chr16:475510-475590 4.78e-02 80 chr20:48330532-48330612 1.60e-01 80 chr8:141646112-141646192 9.68e-02 80 chr19:506913-506993 2.29e-01 80 chr12:56320876-56320956 9.79e-02 80 chr22:38198362-38198442 2.15e-01 80 chr1:54872385-54872465 7.74e-02 80 chr10:81205490-81205570 4.86e-01 80 chrX:153637746-153637826 6.85e-03 53_[+1(5.59e-05)]_19 chr19:3307484-3307564 1.74e-01 80 chr10:75757476-75757556 1.03e-02 24_[+1(5.59e-05)]_48 chr1:52195682-52195762 4.55e-02 4_[+2(3.84e-05)]_68 chr19:14542902-14542982 3.79e-04 68_[+4(4.46e-05)]_4 chr17:49244569-49244649 6.22e-02 80 chr17:36762759-36762839 8.06e-01 80 chr12:48206728-48206808 3.59e-01 80 chr12:111847777-11184785 2.77e-01 80 chr17:71228778-71228858 3.10e-01 80 chr4:184427150-184427230 2.89e-01 80 chr22:19706543-19706623 8.84e-03 35_[+2(5.77e-06)]_37 chr9:115096046-115096126 2.91e-02 62_[+1(7.56e-05)]_10 chr17:73852091-73852171 4.02e-01 80 chr17:40826271-40826351 9.54e-02 80 chr1:19734335-19734415 1.06e-03 16_[+1(5.59e-05)]_34_[+3(6.95e-05)]_\ 14 chr17:46599577-46599657 6.45e-02 80 chr12:72332629-72332709 2.27e-03 61_[+5(6.02e-06)]_11 chr4:128802409-128802489 1.63e-02 80 chr9:129622565-129622645 8.66e-03 80 chr3:57993942-57994022 8.16e-01 80 chr19:917844-917924 2.02e-03 40_[+3(7.61e-06)]_32 chr19:18705233-18705313 7.42e-01 80 -------------------------------------------------------------------------------- ******************************************************************************** ******************************************************************************** Stopped because requested number of motifs (5) found. ******************************************************************************** CPU: c22n08.farnam.hpc.yale.internal ********************************************************************************