******************************************************************************** MEME - Motif discovery tool ******************************************************************************** MEME version 5.3.3 (Release date: Sun Feb 7 15:39:52 2021 -0800) For further information on how to interpret these results please access https://meme-suite.org/meme. To get a copy of the MEME Suite software please access https://meme-suite.org. ******************************************************************************** ******************************************************************************** REFERENCE ******************************************************************************** If you use this program in your research, please cite: Timothy L. Bailey and Charles Elkan, "Fitting a mixture model by expectation maximization to discover motifs in biopolymers", Proceedings of the Second International Conference on Intelligent Systems for Molecular Biology, pp. 28-36, AAAI Press, Menlo Park, California, 1994. ******************************************************************************** ******************************************************************************** TRAINING SET ******************************************************************************** PRIMARY SEQUENCES= ../result/final_prediction/K562/fasta/RankLinear0.6_40/TRIP13.fasta CONTROL SEQUENCES= --none-- ALPHABET= ACGT Sequence name Weight Length Sequence name Weight Length ------------- ------ ------ ------------- ------ ------ chr10:119656186-11965626 1.0000 80 chr10:4376481-4376561 1.0000 80 chr21:44612406-44612486 1.0000 80 chr2:101356348-101356428 1.0000 80 chr20:54747785-54747865 1.0000 80 chr2:149838048-149838128 1.0000 80 chr12:115587742-11558782 1.0000 80 chr3:85007866-85007946 1.0000 80 chr4:6179672-6179752 1.0000 80 chr20:45501438-45501518 1.0000 80 chr20:1757974-1758054 1.0000 80 chr1:185663255-185663335 1.0000 80 chr16:84277506-84277586 1.0000 80 chr19:37742713-37742793 1.0000 80 chr1:30417187-30417267 1.0000 80 chr16:86945047-86945127 1.0000 80 chr11:123349168-12334924 1.0000 80 chr2:2061126-2061206 1.0000 80 chr16:5566305-5566385 1.0000 80 chr1:19318258-19318338 1.0000 80 chr7:132242542-132242622 1.0000 80 chr7:6749604-6749684 1.0000 80 chr2:180446439-180446519 1.0000 80 chr16:79444052-79444132 1.0000 80 chr1:237392797-237392877 1.0000 80 chr17:1016169-1016249 1.0000 80 chr19:36822613-36822693 1.0000 80 chr12:113399100-11339918 1.0000 80 chr13:48478577-48478657 1.0000 80 chr5:178587769-178587849 1.0000 80 chr12:105817868-10581794 1.0000 80 chr19:8754986-8755066 1.0000 80 chr21:33406912-33406992 1.0000 80 chr7:4699329-4699409 1.0000 80 chr21:43594400-43594480 1.0000 80 chr6:170475575-170475655 1.0000 80 chr1:5409009-5409089 1.0000 80 chr16:86245591-86245671 1.0000 80 chr17:63382001-63382081 1.0000 80 chr16:50685918-50685998 1.0000 80 chr19:57276640-57276720 1.0000 80 chr19:50679382-50679462 1.0000 80 chr16:86295143-86295223 1.0000 80 chr16:86192454-86192534 1.0000 80 chr6:166901734-166901814 1.0000 80 chr12:4872157-4872237 1.0000 80 chr15:79477771-79477851 1.0000 80 chr8:136685743-136685823 1.0000 80 chr22:43717076-43717156 1.0000 80 chr21:45525417-45525497 1.0000 80 chr20:60000900-60000980 1.0000 80 chr10:4375777-4375857 1.0000 80 chr22:23358782-23358862 1.0000 80 chr2:105593406-105593486 1.0000 80 chr1:37331118-37331198 1.0000 80 chr10:12824677-12824757 1.0000 80 chr17:32080598-32080678 1.0000 80 chr10:30368527-30368607 1.0000 80 chr19:17552370-17552450 1.0000 80 chr3:39527214-39527294 1.0000 80 chr21:18715541-18715621 1.0000 80 chr21:47483346-47483426 1.0000 80 chr19:37808732-37808812 1.0000 80 chr11:60425427-60425507 1.0000 80 chr19:58239033-58239113 1.0000 80 chr10:14420733-14420813 1.0000 80 chr3:11017639-11017719 1.0000 80 chr10:75011880-75011960 1.0000 80 chr16:21716208-21716288 1.0000 80 chr15:70202231-70202311 1.0000 80 chr19:51465632-51465712 1.0000 80 chr10:4446038-4446118 1.0000 80 chr19:46456630-46456710 1.0000 80 chr1:171283153-171283233 1.0000 80 chr7:67383325-67383405 1.0000 80 chr10:49407755-49407835 1.0000 80 chr6:169295357-169295437 1.0000 80 chr19:52956744-52956824 1.0000 80 chr15:69818058-69818138 1.0000 80 chrX:1033532-1033612 1.0000 80 chr2:601090-601170 1.0000 80 chrX:27417139-27417219 1.0000 80 chr20:49609754-49609834 1.0000 80 chr18:61157733-61157813 1.0000 80 chr21:37522659-37522739 1.0000 80 chr20:43858254-43858334 1.0000 80 chr19:10114163-10114243 1.0000 80 chr11:102504368-10250444 1.0000 80 chr16:8561604-8561684 1.0000 80 chr17:2952251-2952331 1.0000 80 chr8:140495754-140495834 1.0000 80 chr11:6846697-6846777 1.0000 80 chr14:76618068-76618148 1.0000 80 chr15:80792030-80792110 1.0000 80 chr2:42068077-42068157 1.0000 80 chr11:45275371-45275451 1.0000 80 chr3:13711956-13712036 1.0000 80 chr16:19165366-19165446 1.0000 80 chr6:51928493-51928573 1.0000 80 chr1:173399480-173399560 1.0000 80 chr2:68515545-68515625 1.0000 80 chr19:6953125-6953205 1.0000 80 chr3:2895578-2895658 1.0000 80 chr12:132076987-13207706 1.0000 80 chr21:32862957-32863037 1.0000 80 chr15:38056962-38057042 1.0000 80 chr17:56307-56387 1.0000 80 chr17:71848258-71848338 1.0000 80 chr8:17549751-17549831 1.0000 80 chr5:140420832-140420912 1.0000 80 chr21:44030005-44030085 1.0000 80 chr16:8438840-8438920 1.0000 80 chr20:39541999-39542079 1.0000 80 chr19:21182656-21182736 1.0000 80 chr19:41173082-41173162 1.0000 80 chr19:51402978-51403058 1.0000 80 chr1:189828752-189828832 1.0000 80 chr1:33704106-33704186 1.0000 80 chr16:67541356-67541436 1.0000 80 chr12:132999960-13300004 1.0000 80 chr16:3481922-3482002 1.0000 80 chr2:356516-356596 1.0000 80 chr16:13228871-13228951 1.0000 80 chr16:27879263-27879343 1.0000 80 chr1:244427627-244427707 1.0000 80 chr10:50543663-50543743 1.0000 80 chr2:25640817-25640897 1.0000 80 chr12:115630264-11563034 1.0000 80 chr2:177646478-177646558 1.0000 80 chr7:127903588-127903668 1.0000 80 chr17:7909360-7909440 1.0000 80 chr12:127944432-12794451 1.0000 80 chr10:50008451-50008531 1.0000 80 chr8:142583645-142583725 1.0000 80 chr17:72355088-72355168 1.0000 80 chr1:29839997-29840077 1.0000 80 chr1:203273920-203274000 1.0000 80 chr1:5782051-5782131 1.0000 80 chr6:168091419-168091499 1.0000 80 chr4:165877999-165878079 1.0000 80 chr8:49419870-49419950 1.0000 80 chr12:107987630-10798771 1.0000 80 chr12:131978149-13197822 1.0000 80 chr6:26576832-26576912 1.0000 80 chr19:17131814-17131894 1.0000 80 chr1:36614423-36614503 1.0000 80 chr1:155050229-155050309 1.0000 80 chr21:39748284-39748364 1.0000 80 chr11:124994188-12499426 1.0000 80 chr15:90692331-90692411 1.0000 80 chr10:28967438-28967518 1.0000 80 chr5:21459515-21459595 1.0000 80 chr5:126560262-126560342 1.0000 80 chr1:220906484-220906564 1.0000 80 chr6:168476477-168476557 1.0000 80 chr6:2784184-2784264 1.0000 80 chr6:157340155-157340235 1.0000 80 chr18:73967148-73967228 1.0000 80 chr10:133622565-13362264 1.0000 80 chr8:143799594-143799674 1.0000 80 chrX:8723333-8723413 1.0000 80 chr20:36857042-36857122 1.0000 80 chr3:4861339-4861419 1.0000 80 chr2:2257496-2257576 1.0000 80 chr19:52901108-52901188 1.0000 80 chr4:6410184-6410264 1.0000 80 chr1:211431503-211431583 1.0000 80 chr17:73088220-73088300 1.0000 80 chr1:52071669-52071749 1.0000 80 chr7:25894460-25894540 1.0000 80 chr17:39789043-39789123 1.0000 80 chr19:57742273-57742353 1.0000 80 chr11:15165601-15165681 1.0000 80 chr9:99776164-99776244 1.0000 80 chr19:13446065-13446145 1.0000 80 chr19:9517707-9517787 1.0000 80 chr20:42846401-42846481 1.0000 80 chr16:6737782-6737862 1.0000 80 chr7:149983393-149983473 1.0000 80 chr19:55959473-55959553 1.0000 80 chr10:132886956-13288703 1.0000 80 chr19:6564606-6564686 1.0000 80 chr19:13755587-13755667 1.0000 80 chr3:44754055-44754135 1.0000 80 chr20:61958493-61958573 1.0000 80 chr16:85450390-85450470 1.0000 80 chr1:171798099-171798179 1.0000 80 chr1:37889607-37889687 1.0000 80 chr19:21541698-21541778 1.0000 80 chr7:130032313-130032393 1.0000 80 chr19:51497560-51497640 1.0000 80 chr1:19007937-19008017 1.0000 80 chr2:70588002-70588082 1.0000 80 chr7:137687490-137687570 1.0000 80 chr16:85995918-85995998 1.0000 80 chr13:92374643-92374723 1.0000 80 chr3:170241121-170241201 1.0000 80 chr2:240832675-240832755 1.0000 80 chr6:58287732-58287812 1.0000 80 chr3:10739824-10739904 1.0000 80 chr19:21105980-21106060 1.0000 80 chr19:7220021-7220101 1.0000 80 chr19:14032088-14032168 1.0000 80 chr14:89498574-89498654 1.0000 80 chr1:105249535-105249615 1.0000 80 chr8:3442532-3442612 1.0000 80 chr4:18077624-18077704 1.0000 80 chr16:88355088-88355168 1.0000 80 chr3:33532430-33532510 1.0000 80 chr11:134314470-13431455 1.0000 80 chr7:6865935-6866015 1.0000 80 chr1:93970323-93970403 1.0000 80 chr8:64304073-64304153 1.0000 80 chr8:102061435-102061515 1.0000 80 chr10:74032135-74032215 1.0000 80 chr6:151710294-151710374 1.0000 80 chr11:40315682-40315762 1.0000 80 chr12:131365735-13136581 1.0000 80 chr1:17059456-17059536 1.0000 80 chr12:38710446-38710526 1.0000 80 chr19:40562081-40562161 1.0000 80 chr22:46376796-46376876 1.0000 80 chr19:21579796-21579876 1.0000 80 chr11:45615672-45615752 1.0000 80 chr19:48453532-48453612 1.0000 80 chr3:10636745-10636825 1.0000 80 chr12:131239160-13123924 1.0000 80 chr11:128027861-12802794 1.0000 80 chr19:12202911-12202991 1.0000 80 chr7:87506567-87506647 1.0000 80 chr12:130991548-13099162 1.0000 80 chr1:224545544-224545624 1.0000 80 chr6:34038999-34039079 1.0000 80 chr6:31370541-31370621 1.0000 80 chr15:90000481-90000561 1.0000 80 chr1:217804470-217804550 1.0000 80 chr7:158500511-158500591 1.0000 80 chr14:106097241-10609732 1.0000 80 chr7:100825924-100826004 1.0000 80 chr22:47666361-47666441 1.0000 80 chr2:149403864-149403944 1.0000 80 chr19:20844415-20844495 1.0000 80 chr7:126747877-126747957 1.0000 80 chr6:10403612-10403692 1.0000 80 chr11:129684710-12968479 1.0000 80 chr19:2375538-2375618 1.0000 80 chr2:220042428-220042508 1.0000 80 chr22:21192832-21192912 1.0000 80 chr9:100034206-100034286 1.0000 80 chr16:49958144-49958224 1.0000 80 ******************************************************************************** ******************************************************************************** COMMAND LINE SUMMARY ******************************************************************************** This information can also be useful in the event you wish to report a problem with the MEME software. command: meme -oc ../result/final_prediction/K562/inference_raw/MEME/RankLinear0.6_40_TRIP13/ -dna -nmotifs 5 -w 8 -maxsize 250000 -nostatus ../result/final_prediction/K562/fasta/RankLinear0.6_40/TRIP13.fasta model: mod= zoops nmotifs= 5 evt= inf objective function: em= E-value of product of p-values starts= E-value of product of p-values strands: + width: minw= 8 maxw= 8 nsites: minsites= 2 maxsites= 250 wnsites= 0.8 theta: spmap= uni spfuzz= 0.5 em: prior= dirichlet b= 0.01 maxiter= 50 distance= 1e-05 trim: wg= 11 ws= 1 endgaps= yes data: n= 20000 N= 250 sample: seed= 0 hsfrac= 0 searchsize= 20000 norand= no csites= 1000 Letter frequencies in dataset: A 0.238 C 0.253 G 0.249 T 0.26 Background letter frequencies (from file dataset with add-one prior applied): A 0.238 C 0.253 G 0.249 T 0.26 Background model order: 0 ******************************************************************************** ******************************************************************************** MOTIF CTGATTGG MEME-1 width = 8 sites = 72 llr = 609 E-value = 7.6e-048 ******************************************************************************** -------------------------------------------------------------------------------- Motif CTGATTGG MEME-1 Description -------------------------------------------------------------------------------- Simplified A 11:a:::: pos.-specific C 613::::: probability G 3:7:::aa matrix T 19::9a:: bits 2.1 * * 1.9 * *** 1.7 ***** 1.4 ***** Relative 1.2 * ***** Entropy 1.0 ******* (12.2 bits) 0.8 ******* 0.6 ******* 0.4 ******** 0.2 ******** 0.0 -------- Multilevel CTGATTGG consensus G C sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTGATTGG MEME-1 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr16:49958144-49958224 35 1.63e-05 acggaatatg ctgattgg ccaggcccaa chr11:129684710-12968479 24 1.63e-05 ttacagagtg ctgattgg tccgttttta chr19:20844415-20844495 12 1.63e-05 AGCTGCGTTC CTGATTGG ATGGTTTCCA chr7:158500511-158500591 64 1.63e-05 gaagtgtgtg ctgattgg cccatgggc chr11:40315682-40315762 58 1.63e-05 CATCTTAGCA CTGATTGG TCAATTGCAT chr16:88355088-88355168 30 1.63e-05 CAGGCCTCAC CTGATTGG ATGCAGCCCT chr1:105249535-105249615 53 1.63e-05 gttggTGGGC CTGATTGG TTAAAAACAT chr19:7220021-7220101 18 1.63e-05 attaagaaag ctgattgg cccagtctga chr2:240832675-240832755 36 1.63e-05 CAGAAGggct ctgattgg cccagcgtgg chr19:51497560-51497640 25 1.63e-05 caagtagcca ctgattgg ctaagatttg chr19:13755587-13755667 67 1.63e-05 atggggtatg ctgattgg cctaaa chr19:6564606-6564686 47 1.63e-05 CAGGGGAGAG CTGATTGG CTGGATTAGT chr11:15165601-15165681 3 1.63e-05 gc ctgattgg tggcacctaa chr1:29839997-29840077 49 1.63e-05 GGAATTCAGC ctgattgg ctcagattgg chr8:142583645-142583725 35 1.63e-05 actcttcatc ctgattgg tcccctcatg chr15:70202231-70202311 14 1.63e-05 gtagagaatt ctgattgg ctaagctcag chr16:21716208-21716288 27 1.63e-05 aggactcatt ctgattgg atcgtggacc chr10:14420733-14420813 10 1.63e-05 gggctcaat ctgattgg atcttggatc chr21:47483346-47483426 20 1.63e-05 cagaaacagc ctgattgg ctacagctgg chr3:39527214-39527294 27 1.63e-05 GCCAGTGCCT CTGATTGG CTGCTTTCCC chr21:43594400-43594480 54 1.63e-05 aggagagagt ctgattgg tccagcctga chr10:119656186-11965626 29 1.63e-05 ggggctggcc ctgattgg cctgtcataa chr19:2375538-2375618 24 3.24e-05 GGTGGGAACT GTGATTGG CAGGCCAGGG chr12:130991548-13099162 71 3.24e-05 cctggatgtg gtgattgg tt chr11:45615672-45615752 8 3.24e-05 ggccaca gtgattgg ttcagggata chr20:36857042-36857122 29 3.24e-05 cctctggcca gtgattgg tttagatggg chr5:126560262-126560342 48 3.24e-05 taaattccct gtgattgg ttcagaggtg chr19:17131814-17131894 66 3.24e-05 tctggtcata gtgattgg ctcaggg chr12:131978149-13197822 58 3.24e-05 ctctggacca gtgattgg tgcagggctg chr4:165877999-165878079 71 3.24e-05 CGGCAGAGCA GTGATTGG GT chr1:5782051-5782131 8 3.24e-05 ggccata gtgattgg tccagcaatg chr1:33704106-33704186 11 3.24e-05 gtgaggtgct gtgattgg ccaagcctag chr17:56307-56387 34 3.24e-05 ATGGGGAAAC GTGATTGG ACGAATGTTT chr12:132076987-13207706 7 3.24e-05 tggtta gtgattgg cccagggatg chr15:69818058-69818138 18 3.24e-05 tcccttgtca gtgattgg tctagaggta chr19:17552370-17552450 13 3.24e-05 cctgatgtta gtgattgg tggaggaata chr19:8754986-8755066 12 3.24e-05 tttggttaca gtgattgg ctcaggagtg chr15:90000481-90000561 59 4.90e-05 tccacttcca ctcattgg ccacagtttg chr21:44030005-44030085 26 4.90e-05 gtgctcacag ctcattgg ccacagcagc chr17:2952251-2952331 30 4.90e-05 TTTCCATCTC CTCATTGG CTGTCGCCTC chr19:58239033-58239113 25 4.90e-05 CTCCTGGGCC CTCATTGG GTATGCAACG chr21:33406912-33406992 12 4.90e-05 cctcctattt ctcattgg ccagcaaggt chr7:6749604-6749684 1 4.90e-05 . ctcattgg ttcctggctc chr19:51402978-51403058 59 6.54e-05 taacttccag gtcattgg catggaaagg chr3:10739824-10739904 4 8.07e-05 gcc atgattgg tttaggcatg chr15:80792030-80792110 45 8.07e-05 gtgagttact atgattgg cccagggtgt chr1:19318258-19318338 19 8.07e-05 tttgaccatc atgattgg ttcagaaatg chr3:10636745-10636825 41 9.75e-05 TGCCTCTGAG TTGATTGG CTCCAGGATG chr3:11017639-11017719 49 9.75e-05 aggatttatt ttgattgg accagcttgg chr14:89498574-89498654 17 1.44e-04 cttctactct atcattgg tcagaaccag chr11:124994188-12499426 21 1.44e-04 GGACTTTCCT ATCATTGG TTCCAAAGCT chr19:51465632-51465712 43 1.44e-04 GTCCACCTCC ATCATTGG TCCTTTTCTA chr16:85995918-85995998 42 1.61e-04 cgtctcacat ttcattgg tcagaactgg chr10:133622565-13362264 62 1.61e-04 gtacttgaat ttcattgg ccaaggcaag chr12:132999960-13300004 23 1.61e-04 AGGCCTGGCT TTCATTGG GCTAGCTTGG chr1:237392797-237392877 35 1.61e-04 GTACATTGAA TTCATTGG TTGGTGACCC chr20:45501438-45501518 19 1.92e-04 GAACTGACTG CTGAATGG AACAGACTCA chr3:85007866-85007946 65 1.92e-04 GCCAGGGGTG CTGAATGG GGGCTTCA chr19:14032088-14032168 13 2.08e-04 ttgcttgtct cccattgg ccagaactaa chr7:127903588-127903668 50 2.08e-04 agagctgact cccattgg tctggcttga chr16:8438840-8438920 23 2.08e-04 cctttaagat cccattgg tcagaactgc chr19:37808732-37808812 22 2.08e-04 GATCGCGTTT CCCATTGG TCGCCGTTTC chr16:50685918-50685998 32 2.08e-04 taacttccat cccattgg ccaaagcaag chr19:37742713-37742793 33 2.08e-04 GGTCGCGTTT CCCATTGG TCACCGTTTC chr19:13446065-13446145 71 2.23e-04 aggtatccac gagattgg aa chr11:102504368-10250444 56 2.23e-04 TTTGGGATTA GAGATTGG GCTCTTTCTG chr6:31370541-31370621 17 2.53e-04 GTAGATCTCT CACATTGG AGGGGACTAT chr3:170241121-170241201 67 2.53e-04 atatcttgac ctgattga caattc chr17:71848258-71848338 73 2.53e-04 tcacattggt cacattgg chr8:136685743-136685823 41 2.53e-04 GTGATGCACT CTGATTGA ACAGCCTTCA chr22:23358782-23358862 14 3.60e-04 tgacaggttg ctgactgg tgcgtttaca chr7:137687490-137687570 3 4.37e-04 GA GTCAATGG CATGCTTTTC -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTGATTGG MEME-1 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr16:49958144-49958224 1.6e-05 34_[+1]_38 chr11:129684710-12968479 1.6e-05 23_[+1]_49 chr19:20844415-20844495 1.6e-05 11_[+1]_61 chr7:158500511-158500591 1.6e-05 63_[+1]_9 chr11:40315682-40315762 1.6e-05 57_[+1]_15 chr16:88355088-88355168 1.6e-05 29_[+1]_43 chr1:105249535-105249615 1.6e-05 52_[+1]_20 chr19:7220021-7220101 1.6e-05 17_[+1]_55 chr2:240832675-240832755 1.6e-05 35_[+1]_37 chr19:51497560-51497640 1.6e-05 24_[+1]_48 chr19:13755587-13755667 1.6e-05 66_[+1]_6 chr19:6564606-6564686 1.6e-05 46_[+1]_26 chr11:15165601-15165681 1.6e-05 2_[+1]_70 chr1:29839997-29840077 1.6e-05 48_[+1]_24 chr8:142583645-142583725 1.6e-05 34_[+1]_38 chr15:70202231-70202311 1.6e-05 13_[+1]_59 chr16:21716208-21716288 1.6e-05 26_[+1]_46 chr10:14420733-14420813 1.6e-05 9_[+1]_63 chr21:47483346-47483426 1.6e-05 19_[+1]_53 chr3:39527214-39527294 1.6e-05 26_[+1]_46 chr21:43594400-43594480 1.6e-05 53_[+1]_19 chr10:119656186-11965626 1.6e-05 28_[+1]_44 chr19:2375538-2375618 3.2e-05 23_[+1]_49 chr12:130991548-13099162 3.2e-05 70_[+1]_2 chr11:45615672-45615752 3.2e-05 7_[+1]_65 chr20:36857042-36857122 3.2e-05 28_[+1]_44 chr5:126560262-126560342 3.2e-05 47_[+1]_25 chr19:17131814-17131894 3.2e-05 65_[+1]_7 chr12:131978149-13197822 3.2e-05 57_[+1]_15 chr4:165877999-165878079 3.2e-05 70_[+1]_2 chr1:5782051-5782131 3.2e-05 7_[+1]_65 chr1:33704106-33704186 3.2e-05 10_[+1]_62 chr17:56307-56387 3.2e-05 33_[+1]_39 chr12:132076987-13207706 3.2e-05 6_[+1]_66 chr15:69818058-69818138 3.2e-05 17_[+1]_55 chr19:17552370-17552450 3.2e-05 12_[+1]_60 chr19:8754986-8755066 3.2e-05 11_[+1]_61 chr15:90000481-90000561 4.9e-05 58_[+1]_14 chr21:44030005-44030085 4.9e-05 25_[+1]_47 chr17:2952251-2952331 4.9e-05 29_[+1]_43 chr19:58239033-58239113 4.9e-05 24_[+1]_48 chr21:33406912-33406992 4.9e-05 11_[+1]_61 chr7:6749604-6749684 4.9e-05 [+1]_72 chr19:51402978-51403058 6.5e-05 58_[+1]_14 chr3:10739824-10739904 8.1e-05 3_[+1]_69 chr15:80792030-80792110 8.1e-05 44_[+1]_28 chr1:19318258-19318338 8.1e-05 18_[+1]_54 chr3:10636745-10636825 9.8e-05 40_[+1]_32 chr3:11017639-11017719 9.8e-05 48_[+1]_24 chr14:89498574-89498654 0.00014 16_[+1]_56 chr11:124994188-12499426 0.00014 20_[+1]_52 chr19:51465632-51465712 0.00014 42_[+1]_30 chr16:85995918-85995998 0.00016 41_[+1]_31 chr10:133622565-13362264 0.00016 61_[+1]_11 chr12:132999960-13300004 0.00016 22_[+1]_50 chr1:237392797-237392877 0.00016 34_[+1]_38 chr20:45501438-45501518 0.00019 18_[+1]_54 chr3:85007866-85007946 0.00019 64_[+1]_8 chr19:14032088-14032168 0.00021 12_[+1]_60 chr7:127903588-127903668 0.00021 49_[+1]_23 chr16:8438840-8438920 0.00021 22_[+1]_50 chr19:37808732-37808812 0.00021 21_[+1]_51 chr16:50685918-50685998 0.00021 31_[+1]_41 chr19:37742713-37742793 0.00021 32_[+1]_40 chr19:13446065-13446145 0.00022 70_[+1]_2 chr11:102504368-10250444 0.00022 55_[+1]_17 chr6:31370541-31370621 0.00025 16_[+1]_56 chr3:170241121-170241201 0.00025 66_[+1]_6 chr17:71848258-71848338 0.00025 72_[+1] chr8:136685743-136685823 0.00025 40_[+1]_32 chr22:23358782-23358862 0.00036 13_[+1]_59 chr7:137687490-137687570 0.00044 2_[+1]_70 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTGATTGG MEME-1 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF CTGATTGG width=8 seqs=72 chr16:49958144-49958224 ( 35) CTGATTGG 1 chr11:129684710-12968479 ( 24) CTGATTGG 1 chr19:20844415-20844495 ( 12) CTGATTGG 1 chr7:158500511-158500591 ( 64) CTGATTGG 1 chr11:40315682-40315762 ( 58) CTGATTGG 1 chr16:88355088-88355168 ( 30) CTGATTGG 1 chr1:105249535-105249615 ( 53) CTGATTGG 1 chr19:7220021-7220101 ( 18) CTGATTGG 1 chr2:240832675-240832755 ( 36) CTGATTGG 1 chr19:51497560-51497640 ( 25) CTGATTGG 1 chr19:13755587-13755667 ( 67) CTGATTGG 1 chr19:6564606-6564686 ( 47) CTGATTGG 1 chr11:15165601-15165681 ( 3) CTGATTGG 1 chr1:29839997-29840077 ( 49) CTGATTGG 1 chr8:142583645-142583725 ( 35) CTGATTGG 1 chr15:70202231-70202311 ( 14) CTGATTGG 1 chr16:21716208-21716288 ( 27) CTGATTGG 1 chr10:14420733-14420813 ( 10) CTGATTGG 1 chr21:47483346-47483426 ( 20) CTGATTGG 1 chr3:39527214-39527294 ( 27) CTGATTGG 1 chr21:43594400-43594480 ( 54) CTGATTGG 1 chr10:119656186-11965626 ( 29) CTGATTGG 1 chr19:2375538-2375618 ( 24) GTGATTGG 1 chr12:130991548-13099162 ( 71) GTGATTGG 1 chr11:45615672-45615752 ( 8) GTGATTGG 1 chr20:36857042-36857122 ( 29) GTGATTGG 1 chr5:126560262-126560342 ( 48) GTGATTGG 1 chr19:17131814-17131894 ( 66) GTGATTGG 1 chr12:131978149-13197822 ( 58) GTGATTGG 1 chr4:165877999-165878079 ( 71) GTGATTGG 1 chr1:5782051-5782131 ( 8) GTGATTGG 1 chr1:33704106-33704186 ( 11) GTGATTGG 1 chr17:56307-56387 ( 34) GTGATTGG 1 chr12:132076987-13207706 ( 7) GTGATTGG 1 chr15:69818058-69818138 ( 18) GTGATTGG 1 chr19:17552370-17552450 ( 13) GTGATTGG 1 chr19:8754986-8755066 ( 12) GTGATTGG 1 chr15:90000481-90000561 ( 59) CTCATTGG 1 chr21:44030005-44030085 ( 26) CTCATTGG 1 chr17:2952251-2952331 ( 30) CTCATTGG 1 chr19:58239033-58239113 ( 25) CTCATTGG 1 chr21:33406912-33406992 ( 12) CTCATTGG 1 chr7:6749604-6749684 ( 1) CTCATTGG 1 chr19:51402978-51403058 ( 59) GTCATTGG 1 chr3:10739824-10739904 ( 4) ATGATTGG 1 chr15:80792030-80792110 ( 45) ATGATTGG 1 chr1:19318258-19318338 ( 19) ATGATTGG 1 chr3:10636745-10636825 ( 41) TTGATTGG 1 chr3:11017639-11017719 ( 49) TTGATTGG 1 chr14:89498574-89498654 ( 17) ATCATTGG 1 chr11:124994188-12499426 ( 21) ATCATTGG 1 chr19:51465632-51465712 ( 43) ATCATTGG 1 chr16:85995918-85995998 ( 42) TTCATTGG 1 chr10:133622565-13362264 ( 62) TTCATTGG 1 chr12:132999960-13300004 ( 23) TTCATTGG 1 chr1:237392797-237392877 ( 35) TTCATTGG 1 chr20:45501438-45501518 ( 19) CTGAATGG 1 chr3:85007866-85007946 ( 65) CTGAATGG 1 chr19:14032088-14032168 ( 13) CCCATTGG 1 chr7:127903588-127903668 ( 50) CCCATTGG 1 chr16:8438840-8438920 ( 23) CCCATTGG 1 chr19:37808732-37808812 ( 22) CCCATTGG 1 chr16:50685918-50685998 ( 32) CCCATTGG 1 chr19:37742713-37742793 ( 33) CCCATTGG 1 chr19:13446065-13446145 ( 71) GAGATTGG 1 chr11:102504368-10250444 ( 56) GAGATTGG 1 chr6:31370541-31370621 ( 17) CACATTGG 1 chr3:170241121-170241201 ( 67) CTGATTGA 1 chr17:71848258-71848338 ( 73) CACATTGG 1 chr8:136685743-136685823 ( 41) CTGATTGA 1 chr22:23358782-23358862 ( 14) CTGACTGG 1 chr7:137687490-137687570 ( 3) GTCAATGG 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTGATTGG MEME-1 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 8.83052 E= 7.6e-048 -152 117 8 -164 -210 -160 -1281 173 -1281 34 145 -1281 207 -1281 -1281 -1281 -252 -418 -1281 186 -1281 -1281 -1281 195 -1281 -1281 200 -1281 -310 -1281 196 -1281 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTGATTGG MEME-1 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 72 E= 7.6e-048 0.083333 0.569444 0.263889 0.083333 0.055556 0.083333 0.000000 0.861111 0.000000 0.319444 0.680556 0.000000 1.000000 0.000000 0.000000 0.000000 0.041667 0.013889 0.000000 0.944444 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.027778 0.000000 0.972222 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTGATTGG MEME-1 regular expression -------------------------------------------------------------------------------- [CG]T[GC]ATTGG -------------------------------------------------------------------------------- Time 4.88 secs. ******************************************************************************** ******************************************************************************** MOTIF ACMGGAAG MEME-2 width = 8 sites = 56 llr = 479 E-value = 3.0e-030 ******************************************************************************** -------------------------------------------------------------------------------- Motif ACMGGAAG MEME-2 Description -------------------------------------------------------------------------------- Simplified A 616::aa: pos.-specific C 164::::: probability G 22:aa::a matrix T 1::::::: bits 2.1 ***** 1.9 ***** 1.7 ***** 1.4 ***** Relative 1.2 ***** Entropy 1.0 ****** (12.4 bits) 0.8 ****** 0.6 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel ACAGGAAG consensus GC sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ACMGGAAG MEME-2 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr14:106097241-10609732 39 1.25e-05 CCAGCATGGA ACAGGAAG CATCCAGCAT chr12:131239160-13123924 11 1.25e-05 aagtgaatga acaggaag tgaggcagga chr19:40562081-40562161 40 1.25e-05 ACCCCAGGAG ACAGGAAG TGGAACCGCT chr2:2257496-2257576 44 1.25e-05 CAAGTCGGAA ACAGGAAG CGGGGCAGGA chr21:39748284-39748364 34 1.25e-05 GCTCTCTTTC ACAGGAAG AGGCGGGTCC chr17:72355088-72355168 7 1.25e-05 gggtta acaggaag accctttttg chr10:50008451-50008531 26 1.25e-05 AAGGGAATGG ACAGGAAG CTGTGAGGGA chr2:177646478-177646558 48 1.25e-05 GTAGTATCTG ACAGGAAG TAGAGGGCAG chr21:32862957-32863037 39 1.25e-05 atggaacaag acaggaag tagactgggg chr7:67383325-67383405 65 1.25e-05 CGATTCTGAA ACAGGAAG TGAGATGG chr2:105593406-105593486 37 1.25e-05 ctggaaggaa acaggaag gagccaggtc chr19:50679382-50679462 5 1.25e-05 catg acAGGAAG TACAATCTTA chr7:4699329-4699409 32 1.25e-05 caaggctgga acaggaag gaagaatttc chr1:185663255-185663335 42 1.25e-05 ttcgtccaga acaggaag cggaagttct chr2:240832675-240832755 10 2.59e-05 GCACAGAGG ACCGGAAG TATGTGCACA chr8:143799594-143799674 47 2.59e-05 tgggaaagaa accggaag caaactgaaa chr16:3481922-3482002 21 2.59e-05 GGAAGCGGGC ACCGGAAG TGGCTCGGCT chr19:10114163-10114243 48 2.59e-05 GGTGGTCAAA ACCGGAAG TGAGAGGTCT chr10:12824677-12824757 7 2.59e-05 TCAAGG ACCGGAAG ACCAGCTGTG chr22:43717076-43717156 64 2.59e-05 ACTAAGTGGA ACCGGAAG TGCATCTCA chr16:86192454-86192534 54 2.59e-05 gaagctgaat accggaag agaatgacgt chr1:30417187-30417267 30 2.59e-05 gtgtagcgga accggaag ggcagtgagg chr12:115587742-11558782 50 2.59e-05 tcctgtgtgt accggaag aggaaatgac chr19:12202911-12202991 39 3.82e-05 TGGGCCTTAA AGAGGAAG TGAATAGAAC chr1:171798099-171798179 56 3.82e-05 cagaaaaaaa agaggaag tgatgatgat chr2:25640817-25640897 29 3.82e-05 aatgaaatgg agaggaag tgatgcgtgt chr19:21182656-21182736 50 3.82e-05 TCACAGCCAG AGAGGAAG GGGCGGCTCC chr19:46456630-46456710 57 5.13e-05 TCCGGTGATA GCAGGAAG TGGGAGGCAG chr4:165877999-165878079 47 6.44e-05 GCGAGTCCGT AGCGGAAG TCGGAGCGGC chr11:45275371-45275451 61 6.44e-05 atgggatgca agcggaag tgacgtccac chr14:89498574-89498654 62 7.77e-05 cacgtgcgga ccaggaag tgcaacccta chr5:178587769-178587849 45 7.77e-05 cccatcatga ccaggaag agcatgtgac chr7:132242542-132242622 25 7.77e-05 GCAGACTTCG CCAGGAAG CTACTTCCCA chr1:52071669-52071749 23 1.03e-04 agaaaaaaga aaaggaag gaaagaaagg chr18:73967148-73967228 53 1.03e-04 CCCGTACTTA GCCGGAAG TGTGTCTGTC chr1:33704106-33704186 66 1.03e-04 ATGCAGCTAG AAAGGAAG GGTCATG chrX:1033532-1033612 16 1.03e-04 atggcaacac gccggaag taccgccccc chr21:33406912-33406992 64 1.03e-04 tcactaatca aaaggaag gtgattgca chr16:84277506-84277586 21 1.03e-04 CCAATCAGAC AAAGGAAG GACACCTACC chr19:52901108-52901188 7 1.18e-04 GGTAGA CCCGGAAG CCGATTGCAG chr20:39541999-39542079 39 1.18e-04 CTAGGAGTGA CCCGGAAG TCCATGCCAC chr19:52956744-52956824 25 1.18e-04 TTCCTGGAAA CCCGGAAG TGAATCATGG chr1:237392797-237392877 50 1.18e-04 TGGTTGGTGA CCCGGAAG TGACCCTATA chr6:10403612-10403692 67 1.43e-04 TGACTGTGCA GGAGGAAG AAAAGA chr7:158500511-158500591 50 1.43e-04 tccatagaca ggaggaag tgtgtgctga chr3:4861339-4861419 34 1.43e-04 TGGGGAACCC GGAGGAAG GGACTTCTGG chr8:140495754-140495834 25 1.43e-04 gctgagagaa ggaggaag aagggacttg chr17:32080598-32080678 24 1.43e-04 gccgtgtggt ggaggaag attcatacac chr20:1757974-1758054 31 1.84e-04 ATCCCAGCCG GGCGGAAG GAGCGCCGCC chr12:115630264-11563034 72 2.09e-04 AACTGGCCCA ATAGGAAG G chr1:244427627-244427707 26 2.09e-04 TGGGTGAAGG GAAGGAAG TGTGCTTGGG chr10:4446038-4446118 51 2.09e-04 ctgctgagac ataggaag ctatgcccat chr19:37808732-37808812 60 2.23e-04 CCCTCCCGTT TCCGGAAG CCCGGCACAG chr19:37742713-37742793 49 2.23e-04 GGTCACCGTT TCCGGAAG CCCGCCCCCA chr8:17549751-17549831 47 2.77e-04 cggccaatga gacggaag cttaagcgac chr5:126560262-126560342 64 2.90e-04 ggttcagagg tgaggaag tgacctaat -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ACMGGAAG MEME-2 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr14:106097241-10609732 1.3e-05 38_[+2]_34 chr12:131239160-13123924 1.3e-05 10_[+2]_62 chr19:40562081-40562161 1.3e-05 39_[+2]_33 chr2:2257496-2257576 1.3e-05 43_[+2]_29 chr21:39748284-39748364 1.3e-05 33_[+2]_39 chr17:72355088-72355168 1.3e-05 6_[+2]_66 chr10:50008451-50008531 1.3e-05 25_[+2]_47 chr2:177646478-177646558 1.3e-05 47_[+2]_25 chr21:32862957-32863037 1.3e-05 38_[+2]_34 chr7:67383325-67383405 1.3e-05 64_[+2]_8 chr2:105593406-105593486 1.3e-05 36_[+2]_36 chr19:50679382-50679462 1.3e-05 4_[+2]_68 chr7:4699329-4699409 1.3e-05 31_[+2]_41 chr1:185663255-185663335 1.3e-05 41_[+2]_31 chr2:240832675-240832755 2.6e-05 9_[+2]_63 chr8:143799594-143799674 2.6e-05 46_[+2]_26 chr16:3481922-3482002 2.6e-05 20_[+2]_52 chr19:10114163-10114243 2.6e-05 47_[+2]_25 chr10:12824677-12824757 2.6e-05 6_[+2]_66 chr22:43717076-43717156 2.6e-05 63_[+2]_9 chr16:86192454-86192534 2.6e-05 53_[+2]_19 chr1:30417187-30417267 2.6e-05 29_[+2]_43 chr12:115587742-11558782 2.6e-05 49_[+2]_23 chr19:12202911-12202991 3.8e-05 38_[+2]_34 chr1:171798099-171798179 3.8e-05 55_[+2]_17 chr2:25640817-25640897 3.8e-05 28_[+2]_44 chr19:21182656-21182736 3.8e-05 49_[+2]_23 chr19:46456630-46456710 5.1e-05 56_[+2]_16 chr4:165877999-165878079 6.4e-05 46_[+2]_26 chr11:45275371-45275451 6.4e-05 60_[+2]_12 chr14:89498574-89498654 7.8e-05 61_[+2]_11 chr5:178587769-178587849 7.8e-05 44_[+2]_28 chr7:132242542-132242622 7.8e-05 24_[+2]_48 chr1:52071669-52071749 0.0001 22_[+2]_50 chr18:73967148-73967228 0.0001 52_[+2]_20 chr1:33704106-33704186 0.0001 65_[+2]_7 chrX:1033532-1033612 0.0001 15_[+2]_57 chr21:33406912-33406992 0.0001 63_[+2]_9 chr16:84277506-84277586 0.0001 20_[+2]_52 chr19:52901108-52901188 0.00012 6_[+2]_66 chr20:39541999-39542079 0.00012 38_[+2]_34 chr19:52956744-52956824 0.00012 24_[+2]_48 chr1:237392797-237392877 0.00012 49_[+2]_23 chr6:10403612-10403692 0.00014 66_[+2]_6 chr7:158500511-158500591 0.00014 49_[+2]_23 chr3:4861339-4861419 0.00014 33_[+2]_39 chr8:140495754-140495834 0.00014 24_[+2]_48 chr17:32080598-32080678 0.00014 23_[+2]_49 chr20:1757974-1758054 0.00018 30_[+2]_42 chr12:115630264-11563034 0.00021 71_[+2]_1 chr1:244427627-244427707 0.00021 25_[+2]_47 chr10:4446038-4446118 0.00021 50_[+2]_22 chr19:37808732-37808812 0.00022 59_[+2]_13 chr19:37742713-37742793 0.00022 48_[+2]_24 chr8:17549751-17549831 0.00028 46_[+2]_26 chr5:126560262-126560342 0.00029 63_[+2]_9 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ACMGGAAG MEME-2 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF ACMGGAAG width=8 seqs=56 chr14:106097241-10609732 ( 39) ACAGGAAG 1 chr12:131239160-13123924 ( 11) ACAGGAAG 1 chr19:40562081-40562161 ( 40) ACAGGAAG 1 chr2:2257496-2257576 ( 44) ACAGGAAG 1 chr21:39748284-39748364 ( 34) ACAGGAAG 1 chr17:72355088-72355168 ( 7) ACAGGAAG 1 chr10:50008451-50008531 ( 26) ACAGGAAG 1 chr2:177646478-177646558 ( 48) ACAGGAAG 1 chr21:32862957-32863037 ( 39) ACAGGAAG 1 chr7:67383325-67383405 ( 65) ACAGGAAG 1 chr2:105593406-105593486 ( 37) ACAGGAAG 1 chr19:50679382-50679462 ( 5) ACAGGAAG 1 chr7:4699329-4699409 ( 32) ACAGGAAG 1 chr1:185663255-185663335 ( 42) ACAGGAAG 1 chr2:240832675-240832755 ( 10) ACCGGAAG 1 chr8:143799594-143799674 ( 47) ACCGGAAG 1 chr16:3481922-3482002 ( 21) ACCGGAAG 1 chr19:10114163-10114243 ( 48) ACCGGAAG 1 chr10:12824677-12824757 ( 7) ACCGGAAG 1 chr22:43717076-43717156 ( 64) ACCGGAAG 1 chr16:86192454-86192534 ( 54) ACCGGAAG 1 chr1:30417187-30417267 ( 30) ACCGGAAG 1 chr12:115587742-11558782 ( 50) ACCGGAAG 1 chr19:12202911-12202991 ( 39) AGAGGAAG 1 chr1:171798099-171798179 ( 56) AGAGGAAG 1 chr2:25640817-25640897 ( 29) AGAGGAAG 1 chr19:21182656-21182736 ( 50) AGAGGAAG 1 chr19:46456630-46456710 ( 57) GCAGGAAG 1 chr4:165877999-165878079 ( 47) AGCGGAAG 1 chr11:45275371-45275451 ( 61) AGCGGAAG 1 chr14:89498574-89498654 ( 62) CCAGGAAG 1 chr5:178587769-178587849 ( 45) CCAGGAAG 1 chr7:132242542-132242622 ( 25) CCAGGAAG 1 chr1:52071669-52071749 ( 23) AAAGGAAG 1 chr18:73967148-73967228 ( 53) GCCGGAAG 1 chr1:33704106-33704186 ( 66) AAAGGAAG 1 chrX:1033532-1033612 ( 16) GCCGGAAG 1 chr21:33406912-33406992 ( 64) AAAGGAAG 1 chr16:84277506-84277586 ( 21) AAAGGAAG 1 chr19:52901108-52901188 ( 7) CCCGGAAG 1 chr20:39541999-39542079 ( 39) CCCGGAAG 1 chr19:52956744-52956824 ( 25) CCCGGAAG 1 chr1:237392797-237392877 ( 50) CCCGGAAG 1 chr6:10403612-10403692 ( 67) GGAGGAAG 1 chr7:158500511-158500591 ( 50) GGAGGAAG 1 chr3:4861339-4861419 ( 34) GGAGGAAG 1 chr8:140495754-140495834 ( 25) GGAGGAAG 1 chr17:32080598-32080678 ( 24) GGAGGAAG 1 chr20:1757974-1758054 ( 31) GGCGGAAG 1 chr12:115630264-11563034 ( 72) ATAGGAAG 1 chr1:244427627-244427707 ( 26) GAAGGAAG 1 chr10:4446038-4446118 ( 51) ATAGGAAG 1 chr19:37808732-37808812 ( 60) TCCGGAAG 1 chr19:37742713-37742793 ( 49) TCCGGAAG 1 chr8:17549751-17549831 ( 47) GACGGAAG 1 chr5:126560262-126560342 ( 64) TGAGGAAG 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ACMGGAAG MEME-2 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 10.3065 E= 3.0e-030 139 -101 -34 -228 -115 131 -10 -286 139 57 -1245 -1245 -1245 -1245 200 -1245 -1245 -1245 200 -1245 207 -1245 -1245 -1245 207 -1245 -1245 -1245 -1245 -1245 200 -1245 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ACMGGAAG MEME-2 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 56 E= 3.0e-030 0.625000 0.125000 0.196429 0.053571 0.107143 0.625000 0.232143 0.035714 0.625000 0.375000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ACMGGAAG MEME-2 regular expression -------------------------------------------------------------------------------- A[CG][AC]GGAAG -------------------------------------------------------------------------------- Time 8.54 secs. ******************************************************************************** ******************************************************************************** MOTIF ACTTCCKG MEME-3 width = 8 sites = 85 llr = 627 E-value = 3.3e-025 ******************************************************************************** -------------------------------------------------------------------------------- Motif ACTTCCKG MEME-3 Description -------------------------------------------------------------------------------- Simplified A 61::::11 pos.-specific C 27::aa:: probability G 2:::::47 matrix T :1aa::51 bits 2.1 ** 1.9 **** 1.7 **** 1.4 **** Relative 1.2 **** Entropy 1.0 **** (10.6 bits) 0.8 ***** * 0.6 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel ACTTCCTG consensus G G sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ACTTCCKG MEME-3 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr20:61958493-61958573 62 1.69e-05 CGGCCCGGGG ACTTCCTG TTGACCGCTC chrX:8723333-8723413 36 1.69e-05 cttgctagta acttcctg ccacctagga chr2:25640817-25640897 48 1.69e-05 gatgcgtgtc acttcctg gaagaagcat chr10:50543663-50543743 54 1.69e-05 TCTCTTGACT ACTTCCTG TGGGTCCTGA chr3:13711956-13712036 62 1.69e-05 cctgggctgt acttcctg ctttgtgctg chr8:140495754-140495834 67 1.69e-05 ctctccacgc acttcctg tctatt chr16:86295143-86295223 65 1.69e-05 gtgatgtgtc acttcctg gtcAATGC chr16:86245591-86245671 59 1.69e-05 CTGGGACGGG ACTTCCTG TTTTGTTTGG chr5:178587769-178587849 25 1.69e-05 ggggaggtgc acttcctg ttcccatcat chr7:132242542-132242622 42 1.69e-05 GCTACTTCCC ACTTCCTG TAGATCCGCA chr16:5566305-5566385 63 1.69e-05 gtcttccatc acttcctG TCTCACATTA chr16:86945047-86945127 73 1.69e-05 CCTGTTTCCT ACTTCCTG chr12:115587742-11558782 37 1.69e-05 gtaaacatag acttcctg tgtgtaccgg chr1:220906484-220906564 45 3.30e-05 GTTTCCTTTC ACTTCCGG TTAGAACCAG chr12:127944432-12794451 20 3.30e-05 CCTGGGCGGG ACTTCCGG GAATTCCCAT chr19:6953125-6953205 47 3.30e-05 aggagcggta acttccgg gtcattgcca chr6:51928493-51928573 30 3.30e-05 caccaccacc acttccgg tctaacagcc chr18:61157733-61157813 63 3.30e-05 GGAGGGATAC ACTTCCGG GGCAAGGGAG chr19:46456630-46456710 44 3.30e-05 CACTGAGGTC ACTTCCGG TGATAGCAGG chr4:6179672-6179752 46 3.30e-05 ATCCGGCTTC ACTTCCGG CTGCAGGCTT chr8:64304073-64304153 42 5.07e-05 AGCATCCGCA GCTTCCTG TATTCTGAGC chr4:18077624-18077704 51 5.07e-05 cttctgatca gcttcctg ttcacgtgag chr6:58287732-58287812 48 5.07e-05 AGGGACTGCG GCTTCCTG CGCAGCGCCC chr14:76618068-76618148 57 5.07e-05 CCATCTCCTG GCTTCCTG TGGCTCCGCC chr20:43858254-43858334 42 5.07e-05 TCACGTGGTT GCTTCCTG GAAGTGAAAG chr19:21105980-21106060 58 8.30e-05 GGATAGGGCG GCTTCCGG GATGTGGCGG chr19:21541698-21541778 69 8.30e-05 GGAGAGGACG GCTTCCGG GATG chr6:168091419-168091499 27 8.30e-05 tcccgccttt gcttccgg ttgtcccacc chr2:356516-356596 43 8.30e-05 CCTACTTGCC GCTTCCGG TGTCACGACT chr16:3481922-3482002 43 8.30e-05 TCGGCTCGTG GCTTCCGG TTCCTCACCA chr19:51402978-51403058 51 8.30e-05 aagagcagta acttccag gtcattggca chr19:57276640-57276720 55 8.30e-05 GCGTATTTCC GCTTCCGG TGGCGTTTTA chr6:170475575-170475655 24 8.30e-05 CAATCGTCTC ACTTCCAG AAACGATTCT chr19:36822613-36822693 48 8.30e-05 GGGAGGGCGG GCTTCCGG AAACGGCGGC chr2:180446439-180446519 70 8.30e-05 agaagtgata acttccag gtc chr15:90000481-90000561 16 1.01e-04 aaaagggctt ccttcctg gagcctgact chr6:169295357-169295437 19 1.01e-04 CGGTTATTTC CCTTCCTG TTTGTCTGCC chr17:63382001-63382081 67 1.01e-04 AAGCCCAGCC CCTTCCTG CTGAGG chr7:4699329-4699409 52 1.01e-04 agaatttcct ccttcctg tttctcccct chr8:3442532-3442612 66 1.36e-04 CCCTCCCTCC CCTTCCGG TGGGGCG chr1:244427627-244427707 50 1.36e-04 TGGGGAAACT CCTTCCGG ATAGAAACCA chr1:5409009-5409089 62 1.36e-04 TGTTGACGTC ACTTCCTT CCTCAGTAAG chr2:149838048-149838128 56 1.36e-04 AGGGGGTGGG ACTTCCTT GGCTGCCGTT chr19:9517707-9517787 59 1.70e-04 CCGGGAGCGC ACTTCCGT TTCCAGGCAT chr10:4375777-4375857 61 1.70e-04 TCTGTGACtt acttccgt tttttctacc chr13:48478577-48478657 62 1.70e-04 tctgtacctc acttccgt tttctgtacc chr2:101356348-101356428 53 1.70e-04 gaagaccgta acttccgt cttgccagcc chr10:4376481-4376561 64 1.70e-04 tccataactc acttccgt ttcctgtga chr3:170241121-170241201 11 2.03e-04 catttccatc acttccta gctttctgtc chr10:132886956-13288703 29 2.03e-04 CGCTGACGTC ATTTCCGG TGTCCCTGTG chr6:168476477-168476557 64 2.03e-04 CCGTGTCCAC ATTTCCGG TGCCCGGTG chr12:107987630-10798771 55 2.03e-04 acttcccctc acttccta ttggccagca chr19:57742273-57742353 61 2.34e-04 TATTGGGCGC ACTTCCGA TGGCGTCAGG chr16:79444052-79444132 30 2.34e-04 tccgtacctc acttccga tttctgtacg chr19:40562081-40562161 58 2.65e-04 TGGAACCGCT AATTCCGG TGCGGTGGCC chr5:21459515-21459595 65 3.34e-04 TGGAGGCGGT ACTTCCTC CAGCATTT chr11:124994188-12499426 2 3.34e-04 G ACTTCCTC TGGACTTTCC chr16:8438840-8438920 9 3.34e-04 gaatccca gcttcctt taagatccca chr8:17549751-17549831 7 3.34e-04 agcctc ccttccag gtcgagtcat chr10:49407755-49407835 55 3.34e-04 TCGTTACACT ACTTCctc ttcctgggca chr1:237392797-237392877 14 3.34e-04 AACATCCCAG AGTTCCTG TTGGTACATT chr11:123349168-12334924 56 3.34e-04 GAAAGGAGGC AGTTCCTG GTTCCGGTTC chr7:6865935-6866015 72 3.52e-04 CTTGTTGTCT GTTTCCTG G chr19:52956744-52956824 63 3.52e-04 CGCAAGCGCA GTTTCCTG AAGACCCGGA chr5:126560262-126560342 20 4.18e-04 tgatagatct gcttccgt tccggtgaac chr21:39748284-39748364 18 4.18e-04 CTCTCCCACC ACTTCCGC TCTCTTTCAC chr16:50685918-50685998 24 4.18e-04 catcatatta acttccat cccattggcc chr1:19007937-19008017 62 4.68e-04 ACACAGTACC ATTTCCAG CAGTACTACT chr3:44754055-44754135 18 4.68e-04 TGTTCCTCCC GCTTCCTA GAGAATCAGA chr19:37808732-37808812 35 4.68e-04 ATTGGTCGCC GTTTCCGG AAGCCCGCCC chr19:37742713-37742793 68 4.68e-04 CCGCCCCCAC GTTTCCGG GAGCC chr17:72355088-72355168 42 5.53e-04 gtcttatccc ctttcctg ttgcctggaa chr11:45615672-45615752 67 6.01e-04 aagagggctc aattccag gacttt chr3:10739824-10739904 34 6.01e-04 cacgtgaccc aattccag ccaatgagac chr1:217804470-217804550 21 6.54e-04 ACTGCTTTCC CCTTCCTA TAATCCCCTC chr7:127903588-127903668 12 6.54e-04 aaagagctct ccttccta aatgttccgg chr5:140420832-140420912 58 6.54e-04 GGCCAGAGAG ATTTCCTT TACATGACAG chr16:85995918-85995998 70 6.71e-04 gtcacatgtc cattcctg aac chr10:75011880-75011960 6 6.71e-04 CAATC CATTCCTG TCAATCCAGT chr20:39541999-39542079 69 7.89e-04 GTCCAGAAGT CATTCCGG ACTC chr21:32862957-32863037 57 9.03e-04 tagactgggg agttccag gaaggattct chr11:6846697-6846777 11 9.03e-04 tctgcttgtt aattccgt ccctgtttct chr3:11017639-11017719 33 9.03e-04 CAGcatcaag agttccag gatttatttt chr20:54747785-54747865 63 9.03e-04 tctgtacgtc atttccga tttctgtacg chr19:20844415-20844495 23 9.34e-04 TGATTGGATG GTTTCCAG CCCACCATCC -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ACTTCCKG MEME-3 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr20:61958493-61958573 1.7e-05 61_[+3]_11 chrX:8723333-8723413 1.7e-05 35_[+3]_37 chr2:25640817-25640897 1.7e-05 47_[+3]_25 chr10:50543663-50543743 1.7e-05 53_[+3]_19 chr3:13711956-13712036 1.7e-05 61_[+3]_11 chr8:140495754-140495834 1.7e-05 66_[+3]_6 chr16:86295143-86295223 1.7e-05 64_[+3]_8 chr16:86245591-86245671 1.7e-05 58_[+3]_14 chr5:178587769-178587849 1.7e-05 24_[+3]_48 chr7:132242542-132242622 1.7e-05 41_[+3]_31 chr16:5566305-5566385 1.7e-05 62_[+3]_10 chr16:86945047-86945127 1.7e-05 72_[+3] chr12:115587742-11558782 1.7e-05 36_[+3]_36 chr1:220906484-220906564 3.3e-05 44_[+3]_28 chr12:127944432-12794451 3.3e-05 19_[+3]_53 chr19:6953125-6953205 3.3e-05 46_[+3]_26 chr6:51928493-51928573 3.3e-05 29_[+3]_43 chr18:61157733-61157813 3.3e-05 62_[+3]_10 chr19:46456630-46456710 3.3e-05 43_[+3]_29 chr4:6179672-6179752 3.3e-05 45_[+3]_27 chr8:64304073-64304153 5.1e-05 41_[+3]_31 chr4:18077624-18077704 5.1e-05 50_[+3]_22 chr6:58287732-58287812 5.1e-05 47_[+3]_25 chr14:76618068-76618148 5.1e-05 56_[+3]_16 chr20:43858254-43858334 5.1e-05 41_[+3]_31 chr19:21105980-21106060 8.3e-05 57_[+3]_15 chr19:21541698-21541778 8.3e-05 68_[+3]_4 chr6:168091419-168091499 8.3e-05 26_[+3]_46 chr2:356516-356596 8.3e-05 42_[+3]_30 chr16:3481922-3482002 8.3e-05 42_[+3]_30 chr19:51402978-51403058 8.3e-05 50_[+3]_22 chr19:57276640-57276720 8.3e-05 54_[+3]_18 chr6:170475575-170475655 8.3e-05 23_[+3]_49 chr19:36822613-36822693 8.3e-05 47_[+3]_25 chr2:180446439-180446519 8.3e-05 69_[+3]_3 chr15:90000481-90000561 0.0001 15_[+3]_57 chr6:169295357-169295437 0.0001 18_[+3]_54 chr17:63382001-63382081 0.0001 66_[+3]_6 chr7:4699329-4699409 0.0001 51_[+3]_21 chr8:3442532-3442612 0.00014 65_[+3]_7 chr1:244427627-244427707 0.00014 49_[+3]_23 chr1:5409009-5409089 0.00014 61_[+3]_11 chr2:149838048-149838128 0.00014 55_[+3]_17 chr19:9517707-9517787 0.00017 58_[+3]_14 chr10:4375777-4375857 0.00017 60_[+3]_12 chr13:48478577-48478657 0.00017 61_[+3]_11 chr2:101356348-101356428 0.00017 52_[+3]_20 chr10:4376481-4376561 0.00017 63_[+3]_9 chr3:170241121-170241201 0.0002 10_[+3]_62 chr10:132886956-13288703 0.0002 28_[+3]_44 chr6:168476477-168476557 0.0002 63_[+3]_9 chr12:107987630-10798771 0.0002 54_[+3]_18 chr19:57742273-57742353 0.00023 60_[+3]_12 chr16:79444052-79444132 0.00023 29_[+3]_43 chr19:40562081-40562161 0.00027 57_[+3]_15 chr5:21459515-21459595 0.00033 64_[+3]_8 chr11:124994188-12499426 0.00033 1_[+3]_71 chr16:8438840-8438920 0.00033 8_[+3]_64 chr8:17549751-17549831 0.00033 6_[+3]_66 chr10:49407755-49407835 0.00033 54_[+3]_18 chr1:237392797-237392877 0.00033 13_[+3]_59 chr11:123349168-12334924 0.00033 55_[+3]_17 chr7:6865935-6866015 0.00035 71_[+3]_1 chr19:52956744-52956824 0.00035 62_[+3]_10 chr5:126560262-126560342 0.00042 19_[+3]_53 chr21:39748284-39748364 0.00042 17_[+3]_55 chr16:50685918-50685998 0.00042 23_[+3]_49 chr1:19007937-19008017 0.00047 61_[+3]_11 chr3:44754055-44754135 0.00047 17_[+3]_55 chr19:37808732-37808812 0.00047 34_[+3]_38 chr19:37742713-37742793 0.00047 67_[+3]_5 chr17:72355088-72355168 0.00055 41_[+3]_31 chr11:45615672-45615752 0.0006 66_[+3]_6 chr3:10739824-10739904 0.0006 33_[+3]_39 chr1:217804470-217804550 0.00065 20_[+3]_52 chr7:127903588-127903668 0.00065 11_[+3]_61 chr5:140420832-140420912 0.00065 57_[+3]_15 chr16:85995918-85995998 0.00067 69_[+3]_3 chr10:75011880-75011960 0.00067 5_[+3]_67 chr20:39541999-39542079 0.00079 68_[+3]_4 chr21:32862957-32863037 0.0009 56_[+3]_16 chr11:6846697-6846777 0.0009 10_[+3]_62 chr3:11017639-11017719 0.0009 32_[+3]_40 chr20:54747785-54747865 0.0009 62_[+3]_10 chr19:20844415-20844495 0.00093 22_[+3]_50 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ACTTCCKG MEME-3 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF ACTTCCKG width=8 seqs=85 chr20:61958493-61958573 ( 62) ACTTCCTG 1 chrX:8723333-8723413 ( 36) ACTTCCTG 1 chr2:25640817-25640897 ( 48) ACTTCCTG 1 chr10:50543663-50543743 ( 54) ACTTCCTG 1 chr3:13711956-13712036 ( 62) ACTTCCTG 1 chr8:140495754-140495834 ( 67) ACTTCCTG 1 chr16:86295143-86295223 ( 65) ACTTCCTG 1 chr16:86245591-86245671 ( 59) ACTTCCTG 1 chr5:178587769-178587849 ( 25) ACTTCCTG 1 chr7:132242542-132242622 ( 42) ACTTCCTG 1 chr16:5566305-5566385 ( 63) ACTTCCTG 1 chr16:86945047-86945127 ( 73) ACTTCCTG 1 chr12:115587742-11558782 ( 37) ACTTCCTG 1 chr1:220906484-220906564 ( 45) ACTTCCGG 1 chr12:127944432-12794451 ( 20) ACTTCCGG 1 chr19:6953125-6953205 ( 47) ACTTCCGG 1 chr6:51928493-51928573 ( 30) ACTTCCGG 1 chr18:61157733-61157813 ( 63) ACTTCCGG 1 chr19:46456630-46456710 ( 44) ACTTCCGG 1 chr4:6179672-6179752 ( 46) ACTTCCGG 1 chr8:64304073-64304153 ( 42) GCTTCCTG 1 chr4:18077624-18077704 ( 51) GCTTCCTG 1 chr6:58287732-58287812 ( 48) GCTTCCTG 1 chr14:76618068-76618148 ( 57) GCTTCCTG 1 chr20:43858254-43858334 ( 42) GCTTCCTG 1 chr19:21105980-21106060 ( 58) GCTTCCGG 1 chr19:21541698-21541778 ( 69) GCTTCCGG 1 chr6:168091419-168091499 ( 27) GCTTCCGG 1 chr2:356516-356596 ( 43) GCTTCCGG 1 chr16:3481922-3482002 ( 43) GCTTCCGG 1 chr19:51402978-51403058 ( 51) ACTTCCAG 1 chr19:57276640-57276720 ( 55) GCTTCCGG 1 chr6:170475575-170475655 ( 24) ACTTCCAG 1 chr19:36822613-36822693 ( 48) GCTTCCGG 1 chr2:180446439-180446519 ( 70) ACTTCCAG 1 chr15:90000481-90000561 ( 16) CCTTCCTG 1 chr6:169295357-169295437 ( 19) CCTTCCTG 1 chr17:63382001-63382081 ( 67) CCTTCCTG 1 chr7:4699329-4699409 ( 52) CCTTCCTG 1 chr8:3442532-3442612 ( 66) CCTTCCGG 1 chr1:244427627-244427707 ( 50) CCTTCCGG 1 chr1:5409009-5409089 ( 62) ACTTCCTT 1 chr2:149838048-149838128 ( 56) ACTTCCTT 1 chr19:9517707-9517787 ( 59) ACTTCCGT 1 chr10:4375777-4375857 ( 61) ACTTCCGT 1 chr13:48478577-48478657 ( 62) ACTTCCGT 1 chr2:101356348-101356428 ( 53) ACTTCCGT 1 chr10:4376481-4376561 ( 64) ACTTCCGT 1 chr3:170241121-170241201 ( 11) ACTTCCTA 1 chr10:132886956-13288703 ( 29) ATTTCCGG 1 chr6:168476477-168476557 ( 64) ATTTCCGG 1 chr12:107987630-10798771 ( 55) ACTTCCTA 1 chr19:57742273-57742353 ( 61) ACTTCCGA 1 chr16:79444052-79444132 ( 30) ACTTCCGA 1 chr19:40562081-40562161 ( 58) AATTCCGG 1 chr5:21459515-21459595 ( 65) ACTTCCTC 1 chr11:124994188-12499426 ( 2) ACTTCCTC 1 chr16:8438840-8438920 ( 9) GCTTCCTT 1 chr8:17549751-17549831 ( 7) CCTTCCAG 1 chr10:49407755-49407835 ( 55) ACTTCCTC 1 chr1:237392797-237392877 ( 14) AGTTCCTG 1 chr11:123349168-12334924 ( 56) AGTTCCTG 1 chr7:6865935-6866015 ( 72) GTTTCCTG 1 chr19:52956744-52956824 ( 63) GTTTCCTG 1 chr5:126560262-126560342 ( 20) GCTTCCGT 1 chr21:39748284-39748364 ( 18) ACTTCCGC 1 chr16:50685918-50685998 ( 24) ACTTCCAT 1 chr1:19007937-19008017 ( 62) ATTTCCAG 1 chr3:44754055-44754135 ( 18) GCTTCCTA 1 chr19:37808732-37808812 ( 35) GTTTCCGG 1 chr19:37742713-37742793 ( 68) GTTTCCGG 1 chr17:72355088-72355168 ( 42) CTTTCCTG 1 chr11:45615672-45615752 ( 67) AATTCCAG 1 chr3:10739824-10739904 ( 34) AATTCCAG 1 chr1:217804470-217804550 ( 21) CCTTCCTA 1 chr7:127903588-127903668 ( 12) CCTTCCTA 1 chr5:140420832-140420912 ( 58) ATTTCCTT 1 chr16:85995918-85995998 ( 70) CATTCCTG 1 chr10:75011880-75011960 ( 6) CATTCCTG 1 chr20:39541999-39542079 ( 69) CATTCCGG 1 chr21:32862957-32863037 ( 57) AGTTCCAG 1 chr11:6846697-6846777 ( 11) AATTCCGT 1 chr3:11017639-11017719 ( 33) AGTTCCAG 1 chr20:54747785-54747865 ( 63) ATTTCCGA 1 chr19:20844415-20844495 ( 23) GTTTCCAG 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ACTTCCKG MEME-3 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 8.05851 E= 3.3e-025 136 -72 -8 -1305 -153 155 -240 -100 -1305 -1305 -1305 195 -1305 -1305 -1305 195 -1305 198 -1305 -1305 -1305 198 -1305 -1305 -88 -1305 64 89 -134 -242 152 -88 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ACTTCCKG MEME-3 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 85 E= 3.3e-025 0.611765 0.152941 0.235294 0.000000 0.082353 0.741176 0.047059 0.129412 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.129412 0.000000 0.388235 0.482353 0.094118 0.047059 0.717647 0.141176 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ACTTCCKG MEME-3 regular expression -------------------------------------------------------------------------------- [AG]CTTCC[TG]G -------------------------------------------------------------------------------- Time 12.12 secs. ******************************************************************************** ******************************************************************************** MOTIF RCCAATSA MEME-4 width = 8 sites = 62 llr = 503 E-value = 4.1e-024 ******************************************************************************** -------------------------------------------------------------------------------- Motif RCCAATSA MEME-4 Description -------------------------------------------------------------------------------- Simplified A 4::aa::7 pos.-specific C :aa:::61 probability G 5:::::32 matrix T 1::::a1: bits 2.1 ** 1.9 ***** 1.7 ***** 1.4 ***** Relative 1.2 ***** Entropy 1.0 ***** (11.7 bits) 0.8 ***** * 0.6 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel GCCAATCA consensus A GG sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif RCCAATSA MEME-4 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr22:47666361-47666441 55 1.41e-05 tctagaactg gccaatca gaCTTCATAG chr12:130991548-13099162 39 1.41e-05 cacaggtctg gccaatca gtgtaatctc chr19:7220021-7220101 55 1.41e-05 cttcccctga gccaaTCA TAAGAGTCTG chr2:240832675-240832755 73 1.41e-05 ccacctctga gccaatca chr4:6410184-6410264 8 1.41e-05 GAACTGA GCCAATCA TCTTTCTCTC chr12:132999960-13300004 60 1.41e-05 TCATCACTGA GCCAATCA CGGTGTCCAG chr1:33704106-33704186 48 1.41e-05 ttgcacctca gccaaTCA ATGCAGCTAG chr2:42068077-42068157 9 1.41e-05 CAGCAACA GCCAATCA GAAACTCGCT chr20:49609754-49609834 42 1.41e-05 ccaaggcctg gccaatca gagcactgcc chr12:113399100-11339918 7 1.41e-05 ACCCCA GCCAATCA GTTCCTCCTC chr16:49958144-49958224 3 2.76e-05 ga accaatca ccaaggctaa chr19:2375538-2375618 52 2.76e-05 TCCAGTGTGG ACCAATCA CTGGCTGGAG chr11:45615672-45615752 44 2.76e-05 ccctgactga accaatca gagccaagag chr19:17131814-17131894 33 2.76e-05 cccaaaatga accaatca gcataggcct chr8:49419870-49419950 57 2.76e-05 tgtaaaacgg accaatca gcgctcggta chr8:142583645-142583725 55 2.76e-05 ccctcatgca accaatca gactggttgt chr16:8438840-8438920 60 2.76e-05 tcacccctaa accaatca agagcaaagg chr15:80792030-80792110 9 2.76e-05 gtcttggg accaatca ctatagacaa chr21:33406912-33406992 49 2.76e-05 tcacttcaag accaatca ctaatcaaaa chr16:84277506-84277586 70 2.76e-05 GCtgagatga accaatca aat chr10:119656186-11965626 66 2.76e-05 caatctttga accaatca ctgtggc chr19:13755587-13755667 43 4.16e-05 ccacctctga gccaatga aggtagatgg chr20:36857042-36857122 68 4.16e-05 gacatttctg gccaatga tatgt chr2:25640817-25640897 16 4.16e-05 atttgctctg gccaatga aatggagagg chr8:17549751-17549831 39 4.16e-05 ctaagacccg gccaatga gacggaagct chr19:8754986-8755066 49 4.16e-05 cacacccaga gccaatga gaggcaagga chr5:178587769-178587849 71 4.16e-05 actagctctg gccaatga gc chr1:19318258-19318338 57 4.16e-05 agcaggcaca gccaatga gacttcattt chr12:132076987-13207706 44 5.49e-05 ctcagctaag accaatga gatgcaagga chr19:21579796-21579876 54 8.44e-05 TTAAACCGTA TCCAATCA GACACGCAGA chr19:21105980-21106060 24 8.44e-05 CTGGGAACCG TCCAATCA GGAACGCAGC chr19:21541698-21541778 6 8.44e-05 CGTTA TCCAATCA GCGACGCTGG chr19:21182656-21182736 1 8.44e-05 . TCCAATCA GGGTGCTGGG chr2:601090-601170 48 8.44e-05 GGTGATCTGG TCCAATCA GAGGCCTGCA chr10:30368527-30368607 24 8.44e-05 ttcaccaggc tccaatca gctgaggggg chr16:8561604-8561684 42 1.13e-04 TTAAAACTGA GCCAATTA TAGGACGTCC chr15:69818058-69818138 55 1.13e-04 ctcatttctg gccaatta cacctaaggg chr7:100825924-100826004 55 1.41e-04 AGCTCACTGG GCCAATGG AAAGCCATCT chr12:131978149-13197822 11 1.41e-04 TTGTTCCCTG GCCAATGG GAAAGGCTCT chr11:45275371-45275451 47 1.41e-04 ctgagctacg gccaatgg gatgcaagcg chr21:18715541-18715621 63 1.41e-04 AATTCAGGGC ACCAATTA GCATGCTGAG chr16:86295143-86295223 34 1.41e-04 actagttctg gccaatgg ggtttgtgga chr19:36822613-36822693 64 1.41e-04 GGAAACGGCG GCCAATGG GAAACGTGA chr2:180446439-180446519 43 1.41e-04 ctgggttctg gccaatgg gatatgagta chr17:71848258-71848338 21 1.57e-04 GTTGGGATTG GCCAATCC TGTCACCTCA chr21:44612406-44612486 73 1.57e-04 CAGAGCTTCC GCCAATCC chr17:7909360-7909440 16 1.85e-04 ATTAGAATCA ACCAATGG TCAGAGAGGA chr21:32862957-32863037 25 1.85e-04 ctcagctgcc accaatgg aacaagacag chr21:37522659-37522739 56 1.99e-04 TTTGTCTCTA ACCAATCC TTTTTGGATA chr16:79444052-79444132 6 1.99e-04 ctgta accaatcc agccgttccg chr20:54747785-54747865 19 1.99e-04 ccaagctgta accaatcc agccgttctg chr1:37889607-37889687 48 2.59e-04 catcagctga gccaattg aatgtcttct chr6:168091419-168091499 57 2.59e-04 tccggaccaa accaatgc tcatcttgca chr16:19165366-19165446 58 2.59e-04 cacaggctgg gccaattg cagtgctaca chr20:60000900-60000980 31 2.59e-04 GGGCAGAATG GCCAATTG CAGGACGTTC chr3:2895578-2895658 34 2.89e-04 TTCCCCAAAA ACCAATTG ACGAAGCATT chr3:13711956-13712036 14 3.32e-04 catgagacaa gccaataa gcatggatcc chr19:51465632-51465712 26 3.32e-04 TGGTTCTTCA TCCAATGG TCCACCTCCA chr20:61958493-61958573 29 3.90e-04 ACTTGTGTTT ACCACTCA GGGACTTCCT chr4:6179672-6179752 3 3.90e-04 TA ACCACTCA ATCTCACGCT chr6:51928493-51928573 45 4.18e-04 cggtctaaca gccaaaca tgtttctaca chr10:4446038-4446118 63 4.63e-04 aggaagctat gcccatca gagaaaacta -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif RCCAATSA MEME-4 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr22:47666361-47666441 1.4e-05 54_[+4]_18 chr12:130991548-13099162 1.4e-05 38_[+4]_34 chr19:7220021-7220101 1.4e-05 54_[+4]_18 chr2:240832675-240832755 1.4e-05 72_[+4] chr4:6410184-6410264 1.4e-05 7_[+4]_65 chr12:132999960-13300004 1.4e-05 59_[+4]_13 chr1:33704106-33704186 1.4e-05 47_[+4]_25 chr2:42068077-42068157 1.4e-05 8_[+4]_64 chr20:49609754-49609834 1.4e-05 41_[+4]_31 chr12:113399100-11339918 1.4e-05 6_[+4]_66 chr16:49958144-49958224 2.8e-05 2_[+4]_70 chr19:2375538-2375618 2.8e-05 51_[+4]_21 chr11:45615672-45615752 2.8e-05 43_[+4]_29 chr19:17131814-17131894 2.8e-05 32_[+4]_40 chr8:49419870-49419950 2.8e-05 56_[+4]_16 chr8:142583645-142583725 2.8e-05 54_[+4]_18 chr16:8438840-8438920 2.8e-05 59_[+4]_13 chr15:80792030-80792110 2.8e-05 8_[+4]_64 chr21:33406912-33406992 2.8e-05 48_[+4]_24 chr16:84277506-84277586 2.8e-05 69_[+4]_3 chr10:119656186-11965626 2.8e-05 65_[+4]_7 chr19:13755587-13755667 4.2e-05 42_[+4]_30 chr20:36857042-36857122 4.2e-05 67_[+4]_5 chr2:25640817-25640897 4.2e-05 15_[+4]_57 chr8:17549751-17549831 4.2e-05 38_[+4]_34 chr19:8754986-8755066 4.2e-05 48_[+4]_24 chr5:178587769-178587849 4.2e-05 70_[+4]_2 chr1:19318258-19318338 4.2e-05 56_[+4]_16 chr12:132076987-13207706 5.5e-05 43_[+4]_29 chr19:21579796-21579876 8.4e-05 53_[+4]_19 chr19:21105980-21106060 8.4e-05 23_[+4]_49 chr19:21541698-21541778 8.4e-05 5_[+4]_67 chr19:21182656-21182736 8.4e-05 [+4]_72 chr2:601090-601170 8.4e-05 47_[+4]_25 chr10:30368527-30368607 8.4e-05 23_[+4]_49 chr16:8561604-8561684 0.00011 41_[+4]_31 chr15:69818058-69818138 0.00011 54_[+4]_18 chr7:100825924-100826004 0.00014 54_[+4]_18 chr12:131978149-13197822 0.00014 10_[+4]_62 chr11:45275371-45275451 0.00014 46_[+4]_26 chr21:18715541-18715621 0.00014 62_[+4]_10 chr16:86295143-86295223 0.00014 33_[+4]_39 chr19:36822613-36822693 0.00014 63_[+4]_9 chr2:180446439-180446519 0.00014 42_[+4]_30 chr17:71848258-71848338 0.00016 20_[+4]_52 chr21:44612406-44612486 0.00016 72_[+4] chr17:7909360-7909440 0.00018 15_[+4]_57 chr21:32862957-32863037 0.00018 24_[+4]_48 chr21:37522659-37522739 0.0002 55_[+4]_17 chr16:79444052-79444132 0.0002 5_[+4]_67 chr20:54747785-54747865 0.0002 18_[+4]_54 chr1:37889607-37889687 0.00026 47_[+4]_25 chr6:168091419-168091499 0.00026 56_[+4]_16 chr16:19165366-19165446 0.00026 57_[+4]_15 chr20:60000900-60000980 0.00026 30_[+4]_42 chr3:2895578-2895658 0.00029 33_[+4]_39 chr3:13711956-13712036 0.00033 13_[+4]_59 chr19:51465632-51465712 0.00033 25_[+4]_47 chr20:61958493-61958573 0.00039 28_[+4]_44 chr4:6179672-6179752 0.00039 2_[+4]_70 chr6:51928493-51928573 0.00042 44_[+4]_28 chr10:4446038-4446118 0.00046 62_[+4]_10 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif RCCAATSA MEME-4 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF RCCAATSA width=8 seqs=62 chr22:47666361-47666441 ( 55) GCCAATCA 1 chr12:130991548-13099162 ( 39) GCCAATCA 1 chr19:7220021-7220101 ( 55) GCCAATCA 1 chr2:240832675-240832755 ( 73) GCCAATCA 1 chr4:6410184-6410264 ( 8) GCCAATCA 1 chr12:132999960-13300004 ( 60) GCCAATCA 1 chr1:33704106-33704186 ( 48) GCCAATCA 1 chr2:42068077-42068157 ( 9) GCCAATCA 1 chr20:49609754-49609834 ( 42) GCCAATCA 1 chr12:113399100-11339918 ( 7) GCCAATCA 1 chr16:49958144-49958224 ( 3) ACCAATCA 1 chr19:2375538-2375618 ( 52) ACCAATCA 1 chr11:45615672-45615752 ( 44) ACCAATCA 1 chr19:17131814-17131894 ( 33) ACCAATCA 1 chr8:49419870-49419950 ( 57) ACCAATCA 1 chr8:142583645-142583725 ( 55) ACCAATCA 1 chr16:8438840-8438920 ( 60) ACCAATCA 1 chr15:80792030-80792110 ( 9) ACCAATCA 1 chr21:33406912-33406992 ( 49) ACCAATCA 1 chr16:84277506-84277586 ( 70) ACCAATCA 1 chr10:119656186-11965626 ( 66) ACCAATCA 1 chr19:13755587-13755667 ( 43) GCCAATGA 1 chr20:36857042-36857122 ( 68) GCCAATGA 1 chr2:25640817-25640897 ( 16) GCCAATGA 1 chr8:17549751-17549831 ( 39) GCCAATGA 1 chr19:8754986-8755066 ( 49) GCCAATGA 1 chr5:178587769-178587849 ( 71) GCCAATGA 1 chr1:19318258-19318338 ( 57) GCCAATGA 1 chr12:132076987-13207706 ( 44) ACCAATGA 1 chr19:21579796-21579876 ( 54) TCCAATCA 1 chr19:21105980-21106060 ( 24) TCCAATCA 1 chr19:21541698-21541778 ( 6) TCCAATCA 1 chr19:21182656-21182736 ( 1) TCCAATCA 1 chr2:601090-601170 ( 48) TCCAATCA 1 chr10:30368527-30368607 ( 24) TCCAATCA 1 chr16:8561604-8561684 ( 42) GCCAATTA 1 chr15:69818058-69818138 ( 55) GCCAATTA 1 chr7:100825924-100826004 ( 55) GCCAATGG 1 chr12:131978149-13197822 ( 11) GCCAATGG 1 chr11:45275371-45275451 ( 47) GCCAATGG 1 chr21:18715541-18715621 ( 63) ACCAATTA 1 chr16:86295143-86295223 ( 34) GCCAATGG 1 chr19:36822613-36822693 ( 64) GCCAATGG 1 chr2:180446439-180446519 ( 43) GCCAATGG 1 chr17:71848258-71848338 ( 21) GCCAATCC 1 chr21:44612406-44612486 ( 73) GCCAATCC 1 chr17:7909360-7909440 ( 16) ACCAATGG 1 chr21:32862957-32863037 ( 25) ACCAATGG 1 chr21:37522659-37522739 ( 56) ACCAATCC 1 chr16:79444052-79444132 ( 6) ACCAATCC 1 chr20:54747785-54747865 ( 19) ACCAATCC 1 chr1:37889607-37889687 ( 48) GCCAATTG 1 chr6:168091419-168091499 ( 57) ACCAATGC 1 chr16:19165366-19165446 ( 58) GCCAATTG 1 chr20:60000900-60000980 ( 31) GCCAATTG 1 chr3:2895578-2895658 ( 34) ACCAATTG 1 chr3:13711956-13712036 ( 14) GCCAATAA 1 chr19:51465632-51465712 ( 26) TCCAATGG 1 chr20:61958493-61958573 ( 29) ACCACTCA 1 chr4:6179672-6179752 ( 3) ACCACTCA 1 chr6:51928493-51928573 ( 45) GCCAAACA 1 chr10:4446038-4446118 ( 63) GCCCATCA 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif RCCAATSA MEME-4 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 8.15962 E= 4.1e-024 57 -1260 109 -120 -1260 198 -1260 -1260 -1260 198 -1260 -1260 205 -397 -1260 -1260 202 -297 -1260 -1260 -388 -1260 -1260 192 -388 120 22 -120 154 -138 -25 -1260 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif RCCAATSA MEME-4 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 62 E= 4.1e-024 0.354839 0.000000 0.532258 0.112903 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.983871 0.016129 0.000000 0.000000 0.967742 0.032258 0.000000 0.000000 0.016129 0.000000 0.000000 0.983871 0.016129 0.580645 0.290323 0.112903 0.693548 0.096774 0.209677 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif RCCAATSA MEME-4 regular expression -------------------------------------------------------------------------------- [GA]CCAAT[CG][AG] -------------------------------------------------------------------------------- Time 15.54 secs. ******************************************************************************** ******************************************************************************** MOTIF GTCAYRTG MEME-5 width = 8 sites = 42 llr = 350 E-value = 1.3e-008 ******************************************************************************** -------------------------------------------------------------------------------- Motif GTCAYRTG MEME-5 Description -------------------------------------------------------------------------------- Simplified A 21:a:5:: pos.-specific C :1a:6::: probability G 8:::15:a matrix T :8::4:a: bits 2.1 ** * 1.9 ** ** 1.7 ** ** 1.4 ** ** Relative 1.2 * ** ** Entropy 1.0 **** *** (12.0 bits) 0.8 **** *** 0.6 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel GTCACGTG consensus A TA sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GTCAYRTG MEME-5 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr21:43594400-43594480 72 1.59e-05 tccagcctga gtcacgtg a chr16:49958144-49958224 53 3.11e-05 ccaggcccaa gtcacatg acggcctctg chr14:89498574-89498654 34 3.11e-05 gtcagaacca gtcacatg ccccacccat chr16:85995918-85995998 60 3.11e-05 tcagaactgg gtcacatg tccattcctg chr16:6737782-6737862 31 3.11e-05 gctagaacaa gtcacatg ggcccaacct chr10:133622565-13362264 22 3.11e-05 gccaaggcaa gtcacatg gccctactgc chr16:13228871-13228951 36 3.11e-05 gccaaagcaa gtcacatg actcaccttg chr15:70202231-70202311 31 3.11e-05 gctaagctca gtcacatg ACTGCTCAAA chr8:136685743-136685823 59 3.11e-05 ACAGCCTTCA GTCACATG CCCCAGCCAG chr16:50685918-50685998 49 3.11e-05 gccaaagcaa gtcacatg gccaagctca chr21:33406912-33406992 30 3.11e-05 ccagcaaggt gtcacatg ctcacttcaa chr12:105817868-10581794 29 3.11e-05 ctcagcctag gtcacatg acttgccctt chr10:119656186-11965626 47 3.11e-05 cctgtcataa gtcacatg tcaatctttg chr19:7220021-7220101 36 4.74e-05 cccagtctga gtcatgtg ccttcccctg chr11:15165601-15165681 21 4.74e-05 tggcacctaa gtcatgtg ttttactctt chr20:36857042-36857122 51 4.74e-05 gatggggagg gtcatgtg acatttctgg chr1:29839997-29840077 67 4.74e-05 ctcagattgg gtcatgtg ctcatg chr8:17549751-17549831 20 4.74e-05 tccaggtcga gtcatgtg actaagaccc chr16:8561604-8561684 64 4.74e-05 ACGTCCAACA GTcatgtg attaaaact chr3:11017639-11017719 67 4.74e-05 accagcttgg gtcatgtg ctcctc chr10:14420733-14420813 30 4.74e-05 cttggatcct gtcatgtg gtgtccgctt chr12:132999960-13300004 41 7.82e-05 GCTAGCTTGG ATCACGTG CTCATCACTG chr19:51497560-51497640 3 9.28e-05 at atcacatg actccaagta chr19:13755587-13755667 24 9.28e-05 cccagtccat atcacatg accacctctg chr7:127903588-127903668 68 9.28e-05 tctggcttga atcacatg tctat chr16:8438840-8438920 41 9.28e-05 tcagaactgc atcacatg ttcaccccta chr1:171283153-171283233 7 1.08e-04 GACGCT ATCATGTG CTTCCCATAG chr3:33532430-33532510 27 1.39e-04 AATGGGTCTG ATCATATG TGCCAAATTT chr3:10739824-10739904 22 1.39e-04 tttaggcatg gccacgtg acccaattcc chr6:157340155-157340235 35 1.39e-04 AAGGGGTGAT ATCATATG GCAGATTAGG chr16:67541356-67541436 16 1.39e-04 cacttctgct atcatatg tttcgttttt chr16:86295143-86295223 16 1.39e-04 ggtgacctgg gccacgtg actagttctg chr8:143799594-143799674 2 1.84e-04 G GACACGTG GCCCCAGtgg chr1:33704106-33704186 29 1.84e-04 ccaagcctag gtcaggtg cttgcacctc chr16:19165366-19165446 39 1.84e-04 cataggcacg gacacgtg acacaggctg chr15:80792030-80792110 63 1.84e-04 cccagggtgt gtcaggtg ctcagtcctc chr19:10114163-10114243 34 1.84e-04 AAGACCGGAA GTCAGGTG GTCAAAACCG chr1:19318258-19318338 36 1.84e-04 gttcagaaat gacacgtg accagcaggc chr1:171798099-171798179 5 2.13e-04 cttt gacacatg aggacgaatg chr21:44030005-44030085 42 2.29e-04 ggccacagca gccatgtg accgcaccca chr21:32862957-32863037 6 2.29e-04 ggctg gccatgtg actcagctgc chr16:21716208-21716288 47 2.29e-04 cgtggaccat gccatgtg gtgtccactt -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GTCAYRTG MEME-5 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr21:43594400-43594480 1.6e-05 71_[+5]_1 chr16:49958144-49958224 3.1e-05 52_[+5]_20 chr14:89498574-89498654 3.1e-05 33_[+5]_39 chr16:85995918-85995998 3.1e-05 59_[+5]_13 chr16:6737782-6737862 3.1e-05 30_[+5]_42 chr10:133622565-13362264 3.1e-05 21_[+5]_51 chr16:13228871-13228951 3.1e-05 35_[+5]_37 chr15:70202231-70202311 3.1e-05 30_[+5]_42 chr8:136685743-136685823 3.1e-05 58_[+5]_14 chr16:50685918-50685998 3.1e-05 48_[+5]_24 chr21:33406912-33406992 3.1e-05 29_[+5]_43 chr12:105817868-10581794 3.1e-05 28_[+5]_44 chr10:119656186-11965626 3.1e-05 46_[+5]_26 chr19:7220021-7220101 4.7e-05 35_[+5]_37 chr11:15165601-15165681 4.7e-05 20_[+5]_52 chr20:36857042-36857122 4.7e-05 50_[+5]_22 chr1:29839997-29840077 4.7e-05 66_[+5]_6 chr8:17549751-17549831 4.7e-05 19_[+5]_53 chr16:8561604-8561684 4.7e-05 63_[+5]_9 chr3:11017639-11017719 4.7e-05 66_[+5]_6 chr10:14420733-14420813 4.7e-05 29_[+5]_43 chr12:132999960-13300004 7.8e-05 40_[+5]_32 chr19:51497560-51497640 9.3e-05 2_[+5]_70 chr19:13755587-13755667 9.3e-05 23_[+5]_49 chr7:127903588-127903668 9.3e-05 67_[+5]_5 chr16:8438840-8438920 9.3e-05 40_[+5]_32 chr1:171283153-171283233 0.00011 6_[+5]_66 chr3:33532430-33532510 0.00014 26_[+5]_46 chr3:10739824-10739904 0.00014 21_[+5]_51 chr6:157340155-157340235 0.00014 34_[+5]_38 chr16:67541356-67541436 0.00014 15_[+5]_57 chr16:86295143-86295223 0.00014 15_[+5]_57 chr8:143799594-143799674 0.00018 1_[+5]_71 chr1:33704106-33704186 0.00018 28_[+5]_44 chr16:19165366-19165446 0.00018 38_[+5]_34 chr15:80792030-80792110 0.00018 62_[+5]_10 chr19:10114163-10114243 0.00018 33_[+5]_39 chr1:19318258-19318338 0.00018 35_[+5]_37 chr1:171798099-171798179 0.00021 4_[+5]_68 chr21:44030005-44030085 0.00023 41_[+5]_31 chr21:32862957-32863037 0.00023 5_[+5]_67 chr16:21716208-21716288 0.00023 46_[+5]_26 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GTCAYRTG MEME-5 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF GTCAYRTG width=8 seqs=42 chr21:43594400-43594480 ( 72) GTCACGTG 1 chr16:49958144-49958224 ( 53) GTCACATG 1 chr14:89498574-89498654 ( 34) GTCACATG 1 chr16:85995918-85995998 ( 60) GTCACATG 1 chr16:6737782-6737862 ( 31) GTCACATG 1 chr10:133622565-13362264 ( 22) GTCACATG 1 chr16:13228871-13228951 ( 36) GTCACATG 1 chr15:70202231-70202311 ( 31) GTCACATG 1 chr8:136685743-136685823 ( 59) GTCACATG 1 chr16:50685918-50685998 ( 49) GTCACATG 1 chr21:33406912-33406992 ( 30) GTCACATG 1 chr12:105817868-10581794 ( 29) GTCACATG 1 chr10:119656186-11965626 ( 47) GTCACATG 1 chr19:7220021-7220101 ( 36) GTCATGTG 1 chr11:15165601-15165681 ( 21) GTCATGTG 1 chr20:36857042-36857122 ( 51) GTCATGTG 1 chr1:29839997-29840077 ( 67) GTCATGTG 1 chr8:17549751-17549831 ( 20) GTCATGTG 1 chr16:8561604-8561684 ( 64) GTCATGTG 1 chr3:11017639-11017719 ( 67) GTCATGTG 1 chr10:14420733-14420813 ( 30) GTCATGTG 1 chr12:132999960-13300004 ( 41) ATCACGTG 1 chr19:51497560-51497640 ( 3) ATCACATG 1 chr19:13755587-13755667 ( 24) ATCACATG 1 chr7:127903588-127903668 ( 68) ATCACATG 1 chr16:8438840-8438920 ( 41) ATCACATG 1 chr1:171283153-171283233 ( 7) ATCATGTG 1 chr3:33532430-33532510 ( 27) ATCATATG 1 chr3:10739824-10739904 ( 22) GCCACGTG 1 chr6:157340155-157340235 ( 35) ATCATATG 1 chr16:67541356-67541436 ( 16) ATCATATG 1 chr16:86295143-86295223 ( 16) GCCACGTG 1 chr8:143799594-143799674 ( 2) GACACGTG 1 chr1:33704106-33704186 ( 29) GTCAGGTG 1 chr16:19165366-19165446 ( 39) GACACGTG 1 chr15:80792030-80792110 ( 63) GTCAGGTG 1 chr19:10114163-10114243 ( 34) GTCAGGTG 1 chr1:19318258-19318338 ( 36) GACACGTG 1 chr1:171798099-171798179 ( 5) GACACATG 1 chr21:44030005-44030085 ( 42) GCCATGTG 1 chr21:32862957-32863037 ( 6) GCCATGTG 1 chr16:21716208-21716288 ( 47) GCCATGTG 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GTCAYRTG MEME-5 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 9.74794 E= 1.3e-008 -15 -1204 166 -1204 -132 -109 -1204 160 -1204 198 -1204 -1204 207 -1204 -1204 -1204 -1204 118 -180 46 100 -1204 107 -1204 -1204 -1204 -1204 195 -1204 -1204 200 -1204 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GTCAYRTG MEME-5 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 42 E= 1.3e-008 0.214286 0.000000 0.785714 0.000000 0.095238 0.119048 0.000000 0.785714 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.571429 0.071429 0.357143 0.476190 0.000000 0.523810 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GTCAYRTG MEME-5 regular expression -------------------------------------------------------------------------------- [GA]TCA[CT][GA]TG -------------------------------------------------------------------------------- Time 18.85 secs. ******************************************************************************** ******************************************************************************** SUMMARY OF MOTIFS ******************************************************************************** -------------------------------------------------------------------------------- Combined block diagrams: non-overlapping sites with p-value < 0.0001 -------------------------------------------------------------------------------- SEQUENCE NAME COMBINED P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr10:119656186-11965626 5.62e-06 28_[+1(1.63e-05)]_10_[+5(3.11e-05)]_\ 11_[+4(2.76e-05)]_7 chr10:4376481-4376561 3.73e-01 80 chr21:44612406-44612486 1.52e-01 80 chr2:101356348-101356428 2.38e-02 80 chr20:54747785-54747865 1.17e-01 80 chr2:149838048-149838128 1.47e-01 80 chr12:115587742-11558782 6.98e-04 36_[+3(1.69e-05)]_5_[+2(2.59e-05)]_\ 23 chr3:85007866-85007946 1.83e-01 80 chr4:6179672-6179752 2.70e-02 45_[+3(3.30e-05)]_27 chr20:45501438-45501518 5.94e-02 80 chr20:1757974-1758054 1.68e-01 80 chr1:185663255-185663335 2.41e-02 41_[+2(1.25e-05)]_31 chr16:84277506-84277586 5.17e-03 9_[+4(8.44e-05)]_52_[+4(2.76e-05)]_\ 3 chr19:37742713-37742793 5.25e-04 80 chr1:30417187-30417267 1.05e-01 29_[+2(2.59e-05)]_43 chr16:86945047-86945127 6.27e-03 58_[+3(1.69e-05)]_6_[+3(1.69e-05)] chr11:123349168-12334924 6.18e-02 80 chr2:2061126-2061206 5.33e-01 80 chr16:5566305-5566385 3.74e-02 12_[+3(5.07e-05)]_8_[+3(1.69e-05)]_\ 26_[+3(1.69e-05)]_10 chr1:19318258-19318338 1.61e-04 18_[+1(8.07e-05)]_30_[+4(4.16e-05)]_\ 16 chr7:132242542-132242622 4.11e-03 24_[+2(7.77e-05)]_9_[+3(1.69e-05)]_\ 31 chr7:6749604-6749684 4.66e-03 [+1(4.90e-05)]_72 chr2:180446439-180446519 1.71e-04 69_[+3(8.30e-05)]_3 chr16:79444052-79444132 5.14e-02 80 chr1:237392797-237392877 3.15e-03 80 chr17:1016169-1016249 4.43e-01 80 chr19:36822613-36822693 7.37e-04 25_[+3(8.30e-05)]_14_[+3(8.30e-05)]_\ 25 chr12:113399100-11339918 2.43e-03 6_[+4(1.41e-05)]_66 chr13:48478577-48478657 3.08e-01 80 chr5:178587769-178587849 4.76e-06 24_[+3(1.69e-05)]_12_[+2(7.77e-05)]_\ 18_[+4(4.16e-05)]_2 chr12:105817868-10581794 1.53e-02 28_[+5(3.11e-05)]_44 chr19:8754986-8755066 7.24e-04 11_[+1(3.24e-05)]_29_[+4(4.16e-05)]_\ 24 chr21:33406912-33406992 4.82e-07 11_[+1(4.90e-05)]_10_[+5(3.11e-05)]_\ 11_[+4(2.76e-05)]_24 chr7:4699329-4699409 2.24e-03 31_[+2(1.25e-05)]_41 chr21:43594400-43594480 1.94e-04 53_[+1(1.63e-05)]_10_[+5(1.59e-05)]_\ 1 chr6:170475575-170475655 5.27e-02 23_[+3(8.30e-05)]_49 chr1:5409009-5409089 4.77e-02 80 chr16:86245591-86245671 5.25e-02 28_[+3(1.69e-05)]_7_[+3(1.69e-05)]_\ 7_[+3(1.69e-05)]_14 chr17:63382001-63382081 8.18e-02 80 chr16:50685918-50685998 7.33e-05 48_[+5(3.11e-05)]_24 chr19:57276640-57276720 7.50e-02 54_[+3(8.30e-05)]_18 chr19:50679382-50679462 4.85e-02 4_[+2(1.25e-05)]_68 chr16:86295143-86295223 5.09e-05 64_[+3(1.69e-05)]_8 chr16:86192454-86192534 6.38e-03 3_[+2(2.59e-05)]_10_[+2(2.59e-05)]_\ 10_[+2(2.59e-05)]_6_[+2(2.59e-05)]_19 chr6:166901734-166901814 4.94e-01 80 chr12:4872157-4872237 2.58e-01 80 chr15:79477771-79477851 7.56e-01 80 chr8:136685743-136685823 9.04e-03 58_[+5(3.11e-05)]_14 chr22:43717076-43717156 1.63e-01 39_[+2(2.59e-05)]_16_[+2(2.59e-05)]_\ 9 chr21:45525417-45525497 3.12e-01 80 chr20:60000900-60000980 2.26e-02 80 chr10:4375777-4375857 4.44e-01 80 chr22:23358782-23358862 1.14e-01 80 chr2:105593406-105593486 6.08e-03 14_[+2(1.25e-05)]_14_[+2(1.25e-05)]_\ 36 chr1:37331118-37331198 3.87e-01 80 chr10:12824677-12824757 2.90e-02 6_[+2(2.59e-05)]_66 chr17:32080598-32080678 1.55e-01 80 chr10:30368527-30368607 2.86e-02 23_[+4(8.44e-05)]_49 chr19:17552370-17552450 1.13e-02 12_[+1(3.24e-05)]_60 chr3:39527214-39527294 2.37e-02 26_[+1(1.63e-05)]_46 chr21:18715541-18715621 2.28e-01 80 chr21:47483346-47483426 2.56e-02 19_[+1(1.63e-05)]_53 chr19:37808732-37808812 9.49e-04 80 chr11:60425427-60425507 1.15e-01 80 chr19:58239033-58239113 1.42e-01 24_[+1(4.90e-05)]_48 chr10:14420733-14420813 2.42e-03 9_[+1(1.63e-05)]_12_[+5(4.74e-05)]_\ 43 chr3:11017639-11017719 2.10e-03 48_[+1(9.75e-05)]_10_[+5(4.74e-05)]_\ 6 chr10:75011880-75011960 4.10e-01 80 chr16:21716208-21716288 1.39e-03 26_[+1(1.63e-05)]_46 chr15:70202231-70202311 1.96e-03 13_[+1(1.63e-05)]_9_[+5(3.11e-05)]_\ 42 chr19:51465632-51465712 2.70e-02 80 chr10:4446038-4446118 3.25e-02 80 chr19:46456630-46456710 7.16e-04 43_[+3(3.30e-05)]_5_[+2(5.13e-05)]_\ 16 chr1:171283153-171283233 5.74e-02 80 chr7:67383325-67383405 6.50e-02 31_[+2(1.25e-05)]_25_[+2(1.25e-05)]_\ 8 chr10:49407755-49407835 4.44e-01 80 chr6:169295357-169295437 2.28e-01 80 chr19:52956744-52956824 9.24e-03 80 chr15:69818058-69818138 1.22e-03 17_[+1(3.24e-05)]_55 chrX:1033532-1033612 7.61e-02 80 chr2:601090-601170 1.30e-01 8_[+4(8.44e-05)]_31_[+4(8.44e-05)]_\ 25 chrX:27417139-27417219 5.69e-01 80 chr20:49609754-49609834 2.04e-02 41_[+4(1.41e-05)]_31 chr18:61157733-61157813 3.38e-02 62_[+3(3.30e-05)]_10 chr21:37522659-37522739 2.15e-01 80 chr20:43858254-43858334 4.82e-03 41_[+3(5.07e-05)]_22_[+3(8.30e-05)]_\ 1 chr19:10114163-10114243 9.09e-03 26_[+2(2.59e-05)]_13_[+2(2.59e-05)]_\ 25 chr11:102504368-10250444 4.28e-01 80 chr16:8561604-8561684 2.76e-03 22_[+5(4.74e-05)]_33_[+5(4.74e-05)]_\ 9 chr17:2952251-2952331 5.71e-02 29_[+1(4.90e-05)]_43 chr8:140495754-140495834 6.61e-03 66_[+3(1.69e-05)]_6 chr11:6846697-6846777 1.16e-01 80 chr14:76618068-76618148 8.82e-02 56_[+3(5.07e-05)]_16 chr15:80792030-80792110 2.36e-04 8_[+4(2.76e-05)]_28_[+1(8.07e-05)]_\ 28 chr2:42068077-42068157 5.24e-02 8_[+4(1.41e-05)]_64 chr11:45275371-45275451 5.49e-04 60_[+2(6.44e-05)]_12 chr3:13711956-13712036 1.77e-03 61_[+3(1.69e-05)]_11 chr16:19165366-19165446 1.55e-02 80 chr6:51928493-51928573 5.93e-03 29_[+3(3.30e-05)]_43 chr1:173399480-173399560 9.83e-01 80 chr2:68515545-68515625 8.57e-01 80 chr19:6953125-6953205 6.05e-03 46_[+3(3.30e-05)]_26 chr3:2895578-2895658 1.47e-01 80 chr12:132076987-13207706 1.22e-03 6_[+1(3.24e-05)]_29_[+4(5.49e-05)]_\ 29 chr21:32862957-32863037 1.06e-05 38_[+2(1.25e-05)]_14_[+2(7.77e-05)]_\ 12 chr15:38056962-38057042 7.88e-01 80 chr17:56307-56387 1.28e-02 33_[+1(3.24e-05)]_39 chr17:71848258-71848338 8.85e-03 80 chr8:17549751-17549831 7.03e-06 19_[+5(4.74e-05)]_11_[+4(4.16e-05)]_\ 34 chr5:140420832-140420912 4.70e-01 80 chr21:44030005-44030085 3.53e-03 25_[+1(4.90e-05)]_47 chr16:8438840-8438920 2.27e-05 40_[+5(9.28e-05)]_11_[+4(2.76e-05)]_\ 13 chr20:39541999-39542079 5.24e-02 80 chr19:21182656-21182736 1.82e-03 [+4(8.44e-05)]_20_[+4(8.44e-05)]_13_\ [+2(3.82e-05)]_23 chr19:41173082-41173162 4.48e-01 80 chr19:51402978-51403058 7.12e-03 50_[+3(8.30e-05)]_[+1(6.54e-05)]_14 chr1:189828752-189828832 7.09e-01 80 chr1:33704106-33704186 2.41e-06 10_[+1(3.24e-05)]_29_[+4(1.41e-05)]_\ 25 chr16:67541356-67541436 2.34e-01 80 chr12:132999960-13300004 1.66e-04 40_[+5(7.82e-05)]_11_[+4(1.41e-05)]_\ 13 chr16:3481922-3482002 7.24e-03 7_[+2(2.59e-05)]_5_[+2(2.59e-05)]_\ 14_[+3(8.30e-05)]_30 chr2:356516-356596 2.54e-01 42_[+3(8.30e-05)]_30 chr16:13228871-13228951 1.04e-03 35_[+5(3.11e-05)]_37 chr16:27879263-27879343 4.00e-01 80 chr1:244427627-244427707 7.24e-03 80 chr10:50543663-50543743 1.16e-01 53_[+3(1.69e-05)]_19 chr2:25640817-25640897 7.02e-06 15_[+4(4.16e-05)]_5_[+2(3.82e-05)]_\ 11_[+3(1.69e-05)]_25 chr12:115630264-11563034 2.56e-02 80 chr2:177646478-177646558 5.66e-02 23_[+2(1.25e-05)]_16_[+2(1.25e-05)]_\ 25 chr7:127903588-127903668 1.35e-03 67_[+5(9.28e-05)]_5 chr17:7909360-7909440 1.33e-02 80 chr12:127944432-12794451 6.45e-02 19_[+3(3.30e-05)]_53 chr10:50008451-50008531 2.31e-02 25_[+2(1.25e-05)]_47 chr8:142583645-142583725 2.61e-03 [+4(2.76e-05)]_26_[+1(1.63e-05)]_12_\ [+4(2.76e-05)]_18 chr17:72355088-72355168 1.15e-02 6_[+2(1.25e-05)]_66 chr1:29839997-29840077 2.50e-04 48_[+1(1.63e-05)]_10_[+5(4.74e-05)]_\ 6 chr1:203273920-203274000 9.51e-01 80 chr1:5782051-5782131 2.57e-02 7_[+1(3.24e-05)]_65 chr6:168091419-168091499 3.92e-02 26_[+3(8.30e-05)]_46 chr4:165877999-165878079 7.38e-03 46_[+2(6.44e-05)]_16_[+1(3.24e-05)]_\ 2 chr8:49419870-49419950 6.79e-02 9_[+4(2.76e-05)]_39_[+4(2.76e-05)]_\ 16 chr12:107987630-10798771 5.64e-02 80 chr12:131978149-13197822 8.02e-03 57_[+1(3.24e-05)]_15 chr6:26576832-26576912 9.97e-01 80 chr19:17131814-17131894 6.99e-04 32_[+4(2.76e-05)]_25_[+1(3.24e-05)]_\ 7 chr1:36614423-36614503 9.22e-01 80 chr1:155050229-155050309 5.92e-01 80 chr21:39748284-39748364 1.26e-03 33_[+2(1.25e-05)]_39 chr11:124994188-12499426 1.76e-02 80 chr15:90692331-90692411 6.94e-01 80 chr10:28967438-28967518 9.73e-01 80 chr5:21459515-21459595 8.24e-02 80 chr5:126560262-126560342 1.10e-03 47_[+1(3.24e-05)]_25 chr1:220906484-220906564 5.60e-02 44_[+3(3.30e-05)]_28 chr6:168476477-168476557 6.23e-02 80 chr6:2784184-2784264 3.53e-01 80 chr6:157340155-157340235 2.60e-02 80 chr18:73967148-73967228 3.69e-02 80 chr10:133622565-13362264 3.25e-03 21_[+5(3.11e-05)]_51 chr8:143799594-143799674 6.52e-03 26_[+2(2.59e-05)]_12_[+2(2.59e-05)]_\ 26 chrX:8723333-8723413 7.57e-03 35_[+3(1.69e-05)]_37 chr20:36857042-36857122 1.57e-05 28_[+1(3.24e-05)]_14_[+5(4.74e-05)]_\ 9_[+4(4.16e-05)]_5 chr3:4861339-4861419 9.38e-02 80 chr2:2257496-2257576 1.53e-01 12_[+2(1.25e-05)]_23_[+2(1.25e-05)]_\ 29 chr19:52901108-52901188 1.22e-01 80 chr4:6410184-6410264 4.55e-03 7_[+4(1.41e-05)]_65 chr1:211431503-211431583 5.45e-01 80 chr17:73088220-73088300 8.99e-01 80 chr1:52071669-52071749 2.01e-01 80 chr7:25894460-25894540 1.86e-01 80 chr17:39789043-39789123 7.00e-01 80 chr19:57742273-57742353 2.25e-01 80 chr11:15165601-15165681 2.08e-03 2_[+1(1.63e-05)]_10_[+5(4.74e-05)]_\ 52 chr9:99776164-99776244 6.64e-01 80 chr19:13446065-13446145 2.75e-02 80 chr19:9517707-9517787 2.31e-01 80 chr20:42846401-42846481 8.03e-01 80 chr16:6737782-6737862 1.07e-02 30_[+5(3.11e-05)]_42 chr7:149983393-149983473 8.40e-01 80 chr19:55959473-55959553 9.13e-01 80 chr10:132886956-13288703 4.00e-01 80 chr19:6564606-6564686 3.01e-02 46_[+1(1.63e-05)]_26 chr19:13755587-13755667 3.69e-05 5_[+1(1.63e-05)]_10_[+5(9.28e-05)]_\ 11_[+4(4.16e-05)]_16_[+1(1.63e-05)]_6 chr3:44754055-44754135 1.73e-01 80 chr20:61958493-61958573 5.84e-03 39_[+3(1.69e-05)]_14_[+3(1.69e-05)]_\ 11 chr16:85450390-85450470 9.82e-01 80 chr1:171798099-171798179 2.20e-03 55_[+2(3.82e-05)]_17 chr1:37889607-37889687 1.56e-01 80 chr19:21541698-21541778 2.98e-03 5_[+4(8.44e-05)]_21_[+4(8.44e-05)]_\ 26_[+3(8.30e-05)]_4 chr7:130032313-130032393 9.06e-01 80 chr19:51497560-51497640 5.10e-04 2_[+5(9.28e-05)]_14_[+1(1.63e-05)]_\ 34_[+1(8.07e-05)]_6 chr1:19007937-19008017 2.96e-01 80 chr2:70588002-70588082 9.15e-01 80 chr7:137687490-137687570 1.90e-01 80 chr16:85995918-85995998 8.85e-04 59_[+5(3.11e-05)]_13 chr13:92374643-92374723 2.25e-01 80 chr3:170241121-170241201 3.64e-02 80 chr2:240832675-240832755 9.24e-07 9_[+2(2.59e-05)]_18_[+1(1.63e-05)]_\ 29_[+4(1.41e-05)] chr6:58287732-58287812 8.00e-02 47_[+3(5.07e-05)]_25 chr3:10739824-10739904 6.15e-06 3_[+1(8.07e-05)]_29_[+4(4.16e-05)]_\ 32 chr19:21105980-21106060 5.20e-03 23_[+4(8.44e-05)]_26_[+3(8.30e-05)]_\ 15 chr19:7220021-7220101 4.79e-06 17_[+1(1.63e-05)]_10_[+5(4.74e-05)]_\ 11_[+4(1.41e-05)]_18 chr19:14032088-14032168 1.02e-02 80 chr14:89498574-89498654 2.42e-05 33_[+5(3.11e-05)]_8_[+5(7.82e-05)]_\ 4_[+2(7.77e-05)]_11 chr1:105249535-105249615 7.67e-02 52_[+1(1.63e-05)]_20 chr8:3442532-3442612 4.36e-02 80 chr4:18077624-18077704 2.36e-02 17_[+3(5.07e-05)]_25_[+3(5.07e-05)]_\ 22 chr16:88355088-88355168 7.79e-02 29_[+1(1.63e-05)]_43 chr3:33532430-33532510 1.88e-01 80 chr11:134314470-13431455 5.72e-01 80 chr7:6865935-6866015 3.09e-01 80 chr1:93970323-93970403 8.02e-01 80 chr8:64304073-64304153 4.09e-02 41_[+3(5.07e-05)]_31 chr8:102061435-102061515 7.22e-01 80 chr10:74032135-74032215 4.50e-01 80 chr6:151710294-151710374 1.98e-01 80 chr11:40315682-40315762 1.71e-02 57_[+1(1.63e-05)]_15 chr12:131365735-13136581 1.00e+00 80 chr1:17059456-17059536 8.29e-01 80 chr12:38710446-38710526 2.38e-01 80 chr19:40562081-40562161 6.54e-03 39_[+2(1.25e-05)]_33 chr22:46376796-46376876 9.99e-01 80 chr19:21579796-21579876 1.98e-02 53_[+4(8.44e-05)]_19 chr11:45615672-45615752 3.93e-04 7_[+1(3.24e-05)]_28_[+4(2.76e-05)]_\ 29 chr19:48453532-48453612 8.84e-01 80 chr3:10636745-10636825 1.64e-02 40_[+1(9.75e-05)]_32 chr12:131239160-13123924 2.67e-02 10_[+2(1.25e-05)]_10_[+2(5.13e-05)]_\ 7_[+2(5.13e-05)]_29 chr11:128027861-12802794 7.33e-01 80 chr19:12202911-12202991 6.83e-02 38_[+2(3.82e-05)]_34 chr7:87506567-87506647 8.16e-01 80 chr12:130991548-13099162 2.68e-04 1_[+1(3.24e-05)]_29_[+4(1.41e-05)]_\ 24_[+1(3.24e-05)]_2 chr1:224545544-224545624 7.69e-01 80 chr6:34038999-34039079 9.07e-01 80 chr6:31370541-31370621 1.30e-01 80 chr15:90000481-90000561 1.45e-04 58_[+1(4.90e-05)]_14 chr1:217804470-217804550 4.58e-01 80 chr7:158500511-158500591 9.83e-04 31_[+1(9.75e-05)]_24_[+1(1.63e-05)]_\ 9 chr14:106097241-10609732 3.29e-02 38_[+2(1.25e-05)]_34 chr7:100825924-100826004 2.92e-02 80 chr22:47666361-47666441 2.26e-03 54_[+4(1.41e-05)]_18 chr2:149403864-149403944 7.59e-01 80 chr19:20844415-20844495 1.93e-02 11_[+1(1.63e-05)]_21_[+1(1.63e-05)]_\ 32 chr7:126747877-126747957 1.89e-01 80 chr6:10403612-10403692 3.04e-01 80 chr11:129684710-12968479 1.26e-01 23_[+1(1.63e-05)]_49 chr19:2375538-2375618 9.52e-04 23_[+1(3.24e-05)]_20_[+4(2.76e-05)]_\ 21 chr2:220042428-220042508 4.09e-01 80 chr22:21192832-21192912 1.76e-01 80 chr9:100034206-100034286 9.80e-01 80 chr16:49958144-49958224 9.30e-06 2_[+4(2.76e-05)]_24_[+1(1.63e-05)]_\ 10_[+5(3.11e-05)]_20 -------------------------------------------------------------------------------- ******************************************************************************** ******************************************************************************** Stopped because requested number of motifs (5) found. ******************************************************************************** CPU: c22n07.farnam.hpc.yale.internal ********************************************************************************