******************************************************************************** MEME - Motif discovery tool ******************************************************************************** MEME version 5.3.3 (Release date: Sun Feb 7 15:39:52 2021 -0800) For further information on how to interpret these results please access https://meme-suite.org/meme. To get a copy of the MEME Suite software please access https://meme-suite.org. ******************************************************************************** ******************************************************************************** REFERENCE ******************************************************************************** If you use this program in your research, please cite: Timothy L. Bailey and Charles Elkan, "Fitting a mixture model by expectation maximization to discover motifs in biopolymers", Proceedings of the Second International Conference on Intelligent Systems for Molecular Biology, pp. 28-36, AAAI Press, Menlo Park, California, 1994. ******************************************************************************** ******************************************************************************** TRAINING SET ******************************************************************************** PRIMARY SEQUENCES= ../result/final_prediction/K562/fasta/RankLinear0.6_40/ZBED1.fasta CONTROL SEQUENCES= --none-- ALPHABET= ACGT Sequence name Weight Length Sequence name Weight Length ------------- ------ ------ ------------- ------ ------ chr22:36424506-36424586 1.0000 80 chr2:169309455-169309535 1.0000 80 chr19:46438646-46438726 1.0000 80 chr16:87032632-87032712 1.0000 80 chr19:40029909-40029989 1.0000 80 chr1:25943656-25943736 1.0000 80 chr8:143645385-143645465 1.0000 80 chr11:71098941-71099021 1.0000 80 chr11:27948566-27948646 1.0000 80 chr19:54641705-54641785 1.0000 80 chr2:122494677-122494757 1.0000 80 chr19:18896798-18896878 1.0000 80 chr10:105154074-10515415 1.0000 80 chr21:47745319-47745399 1.0000 80 chr16:19343228-19343308 1.0000 80 chr5:1193265-1193345 1.0000 80 chr7:27824134-27824214 1.0000 80 chr6:158958627-158958707 1.0000 80 chr18:23669696-23669776 1.0000 80 chr16:1001167-1001247 1.0000 80 chr1:153895967-153896047 1.0000 80 chr1:180823717-180823797 1.0000 80 chr19:10974204-10974284 1.0000 80 chr4:2366533-2366613 1.0000 80 chr1:38731441-38731521 1.0000 80 chr19:3737990-3738070 1.0000 80 chr14:105267672-10526775 1.0000 80 chr13:41976858-41976938 1.0000 80 chr17:2527840-2527920 1.0000 80 chr16:75600822-75600902 1.0000 80 chr22:46964086-46964166 1.0000 80 chr4:57396768-57396848 1.0000 80 chr11:134435422-13443550 1.0000 80 chr5:96038718-96038798 1.0000 80 chr6:3157139-3157219 1.0000 80 chr12:124972188-12497226 1.0000 80 chr16:1000881-1000961 1.0000 80 chr19:14625404-14625484 1.0000 80 chr19:53988890-53988970 1.0000 80 chr1:247634288-247634368 1.0000 80 chr10:134479614-13447969 1.0000 80 chr6:7675690-7675770 1.0000 80 chr12:131715801-13171588 1.0000 80 chr19:18451418-18451498 1.0000 80 chr6:31786053-31786133 1.0000 80 chr1:184723497-184723577 1.0000 80 chr15:73669892-73669972 1.0000 80 chr10:71667306-71667386 1.0000 80 chr5:149380486-149380566 1.0000 80 chr17:74637884-74637964 1.0000 80 chr1:154967211-154967291 1.0000 80 chr6:170407383-170407463 1.0000 80 chr4:140097478-140097558 1.0000 80 chr7:155102407-155102487 1.0000 80 chr5:149957845-149957925 1.0000 80 chr7:151624774-151624854 1.0000 80 chr1:113162949-113163029 1.0000 80 chr8:39393131-39393211 1.0000 80 chr5:176738786-176738866 1.0000 80 chr16:46865275-46865355 1.0000 80 chr17:25410696-25410776 1.0000 80 chr8:143644476-143644556 1.0000 80 chr3:58984368-58984448 1.0000 80 chr13:61158772-61158852 1.0000 80 chr4:187459257-187459337 1.0000 80 chr19:11435050-11435130 1.0000 80 chrX:64254582-64254662 1.0000 80 chr1:6053849-6053929 1.0000 80 chr4:100870649-100870729 1.0000 80 chr9:119233504-119233584 1.0000 80 chr6:31785837-31785917 1.0000 80 chr17:62971601-62971681 1.0000 80 chr12:112546650-11254673 1.0000 80 chr19:36630567-36630647 1.0000 80 chr7:155094964-155095044 1.0000 80 chr6:14864260-14864340 1.0000 80 chr21:47673532-47673612 1.0000 80 chr12:6641845-6641925 1.0000 80 chr16:68298321-68298401 1.0000 80 chr22:19702364-19702444 1.0000 80 chr9:135870069-135870149 1.0000 80 chr20:37518649-37518729 1.0000 80 chr6:31798361-31798441 1.0000 80 chr6:26140626-26140706 1.0000 80 chr9:127998696-127998776 1.0000 80 chr11:65195884-65195964 1.0000 80 chr3:48956164-48956244 1.0000 80 chr4:67206196-67206276 1.0000 80 chr13:21099342-21099422 1.0000 80 chr8:145129275-145129355 1.0000 80 chr2:152617051-152617131 1.0000 80 chr7:151000918-151000998 1.0000 80 chr20:60495000-60495080 1.0000 80 chr16:89787714-89787794 1.0000 80 chr1:222885459-222885539 1.0000 80 chr17:2304873-2304953 1.0000 80 chr17:18967101-18967181 1.0000 80 chr9:14525975-14526055 1.0000 80 chr5:77075013-77075093 1.0000 80 chr8:101962757-101962837 1.0000 80 chr20:30467646-30467726 1.0000 80 chr17:57920564-57920644 1.0000 80 chr18:59854213-59854293 1.0000 80 chr16:14724260-14724340 1.0000 80 chr17:73772635-73772715 1.0000 80 chr1:145443016-145443096 1.0000 80 chr11:65269120-65269200 1.0000 80 chr1:154909738-154909818 1.0000 80 chrX:65242028-65242108 1.0000 80 chr2:48010334-48010414 1.0000 80 chr1:36023592-36023672 1.0000 80 chr17:57919943-57920023 1.0000 80 chr21:35573876-35573956 1.0000 80 chr19:50836718-50836798 1.0000 80 chr16:57716832-57716912 1.0000 80 chr19:11201253-11201333 1.0000 80 chr3:182696418-182696498 1.0000 80 chr6:31799485-31799565 1.0000 80 chr19:45972746-45972826 1.0000 80 chr17:56743892-56743972 1.0000 80 chr7:151008747-151008827 1.0000 80 chr11:76838515-76838595 1.0000 80 chr6:26215989-26216069 1.0000 80 chr2:23698908-23698988 1.0000 80 chr1:160990819-160990899 1.0000 80 chr1:149215151-149215231 1.0000 80 chr17:55631081-55631161 1.0000 80 chr17:57919705-57919785 1.0000 80 chrX:154255419-154255499 1.0000 80 chr11:61731544-61731624 1.0000 80 chr12:50677197-50677277 1.0000 80 chr10:11911279-11911359 1.0000 80 chr5:70882896-70882976 1.0000 80 chr6:28688439-28688519 1.0000 80 chr7:138145730-138145810 1.0000 80 chr11:120107452-12010753 1.0000 80 chr3:72924737-72924817 1.0000 80 chr8:112052397-112052477 1.0000 80 chr8:8194470-8194550 1.0000 80 chr15:75052786-75052866 1.0000 80 chr2:145116805-145116885 1.0000 80 chr19:48996360-48996440 1.0000 80 chr13:42570250-42570330 1.0000 80 chr16:4357900-4357980 1.0000 80 chr11:117997321-11799740 1.0000 80 chr3:13044222-13044302 1.0000 80 chr22:30840951-30841031 1.0000 80 chr8:74790254-74790334 1.0000 80 chr3:194354375-194354455 1.0000 80 chr9:127997668-127997748 1.0000 80 chr1:247634513-247634593 1.0000 80 chr16:9085961-9086041 1.0000 80 chr7:75472493-75472573 1.0000 80 chr8:117614900-117614980 1.0000 80 chr11:61730838-61730918 1.0000 80 chr14:23120349-23120429 1.0000 80 chr6:27100297-27100377 1.0000 80 chr17:74351148-74351228 1.0000 80 chr15:66923217-66923297 1.0000 80 chr8:125827857-125827937 1.0000 80 chr16:998202-998282 1.0000 80 chr11:65270570-65270650 1.0000 80 chrX:53711120-53711200 1.0000 80 chr1:148604882-148604962 1.0000 80 chr15:73669388-73669468 1.0000 80 chrX:153191264-153191344 1.0000 80 chr2:108363190-108363270 1.0000 80 chr1:207779228-207779308 1.0000 80 chr5:95064995-95065075 1.0000 80 chr17:76136849-76136929 1.0000 80 chr22:39189836-39189916 1.0000 80 chr1:14762202-14762282 1.0000 80 chr15:45019333-45019413 1.0000 80 chr11:18127528-18127608 1.0000 80 chr7:2272559-2272639 1.0000 80 chr3:42642314-42642394 1.0000 80 chr3:193660509-193660589 1.0000 80 chr1:247634788-247634868 1.0000 80 chr7:75933921-75934001 1.0000 80 chr2:97202931-97203011 1.0000 80 chr2:30884200-30884280 1.0000 80 chr6:16215632-16215712 1.0000 80 chr3:4345267-4345347 1.0000 80 chr9:108457410-108457490 1.0000 80 chr3:151986705-151986785 1.0000 80 chr19:11200156-11200236 1.0000 80 chr6:26235018-26235098 1.0000 80 chr19:40931849-40931929 1.0000 80 chr17:41438566-41438646 1.0000 80 chr12:104342714-10434279 1.0000 80 chr6:31798817-31798897 1.0000 80 chr6:14118108-14118188 1.0000 80 chr1:149514186-149514266 1.0000 80 chr11:65272814-65272894 1.0000 80 chr6:15211425-15211505 1.0000 80 chr19:51640355-51640435 1.0000 80 chr6:28188512-28188592 1.0000 80 chr16:77756447-77756527 1.0000 80 chr5:95404093-95404173 1.0000 80 chr3:72057923-72058003 1.0000 80 chr11:121097358-12109743 1.0000 80 chr14:102545511-10254559 1.0000 80 chr6:26158528-26158608 1.0000 80 chr4:185115183-185115263 1.0000 80 chr11:65191287-65191367 1.0000 80 chr5:10262628-10262708 1.0000 80 chrX:153629576-153629656 1.0000 80 chr1:228327765-228327845 1.0000 80 chr11:62618998-62619078 1.0000 80 chr1:46908583-46908663 1.0000 80 chr14:51135344-51135424 1.0000 80 chr6:27776203-27776283 1.0000 80 chr1:145440371-145440451 1.0000 80 chr11:65271820-65271900 1.0000 80 chr6:31795578-31795658 1.0000 80 chr4:164164909-164164989 1.0000 80 chr6:27101694-27101774 1.0000 80 chr1:149859141-149859221 1.0000 80 chr7:149119424-149119504 1.0000 80 chr1:147735883-147735963 1.0000 80 chr12:54679891-54679971 1.0000 80 chr4:7599120-7599200 1.0000 80 chr2:9893585-9893665 1.0000 80 chr4:6927318-6927398 1.0000 80 chr5:43484497-43484577 1.0000 80 chr3:71922483-71922563 1.0000 80 chr16:1001869-1001949 1.0000 80 chr6:170407594-170407674 1.0000 80 chr6:26123956-26124036 1.0000 80 chr2:182757346-182757426 1.0000 80 chr17:40785238-40785318 1.0000 80 chr22:21011045-21011125 1.0000 80 chr5:142571410-142571490 1.0000 80 chr12:104324261-10432434 1.0000 80 chr16:68119331-68119411 1.0000 80 chr6:52350813-52350893 1.0000 80 chr10:74036381-74036461 1.0000 80 chr19:5309121-5309201 1.0000 80 chr3:52162253-52162333 1.0000 80 chr1:203595661-203595741 1.0000 80 chr19:56698356-56698436 1.0000 80 chr6:37143778-37143858 1.0000 80 chr14:102546688-10254676 1.0000 80 chr18:2655734-2655814 1.0000 80 chr6:68589143-68589223 1.0000 80 chr1:76262404-76262484 1.0000 80 chr4:154713484-154713564 1.0000 80 chr18:21002897-21002977 1.0000 80 chr10:557081-557161 1.0000 80 chr8:143645584-143645664 1.0000 80 ******************************************************************************** ******************************************************************************** COMMAND LINE SUMMARY ******************************************************************************** This information can also be useful in the event you wish to report a problem with the MEME software. command: meme -oc ../result/final_prediction/K562/inference_raw/MEME/RankLinear0.6_40_ZBED1/ -dna -nmotifs 5 -w 8 -maxsize 250000 -nostatus ../result/final_prediction/K562/fasta/RankLinear0.6_40/ZBED1.fasta model: mod= zoops nmotifs= 5 evt= inf objective function: em= E-value of product of p-values starts= E-value of product of p-values strands: + width: minw= 8 maxw= 8 nsites: minsites= 2 maxsites= 250 wnsites= 0.8 theta: spmap= uni spfuzz= 0.5 em: prior= dirichlet b= 0.01 maxiter= 50 distance= 1e-05 trim: wg= 11 ws= 1 endgaps= yes data: n= 20000 N= 250 sample: seed= 0 hsfrac= 0 searchsize= 20000 norand= no csites= 1000 Letter frequencies in dataset: A 0.227 C 0.278 G 0.278 T 0.216 Background letter frequencies (from file dataset with add-one prior applied): A 0.227 C 0.278 G 0.278 T 0.216 Background model order: 0 ******************************************************************************** ******************************************************************************** MOTIF TRTCGCGA MEME-1 width = 8 sites = 94 llr = 735 E-value = 2.8e-052 ******************************************************************************** -------------------------------------------------------------------------------- Motif TRTCGCGA MEME-1 Description -------------------------------------------------------------------------------- Simplified A 14::3:1a pos.-specific C :::a17:: probability G 16::619: matrix T 8:a::2:: bits 2.2 * * 2.0 * * 1.8 ** * 1.5 ** * Relative 1.3 ** ** Entropy 1.1 **** ** (11.3 bits) 0.9 **** *** 0.7 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel TGTCGCGA consensus A AT sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TRTCGCGA MEME-1 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr10:557081-557161 25 1.76e-05 CTGAACACAC TGTCGCGA TGCTGCTTGG chr4:154713484-154713564 51 1.76e-05 CTTGGGGACC TGTCGCGA CTTGTCGGGT chr3:42642314-42642394 42 1.76e-05 CCTCCTGCGC TGTCGCGA CGGGCCGGCG chr11:18127528-18127608 21 1.76e-05 TCCTCCTCCT TGTCGCGA CCCGGCGGCG chr21:35573876-35573956 43 1.76e-05 CCTGAATCAC TGTCGCGA TTGGGATCTG chr2:48010334-48010414 40 1.76e-05 GCTGTCGGTA TGTCGCGA CAGAGCACCC chr20:30467646-30467726 41 1.76e-05 AATCGCGTTA TGTCGCGA CCGAAGGTAG chr3:48956164-48956244 44 1.76e-05 GCCGGGAGCC TGTCGCGA CCCGAGCGAC chr22:19702364-19702444 66 1.76e-05 CACCCAGCCC TGTCGCGA TCACCGA chr16:68298321-68298401 59 1.76e-05 CGGCGCGCGC TGTCGCGA TCCGGCGGCG chr19:36630567-36630647 30 1.76e-05 AGGAGGTGTT TGTCGCGA CAACACCTGC chr5:149380486-149380566 26 1.76e-05 CGAGAGGGGC TGTCGCGA CTCCGCGCCG chr1:25943656-25943736 69 1.76e-05 gcccgggcgc tgtcgcga ccgg chr22:36424506-36424586 43 1.76e-05 CGGCCCCGAC TGTCGCGA CAGGCGGGcg chr7:2272559-2272639 13 3.19e-05 GGCGCCCATT TATCGCGA CACTTGCGCC chrX:53711120-53711200 34 3.19e-05 CGTTGAGAAC TATCGCGA TATTACGCTT chr8:74790254-74790334 4 3.19e-05 CCT TATCGCGA CCGCAAGGGT chr17:55631081-55631161 44 3.19e-05 GTCCTGTGTT TATCGCGA GAGAGCAGTG chr1:36023592-36023672 5 3.19e-05 GCCA TATCGCGA CACCATCGTG chr18:59854213-59854293 61 3.19e-05 CCGCTGCTGC TATCGCGA TAATTCTCGG chr4:187459257-187459337 35 3.19e-05 CTTTTCTGTT TATCGCGA TTATGTCTCT chr5:96038718-96038798 44 3.19e-05 CTTTTCCTAC TATCGCGA CCCTGGCGAT chr6:158958627-158958707 39 3.19e-05 GACAGGACCC TATCGCGA GTCGGTAGAa chr19:40029909-40029989 8 3.19e-05 ACTGTCT TATCGCGA TATACTCTTG chr16:77756447-77756527 34 4.63e-05 CCCAGGGCAA TGTCACGA CTTGGTCTTC chr22:39189836-39189916 34 4.63e-05 ATGGCAAACC TGTCACGA CAGAGCTCGC chr1:113162949-113163029 47 4.63e-05 GTGATTTTGC TGTCACGA CTCTTCGACA chr16:19343228-19343308 52 4.63e-05 cccccaccag tgtcacga cagttgacag chr11:27948566-27948646 9 4.63e-05 aacattta tgtcacga tatggcctca chr5:142571410-142571490 51 6.00e-05 TATGTGGAGC TGTCGTGA CAACACCAGA chr19:45972746-45972826 55 6.00e-05 AGGGGATCCC TGTCGTGA CAAGAGCGCC chr12:6641845-6641925 28 6.00e-05 GTGAGCTGGC TGTCGTGA CCACACTGGT chr1:6053849-6053929 38 6.00e-05 TCTTGCTTCC TGTCGTGA TAGGGACCTG chr13:61158772-61158852 46 6.00e-05 gcaattcccc tgtcgtga taaatcggct chr10:134479614-13447969 53 6.00e-05 CTTCCTCCCA TGTCGTGA CTGTTATAAT chr7:27824134-27824214 70 6.00e-05 AGACTTGATA TGTCGTGA CTA chr16:87032632-87032712 36 6.00e-05 gtcaccgtgc tgtcgtga ttctgtgttg chr2:23698908-23698988 17 7.17e-05 tcacgtgtgc tatcacga catggtttca chr3:182696418-182696498 73 7.17e-05 AACCAGAGAA TATCACGA chr12:112546650-11254673 15 7.17e-05 CTCGCTTGTC TATCACGA TAGTCGCGGT chr16:46865275-46865355 45 7.17e-05 TCGCCCAGAG TATCACGA GACGAGGGGA chr1:38731441-38731521 30 7.17e-05 tccccctaca tatcacga ggtgcatctt chr18:23669696-23669776 13 7.17e-05 CCTGTgtatt tatcacga cttacattaa chr1:46908583-46908663 45 8.29e-05 TGCCTGTCAC TATCGTGA CACTACAGGA chr12:124972188-12497226 47 8.29e-05 ctctctccct tatcgtga cagtcttgac chr21:47673532-47673612 21 9.40e-05 ccttcgctgt tgtcatga tagtgagctc chr19:53988890-53988970 9 9.40e-05 tacatgta tgtCATGA CATATATACA chr19:3737990-3738070 68 9.40e-05 TTGCTGTCCA TGTCATGA CCCGG chr2:169309455-169309535 21 9.40e-05 GGCTCtgaca tgtcatga catgtcatga chr3:4345267-4345347 30 1.12e-04 ACGGCCTCCC AGTCGCGA CCTTTTGTCT chrX:154255419-154255499 9 1.12e-04 CGCCCGCC AGTCGCGA CCGAGCTCCC chr4:100870649-100870729 53 1.12e-04 GGGCAGCCCA AGTCGCGA CACCGCATCA chr14:105267672-10526775 40 1.12e-04 GCCCGCGGGC AGTCGCGA CACGGTGCGG chr4:2366533-2366613 60 1.12e-04 GCCGCGGCAA AGTCGCGA GAGTACCGTG chr8:8194470-8194550 44 1.22e-04 CACAAACTAC TATCATGA TATGCCCTGG chr4:67206196-67206276 35 1.22e-04 atgtgtcata tatcatga tatatcacat chr1:154967211-154967291 21 1.22e-04 CCCTCAGGCT TATCATGA CACAGCCCTA chr6:52350813-52350893 64 1.37e-04 TCTGATAAAG AATCGCGA TCTAAGGAA chr1:184723497-184723577 22 1.37e-04 GAGCCGTTCC AATCGCGA CAGGAGAGGC chr12:131715801-13171588 37 1.37e-04 aaacgacagt aatcgcga cagagtggta chr17:76136849-76136929 35 1.51e-04 AAGCAGCGCC TGTCGCAA CTCGCCACTT chr1:228327765-228327845 47 1.74e-04 ACGCCCCTGC GGTCGCGA CAGGCCAGCG chr19:40931849-40931929 32 1.74e-04 CCCGCGCCTG GGTCGCGA GACGCAGTTC chr4:7599120-7599200 72 2.03e-04 GGAAGAGGAC TATCGCAA T chr19:48996360-48996440 55 2.03e-04 ATCCAGACTC TGTCCCGA TCCTAGGCGC chr3:72924737-72924817 43 2.03e-04 agagcgagac tatcgcaa aagaaaaaaa chr11:76838515-76838595 29 2.03e-04 GAAACTGTCA TGTCCCGA TAGGGCCGCG chr2:152617051-152617131 35 2.03e-04 ccagcctcac tatcgcaa caggcctcaa chr7:151624774-151624854 70 2.03e-04 TCCCTGGAAC TGTCCCGA CAT chr17:74637884-74637964 52 2.03e-04 tggacctgta tgtcccga catggaaaga chr17:2527840-2527920 49 2.03e-04 tgagacttac tatcgcaa caatagcaca chr19:18896798-18896878 19 2.03e-04 AGGCGGCAGT TGTCCCGA CTGTCAGGGA chr2:182757346-182757426 15 2.39e-04 CCAACGAGAA GATCGCGA TATGGCTCAA chr6:26123956-26124036 20 2.39e-04 GAGATGCCAG TGTCGGGA TGGACCTGTT chr4:6927318-6927398 4 2.39e-04 TTT TGTCGGGA AACTTTCTTC chr2:9893585-9893665 48 2.39e-04 TGCTGCTGAG GATCGCGA TAAGGACCAA chr7:149119424-149119504 48 2.39e-04 GGGGCTCGGA TGTCGGGA CTAGCGGGTC chr19:46438646-46438726 16 2.39e-04 AGTGCAAACG GATCGCGA TAGCAGGGCT chr21:47745319-47745399 51 2.69e-04 GTCTGTGCTA TATCCCGA CATGGATAGG chr6:16215632-16215712 28 2.97e-04 catcccgtcc agtcgtga caaccgcaaa chr6:14864260-14864340 50 2.97e-04 gcttggtggt tatcggga taGGACTGTA chr9:119233504-119233584 43 2.97e-04 AGTTGGATCC AGTCGTGA GAGTCAGATA chr19:11201253-11201333 52 3.33e-04 CCGCGGTTCC TGTCACAA AGGCGACGAC chr19:10974204-10974284 52 3.33e-04 TGACAATCTG TGTCACAA TCTGTGACAG chr16:4357900-4357980 11 3.63e-04 GTTTCCACTT GGTCACGA CTCAAAAATG chr7:151000918-151000998 44 3.63e-04 GTGGATGACA GGTCACGA CTTGACGATG chr19:11200156-11200236 25 3.90e-04 GGACACAGCA GGTCGTGA TCCGGGTCGG chr1:148604882-148604962 55 3.90e-04 agtcccctac tatcacaa gttatgcagt chr13:41976858-41976938 45 4.91e-04 GCAGTGCTCA TATCAGGA CATGCTGTTG chr10:11911279-11911359 17 5.39e-04 ATCAGCGTGA GGTCATGA GCATGACATA chr19:18451418-18451498 32 5.39e-04 CTGTCGCGCC AGTCGCAA CAGAAGCAGG chr6:26158528-26158608 52 5.89e-04 AGGCAATGGG GATCATGA ATTCCTTCGT chr11:71098941-71099021 59 5.89e-04 acatcctgac agtcccga cattctgaca chr4:57396768-57396848 30 6.08e-04 CTGGGCAACC AGTCGGGA GGGTGAGTCC -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TRTCGCGA MEME-1 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr10:557081-557161 1.8e-05 24_[+1]_48 chr4:154713484-154713564 1.8e-05 50_[+1]_22 chr3:42642314-42642394 1.8e-05 41_[+1]_31 chr11:18127528-18127608 1.8e-05 20_[+1]_52 chr21:35573876-35573956 1.8e-05 42_[+1]_30 chr2:48010334-48010414 1.8e-05 39_[+1]_33 chr20:30467646-30467726 1.8e-05 40_[+1]_32 chr3:48956164-48956244 1.8e-05 43_[+1]_29 chr22:19702364-19702444 1.8e-05 65_[+1]_7 chr16:68298321-68298401 1.8e-05 58_[+1]_14 chr19:36630567-36630647 1.8e-05 29_[+1]_43 chr5:149380486-149380566 1.8e-05 25_[+1]_47 chr1:25943656-25943736 1.8e-05 68_[+1]_4 chr22:36424506-36424586 1.8e-05 42_[+1]_30 chr7:2272559-2272639 3.2e-05 12_[+1]_60 chrX:53711120-53711200 3.2e-05 33_[+1]_39 chr8:74790254-74790334 3.2e-05 3_[+1]_69 chr17:55631081-55631161 3.2e-05 43_[+1]_29 chr1:36023592-36023672 3.2e-05 4_[+1]_68 chr18:59854213-59854293 3.2e-05 60_[+1]_12 chr4:187459257-187459337 3.2e-05 34_[+1]_38 chr5:96038718-96038798 3.2e-05 43_[+1]_29 chr6:158958627-158958707 3.2e-05 38_[+1]_34 chr19:40029909-40029989 3.2e-05 7_[+1]_65 chr16:77756447-77756527 4.6e-05 33_[+1]_39 chr22:39189836-39189916 4.6e-05 33_[+1]_39 chr1:113162949-113163029 4.6e-05 46_[+1]_26 chr16:19343228-19343308 4.6e-05 51_[+1]_21 chr11:27948566-27948646 4.6e-05 8_[+1]_64 chr5:142571410-142571490 6e-05 50_[+1]_22 chr19:45972746-45972826 6e-05 54_[+1]_18 chr12:6641845-6641925 6e-05 27_[+1]_45 chr1:6053849-6053929 6e-05 37_[+1]_35 chr13:61158772-61158852 6e-05 45_[+1]_27 chr10:134479614-13447969 6e-05 52_[+1]_20 chr7:27824134-27824214 6e-05 69_[+1]_3 chr16:87032632-87032712 6e-05 35_[+1]_37 chr2:23698908-23698988 7.2e-05 16_[+1]_56 chr3:182696418-182696498 7.2e-05 72_[+1] chr12:112546650-11254673 7.2e-05 14_[+1]_58 chr16:46865275-46865355 7.2e-05 44_[+1]_28 chr1:38731441-38731521 7.2e-05 29_[+1]_43 chr18:23669696-23669776 7.2e-05 12_[+1]_60 chr1:46908583-46908663 8.3e-05 44_[+1]_28 chr12:124972188-12497226 8.3e-05 46_[+1]_26 chr21:47673532-47673612 9.4e-05 20_[+1]_52 chr19:53988890-53988970 9.4e-05 8_[+1]_64 chr19:3737990-3738070 9.4e-05 67_[+1]_5 chr2:169309455-169309535 9.4e-05 20_[+1]_52 chr3:4345267-4345347 0.00011 29_[+1]_43 chrX:154255419-154255499 0.00011 8_[+1]_64 chr4:100870649-100870729 0.00011 52_[+1]_20 chr14:105267672-10526775 0.00011 39_[+1]_33 chr4:2366533-2366613 0.00011 59_[+1]_13 chr8:8194470-8194550 0.00012 43_[+1]_29 chr4:67206196-67206276 0.00012 34_[+1]_38 chr1:154967211-154967291 0.00012 20_[+1]_52 chr6:52350813-52350893 0.00014 63_[+1]_9 chr1:184723497-184723577 0.00014 21_[+1]_51 chr12:131715801-13171588 0.00014 36_[+1]_36 chr17:76136849-76136929 0.00015 34_[+1]_38 chr1:228327765-228327845 0.00017 46_[+1]_26 chr19:40931849-40931929 0.00017 31_[+1]_41 chr4:7599120-7599200 0.0002 71_[+1]_1 chr19:48996360-48996440 0.0002 54_[+1]_18 chr3:72924737-72924817 0.0002 42_[+1]_30 chr11:76838515-76838595 0.0002 28_[+1]_44 chr2:152617051-152617131 0.0002 34_[+1]_38 chr7:151624774-151624854 0.0002 69_[+1]_3 chr17:74637884-74637964 0.0002 51_[+1]_21 chr17:2527840-2527920 0.0002 48_[+1]_24 chr19:18896798-18896878 0.0002 18_[+1]_54 chr2:182757346-182757426 0.00024 14_[+1]_58 chr6:26123956-26124036 0.00024 19_[+1]_53 chr4:6927318-6927398 0.00024 3_[+1]_69 chr2:9893585-9893665 0.00024 47_[+1]_25 chr7:149119424-149119504 0.00024 47_[+1]_25 chr19:46438646-46438726 0.00024 15_[+1]_57 chr21:47745319-47745399 0.00027 50_[+1]_22 chr6:16215632-16215712 0.0003 27_[+1]_45 chr6:14864260-14864340 0.0003 49_[+1]_23 chr9:119233504-119233584 0.0003 42_[+1]_30 chr19:11201253-11201333 0.00033 51_[+1]_21 chr19:10974204-10974284 0.00033 51_[+1]_21 chr16:4357900-4357980 0.00036 10_[+1]_62 chr7:151000918-151000998 0.00036 43_[+1]_29 chr19:11200156-11200236 0.00039 24_[+1]_48 chr1:148604882-148604962 0.00039 54_[+1]_18 chr13:41976858-41976938 0.00049 44_[+1]_28 chr10:11911279-11911359 0.00054 16_[+1]_56 chr19:18451418-18451498 0.00054 31_[+1]_41 chr6:26158528-26158608 0.00059 51_[+1]_21 chr11:71098941-71099021 0.00059 58_[+1]_14 chr4:57396768-57396848 0.00061 29_[+1]_43 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TRTCGCGA MEME-1 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF TRTCGCGA width=8 seqs=94 chr10:557081-557161 ( 25) TGTCGCGA 1 chr4:154713484-154713564 ( 51) TGTCGCGA 1 chr3:42642314-42642394 ( 42) TGTCGCGA 1 chr11:18127528-18127608 ( 21) TGTCGCGA 1 chr21:35573876-35573956 ( 43) TGTCGCGA 1 chr2:48010334-48010414 ( 40) TGTCGCGA 1 chr20:30467646-30467726 ( 41) TGTCGCGA 1 chr3:48956164-48956244 ( 44) TGTCGCGA 1 chr22:19702364-19702444 ( 66) TGTCGCGA 1 chr16:68298321-68298401 ( 59) TGTCGCGA 1 chr19:36630567-36630647 ( 30) TGTCGCGA 1 chr5:149380486-149380566 ( 26) TGTCGCGA 1 chr1:25943656-25943736 ( 69) TGTCGCGA 1 chr22:36424506-36424586 ( 43) TGTCGCGA 1 chr7:2272559-2272639 ( 13) TATCGCGA 1 chrX:53711120-53711200 ( 34) TATCGCGA 1 chr8:74790254-74790334 ( 4) TATCGCGA 1 chr17:55631081-55631161 ( 44) TATCGCGA 1 chr1:36023592-36023672 ( 5) TATCGCGA 1 chr18:59854213-59854293 ( 61) TATCGCGA 1 chr4:187459257-187459337 ( 35) TATCGCGA 1 chr5:96038718-96038798 ( 44) TATCGCGA 1 chr6:158958627-158958707 ( 39) TATCGCGA 1 chr19:40029909-40029989 ( 8) TATCGCGA 1 chr16:77756447-77756527 ( 34) TGTCACGA 1 chr22:39189836-39189916 ( 34) TGTCACGA 1 chr1:113162949-113163029 ( 47) TGTCACGA 1 chr16:19343228-19343308 ( 52) TGTCACGA 1 chr11:27948566-27948646 ( 9) TGTCACGA 1 chr5:142571410-142571490 ( 51) TGTCGTGA 1 chr19:45972746-45972826 ( 55) TGTCGTGA 1 chr12:6641845-6641925 ( 28) TGTCGTGA 1 chr1:6053849-6053929 ( 38) TGTCGTGA 1 chr13:61158772-61158852 ( 46) TGTCGTGA 1 chr10:134479614-13447969 ( 53) TGTCGTGA 1 chr7:27824134-27824214 ( 70) TGTCGTGA 1 chr16:87032632-87032712 ( 36) TGTCGTGA 1 chr2:23698908-23698988 ( 17) TATCACGA 1 chr3:182696418-182696498 ( 73) TATCACGA 1 chr12:112546650-11254673 ( 15) TATCACGA 1 chr16:46865275-46865355 ( 45) TATCACGA 1 chr1:38731441-38731521 ( 30) TATCACGA 1 chr18:23669696-23669776 ( 13) TATCACGA 1 chr1:46908583-46908663 ( 45) TATCGTGA 1 chr12:124972188-12497226 ( 47) TATCGTGA 1 chr21:47673532-47673612 ( 21) TGTCATGA 1 chr19:53988890-53988970 ( 9) TGTCATGA 1 chr19:3737990-3738070 ( 68) TGTCATGA 1 chr2:169309455-169309535 ( 21) TGTCATGA 1 chr3:4345267-4345347 ( 30) AGTCGCGA 1 chrX:154255419-154255499 ( 9) AGTCGCGA 1 chr4:100870649-100870729 ( 53) AGTCGCGA 1 chr14:105267672-10526775 ( 40) AGTCGCGA 1 chr4:2366533-2366613 ( 60) AGTCGCGA 1 chr8:8194470-8194550 ( 44) TATCATGA 1 chr4:67206196-67206276 ( 35) TATCATGA 1 chr1:154967211-154967291 ( 21) TATCATGA 1 chr6:52350813-52350893 ( 64) AATCGCGA 1 chr1:184723497-184723577 ( 22) AATCGCGA 1 chr12:131715801-13171588 ( 37) AATCGCGA 1 chr17:76136849-76136929 ( 35) TGTCGCAA 1 chr1:228327765-228327845 ( 47) GGTCGCGA 1 chr19:40931849-40931929 ( 32) GGTCGCGA 1 chr4:7599120-7599200 ( 72) TATCGCAA 1 chr19:48996360-48996440 ( 55) TGTCCCGA 1 chr3:72924737-72924817 ( 43) TATCGCAA 1 chr11:76838515-76838595 ( 29) TGTCCCGA 1 chr2:152617051-152617131 ( 35) TATCGCAA 1 chr7:151624774-151624854 ( 70) TGTCCCGA 1 chr17:74637884-74637964 ( 52) TGTCCCGA 1 chr17:2527840-2527920 ( 49) TATCGCAA 1 chr19:18896798-18896878 ( 19) TGTCCCGA 1 chr2:182757346-182757426 ( 15) GATCGCGA 1 chr6:26123956-26124036 ( 20) TGTCGGGA 1 chr4:6927318-6927398 ( 4) TGTCGGGA 1 chr2:9893585-9893665 ( 48) GATCGCGA 1 chr7:149119424-149119504 ( 48) TGTCGGGA 1 chr19:46438646-46438726 ( 16) GATCGCGA 1 chr21:47745319-47745399 ( 51) TATCCCGA 1 chr6:16215632-16215712 ( 28) AGTCGTGA 1 chr6:14864260-14864340 ( 50) TATCGGGA 1 chr9:119233504-119233584 ( 43) AGTCGTGA 1 chr19:11201253-11201333 ( 52) TGTCACAA 1 chr19:10974204-10974284 ( 52) TGTCACAA 1 chr16:4357900-4357980 ( 11) GGTCACGA 1 chr7:151000918-151000998 ( 44) GGTCACGA 1 chr19:11200156-11200236 ( 25) GGTCGTGA 1 chr1:148604882-148604962 ( 55) TATCACAA 1 chr13:41976858-41976938 ( 45) TATCAGGA 1 chr10:11911279-11911359 ( 17) GGTCATGA 1 chr19:18451418-18451498 ( 32) AGTCGCAA 1 chr6:26158528-26158608 ( 52) GATCATGA 1 chr11:71098941-71099021 ( 59) AGTCCCGA 1 chr4:57396768-57396848 ( 30) AGTCGGGA 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TRTCGCGA MEME-1 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 9.49826 E= 2.8e-052 -72 -1320 -139 180 75 -1320 115 -1320 -1320 -1320 -1320 221 -1320 185 -1320 -1320 28 -190 122 -1320 -1320 134 -212 11 -125 -1320 170 -1320 214 -1320 -1320 -1320 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TRTCGCGA MEME-1 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 94 E= 2.8e-052 0.138298 0.000000 0.106383 0.755319 0.382979 0.000000 0.617021 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 0.276596 0.074468 0.648936 0.000000 0.000000 0.702128 0.063830 0.234043 0.095745 0.000000 0.904255 0.000000 1.000000 0.000000 0.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TRTCGCGA MEME-1 regular expression -------------------------------------------------------------------------------- T[GA]TC[GA][CT]GA -------------------------------------------------------------------------------- Time 4.76 secs. ******************************************************************************** ******************************************************************************** MOTIF TCACTGCA MEME-2 width = 8 sites = 9 llr = 92 E-value = 1.2e+004 ******************************************************************************** -------------------------------------------------------------------------------- Motif TCACTGCA MEME-2 Description -------------------------------------------------------------------------------- Simplified A ::a:2::9 pos.-specific C :a:a::a: probability G :::::a:: matrix T a:::8::1 bits 2.2 * * 2.0 * * 1.8 **** ** 1.5 **** *** Relative 1.3 ******** Entropy 1.1 ******** (14.8 bits) 0.9 ******** 0.7 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel TCACTGCA consensus A sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCACTGCA MEME-2 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr6:37143778-37143858 52 1.44e-05 cgatctcggc tcactgca actttcactt chr14:102545511-10254559 39 1.44e-05 cgcaatcagc tcactgca acctacgcct chr3:151986705-151986785 20 1.44e-05 AACAGTCTTT TCACTGCA GCTGAATGAG chr11:117997321-11799740 35 1.44e-05 GAGGCATGTG TCACTGCA GCAAACAGGC chr21:35573876-35573956 67 1.44e-05 TCTGTGAAAG TCACTGCA GAAAGA chr1:145443016-145443096 16 1.44e-05 tgatcttagc tcactgca gccttgattt chr17:76136849-76136929 60 2.95e-05 CTTGTTCTCC TCACAGCA GGTTCAGGAG chr16:57716832-57716912 20 2.95e-05 GGCCTGAAGT TCACAGCA TGGGAAAGAC chr16:19343228-19343308 31 4.31e-05 ctggtcatcc tcactgct acacccccac -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCACTGCA MEME-2 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr6:37143778-37143858 1.4e-05 51_[+2]_21 chr14:102545511-10254559 1.4e-05 38_[+2]_34 chr3:151986705-151986785 1.4e-05 19_[+2]_53 chr11:117997321-11799740 1.4e-05 34_[+2]_38 chr21:35573876-35573956 1.4e-05 66_[+2]_6 chr1:145443016-145443096 1.4e-05 15_[+2]_57 chr17:76136849-76136929 2.9e-05 59_[+2]_13 chr16:57716832-57716912 2.9e-05 19_[+2]_53 chr16:19343228-19343308 4.3e-05 30_[+2]_42 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCACTGCA MEME-2 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF TCACTGCA width=8 seqs=9 chr6:37143778-37143858 ( 52) TCACTGCA 1 chr14:102545511-10254559 ( 39) TCACTGCA 1 chr3:151986705-151986785 ( 20) TCACTGCA 1 chr11:117997321-11799740 ( 35) TCACTGCA 1 chr21:35573876-35573956 ( 67) TCACTGCA 1 chr1:145443016-145443096 ( 16) TCACTGCA 1 chr17:76136849-76136929 ( 60) TCACAGCA 1 chr16:57716832-57716912 ( 20) TCACAGCA 1 chr16:19343228-19343308 ( 31) TCACTGCT 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCACTGCA MEME-2 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 11.1193 E= 1.2e+004 -982 -982 -982 221 -982 184 -982 -982 214 -982 -982 -982 -982 184 -982 -982 -3 -982 -982 184 -982 -982 184 -982 -982 184 -982 -982 197 -982 -982 -96 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCACTGCA MEME-2 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 9 E= 1.2e+004 0.000000 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.222222 0.000000 0.000000 0.777778 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.888889 0.000000 0.000000 0.111111 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCACTGCA MEME-2 regular expression -------------------------------------------------------------------------------- TCAC[TA]GCA -------------------------------------------------------------------------------- Time 8.32 secs. ******************************************************************************** ******************************************************************************** MOTIF YCAYGAYA MEME-3 width = 8 sites = 35 llr = 281 E-value = 4.7e+003 ******************************************************************************** -------------------------------------------------------------------------------- Motif YCAYGAYA MEME-3 Description -------------------------------------------------------------------------------- Simplified A :28::a:a pos.-specific C 68:4::6: probability G ::2:a::: matrix T 4::6::4: bits 2.2 * * 2.0 * * 1.8 ** * 1.5 ** * Relative 1.3 * ** * Entropy 1.1 ******* (11.6 bits) 0.9 ******** 0.7 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel CCATGACA consensus TAGC T sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YCAYGAYA MEME-3 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr3:151986705-151986785 58 1.51e-05 CACAATGCTC CCATGACA AGGAGCTGAC chr1:247634513-247634593 41 1.51e-05 CGGAGCTCCA CCATGACA CAGCTGGAGA chr1:247634288-247634368 58 1.51e-05 CAGAGCTCCA CCATGACA CAGCTGGAGA chr8:143645584-143645664 49 2.68e-05 CAGGAGAAGC CCATGATA CACAGGAGAA chr17:74637884-74637964 73 2.68e-05 ggaaagatgt ccatgata chr10:71667306-71667386 60 2.68e-05 taacccactt ccatgata actaacccac chr22:46964086-46964166 41 2.68e-05 TAACCCACAC CCATGATA ACTAGGCCTC chr8:143645385-143645465 48 2.68e-05 CAGGAGAAGC CCATGATA CGCAGGAGAA chr12:6641845-6641925 56 3.85e-05 GCCTCTGCTG TCATGACA ACAGCACACT chr2:169309455-169309535 33 3.85e-05 tcatgacatg tcatgaca tgacTTTCGG chr4:67206196-67206276 9 4.77e-05 gtcatata tcatgata tatcacgtat chr6:14118108-14118188 16 6.71e-05 CCCCGCCCCT CCACGACA CCCCCTCCCG chr8:143644476-143644556 22 6.71e-05 CAGGAGAAGC CCACGACA TGCAGAAGCC chr15:66923217-66923297 5 9.73e-05 CCTC TCACGACA GTGGTTGCCT chr9:14525975-14526055 26 9.73e-05 tcattcatcc tcacgaca ggttggagcg chr6:170407383-170407463 14 9.73e-05 accacacagc tcacgaca acaccacaca chr18:23669696-23669776 35 9.73e-05 cattaactgg tcacgaca gtctccacca chr13:42570250-42570330 13 1.09e-04 ATGGCCAGCC TCACGATA ATGTTGGAGA chr3:58984368-58984448 73 1.09e-04 GAAACTCTCA TCACGATA chr16:998202-998282 25 1.21e-04 gagtcagaga caatgaca gagTTACAGA chr1:184723497-184723577 58 1.21e-04 GACCGGGTCG CAATGACA GGCACCCCTC chr16:1000881-1000961 57 1.21e-04 cagagtcagc caatgaca gagtcagagc chr16:1001167-1001247 41 1.21e-04 CAGAGTCAGC CAATGACA GAGTCAGCTG chr2:97202931-97203011 63 1.40e-04 CCCCTCCGCC CCGTGACA TCCCGCAGGT chr15:73669892-73669972 58 1.73e-04 gcgacagagg ccgtgata gaggctgtga chr16:75600822-75600902 36 1.73e-04 CGTCTGGGAC CCGTGATA GGCCCCAGGC chr6:170407594-170407674 24 1.88e-04 accacatagc tcgtgaca gcaccaaaca chr11:62618998-62619078 1 1.88e-04 . tcgtgaca ggtatctgca chr6:26158528-26158608 70 2.22e-04 ATTCCTTCGT CAACGACA TCT chr22:36424506-36424586 5 2.46e-04 CGAC CCGCGACA GGCCACCTCC chr5:10262628-10262708 24 2.89e-04 GGAACCTCAT CCGCGATA ATCGTGTGGT chr4:2366533-2366613 21 2.89e-04 GGGCTGTGTT CCGCGATA CCGCGATAAA chr10:74036381-74036461 45 3.17e-04 AGGCCTACCT TAACGATA CCTTGGGTCA chr1:14762202-14762282 45 3.17e-04 tgacagggcc taACGATA TCTTCGAATG chr10:11911279-11911359 25 3.94e-04 GAGGTCATGA GCATGACA TACCACCTTC -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YCAYGAYA MEME-3 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr3:151986705-151986785 1.5e-05 57_[+3]_15 chr1:247634513-247634593 1.5e-05 40_[+3]_32 chr1:247634288-247634368 1.5e-05 57_[+3]_15 chr8:143645584-143645664 2.7e-05 48_[+3]_24 chr17:74637884-74637964 2.7e-05 72_[+3] chr10:71667306-71667386 2.7e-05 59_[+3]_13 chr22:46964086-46964166 2.7e-05 40_[+3]_32 chr8:143645385-143645465 2.7e-05 47_[+3]_25 chr12:6641845-6641925 3.9e-05 55_[+3]_17 chr2:169309455-169309535 3.9e-05 32_[+3]_40 chr4:67206196-67206276 4.8e-05 8_[+3]_64 chr6:14118108-14118188 6.7e-05 15_[+3]_57 chr8:143644476-143644556 6.7e-05 21_[+3]_51 chr15:66923217-66923297 9.7e-05 4_[+3]_68 chr9:14525975-14526055 9.7e-05 25_[+3]_47 chr6:170407383-170407463 9.7e-05 13_[+3]_59 chr18:23669696-23669776 9.7e-05 34_[+3]_38 chr13:42570250-42570330 0.00011 12_[+3]_60 chr3:58984368-58984448 0.00011 72_[+3] chr16:998202-998282 0.00012 24_[+3]_48 chr1:184723497-184723577 0.00012 57_[+3]_15 chr16:1000881-1000961 0.00012 56_[+3]_16 chr16:1001167-1001247 0.00012 40_[+3]_32 chr2:97202931-97203011 0.00014 62_[+3]_10 chr15:73669892-73669972 0.00017 57_[+3]_15 chr16:75600822-75600902 0.00017 35_[+3]_37 chr6:170407594-170407674 0.00019 23_[+3]_49 chr11:62618998-62619078 0.00019 [+3]_72 chr6:26158528-26158608 0.00022 69_[+3]_3 chr22:36424506-36424586 0.00025 4_[+3]_68 chr5:10262628-10262708 0.00029 23_[+3]_49 chr4:2366533-2366613 0.00029 20_[+3]_52 chr10:74036381-74036461 0.00032 44_[+3]_28 chr1:14762202-14762282 0.00032 44_[+3]_28 chr10:11911279-11911359 0.00039 24_[+3]_48 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YCAYGAYA MEME-3 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF YCAYGAYA width=8 seqs=35 chr3:151986705-151986785 ( 58) CCATGACA 1 chr1:247634513-247634593 ( 41) CCATGACA 1 chr1:247634288-247634368 ( 58) CCATGACA 1 chr8:143645584-143645664 ( 49) CCATGATA 1 chr17:74637884-74637964 ( 73) CCATGATA 1 chr10:71667306-71667386 ( 60) CCATGATA 1 chr22:46964086-46964166 ( 41) CCATGATA 1 chr8:143645385-143645465 ( 48) CCATGATA 1 chr12:6641845-6641925 ( 56) TCATGACA 1 chr2:169309455-169309535 ( 33) TCATGACA 1 chr4:67206196-67206276 ( 9) TCATGATA 1 chr6:14118108-14118188 ( 16) CCACGACA 1 chr8:143644476-143644556 ( 22) CCACGACA 1 chr15:66923217-66923297 ( 5) TCACGACA 1 chr9:14525975-14526055 ( 26) TCACGACA 1 chr6:170407383-170407463 ( 14) TCACGACA 1 chr18:23669696-23669776 ( 35) TCACGACA 1 chr13:42570250-42570330 ( 13) TCACGATA 1 chr3:58984368-58984448 ( 73) TCACGATA 1 chr16:998202-998282 ( 25) CAATGACA 1 chr1:184723497-184723577 ( 58) CAATGACA 1 chr16:1000881-1000961 ( 57) CAATGACA 1 chr16:1001167-1001247 ( 41) CAATGACA 1 chr2:97202931-97203011 ( 63) CCGTGACA 1 chr15:73669892-73669972 ( 58) CCGTGATA 1 chr16:75600822-75600902 ( 36) CCGTGATA 1 chr6:170407594-170407674 ( 24) TCGTGACA 1 chr11:62618998-62619078 ( 1) TCGTGACA 1 chr6:26158528-26158608 ( 70) CAACGACA 1 chr22:36424506-36424586 ( 5) CCGCGACA 1 chr5:10262628-10262708 ( 24) CCGCGATA 1 chr4:2366533-2366613 ( 21) CCGCGATA 1 chr10:74036381-74036461 ( 45) TAACGATA 1 chr1:14762202-14762282 ( 45) TAACGATA 1 chr10:11911279-11911359 ( 25) GCATGACA 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YCAYGAYA MEME-3 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 10.4104 E= 4.7e+003 -1177 111 -328 78 -18 152 -1177 -1177 176 -1177 -28 -1177 -1177 52 -1177 147 -1177 -1177 185 -1177 214 -1177 -1177 -1177 -1177 111 -1177 89 214 -1177 -1177 -1177 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YCAYGAYA MEME-3 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 35 E= 4.7e+003 0.000000 0.600000 0.028571 0.371429 0.200000 0.800000 0.000000 0.000000 0.771429 0.000000 0.228571 0.000000 0.000000 0.400000 0.000000 0.600000 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.600000 0.000000 0.400000 1.000000 0.000000 0.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YCAYGAYA MEME-3 regular expression -------------------------------------------------------------------------------- [CT][CA][AG][TC]GA[CT]A -------------------------------------------------------------------------------- Time 11.87 secs. ******************************************************************************** ******************************************************************************** MOTIF TTTGTYTT MEME-4 width = 8 sites = 2 llr = 22 E-value = 1.1e+005 ******************************************************************************** -------------------------------------------------------------------------------- Motif TTTGTYTT MEME-4 Description -------------------------------------------------------------------------------- Simplified A :::::::: pos.-specific C :::::5:: probability G :::a:::: matrix T aaa:a5aa bits 2.2 *** * ** 2.0 *** * ** 1.8 ***** ** 1.5 ***** ** Relative 1.3 ***** ** Entropy 1.1 ******** (16.1 bits) 0.9 ******** 0.7 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel TTTGTCTT consensus T sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTTGTYTT MEME-4 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr12:104342714-10434279 20 6.10e-06 aatattgggt tttgtttt gagacggtgt chr3:4345267-4345347 41 1.39e-05 GTCGCGACCT TTTGTCTT CTCTTACAGC -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTTGTYTT MEME-4 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr12:104342714-10434279 6.1e-06 19_[+4]_53 chr3:4345267-4345347 1.4e-05 40_[+4]_32 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTTGTYTT MEME-4 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF TTTGTYTT width=8 seqs=2 chr12:104342714-10434279 ( 20) TTTGTTTT 1 chr3:4345267-4345347 ( 41) TTTGTCTT 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTTGTYTT MEME-4 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 13.1555 E= 1.1e+005 -765 -765 -765 220 -765 -765 -765 220 -765 -765 -765 220 -765 -765 184 -765 -765 -765 -765 220 -765 84 -765 120 -765 -765 -765 220 -765 -765 -765 220 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTTGTYTT MEME-4 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 2 E= 1.1e+005 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.500000 0.000000 0.500000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTTGTYTT MEME-4 regular expression -------------------------------------------------------------------------------- TTTGT[CT]TT -------------------------------------------------------------------------------- Time 15.35 secs. ******************************************************************************** ******************************************************************************** MOTIF TCTTTATT MEME-5 width = 8 sites = 2 llr = 24 E-value = 3.2e+004 ******************************************************************************** -------------------------------------------------------------------------------- Motif TCTTTATT MEME-5 Description -------------------------------------------------------------------------------- Simplified A :::::a:: pos.-specific C :a:::::: probability G :::::::: matrix T a:aaa:aa bits 2.2 * ****** 2.0 * ****** 1.8 ******** 1.5 ******** Relative 1.3 ******** Entropy 1.1 ******** (17.2 bits) 0.9 ******** 0.7 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel TCTTTATT consensus sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCTTTATT MEME-5 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr2:30884200-30884280 22 6.41e-06 CTGGGTAACT TCTTTATT GTGCAGCAAG chr15:45019333-45019413 73 6.41e-06 TTCCAGTGGT TCTTTATT -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCTTTATT MEME-5 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr2:30884200-30884280 6.4e-06 21_[+5]_51 chr15:45019333-45019413 6.4e-06 72_[+5] -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCTTTATT MEME-5 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF TCTTTATT width=8 seqs=2 chr2:30884200-30884280 ( 22) TCTTTATT 1 chr15:45019333-45019413 ( 73) TCTTTATT 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCTTTATT MEME-5 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 13.1555 E= 3.2e+004 -765 -765 -765 220 -765 184 -765 -765 -765 -765 -765 220 -765 -765 -765 220 -765 -765 -765 220 213 -765 -765 -765 -765 -765 -765 220 -765 -765 -765 220 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCTTTATT MEME-5 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 2 E= 3.2e+004 0.000000 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCTTTATT MEME-5 regular expression -------------------------------------------------------------------------------- TCTTTATT -------------------------------------------------------------------------------- Time 18.82 secs. ******************************************************************************** ******************************************************************************** SUMMARY OF MOTIFS ******************************************************************************** -------------------------------------------------------------------------------- Combined block diagrams: non-overlapping sites with p-value < 0.0001 -------------------------------------------------------------------------------- SEQUENCE NAME COMBINED P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr22:36424506-36424586 1.54e-02 42_[+1(1.76e-05)]_30 chr2:169309455-169309535 8.84e-03 22_[+3(3.85e-05)]_2_[+3(3.85e-05)]_\ 40 chr19:46438646-46438726 1.89e-02 80 chr16:87032632-87032712 9.51e-04 15_[+1(6.00e-05)]_12_[+1(6.00e-05)]_\ 8_[+1(9.40e-05)]_21 chr19:40029909-40029989 6.90e-04 7_[+1(3.19e-05)]_65 chr1:25943656-25943736 6.60e-02 68_[+1(1.76e-05)]_4 chr8:143645385-143645465 2.24e-01 27_[+3(8.22e-05)]_12_[+3(2.68e-05)]_\ 25 chr11:71098941-71099021 1.74e-01 80 chr11:27948566-27948646 4.19e-04 8_[+1(4.63e-05)]_64 chr19:54641705-54641785 8.22e-01 80 chr2:122494677-122494757 5.10e-01 80 chr19:18896798-18896878 2.01e-01 80 chr10:105154074-10515415 1.32e-01 80 chr21:47745319-47745399 9.53e-02 80 chr16:19343228-19343308 2.05e-04 30_[+2(4.31e-05)]_13_[+1(4.63e-05)]_\ 21 chr5:1193265-1193345 6.04e-01 80 chr7:27824134-27824214 7.57e-02 69_[+1(6.00e-05)]_3 chr6:158958627-158958707 9.17e-02 38_[+1(3.19e-05)]_34 chr18:23669696-23669776 6.89e-05 12_[+1(7.17e-05)]_14_[+3(9.73e-05)]_\ 38 chr16:1001167-1001247 4.69e-01 80 chr1:153895967-153896047 5.92e-01 80 chr1:180823717-180823797 2.03e-01 80 chr19:10974204-10974284 1.75e-01 80 chr4:2366533-2366613 2.46e-02 80 chr1:38731441-38731521 1.52e-01 29_[+1(7.17e-05)]_43 chr19:3737990-3738070 3.53e-03 20_[+1(9.40e-05)]_39_[+1(9.40e-05)]_\ 5 chr14:105267672-10526775 2.02e-02 80 chr13:41976858-41976938 7.33e-02 80 chr17:2527840-2527920 9.53e-02 80 chr16:75600822-75600902 1.50e-01 80 chr22:46964086-46964166 5.57e-02 [+3(4.77e-05)]_32_[+3(2.68e-05)]_12_\ [+3(4.77e-05)]_12 chr4:57396768-57396848 2.29e-01 80 chr11:134435422-13443550 8.19e-01 80 chr5:96038718-96038798 6.67e-02 43_[+1(3.19e-05)]_29 chr6:3157139-3157219 7.91e-02 80 chr12:124972188-12497226 5.35e-03 46_[+1(8.29e-05)]_26 chr16:1000881-1000961 2.67e-01 80 chr19:14625404-14625484 8.96e-01 80 chr19:53988890-53988970 6.37e-04 10_[+3(3.85e-05)]_62 chr1:247634288-247634368 3.48e-02 5_[+3(1.51e-05)]_44_[+3(1.51e-05)]_\ 15 chr10:134479614-13447969 1.92e-02 52_[+1(6.00e-05)]_20 chr6:7675690-7675770 6.27e-04 3_[+4(1.39e-05)]_69 chr12:131715801-13171588 1.24e-03 80 chr19:18451418-18451498 3.60e-01 80 chr6:31786053-31786133 8.80e-01 80 chr1:184723497-184723577 3.55e-02 80 chr15:73669892-73669972 3.78e-01 80 chr10:71667306-71667386 2.17e-01 19_[+3(2.68e-05)]_32_[+3(2.68e-05)]_\ 13 chr5:149380486-149380566 1.00e-01 25_[+1(1.76e-05)]_47 chr17:74637884-74637964 1.32e-02 72_[+3(2.68e-05)] chr1:154967211-154967291 6.98e-03 22_[+3(3.85e-05)]_50 chr6:170407383-170407463 6.78e-02 13_[+3(9.73e-05)]_59 chr4:140097478-140097558 5.11e-01 80 chr7:155102407-155102487 6.21e-01 80 chr5:149957845-149957925 6.72e-01 80 chr7:151624774-151624854 2.29e-02 80 chr1:113162949-113163029 8.53e-03 46_[+1(4.63e-05)]_26 chr8:39393131-39393211 6.89e-01 80 chr5:176738786-176738866 9.26e-01 80 chr16:46865275-46865355 7.78e-02 44_[+1(7.17e-05)]_28 chr17:25410696-25410776 7.02e-01 80 chr8:143644476-143644556 2.44e-01 1_[+3(8.22e-05)]_12_[+3(6.71e-05)]_\ 51 chr3:58984368-58984448 5.19e-02 80 chr13:61158772-61158852 1.06e-03 45_[+1(6.00e-05)]_27 chr4:187459257-187459337 3.58e-05 34_[+1(3.19e-05)]_38 chr19:11435050-11435130 2.33e-01 80 chrX:64254582-64254662 9.80e-01 80 chr1:6053849-6053929 2.59e-03 37_[+1(6.00e-05)]_35 chr4:100870649-100870729 9.66e-04 80 chr9:119233504-119233584 3.23e-01 80 chr6:31785837-31785917 8.94e-03 21_[+4(2.82e-05)]_51 chr17:62971601-62971681 2.82e-01 80 chr12:112546650-11254673 4.30e-03 14_[+1(7.17e-05)]_58 chr19:36630567-36630647 2.54e-03 29_[+1(1.76e-05)]_43 chr7:155094964-155095044 8.75e-01 80 chr6:14864260-14864340 1.48e-01 80 chr21:47673532-47673612 6.56e-04 22_[+3(4.77e-05)]_50 chr12:6641845-6641925 4.48e-03 27_[+1(6.00e-05)]_20_[+3(3.85e-05)]_\ 17 chr16:68298321-68298401 9.66e-02 58_[+1(1.76e-05)]_14 chr22:19702364-19702444 7.95e-02 65_[+1(1.76e-05)]_7 chr9:135870069-135870149 3.56e-01 80 chr20:37518649-37518729 7.47e-02 80 chr6:31798361-31798441 1.08e-02 31_[+4(4.40e-05)]_[+4(4.40e-05)]_33 chr6:26140626-26140706 7.76e-01 80 chr9:127998696-127998776 8.37e-01 80 chr11:65195884-65195964 8.82e-01 80 chr3:48956164-48956244 1.13e-01 43_[+1(1.76e-05)]_29 chr4:67206196-67206276 4.61e-03 8_[+3(4.77e-05)]_20_[+3(4.77e-05)]_\ 36 chr13:21099342-21099422 1.90e-01 80 chr8:145129275-145129355 6.72e-01 80 chr2:152617051-152617131 1.09e-01 80 chr7:151000918-151000998 9.51e-02 80 chr20:60495000-60495080 2.07e-01 80 chr16:89787714-89787794 6.71e-01 80 chr1:222885459-222885539 9.01e-01 80 chr17:2304873-2304953 1.67e-01 80 chr17:18967101-18967181 4.03e-01 80 chr9:14525975-14526055 2.40e-02 25_[+3(9.73e-05)]_47 chr5:77075013-77075093 7.18e-01 80 chr8:101962757-101962837 2.36e-02 80 chr20:30467646-30467726 5.72e-02 40_[+1(1.76e-05)]_32 chr17:57920564-57920644 7.94e-01 80 chr18:59854213-59854293 1.08e-02 60_[+1(3.19e-05)]_12 chr16:14724260-14724340 2.36e-01 80 chr17:73772635-73772715 7.67e-01 80 chr1:145443016-145443096 1.60e-02 15_[+2(1.44e-05)]_57 chr11:65269120-65269200 6.83e-01 80 chr1:154909738-154909818 1.93e-01 80 chrX:65242028-65242108 7.96e-01 80 chr2:48010334-48010414 8.21e-03 39_[+1(1.76e-05)]_33 chr1:36023592-36023672 3.97e-07 4_[+1(3.19e-05)]_55_[+4(4.40e-05)]_\ 5 chr17:57919943-57920023 3.59e-01 80 chr21:35573876-35573956 3.33e-04 42_[+1(1.76e-05)]_16_[+2(1.44e-05)]_\ 6 chr19:50836718-50836798 3.90e-01 80 chr16:57716832-57716912 1.24e-01 19_[+2(2.95e-05)]_53 chr19:11201253-11201333 2.67e-01 80 chr3:182696418-182696498 3.59e-01 72_[+1(7.17e-05)] chr6:31799485-31799565 3.25e-01 80 chr19:45972746-45972826 7.98e-04 54_[+1(6.00e-05)]_18 chr17:56743892-56743972 8.28e-01 80 chr7:151008747-151008827 7.90e-01 80 chr11:76838515-76838595 1.73e-01 80 chr6:26215989-26216069 3.91e-01 80 chr2:23698908-23698988 5.70e-03 16_[+1(7.17e-05)]_56 chr1:160990819-160990899 1.78e-01 80 chr1:149215151-149215231 9.63e-01 80 chr17:55631081-55631161 9.04e-04 43_[+1(3.19e-05)]_29 chr17:57919705-57919785 6.29e-01 80 chrX:154255419-154255499 2.87e-01 80 chr11:61731544-61731624 8.84e-01 80 chr12:50677197-50677277 4.17e-01 80 chr10:11911279-11911359 7.71e-02 80 chr5:70882896-70882976 4.63e-01 80 chr6:28688439-28688519 9.09e-01 80 chr7:138145730-138145810 3.66e-01 80 chr11:120107452-12010753 8.85e-01 80 chr3:72924737-72924817 1.87e-01 80 chr8:112052397-112052477 5.11e-01 80 chr8:8194470-8194550 2.00e-03 45_[+3(4.77e-05)]_27 chr15:75052786-75052866 4.57e-01 80 chr2:145116805-145116885 9.18e-01 80 chr19:48996360-48996440 3.20e-01 80 chr13:42570250-42570330 2.19e-01 80 chr16:4357900-4357980 1.69e-01 80 chr11:117997321-11799740 9.88e-02 34_[+2(1.44e-05)]_38 chr3:13044222-13044302 3.85e-01 80 chr22:30840951-30841031 4.04e-01 80 chr8:74790254-74790334 1.38e-01 3_[+1(3.19e-05)]_69 chr3:194354375-194354455 3.37e-01 80 chr9:127997668-127997748 5.44e-01 80 chr1:247634513-247634593 3.48e-02 40_[+3(1.51e-05)]_32 chr16:9085961-9086041 9.25e-01 80 chr7:75472493-75472573 3.35e-01 80 chr8:117614900-117614980 3.24e-01 80 chr11:61730838-61730918 2.90e-01 80 chr14:23120349-23120429 6.01e-01 80 chr6:27100297-27100377 6.89e-01 80 chr17:74351148-74351228 3.11e-01 80 chr15:66923217-66923297 5.38e-02 4_[+3(9.73e-05)]_68 chr8:125827857-125827937 7.81e-01 80 chr16:998202-998282 2.59e-01 80 chr11:65270570-65270650 2.86e-02 80 chrX:53711120-53711200 9.83e-04 33_[+1(3.19e-05)]_39 chr1:148604882-148604962 3.40e-01 80 chr15:73669388-73669468 9.56e-01 80 chrX:153191264-153191344 1.87e-01 80 chr2:108363190-108363270 2.65e-01 80 chr1:207779228-207779308 1.21e-01 80 chr5:95064995-95065075 7.47e-01 80 chr17:76136849-76136929 3.44e-03 59_[+2(2.95e-05)]_13 chr22:39189836-39189916 5.10e-03 33_[+1(4.63e-05)]_39 chr1:14762202-14762282 3.43e-01 80 chr15:45019333-45019413 4.41e-03 72_[+5(6.41e-06)] chr11:18127528-18127608 1.50e-02 20_[+1(1.76e-05)]_52 chr7:2272559-2272639 1.21e-02 12_[+1(3.19e-05)]_60 chr3:42642314-42642394 5.18e-02 41_[+1(1.76e-05)]_31 chr3:193660509-193660589 3.65e-01 80 chr1:247634788-247634868 9.27e-02 80 chr7:75933921-75934001 6.22e-01 80 chr2:97202931-97203011 1.04e-03 80 chr2:30884200-30884280 1.06e-02 21_[+5(6.41e-06)]_51 chr6:16215632-16215712 2.46e-02 80 chr3:4345267-4345347 6.31e-04 40_[+4(1.39e-05)]_32 chr9:108457410-108457490 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******************************************************************************** CPU: c17n10.farnam.hpc.yale.internal ********************************************************************************