******************************************************************************** MEME - Motif discovery tool ******************************************************************************** MEME version 5.3.3 (Release date: Sun Feb 7 15:39:52 2021 -0800) For further information on how to interpret these results please access https://meme-suite.org/meme. To get a copy of the MEME Suite software please access https://meme-suite.org. ******************************************************************************** ******************************************************************************** REFERENCE ******************************************************************************** If you use this program in your research, please cite: Timothy L. Bailey and Charles Elkan, "Fitting a mixture model by expectation maximization to discover motifs in biopolymers", Proceedings of the Second International Conference on Intelligent Systems for Molecular Biology, pp. 28-36, AAAI Press, Menlo Park, California, 1994. ******************************************************************************** ******************************************************************************** TRAINING SET ******************************************************************************** PRIMARY SEQUENCES= ../result/final_prediction/K562/fasta/RankLinear0.6_40/TRIM28.fasta CONTROL SEQUENCES= --none-- ALPHABET= ACGT Sequence name Weight Length Sequence name Weight Length ------------- ------ ------ ------------- ------ ------ chr10:76576957-76577037 1.0000 80 chr6:159326496-159326576 1.0000 80 chr1:197694357-197694437 1.0000 80 chr7:50286333-50286413 1.0000 80 chr7:18301867-18301947 1.0000 80 chr1:11817263-11817343 1.0000 80 chr1:236544990-236545070 1.0000 80 chr7:131021800-131021880 1.0000 80 chr1:234821938-234822018 1.0000 80 chr11:93708083-93708163 1.0000 80 chr7:106677158-106677238 1.0000 80 chr4:88164728-88164808 1.0000 80 chr9:132275690-132275770 1.0000 80 chr7:65730737-65730817 1.0000 80 chr2:113758157-113758237 1.0000 80 chr2:6971541-6971621 1.0000 80 chr3:43379894-43379974 1.0000 80 chr1:227530291-227530371 1.0000 80 chr2:6985648-6985728 1.0000 80 chr2:112962154-112962234 1.0000 80 chr1:243394321-243394401 1.0000 80 chr1:228386843-228386923 1.0000 80 chr1:154268247-154268327 1.0000 80 chr1:91344973-91345053 1.0000 80 chr7:2064976-2065056 1.0000 80 chr2:43096172-43096252 1.0000 80 chr2:3400055-3400135 1.0000 80 chr11:4015424-4015504 1.0000 80 chr12:111742525-11174260 1.0000 80 chr7:12741187-12741267 1.0000 80 chr3:14946701-14946781 1.0000 80 chr7:99129090-99129170 1.0000 80 chr7:127835053-127835133 1.0000 80 chr1:224359010-224359090 1.0000 80 chr5:154066221-154066301 1.0000 80 chr1:54399986-54400066 1.0000 80 chr5:134318122-134318202 1.0000 80 chr1:224531447-224531527 1.0000 80 chr3:150393495-150393575 1.0000 80 chr3:72274063-72274143 1.0000 80 chr7:149226354-149226434 1.0000 80 chr6:13942342-13942422 1.0000 80 chr7:99536058-99536138 1.0000 80 chr21:38721025-38721105 1.0000 80 chr7:92418052-92418132 1.0000 80 chr3:183371138-183371218 1.0000 80 chr10:1024883-1024963 1.0000 80 chr21:46242967-46243047 1.0000 80 chr2:86977540-86977620 1.0000 80 chr2:25117762-25117842 1.0000 80 chr5:173019232-173019312 1.0000 80 chr1:53603573-53603653 1.0000 80 chr20:33784292-33784372 1.0000 80 chr3:196710245-196710325 1.0000 80 chr4:2134335-2134415 1.0000 80 chr16:58306897-58306977 1.0000 80 chr7:35731729-35731809 1.0000 80 chr9:125702994-125703074 1.0000 80 chr10:75077155-75077235 1.0000 80 chr6:18824156-18824236 1.0000 80 chr19:6292209-6292289 1.0000 80 chr1:114389407-114389487 1.0000 80 chr6:43924446-43924526 1.0000 80 chr20:36871404-36871484 1.0000 80 chr2:158579308-158579388 1.0000 80 chr14:103829314-10382939 1.0000 80 chr15:67977564-67977644 1.0000 80 chr9:101127651-101127731 1.0000 80 chr20:61779031-61779111 1.0000 80 chr1:9589418-9589498 1.0000 80 chr21:46248751-46248831 1.0000 80 chr1:117437856-117437936 1.0000 80 chr7:64869083-64869163 1.0000 80 chr10:74397406-74397486 1.0000 80 chr21:46821123-46821203 1.0000 80 chr19:2933606-2933686 1.0000 80 chr2:38966835-38966915 1.0000 80 chr22:19304390-19304470 1.0000 80 chr8:127288161-127288241 1.0000 80 chr11:76487669-76487749 1.0000 80 chr6:158379253-158379333 1.0000 80 chr4:185057815-185057895 1.0000 80 chr8:23457948-23458028 1.0000 80 chr19:13211049-13211129 1.0000 80 chr7:99669127-99669207 1.0000 80 chr7:155441533-155441613 1.0000 80 chr19:19579397-19579477 1.0000 80 chr7:97726480-97726560 1.0000 80 chr1:203064350-203064430 1.0000 80 chr5:125980995-125981075 1.0000 80 chr18:77782822-77782902 1.0000 80 chr19:970793-970873 1.0000 80 chr9:101223204-101223284 1.0000 80 chr7:130940191-130940271 1.0000 80 chr20:726500-726580 1.0000 80 chr21:30568848-30568928 1.0000 80 chr4:95348091-95348171 1.0000 80 chr7:149163628-149163708 1.0000 80 chr3:138487096-138487176 1.0000 80 chr7:154976769-154976849 1.0000 80 chr7:149408070-149408150 1.0000 80 chr12:23676409-23676489 1.0000 80 chr7:86957784-86957864 1.0000 80 chr10:5432710-5432790 1.0000 80 chr9:138787202-138787282 1.0000 80 chr8:2595612-2595692 1.0000 80 chr5:148990519-148990599 1.0000 80 chr1:29706121-29706201 1.0000 80 chr2:97043186-97043266 1.0000 80 chr5:10740665-10740745 1.0000 80 chr7:156526536-156526616 1.0000 80 chr10:5207852-5207932 1.0000 80 chr1:95100717-95100797 1.0000 80 chr4:25052511-25052591 1.0000 80 chr22:23012707-23012787 1.0000 80 chr1:166483459-166483539 1.0000 80 chr5:77822962-77823042 1.0000 80 chr9:135572835-135572915 1.0000 80 chr20:32535651-32535731 1.0000 80 chr6:27282017-27282097 1.0000 80 chr16:88609773-88609853 1.0000 80 chr19:12638392-12638472 1.0000 80 chr2:178342896-178342976 1.0000 80 chr19:55439853-55439933 1.0000 80 chr1:55109547-55109627 1.0000 80 chr21:38774720-38774800 1.0000 80 chr1:207051967-207052047 1.0000 80 chr18:48488513-48488593 1.0000 80 chr9:132064369-132064449 1.0000 80 chr2:48575035-48575115 1.0000 80 chr8:145838908-145838988 1.0000 80 chr12:132678761-13267884 1.0000 80 chr6:74238827-74238907 1.0000 80 chr1:2578430-2578510 1.0000 80 chr6:106161567-106161647 1.0000 80 chr10:82256439-82256519 1.0000 80 chr17:48217483-48217563 1.0000 80 chr2:127300854-127300934 1.0000 80 chr6:35662357-35662437 1.0000 80 chr1:237079672-237079752 1.0000 80 chr17:81090563-81090643 1.0000 80 chr19:7083153-7083233 1.0000 80 chr19:9676726-9676806 1.0000 80 chr1:70005887-70005967 1.0000 80 chr6:163929132-163929212 1.0000 80 chr8:125959300-125959380 1.0000 80 chr19:58708513-58708593 1.0000 80 chr11:17393341-17393421 1.0000 80 chr1:226169539-226169619 1.0000 80 chr1:63109120-63109200 1.0000 80 chr2:28378642-28378722 1.0000 80 chr19:44980912-44980992 1.0000 80 chr11:77526064-77526144 1.0000 80 chr1:32860290-32860370 1.0000 80 chr6:119217817-119217897 1.0000 80 chr7:128523733-128523813 1.0000 80 chr7:138212543-138212623 1.0000 80 chr6:24431410-24431490 1.0000 80 chr9:136462858-136462938 1.0000 80 chr5:121462211-121462291 1.0000 80 chr11:82503018-82503098 1.0000 80 chr4:151695363-151695443 1.0000 80 chr11:87049241-87049321 1.0000 80 chr22:21094999-21095079 1.0000 80 chr11:70295273-70295353 1.0000 80 chr9:37197248-37197328 1.0000 80 chr1:92868686-92868766 1.0000 80 chr6:108563615-108563695 1.0000 80 chr1:234740766-234740846 1.0000 80 chr6:157346771-157346851 1.0000 80 chr19:13694030-13694110 1.0000 80 chr7:151406900-151406980 1.0000 80 chr5:10708817-10708897 1.0000 80 chr7:119566128-119566208 1.0000 80 chr6:154996845-154996925 1.0000 80 chr19:7078179-7078259 1.0000 80 chr16:50705723-50705803 1.0000 80 chr10:72408401-72408481 1.0000 80 chr8:21818147-21818227 1.0000 80 chr12:117566199-11756627 1.0000 80 chr7:10747320-10747400 1.0000 80 chr2:180652424-180652504 1.0000 80 chr7:24903950-24904030 1.0000 80 chr8:127616241-127616321 1.0000 80 chr6:28156060-28156140 1.0000 80 chr4:146433218-146433298 1.0000 80 chr1:48643108-48643188 1.0000 80 chr7:16384741-16384821 1.0000 80 chr10:71309934-71310014 1.0000 80 chr9:130188243-130188323 1.0000 80 chr12:51193898-51193978 1.0000 80 chr16:3367503-3367583 1.0000 80 chr10:58130654-58130734 1.0000 80 chr2:175057518-175057598 1.0000 80 chr9:126590944-126591024 1.0000 80 chr4:81174834-81174914 1.0000 80 chr8:42344136-42344216 1.0000 80 chr8:8293280-8293360 1.0000 80 chr20:36966215-36966295 1.0000 80 chr12:102090641-10209072 1.0000 80 chr5:111885567-111885647 1.0000 80 chr5:131987936-131988016 1.0000 80 chr5:140985337-140985417 1.0000 80 chr6:21102083-21102163 1.0000 80 chr3:39565752-39565832 1.0000 80 chr22:19636081-19636161 1.0000 80 chr4:154449977-154450057 1.0000 80 chr6:150881296-150881376 1.0000 80 chr10:45991401-45991481 1.0000 80 chr6:20575564-20575644 1.0000 80 chr10:103335818-10333589 1.0000 80 chr8:144751382-144751462 1.0000 80 chr10:6515504-6515584 1.0000 80 chr3:143002392-143002472 1.0000 80 chr9:125016696-125016776 1.0000 80 chr6:157811396-157811476 1.0000 80 chr10:94422756-94422836 1.0000 80 chr6:157927071-157927151 1.0000 80 chr2:54304740-54304820 1.0000 80 chr1:168421748-168421828 1.0000 80 chr7:138114456-138114536 1.0000 80 chr18:3461176-3461256 1.0000 80 chr4:160116710-160116790 1.0000 80 chr7:16779997-16780077 1.0000 80 chr1:192946629-192946709 1.0000 80 chr7:5123150-5123230 1.0000 80 chr12:90072118-90072198 1.0000 80 chr3:33740970-33741050 1.0000 80 chr4:25225524-25225604 1.0000 80 chr12:127661495-12766157 1.0000 80 chr9:72046808-72046888 1.0000 80 chr3:98302754-98302834 1.0000 80 chr9:130285823-130285903 1.0000 80 chr14:70107795-70107875 1.0000 80 chr1:57684554-57684634 1.0000 80 chr4:95471626-95471706 1.0000 80 chr5:178110968-178111048 1.0000 80 chr4:103277050-103277130 1.0000 80 chr1:244739731-244739811 1.0000 80 chr2:146172886-146172966 1.0000 80 chr10:5561150-5561230 1.0000 80 chrX:130086541-130086621 1.0000 80 chr10:127293930-12729401 1.0000 80 chr10:11183687-11183767 1.0000 80 chr3:105333298-105333378 1.0000 80 chr5:180301065-180301145 1.0000 80 chr1:200916329-200916409 1.0000 80 chr2:44537584-44537664 1.0000 80 chr16:8688291-8688371 1.0000 80 chr6:80314372-80314452 1.0000 80 ******************************************************************************** ******************************************************************************** COMMAND LINE SUMMARY ******************************************************************************** This information can also be useful in the event you wish to report a problem with the MEME software. command: meme -oc ../result/final_prediction/K562/inference_raw/MEME/RankLinear0.6_40_TRIM28/ -dna -nmotifs 5 -w 8 -maxsize 250000 -nostatus ../result/final_prediction/K562/fasta/RankLinear0.6_40/TRIM28.fasta model: mod= zoops nmotifs= 5 evt= inf objective function: em= E-value of product of p-values starts= E-value of product of p-values strands: + width: minw= 8 maxw= 8 nsites: minsites= 2 maxsites= 250 wnsites= 0.8 theta: spmap= uni spfuzz= 0.5 em: prior= dirichlet b= 0.01 maxiter= 50 distance= 1e-05 trim: wg= 11 ws= 1 endgaps= yes data: n= 20000 N= 250 sample: seed= 0 hsfrac= 0 searchsize= 20000 norand= no csites= 1000 Letter frequencies in dataset: A 0.272 C 0.219 G 0.222 T 0.287 Background letter frequencies (from file dataset with add-one prior applied): A 0.272 C 0.219 G 0.222 T 0.287 Background model order: 0 ******************************************************************************** ******************************************************************************** MOTIF WCWGCWGW MEME-1 width = 8 sites = 158 llr = 1068 E-value = 1.2e-075 ******************************************************************************** -------------------------------------------------------------------------------- Motif WCWGCWGW MEME-1 Description -------------------------------------------------------------------------------- Simplified A 3:7:24:6 pos.-specific C 1a:18::: probability G :::8::a: matrix T 5:31:6:4 bits 2.2 * * 2.0 * * 1.8 * * 1.5 * * Relative 1.3 * ** * Entropy 1.1 * ** * (9.8 bits) 0.9 **** * 0.7 ******* 0.4 ******** 0.2 ******** 0.0 -------- Multilevel TCAGCTGA consensus A T AA T sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif WCWGCWGW MEME-1 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr5:125980995-125981075 31 1.44e-05 tgccactgtt tcagctga aaagtcaact chr18:3461176-3461256 61 2.96e-05 tgatgagaca tcagctgt catttgtatc chr10:94422756-94422836 64 2.96e-05 tgataagaag tcagctgt taatcatgt chr8:42344136-42344216 45 2.96e-05 ctgatggaag tcagctgt ccatcttact chr4:146433218-146433298 53 2.96e-05 tgctgaaatg tcagctgt caacctgatt chr19:7078179-7078259 58 2.96e-05 tggtgacaaa tcagctgt taatcttgta chr1:63109120-63109200 32 2.96e-05 ctgtgataaa tcagctgt taggctaatt chr2:178342896-178342976 40 2.96e-05 tgctgataag tcagctgt taactttatg chr16:88609773-88609853 28 2.96e-05 tgaagagtag tcagctgt atttctttat chr12:23676409-23676489 49 2.96e-05 tgttgagaaa tcagctgt cgatcttatg chr7:97726480-97726560 53 2.96e-05 tgatgaaaag tcagctgt taatctcatt chr4:185057815-185057895 41 2.96e-05 tgttggaaag tcagctgt cagtcttatt chr20:61779031-61779111 25 2.96e-05 aaaacgaata tcagctgt ttccctgtgc chr16:58306897-58306977 49 2.96e-05 tgataagaaa tcagctgt taatcttgtt chr10:1024883-1024963 54 2.96e-05 tgttgagcag tcagctgt cacactcact chr21:38721025-38721105 41 2.96e-05 tgttgaaaaa tcagctgt cagtctaatt chr7:99536058-99536138 58 2.96e-05 tgaggagata tcagctgt taaacttatt chr3:72274063-72274143 39 2.96e-05 tggtggaaag tcagctgt taatcttatt chr1:224531447-224531527 36 2.96e-05 tgatgagaaa tcagctgt taatcttatt chr1:54399986-54400066 57 2.96e-05 tgatgtaaag tcagctgt cattagcact chr7:127835053-127835133 44 2.96e-05 ttatgggaag tcagctgt cacttgtagt chr7:12741187-12741267 25 2.96e-05 tgttgggagg tcagctgt tggtctaatt chr1:91344973-91345053 43 2.96e-05 tgaggataaa tcagctgt taatcttata chr1:228386843-228386923 36 2.96e-05 caatgagaaa tcagctgt taatctcagt chr3:43379894-43379974 39 2.96e-05 tgttgagaag tcagctgt ccatcttatc chr10:103335818-10333589 73 5.69e-05 aggccagaca tcagcaga chr10:45991401-45991481 22 5.69e-05 aaaaagatta acagctga cttatcctca chr22:19636081-19636161 37 5.69e-05 aataagattg acagctga tttctcacca chr6:108563615-108563695 51 5.69e-05 aataagatta acagctga cttctcacca chr11:87049241-87049321 29 5.69e-05 tccaagatta acagctga cttcctagca chr8:125959300-125959380 47 5.69e-05 aatatgatta acagctga tttttcatca chr2:127300854-127300934 7 5.69e-05 agaatt acagctga cttaccttca chr8:2595612-2595692 29 5.69e-05 caaaagataa acagctga tttctcacca chr10:5432710-5432790 47 5.69e-05 aataagatca acagctga cttttcaata chr19:19579397-19579477 19 5.69e-05 aataagatga acagctga cttctgactc chr2:38966835-38966915 34 5.69e-05 agtacaatta acagctga cttctcatct chr6:43924446-43924526 38 5.69e-05 aatataatta acagctga tttcagatca chr7:18301867-18301947 40 5.69e-05 aataaggctg acagctga tttctcttca chr7:50286333-50286413 24 5.69e-05 aattccactg acagctga ctttgcaaca chr17:48217483-48217563 49 7.21e-05 TGTTCCAAAG TCTGCTGA ATTAGCTGGG chr18:48488513-48488593 48 7.21e-05 tttcattgtt tctgctga gaagtcatct chr11:76487669-76487749 38 7.21e-05 tgatgagaaa tctgctga cagtcttatt chr14:103829314-10382939 39 7.21e-05 tgccaacgtt tctgctga gaaatctgct chr1:227530291-227530371 29 7.21e-05 ACAGACACAG TCTGCTGA ATCTCCTTCC chr1:57684554-57684634 34 1.14e-04 TTATCTAGCC ACAGCAGA ACATCCTGCT chr10:71309934-71310014 26 1.14e-04 gataacaatg acagcaga ctactcatca chr6:154996845-154996925 43 1.14e-04 ATAGAGTAAG ACAGCAGA GTAGGCCAAG chr9:136462858-136462938 42 1.14e-04 ggtaagaatg acagcaga ctccttgctg chr6:106161567-106161647 20 1.14e-04 aatgagaaat acagcaga ctgcttcaaa chr19:55439853-55439933 17 1.14e-04 GTTTTTAGTG ACAGCAGA CATCTCGATA chr7:149408070-149408150 19 1.14e-04 aattagactg acagcaga cttttcaata chr20:726500-726580 27 1.14e-04 aataagaccg acagcaga tttctcatgt chr9:101223204-101223284 22 1.14e-04 aataagtcag acagcaga ctcaatagaa chr1:243394321-243394401 14 1.14e-04 agtaagataa acagcaga tttcttctca chr2:6971541-6971621 29 1.14e-04 ccagaagggg acagcaga tttcccatca chr7:65730737-65730817 42 1.14e-04 agtaagatga acagcaga cttctcacca chr1:197694357-197694437 33 1.14e-04 tattacatcg acagcaga cttctcaata chr6:159326496-159326576 35 1.14e-04 agtaagatta acagcaga tttctcaaca chr14:70107795-70107875 37 1.30e-04 tgacactgaa tctgctgt aattctttgc chr6:20575564-20575644 46 1.30e-04 GCGGGGACCA TCTGCTGT GGTTCCCAGT chr3:39565752-39565832 37 1.30e-04 cactgagaga tctgctgt cagtctgctt chr1:2578430-2578510 28 1.30e-04 ctgggacaaa tctgctgt cattcgtgtt chr8:145838908-145838988 45 1.30e-04 tcatgagaaa tctgctgt catctgtgtc chr2:48575035-48575115 23 1.30e-04 tggtgagaag tctgctgt cattattcct chr1:207051967-207052047 14 1.30e-04 aaactctttc tctgctgt aatatcactg chr21:46821123-46821203 20 1.30e-04 tgcagatagt tctgctgt gcttcttatc chr1:114389407-114389487 30 1.30e-04 taatgcaaaa tctgctgt cattctaatt chr2:25117762-25117842 60 1.30e-04 tgaccacaca tctgctgt cattcttatc chr3:14946701-14946781 41 1.30e-04 tggtggaaag tctgctgt gatactcatg chr1:236544990-236545070 48 1.30e-04 tgatgaaaaa tctgctgt catccttgtt chr1:244739731-244739811 15 1.59e-04 aattttactt tctgcaga aagggtgctc chr7:138114456-138114536 39 1.59e-04 caaatttact tctgcaga agggtgctgc chr8:144751382-144751462 41 1.59e-04 caaatttact tctgcaga agagtgccgc chr9:72046808-72046888 25 1.72e-04 GTGGTAACTG ACAGCAGT GTTGACTGAC chr5:148990519-148990599 25 2.14e-04 ccctcaaata tctgcagt cacctgcagg chr8:23457948-23458028 40 2.14e-04 ggatgagaaa tctgcagt catctgaatt chr9:132275690-132275770 52 2.14e-04 ctatgagaag tctgcagt cttttgcagc chr1:55109547-55109627 34 2.45e-04 ctccatagtt tcagatga gaaatatgct chr10:75077155-75077235 15 2.45e-04 ttccattgtt tcagatga aaaatcagtg chr4:2134335-2134415 34 2.45e-04 aatgtgagtg actgcaga tttcctgtca chr5:178110968-178111048 51 2.57e-04 caaccacgag ccagctgt ggcgattaag chr6:21102083-21102163 37 2.57e-04 atcctacctc ccagctgt taatcagatc chr4:25225524-25225604 54 2.67e-04 gcactcagaa ccagcaga ttaacatccg chr4:81174834-81174914 35 3.01e-04 TCTTCTAGGG TCAGATGT GCTGCTGGAG chr9:126590944-126591024 26 3.60e-04 cataagactt acagatga ctttccagca chr7:156526536-156526616 49 3.60e-04 gataagtatg acagatga cttgttggaa chr7:99669127-99669207 11 3.60e-04 GGGTTGAGCT CCTGCTGA AGGCCTTCCC chr8:127288161-127288241 43 3.60e-04 tttatggaag tcagaaga taatgggaca chr7:149226354-149226434 24 3.60e-04 catgactact cctgctga ctagctctta chr6:35662357-35662437 72 4.01e-04 ttctgagtca tctgatga c chr9:132064369-132064449 38 4.01e-04 ctccataatt tctgatga aaagtcagtg chr7:155441533-155441613 15 4.01e-04 ttccatcgtt tctgatga gaaattgact chr6:158379253-158379333 23 4.01e-04 ttgcatagtt tctgatga caaatctgcc chr2:3400055-3400135 20 4.01e-04 ttgcatagtt tctgatga gaagtctgta chr7:106677158-106677238 49 4.01e-04 tgttgaggag tctgatga tgttctgatt chr1:11817263-11817343 56 4.01e-04 acaattactg gcagctga tgtctcaaca chr12:102090641-10209072 39 4.76e-04 CGTGTTTATG ACAGATGT CCCCTGTCCA chr20:36966215-36966295 17 4.76e-04 TCCTGTGTAG TCACCTgt ccactaggac chr7:16384741-16384821 47 4.76e-04 ttacttctca tcagaagt catggaggtc chr12:117566199-11756627 39 4.76e-04 cacgtcattg tcacctgt cacgtcattg chr5:121462211-121462291 21 4.76e-04 TGCCCACTCA ACAGATGT GAGCAGTTTA chr5:77822962-77823042 73 4.76e-04 CTCTCCTGCC TCAGCTGG chr1:9589418-9589498 22 4.76e-04 GCTGGTGACA TCAGCTGG AGCCTACGCC chr1:224359010-224359090 42 4.76e-04 tcatgaggag tcacctgt tcatcatatc chr3:33740970-33741050 20 5.30e-04 atacacaagt acagaaga tttccggcca chr5:111885567-111885647 41 5.30e-04 ACTCAAGTAG CCTGCAGA CATGATTGGA chr1:226169539-226169619 1 5.30e-04 . acacctga aagctgccaa chr6:27282017-27282097 3 5.30e-04 tt acagaaga accctaaaca chr21:46242967-46243047 18 5.30e-04 taaaggactt acacctga ctttgtgaca chr11:93708083-93708163 42 5.62e-04 tggtgagaag tctgatgt tagtctgatt chr12:132678761-13267884 64 6.42e-04 acaccgtgtg gcagcaga tgcaaaggc chr2:97043186-97043266 42 6.42e-04 ttccatagtt tctgaaga aaggtaggca chr9:138787202-138787282 32 6.42e-04 caaagacttc tcatctga agctatggag chr1:203064350-203064430 2 6.42e-04 a actgatga tttcccatca chr2:158579308-158579388 20 6.42e-04 aataagaatg gcagcaga tttctcacag chr1:48643108-48643188 30 7.21e-04 agggcagcag cctgcagt ttatgtaact chr19:13694030-13694110 48 7.21e-04 CTGGTTCTTT ACAGAAGT CTGCAAATCC chr19:12638392-12638472 33 7.21e-04 ATAGGGTTTC TCACCAGT GTGAGTTCTT chr7:86957784-86957864 48 7.21e-04 gaggagctag tcagcagg agtagccatg chr9:125016696-125016776 68 7.59e-04 ACTTTTATCT GCTGCTGA AGTGC chr10:74397406-74397486 62 7.59e-04 acagctcttt gctgctga ggcaaaactt chr4:25052511-25052591 15 8.56e-04 tactaaaCTC TCTCCTGT TAGGGTCAGA chr16:3367503-3367583 25 9.48e-04 AAGAATTCAC ACTGAAGA GAAACCCTAT chr12:51193898-51193978 46 9.48e-04 tacagagtgc tcatcaga aactatggag chr9:37197248-37197328 48 9.48e-04 AGCTCTTATC TCTCCAGA CCTGACATTG chr22:21094999-21095079 51 9.48e-04 tgttgacttc tctccaga aacaatgcaa chr1:32860290-32860370 37 9.48e-04 TGGACGATGA TCAGCCGA CAAGCTGGAC chr7:130940191-130940271 23 9.48e-04 aataagatta acatctga ctttctccaa chr20:33784292-33784372 43 9.48e-04 tgtagatttt tcatcaga gaccatggaa chr7:92418052-92418132 38 9.48e-04 caactacttc tcatcaga aactatggag chr3:150393495-150393575 17 9.48e-04 tttttaccac actgaaga cattccattg chr2:112962154-112962234 34 9.48e-04 aggtcacttc tcatcaga aactatggaa chr5:173019232-173019312 37 9.98e-04 gcactgttga acaccagt cctgcacagc chr2:146172886-146172966 39 1.05e-03 tttcatgact ccagaaga gcagtctgtg chr8:8293280-8293360 20 1.05e-03 tgttccactg tcttctga cttccattgt chr1:237079672-237079752 70 1.05e-03 aaaatgtaaa ccagaaga cag chr7:149163628-149163708 30 1.05e-03 tagtccattg tcttctga cttccatgtt chr4:95348091-95348171 72 1.05e-03 actatgtaag ccagaaga c chr1:117437856-117437936 56 1.05e-03 acactgtaag ccagaaga caatggaaat chr21:46248751-46248831 32 1.05e-03 actatgcaag ccagaaga caatgaagtg chr15:67977564-67977644 53 1.05e-03 gctatgcaag ccagaaga taatggaaag chr7:16779997-16780077 35 1.17e-03 AGCTGCTCAG ACTGCTGG GTCACTGCAT chr6:157346771-157346851 68 1.17e-03 gtttatccac tcatcagt tgaag chr19:9676726-9676806 53 1.17e-03 ATACGGTTTC TCTCCAGT GTGAGTTCTT chr22:19304390-19304470 71 1.17e-03 cctattggtc tctccagt ct chr7:131021800-131021880 36 1.17e-03 tgttgcaaaa tcagccgt cagacttact chr5:134318122-134318202 61 1.25e-03 aataagatta acagccga tttatcctca chr9:125702994-125703074 30 1.31e-03 CCCAGTCCCG GCTGCAGT CACGTAGTTG chr2:28378642-28378722 27 1.39e-03 cccataccaa ccaccaga tggggttatc chr1:154268247-154268327 47 1.39e-03 ggcagacttc tcttcaga aacaatggag chr5:10708817-10708897 31 1.49e-03 GGACTCCTAC ACTGCAGG CCCATATAGG chr3:138487096-138487176 67 1.49e-03 agcctgttgt cctgatgt ctgctg chr11:4015424-4015504 48 1.49e-03 cttactgggt tcacatgt gtgtgatgag chr11:77526064-77526144 31 1.74e-03 AGGTGGTGTG ACTTCAGA CATGAGGATC chr10:6515504-6515584 32 1.87e-03 ATCTGTCACT ACAGATGG GGGCAGCATG chr10:58130654-58130734 50 1.87e-03 cactaaagat cctcctgt attcaccccg chr1:234821938-234822018 9 1.87e-03 acagagga acacatgt aagggtgata chr1:95100717-95100797 2 2.05e-03 A GCAGCTGG TTATCATGAA -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif WCWGCWGW MEME-1 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr5:125980995-125981075 1.4e-05 30_[+1]_42 chr18:3461176-3461256 3e-05 60_[+1]_12 chr10:94422756-94422836 3e-05 63_[+1]_9 chr8:42344136-42344216 3e-05 44_[+1]_28 chr4:146433218-146433298 3e-05 52_[+1]_20 chr19:7078179-7078259 3e-05 57_[+1]_15 chr1:63109120-63109200 3e-05 31_[+1]_41 chr2:178342896-178342976 3e-05 39_[+1]_33 chr16:88609773-88609853 3e-05 27_[+1]_45 chr12:23676409-23676489 3e-05 48_[+1]_24 chr7:97726480-97726560 3e-05 52_[+1]_20 chr4:185057815-185057895 3e-05 40_[+1]_32 chr20:61779031-61779111 3e-05 24_[+1]_48 chr16:58306897-58306977 3e-05 48_[+1]_24 chr10:1024883-1024963 3e-05 53_[+1]_19 chr21:38721025-38721105 3e-05 40_[+1]_32 chr7:99536058-99536138 3e-05 57_[+1]_15 chr3:72274063-72274143 3e-05 38_[+1]_34 chr1:224531447-224531527 3e-05 35_[+1]_37 chr1:54399986-54400066 3e-05 56_[+1]_16 chr7:127835053-127835133 3e-05 43_[+1]_29 chr7:12741187-12741267 3e-05 24_[+1]_48 chr1:91344973-91345053 3e-05 42_[+1]_30 chr1:228386843-228386923 3e-05 35_[+1]_37 chr3:43379894-43379974 3e-05 38_[+1]_34 chr10:103335818-10333589 5.7e-05 72_[+1] chr10:45991401-45991481 5.7e-05 21_[+1]_51 chr22:19636081-19636161 5.7e-05 36_[+1]_36 chr6:108563615-108563695 5.7e-05 50_[+1]_22 chr11:87049241-87049321 5.7e-05 28_[+1]_44 chr8:125959300-125959380 5.7e-05 46_[+1]_26 chr2:127300854-127300934 5.7e-05 6_[+1]_66 chr8:2595612-2595692 5.7e-05 28_[+1]_44 chr10:5432710-5432790 5.7e-05 46_[+1]_26 chr19:19579397-19579477 5.7e-05 18_[+1]_54 chr2:38966835-38966915 5.7e-05 33_[+1]_39 chr6:43924446-43924526 5.7e-05 37_[+1]_35 chr7:18301867-18301947 5.7e-05 39_[+1]_33 chr7:50286333-50286413 5.7e-05 23_[+1]_49 chr17:48217483-48217563 7.2e-05 48_[+1]_24 chr18:48488513-48488593 7.2e-05 47_[+1]_25 chr11:76487669-76487749 7.2e-05 37_[+1]_35 chr14:103829314-10382939 7.2e-05 38_[+1]_34 chr1:227530291-227530371 7.2e-05 28_[+1]_44 chr1:57684554-57684634 0.00011 33_[+1]_39 chr10:71309934-71310014 0.00011 25_[+1]_47 chr6:154996845-154996925 0.00011 42_[+1]_30 chr9:136462858-136462938 0.00011 41_[+1]_31 chr6:106161567-106161647 0.00011 19_[+1]_53 chr19:55439853-55439933 0.00011 16_[+1]_56 chr7:149408070-149408150 0.00011 18_[+1]_54 chr20:726500-726580 0.00011 26_[+1]_46 chr9:101223204-101223284 0.00011 21_[+1]_51 chr1:243394321-243394401 0.00011 13_[+1]_59 chr2:6971541-6971621 0.00011 28_[+1]_44 chr7:65730737-65730817 0.00011 41_[+1]_31 chr1:197694357-197694437 0.00011 32_[+1]_40 chr6:159326496-159326576 0.00011 34_[+1]_38 chr14:70107795-70107875 0.00013 36_[+1]_36 chr6:20575564-20575644 0.00013 45_[+1]_27 chr3:39565752-39565832 0.00013 36_[+1]_36 chr1:2578430-2578510 0.00013 27_[+1]_45 chr8:145838908-145838988 0.00013 44_[+1]_28 chr2:48575035-48575115 0.00013 22_[+1]_50 chr1:207051967-207052047 0.00013 13_[+1]_59 chr21:46821123-46821203 0.00013 19_[+1]_53 chr1:114389407-114389487 0.00013 29_[+1]_43 chr2:25117762-25117842 0.00013 59_[+1]_13 chr3:14946701-14946781 0.00013 40_[+1]_32 chr1:236544990-236545070 0.00013 47_[+1]_25 chr1:244739731-244739811 0.00016 14_[+1]_58 chr7:138114456-138114536 0.00016 38_[+1]_34 chr8:144751382-144751462 0.00016 40_[+1]_32 chr9:72046808-72046888 0.00017 24_[+1]_48 chr5:148990519-148990599 0.00021 24_[+1]_48 chr8:23457948-23458028 0.00021 39_[+1]_33 chr9:132275690-132275770 0.00021 51_[+1]_21 chr1:55109547-55109627 0.00025 33_[+1]_39 chr10:75077155-75077235 0.00025 14_[+1]_58 chr4:2134335-2134415 0.00025 33_[+1]_39 chr5:178110968-178111048 0.00026 50_[+1]_22 chr6:21102083-21102163 0.00026 36_[+1]_36 chr4:25225524-25225604 0.00027 53_[+1]_19 chr4:81174834-81174914 0.0003 34_[+1]_38 chr9:126590944-126591024 0.00036 25_[+1]_47 chr7:156526536-156526616 0.00036 48_[+1]_24 chr7:99669127-99669207 0.00036 10_[+1]_62 chr8:127288161-127288241 0.00036 42_[+1]_30 chr7:149226354-149226434 0.00036 23_[+1]_49 chr6:35662357-35662437 0.0004 71_[+1]_1 chr9:132064369-132064449 0.0004 37_[+1]_35 chr7:155441533-155441613 0.0004 14_[+1]_58 chr6:158379253-158379333 0.0004 22_[+1]_50 chr2:3400055-3400135 0.0004 19_[+1]_53 chr7:106677158-106677238 0.0004 48_[+1]_24 chr1:11817263-11817343 0.0004 55_[+1]_17 chr12:102090641-10209072 0.00048 38_[+1]_34 chr20:36966215-36966295 0.00048 16_[+1]_56 chr7:16384741-16384821 0.00048 46_[+1]_26 chr12:117566199-11756627 0.00048 38_[+1]_34 chr5:121462211-121462291 0.00048 20_[+1]_52 chr5:77822962-77823042 0.00048 72_[+1] chr1:9589418-9589498 0.00048 21_[+1]_51 chr1:224359010-224359090 0.00048 41_[+1]_31 chr3:33740970-33741050 0.00053 19_[+1]_53 chr5:111885567-111885647 0.00053 40_[+1]_32 chr1:226169539-226169619 0.00053 [+1]_72 chr6:27282017-27282097 0.00053 2_[+1]_70 chr21:46242967-46243047 0.00053 17_[+1]_55 chr11:93708083-93708163 0.00056 41_[+1]_31 chr12:132678761-13267884 0.00064 63_[+1]_9 chr2:97043186-97043266 0.00064 41_[+1]_31 chr9:138787202-138787282 0.00064 31_[+1]_41 chr1:203064350-203064430 0.00064 1_[+1]_71 chr2:158579308-158579388 0.00064 19_[+1]_53 chr1:48643108-48643188 0.00072 29_[+1]_43 chr19:13694030-13694110 0.00072 47_[+1]_25 chr19:12638392-12638472 0.00072 32_[+1]_40 chr7:86957784-86957864 0.00072 47_[+1]_25 chr9:125016696-125016776 0.00076 67_[+1]_5 chr10:74397406-74397486 0.00076 61_[+1]_11 chr4:25052511-25052591 0.00086 14_[+1]_58 chr16:3367503-3367583 0.00095 24_[+1]_48 chr12:51193898-51193978 0.00095 45_[+1]_27 chr9:37197248-37197328 0.00095 47_[+1]_25 chr22:21094999-21095079 0.00095 50_[+1]_22 chr1:32860290-32860370 0.00095 36_[+1]_36 chr7:130940191-130940271 0.00095 22_[+1]_50 chr20:33784292-33784372 0.00095 42_[+1]_30 chr7:92418052-92418132 0.00095 37_[+1]_35 chr3:150393495-150393575 0.00095 16_[+1]_56 chr2:112962154-112962234 0.00095 33_[+1]_39 chr5:173019232-173019312 0.001 36_[+1]_36 chr2:146172886-146172966 0.0011 38_[+1]_34 chr8:8293280-8293360 0.0011 19_[+1]_53 chr1:237079672-237079752 0.0011 69_[+1]_3 chr7:149163628-149163708 0.0011 29_[+1]_43 chr4:95348091-95348171 0.0011 71_[+1]_1 chr1:117437856-117437936 0.0011 55_[+1]_17 chr21:46248751-46248831 0.0011 31_[+1]_41 chr15:67977564-67977644 0.0011 52_[+1]_20 chr7:16779997-16780077 0.0012 34_[+1]_38 chr6:157346771-157346851 0.0012 67_[+1]_5 chr19:9676726-9676806 0.0012 52_[+1]_20 chr22:19304390-19304470 0.0012 70_[+1]_2 chr7:131021800-131021880 0.0012 35_[+1]_37 chr5:134318122-134318202 0.0012 60_[+1]_12 chr9:125702994-125703074 0.0013 29_[+1]_43 chr2:28378642-28378722 0.0014 26_[+1]_46 chr1:154268247-154268327 0.0014 46_[+1]_26 chr5:10708817-10708897 0.0015 30_[+1]_42 chr3:138487096-138487176 0.0015 66_[+1]_6 chr11:4015424-4015504 0.0015 47_[+1]_25 chr11:77526064-77526144 0.0017 30_[+1]_42 chr10:6515504-6515584 0.0019 31_[+1]_41 chr10:58130654-58130734 0.0019 49_[+1]_23 chr1:234821938-234822018 0.0019 8_[+1]_64 chr1:95100717-95100797 0.0021 1_[+1]_71 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif WCWGCWGW MEME-1 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF WCWGCWGW width=8 seqs=158 chr5:125980995-125981075 ( 31) TCAGCTGA 1 chr18:3461176-3461256 ( 61) TCAGCTGT 1 chr10:94422756-94422836 ( 64) TCAGCTGT 1 chr8:42344136-42344216 ( 45) TCAGCTGT 1 chr4:146433218-146433298 ( 53) TCAGCTGT 1 chr19:7078179-7078259 ( 58) TCAGCTGT 1 chr1:63109120-63109200 ( 32) TCAGCTGT 1 chr2:178342896-178342976 ( 40) TCAGCTGT 1 chr16:88609773-88609853 ( 28) TCAGCTGT 1 chr12:23676409-23676489 ( 49) TCAGCTGT 1 chr7:97726480-97726560 ( 53) TCAGCTGT 1 chr4:185057815-185057895 ( 41) TCAGCTGT 1 chr20:61779031-61779111 ( 25) TCAGCTGT 1 chr16:58306897-58306977 ( 49) TCAGCTGT 1 chr10:1024883-1024963 ( 54) TCAGCTGT 1 chr21:38721025-38721105 ( 41) TCAGCTGT 1 chr7:99536058-99536138 ( 58) TCAGCTGT 1 chr3:72274063-72274143 ( 39) TCAGCTGT 1 chr1:224531447-224531527 ( 36) TCAGCTGT 1 chr1:54399986-54400066 ( 57) TCAGCTGT 1 chr7:127835053-127835133 ( 44) TCAGCTGT 1 chr7:12741187-12741267 ( 25) TCAGCTGT 1 chr1:91344973-91345053 ( 43) TCAGCTGT 1 chr1:228386843-228386923 ( 36) TCAGCTGT 1 chr3:43379894-43379974 ( 39) TCAGCTGT 1 chr10:103335818-10333589 ( 73) TCAGCAGA 1 chr10:45991401-45991481 ( 22) ACAGCTGA 1 chr22:19636081-19636161 ( 37) ACAGCTGA 1 chr6:108563615-108563695 ( 51) ACAGCTGA 1 chr11:87049241-87049321 ( 29) ACAGCTGA 1 chr8:125959300-125959380 ( 47) ACAGCTGA 1 chr2:127300854-127300934 ( 7) ACAGCTGA 1 chr8:2595612-2595692 ( 29) ACAGCTGA 1 chr10:5432710-5432790 ( 47) ACAGCTGA 1 chr19:19579397-19579477 ( 19) ACAGCTGA 1 chr2:38966835-38966915 ( 34) ACAGCTGA 1 chr6:43924446-43924526 ( 38) ACAGCTGA 1 chr7:18301867-18301947 ( 40) ACAGCTGA 1 chr7:50286333-50286413 ( 24) ACAGCTGA 1 chr17:48217483-48217563 ( 49) TCTGCTGA 1 chr18:48488513-48488593 ( 48) TCTGCTGA 1 chr11:76487669-76487749 ( 38) TCTGCTGA 1 chr14:103829314-10382939 ( 39) TCTGCTGA 1 chr1:227530291-227530371 ( 29) TCTGCTGA 1 chr1:57684554-57684634 ( 34) ACAGCAGA 1 chr10:71309934-71310014 ( 26) ACAGCAGA 1 chr6:154996845-154996925 ( 43) ACAGCAGA 1 chr9:136462858-136462938 ( 42) ACAGCAGA 1 chr6:106161567-106161647 ( 20) ACAGCAGA 1 chr19:55439853-55439933 ( 17) ACAGCAGA 1 chr7:149408070-149408150 ( 19) ACAGCAGA 1 chr20:726500-726580 ( 27) ACAGCAGA 1 chr9:101223204-101223284 ( 22) ACAGCAGA 1 chr1:243394321-243394401 ( 14) ACAGCAGA 1 chr2:6971541-6971621 ( 29) ACAGCAGA 1 chr7:65730737-65730817 ( 42) ACAGCAGA 1 chr1:197694357-197694437 ( 33) ACAGCAGA 1 chr6:159326496-159326576 ( 35) ACAGCAGA 1 chr14:70107795-70107875 ( 37) TCTGCTGT 1 chr6:20575564-20575644 ( 46) TCTGCTGT 1 chr3:39565752-39565832 ( 37) TCTGCTGT 1 chr1:2578430-2578510 ( 28) TCTGCTGT 1 chr8:145838908-145838988 ( 45) TCTGCTGT 1 chr2:48575035-48575115 ( 23) TCTGCTGT 1 chr1:207051967-207052047 ( 14) TCTGCTGT 1 chr21:46821123-46821203 ( 20) TCTGCTGT 1 chr1:114389407-114389487 ( 30) TCTGCTGT 1 chr2:25117762-25117842 ( 60) TCTGCTGT 1 chr3:14946701-14946781 ( 41) TCTGCTGT 1 chr1:236544990-236545070 ( 48) TCTGCTGT 1 chr1:244739731-244739811 ( 15) TCTGCAGA 1 chr7:138114456-138114536 ( 39) TCTGCAGA 1 chr8:144751382-144751462 ( 41) TCTGCAGA 1 chr9:72046808-72046888 ( 25) ACAGCAGT 1 chr5:148990519-148990599 ( 25) TCTGCAGT 1 chr8:23457948-23458028 ( 40) TCTGCAGT 1 chr9:132275690-132275770 ( 52) TCTGCAGT 1 chr1:55109547-55109627 ( 34) TCAGATGA 1 chr10:75077155-75077235 ( 15) TCAGATGA 1 chr4:2134335-2134415 ( 34) ACTGCAGA 1 chr5:178110968-178111048 ( 51) CCAGCTGT 1 chr6:21102083-21102163 ( 37) CCAGCTGT 1 chr4:25225524-25225604 ( 54) CCAGCAGA 1 chr4:81174834-81174914 ( 35) TCAGATGT 1 chr9:126590944-126591024 ( 26) ACAGATGA 1 chr7:156526536-156526616 ( 49) ACAGATGA 1 chr7:99669127-99669207 ( 11) CCTGCTGA 1 chr8:127288161-127288241 ( 43) TCAGAAGA 1 chr7:149226354-149226434 ( 24) CCTGCTGA 1 chr6:35662357-35662437 ( 72) TCTGATGA 1 chr9:132064369-132064449 ( 38) TCTGATGA 1 chr7:155441533-155441613 ( 15) TCTGATGA 1 chr6:158379253-158379333 ( 23) TCTGATGA 1 chr2:3400055-3400135 ( 20) TCTGATGA 1 chr7:106677158-106677238 ( 49) TCTGATGA 1 chr1:11817263-11817343 ( 56) GCAGCTGA 1 chr12:102090641-10209072 ( 39) ACAGATGT 1 chr20:36966215-36966295 ( 17) TCACCTGT 1 chr7:16384741-16384821 ( 47) TCAGAAGT 1 chr12:117566199-11756627 ( 39) TCACCTGT 1 chr5:121462211-121462291 ( 21) ACAGATGT 1 chr5:77822962-77823042 ( 73) TCAGCTGG 1 chr1:9589418-9589498 ( 22) TCAGCTGG 1 chr1:224359010-224359090 ( 42) TCACCTGT 1 chr3:33740970-33741050 ( 20) ACAGAAGA 1 chr5:111885567-111885647 ( 41) CCTGCAGA 1 chr1:226169539-226169619 ( 1) ACACCTGA 1 chr6:27282017-27282097 ( 3) ACAGAAGA 1 chr21:46242967-46243047 ( 18) ACACCTGA 1 chr11:93708083-93708163 ( 42) TCTGATGT 1 chr12:132678761-13267884 ( 64) GCAGCAGA 1 chr2:97043186-97043266 ( 42) TCTGAAGA 1 chr9:138787202-138787282 ( 32) TCATCTGA 1 chr1:203064350-203064430 ( 2) ACTGATGA 1 chr2:158579308-158579388 ( 20) GCAGCAGA 1 chr1:48643108-48643188 ( 30) CCTGCAGT 1 chr19:13694030-13694110 ( 48) ACAGAAGT 1 chr19:12638392-12638472 ( 33) TCACCAGT 1 chr7:86957784-86957864 ( 48) TCAGCAGG 1 chr9:125016696-125016776 ( 68) GCTGCTGA 1 chr10:74397406-74397486 ( 62) GCTGCTGA 1 chr4:25052511-25052591 ( 15) TCTCCTGT 1 chr16:3367503-3367583 ( 25) ACTGAAGA 1 chr12:51193898-51193978 ( 46) TCATCAGA 1 chr9:37197248-37197328 ( 48) TCTCCAGA 1 chr22:21094999-21095079 ( 51) TCTCCAGA 1 chr1:32860290-32860370 ( 37) TCAGCCGA 1 chr7:130940191-130940271 ( 23) ACATCTGA 1 chr20:33784292-33784372 ( 43) TCATCAGA 1 chr7:92418052-92418132 ( 38) TCATCAGA 1 chr3:150393495-150393575 ( 17) ACTGAAGA 1 chr2:112962154-112962234 ( 34) TCATCAGA 1 chr5:173019232-173019312 ( 37) ACACCAGT 1 chr2:146172886-146172966 ( 39) CCAGAAGA 1 chr8:8293280-8293360 ( 20) TCTTCTGA 1 chr1:237079672-237079752 ( 70) CCAGAAGA 1 chr7:149163628-149163708 ( 30) TCTTCTGA 1 chr4:95348091-95348171 ( 72) CCAGAAGA 1 chr1:117437856-117437936 ( 56) CCAGAAGA 1 chr21:46248751-46248831 ( 32) CCAGAAGA 1 chr15:67977564-67977644 ( 53) CCAGAAGA 1 chr7:16779997-16780077 ( 35) ACTGCTGG 1 chr6:157346771-157346851 ( 68) TCATCAGT 1 chr19:9676726-9676806 ( 53) TCTCCAGT 1 chr22:19304390-19304470 ( 71) TCTCCAGT 1 chr7:131021800-131021880 ( 36) TCAGCCGT 1 chr5:134318122-134318202 ( 61) ACAGCCGA 1 chr9:125702994-125703074 ( 30) GCTGCAGT 1 chr2:28378642-28378722 ( 27) CCACCAGA 1 chr1:154268247-154268327 ( 47) TCTTCAGA 1 chr5:10708817-10708897 ( 31) ACTGCAGG 1 chr3:138487096-138487176 ( 67) CCTGATGT 1 chr11:4015424-4015504 ( 48) TCACATGT 1 chr11:77526064-77526144 ( 31) ACTTCAGA 1 chr10:6515504-6515584 ( 32) ACAGATGG 1 chr10:58130654-58130734 ( 50) CCTCCTGT 1 chr1:234821938-234822018 ( 9) ACACATGT 1 chr1:95100717-95100797 ( 2) GCAGCTGG 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif WCWGCWGW MEME-1 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 8.31314 E= 1.2e-075 19 -111 -232 92 -1395 219 -1395 -1395 126 -1395 -1395 28 -1395 -111 190 -204 -38 185 -1395 -1395 46 -353 -1395 108 -1395 -1395 217 -1395 102 -1395 -232 50 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif WCWGCWGW MEME-1 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 158 E= 1.2e-075 0.310127 0.101266 0.044304 0.544304 0.000000 1.000000 0.000000 0.000000 0.651899 0.000000 0.000000 0.348101 0.000000 0.101266 0.829114 0.069620 0.208861 0.791139 0.000000 0.000000 0.373418 0.018987 0.000000 0.607595 0.000000 0.000000 1.000000 0.000000 0.550633 0.000000 0.044304 0.405063 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif WCWGCWGW MEME-1 regular expression -------------------------------------------------------------------------------- [TA]C[AT]G[CA][TA]G[AT] -------------------------------------------------------------------------------- Time 4.78 secs. ******************************************************************************** ******************************************************************************** MOTIF CCATTGTT MEME-2 width = 8 sites = 75 llr = 594 E-value = 2.5e-033 ******************************************************************************** -------------------------------------------------------------------------------- Motif CCATTGTT MEME-2 Description -------------------------------------------------------------------------------- Simplified A ::a:2::: pos.-specific C 9a:3::23 probability G ::::1a:: matrix T 1::78:87 bits 2.2 * * 2.0 * * 1.8 ** * 1.5 *** * Relative 1.3 *** * Entropy 1.1 *** *** (11.4 bits) 0.9 ******** 0.7 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel CCATTGTT consensus C CC sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCATTGTT MEME-2 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr18:3461176-3461256 41 1.96e-05 cttttggcct ccattgtt tctgatgaga chr8:8293280-8293360 31 1.96e-05 cttctgactt ccattgtt gctgtaaaga chr4:146433218-146433298 33 1.96e-05 cttctggttt ccattgtt tatgctgaaa chr6:157346771-157346851 31 1.96e-05 gagtcgtttt ccattgtt tggctatgat chr1:2578430-2578510 9 1.96e-05 tctgggtt ccattgtt tctgggacaa chr21:38774720-38774800 28 1.96e-05 cttctggctt ccattgtt tgtgatgaga chr1:166483459-166483539 24 1.96e-05 gcgatgtgtt ccattgtt ctctgactca chr7:154976769-154976849 16 1.96e-05 cctctagcca ccattgtt tctaatgaga chr20:61779031-61779111 6 1.96e-05 ggaat ccattgtt taaaacgaat chr10:75077155-75077235 7 1.96e-05 tggctt ccattgtt tcagatgaaa chr6:13942342-13942422 26 1.96e-05 cctctgtttt ccattgtt tttgttgaga chr1:54399986-54400066 20 1.96e-05 agatattgct ccattgtt gtctggcttc chr7:12741187-12741267 5 1.96e-05 gttt ccattgtt tttgttggga chr1:228386843-228386923 16 1.96e-05 ctcctggtat ccattgtt tccaatgaga chr3:43379894-43379974 19 1.96e-05 tttctggcat ccattgtt gctgttgaga chr9:132275690-132275770 16 1.96e-05 agatgccgtt ccattgtt tgctgacttt chr7:131021800-131021880 16 1.96e-05 cttctagctt ccattgtt tctgttgcaa chr2:146172886-146172966 14 3.46e-05 gtaagtcatt ccattgtc ttctggcttt chr20:36966215-36966295 1 3.46e-05 . CCATTGTC CTGTGTAGTC chr1:92868686-92868766 21 3.46e-05 agataccact ccattgtc ttctggcttg chr8:145838908-145838988 8 3.46e-05 cactaca ccattgtc ttcgcacttg chr8:23457948-23458028 3 3.46e-05 tt ccattgtc ttctagcctc chr4:185057815-185057895 4 3.46e-05 att ccattgtc tccttggatt chr1:200916329-200916409 17 4.96e-05 cttctgctct ccactgtt tctgtggaga chr5:125980995-125981075 23 4.96e-05 cttctggctg ccactgtt tcagctgaaa chr1:224359010-224359090 22 4.96e-05 cttctggcct ccactgtt tctcatgagg chr1:244739731-244739811 36 6.46e-05 ggtgctctcg ccattgct ccatctgcga chr1:63109120-63109200 13 6.46e-05 cttctggctt ccattgct gctgtgataa chr20:32535651-32535731 70 6.46e-05 ggctgcttgt ccattgct gcc chr5:77822962-77823042 17 6.46e-05 GTCACCATTT CCATTGCT GGCTCATGTC chr7:64869083-64869163 20 6.46e-05 atgacttacc ccattgct tagttcctct chr3:72274063-72274143 19 6.46e-05 ctctgatccc ccattgct tctggtggaa chr2:175057518-175057598 20 7.61e-05 aagtgtcatt ccactgtc tcctagcttc chr2:178342896-178342976 6 7.61e-05 tctca ccactgtc tgactttcat chr10:1024883-1024963 17 7.61e-05 tgaagatatt ccactgtc tcctgtctct chr3:14946701-14946781 4 7.61e-05 act ccactgtc ttctggtgta chr11:93708083-93708163 5 7.61e-05 tatt ccactgtc ttctagcttc chr2:44537584-44537664 15 1.06e-04 atatgtcatc ccattgcc ctctggcctt chr2:48575035-48575115 3 1.06e-04 tc ccatagtt tctggtgaga chr1:55109547-55109627 26 1.06e-04 cttttggcct ccatagtt tcagatgaga chr2:97043186-97043266 34 1.06e-04 cttctggctt ccatagtt tctgaagaaa chr16:58306897-58306977 12 1.06e-04 tcttttcagc ccattgcc ttctggcctt chr2:86977540-86977620 28 1.06e-04 tttctggcct ccatagtt tctgttgaga chr21:38721025-38721105 22 1.06e-04 tttatggctt ccatagtt ttgttgaaaa chr3:150393495-150393575 29 1.06e-04 tgaagacatt ccattgcc tttgagcctc chr1:91344973-91345053 23 1.06e-04 cttctgacct ccatagtt tctgaggata chr9:130285823-130285903 47 1.32e-04 GGTTGCCACA CCATAGTC AGCCACTAGG chr7:127835053-127835133 7 1.32e-04 gttgtt ccatagtc tcctcatcat chr3:98302754-98302834 67 1.70e-04 ATCTACTACC CCACAGTT CTGCCT chr4:160116710-160116790 30 1.70e-04 tgccaagctc ccactgcc taatgtggga chr10:94422756-94422836 44 1.70e-04 tttctggcct ccatggtt actgataaga chr19:7078179-7078259 38 1.70e-04 cttgcggcct ccatggtt tctggtgaca chr18:48488513-48488593 23 1.70e-04 atatgttatc ccactgcc ttctggcttt chr7:97726480-97726560 33 1.70e-04 cttctggcct ccatggtt tctgatgaaa chr11:76487669-76487749 1 1.70e-04 . ccactgcc ttctggcctc chr7:99536058-99536138 39 1.70e-04 cttctggcct ccatggtt ttgaggagat chr1:224531447-224531527 16 1.70e-04 cacctagcct ccatggtt tctgatgaga chr1:236544990-236545070 11 1.70e-04 aaaaatagct ccactgcc tcctgcctta chr10:82256439-82256519 7 1.84e-04 tagttt ccatagct ttgtcttcag chr10:103335818-10333589 5 2.32e-04 aaca ccacagtc attatctcac chr16:88609773-88609853 8 2.32e-04 ctgactc tcattgtt gatgaagagt chr12:23676409-23676489 13 2.32e-04 aattgtgatt tcattgtt tcttgattca chr2:113758157-113758237 16 2.32e-04 cttttggctt tcattgtt gtaattgaga chr20:36871404-36871484 33 2.75e-04 ctgtgcggga ccagtgtt caacagtgac chr6:18824156-18824236 48 2.75e-04 tgtgcaagaa ccagtgtt caacagcgcc chr7:24903950-24904030 17 3.28e-04 ccttgttaaa ccacagct cgttgggctc chr12:117566199-11756627 51 3.28e-04 acctgtcacg tcattgtc acctgtcacg chr9:132064369-132064449 66 3.56e-04 atatttcaag tcactgtt tggactg chr22:19304390-19304470 50 4.12e-04 caataacatc cccctgtt ctacctattg chr1:53603573-53603653 10 4.12e-04 ttagagggc cccctgtt tctgggatcc chr7:155441533-155441613 7 4.64e-04 tggctt ccatcgtt tctgatgaga chr1:207051967-207052047 26 4.88e-04 tgctgtaata tcactgtc ttggtggatt chr12:102090641-10209072 47 5.51e-04 TGACAGATGT CCCCTGTC CAAGTGAGTG chr8:127616241-127616321 42 5.51e-04 CCACGTGGTG GCACTGTT GACATGAGAc chr5:173019232-173019312 27 5.51e-04 ccacaaggtg gcactgtt gaacaccagt -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCATTGTT MEME-2 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr18:3461176-3461256 2e-05 40_[+2]_32 chr8:8293280-8293360 2e-05 30_[+2]_42 chr4:146433218-146433298 2e-05 32_[+2]_40 chr6:157346771-157346851 2e-05 30_[+2]_42 chr1:2578430-2578510 2e-05 8_[+2]_64 chr21:38774720-38774800 2e-05 27_[+2]_45 chr1:166483459-166483539 2e-05 23_[+2]_49 chr7:154976769-154976849 2e-05 15_[+2]_57 chr20:61779031-61779111 2e-05 5_[+2]_67 chr10:75077155-75077235 2e-05 6_[+2]_66 chr6:13942342-13942422 2e-05 25_[+2]_47 chr1:54399986-54400066 2e-05 19_[+2]_53 chr7:12741187-12741267 2e-05 4_[+2]_68 chr1:228386843-228386923 2e-05 15_[+2]_57 chr3:43379894-43379974 2e-05 18_[+2]_54 chr9:132275690-132275770 2e-05 15_[+2]_57 chr7:131021800-131021880 2e-05 15_[+2]_57 chr2:146172886-146172966 3.5e-05 13_[+2]_59 chr20:36966215-36966295 3.5e-05 [+2]_72 chr1:92868686-92868766 3.5e-05 20_[+2]_52 chr8:145838908-145838988 3.5e-05 7_[+2]_65 chr8:23457948-23458028 3.5e-05 2_[+2]_70 chr4:185057815-185057895 3.5e-05 3_[+2]_69 chr1:200916329-200916409 5e-05 16_[+2]_56 chr5:125980995-125981075 5e-05 22_[+2]_50 chr1:224359010-224359090 5e-05 21_[+2]_51 chr1:244739731-244739811 6.5e-05 35_[+2]_37 chr1:63109120-63109200 6.5e-05 12_[+2]_60 chr20:32535651-32535731 6.5e-05 69_[+2]_3 chr5:77822962-77823042 6.5e-05 16_[+2]_56 chr7:64869083-64869163 6.5e-05 19_[+2]_53 chr3:72274063-72274143 6.5e-05 18_[+2]_54 chr2:175057518-175057598 7.6e-05 19_[+2]_53 chr2:178342896-178342976 7.6e-05 5_[+2]_67 chr10:1024883-1024963 7.6e-05 16_[+2]_56 chr3:14946701-14946781 7.6e-05 3_[+2]_69 chr11:93708083-93708163 7.6e-05 4_[+2]_68 chr2:44537584-44537664 0.00011 14_[+2]_58 chr2:48575035-48575115 0.00011 2_[+2]_70 chr1:55109547-55109627 0.00011 25_[+2]_47 chr2:97043186-97043266 0.00011 33_[+2]_39 chr16:58306897-58306977 0.00011 11_[+2]_61 chr2:86977540-86977620 0.00011 27_[+2]_45 chr21:38721025-38721105 0.00011 21_[+2]_51 chr3:150393495-150393575 0.00011 28_[+2]_44 chr1:91344973-91345053 0.00011 22_[+2]_50 chr9:130285823-130285903 0.00013 46_[+2]_26 chr7:127835053-127835133 0.00013 6_[+2]_66 chr3:98302754-98302834 0.00017 66_[+2]_6 chr4:160116710-160116790 0.00017 29_[+2]_43 chr10:94422756-94422836 0.00017 43_[+2]_29 chr19:7078179-7078259 0.00017 37_[+2]_35 chr18:48488513-48488593 0.00017 22_[+2]_50 chr7:97726480-97726560 0.00017 32_[+2]_40 chr11:76487669-76487749 0.00017 [+2]_72 chr7:99536058-99536138 0.00017 38_[+2]_34 chr1:224531447-224531527 0.00017 15_[+2]_57 chr1:236544990-236545070 0.00017 10_[+2]_62 chr10:82256439-82256519 0.00018 6_[+2]_66 chr10:103335818-10333589 0.00023 4_[+2]_68 chr16:88609773-88609853 0.00023 7_[+2]_65 chr12:23676409-23676489 0.00023 12_[+2]_60 chr2:113758157-113758237 0.00023 15_[+2]_57 chr20:36871404-36871484 0.00027 32_[+2]_40 chr6:18824156-18824236 0.00027 47_[+2]_25 chr7:24903950-24904030 0.00033 16_[+2]_56 chr12:117566199-11756627 0.00033 50_[+2]_22 chr9:132064369-132064449 0.00036 65_[+2]_7 chr22:19304390-19304470 0.00041 49_[+2]_23 chr1:53603573-53603653 0.00041 9_[+2]_63 chr7:155441533-155441613 0.00046 6_[+2]_66 chr1:207051967-207052047 0.00049 25_[+2]_47 chr12:102090641-10209072 0.00055 46_[+2]_26 chr8:127616241-127616321 0.00055 41_[+2]_31 chr5:173019232-173019312 0.00055 26_[+2]_46 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCATTGTT MEME-2 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF CCATTGTT width=8 seqs=75 chr18:3461176-3461256 ( 41) CCATTGTT 1 chr8:8293280-8293360 ( 31) CCATTGTT 1 chr4:146433218-146433298 ( 33) CCATTGTT 1 chr6:157346771-157346851 ( 31) CCATTGTT 1 chr1:2578430-2578510 ( 9) CCATTGTT 1 chr21:38774720-38774800 ( 28) CCATTGTT 1 chr1:166483459-166483539 ( 24) CCATTGTT 1 chr7:154976769-154976849 ( 16) CCATTGTT 1 chr20:61779031-61779111 ( 6) CCATTGTT 1 chr10:75077155-75077235 ( 7) CCATTGTT 1 chr6:13942342-13942422 ( 26) CCATTGTT 1 chr1:54399986-54400066 ( 20) CCATTGTT 1 chr7:12741187-12741267 ( 5) CCATTGTT 1 chr1:228386843-228386923 ( 16) CCATTGTT 1 chr3:43379894-43379974 ( 19) CCATTGTT 1 chr9:132275690-132275770 ( 16) CCATTGTT 1 chr7:131021800-131021880 ( 16) CCATTGTT 1 chr2:146172886-146172966 ( 14) CCATTGTC 1 chr20:36966215-36966295 ( 1) CCATTGTC 1 chr1:92868686-92868766 ( 21) CCATTGTC 1 chr8:145838908-145838988 ( 8) CCATTGTC 1 chr8:23457948-23458028 ( 3) CCATTGTC 1 chr4:185057815-185057895 ( 4) CCATTGTC 1 chr1:200916329-200916409 ( 17) CCACTGTT 1 chr5:125980995-125981075 ( 23) CCACTGTT 1 chr1:224359010-224359090 ( 22) CCACTGTT 1 chr1:244739731-244739811 ( 36) CCATTGCT 1 chr1:63109120-63109200 ( 13) CCATTGCT 1 chr20:32535651-32535731 ( 70) CCATTGCT 1 chr5:77822962-77823042 ( 17) CCATTGCT 1 chr7:64869083-64869163 ( 20) CCATTGCT 1 chr3:72274063-72274143 ( 19) CCATTGCT 1 chr2:175057518-175057598 ( 20) CCACTGTC 1 chr2:178342896-178342976 ( 6) CCACTGTC 1 chr10:1024883-1024963 ( 17) CCACTGTC 1 chr3:14946701-14946781 ( 4) CCACTGTC 1 chr11:93708083-93708163 ( 5) CCACTGTC 1 chr2:44537584-44537664 ( 15) CCATTGCC 1 chr2:48575035-48575115 ( 3) CCATAGTT 1 chr1:55109547-55109627 ( 26) CCATAGTT 1 chr2:97043186-97043266 ( 34) CCATAGTT 1 chr16:58306897-58306977 ( 12) CCATTGCC 1 chr2:86977540-86977620 ( 28) CCATAGTT 1 chr21:38721025-38721105 ( 22) CCATAGTT 1 chr3:150393495-150393575 ( 29) CCATTGCC 1 chr1:91344973-91345053 ( 23) CCATAGTT 1 chr9:130285823-130285903 ( 47) CCATAGTC 1 chr7:127835053-127835133 ( 7) CCATAGTC 1 chr3:98302754-98302834 ( 67) CCACAGTT 1 chr4:160116710-160116790 ( 30) CCACTGCC 1 chr10:94422756-94422836 ( 44) CCATGGTT 1 chr19:7078179-7078259 ( 38) CCATGGTT 1 chr18:48488513-48488593 ( 23) CCACTGCC 1 chr7:97726480-97726560 ( 33) CCATGGTT 1 chr11:76487669-76487749 ( 1) CCACTGCC 1 chr7:99536058-99536138 ( 39) CCATGGTT 1 chr1:224531447-224531527 ( 16) CCATGGTT 1 chr1:236544990-236545070 ( 11) CCACTGCC 1 chr10:82256439-82256519 ( 7) CCATAGCT 1 chr10:103335818-10333589 ( 5) CCACAGTC 1 chr16:88609773-88609853 ( 8) TCATTGTT 1 chr12:23676409-23676489 ( 13) TCATTGTT 1 chr2:113758157-113758237 ( 16) TCATTGTT 1 chr20:36871404-36871484 ( 33) CCAGTGTT 1 chr6:18824156-18824236 ( 48) CCAGTGTT 1 chr7:24903950-24904030 ( 17) CCACAGCT 1 chr12:117566199-11756627 ( 51) TCATTGTC 1 chr9:132064369-132064449 ( 66) TCACTGTT 1 chr22:19304390-19304470 ( 50) CCCCTGTT 1 chr1:53603573-53603653 ( 10) CCCCTGTT 1 chr7:155441533-155441613 ( 7) CCATCGTT 1 chr1:207051967-207052047 ( 26) TCACTGTC 1 chr12:102090641-10209072 ( 47) CCCCTGTC 1 chr8:127616241-127616321 ( 42) GCACTGTT 1 chr5:173019232-173019312 ( 27) GCACTGTT 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCATTGTT MEME-2 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 8.10161 E= 2.5e-033 -1287 203 -305 -184 -1287 219 -1287 -1287 182 -245 -1287 -1287 -1287 42 -305 124 -77 -403 -173 140 -1287 -1287 217 -1287 -1287 -13 -1287 148 -1287 55 -1287 124 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCATTGTT MEME-2 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 75 E= 2.5e-033 0.000000 0.893333 0.026667 0.080000 0.000000 1.000000 0.000000 0.000000 0.960000 0.040000 0.000000 0.000000 0.000000 0.293333 0.026667 0.680000 0.160000 0.013333 0.066667 0.760000 0.000000 0.000000 1.000000 0.000000 0.000000 0.200000 0.000000 0.800000 0.000000 0.320000 0.000000 0.680000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCATTGTT MEME-2 regular expression -------------------------------------------------------------------------------- CCA[TC]TG[TC][TC] -------------------------------------------------------------------------------- Time 8.17 secs. ******************************************************************************** ******************************************************************************** MOTIF ACAATGGA MEME-3 width = 8 sites = 43 llr = 391 E-value = 6.8e-025 ******************************************************************************** -------------------------------------------------------------------------------- Motif ACAATGGA MEME-3 Description -------------------------------------------------------------------------------- Simplified A a:79:::a pos.-specific C :a1:::2: probability G :::1:a8: matrix T ::2:a::: bits 2.2 * * 2.0 ** * 1.8 ** ** * 1.5 ** **** Relative 1.3 ** ***** Entropy 1.1 ** ***** (13.1 bits) 0.9 ** ***** 0.7 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel ACAATGGA consensus T sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ACAATGGA MEME-3 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr3:33740970-33741050 58 1.70e-05 gagtaaggag acaatgga atgacattgt chr6:108563615-108563695 72 1.70e-05 ctcaccagaa acaatgga g chr6:106161567-106161647 55 1.70e-05 gaagccagag acaatgga aagacatcta chr19:55439853-55439933 48 1.70e-05 TCTATTGAAG ACAATGGA TGATGGTATT chr6:27282017-27282097 47 1.70e-05 ctcatgtgaa acaatgga ggccagaggc chr9:135572835-135572915 52 1.70e-05 atgtgagaag acaatgga aaggtgcctt chr5:10740665-10740745 52 1.70e-05 ctcgctgtac acaatgga agccagaaaa chr7:149408070-149408150 57 1.70e-05 aagtcaggag acaatgga ataaaatatt chr7:130940191-130940271 43 1.70e-05 ttctccaaga acaatgga tgccagaagg chr9:101223204-101223284 40 1.70e-05 ctcaatagaa acaatgga agccagaaga chr1:203064350-203064430 40 1.70e-05 aggccagaag acaatgga gcaacatctt chr19:19579397-19579477 40 1.70e-05 ctgactcgag acaatgga aacaaaaagg chr2:38966835-38966915 55 1.70e-05 ctcatctgga acaatgga gcccagaatg chr6:43924446-43924526 59 1.70e-05 cagatcagaa acaatgga ggccagaagg chr4:2134335-2134415 72 1.70e-05 agaccagaag acaatgga g chr20:33784292-33784372 69 1.70e-05 aagccagaag acaatgga ataa chr21:46242967-46243047 55 1.70e-05 aagccaggtg acaatgga attaacatct chr1:154268247-154268327 56 1.70e-05 ctcttcagaa acaatgga gaccaggagg chr7:50286333-50286413 62 1.70e-05 aaaccagaag acaatgga ataatatcac chr6:159326496-159326576 56 1.70e-05 ctcaacatta acaatgga agcaagaagt chr22:19636081-19636161 58 3.48e-05 ctcaccagaa actatgga ggccagaagg chr12:51193898-51193978 55 3.48e-05 ctcatcagaa actatgga ggtgagaaga chr7:92418052-92418132 47 3.48e-05 ctcatcagaa actatgga gggcagaagg chr2:43096172-43096252 68 3.48e-05 ctcaagtgaa actatgga ctcca chr1:243394321-243394401 35 3.48e-05 cttctcagaa actatgga gactagaaag chr2:112962154-112962234 43 3.48e-05 ctcatcagaa actatgga agccagaaga chr22:21094999-21095079 60 5.16e-05 ctctccagaa acaatgca agctactaga chr1:234821938-234822018 45 5.16e-05 ctcataggaa acaatgca agtgaaaaga chr4:88164728-88164808 24 6.52e-05 tttcacctaa accatgga agccagaaag chr7:18301867-18301947 61 6.52e-05 ctcttcagag accatgga ggttagaaga chr10:45991401-45991481 59 7.91e-05 gaggccagag acagtgga aggacataaa chr17:81090563-81090643 56 7.91e-05 cggccagaaa acagtgga atgctatgtt chr2:158579308-158579388 58 7.91e-05 aaatgaaaaa acagtgga acaacatatt chr7:2064976-2065056 32 7.91e-05 gagtcaaaag acagtgga atgataggtt chr1:197694357-197694437 71 7.91e-05 aagccagaag acagtgga at chr10:71309934-71310014 47 9.67e-05 ctcatcagaa actatgca agctggaaga chr2:127300854-127300934 28 9.67e-05 accttcagga actatgca agccagagga chr21:46248751-46248831 22 9.67e-05 gttagtagaa actatgca agccagaaga chr20:726500-726580 48 1.25e-04 ctcatgtgaa acgatgga ggccctaagg chr4:154449977-154450057 53 1.39e-04 TTCTTATCTG ACCATGCA CAGTGTATGG chr1:227530291-227530371 4 1.39e-04 CTG ACCATGCA ATATGCTACA chr9:138787202-138787282 4 1.65e-04 cat acaaggga acaccagctc chr6:18824156-18824236 22 1.94e-04 ctagcacagg acaatggt tactgggctg -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ACAATGGA MEME-3 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr3:33740970-33741050 1.7e-05 57_[+3]_15 chr6:108563615-108563695 1.7e-05 71_[+3]_1 chr6:106161567-106161647 1.7e-05 54_[+3]_18 chr19:55439853-55439933 1.7e-05 47_[+3]_25 chr6:27282017-27282097 1.7e-05 46_[+3]_26 chr9:135572835-135572915 1.7e-05 51_[+3]_21 chr5:10740665-10740745 1.7e-05 51_[+3]_21 chr7:149408070-149408150 1.7e-05 56_[+3]_16 chr7:130940191-130940271 1.7e-05 42_[+3]_30 chr9:101223204-101223284 1.7e-05 39_[+3]_33 chr1:203064350-203064430 1.7e-05 39_[+3]_33 chr19:19579397-19579477 1.7e-05 39_[+3]_33 chr2:38966835-38966915 1.7e-05 54_[+3]_18 chr6:43924446-43924526 1.7e-05 58_[+3]_14 chr4:2134335-2134415 1.7e-05 71_[+3]_1 chr20:33784292-33784372 1.7e-05 68_[+3]_4 chr21:46242967-46243047 1.7e-05 54_[+3]_18 chr1:154268247-154268327 1.7e-05 55_[+3]_17 chr7:50286333-50286413 1.7e-05 61_[+3]_11 chr6:159326496-159326576 1.7e-05 55_[+3]_17 chr22:19636081-19636161 3.5e-05 57_[+3]_15 chr12:51193898-51193978 3.5e-05 54_[+3]_18 chr7:92418052-92418132 3.5e-05 46_[+3]_26 chr2:43096172-43096252 3.5e-05 67_[+3]_5 chr1:243394321-243394401 3.5e-05 34_[+3]_38 chr2:112962154-112962234 3.5e-05 42_[+3]_30 chr22:21094999-21095079 5.2e-05 59_[+3]_13 chr1:234821938-234822018 5.2e-05 44_[+3]_28 chr4:88164728-88164808 6.5e-05 23_[+3]_49 chr7:18301867-18301947 6.5e-05 60_[+3]_12 chr10:45991401-45991481 7.9e-05 58_[+3]_14 chr17:81090563-81090643 7.9e-05 55_[+3]_17 chr2:158579308-158579388 7.9e-05 57_[+3]_15 chr7:2064976-2065056 7.9e-05 31_[+3]_41 chr1:197694357-197694437 7.9e-05 70_[+3]_2 chr10:71309934-71310014 9.7e-05 46_[+3]_26 chr2:127300854-127300934 9.7e-05 27_[+3]_45 chr21:46248751-46248831 9.7e-05 21_[+3]_51 chr20:726500-726580 0.00013 47_[+3]_25 chr4:154449977-154450057 0.00014 52_[+3]_20 chr1:227530291-227530371 0.00014 3_[+3]_69 chr9:138787202-138787282 0.00017 3_[+3]_69 chr6:18824156-18824236 0.00019 21_[+3]_51 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ACAATGGA MEME-3 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF ACAATGGA width=8 seqs=43 chr3:33740970-33741050 ( 58) ACAATGGA 1 chr6:108563615-108563695 ( 72) ACAATGGA 1 chr6:106161567-106161647 ( 55) ACAATGGA 1 chr19:55439853-55439933 ( 48) ACAATGGA 1 chr6:27282017-27282097 ( 47) ACAATGGA 1 chr9:135572835-135572915 ( 52) ACAATGGA 1 chr5:10740665-10740745 ( 52) ACAATGGA 1 chr7:149408070-149408150 ( 57) ACAATGGA 1 chr7:130940191-130940271 ( 43) ACAATGGA 1 chr9:101223204-101223284 ( 40) ACAATGGA 1 chr1:203064350-203064430 ( 40) ACAATGGA 1 chr19:19579397-19579477 ( 40) ACAATGGA 1 chr2:38966835-38966915 ( 55) ACAATGGA 1 chr6:43924446-43924526 ( 59) ACAATGGA 1 chr4:2134335-2134415 ( 72) ACAATGGA 1 chr20:33784292-33784372 ( 69) ACAATGGA 1 chr21:46242967-46243047 ( 55) ACAATGGA 1 chr1:154268247-154268327 ( 56) ACAATGGA 1 chr7:50286333-50286413 ( 62) ACAATGGA 1 chr6:159326496-159326576 ( 56) ACAATGGA 1 chr22:19636081-19636161 ( 58) ACTATGGA 1 chr12:51193898-51193978 ( 55) ACTATGGA 1 chr7:92418052-92418132 ( 47) ACTATGGA 1 chr2:43096172-43096252 ( 68) ACTATGGA 1 chr1:243394321-243394401 ( 35) ACTATGGA 1 chr2:112962154-112962234 ( 43) ACTATGGA 1 chr22:21094999-21095079 ( 60) ACAATGCA 1 chr1:234821938-234822018 ( 45) ACAATGCA 1 chr4:88164728-88164808 ( 24) ACCATGGA 1 chr7:18301867-18301947 ( 61) ACCATGGA 1 chr10:45991401-45991481 ( 59) ACAGTGGA 1 chr17:81090563-81090643 ( 56) ACAGTGGA 1 chr2:158579308-158579388 ( 58) ACAGTGGA 1 chr7:2064976-2065056 ( 32) ACAGTGGA 1 chr1:197694357-197694437 ( 71) ACAGTGGA 1 chr10:71309934-71310014 ( 47) ACTATGCA 1 chr2:127300854-127300934 ( 28) ACTATGCA 1 chr21:46248751-46248831 ( 22) ACTATGCA 1 chr20:726500-726580 ( 48) ACGATGGA 1 chr4:154449977-154450057 ( 53) ACCATGCA 1 chr1:227530291-227530371 ( 4) ACCATGCA 1 chr9:138787202-138787282 ( 4) ACAAGGGA 1 chr6:18824156-18824236 ( 22) ACAATGGT 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ACAATGGA MEME-3 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 9.73438 E= 6.8e-025 188 -1207 -1207 -1207 -1207 219 -1207 -1207 131 -123 -325 -46 170 -1207 -93 -1207 -1207 -1207 -325 176 -1207 -1207 217 -1207 -1207 -43 192 -1207 184 -1207 -1207 -362 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ACAATGGA MEME-3 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 43 E= 6.8e-025 1.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.674419 0.093023 0.023256 0.209302 0.883721 0.000000 0.116279 0.000000 0.000000 0.000000 0.023256 0.976744 0.000000 0.000000 1.000000 0.000000 0.000000 0.162791 0.837209 0.000000 0.976744 0.000000 0.000000 0.023256 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ACAATGGA MEME-3 regular expression -------------------------------------------------------------------------------- AC[AT]ATGGA -------------------------------------------------------------------------------- Time 11.41 secs. ******************************************************************************** ******************************************************************************** MOTIF GCCAGAAG MEME-4 width = 8 sites = 27 llr = 248 E-value = 4.7e-007 ******************************************************************************** -------------------------------------------------------------------------------- Motif GCCAGAAG MEME-4 Description -------------------------------------------------------------------------------- Simplified A 3::a:981 pos.-specific C :aa:1::: probability G 7:::9:29 matrix T :::::::: bits 2.2 * 2.0 *** 1.8 **** 1.5 ***** * Relative 1.3 ******** Entropy 1.1 ******** (13.3 bits) 0.9 ******** 0.7 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel GCCAGAAG consensus A sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GCCAGAAG MEME-4 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr22:19636081-19636161 67 1.06e-05 aactatggag gccagaag gaagtg chr9:126590944-126591024 56 1.06e-05 aacaatgtaa gccagaag acaatgagat chr11:87049241-87049321 59 1.06e-05 aacaataaag gccagaag gcaatgggat chr7:130940191-130940271 52 1.06e-05 aacaatggat gccagaag gcagtgggat chr9:101223204-101223284 49 1.06e-05 aacaatggaa gccagaag acaatggaat chr1:203064350-203064430 32 1.06e-05 tacaatgaag gccagaag acaatggagc chr6:43924446-43924526 68 1.06e-05 aacaatggag gccagaag gaggt chr20:33784292-33784372 61 1.06e-05 gaccatggaa gccagaag acaatggaat chr2:112962154-112962234 52 1.06e-05 aactatggaa gccagaag acagtgggag chr1:197694357-197694437 63 1.06e-05 agcaatggaa gccagaag acagtggaat chr2:127300854-127300934 37 3.21e-05 aactatgcaa gccagagg aaaatggagg chr6:27282017-27282097 56 3.21e-05 aacaatggag gccagagg cagtgggata chr8:2595612-2595692 43 3.21e-05 ctgatttctc accagaag caataggggc chr9:138787202-138787282 50 3.21e-05 agctatggag gccagagg gaagtggcac chr4:2134335-2134415 64 3.21e-05 gaccatgcag accagaag acaatggag chr2:6971541-6971621 18 3.21e-05 gagagtaaca accagaag gggacagcag chr7:50286333-50286413 54 3.21e-05 agtaatggaa accagaag acaatggaat chr17:81090563-81090643 48 5.55e-05 gacaatggcg gccagaaa acagtggaat chr5:10740665-10740745 61 5.55e-05 cacaatggaa gccagaaa aaaatggaat chr4:88164728-88164808 33 5.55e-05 aaccatggaa gccagaaa gcagtgggat chr4:151695363-151695443 17 6.60e-05 atcagttctg accagagg actctgtgac chr9:136462858-136462938 72 7.46e-05 gacaatgaga gccaggag a chr2:6985648-6985728 35 8.58e-05 atccagagga gccagtag ggcaggacta chr16:50705723-50705803 27 1.07e-04 tacagttttt accacaag gtgtcgctgt chr2:28378642-28378722 46 1.07e-04 ggggttatca gccacagg cagctcagtt chr5:173019232-173019312 16 1.07e-04 gcttctcttc accacaag gtggcactgt chr7:16384741-16384821 62 1.21e-04 agtcatggag gtcagaag gcagtggggg -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GCCAGAAG MEME-4 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr22:19636081-19636161 1.1e-05 66_[+4]_6 chr9:126590944-126591024 1.1e-05 55_[+4]_17 chr11:87049241-87049321 1.1e-05 58_[+4]_14 chr7:130940191-130940271 1.1e-05 51_[+4]_21 chr9:101223204-101223284 1.1e-05 48_[+4]_24 chr1:203064350-203064430 1.1e-05 31_[+4]_41 chr6:43924446-43924526 1.1e-05 67_[+4]_5 chr20:33784292-33784372 1.1e-05 60_[+4]_12 chr2:112962154-112962234 1.1e-05 51_[+4]_21 chr1:197694357-197694437 1.1e-05 62_[+4]_10 chr2:127300854-127300934 3.2e-05 36_[+4]_36 chr6:27282017-27282097 3.2e-05 55_[+4]_17 chr8:2595612-2595692 3.2e-05 42_[+4]_30 chr9:138787202-138787282 3.2e-05 49_[+4]_23 chr4:2134335-2134415 3.2e-05 63_[+4]_9 chr2:6971541-6971621 3.2e-05 17_[+4]_55 chr7:50286333-50286413 3.2e-05 53_[+4]_19 chr17:81090563-81090643 5.5e-05 47_[+4]_25 chr5:10740665-10740745 5.5e-05 60_[+4]_12 chr4:88164728-88164808 5.5e-05 32_[+4]_40 chr4:151695363-151695443 6.6e-05 16_[+4]_56 chr9:136462858-136462938 7.5e-05 71_[+4]_1 chr2:6985648-6985728 8.6e-05 34_[+4]_38 chr16:50705723-50705803 0.00011 26_[+4]_46 chr2:28378642-28378722 0.00011 45_[+4]_27 chr5:173019232-173019312 0.00011 15_[+4]_57 chr7:16384741-16384821 0.00012 61_[+4]_11 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GCCAGAAG MEME-4 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF GCCAGAAG width=8 seqs=27 chr22:19636081-19636161 ( 67) GCCAGAAG 1 chr9:126590944-126591024 ( 56) GCCAGAAG 1 chr11:87049241-87049321 ( 59) GCCAGAAG 1 chr7:130940191-130940271 ( 52) GCCAGAAG 1 chr9:101223204-101223284 ( 49) GCCAGAAG 1 chr1:203064350-203064430 ( 32) GCCAGAAG 1 chr6:43924446-43924526 ( 68) GCCAGAAG 1 chr20:33784292-33784372 ( 61) GCCAGAAG 1 chr2:112962154-112962234 ( 52) GCCAGAAG 1 chr1:197694357-197694437 ( 63) GCCAGAAG 1 chr2:127300854-127300934 ( 37) GCCAGAGG 1 chr6:27282017-27282097 ( 56) GCCAGAGG 1 chr8:2595612-2595692 ( 43) ACCAGAAG 1 chr9:138787202-138787282 ( 50) GCCAGAGG 1 chr4:2134335-2134415 ( 64) ACCAGAAG 1 chr2:6971541-6971621 ( 18) ACCAGAAG 1 chr7:50286333-50286413 ( 54) ACCAGAAG 1 chr17:81090563-81090643 ( 48) GCCAGAAA 1 chr5:10740665-10740745 ( 61) GCCAGAAA 1 chr4:88164728-88164808 ( 33) GCCAGAAA 1 chr4:151695363-151695443 ( 17) ACCAGAGG 1 chr9:136462858-136462938 ( 72) GCCAGGAG 1 chr2:6985648-6985728 ( 35) GCCAGTAG 1 chr16:50705723-50705803 ( 27) ACCACAAG 1 chr2:28378642-28378722 ( 46) GCCACAGG 1 chr5:173019232-173019312 ( 16) ACCACAAG 1 chr7:16384741-16384821 ( 62) GTCAGAAG 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GCCAGAAG MEME-4 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 9.9683 E= 4.7e-007 -7 -1140 174 -1140 -1140 214 -1140 -295 -1140 219 -1140 -1140 188 -1140 -1140 -1140 -1140 -98 200 -1140 177 -1140 -258 -295 158 -1140 -26 -1140 -129 -1140 200 -1140 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GCCAGAAG MEME-4 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 27 E= 4.7e-007 0.259259 0.000000 0.740741 0.000000 0.000000 0.962963 0.000000 0.037037 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.111111 0.888889 0.000000 0.925926 0.000000 0.037037 0.037037 0.814815 0.000000 0.185185 0.000000 0.111111 0.000000 0.888889 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GCCAGAAG MEME-4 regular expression -------------------------------------------------------------------------------- [GA]CCAGAAG -------------------------------------------------------------------------------- Time 14.60 secs. ******************************************************************************** ******************************************************************************** MOTIF TTCTGGCY MEME-5 width = 8 sites = 31 llr = 279 E-value = 4.7e-008 ******************************************************************************** -------------------------------------------------------------------------------- Motif TTCTGGCY MEME-5 Description -------------------------------------------------------------------------------- Simplified A :::::3:: pos.-specific C 21a:::a4 probability G ::::a7:: matrix T 89:a:::5 bits 2.2 * * * 2.0 * * * 1.8 *** * 1.5 *** * Relative 1.3 ****** Entropy 1.1 ******* (13.0 bits) 0.9 ******** 0.7 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel TTCTGGCT consensus A C sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTCTGGCY MEME-5 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr2:146172886-146172966 22 2.83e-05 ttccattgtc ttctggct ttcatgactc chr10:94422756-94422836 35 2.83e-05 tcctatggct ttctggcc tccatggtta chr8:144751382-144751462 65 2.83e-05 ccgctctctc ttctggcc actgggag chr1:92868686-92868766 29 2.83e-05 ctccattgtc ttctggct tgcatagctt chr1:63109120-63109200 4 2.83e-05 gtc ttctggct tccattgctg chr18:48488513-48488593 31 2.83e-05 tcccactgcc ttctggct ttcattgttt chr21:38774720-38774800 19 2.83e-05 ttccattgtc ttctggct tccattgttt chr2:97043186-97043266 25 2.83e-05 ttccaatgtc ttctggct tccatagttt chr5:125980995-125981075 14 2.83e-05 ttccactgcc ttctggct gccactgttt chr7:97726480-97726560 24 2.83e-05 tcccacaacc ttctggcc tccatggttt chr11:76487669-76487749 9 2.83e-05 ccactgcc ttctggcc tccaaagttt chr16:58306897-58306977 20 2.83e-05 gcccattgcc ttctggcc ttcattgttt chr2:86977540-86977620 19 2.83e-05 tgccacttct ttctggcc tccatagttt chr7:99536058-99536138 30 2.83e-05 ttccagtgtc ttctggcc tccatggttt chr5:154066221-154066301 43 2.83e-05 tactgtccct ttctggcT TTGGAGATGG chr1:224359010-224359090 13 2.83e-05 tcccactgcc ttctggcc tccactgttt chr2:44537584-44537664 23 4.98e-05 tcccattgcc ctctggcc ttcatggttt chrX:130086541-130086621 58 4.98e-05 tttgtcttat ctctggct aacaggtgtt chr19:44980912-44980992 20 4.98e-05 AAGAACATAA CTCTGGCT GAAGGATTTC chr3:39565752-39565832 8 8.45e-05 cattgtc ttctgacc tctataattg chr19:19579397-19579477 28 8.45e-05 aacagctgac ttctgact cgagacaatg chr1:114389407-114389487 1 8.45e-05 . ttctgacc tctatgattc chr2:25117762-25117842 47 8.45e-05 cttgaataat ttctgacc acacatctgc chr1:91344973-91345053 14 8.45e-05 tcacactgcc ttctgacc tccatagttt chr14:70107795-70107875 8 1.06e-04 cattgcc tcctggct tgcattattc chr5:148990519-148990599 56 1.06e-04 gctttgctga tcctggct gggttttttc chr6:158379253-158379333 6 1.06e-04 ttgtc tcctggct tgcatagttt chr2:180652424-180652504 55 1.33e-04 CATTCTAGGG CTCTGACT CTAAAGGAGC chr1:166483459-166483539 32 1.33e-04 ttccattgtt ctctgact cacatagttt chr20:61779031-61779111 58 1.33e-04 tgtccttttt ctctgact gcttttaaga chr3:43379894-43379974 10 1.48e-04 tccactgtt ttctggca tccattgttg -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTCTGGCY MEME-5 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr2:146172886-146172966 2.8e-05 21_[+5]_51 chr10:94422756-94422836 2.8e-05 34_[+5]_38 chr8:144751382-144751462 2.8e-05 64_[+5]_8 chr1:92868686-92868766 2.8e-05 28_[+5]_44 chr1:63109120-63109200 2.8e-05 3_[+5]_69 chr18:48488513-48488593 2.8e-05 30_[+5]_42 chr21:38774720-38774800 2.8e-05 18_[+5]_54 chr2:97043186-97043266 2.8e-05 24_[+5]_48 chr5:125980995-125981075 2.8e-05 13_[+5]_59 chr7:97726480-97726560 2.8e-05 23_[+5]_49 chr11:76487669-76487749 2.8e-05 8_[+5]_64 chr16:58306897-58306977 2.8e-05 19_[+5]_53 chr2:86977540-86977620 2.8e-05 18_[+5]_54 chr7:99536058-99536138 2.8e-05 29_[+5]_43 chr5:154066221-154066301 2.8e-05 42_[+5]_30 chr1:224359010-224359090 2.8e-05 12_[+5]_60 chr2:44537584-44537664 5e-05 22_[+5]_50 chrX:130086541-130086621 5e-05 57_[+5]_15 chr19:44980912-44980992 5e-05 19_[+5]_53 chr3:39565752-39565832 8.4e-05 7_[+5]_65 chr19:19579397-19579477 8.4e-05 27_[+5]_45 chr1:114389407-114389487 8.4e-05 [+5]_72 chr2:25117762-25117842 8.4e-05 46_[+5]_26 chr1:91344973-91345053 8.4e-05 13_[+5]_59 chr14:70107795-70107875 0.00011 7_[+5]_65 chr5:148990519-148990599 0.00011 55_[+5]_17 chr6:158379253-158379333 0.00011 5_[+5]_67 chr2:180652424-180652504 0.00013 54_[+5]_18 chr1:166483459-166483539 0.00013 31_[+5]_41 chr20:61779031-61779111 0.00013 57_[+5]_15 chr3:43379894-43379974 0.00015 9_[+5]_63 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTCTGGCY MEME-5 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF TTCTGGCY width=8 seqs=31 chr2:146172886-146172966 ( 22) TTCTGGCT 1 chr10:94422756-94422836 ( 35) TTCTGGCC 1 chr8:144751382-144751462 ( 65) TTCTGGCC 1 chr1:92868686-92868766 ( 29) TTCTGGCT 1 chr1:63109120-63109200 ( 4) TTCTGGCT 1 chr18:48488513-48488593 ( 31) TTCTGGCT 1 chr21:38774720-38774800 ( 19) TTCTGGCT 1 chr2:97043186-97043266 ( 25) TTCTGGCT 1 chr5:125980995-125981075 ( 14) TTCTGGCT 1 chr7:97726480-97726560 ( 24) TTCTGGCC 1 chr11:76487669-76487749 ( 9) TTCTGGCC 1 chr16:58306897-58306977 ( 20) TTCTGGCC 1 chr2:86977540-86977620 ( 19) TTCTGGCC 1 chr7:99536058-99536138 ( 30) TTCTGGCC 1 chr5:154066221-154066301 ( 43) TTCTGGCT 1 chr1:224359010-224359090 ( 13) TTCTGGCC 1 chr2:44537584-44537664 ( 23) CTCTGGCC 1 chrX:130086541-130086621 ( 58) CTCTGGCT 1 chr19:44980912-44980992 ( 20) CTCTGGCT 1 chr3:39565752-39565832 ( 8) TTCTGACC 1 chr19:19579397-19579477 ( 28) TTCTGACT 1 chr1:114389407-114389487 ( 1) TTCTGACC 1 chr2:25117762-25117842 ( 47) TTCTGACC 1 chr1:91344973-91345053 ( 14) TTCTGACC 1 chr14:70107795-70107875 ( 8) TCCTGGCT 1 chr5:148990519-148990599 ( 56) TCCTGGCT 1 chr6:158379253-158379333 ( 6) TCCTGGCT 1 chr2:180652424-180652504 ( 55) CTCTGACT 1 chr1:166483459-166483539 ( 32) CTCTGACT 1 chr20:61779031-61779111 ( 58) CTCTGACT 1 chr3:43379894-43379974 ( 10) TTCTGGCA 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTCTGGCY MEME-5 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 9.90618 E= 4.7e-008 -1160 -18 -1160 149 -1160 -118 -1160 165 -1160 219 -1160 -1160 -1160 -1160 -1160 180 -1160 -1160 217 -1160 -8 -1160 174 -1160 -1160 219 -1160 -1160 -307 94 -1160 93 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTCTGGCY MEME-5 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 31 E= 4.7e-008 0.000000 0.193548 0.000000 0.806452 0.000000 0.096774 0.000000 0.903226 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.258065 0.000000 0.741935 0.000000 0.000000 1.000000 0.000000 0.000000 0.032258 0.419355 0.000000 0.548387 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTCTGGCY MEME-5 regular expression -------------------------------------------------------------------------------- TTCTG[GA]C[TC] -------------------------------------------------------------------------------- Time 17.77 secs. ******************************************************************************** ******************************************************************************** SUMMARY OF MOTIFS ******************************************************************************** -------------------------------------------------------------------------------- Combined block diagrams: non-overlapping sites with p-value < 0.0001 -------------------------------------------------------------------------------- SEQUENCE NAME COMBINED P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr10:76576957-76577037 1.03e-01 80 chr6:159326496-159326576 8.84e-04 55_[+3(1.70e-05)]_17 chr1:197694357-197694437 1.16e-04 62_[+4(1.06e-05)]_[+3(7.91e-05)]_2 chr7:50286333-50286413 7.92e-06 23_[+1(5.69e-05)]_22_[+4(3.21e-05)]_\ [+3(1.70e-05)]_11 chr7:18301867-18301947 3.23e-03 39_[+1(5.69e-05)]_13_[+3(6.52e-05)]_\ 12 chr1:11817263-11817343 9.19e-02 80 chr1:236544990-236545070 1.39e-02 80 chr7:131021800-131021880 6.75e-03 15_[+2(1.96e-05)]_57 chr1:234821938-234822018 6.94e-02 44_[+3(5.16e-05)]_28 chr11:93708083-93708163 4.35e-03 4_[+2(7.61e-05)]_68 chr7:106677158-106677238 3.44e-02 80 chr4:88164728-88164808 6.55e-03 23_[+3(6.52e-05)]_1_[+4(5.55e-05)]_\ 40 chr9:132275690-132275770 1.11e-03 15_[+2(1.96e-05)]_57 chr7:65730737-65730817 1.58e-03 80 chr2:113758157-113758237 6.16e-02 80 chr2:6971541-6971621 1.79e-03 17_[+4(3.21e-05)]_55 chr3:43379894-43379974 1.20e-04 1_[+2(4.96e-05)]_9_[+2(1.96e-05)]_\ 12_[+1(2.96e-05)]_34 chr1:227530291-227530371 4.14e-03 28_[+1(7.21e-05)]_44 chr2:6985648-6985728 3.03e-02 34_[+4(8.58e-05)]_38 chr2:112962154-112962234 2.26e-04 42_[+3(3.48e-05)]_1_[+4(1.06e-05)]_\ 21 chr1:243394321-243394401 5.41e-03 34_[+3(3.48e-05)]_38 chr1:228386843-228386923 7.99e-04 15_[+2(1.96e-05)]_12_[+1(2.96e-05)]_\ 37 chr1:154268247-154268327 2.25e-03 55_[+3(1.70e-05)]_17 chr1:91344973-91345053 2.64e-04 13_[+5(8.45e-05)]_21_[+1(2.96e-05)]_\ 30 chr7:2064976-2065056 1.07e-01 31_[+3(7.91e-05)]_41 chr2:43096172-43096252 3.07e-02 67_[+3(3.48e-05)]_5 chr2:3400055-3400135 3.71e-02 80 chr11:4015424-4015504 1.99e-01 80 chr12:111742525-11174260 2.82e-01 80 chr7:12741187-12741267 2.49e-03 4_[+2(1.96e-05)]_12_[+1(2.96e-05)]_\ 48 chr3:14946701-14946781 1.48e-02 3_[+2(7.61e-05)]_69 chr7:99129090-99129170 6.63e-01 80 chr7:127835053-127835133 9.55e-03 43_[+1(2.96e-05)]_29 chr1:224359010-224359090 2.83e-04 12_[+5(2.83e-05)]_1_[+2(4.96e-05)]_\ 51 chr5:154066221-154066301 9.86e-02 42_[+5(2.83e-05)]_30 chr1:54399986-54400066 6.97e-05 19_[+2(1.96e-05)]_9_[+2(4.96e-05)]_\ 12_[+1(2.96e-05)]_16 chr5:134318122-134318202 3.06e-01 80 chr1:224531447-224531527 1.52e-03 35_[+1(2.96e-05)]_37 chr3:150393495-150393575 5.49e-02 80 chr3:72274063-72274143 2.07e-03 18_[+2(6.46e-05)]_12_[+1(2.96e-05)]_\ 34 chr7:149226354-149226434 1.10e-01 80 chr6:13942342-13942422 5.91e-02 25_[+2(1.96e-05)]_47 chr7:99536058-99536138 9.58e-05 29_[+5(2.83e-05)]_20_[+1(2.96e-05)]_\ 15 chr21:38721025-38721105 1.89e-03 40_[+1(2.96e-05)]_32 chr7:92418052-92418132 6.44e-03 46_[+3(3.48e-05)]_26 chr3:183371138-183371218 2.31e-01 80 chr10:1024883-1024963 7.72e-04 16_[+2(7.61e-05)]_29_[+1(2.96e-05)]_\ 19 chr21:46242967-46243047 2.44e-03 37_[+3(6.52e-05)]_9_[+3(1.70e-05)]_\ 18 chr2:86977540-86977620 2.39e-03 18_[+5(2.83e-05)]_54 chr2:25117762-25117842 6.04e-03 46_[+5(8.45e-05)]_26 chr5:173019232-173019312 3.10e-03 80 chr1:53603573-53603653 2.72e-01 80 chr20:33784292-33784372 4.36e-05 51_[+3(6.52e-05)]_1_[+4(1.06e-05)]_\ [+3(1.70e-05)]_4 chr3:196710245-196710325 4.50e-01 80 chr4:2134335-2134415 6.74e-05 63_[+4(3.21e-05)]_[+3(1.70e-05)]_1 chr16:58306897-58306977 9.13e-05 19_[+5(2.83e-05)]_21_[+1(2.96e-05)]_\ 24 chr7:35731729-35731809 4.78e-01 80 chr9:125702994-125703074 5.50e-02 80 chr10:75077155-75077235 9.11e-04 6_[+2(1.96e-05)]_66 chr6:18824156-18824236 2.25e-02 80 chr19:6292209-6292289 6.79e-01 80 chr1:114389407-114389487 1.35e-02 [+5(8.45e-05)]_72 chr6:43924446-43924526 1.60e-05 37_[+1(5.69e-05)]_13_[+3(1.70e-05)]_\ 1_[+4(1.06e-05)]_5 chr20:36871404-36871484 4.28e-02 80 chr2:158579308-158579388 1.88e-02 40_[+3(9.67e-05)]_9_[+3(7.91e-05)]_\ 15 chr14:103829314-10382939 2.38e-02 38_[+1(7.21e-05)]_34 chr15:67977564-67977644 4.39e-03 51_[+4(1.06e-05)]_21 chr9:101127651-101127731 4.12e-01 80 chr20:61779031-61779111 1.25e-04 5_[+2(1.96e-05)]_11_[+1(2.96e-05)]_\ 48 chr1:9589418-9589498 6.08e-02 80 chr21:46248751-46248831 4.63e-04 21_[+3(9.67e-05)]_1_[+4(1.06e-05)]_\ 42 chr1:117437856-117437936 8.05e-05 54_[+4(1.06e-05)]_[+3(1.70e-05)]_10 chr7:64869083-64869163 5.95e-02 19_[+2(6.46e-05)]_53 chr10:74397406-74397486 5.94e-02 80 chr21:46821123-46821203 1.42e-01 80 chr19:2933606-2933686 4.81e-01 80 chr2:38966835-38966915 9.24e-04 33_[+1(5.69e-05)]_13_[+3(1.70e-05)]_\ 18 chr22:19304390-19304470 2.07e-02 80 chr8:127288161-127288241 2.27e-02 80 chr11:76487669-76487749 2.30e-04 8_[+5(2.83e-05)]_21_[+1(7.21e-05)]_\ 35 chr6:158379253-158379333 5.45e-03 80 chr4:185057815-185057895 2.31e-03 3_[+2(3.46e-05)]_29_[+1(2.96e-05)]_\ 32 chr8:23457948-23458028 1.07e-03 2_[+2(3.46e-05)]_70 chr19:13211049-13211129 5.19e-01 80 chr7:99669127-99669207 4.30e-02 80 chr7:155441533-155441613 6.30e-02 80 chr19:19579397-19579477 9.96e-05 18_[+1(5.69e-05)]_1_[+5(8.45e-05)]_\ 4_[+3(1.70e-05)]_33 chr7:97726480-97726560 5.15e-05 23_[+5(2.83e-05)]_21_[+1(2.96e-05)]_\ 20 chr1:203064350-203064430 1.87e-04 31_[+4(1.06e-05)]_[+3(1.70e-05)]_33 chr5:125980995-125981075 1.72e-05 13_[+5(2.83e-05)]_1_[+2(4.96e-05)]_\ [+1(1.44e-05)]_42 chr18:77782822-77782902 2.10e-01 80 chr19:970793-970873 7.03e-02 80 chr9:101223204-101223284 4.11e-05 39_[+3(1.70e-05)]_1_[+4(1.06e-05)]_\ [+3(1.70e-05)]_16 chr7:130940191-130940271 3.03e-05 42_[+3(1.70e-05)]_1_[+4(1.06e-05)]_\ 21 chr20:726500-726580 1.49e-02 80 chr21:30568848-30568928 4.36e-01 80 chr4:95348091-95348171 2.20e-03 70_[+4(1.06e-05)]_2 chr7:149163628-149163708 2.05e-04 23_[+2(3.46e-05)]_[+5(8.45e-05)]_41 chr3:138487096-138487176 2.37e-01 80 chr7:154976769-154976849 8.14e-03 15_[+2(1.96e-05)]_57 chr7:149408070-149408150 7.01e-04 56_[+3(1.70e-05)]_16 chr12:23676409-23676489 1.38e-02 48_[+1(2.96e-05)]_24 chr7:86957784-86957864 9.31e-02 80 chr10:5432710-5432790 1.14e-01 46_[+1(5.69e-05)]_26 chr9:138787202-138787282 2.88e-04 49_[+4(3.21e-05)]_23 chr8:2595612-2595692 1.64e-03 28_[+1(5.69e-05)]_6_[+4(3.21e-05)]_\ 30 chr5:148990519-148990599 1.09e-02 80 chr1:29706121-29706201 4.96e-01 80 chr2:97043186-97043266 9.48e-04 24_[+5(2.83e-05)]_48 chr5:10740665-10740745 5.44e-04 51_[+3(1.70e-05)]_1_[+4(5.55e-05)]_\ 12 chr7:156526536-156526616 1.87e-01 80 chr10:5207852-5207932 5.97e-01 80 chr1:95100717-95100797 1.60e-01 80 chr4:25052511-25052591 1.15e-01 80 chr22:23012707-23012787 3.39e-01 80 chr1:166483459-166483539 4.24e-03 23_[+2(1.96e-05)]_49 chr5:77822962-77823042 1.08e-03 16_[+2(6.46e-05)]_56 chr9:135572835-135572915 3.34e-02 51_[+3(1.70e-05)]_21 chr20:32535651-32535731 1.48e-02 69_[+2(6.46e-05)]_3 chr6:27282017-27282097 1.61e-04 46_[+3(1.70e-05)]_1_[+4(3.21e-05)]_\ 17 chr16:88609773-88609853 1.24e-02 27_[+1(2.96e-05)]_45 chr19:12638392-12638472 1.17e-01 80 chr2:178342896-178342976 1.07e-03 5_[+2(7.61e-05)]_14_[+1(7.21e-05)]_\ 4_[+1(2.96e-05)]_33 chr19:55439853-55439933 1.46e-03 47_[+3(1.70e-05)]_25 chr1:55109547-55109627 3.03e-03 80 chr21:38774720-38774800 8.95e-04 10_[+2(3.46e-05)]_[+5(2.83e-05)]_1_\ [+2(1.96e-05)]_45 chr1:207051967-207052047 6.80e-03 80 chr18:48488513-48488593 3.99e-04 30_[+5(2.83e-05)]_9_[+1(7.21e-05)]_\ 25 chr9:132064369-132064449 5.60e-03 80 chr2:48575035-48575115 6.67e-03 80 chr8:145838908-145838988 4.25e-03 7_[+2(3.46e-05)]_65 chr12:132678761-13267884 3.77e-02 80 chr6:74238827-74238907 1.47e-01 80 chr1:2578430-2578510 2.34e-03 8_[+2(1.96e-05)]_64 chr6:106161567-106161647 1.74e-04 54_[+3(1.70e-05)]_18 chr10:82256439-82256519 2.36e-01 80 chr17:48217483-48217563 6.51e-02 48_[+1(7.21e-05)]_24 chr2:127300854-127300934 1.31e-04 6_[+1(5.69e-05)]_13_[+3(9.67e-05)]_\ 1_[+4(3.21e-05)]_36 chr6:35662357-35662437 2.26e-02 80 chr1:237079672-237079752 4.34e-02 68_[+4(3.21e-05)]_4 chr17:81090563-81090643 1.02e-02 47_[+4(5.55e-05)]_[+3(7.91e-05)]_17 chr19:7083153-7083233 3.40e-01 80 chr19:9676726-9676806 3.69e-01 80 chr1:70005887-70005967 1.98e-01 80 chr6:163929132-163929212 4.95e-01 80 chr8:125959300-125959380 9.28e-03 46_[+1(5.69e-05)]_26 chr19:58708513-58708593 3.74e-01 80 chr11:17393341-17393421 6.21e-01 80 chr1:226169539-226169619 1.97e-01 80 chr1:63109120-63109200 8.43e-05 3_[+5(2.83e-05)]_1_[+2(6.46e-05)]_\ 11_[+1(2.96e-05)]_41 chr2:28378642-28378722 3.65e-02 80 chr19:44980912-44980992 2.95e-02 19_[+5(4.98e-05)]_53 chr11:77526064-77526144 1.61e-01 80 chr1:32860290-32860370 1.20e-01 80 chr6:119217817-119217897 8.29e-01 80 chr7:128523733-128523813 2.05e-01 80 chr7:138212543-138212623 1.98e-01 80 chr6:24431410-24431490 3.99e-02 80 chr9:136462858-136462938 4.98e-04 71_[+4(7.46e-05)]_1 chr5:121462211-121462291 1.33e-01 80 chr11:82503018-82503098 4.34e-01 80 chr4:151695363-151695443 1.02e-03 16_[+4(6.60e-05)]_56 chr11:87049241-87049321 4.89e-04 28_[+1(5.69e-05)]_22_[+4(1.06e-05)]_\ 14 chr22:21094999-21095079 1.35e-02 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chr10:45991401-45991481 3.10e-04 21_[+1(5.69e-05)]_29_[+3(7.91e-05)]_\ 14 chr6:20575564-20575644 6.34e-02 80 chr10:103335818-10333589 6.22e-04 72_[+1(5.69e-05)] chr8:144751382-144751462 5.96e-04 64_[+5(2.83e-05)]_8 chr10:6515504-6515584 6.05e-01 80 chr3:143002392-143002472 2.71e-01 80 chr9:125016696-125016776 1.17e-01 80 chr6:157811396-157811476 6.36e-01 80 chr10:94422756-94422836 3.99e-05 34_[+5(2.83e-05)]_21_[+1(2.96e-05)]_\ 9 chr6:157927071-157927151 6.17e-01 80 chr2:54304740-54304820 5.78e-01 80 chr1:168421748-168421828 3.82e-01 80 chr7:138114456-138114536 4.78e-03 80 chr18:3461176-3461256 2.56e-04 40_[+2(1.96e-05)]_12_[+1(2.96e-05)]_\ 12 chr4:160116710-160116790 2.50e-01 80 chr7:16779997-16780077 6.84e-02 80 chr1:192946629-192946709 3.52e-01 80 chr7:5123150-5123230 1.01e-02 80 chr12:90072118-90072198 5.22e-01 80 chr3:33740970-33741050 2.09e-04 57_[+3(1.70e-05)]_15 chr4:25225524-25225604 8.92e-02 80 chr12:127661495-12766157 1.80e-01 80 chr9:72046808-72046888 5.15e-02 80 chr3:98302754-98302834 7.26e-03 80 chr9:130285823-130285903 9.68e-03 80 chr14:70107795-70107875 5.69e-03 80 chr1:57684554-57684634 1.65e-02 80 chr4:95471626-95471706 4.07e-01 80 chr5:178110968-178111048 4.33e-02 80 chr4:103277050-103277130 2.98e-01 80 chr1:244739731-244739811 1.36e-03 35_[+2(6.46e-05)]_37 chr2:146172886-146172966 1.04e-04 13_[+2(3.46e-05)]_[+5(2.83e-05)]_51 chr10:5561150-5561230 9.04e-01 80 chrX:130086541-130086621 1.90e-02 57_[+5(4.98e-05)]_15 chr10:127293930-12729401 7.41e-01 80 chr10:11183687-11183767 3.60e-01 80 chr3:105333298-105333378 5.43e-01 80 chr5:180301065-180301145 9.12e-01 80 chr1:200916329-200916409 3.27e-02 16_[+2(4.96e-05)]_56 chr2:44537584-44537664 6.32e-03 22_[+5(4.98e-05)]_50 chr16:8688291-8688371 1.18e-01 80 chr6:80314372-80314452 4.47e-01 80 -------------------------------------------------------------------------------- ******************************************************************************** ******************************************************************************** Stopped because requested number of motifs (5) found. ******************************************************************************** CPU: c17n09.farnam.hpc.yale.internal ********************************************************************************