******************************************************************************** MEME - Motif discovery tool ******************************************************************************** MEME version 5.3.3 (Release date: Sun Feb 7 15:39:52 2021 -0800) For further information on how to interpret these results please access https://meme-suite.org/meme. To get a copy of the MEME Suite software please access https://meme-suite.org. ******************************************************************************** ******************************************************************************** REFERENCE ******************************************************************************** If you use this program in your research, please cite: Timothy L. Bailey and Charles Elkan, "Fitting a mixture model by expectation maximization to discover motifs in biopolymers", Proceedings of the Second International Conference on Intelligent Systems for Molecular Biology, pp. 28-36, AAAI Press, Menlo Park, California, 1994. ******************************************************************************** ******************************************************************************** TRAINING SET ******************************************************************************** PRIMARY SEQUENCES= ../result/final_prediction/K562/fasta/RankLinear0.6_40/THRA.fasta CONTROL SEQUENCES= --none-- ALPHABET= ACGT Sequence name Weight Length Sequence name Weight Length ------------- ------ ------ ------------- ------ ------ chr22:50327878-50327958 1.0000 80 chr19:10426988-10427068 1.0000 80 chr20:23161397-23161477 1.0000 80 chr1:25543630-25543710 1.0000 80 chr4:139867604-139867684 1.0000 80 chrX:39992201-39992281 1.0000 80 chr22:38077793-38077873 1.0000 80 chr6:16241744-16241824 1.0000 80 chr5:146345813-146345893 1.0000 80 chr10:99503356-99503436 1.0000 80 chr15:68190143-68190223 1.0000 80 chr7:55640628-55640708 1.0000 80 chr17:7739613-7739693 1.0000 80 chr6:47215031-47215111 1.0000 80 chr6:83716223-83716303 1.0000 80 chr17:62832862-62832942 1.0000 80 chr3:6686419-6686499 1.0000 80 chr11:63712601-63712681 1.0000 80 chr6:17966222-17966302 1.0000 80 chr1:14136400-14136480 1.0000 80 chr16:11892392-11892472 1.0000 80 chr12:117507404-11750748 1.0000 80 chr4:7034261-7034341 1.0000 80 chr22:17518847-17518927 1.0000 80 chr4:174363892-174363972 1.0000 80 chr19:2168289-2168369 1.0000 80 chr4:174968777-174968857 1.0000 80 chr16:28608342-28608422 1.0000 80 chr4:185668249-185668329 1.0000 80 chrX:71933570-71933650 1.0000 80 chr2:191272512-191272592 1.0000 80 chr20:23641150-23641230 1.0000 80 chr6:26155980-26156060 1.0000 80 chr8:41670720-41670800 1.0000 80 chr6:144851391-144851471 1.0000 80 chr18:8610444-8610524 1.0000 80 chr12:118726183-11872626 1.0000 80 chr22:50701532-50701612 1.0000 80 chr1:25605005-25605085 1.0000 80 chr5:6544097-6544177 1.0000 80 chr11:76572841-76572921 1.0000 80 chr6:34663363-34663443 1.0000 80 chr5:135524770-135524850 1.0000 80 chr6:107443358-107443438 1.0000 80 chr20:33126639-33126719 1.0000 80 chr17:34193586-34193666 1.0000 80 chr3:195951289-195951369 1.0000 80 chr6:10489424-10489504 1.0000 80 chr19:45245754-45245834 1.0000 80 chr19:34753366-34753446 1.0000 80 chr1:246536048-246536128 1.0000 80 chr20:22567512-22567592 1.0000 80 chr11:96012954-96013034 1.0000 80 chr19:8439160-8439240 1.0000 80 chr9:73035192-73035272 1.0000 80 chr2:46525661-46525741 1.0000 80 chr12:25428870-25428950 1.0000 80 chr2:232046798-232046878 1.0000 80 chr3:112532046-112532126 1.0000 80 chr20:23095847-23095927 1.0000 80 chrX:2451529-2451609 1.0000 80 chr1:183462912-183462992 1.0000 80 chr11:34621306-34621386 1.0000 80 chr14:102094864-10209494 1.0000 80 chr8:117557410-117557490 1.0000 80 chr5:81069545-81069625 1.0000 80 chr19:7957489-7957569 1.0000 80 chr22:46402457-46402537 1.0000 80 chr20:32418321-32418401 1.0000 80 chr6:167177693-167177773 1.0000 80 chr1:166668134-166668214 1.0000 80 chr10:102823664-10282374 1.0000 80 chr8:105542641-105542721 1.0000 80 chr9:36573687-36573767 1.0000 80 chr9:97788185-97788265 1.0000 80 chr3:177315739-177315819 1.0000 80 chr2:65449181-65449261 1.0000 80 chr9:134188580-134188660 1.0000 80 chrX:154365885-154365965 1.0000 80 chr13:95948799-95948879 1.0000 80 chr12:67949353-67949433 1.0000 80 chr19:8488109-8488189 1.0000 80 chr15:40430148-40430228 1.0000 80 chr2:10148707-10148787 1.0000 80 chr6:35778949-35779029 1.0000 80 chr4:83332210-83332290 1.0000 80 chr12:56661358-56661438 1.0000 80 chr3:49481573-49481653 1.0000 80 chr9:93949239-93949319 1.0000 80 chr1:227581236-227581316 1.0000 80 chr5:180588657-180588737 1.0000 80 chr16:47181139-47181219 1.0000 80 chr4:6809524-6809604 1.0000 80 chrX:65709282-65709362 1.0000 80 chr11:62728619-62728699 1.0000 80 chr16:21275686-21275766 1.0000 80 chr17:1696846-1696926 1.0000 80 chr9:86602174-86602254 1.0000 80 chr8:56765328-56765408 1.0000 80 chr5:56738385-56738465 1.0000 80 chr4:57378473-57378553 1.0000 80 chr10:65181538-65181618 1.0000 80 chr22:41213187-41213267 1.0000 80 chr15:51964720-51964800 1.0000 80 chr3:195581248-195581328 1.0000 80 chr22:43560102-43560182 1.0000 80 chr6:15491811-15491891 1.0000 80 chr11:18032884-18032964 1.0000 80 chr3:58950000-58950080 1.0000 80 chr19:55193983-55194063 1.0000 80 chr2:196996190-196996270 1.0000 80 chr2:170408187-170408267 1.0000 80 chr8:128876448-128876528 1.0000 80 chr9:14538689-14538769 1.0000 80 chr11:47961353-47961433 1.0000 80 chr19:3986358-3986438 1.0000 80 chr5:130943429-130943509 1.0000 80 chr2:114361131-114361211 1.0000 80 chr3:15404182-15404262 1.0000 80 chr4:68579994-68580074 1.0000 80 chr20:19983387-19983467 1.0000 80 chr11:5249089-5249169 1.0000 80 chr6:43464519-43464599 1.0000 80 chr1:40121420-40121500 1.0000 80 chr6:11093490-11093570 1.0000 80 chr3:14416863-14416943 1.0000 80 chr3:177051983-177052063 1.0000 80 chr4:169937255-169937335 1.0000 80 chr16:84076922-84077002 1.0000 80 chr2:114649712-114649792 1.0000 80 chr17:71027894-71027974 1.0000 80 chr3:171679313-171679393 1.0000 80 chr15:49271002-49271082 1.0000 80 chr17:7197341-7197421 1.0000 80 chr19:51568014-51568094 1.0000 80 chr7:140020068-140020148 1.0000 80 chr7:8273158-8273238 1.0000 80 chr17:60258289-60258369 1.0000 80 chr12:5330165-5330245 1.0000 80 chr9:73034183-73034263 1.0000 80 chr2:178544693-178544773 1.0000 80 chr19:45429675-45429755 1.0000 80 chr16:9221554-9221634 1.0000 80 chr1:15501232-15501312 1.0000 80 chr12:23208130-23208210 1.0000 80 chr6:26012519-26012599 1.0000 80 chr9:127704312-127704392 1.0000 80 chr6:126245541-126245621 1.0000 80 chr2:103352300-103352380 1.0000 80 chr1:52830937-52831017 1.0000 80 chr1:211546006-211546086 1.0000 80 chr3:172259239-172259319 1.0000 80 chr5:86405756-86405836 1.0000 80 chr2:9835792-9835872 1.0000 80 chr11:75186750-75186830 1.0000 80 chr11:68103313-68103393 1.0000 80 chr5:118656359-118656439 1.0000 80 chr6:14454314-14454394 1.0000 80 chr17:18075988-18076068 1.0000 80 chr2:24846603-24846683 1.0000 80 chr11:46736121-46736201 1.0000 80 chr12:29408165-29408245 1.0000 80 chr9:133397833-133397913 1.0000 80 chr6:90049500-90049580 1.0000 80 chr21:47368809-47368889 1.0000 80 chr7:76000322-76000402 1.0000 80 chr22:22920894-22920974 1.0000 80 chr12:110368653-11036873 1.0000 80 chr2:178151091-178151171 1.0000 80 chr2:9940131-9940211 1.0000 80 chr13:22583716-22583796 1.0000 80 chr17:38668524-38668604 1.0000 80 chr2:205299509-205299589 1.0000 80 chr20:33292560-33292640 1.0000 80 chr20:52407724-52407804 1.0000 80 chr5:34673740-34673820 1.0000 80 chr16:27482267-27482347 1.0000 80 chr12:96866469-96866549 1.0000 80 chr11:113568663-11356874 1.0000 80 chr1:23977848-23977928 1.0000 80 chr10:62535555-62535635 1.0000 80 chr4:6705718-6705798 1.0000 80 chr2:114665019-114665099 1.0000 80 chr19:35879744-35879824 1.0000 80 chr2:74304837-74304917 1.0000 80 chr2:216164340-216164420 1.0000 80 chr12:6480428-6480508 1.0000 80 chr3:37684900-37684980 1.0000 80 chr7:140375287-140375367 1.0000 80 chr17:73298069-73298149 1.0000 80 chr17:55131468-55131548 1.0000 80 chr22:41959216-41959296 1.0000 80 chr12:49657293-49657373 1.0000 80 chr6:14691379-14691459 1.0000 80 chr3:169850325-169850405 1.0000 80 chr10:6076115-6076195 1.0000 80 chr1:184715064-184715144 1.0000 80 chr2:132419615-132419695 1.0000 80 chr3:50628467-50628547 1.0000 80 chr10:1851459-1851539 1.0000 80 chr1:28116138-28116218 1.0000 80 chr3:71419511-71419591 1.0000 80 chr16:75612354-75612434 1.0000 80 chr1:225633225-225633305 1.0000 80 chr15:52970893-52970973 1.0000 80 chr20:47547498-47547578 1.0000 80 chr8:68989780-68989860 1.0000 80 chr21:46256574-46256654 1.0000 80 chr16:74876454-74876534 1.0000 80 chr7:2996266-2996346 1.0000 80 chr10:43119610-43119690 1.0000 80 chr19:14618750-14618830 1.0000 80 chr1:90288700-90288780 1.0000 80 chr17:8198989-8199069 1.0000 80 chr18:616504-616584 1.0000 80 chr2:225350110-225350190 1.0000 80 chr1:235053437-235053517 1.0000 80 chr2:74198310-74198390 1.0000 80 chr6:10315025-10315105 1.0000 80 chr11:86714163-86714243 1.0000 80 chr5:96382082-96382162 1.0000 80 chr6:41978189-41978269 1.0000 80 chr7:135629646-135629726 1.0000 80 chr19:45417108-45417188 1.0000 80 chr17:57862775-57862855 1.0000 80 chr16:20927201-20927281 1.0000 80 chr9:98637292-98637372 1.0000 80 chr6:15033556-15033636 1.0000 80 chr13:60832661-60832741 1.0000 80 chr3:72067678-72067758 1.0000 80 chr4:140135399-140135479 1.0000 80 chr7:106424691-106424771 1.0000 80 chr3:148803951-148804031 1.0000 80 chr1:161347043-161347123 1.0000 80 chr4:40918992-40919072 1.0000 80 chr16:46782320-46782400 1.0000 80 chr2:62422806-62422886 1.0000 80 chr22:22391808-22391888 1.0000 80 chr1:206592852-206592932 1.0000 80 chrX:118603425-118603505 1.0000 80 chr11:119312115-11931219 1.0000 80 chr20:39636874-39636954 1.0000 80 chr3:170530961-170531041 1.0000 80 chr11:46231747-46231827 1.0000 80 chr2:172078322-172078402 1.0000 80 chr22:50607371-50607451 1.0000 80 chr1:28276703-28276783 1.0000 80 chr7:66691561-66691641 1.0000 80 chr22:23319307-23319387 1.0000 80 chr16:49654594-49654674 1.0000 80 ******************************************************************************** ******************************************************************************** COMMAND LINE SUMMARY ******************************************************************************** This information can also be useful in the event you wish to report a problem with the MEME software. command: meme -oc ../result/final_prediction/K562/inference_raw/MEME/RankLinear0.6_40_THRA/ -dna -nmotifs 5 -w 8 -maxsize 250000 -nostatus ../result/final_prediction/K562/fasta/RankLinear0.6_40/THRA.fasta model: mod= zoops nmotifs= 5 evt= inf objective function: em= E-value of product of p-values starts= E-value of product of p-values strands: + width: minw= 8 maxw= 8 nsites: minsites= 2 maxsites= 250 wnsites= 0.8 theta: spmap= uni spfuzz= 0.5 em: prior= dirichlet b= 0.01 maxiter= 50 distance= 1e-05 trim: wg= 11 ws= 1 endgaps= yes data: n= 20000 N= 250 sample: seed= 0 hsfrac= 0 searchsize= 20000 norand= no csites= 1000 Letter frequencies in dataset: A 0.235 C 0.262 G 0.261 T 0.241 Background letter frequencies (from file dataset with add-one prior applied): A 0.235 C 0.262 G 0.261 T 0.242 Background model order: 0 ******************************************************************************** ******************************************************************************** MOTIF TGASSTCA MEME-1 width = 8 sites = 170 llr = 1192 E-value = 9.2e-110 ******************************************************************************** -------------------------------------------------------------------------------- Motif TGASSTCA MEME-1 Description -------------------------------------------------------------------------------- Simplified A ::6::2:a pos.-specific C :::5518: probability G :9154:1: matrix T a:3::71: bits 2.1 * * 1.9 * * 1.7 * * 1.5 ** * Relative 1.3 ** ** Entropy 1.0 ** *** (10.1 bits) 0.8 **** *** 0.6 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel TGACCTCA consensus TGG sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGASSTCA MEME-1 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr22:22391808-22391888 64 3.03e-05 CAGGCCTTGC TGACCTCA GAAGTTTCA chr6:15033556-15033636 27 3.03e-05 cacacccttg tgacctca tttaacctta chr2:74198310-74198390 17 3.03e-05 GCCCTGAACT TGACCTCA GATGACCTGC chr19:14618750-14618830 22 3.03e-05 ATGTAGTTGG TGACCTCA AGGGAACTCA chr1:225633225-225633305 50 3.03e-05 ctgaaactcc tgacctca gatgacctgc chr16:75612354-75612434 41 3.03e-05 ctcaaactcc tgacctca ggtgacccac chr6:14691379-14691459 63 3.03e-05 cttgaactcc tgacctca ggtgacctgc chr12:49657293-49657373 45 3.03e-05 cttgaactcc tgacctca agtgacctgc chr11:46736121-46736201 17 3.03e-05 ttcaaactcc tgacctca agtgatctgc chr11:68103313-68103393 18 3.03e-05 tggcctcagt tgacctca gtttggaacg chr11:75186750-75186830 9 3.03e-05 ACCTGAGG TGAGCTCA GCCCTTTCTG chr2:9835792-9835872 53 3.03e-05 ctcaaactcc tgacctca ggtgacccac chr9:86602174-86602254 21 3.03e-05 ctcacactcc tgacctca gatgatccac chr5:180588657-180588737 57 3.03e-05 TTTGTCCAAC TGACCTCA GAGGCCCCCT chr19:8488109-8488189 62 3.03e-05 gctggtctcc tgacctca gatgacccac chr12:67949353-67949433 11 3.03e-05 cgtcctaggt tgacctca gactgctgtg chrX:154365885-154365965 22 3.03e-05 tcggaactcc tgacctca ggtgatccgc chr1:183462912-183462992 30 3.03e-05 ctcgaatgcc tgacctca ggtgatctgc chr20:23095847-23095927 25 3.03e-05 tgtgaactgc tgacctca aatgaccctc chr3:112532046-112532126 56 3.03e-05 TGTCCTCAGA TGACCTCA TGAAATGTAG chr19:34753366-34753446 62 3.03e-05 ctggaactcc tgacctca ggtgatccgc chr1:25605005-25605085 39 3.03e-05 tggcctcaga tgacctca ttcacgtgtt chr18:8610444-8610524 73 3.03e-05 TATTTATCCA TGACCTCA chr4:185668249-185668329 34 3.03e-05 GCCAGTGTCC TGACCTCA GGAGCCCTTA chr17:57862775-57862855 43 6.05e-05 gtggatcatt tgaggtca ggggctaaag chr8:68989780-68989860 6 6.05e-05 TGCAG TGAGGTCA TTTAGGGATG chr20:47547498-47547578 23 6.05e-05 aatttgagag tgaggtca gtaaggtgaa chr11:113568663-11356874 42 6.05e-05 taaggttaaa tgaggtca cgagggtgac chr12:96866469-96866549 7 6.05e-05 gtcacc tgaggtca ggagttcggg chr3:172259239-172259319 64 6.05e-05 gcggatcacc tgaggtca cgaattcca chr6:26012519-26012599 19 6.05e-05 ggaagagaca tgaggtca ttttatgggc chr16:9221554-9221634 55 6.05e-05 CGGGGGCATC TGAGGTCA GCCTCGAGCC chr17:60258289-60258369 7 6.05e-05 gttaag tgaggtca taagggtggg chr3:177051983-177052063 48 6.05e-05 TGAGTTCAGA TGAGGTCA CTGTGGTTTG chr3:14416863-14416943 39 6.05e-05 TAGGGTGAAA TGAGGTCA TGGACGGATT chr11:47961353-47961433 13 6.05e-05 acagatcatt tgaggtca ggagttcgag chr2:170408187-170408267 38 6.05e-05 gagggtcact tgaggtca cttgaggttg chr3:195581248-195581328 35 6.05e-05 gtgggtcact tgaggtca ggagtttaag chr8:56765328-56765408 21 6.05e-05 gtaggtcacc tgaggtca ggagtttgag chr16:21275686-21275766 6 6.05e-05 TTGTG TGAGGTCA CTCAGGCGGA chrX:65709282-65709362 54 6.05e-05 agcagcagtc tgaggtca acctgggaca chr4:6809524-6809604 60 6.05e-05 gtggatcact tgaggtca ggagaccagc chr1:227581236-227581316 9 6.05e-05 agttcaga tgaggtca tagtggagta chr12:25428870-25428950 26 6.05e-05 tgaggtcacc tgaggtca ggagttcgag chr1:246536048-246536128 28 6.05e-05 gcgggtcacc tgaggtca ggagagagga chr3:195951289-195951369 60 6.05e-05 gcgggtcagt tgaggtca gttcaagacc chr6:107443358-107443438 71 6.05e-05 tgaggttatt tgaggtca ag chr4:140135399-140135479 13 9.17e-05 ctgcttggcg tgtcctca tatggccttg chr16:20927201-20927281 63 9.17e-05 AGTGGCTCAG TGTCCTCA GAAGACCCTA chr6:41978189-41978269 13 9.17e-05 AGAGGAAGAA TGTCCTCA TTTCACCCAG chr2:216164340-216164420 19 9.17e-05 cttcctgctg tgtcctca cataaccttt chr2:74304837-74304917 54 9.17e-05 GTGGTGGCAG TGTCCTCA GCTCACCCTC chr2:114665019-114665099 38 9.17e-05 gttcacctct tgtcctca agtgaccttc chr10:62535555-62535635 43 9.17e-05 cccaccctca tgtcctca tctaaaccta chr13:22583716-22583796 26 9.17e-05 ttccgggtga tgtcctca gatgaccttt chr12:29408165-29408245 20 9.17e-05 attctccctg tgtcctca catagccttt chr2:24846603-24846683 17 9.17e-05 catcttcctg tgtcctca cattaccttt chr17:18075988-18076068 26 9.17e-05 gtcctcactg tgtcctca catggccttt chr6:14454314-14454394 27 9.17e-05 cttctggctg tgtcctca catggccttt chr15:49271002-49271082 31 9.17e-05 cttctggctg tgtcctca catgaccttt chr20:19983387-19983467 23 9.17e-05 AGCCCCACCC TGTCCTCA CGTAACCTCT chr9:36573687-36573767 44 9.17e-05 ctccagctcg tgtcctca ggtgatccgc chr20:32418321-32418401 29 9.17e-05 cttcttgctg tgtcctca catggccttt chr8:117557410-117557490 28 9.17e-05 cttctagctg tgtcctca tttggccttt chrX:2451529-2451609 9 9.17e-05 tgttgctg tgtcctca cgtagcctta chr5:135524770-135524850 11 9.17e-05 cttctcaccg tgtcctca catggccttt chr6:144851391-144851471 24 9.17e-05 cttcttgctg tgtcctca catgagagag chr12:117507404-11750748 47 9.17e-05 CTCCCCTAGA TGTCCTCA GATGACTTCT chr1:14136400-14136480 58 9.17e-05 cttctgtctg tgtcctca catgaccttt chr15:68190143-68190223 24 9.17e-05 cttcttgctg tgtcctca agtgaccttt chr22:38077793-38077873 7 9.17e-05 CTGCCT TGTCCTCA GTTCACCCAC chr22:50327878-50327958 53 9.17e-05 GCCTCAGCCA TGTCCTCA GCTGACCTGG chr6:167177693-167177773 31 1.23e-04 CCCGGCACAG TGTGGTCA GGGTCATTTA chr3:6686419-6686499 26 1.52e-04 tttctctcca tgagcaca ccctagaaag chr3:170530961-170531041 21 1.82e-04 aagggttatg tgaggaca caggaataaa chr7:2996266-2996346 11 1.82e-04 gaaggtcccc tgaggaca ttggtgacac chr16:74876454-74876534 29 1.82e-04 TGGGGGCATG TGAGGACA CAGCCCTGCA chr21:46256574-46256654 60 1.82e-04 taagagcaga tgaggaca cagaccacgt chr1:28116138-28116218 47 1.82e-04 GAGGGCCATT TGAGGACA CAGTGTCCTT chr3:169850325-169850405 63 1.82e-04 caaggccatg tgaggaca tctgcaagcc chr6:126245541-126245621 9 1.82e-04 gtgtcatt tgaggaca accagacact chr2:178544693-178544773 31 1.82e-04 GAAGGTGACA TGAGGACA GCTACAGAGG chr4:169937255-169937335 37 1.82e-04 caaggccatg tgaggaca cagtgagaag chr11:18032884-18032964 52 1.82e-04 aaaggccatg tgaggaca cagtgaaaaa chr6:15491811-15491891 34 1.82e-04 GAGGTTGAAC TGAGGACA GCGTCATAAT chr10:65181538-65181618 37 1.82e-04 gaaggccatg tgaggaca tggcaagaaa chr5:56738385-56738465 56 1.82e-04 aagtgtcatt tgaggaca cctaaaggtg chr16:47181139-47181219 68 1.82e-04 aaaggccatg tgaggaca cagca chr15:40430148-40430228 36 1.82e-04 aaaggccaca tgaggaca cggtcagaag chr8:105542641-105542721 50 1.82e-04 aaaggccatg tgaggaca caatgagaag chr10:102823664-10282374 25 1.82e-04 GAGGGTGAAA TGAGGACA GGGGAGCAGT chr14:102094864-10209494 39 1.82e-04 CGGGGTGACC TGAGGACA CCCGAAGACA chr11:76572841-76572921 40 1.82e-04 AGGGGTCATC TGAGGACA CTACTTCCAC chr5:6544097-6544177 55 1.82e-04 CAAGGTCACA TGAGGACA CAGGCCATCT chr4:174968777-174968857 13 1.82e-04 aaagatcatg tgaggaca cagggagaag chr4:139867604-139867684 71 1.82e-04 aaaggccaca tgaggaca ca chr11:46231747-46231827 52 2.15e-04 AAGAGGACAC TGGCCTCA ATGGTGAGTC chr12:118726183-11872626 55 2.15e-04 aatgcccata tgggctca cagtgggaag chr13:60832661-60832741 27 2.49e-04 cacagcagtc tggggtca acctgggacg chr7:140375287-140375367 38 2.49e-04 ATGTGTCATC TGGGGTCA GTGTGGATTG chr4:6705718-6705798 1 2.49e-04 . tggggtca aacaaggtga chr17:38668524-38668604 47 2.49e-04 AGGAATGCAA TGGGGTCA CCTGGGGACA chr9:93949239-93949319 20 2.49e-04 gtgttccctg tggggtca gctaaggcca chr20:33126639-33126719 32 2.49e-04 gttcagagta tggggtca aacccaggtc chr17:62832862-62832942 22 2.49e-04 TGGGGTAAAA TGGGGTCA CGAGTGAAGC chr1:206592852-206592932 59 3.10e-04 TTTGCCTTAC TGACCCCA TCTGATCTCA chr3:72067678-72067758 47 3.10e-04 tggccctagc tgacccca ccggccctag chr5:96382082-96382162 47 3.10e-04 tgtccttatt tgacctta cttgagctta chr19:35879744-35879824 18 3.10e-04 ggcaaccaac tgacccca cctgaaccca chr5:34673740-34673820 37 3.10e-04 ttgccttatg tgacCCCA CATCCTGTGC chr2:205299509-205299589 58 3.10e-04 ACTGCAGGGG TGACCCCA GGACAGCTTT chr6:34663363-34663443 56 3.10e-04 AGCATTCTGG TGACCCCA GATGAACCCT chr22:50701532-50701612 53 3.10e-04 AGACACTGCC TGACCCCA AATGGCCTGG chr6:47215031-47215111 23 3.10e-04 TTAAGTAACT TGACCTTA AATAACCCTC chr6:90049500-90049580 11 4.00e-04 gaaggtcact tgaggcca ggagtttgag chr1:40121420-40121500 56 4.00e-04 aaaggtcagc tgaggcca cgaggagaca chr6:43464519-43464599 25 4.00e-04 GAAGGCCACC TGAGGTTA CTGCCTGATC chr2:114361131-114361211 37 4.31e-04 cgcccgggtc tgacctga gaagaactct chr3:71419511-71419591 54 5.19e-04 CGAGGTCACC TGAGTTCA CACACCATAG chr1:23977848-23977928 3 5.19e-04 AG TGAGTTCA TCTGATCTCC chr1:52830937-52831017 71 5.19e-04 atgggtgccc tgaggtga cc chr17:71027894-71027974 66 5.19e-04 CAATTTCACA TGAGTTCA GTCTTTC chr11:63712601-63712681 65 5.19e-04 ATCTGTGTCC TGAGGTGA ACCCTTTG chr22:41959216-41959296 8 5.49e-04 AATCAGG TCACCTCA GGCTGCAAGA chr12:23208130-23208210 57 5.49e-04 GAAAAAGATA TCACCTCA TGTGACCCTA chr19:10426988-10427068 59 5.49e-04 AGGCCCAGGG TCACCTCA GGTCGACAGG chr7:66691561-66691641 8 7.16e-04 accaagt tgtcctta aaaactctgc chr11:119312115-11931219 25 7.16e-04 cttcgccctg tgtcctta tgcagccttt chr16:46782320-46782400 53 7.16e-04 GGGGCCCCTT TGACATCA CGGCAGCATT chr19:45417108-45417188 49 7.16e-04 GAGGGGGGGA TGAGATCA CAGGGTTATT chr7:135629646-135629726 34 7.16e-04 catcatagag tgtcctta cataaaccta chr1:90288700-90288780 41 7.16e-04 GAGAGGAAAC TGTCCTTA GATGACCCAG chr10:1851459-1851539 17 7.16e-04 CGCATGCGCG TGTCCCCA TGTTCCCCCA chr19:45429675-45429755 38 7.16e-04 GAGGGGGGGA TGAGATCA CAGGGTTATT chr2:114649712-114649792 60 7.16e-04 TGAGATAAAC TGTCCTTA AGTGACCTCC chr6:11093490-11093570 8 7.16e-04 GTGCAGC TGTCCTTA AGTCACCCGC chr17:1696846-1696926 12 7.16e-04 aaaagtcaca tcaggtca cttctgtcta chr11:62728619-62728699 33 7.16e-04 gtgtgactgg tgtcctta caagaggaga chr12:56661358-56661438 26 7.16e-04 CCCCCAGCCC TGTCCTTA GCTGCCCTCG chr8:41670720-41670800 59 7.16e-04 aaagttcaca tcaggtca tctggcttca chr6:26155980-26156060 59 7.16e-04 ACCAGTTTGA TGAACTCA AATGCCCTCG chr5:146345813-146345893 37 7.16e-04 GGAGGTTATG TCAGGTCA CCTGGTCACA chr1:25543630-25543710 24 7.16e-04 ataggactga tgtcctta taagaggagg chr6:10315025-10315105 21 8.24e-04 AGGGGACATT TGGGGACA CTGTTGTCAA chr2:225350110-225350190 10 8.24e-04 acagcagtc tgaagtca acctgggaca chr11:5249089-5249169 30 8.24e-04 GGAGGTTAAC TGGGGACA TCTAACTGTT chr19:8439160-8439240 20 8.24e-04 GTAGGTCCCC TGGGGACA CAAGCAGGCG chr10:99503356-99503436 11 8.24e-04 AAGGGTCATC TGGGGACA TGGCATGAGT chr6:16241744-16241824 54 8.24e-04 CAGGGTCATG TGGGGACA TTTGGATAAT chr1:235053437-235053517 41 8.83e-04 tgacctcgct taacctca gccacctccg chr10:43119610-43119690 3 8.83e-04 ac taacctca tcgtgagggc chr17:55131468-55131548 43 8.83e-04 TGCATATAAC TGTCCTGA ATTCACCTTC chr3:37684900-37684980 40 8.83e-04 GGTTAGACCA TGTCCTGA AGTGACCTGT chr2:178151091-178151171 29 8.83e-04 tgagcttttg tgtcctga aatgaccttt chr5:118656359-118656439 68 8.83e-04 tttgaagcac tgtcctga cttga chr5:86405756-86405836 63 8.83e-04 accacccttg taacctca tttaacctta chr3:58950000-58950080 22 8.83e-04 aatgccttca tgtcctga aaagaccttt chr6:35778949-35779029 2 8.83e-04 t taacctca agagagcgga chr16:28608342-28608422 62 8.83e-04 GGGTGTTGTC TGTGCTGA GGGTTTCTTA chr19:2168289-2168369 73 8.83e-04 gcagagatac tgtgctga chr16:49654594-49654674 40 1.35e-03 GTCACTCCCT TGGGGCCA ACCTGGGTCA chr1:211546006-211546086 69 1.35e-03 GAGGACTTCT TGGGGCCA GAAC chr11:34621306-34621386 66 1.35e-03 AGAGTTCATC TGGGGTTA GTTTCTA chr2:132419615-132419695 60 1.38e-03 ATGGGCCACC TGGGCTGA TAGCAGTTTC chr19:3986358-3986438 25 1.46e-03 TGTCCTAATC TGACCCTA AGAAACAGTT chr7:55640628-55640708 66 1.46e-03 TCTCCTGCTC TGACCCTA CTTGAAC chr20:39636874-39636954 70 1.55e-03 aactctgcca tggcttca cag chr3:171679313-171679393 17 1.55e-03 atctggattc tgggttca gtgttgacct chr1:184715064-184715144 23 1.68e-03 CAAACTAAAC TGAACACA AATACTCAAA chr5:130943429-130943509 70 1.68e-03 tgggggcacg tcaggaca cct -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGASSTCA MEME-1 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr22:22391808-22391888 3e-05 63_[+1]_9 chr6:15033556-15033636 3e-05 26_[+1]_46 chr2:74198310-74198390 3e-05 16_[+1]_56 chr19:14618750-14618830 3e-05 21_[+1]_51 chr1:225633225-225633305 3e-05 49_[+1]_23 chr16:75612354-75612434 3e-05 40_[+1]_32 chr6:14691379-14691459 3e-05 62_[+1]_10 chr12:49657293-49657373 3e-05 44_[+1]_28 chr11:46736121-46736201 3e-05 16_[+1]_56 chr11:68103313-68103393 3e-05 17_[+1]_55 chr11:75186750-75186830 3e-05 8_[+1]_64 chr2:9835792-9835872 3e-05 52_[+1]_20 chr9:86602174-86602254 3e-05 20_[+1]_52 chr5:180588657-180588737 3e-05 56_[+1]_16 chr19:8488109-8488189 3e-05 61_[+1]_11 chr12:67949353-67949433 3e-05 10_[+1]_62 chrX:154365885-154365965 3e-05 21_[+1]_51 chr1:183462912-183462992 3e-05 29_[+1]_43 chr20:23095847-23095927 3e-05 24_[+1]_48 chr3:112532046-112532126 3e-05 55_[+1]_17 chr19:34753366-34753446 3e-05 61_[+1]_11 chr1:25605005-25605085 3e-05 38_[+1]_34 chr18:8610444-8610524 3e-05 72_[+1] chr4:185668249-185668329 3e-05 33_[+1]_39 chr17:57862775-57862855 6e-05 42_[+1]_30 chr8:68989780-68989860 6e-05 5_[+1]_67 chr20:47547498-47547578 6e-05 22_[+1]_50 chr11:113568663-11356874 6e-05 41_[+1]_31 chr12:96866469-96866549 6e-05 6_[+1]_66 chr3:172259239-172259319 6e-05 63_[+1]_9 chr6:26012519-26012599 6e-05 18_[+1]_54 chr16:9221554-9221634 6e-05 54_[+1]_18 chr17:60258289-60258369 6e-05 6_[+1]_66 chr3:177051983-177052063 6e-05 47_[+1]_25 chr3:14416863-14416943 6e-05 38_[+1]_34 chr11:47961353-47961433 6e-05 12_[+1]_60 chr2:170408187-170408267 6e-05 37_[+1]_35 chr3:195581248-195581328 6e-05 34_[+1]_38 chr8:56765328-56765408 6e-05 20_[+1]_52 chr16:21275686-21275766 6e-05 5_[+1]_67 chrX:65709282-65709362 6e-05 53_[+1]_19 chr4:6809524-6809604 6e-05 59_[+1]_13 chr1:227581236-227581316 6e-05 8_[+1]_64 chr12:25428870-25428950 6e-05 25_[+1]_47 chr1:246536048-246536128 6e-05 27_[+1]_45 chr3:195951289-195951369 6e-05 59_[+1]_13 chr6:107443358-107443438 6e-05 70_[+1]_2 chr4:140135399-140135479 9.2e-05 12_[+1]_60 chr16:20927201-20927281 9.2e-05 62_[+1]_10 chr6:41978189-41978269 9.2e-05 12_[+1]_60 chr2:216164340-216164420 9.2e-05 18_[+1]_54 chr2:74304837-74304917 9.2e-05 53_[+1]_19 chr2:114665019-114665099 9.2e-05 37_[+1]_35 chr10:62535555-62535635 9.2e-05 42_[+1]_30 chr13:22583716-22583796 9.2e-05 25_[+1]_47 chr12:29408165-29408245 9.2e-05 19_[+1]_53 chr2:24846603-24846683 9.2e-05 16_[+1]_56 chr17:18075988-18076068 9.2e-05 25_[+1]_47 chr6:14454314-14454394 9.2e-05 26_[+1]_46 chr15:49271002-49271082 9.2e-05 30_[+1]_42 chr20:19983387-19983467 9.2e-05 22_[+1]_50 chr9:36573687-36573767 9.2e-05 43_[+1]_29 chr20:32418321-32418401 9.2e-05 28_[+1]_44 chr8:117557410-117557490 9.2e-05 27_[+1]_45 chrX:2451529-2451609 9.2e-05 8_[+1]_64 chr5:135524770-135524850 9.2e-05 10_[+1]_62 chr6:144851391-144851471 9.2e-05 23_[+1]_49 chr12:117507404-11750748 9.2e-05 46_[+1]_26 chr1:14136400-14136480 9.2e-05 57_[+1]_15 chr15:68190143-68190223 9.2e-05 23_[+1]_49 chr22:38077793-38077873 9.2e-05 6_[+1]_66 chr22:50327878-50327958 9.2e-05 52_[+1]_20 chr6:167177693-167177773 0.00012 30_[+1]_42 chr3:6686419-6686499 0.00015 25_[+1]_47 chr3:170530961-170531041 0.00018 20_[+1]_52 chr7:2996266-2996346 0.00018 10_[+1]_62 chr16:74876454-74876534 0.00018 28_[+1]_44 chr21:46256574-46256654 0.00018 59_[+1]_13 chr1:28116138-28116218 0.00018 46_[+1]_26 chr3:169850325-169850405 0.00018 62_[+1]_10 chr6:126245541-126245621 0.00018 8_[+1]_64 chr2:178544693-178544773 0.00018 30_[+1]_42 chr4:169937255-169937335 0.00018 36_[+1]_36 chr11:18032884-18032964 0.00018 51_[+1]_21 chr6:15491811-15491891 0.00018 33_[+1]_39 chr10:65181538-65181618 0.00018 36_[+1]_36 chr5:56738385-56738465 0.00018 55_[+1]_17 chr16:47181139-47181219 0.00018 67_[+1]_5 chr15:40430148-40430228 0.00018 35_[+1]_37 chr8:105542641-105542721 0.00018 49_[+1]_23 chr10:102823664-10282374 0.00018 24_[+1]_48 chr14:102094864-10209494 0.00018 38_[+1]_34 chr11:76572841-76572921 0.00018 39_[+1]_33 chr5:6544097-6544177 0.00018 54_[+1]_18 chr4:174968777-174968857 0.00018 12_[+1]_60 chr4:139867604-139867684 0.00018 70_[+1]_2 chr11:46231747-46231827 0.00022 51_[+1]_21 chr12:118726183-11872626 0.00022 54_[+1]_18 chr13:60832661-60832741 0.00025 26_[+1]_46 chr7:140375287-140375367 0.00025 37_[+1]_35 chr4:6705718-6705798 0.00025 [+1]_72 chr17:38668524-38668604 0.00025 46_[+1]_26 chr9:93949239-93949319 0.00025 19_[+1]_53 chr20:33126639-33126719 0.00025 31_[+1]_41 chr17:62832862-62832942 0.00025 21_[+1]_51 chr1:206592852-206592932 0.00031 58_[+1]_14 chr3:72067678-72067758 0.00031 46_[+1]_26 chr5:96382082-96382162 0.00031 46_[+1]_26 chr19:35879744-35879824 0.00031 17_[+1]_55 chr5:34673740-34673820 0.00031 36_[+1]_36 chr2:205299509-205299589 0.00031 57_[+1]_15 chr6:34663363-34663443 0.00031 55_[+1]_17 chr22:50701532-50701612 0.00031 52_[+1]_20 chr6:47215031-47215111 0.00031 22_[+1]_50 chr6:90049500-90049580 0.0004 10_[+1]_62 chr1:40121420-40121500 0.0004 55_[+1]_17 chr6:43464519-43464599 0.0004 24_[+1]_48 chr2:114361131-114361211 0.00043 36_[+1]_36 chr3:71419511-71419591 0.00052 53_[+1]_19 chr1:23977848-23977928 0.00052 2_[+1]_70 chr1:52830937-52831017 0.00052 70_[+1]_2 chr17:71027894-71027974 0.00052 65_[+1]_7 chr11:63712601-63712681 0.00052 64_[+1]_8 chr22:41959216-41959296 0.00055 7_[+1]_65 chr12:23208130-23208210 0.00055 56_[+1]_16 chr19:10426988-10427068 0.00055 58_[+1]_14 chr7:66691561-66691641 0.00072 7_[+1]_65 chr11:119312115-11931219 0.00072 24_[+1]_48 chr16:46782320-46782400 0.00072 52_[+1]_20 chr19:45417108-45417188 0.00072 48_[+1]_24 chr7:135629646-135629726 0.00072 33_[+1]_39 chr1:90288700-90288780 0.00072 40_[+1]_32 chr10:1851459-1851539 0.00072 16_[+1]_56 chr19:45429675-45429755 0.00072 37_[+1]_35 chr2:114649712-114649792 0.00072 59_[+1]_13 chr6:11093490-11093570 0.00072 7_[+1]_65 chr17:1696846-1696926 0.00072 11_[+1]_61 chr11:62728619-62728699 0.00072 32_[+1]_40 chr12:56661358-56661438 0.00072 25_[+1]_47 chr8:41670720-41670800 0.00072 58_[+1]_14 chr6:26155980-26156060 0.00072 58_[+1]_14 chr5:146345813-146345893 0.00072 36_[+1]_36 chr1:25543630-25543710 0.00072 23_[+1]_49 chr6:10315025-10315105 0.00082 20_[+1]_52 chr2:225350110-225350190 0.00082 9_[+1]_63 chr11:5249089-5249169 0.00082 29_[+1]_43 chr19:8439160-8439240 0.00082 19_[+1]_53 chr10:99503356-99503436 0.00082 10_[+1]_62 chr6:16241744-16241824 0.00082 53_[+1]_19 chr1:235053437-235053517 0.00088 40_[+1]_32 chr10:43119610-43119690 0.00088 2_[+1]_70 chr17:55131468-55131548 0.00088 42_[+1]_30 chr3:37684900-37684980 0.00088 39_[+1]_33 chr2:178151091-178151171 0.00088 28_[+1]_44 chr5:118656359-118656439 0.00088 67_[+1]_5 chr5:86405756-86405836 0.00088 62_[+1]_10 chr3:58950000-58950080 0.00088 21_[+1]_51 chr6:35778949-35779029 0.00088 1_[+1]_71 chr16:28608342-28608422 0.00088 61_[+1]_11 chr19:2168289-2168369 0.00088 72_[+1] chr16:49654594-49654674 0.0013 39_[+1]_33 chr1:211546006-211546086 0.0013 68_[+1]_4 chr11:34621306-34621386 0.0013 65_[+1]_7 chr2:132419615-132419695 0.0014 59_[+1]_13 chr19:3986358-3986438 0.0015 24_[+1]_48 chr7:55640628-55640708 0.0015 65_[+1]_7 chr20:39636874-39636954 0.0015 69_[+1]_3 chr3:171679313-171679393 0.0015 16_[+1]_56 chr1:184715064-184715144 0.0017 22_[+1]_50 chr5:130943429-130943509 0.0017 69_[+1]_3 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGASSTCA MEME-1 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF TGASSTCA width=8 seqs=170 chr22:22391808-22391888 ( 64) TGACCTCA 1 chr6:15033556-15033636 ( 27) TGACCTCA 1 chr2:74198310-74198390 ( 17) TGACCTCA 1 chr19:14618750-14618830 ( 22) TGACCTCA 1 chr1:225633225-225633305 ( 50) TGACCTCA 1 chr16:75612354-75612434 ( 41) TGACCTCA 1 chr6:14691379-14691459 ( 63) TGACCTCA 1 chr12:49657293-49657373 ( 45) TGACCTCA 1 chr11:46736121-46736201 ( 17) TGACCTCA 1 chr11:68103313-68103393 ( 18) TGACCTCA 1 chr11:75186750-75186830 ( 9) TGAGCTCA 1 chr2:9835792-9835872 ( 53) TGACCTCA 1 chr9:86602174-86602254 ( 21) TGACCTCA 1 chr5:180588657-180588737 ( 57) TGACCTCA 1 chr19:8488109-8488189 ( 62) TGACCTCA 1 chr12:67949353-67949433 ( 11) TGACCTCA 1 chrX:154365885-154365965 ( 22) TGACCTCA 1 chr1:183462912-183462992 ( 30) TGACCTCA 1 chr20:23095847-23095927 ( 25) TGACCTCA 1 chr3:112532046-112532126 ( 56) TGACCTCA 1 chr19:34753366-34753446 ( 62) TGACCTCA 1 chr1:25605005-25605085 ( 39) TGACCTCA 1 chr18:8610444-8610524 ( 73) TGACCTCA 1 chr4:185668249-185668329 ( 34) TGACCTCA 1 chr17:57862775-57862855 ( 43) TGAGGTCA 1 chr8:68989780-68989860 ( 6) TGAGGTCA 1 chr20:47547498-47547578 ( 23) TGAGGTCA 1 chr11:113568663-11356874 ( 42) TGAGGTCA 1 chr12:96866469-96866549 ( 7) TGAGGTCA 1 chr3:172259239-172259319 ( 64) TGAGGTCA 1 chr6:26012519-26012599 ( 19) TGAGGTCA 1 chr16:9221554-9221634 ( 55) TGAGGTCA 1 chr17:60258289-60258369 ( 7) TGAGGTCA 1 chr3:177051983-177052063 ( 48) TGAGGTCA 1 chr3:14416863-14416943 ( 39) TGAGGTCA 1 chr11:47961353-47961433 ( 13) TGAGGTCA 1 chr2:170408187-170408267 ( 38) TGAGGTCA 1 chr3:195581248-195581328 ( 35) TGAGGTCA 1 chr8:56765328-56765408 ( 21) TGAGGTCA 1 chr16:21275686-21275766 ( 6) TGAGGTCA 1 chrX:65709282-65709362 ( 54) TGAGGTCA 1 chr4:6809524-6809604 ( 60) TGAGGTCA 1 chr1:227581236-227581316 ( 9) TGAGGTCA 1 chr12:25428870-25428950 ( 26) TGAGGTCA 1 chr1:246536048-246536128 ( 28) TGAGGTCA 1 chr3:195951289-195951369 ( 60) TGAGGTCA 1 chr6:107443358-107443438 ( 71) TGAGGTCA 1 chr4:140135399-140135479 ( 13) TGTCCTCA 1 chr16:20927201-20927281 ( 63) TGTCCTCA 1 chr6:41978189-41978269 ( 13) TGTCCTCA 1 chr2:216164340-216164420 ( 19) TGTCCTCA 1 chr2:74304837-74304917 ( 54) TGTCCTCA 1 chr2:114665019-114665099 ( 38) TGTCCTCA 1 chr10:62535555-62535635 ( 43) TGTCCTCA 1 chr13:22583716-22583796 ( 26) TGTCCTCA 1 chr12:29408165-29408245 ( 20) TGTCCTCA 1 chr2:24846603-24846683 ( 17) TGTCCTCA 1 chr17:18075988-18076068 ( 26) TGTCCTCA 1 chr6:14454314-14454394 ( 27) TGTCCTCA 1 chr15:49271002-49271082 ( 31) TGTCCTCA 1 chr20:19983387-19983467 ( 23) TGTCCTCA 1 chr9:36573687-36573767 ( 44) TGTCCTCA 1 chr20:32418321-32418401 ( 29) TGTCCTCA 1 chr8:117557410-117557490 ( 28) TGTCCTCA 1 chrX:2451529-2451609 ( 9) TGTCCTCA 1 chr5:135524770-135524850 ( 11) TGTCCTCA 1 chr6:144851391-144851471 ( 24) TGTCCTCA 1 chr12:117507404-11750748 ( 47) TGTCCTCA 1 chr1:14136400-14136480 ( 58) TGTCCTCA 1 chr15:68190143-68190223 ( 24) TGTCCTCA 1 chr22:38077793-38077873 ( 7) TGTCCTCA 1 chr22:50327878-50327958 ( 53) TGTCCTCA 1 chr6:167177693-167177773 ( 31) TGTGGTCA 1 chr3:6686419-6686499 ( 26) TGAGCACA 1 chr3:170530961-170531041 ( 21) TGAGGACA 1 chr7:2996266-2996346 ( 11) TGAGGACA 1 chr16:74876454-74876534 ( 29) TGAGGACA 1 chr21:46256574-46256654 ( 60) TGAGGACA 1 chr1:28116138-28116218 ( 47) TGAGGACA 1 chr3:169850325-169850405 ( 63) TGAGGACA 1 chr6:126245541-126245621 ( 9) TGAGGACA 1 chr2:178544693-178544773 ( 31) TGAGGACA 1 chr4:169937255-169937335 ( 37) TGAGGACA 1 chr11:18032884-18032964 ( 52) TGAGGACA 1 chr6:15491811-15491891 ( 34) TGAGGACA 1 chr10:65181538-65181618 ( 37) TGAGGACA 1 chr5:56738385-56738465 ( 56) TGAGGACA 1 chr16:47181139-47181219 ( 68) TGAGGACA 1 chr15:40430148-40430228 ( 36) TGAGGACA 1 chr8:105542641-105542721 ( 50) TGAGGACA 1 chr10:102823664-10282374 ( 25) TGAGGACA 1 chr14:102094864-10209494 ( 39) TGAGGACA 1 chr11:76572841-76572921 ( 40) TGAGGACA 1 chr5:6544097-6544177 ( 55) TGAGGACA 1 chr4:174968777-174968857 ( 13) TGAGGACA 1 chr4:139867604-139867684 ( 71) TGAGGACA 1 chr11:46231747-46231827 ( 52) TGGCCTCA 1 chr12:118726183-11872626 ( 55) TGGGCTCA 1 chr13:60832661-60832741 ( 27) TGGGGTCA 1 chr7:140375287-140375367 ( 38) TGGGGTCA 1 chr4:6705718-6705798 ( 1) TGGGGTCA 1 chr17:38668524-38668604 ( 47) TGGGGTCA 1 chr9:93949239-93949319 ( 20) TGGGGTCA 1 chr20:33126639-33126719 ( 32) TGGGGTCA 1 chr17:62832862-62832942 ( 22) TGGGGTCA 1 chr1:206592852-206592932 ( 59) TGACCCCA 1 chr3:72067678-72067758 ( 47) TGACCCCA 1 chr5:96382082-96382162 ( 47) TGACCTTA 1 chr19:35879744-35879824 ( 18) TGACCCCA 1 chr5:34673740-34673820 ( 37) TGACCCCA 1 chr2:205299509-205299589 ( 58) TGACCCCA 1 chr6:34663363-34663443 ( 56) TGACCCCA 1 chr22:50701532-50701612 ( 53) TGACCCCA 1 chr6:47215031-47215111 ( 23) TGACCTTA 1 chr6:90049500-90049580 ( 11) TGAGGCCA 1 chr1:40121420-40121500 ( 56) TGAGGCCA 1 chr6:43464519-43464599 ( 25) TGAGGTTA 1 chr2:114361131-114361211 ( 37) TGACCTGA 1 chr3:71419511-71419591 ( 54) TGAGTTCA 1 chr1:23977848-23977928 ( 3) TGAGTTCA 1 chr1:52830937-52831017 ( 71) TGAGGTGA 1 chr17:71027894-71027974 ( 66) TGAGTTCA 1 chr11:63712601-63712681 ( 65) TGAGGTGA 1 chr22:41959216-41959296 ( 8) TCACCTCA 1 chr12:23208130-23208210 ( 57) TCACCTCA 1 chr19:10426988-10427068 ( 59) TCACCTCA 1 chr7:66691561-66691641 ( 8) TGTCCTTA 1 chr11:119312115-11931219 ( 25) TGTCCTTA 1 chr16:46782320-46782400 ( 53) TGACATCA 1 chr19:45417108-45417188 ( 49) TGAGATCA 1 chr7:135629646-135629726 ( 34) TGTCCTTA 1 chr1:90288700-90288780 ( 41) TGTCCTTA 1 chr10:1851459-1851539 ( 17) TGTCCCCA 1 chr19:45429675-45429755 ( 38) TGAGATCA 1 chr2:114649712-114649792 ( 60) TGTCCTTA 1 chr6:11093490-11093570 ( 8) TGTCCTTA 1 chr17:1696846-1696926 ( 12) TCAGGTCA 1 chr11:62728619-62728699 ( 33) TGTCCTTA 1 chr12:56661358-56661438 ( 26) TGTCCTTA 1 chr8:41670720-41670800 ( 59) TCAGGTCA 1 chr6:26155980-26156060 ( 59) TGAACTCA 1 chr5:146345813-146345893 ( 37) TCAGGTCA 1 chr1:25543630-25543710 ( 24) TGTCCTTA 1 chr6:10315025-10315105 ( 21) TGGGGACA 1 chr2:225350110-225350190 ( 10) TGAAGTCA 1 chr11:5249089-5249169 ( 30) TGGGGACA 1 chr19:8439160-8439240 ( 20) TGGGGACA 1 chr10:99503356-99503436 ( 11) TGGGGACA 1 chr6:16241744-16241824 ( 54) TGGGGACA 1 chr1:235053437-235053517 ( 41) TAACCTCA 1 chr10:43119610-43119690 ( 3) TAACCTCA 1 chr17:55131468-55131548 ( 43) TGTCCTGA 1 chr3:37684900-37684980 ( 40) TGTCCTGA 1 chr2:178151091-178151171 ( 29) TGTCCTGA 1 chr5:118656359-118656439 ( 68) TGTCCTGA 1 chr5:86405756-86405836 ( 63) TAACCTCA 1 chr3:58950000-58950080 ( 22) TGTCCTGA 1 chr6:35778949-35779029 ( 2) TAACCTCA 1 chr16:28608342-28608422 ( 62) TGTGCTGA 1 chr19:2168289-2168369 ( 73) TGTGCTGA 1 chr16:49654594-49654674 ( 40) TGGGGCCA 1 chr1:211546006-211546086 ( 69) TGGGGCCA 1 chr11:34621306-34621386 ( 66) TGGGGTTA 1 chr2:132419615-132419695 ( 60) TGGGCTGA 1 chr19:3986358-3986438 ( 25) TGACCCTA 1 chr7:55640628-55640708 ( 66) TGACCCTA 1 chr20:39636874-39636954 ( 70) TGGCTTCA 1 chr3:171679313-171679393 ( 17) TGGGTTCA 1 chr1:184715064-184715144 ( 23) TGAACACA 1 chr5:130943429-130943509 ( 70) TCAGGACA 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGASSTCA MEME-1 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 7.73608 E= 9.2e-110 -1405 -1405 -1405 205 -332 -267 184 -1405 142 -1405 -115 7 -374 93 89 -1405 -374 103 68 -304 -42 -167 -1405 162 -1405 169 -201 -145 209 -1405 -1405 -1405 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGASSTCA MEME-1 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 170 E= 9.2e-110 0.000000 0.000000 0.000000 1.000000 0.023529 0.041176 0.935294 0.000000 0.629412 0.000000 0.117647 0.252941 0.017647 0.500000 0.482353 0.000000 0.017647 0.535294 0.417647 0.029412 0.176471 0.082353 0.000000 0.741176 0.000000 0.847059 0.064706 0.088235 1.000000 0.000000 0.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGASSTCA MEME-1 regular expression -------------------------------------------------------------------------------- TG[AT][CG][CG]TCA -------------------------------------------------------------------------------- Time 4.99 secs. ******************************************************************************** ******************************************************************************** MOTIF CCAGSCTG MEME-2 width = 8 sites = 33 llr = 294 E-value = 4.6e-009 ******************************************************************************** -------------------------------------------------------------------------------- Motif CCAGSCTG MEME-2 Description -------------------------------------------------------------------------------- Simplified A 1:a:::2: pos.-specific C 7a::5a:: probability G :::a5::a matrix T 2:::::8: bits 2.1 * 1.9 *** * * 1.7 *** * * 1.5 *** * * Relative 1.3 *** *** Entropy 1.0 *** *** (12.8 bits) 0.8 ******** 0.6 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel CCAGGCTG consensus T C A sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCAGSCTG MEME-2 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr1:225633225-225633305 30 1.82e-05 accatgttgg ccaggctg gtctgaaact chr6:14691379-14691459 43 1.82e-05 gccatgttca ccaggctg gtcttgaact chr2:114665019-114665099 18 1.82e-05 gatttgttgc ccaggctg gtgttcacct chr2:9835792-9835872 33 1.82e-05 accatgttgg ccaggctg gtctcaaact chr9:36573687-36573767 24 1.82e-05 accacgttgg ccaggctg gtctccagct chr1:183462912-183462992 10 1.82e-05 cgctgttgg ccaggctg ttctcgaatg chr20:23095847-23095927 5 1.82e-05 ttgg ccaggctg gttgtgaact chr17:57862775-57862855 62 3.64e-05 gggctaaaga ccagcctg accaacatgg chr12:96866469-96866549 26 3.64e-05 gagttcggga ccagcctg gccaacatga chr6:90049500-90049580 30 3.64e-05 gagtttgaga ccagcctg ggcaacaaag chr11:47961353-47961433 32 3.64e-05 gagttcgaga ccagcctg gccaacatgg chr8:56765328-56765408 40 3.64e-05 gagtttgaga ccagcctg gccaacatgg chr4:6809524-6809604 73 3.64e-05 ggtcaggaga ccagcctg chr5:81069545-81069625 10 3.64e-05 atagtgaaa ccagcctg agtctaggaa chrX:2451529-2451609 31 3.64e-05 gccttagagc ccagcctg ttccctccag chr12:25428870-25428950 45 3.64e-05 gagttcgagt ccagcctg accaacatgg chr6:17966222-17966302 5 3.64e-05 gaga ccagcctg gccaatatgg chr1:28276703-28276783 36 7.09e-05 CCAACCCAAG TCAGGCTG CTTGGTTTCC chr17:71027894-71027974 11 7.09e-05 AGAAGGCTTT CCAGGCAG GACCTCAGTT chr16:21275686-21275766 34 7.09e-05 TGGAGGTGGG CCAGGCAG TAAAGAGAGA chr2:10148707-10148787 9 7.09e-05 gggagctc ccaggcag gtcaaatgag chr19:8488109-8488189 48 7.09e-05 accatgttag tcaggctg gtctcctgac chrX:154365885-154365965 1 7.09e-05 . tcaggctg ctctcggaac chr8:117557410-117557490 45 7.09e-05 atttggcctt tcaggctg agtgcgtggg chr22:17518847-17518927 69 7.09e-05 acgatatttg tcaggctg gtct chr20:23161397-23161477 4 7.09e-05 ACT CCAGGCAG CTGATGGGAC chrX:118603425-118603505 59 1.05e-04 TTGGGAGGGT CCAGCCAG TATGATATAC chr16:20927201-20927281 43 1.05e-04 AGGTCTCAAG CCAGCCAG TAAGTGGCTC chr18:616504-616584 45 1.38e-04 AATTGTGTAC ACAGCCTG CCCTCTAGTG chr15:52970893-52970973 53 1.38e-04 GGAGGTGTTT ACAGCCTG TGCTCGCCCC chr3:195581248-195581328 54 1.38e-04 gagtttaaga acagcctg gccaacatgg chr4:185668249-185668329 56 1.54e-04 CCCTTACTGC TCAGGCAG GAATGGACTC chrX:39992201-39992281 70 1.71e-04 aacccactgC TCAGCCAG GTT -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCAGSCTG MEME-2 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr1:225633225-225633305 1.8e-05 29_[+2]_43 chr6:14691379-14691459 1.8e-05 42_[+2]_30 chr2:114665019-114665099 1.8e-05 17_[+2]_55 chr2:9835792-9835872 1.8e-05 32_[+2]_40 chr9:36573687-36573767 1.8e-05 23_[+2]_49 chr1:183462912-183462992 1.8e-05 9_[+2]_63 chr20:23095847-23095927 1.8e-05 4_[+2]_68 chr17:57862775-57862855 3.6e-05 61_[+2]_11 chr12:96866469-96866549 3.6e-05 25_[+2]_47 chr6:90049500-90049580 3.6e-05 29_[+2]_43 chr11:47961353-47961433 3.6e-05 31_[+2]_41 chr8:56765328-56765408 3.6e-05 39_[+2]_33 chr4:6809524-6809604 3.6e-05 72_[+2] chr5:81069545-81069625 3.6e-05 9_[+2]_63 chrX:2451529-2451609 3.6e-05 30_[+2]_42 chr12:25428870-25428950 3.6e-05 44_[+2]_28 chr6:17966222-17966302 3.6e-05 4_[+2]_68 chr1:28276703-28276783 7.1e-05 35_[+2]_37 chr17:71027894-71027974 7.1e-05 10_[+2]_62 chr16:21275686-21275766 7.1e-05 33_[+2]_39 chr2:10148707-10148787 7.1e-05 8_[+2]_64 chr19:8488109-8488189 7.1e-05 47_[+2]_25 chrX:154365885-154365965 7.1e-05 [+2]_72 chr8:117557410-117557490 7.1e-05 44_[+2]_28 chr22:17518847-17518927 7.1e-05 68_[+2]_4 chr20:23161397-23161477 7.1e-05 3_[+2]_69 chrX:118603425-118603505 0.00011 58_[+2]_14 chr16:20927201-20927281 0.00011 42_[+2]_30 chr18:616504-616584 0.00014 44_[+2]_28 chr15:52970893-52970973 0.00014 52_[+2]_20 chr3:195581248-195581328 0.00014 53_[+2]_19 chr4:185668249-185668329 0.00015 55_[+2]_17 chrX:39992201-39992281 0.00017 69_[+2]_3 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCAGSCTG MEME-2 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF CCAGSCTG width=8 seqs=33 chr1:225633225-225633305 ( 30) CCAGGCTG 1 chr6:14691379-14691459 ( 43) CCAGGCTG 1 chr2:114665019-114665099 ( 18) CCAGGCTG 1 chr2:9835792-9835872 ( 33) CCAGGCTG 1 chr9:36573687-36573767 ( 24) CCAGGCTG 1 chr1:183462912-183462992 ( 10) CCAGGCTG 1 chr20:23095847-23095927 ( 5) CCAGGCTG 1 chr17:57862775-57862855 ( 62) CCAGCCTG 1 chr12:96866469-96866549 ( 26) CCAGCCTG 1 chr6:90049500-90049580 ( 30) CCAGCCTG 1 chr11:47961353-47961433 ( 32) CCAGCCTG 1 chr8:56765328-56765408 ( 40) CCAGCCTG 1 chr4:6809524-6809604 ( 73) CCAGCCTG 1 chr5:81069545-81069625 ( 10) CCAGCCTG 1 chrX:2451529-2451609 ( 31) CCAGCCTG 1 chr12:25428870-25428950 ( 45) CCAGCCTG 1 chr6:17966222-17966302 ( 5) CCAGCCTG 1 chr1:28276703-28276783 ( 36) TCAGGCTG 1 chr17:71027894-71027974 ( 11) CCAGGCAG 1 chr16:21275686-21275766 ( 34) CCAGGCAG 1 chr2:10148707-10148787 ( 9) CCAGGCAG 1 chr19:8488109-8488189 ( 48) TCAGGCTG 1 chrX:154365885-154365965 ( 1) TCAGGCTG 1 chr8:117557410-117557490 ( 45) TCAGGCTG 1 chr22:17518847-17518927 ( 69) TCAGGCTG 1 chr20:23161397-23161477 ( 4) CCAGGCAG 1 chrX:118603425-118603505 ( 59) CCAGCCAG 1 chr16:20927201-20927281 ( 43) CCAGCCAG 1 chr18:616504-616584 ( 45) ACAGCCTG 1 chr15:52970893-52970973 ( 53) ACAGCCTG 1 chr3:195581248-195581328 ( 54) ACAGCCTG 1 chr4:185668249-185668329 ( 56) TCAGGCAG 1 chrX:39992201-39992281 ( 70) TCAGCCAG 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCAGSCTG MEME-2 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 9.87609 E= 4.6e-009 -137 141 -1169 -19 -1169 193 -1169 -1169 209 -1169 -1169 -1169 -1169 -1169 194 -1169 -1169 89 98 -1169 -1169 193 -1169 -1169 4 -1169 -1169 165 -1169 -1169 194 -1169 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCAGSCTG MEME-2 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 33 E= 4.6e-009 0.090909 0.696970 0.000000 0.212121 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.484848 0.515152 0.000000 0.000000 1.000000 0.000000 0.000000 0.242424 0.000000 0.000000 0.757576 0.000000 0.000000 1.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCAGSCTG MEME-2 regular expression -------------------------------------------------------------------------------- [CT]CAG[GC]C[TA]G -------------------------------------------------------------------------------- Time 8.47 secs. ******************************************************************************** ******************************************************************************** MOTIF RTGRCCTK MEME-3 width = 8 sites = 39 llr = 333 E-value = 8.9e-010 ******************************************************************************** -------------------------------------------------------------------------------- Motif RTGRCCTK MEME-3 Description -------------------------------------------------------------------------------- Simplified A 6::6:::1 pos.-specific C ::::aa1: probability G 4:a4:::4 matrix T :a::::96 bits 2.1 * 1.9 ** ** 1.7 ** ** 1.5 ** *** Relative 1.3 ** *** Entropy 1.0 ******* (12.3 bits) 0.8 ******** 0.6 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel ATGACCTT consensus G G G sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif RTGRCCTK MEME-3 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr13:22583716-22583796 35 1.40e-05 atgtcctcag atgacctt tccttggtgc chr2:178151091-178151171 38 1.40e-05 gtgtcctgaa atgacctt ttgatgtgta chr5:118656359-118656439 23 1.40e-05 tttttgtagt atgacctt gtaaccaccc chr15:49271002-49271082 40 1.40e-05 gtgtcctcac atgacctt tcttctgagc chr6:10489424-10489504 4 1.40e-05 cac atgacctt tcctctgtga chr16:11892392-11892472 61 1.40e-05 gtgtcctcct atgacctt ttctctgtga chr1:14136400-14136480 67 1.40e-05 gtgtcctcac atgacctt tttcga chr2:74198310-74198390 26 2.91e-05 TTGACCTCAG ATGACCTG CGTGTTCCCT chr1:225633225-225633305 59 2.91e-05 ctgacctcag atgacctg cctgcctcgg chr5:81069545-81069625 65 2.91e-05 cgtgcctcaa atgacctg gggacttt chr4:7034261-7034341 44 2.91e-05 AGTGGCTTGT ATGACCTG TTCAGGGGTC chr11:46231747-46231827 2 6.03e-05 A GTGACCTT GCAGGCAAAT chr4:140135399-140135479 22 6.03e-05 gtgtcctcat atggcctt gcctctgggt chr2:114665019-114665099 47 6.03e-05 ttgtcctcaa gtgacctt cctgctttgg chr16:27482267-27482347 16 6.03e-05 TCCGTGACAA ATGGCCTT GTTGGATTTG chr17:18075988-18076068 35 6.03e-05 gtgtcctcac atggcctt tcctctgtgt chr6:14454314-14454394 36 6.03e-05 gtgtcctcac atggcctt tcttctgagt chr4:83332210-83332290 9 6.03e-05 gtcctcgt atggcctt ttctctgcgt chr20:32418321-32418401 38 6.03e-05 gtgtcctcac atggcctt tctgtggagt chr5:135524770-135524850 20 6.03e-05 gtgtcctcac atggcctt ttctccgtgc chr15:68190143-68190223 33 6.03e-05 gtgtcctcaa gtgacctt tcctttgtgt chr1:206592852-206592932 19 9.39e-05 TTACAAAGCA ATGGCCTG GGGCGGGGTT chr6:14691379-14691459 72 9.39e-05 ctgacctcag gtgacctg c chr12:49657293-49657373 54 9.39e-05 ctgacctcaa gtgacctg cctgcctcgg chr3:37684900-37684980 49 9.39e-05 ATGTCCTGAA GTGACCTG TTGAATTTGC chr3:171679313-171679393 38 9.39e-05 ttgaccttgt gtgacctg gaaaacacca chr2:46525661-46525741 49 9.39e-05 TAGGTAGTGA GTGACCTG GATTGCCCTG chr22:50701532-50701612 62 9.39e-05 CTGACCCCAA ATGGCCTG GACCCTCCCC chr12:118726183-11872626 9 1.11e-04 atgggtgg gtggcctt gtaagtagag chr1:184715064-184715144 69 1.30e-04 TAAAGTGACT GTGGCCTG GGGT chr2:178544693-178544773 61 1.30e-04 GGGGCAGGCA GTGGCCTG TGTTCAGAAG chr9:14538689-14538769 63 1.30e-04 GCAGTGATAG GTGGCCTG GAATGCCCTC chr11:86714163-86714243 30 1.43e-04 cattttacag atgaccta acagactttg chr10:43119610-43119690 30 1.43e-04 ccccaccctc atgaccta atctaaccct chr1:166668134-166668214 9 1.59e-04 GCTCATTC ATGACCCT GGATGAACTT chr20:23095847-23095927 34 1.59e-04 ctgacctcaa atgaccct ctcacctcag chr7:135629646-135629726 58 1.89e-04 cctagatggt atggccta ctacacacgt chr12:23208130-23208210 66 2.39e-04 ATCACCTCAT GTGACCCT ATGGAAC chrX:39992201-39992281 22 2.39e-04 ggcaccccag gtgaccct gaagcagtta -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif RTGRCCTK MEME-3 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr13:22583716-22583796 1.4e-05 34_[+3]_38 chr2:178151091-178151171 1.4e-05 37_[+3]_35 chr5:118656359-118656439 1.4e-05 22_[+3]_50 chr15:49271002-49271082 1.4e-05 39_[+3]_33 chr6:10489424-10489504 1.4e-05 3_[+3]_69 chr16:11892392-11892472 1.4e-05 60_[+3]_12 chr1:14136400-14136480 1.4e-05 66_[+3]_6 chr2:74198310-74198390 2.9e-05 25_[+3]_47 chr1:225633225-225633305 2.9e-05 58_[+3]_14 chr5:81069545-81069625 2.9e-05 64_[+3]_8 chr4:7034261-7034341 2.9e-05 43_[+3]_29 chr11:46231747-46231827 6e-05 1_[+3]_71 chr4:140135399-140135479 6e-05 21_[+3]_51 chr2:114665019-114665099 6e-05 46_[+3]_26 chr16:27482267-27482347 6e-05 15_[+3]_57 chr17:18075988-18076068 6e-05 34_[+3]_38 chr6:14454314-14454394 6e-05 35_[+3]_37 chr4:83332210-83332290 6e-05 8_[+3]_64 chr20:32418321-32418401 6e-05 37_[+3]_35 chr5:135524770-135524850 6e-05 19_[+3]_53 chr15:68190143-68190223 6e-05 32_[+3]_40 chr1:206592852-206592932 9.4e-05 18_[+3]_54 chr6:14691379-14691459 9.4e-05 71_[+3]_1 chr12:49657293-49657373 9.4e-05 53_[+3]_19 chr3:37684900-37684980 9.4e-05 48_[+3]_24 chr3:171679313-171679393 9.4e-05 37_[+3]_35 chr2:46525661-46525741 9.4e-05 48_[+3]_24 chr22:50701532-50701612 9.4e-05 61_[+3]_11 chr12:118726183-11872626 0.00011 8_[+3]_64 chr1:184715064-184715144 0.00013 68_[+3]_4 chr2:178544693-178544773 0.00013 60_[+3]_12 chr9:14538689-14538769 0.00013 62_[+3]_10 chr11:86714163-86714243 0.00014 29_[+3]_43 chr10:43119610-43119690 0.00014 29_[+3]_43 chr1:166668134-166668214 0.00016 8_[+3]_64 chr20:23095847-23095927 0.00016 33_[+3]_39 chr7:135629646-135629726 0.00019 57_[+3]_15 chr12:23208130-23208210 0.00024 65_[+3]_7 chrX:39992201-39992281 0.00024 21_[+3]_51 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif RTGRCCTK MEME-3 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF RTGRCCTK width=8 seqs=39 chr13:22583716-22583796 ( 35) ATGACCTT 1 chr2:178151091-178151171 ( 38) ATGACCTT 1 chr5:118656359-118656439 ( 23) ATGACCTT 1 chr15:49271002-49271082 ( 40) ATGACCTT 1 chr6:10489424-10489504 ( 4) ATGACCTT 1 chr16:11892392-11892472 ( 61) ATGACCTT 1 chr1:14136400-14136480 ( 67) ATGACCTT 1 chr2:74198310-74198390 ( 26) ATGACCTG 1 chr1:225633225-225633305 ( 59) ATGACCTG 1 chr5:81069545-81069625 ( 65) ATGACCTG 1 chr4:7034261-7034341 ( 44) ATGACCTG 1 chr11:46231747-46231827 ( 2) GTGACCTT 1 chr4:140135399-140135479 ( 22) ATGGCCTT 1 chr2:114665019-114665099 ( 47) GTGACCTT 1 chr16:27482267-27482347 ( 16) ATGGCCTT 1 chr17:18075988-18076068 ( 35) ATGGCCTT 1 chr6:14454314-14454394 ( 36) ATGGCCTT 1 chr4:83332210-83332290 ( 9) ATGGCCTT 1 chr20:32418321-32418401 ( 38) ATGGCCTT 1 chr5:135524770-135524850 ( 20) ATGGCCTT 1 chr15:68190143-68190223 ( 33) GTGACCTT 1 chr1:206592852-206592932 ( 19) ATGGCCTG 1 chr6:14691379-14691459 ( 72) GTGACCTG 1 chr12:49657293-49657373 ( 54) GTGACCTG 1 chr3:37684900-37684980 ( 49) GTGACCTG 1 chr3:171679313-171679393 ( 38) GTGACCTG 1 chr2:46525661-46525741 ( 49) GTGACCTG 1 chr22:50701532-50701612 ( 62) ATGGCCTG 1 chr12:118726183-11872626 ( 9) GTGGCCTT 1 chr1:184715064-184715144 ( 69) GTGGCCTG 1 chr2:178544693-178544773 ( 61) GTGGCCTG 1 chr9:14538689-14538769 ( 63) GTGGCCTG 1 chr11:86714163-86714243 ( 30) ATGACCTA 1 chr10:43119610-43119690 ( 30) ATGACCTA 1 chr1:166668134-166668214 ( 9) ATGACCCT 1 chr20:23095847-23095927 ( 34) ATGACCCT 1 chr7:135629646-135629726 ( 58) ATGGCCTA 1 chr12:23208130-23208210 ( 66) GTGACCCT 1 chrX:39992201-39992281 ( 22) GTGACCCT 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif RTGRCCTK MEME-3 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 9.09119 E= 8.9e-010 144 -1193 46 -1193 -1193 -1193 -1193 205 -1193 -1193 194 -1193 144 -1193 46 -1193 -1193 193 -1193 -1193 -1193 193 -1193 -1193 -1193 -135 -1193 189 -161 -1193 46 122 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif RTGRCCTK MEME-3 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 39 E= 8.9e-010 0.641026 0.000000 0.358974 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.641026 0.000000 0.358974 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.102564 0.000000 0.897436 0.076923 0.000000 0.358974 0.564103 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif RTGRCCTK MEME-3 regular expression -------------------------------------------------------------------------------- [AG]TG[AG]CCT[TG] -------------------------------------------------------------------------------- Time 11.91 secs. ******************************************************************************** ******************************************************************************** MOTIF RRGGHCAY MEME-4 width = 8 sites = 79 llr = 548 E-value = 2.6e-005 ******************************************************************************** -------------------------------------------------------------------------------- Motif RRGGHCAY MEME-4 Description -------------------------------------------------------------------------------- Simplified A 55::3:a1 pos.-specific C ::::3a:4 probability G 35aa:::2 matrix T 2:::4::3 bits 2.1 * 1.9 ** ** 1.7 ** ** 1.5 ** ** Relative 1.3 ** ** Entropy 1.0 *** ** (10.0 bits) 0.8 *** ** 0.6 **** ** 0.4 **** ** 0.2 ******** 0.0 -------- Multilevel AAGGTCAC consensus GG A T sequence C -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif RRGGHCAY MEME-4 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr11:86714163-86714243 54 1.47e-05 tttgagatga aaggtcac ataggggcaa chr18:616504-616584 20 1.47e-05 AAGGTAGCCC AAGGTCAC TGTTGCCAAT chr6:90049500-90049580 2 1.47e-05 g aaggtcac ttgaggccag chr5:6544097-6544177 46 1.47e-05 cacaGAGAGC AAGGTCAC ATGAGGACAC chr8:128876448-128876528 53 2.89e-05 Agcagggatg aaggacac ctggggaggg chr2:232046798-232046878 51 2.89e-05 TAAGCAGGCA AAGGACAC GCTGGAGCCA chr6:144851391-144851471 69 2.89e-05 cacctattat aaggacac cagt chr6:83716223-83716303 20 2.89e-05 aaggccatgc aaggacac agagagaaaa chr2:62422806-62422886 33 4.48e-05 CTGGACAGAA AAGGCCAC TGGAGTCTCG chr6:43464519-43464599 16 4.48e-05 TTCTGCCCAG AAGGCCAC CTGAGGTTAC chr9:93949239-93949319 31 4.48e-05 ggggtcagct aaggccac tgttgtgact chr15:40430148-40430228 27 4.48e-05 gcactgggga aaggccac atgaggacac chr4:139867604-139867684 62 4.48e-05 acactgagga aaggccac atgaggacac chr2:170408187-170408267 29 7.47e-05 ctgaggcagg agggtcac ttgaggtcac chr3:6686419-6686499 41 7.47e-05 acaccctaga aaggtcat gtgaggacac chr7:66691561-66691641 39 1.04e-04 ttgaatgttc agggacac cgatttgagt chr19:45417108-45417188 22 1.04e-04 GAGGTGATCT AGGGACAC GGTGTGAATG chr12:110368653-11036873 15 1.04e-04 AGGGTCAGCT AAGGACAT GAAGCCTGCA chr5:86405756-86405836 25 1.04e-04 ctcttcttat aaggacat cagttatgta chr19:45429675-45429755 11 1.04e-04 GAGGTGATCT AGGGACAC GGTGTGAATG chr3:50628467-50628547 15 1.36e-04 AGCCTCCCTT AGGGCCAC TAGGTGGGGC chr3:169850325-169850405 54 1.36e-04 ccacacactc aaggccat gtgaggacat chr4:169937255-169937335 28 1.36e-04 ctccctgtac aaggccat gtgaggacac chr11:18032884-18032964 43 1.36e-04 gcacacagaa aaggccat gtgaggacac chr10:65181538-65181618 28 1.36e-04 tacacaagag aaggccat gtgaggacat chr16:47181139-47181219 59 1.36e-04 ggcaccagga aaggccat gtgaggacac chr8:105542641-105542721 41 1.36e-04 tcatagaaaa aaggccat gtgaggacac chr3:71419511-71419591 45 1.67e-04 CATGAGAAAC GAGGTCAC CTGAGTTCAC chr7:140375287-140375367 72 1.67e-04 gaggccatgc agggtcat g chr12:25428870-25428950 17 1.67e-04 aggcgggcct gaggtcac ctgaggtcag chr10:99503356-99503436 2 1.67e-04 A AGGGTCAT CTGGGGACAT chr6:16241744-16241824 45 1.67e-04 AAAGCGCCAC AGGGTCAT GTGGGGACAT chr11:46231747-46231827 44 1.98e-04 AGGTGCAAAA GAGGACAC TGGCCTCAAT chr6:26012519-26012599 54 1.98e-04 gaggccacat gaggacac aaaaggcgac chr1:28116138-28116218 38 2.32e-04 GGGTTTTGTG AGGGCCAT TTGAGGACAC chr12:49657293-49657373 2 2.32e-04 A AGGGCCAT TTTGTATGTG chr10:6076115-6076195 23 2.80e-04 AGTGTCTGAA GAGGTCAT GCGGGGACAA chr1:40121420-40121500 47 2.80e-04 tcacagtgga aaggtcag ctgaggccac chr22:46402457-46402537 20 2.80e-04 GAAGGCCCCC GGGGTCAC TCGAGGCCAG chr4:7034261-7034341 56 2.80e-04 GACCTGTTCA GGGGTCAC ATGAGGTCTC chr6:167177693-167177773 48 3.78e-04 AGGGTCATTT AAGGCCAG CGACATTTTA chr22:38077793-38077873 71 3.78e-04 CACTAGGACT GGGGCCAC AA chr21:46256574-46256654 5 4.26e-04 aaag taggtcac taggctggtc chr20:52407724-52407804 70 4.26e-04 CTGTAGAAGC AGGGTCAG GTA chr8:56765328-56765408 12 4.26e-04 ccaaggcggg taggtcac ctgaggtcag chr11:76572841-76572921 31 4.26e-04 CTAGGAGTTA GGGGTCAT CTGAGGACAC chr6:10315025-10315105 12 4.86e-04 CATTTTGCAA GGGGACAT TTGGGGACAC chr19:14618750-14618830 56 4.86e-04 CCACAAAGCG GGGGACAT TTTTTAGTAT chr7:2996266-2996346 53 4.86e-04 tgcttcaact ggggacat gagtgtctgt chr12:5330165-5330245 61 4.86e-04 taagtcacct agggacag cccctatgcc chr10:102823664-10282374 44 4.86e-04 GGGAGCAGTT AGGGACAG AGTGGCTGCC chr14:102094864-10209494 69 4.86e-04 GGCGACTCGC GGGGACAT CCTG chr1:52830937-52831017 55 5.51e-04 ggttgcccca ggggccat gggtgccctg chr16:46782320-46782400 18 6.12e-04 GTGACAGGCC GAGGTCAG CCCAGGCCCT chr8:68989780-68989860 63 6.12e-04 GGGTTCAGGT TGGGTCAC CACAACTGCA chr2:132419615-132419695 44 6.12e-04 TGGGTCAGCT TAGGTCAT GGGCCACCTG chr7:76000322-76000402 12 6.12e-04 AGTATTACGT AAGGCCAA AGAGCACCTT chr9:127704312-127704392 27 6.12e-04 tggttcaccc gaggtcag gagttcagac chr3:195581248-195581328 26 6.12e-04 ccgaggcggg tgggtcac ttgaggtcag chr3:177315739-177315819 17 6.12e-04 CCTCCTTTAC TGGGTCAC ACTTAGGGCA chr4:40918992-40919072 62 6.72e-04 GCTCTCACTC AGGGTCAA GTCAGGGCGG chr2:225350110-225350190 21 6.72e-04 gaagtcaacc tgggacac tcaagcttgg chrX:65709282-65709362 65 6.72e-04 gaggtcaacc tgggacac tcgagctt chr1:25543630-25543710 67 6.72e-04 tgtgaaggca gaggacag gtcatg chr20:23161397-23161477 16 6.72e-04 AGGCAGCTGA TGGGACAC TGGGGCCCAG chr2:205299509-205299589 24 7.37e-04 AATTATCTAT GAGGCCAG CTCCCCTTGT chr16:49654594-49654674 51 7.87e-04 GGGGCCAACC TGGGTCAT GGCAAGTTTG chr19:51568014-51568094 67 7.87e-04 CTGGGGTCGG AGGGCCAA CCTCAG chr20:47547498-47547578 51 8.34e-04 atgctacaga gaggtcaa gtgaggtaaa chr17:38668524-38668604 58 8.34e-04 GGGGTCACCT GGGGACAG AGGGAGATGG chr7:106424691-106424771 40 8.85e-04 ctttaaagaa gaggaCAA GATGCCAGAT chr17:57862775-57862855 20 9.15e-04 agcactttgg gaggccaa ggcaggtgga chr4:6809524-6809604 37 9.15e-04 agcactttgg gaggccaa ggcaagtgga chr1:28276703-28276783 68 9.46e-04 TCTTCCAGCA GGGGTCAA ACCAG chr2:191272512-191272592 32 1.04e-03 CGGGTCAACC TGGGACAG ACGCGGAGAT chr1:23977848-23977928 42 1.09e-03 AGGAAAAGTC TGGGCCAG CTGAGACACT chr13:95948799-95948879 56 1.09e-03 CCACTTTCTG TGGGCCAG ATGCATCTGG chr22:50701532-50701612 15 1.09e-03 AGACCCAAGC AAGGGCAC AGACTGTCCC chr2:196996190-196996270 17 1.17e-03 gcttttggca aagggcat acaaggtcgc -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif RRGGHCAY MEME-4 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr11:86714163-86714243 1.5e-05 53_[+4]_19 chr18:616504-616584 1.5e-05 19_[+4]_53 chr6:90049500-90049580 1.5e-05 1_[+4]_71 chr5:6544097-6544177 1.5e-05 45_[+4]_27 chr8:128876448-128876528 2.9e-05 52_[+4]_20 chr2:232046798-232046878 2.9e-05 50_[+4]_22 chr6:144851391-144851471 2.9e-05 68_[+4]_4 chr6:83716223-83716303 2.9e-05 19_[+4]_53 chr2:62422806-62422886 4.5e-05 32_[+4]_40 chr6:43464519-43464599 4.5e-05 15_[+4]_57 chr9:93949239-93949319 4.5e-05 30_[+4]_42 chr15:40430148-40430228 4.5e-05 26_[+4]_46 chr4:139867604-139867684 4.5e-05 61_[+4]_11 chr2:170408187-170408267 7.5e-05 28_[+4]_44 chr3:6686419-6686499 7.5e-05 40_[+4]_32 chr7:66691561-66691641 0.0001 38_[+4]_34 chr19:45417108-45417188 0.0001 21_[+4]_51 chr12:110368653-11036873 0.0001 14_[+4]_58 chr5:86405756-86405836 0.0001 24_[+4]_48 chr19:45429675-45429755 0.0001 10_[+4]_62 chr3:50628467-50628547 0.00014 14_[+4]_58 chr3:169850325-169850405 0.00014 53_[+4]_19 chr4:169937255-169937335 0.00014 27_[+4]_45 chr11:18032884-18032964 0.00014 42_[+4]_30 chr10:65181538-65181618 0.00014 27_[+4]_45 chr16:47181139-47181219 0.00014 58_[+4]_14 chr8:105542641-105542721 0.00014 40_[+4]_32 chr3:71419511-71419591 0.00017 44_[+4]_28 chr7:140375287-140375367 0.00017 71_[+4]_1 chr12:25428870-25428950 0.00017 16_[+4]_56 chr10:99503356-99503436 0.00017 1_[+4]_71 chr6:16241744-16241824 0.00017 44_[+4]_28 chr11:46231747-46231827 0.0002 43_[+4]_29 chr6:26012519-26012599 0.0002 53_[+4]_19 chr1:28116138-28116218 0.00023 37_[+4]_35 chr12:49657293-49657373 0.00023 1_[+4]_71 chr10:6076115-6076195 0.00028 22_[+4]_50 chr1:40121420-40121500 0.00028 46_[+4]_26 chr22:46402457-46402537 0.00028 19_[+4]_53 chr4:7034261-7034341 0.00028 55_[+4]_17 chr6:167177693-167177773 0.00038 47_[+4]_25 chr22:38077793-38077873 0.00038 70_[+4]_2 chr21:46256574-46256654 0.00043 4_[+4]_68 chr20:52407724-52407804 0.00043 69_[+4]_3 chr8:56765328-56765408 0.00043 11_[+4]_61 chr11:76572841-76572921 0.00043 30_[+4]_42 chr6:10315025-10315105 0.00049 11_[+4]_61 chr19:14618750-14618830 0.00049 55_[+4]_17 chr7:2996266-2996346 0.00049 52_[+4]_20 chr12:5330165-5330245 0.00049 60_[+4]_12 chr10:102823664-10282374 0.00049 43_[+4]_29 chr14:102094864-10209494 0.00049 68_[+4]_4 chr1:52830937-52831017 0.00055 54_[+4]_18 chr16:46782320-46782400 0.00061 17_[+4]_55 chr8:68989780-68989860 0.00061 62_[+4]_10 chr2:132419615-132419695 0.00061 43_[+4]_29 chr7:76000322-76000402 0.00061 11_[+4]_61 chr9:127704312-127704392 0.00061 26_[+4]_46 chr3:195581248-195581328 0.00061 25_[+4]_47 chr3:177315739-177315819 0.00061 16_[+4]_56 chr4:40918992-40919072 0.00067 61_[+4]_11 chr2:225350110-225350190 0.00067 20_[+4]_52 chrX:65709282-65709362 0.00067 64_[+4]_8 chr1:25543630-25543710 0.00067 66_[+4]_6 chr20:23161397-23161477 0.00067 15_[+4]_57 chr2:205299509-205299589 0.00074 23_[+4]_49 chr16:49654594-49654674 0.00079 50_[+4]_22 chr19:51568014-51568094 0.00079 66_[+4]_6 chr20:47547498-47547578 0.00083 50_[+4]_22 chr17:38668524-38668604 0.00083 57_[+4]_15 chr7:106424691-106424771 0.00088 39_[+4]_33 chr17:57862775-57862855 0.00092 19_[+4]_53 chr4:6809524-6809604 0.00092 36_[+4]_36 chr1:28276703-28276783 0.00095 67_[+4]_5 chr2:191272512-191272592 0.001 31_[+4]_41 chr1:23977848-23977928 0.0011 41_[+4]_31 chr13:95948799-95948879 0.0011 55_[+4]_17 chr22:50701532-50701612 0.0011 14_[+4]_58 chr2:196996190-196996270 0.0012 16_[+4]_56 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif RRGGHCAY MEME-4 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF RRGGHCAY width=8 seqs=79 chr11:86714163-86714243 ( 54) AAGGTCAC 1 chr18:616504-616584 ( 20) AAGGTCAC 1 chr6:90049500-90049580 ( 2) AAGGTCAC 1 chr5:6544097-6544177 ( 46) AAGGTCAC 1 chr8:128876448-128876528 ( 53) AAGGACAC 1 chr2:232046798-232046878 ( 51) AAGGACAC 1 chr6:144851391-144851471 ( 69) AAGGACAC 1 chr6:83716223-83716303 ( 20) AAGGACAC 1 chr2:62422806-62422886 ( 33) AAGGCCAC 1 chr6:43464519-43464599 ( 16) AAGGCCAC 1 chr9:93949239-93949319 ( 31) AAGGCCAC 1 chr15:40430148-40430228 ( 27) AAGGCCAC 1 chr4:139867604-139867684 ( 62) AAGGCCAC 1 chr2:170408187-170408267 ( 29) AGGGTCAC 1 chr3:6686419-6686499 ( 41) AAGGTCAT 1 chr7:66691561-66691641 ( 39) AGGGACAC 1 chr19:45417108-45417188 ( 22) AGGGACAC 1 chr12:110368653-11036873 ( 15) AAGGACAT 1 chr5:86405756-86405836 ( 25) AAGGACAT 1 chr19:45429675-45429755 ( 11) AGGGACAC 1 chr3:50628467-50628547 ( 15) AGGGCCAC 1 chr3:169850325-169850405 ( 54) AAGGCCAT 1 chr4:169937255-169937335 ( 28) AAGGCCAT 1 chr11:18032884-18032964 ( 43) AAGGCCAT 1 chr10:65181538-65181618 ( 28) AAGGCCAT 1 chr16:47181139-47181219 ( 59) AAGGCCAT 1 chr8:105542641-105542721 ( 41) AAGGCCAT 1 chr3:71419511-71419591 ( 45) GAGGTCAC 1 chr7:140375287-140375367 ( 72) AGGGTCAT 1 chr12:25428870-25428950 ( 17) GAGGTCAC 1 chr10:99503356-99503436 ( 2) AGGGTCAT 1 chr6:16241744-16241824 ( 45) AGGGTCAT 1 chr11:46231747-46231827 ( 44) GAGGACAC 1 chr6:26012519-26012599 ( 54) GAGGACAC 1 chr1:28116138-28116218 ( 38) AGGGCCAT 1 chr12:49657293-49657373 ( 2) AGGGCCAT 1 chr10:6076115-6076195 ( 23) GAGGTCAT 1 chr1:40121420-40121500 ( 47) AAGGTCAG 1 chr22:46402457-46402537 ( 20) GGGGTCAC 1 chr4:7034261-7034341 ( 56) GGGGTCAC 1 chr6:167177693-167177773 ( 48) AAGGCCAG 1 chr22:38077793-38077873 ( 71) GGGGCCAC 1 chr21:46256574-46256654 ( 5) TAGGTCAC 1 chr20:52407724-52407804 ( 70) AGGGTCAG 1 chr8:56765328-56765408 ( 12) TAGGTCAC 1 chr11:76572841-76572921 ( 31) GGGGTCAT 1 chr6:10315025-10315105 ( 12) GGGGACAT 1 chr19:14618750-14618830 ( 56) GGGGACAT 1 chr7:2996266-2996346 ( 53) GGGGACAT 1 chr12:5330165-5330245 ( 61) AGGGACAG 1 chr10:102823664-10282374 ( 44) AGGGACAG 1 chr14:102094864-10209494 ( 69) GGGGACAT 1 chr1:52830937-52831017 ( 55) GGGGCCAT 1 chr16:46782320-46782400 ( 18) GAGGTCAG 1 chr8:68989780-68989860 ( 63) TGGGTCAC 1 chr2:132419615-132419695 ( 44) TAGGTCAT 1 chr7:76000322-76000402 ( 12) AAGGCCAA 1 chr9:127704312-127704392 ( 27) GAGGTCAG 1 chr3:195581248-195581328 ( 26) TGGGTCAC 1 chr3:177315739-177315819 ( 17) TGGGTCAC 1 chr4:40918992-40919072 ( 62) AGGGTCAA 1 chr2:225350110-225350190 ( 21) TGGGACAC 1 chrX:65709282-65709362 ( 65) TGGGACAC 1 chr1:25543630-25543710 ( 67) GAGGACAG 1 chr20:23161397-23161477 ( 16) TGGGACAC 1 chr2:205299509-205299589 ( 24) GAGGCCAG 1 chr16:49654594-49654674 ( 51) TGGGTCAT 1 chr19:51568014-51568094 ( 67) AGGGCCAA 1 chr20:47547498-47547578 ( 51) GAGGTCAA 1 chr17:38668524-38668604 ( 58) GGGGACAG 1 chr7:106424691-106424771 ( 40) GAGGACAA 1 chr17:57862775-57862855 ( 20) GAGGCCAA 1 chr4:6809524-6809604 ( 37) GAGGCCAA 1 chr1:28276703-28276783 ( 68) GGGGTCAA 1 chr2:191272512-191272592 ( 32) TGGGACAG 1 chr1:23977848-23977928 ( 42) TGGGCCAG 1 chr13:95948799-95948879 ( 56) TGGGCCAG 1 chr22:50701532-50701612 ( 15) AAGGGCAC 1 chr2:196996190-196996270 ( 17) AAGGGCAT 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif RRGGHCAY MEME-4 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 8.78077 E= 2.6e-005 117 -1295 22 -55 121 -1295 81 -1295 -1295 -1295 194 -1295 -1295 -1295 194 -1295 37 21 -336 60 -1295 193 -1295 -1295 209 -1295 -1295 -1295 -122 71 -66 33 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif RRGGHCAY MEME-4 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 79 E= 2.6e-005 0.531646 0.000000 0.303797 0.164557 0.544304 0.000000 0.455696 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.303797 0.303797 0.025316 0.367089 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.101266 0.430380 0.164557 0.303797 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif RRGGHCAY MEME-4 regular expression -------------------------------------------------------------------------------- [AG][AG]GG[TAC]CA[CT] -------------------------------------------------------------------------------- Time 15.30 secs. ******************************************************************************** ******************************************************************************** MOTIF TTTTAGTA MEME-5 width = 8 sites = 10 llr = 107 E-value = 1.9e+001 ******************************************************************************** -------------------------------------------------------------------------------- Motif TTTTAGTA MEME-5 Description -------------------------------------------------------------------------------- Simplified A ::::9::9 pos.-specific C :::::::: probability G :::::a:1 matrix T aaaa1:a: bits 2.1 **** * 1.9 **** ** 1.7 ******** 1.5 ******** Relative 1.3 ******** Entropy 1.0 ******** (15.4 bits) 0.8 ******** 0.6 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel TTTTAGTA consensus sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTTTAGTA MEME-5 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr19:14618750-14618830 65 1.20e-05 GGGGGACATT TTTTAGTA TTCTCCTG chr6:14691379-14691459 12 1.20e-05 ttttttgtat ttttagta gagaccgggt chr2:9835792-9835872 2 1.20e-05 t ttttagta gagatggggt chr7:8273158-8273238 44 1.20e-05 ttttgtatgt ttttagta cagatggggt chr19:8488109-8488189 17 1.20e-05 ttttgtattt ttttagta gagacggggt chr19:34753366-34753446 11 1.20e-05 atttttgtat ttttagta gagatggggt chr19:45245754-45245834 54 1.20e-05 agttttgtat ttttagta gagacggggt chr22:17518847-17518927 38 1.20e-05 gtatttttat ttttagta gagacggggt chr5:118656359-118656439 13 2.43e-05 cttctttttc tttttgta gtatgacctt chr6:167177693-167177773 61 3.76e-05 GCCAGCGACA TTTTAGTG ATGGGCAGAG -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTTTAGTA MEME-5 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr19:14618750-14618830 1.2e-05 64_[+5]_8 chr6:14691379-14691459 1.2e-05 11_[+5]_61 chr2:9835792-9835872 1.2e-05 1_[+5]_71 chr7:8273158-8273238 1.2e-05 43_[+5]_29 chr19:8488109-8488189 1.2e-05 16_[+5]_56 chr19:34753366-34753446 1.2e-05 10_[+5]_62 chr19:45245754-45245834 1.2e-05 53_[+5]_19 chr22:17518847-17518927 1.2e-05 37_[+5]_35 chr5:118656359-118656439 2.4e-05 12_[+5]_60 chr6:167177693-167177773 3.8e-05 60_[+5]_12 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTTTAGTA MEME-5 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF TTTTAGTA width=8 seqs=10 chr19:14618750-14618830 ( 65) TTTTAGTA 1 chr6:14691379-14691459 ( 12) TTTTAGTA 1 chr2:9835792-9835872 ( 2) TTTTAGTA 1 chr7:8273158-8273238 ( 44) TTTTAGTA 1 chr19:8488109-8488189 ( 17) TTTTAGTA 1 chr19:34753366-34753446 ( 11) TTTTAGTA 1 chr19:45245754-45245834 ( 54) TTTTAGTA 1 chr22:17518847-17518927 ( 38) TTTTAGTA 1 chr5:118656359-118656439 ( 13) TTTTTGTA 1 chr6:167177693-167177773 ( 61) TTTTAGTG 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTTTAGTA MEME-5 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 11.0846 E= 1.9e+001 -997 -997 -997 205 -997 -997 -997 205 -997 -997 -997 205 -997 -997 -997 205 193 -997 -997 -127 -997 -997 194 -997 -997 -997 -997 205 193 -997 -138 -997 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTTTAGTA MEME-5 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 10 E= 1.9e+001 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.900000 0.000000 0.000000 0.100000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.900000 0.000000 0.100000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTTTAGTA MEME-5 regular expression -------------------------------------------------------------------------------- TTTTAGTA -------------------------------------------------------------------------------- Time 18.57 secs. ******************************************************************************** ******************************************************************************** SUMMARY OF MOTIFS ******************************************************************************** -------------------------------------------------------------------------------- Combined block diagrams: non-overlapping sites with p-value < 0.0001 -------------------------------------------------------------------------------- SEQUENCE NAME COMBINED P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr22:50327878-50327958 2.21e-02 52_[+1(9.17e-05)]_20 chr19:10426988-10427068 3.91e-03 54_[+4(7.47e-05)]_18 chr20:23161397-23161477 2.06e-02 3_[+2(7.09e-05)]_69 chr1:25543630-25543710 2.48e-02 80 chr4:139867604-139867684 2.14e-02 61_[+4(4.48e-05)]_11 chrX:39992201-39992281 3.78e-02 80 chr22:38077793-38077873 2.00e-02 6_[+1(9.17e-05)]_66 chr6:16241744-16241824 8.37e-03 80 chr5:146345813-146345893 3.56e-02 80 chr10:99503356-99503436 2.10e-02 80 chr15:68190143-68190223 2.00e-03 23_[+1(9.17e-05)]_1_[+3(6.03e-05)]_\ 40 chr7:55640628-55640708 1.45e-01 80 chr17:7739613-7739693 6.20e-01 80 chr6:47215031-47215111 1.61e-03 80 chr6:83716223-83716303 2.43e-02 19_[+4(2.89e-05)]_53 chr17:62832862-62832942 3.12e-02 80 chr3:6686419-6686499 1.53e-04 40_[+4(7.47e-05)]_32 chr11:63712601-63712681 1.81e-01 80 chr6:17966222-17966302 2.05e-02 4_[+2(3.64e-05)]_68 chr1:14136400-14136480 4.82e-04 57_[+1(9.17e-05)]_1_[+3(1.40e-05)]_\ 6 chr16:11892392-11892472 1.57e-02 60_[+3(1.40e-05)]_12 chr12:117507404-11750748 1.57e-01 46_[+1(9.17e-05)]_26 chr4:7034261-7034341 2.59e-03 43_[+3(2.91e-05)]_29 chr22:17518847-17518927 2.33e-03 22_[+5(2.43e-05)]_7_[+5(1.20e-05)]_\ 23_[+2(7.09e-05)]_4 chr4:174363892-174363972 6.17e-01 80 chr19:2168289-2168369 3.18e-01 80 chr4:174968777-174968857 6.74e-03 80 chr16:28608342-28608422 6.08e-01 80 chr4:185668249-185668329 1.16e-03 33_[+1(3.03e-05)]_39 chrX:71933570-71933650 7.14e-01 80 chr2:191272512-191272592 3.37e-01 80 chr20:23641150-23641230 6.23e-01 80 chr6:26155980-26156060 2.24e-01 80 chr8:41670720-41670800 1.11e-01 80 chr6:144851391-144851471 2.63e-03 23_[+1(9.17e-05)]_37_[+4(2.89e-05)]_\ 4 chr18:8610444-8610524 1.33e-02 72_[+1(3.03e-05)] chr12:118726183-11872626 6.92e-03 80 chr22:50701532-50701612 2.82e-03 61_[+3(9.39e-05)]_11 chr1:25605005-25605085 2.51e-02 38_[+1(3.03e-05)]_34 chr5:6544097-6544177 8.77e-03 45_[+4(1.47e-05)]_27 chr11:76572841-76572921 4.34e-02 80 chr6:34663363-34663443 1.05e-01 80 chr5:135524770-135524850 1.04e-02 10_[+1(9.17e-05)]_1_[+3(6.03e-05)]_\ 53 chr6:107443358-107443438 1.98e-02 70_[+1(6.05e-05)]_2 chr20:33126639-33126719 1.31e-01 80 chr17:34193586-34193666 2.01e-01 80 chr3:195951289-195951369 2.13e-02 59_[+1(6.05e-05)]_13 chr6:10489424-10489504 4.28e-02 3_[+3(1.40e-05)]_69 chr19:45245754-45245834 3.51e-02 53_[+5(1.20e-05)]_19 chr19:34753366-34753446 1.01e-04 1_[+5(2.43e-05)]_1_[+5(1.20e-05)]_\ 43_[+1(3.03e-05)]_11 chr1:246536048-246536128 3.59e-03 27_[+1(6.05e-05)]_45 chr20:22567512-22567592 9.75e-01 80 chr11:96012954-96013034 1.51e-01 80 chr19:8439160-8439240 4.29e-02 80 chr9:73035192-73035272 7.30e-01 80 chr2:46525661-46525741 5.61e-02 48_[+3(9.39e-05)]_24 chr12:25428870-25428950 8.28e-05 15_[+1(6.05e-05)]_2_[+1(6.05e-05)]_\ 11_[+2(3.64e-05)]_28 chr2:232046798-232046878 3.77e-02 50_[+4(2.89e-05)]_22 chr3:112532046-112532126 9.06e-03 45_[+1(9.17e-05)]_2_[+1(3.03e-05)]_\ 17 chr20:23095847-23095927 4.07e-05 4_[+2(1.82e-05)]_12_[+1(3.03e-05)]_\ 48 chrX:2451529-2451609 1.44e-03 8_[+1(9.17e-05)]_14_[+2(3.64e-05)]_\ 42 chr1:183462912-183462992 5.75e-04 9_[+2(1.82e-05)]_12_[+1(3.03e-05)]_\ 43 chr11:34621306-34621386 1.52e-01 80 chr14:102094864-10209494 6.77e-04 32_[+3(9.39e-05)]_40 chr8:117557410-117557490 2.18e-03 27_[+1(9.17e-05)]_9_[+2(7.09e-05)]_\ 28 chr5:81069545-81069625 1.62e-03 9_[+2(3.64e-05)]_47_[+3(2.91e-05)]_\ 8 chr19:7957489-7957569 2.01e-01 80 chr22:46402457-46402537 2.74e-01 80 chr20:32418321-32418401 1.51e-03 28_[+1(9.17e-05)]_1_[+3(6.03e-05)]_\ 35 chr6:167177693-167177773 2.33e-04 60_[+5(3.76e-05)]_12 chr1:166668134-166668214 1.27e-01 80 chr10:102823664-10282374 3.14e-02 80 chr8:105542641-105542721 1.02e-02 80 chr9:36573687-36573767 2.45e-03 23_[+2(1.82e-05)]_12_[+1(9.17e-05)]_\ 29 chr9:97788185-97788265 2.00e-01 80 chr3:177315739-177315819 6.21e-02 80 chr2:65449181-65449261 1.14e-01 80 chr9:134188580-134188660 4.86e-01 80 chrX:154365885-154365965 1.24e-03 [+2(7.09e-05)]_13_[+1(3.03e-05)]_51 chr13:95948799-95948879 6.33e-02 80 chr12:67949353-67949433 2.69e-02 10_[+1(3.03e-05)]_62 chr19:8488109-8488189 2.89e-06 5_[+5(2.43e-05)]_3_[+5(1.20e-05)]_\ 23_[+2(7.09e-05)]_6_[+1(3.03e-05)]_11 chr15:40430148-40430228 1.31e-02 26_[+4(4.48e-05)]_46 chr2:10148707-10148787 7.80e-02 8_[+2(7.09e-05)]_64 chr6:35778949-35779029 3.41e-01 80 chr4:83332210-83332290 6.31e-02 8_[+3(6.03e-05)]_64 chr12:56661358-56661438 2.80e-01 80 chr3:49481573-49481653 1.06e-01 80 chr9:93949239-93949319 2.42e-03 30_[+4(4.48e-05)]_42 chr1:227581236-227581316 1.47e-03 8_[+1(6.05e-05)]_64 chr5:180588657-180588737 2.58e-02 56_[+1(3.03e-05)]_16 chr16:47181139-47181219 1.25e-02 80 chr4:6809524-6809604 4.92e-04 59_[+1(6.05e-05)]_5_[+2(3.64e-05)] chrX:65709282-65709362 1.23e-02 53_[+1(6.05e-05)]_19 chr11:62728619-62728699 1.01e-01 80 chr16:21275686-21275766 3.67e-04 5_[+1(6.05e-05)]_20_[+2(7.09e-05)]_\ 39 chr17:1696846-1696926 3.00e-01 80 chr9:86602174-86602254 3.24e-02 20_[+1(3.03e-05)]_52 chr8:56765328-56765408 1.71e-04 20_[+1(6.05e-05)]_11_[+2(3.64e-05)]_\ 33 chr5:56738385-56738465 1.57e-02 80 chr4:57378473-57378553 3.98e-01 80 chr10:65181538-65181618 4.73e-03 80 chr22:41213187-41213267 5.50e-01 80 chr15:51964720-51964800 7.24e-01 80 chr3:195581248-195581328 9.22e-04 34_[+1(6.05e-05)]_38 chr22:43560102-43560182 4.00e-01 80 chr6:15491811-15491891 3.28e-02 80 chr11:18032884-18032964 3.47e-02 80 chr3:58950000-58950080 1.26e-01 80 chr19:55193983-55194063 3.10e-01 80 chr2:196996190-196996270 1.10e-01 80 chr2:170408187-170408267 1.47e-03 28_[+4(7.47e-05)]_1_[+1(6.05e-05)]_\ 35 chr8:128876448-128876528 5.87e-02 52_[+4(2.89e-05)]_20 chr9:14538689-14538769 1.95e-01 80 chr11:47961353-47961433 5.11e-04 12_[+1(6.05e-05)]_11_[+2(3.64e-05)]_\ 41 chr19:3986358-3986438 3.56e-01 80 chr5:130943429-130943509 8.45e-02 80 chr2:114361131-114361211 5.02e-02 80 chr3:15404182-15404262 7.97e-01 80 chr4:68579994-68580074 9.61e-01 80 chr20:19983387-19983467 6.60e-03 22_[+1(9.17e-05)]_50 chr11:5249089-5249169 4.83e-02 80 chr6:43464519-43464599 1.71e-03 15_[+4(4.48e-05)]_57 chr1:40121420-40121500 2.72e-02 80 chr6:11093490-11093570 1.93e-01 80 chr3:14416863-14416943 1.50e-02 38_[+1(6.05e-05)]_34 chr3:177051983-177052063 1.47e-02 47_[+1(6.05e-05)]_25 chr4:169937255-169937335 1.99e-02 80 chr16:84076922-84077002 5.07e-01 80 chr2:114649712-114649792 1.25e-01 80 chr17:71027894-71027974 2.80e-03 10_[+2(7.09e-05)]_62 chr3:171679313-171679393 7.29e-02 37_[+3(9.39e-05)]_35 chr15:49271002-49271082 1.13e-03 30_[+1(9.17e-05)]_1_[+3(1.40e-05)]_\ 33 chr17:7197341-7197421 7.10e-01 80 chr19:51568014-51568094 2.75e-01 80 chr7:140020068-140020148 4.39e-01 80 chr7:8273158-8273238 2.20e-02 32_[+5(2.43e-05)]_3_[+5(1.20e-05)]_\ 29 chr17:60258289-60258369 2.81e-03 6_[+1(6.05e-05)]_66 chr12:5330165-5330245 7.07e-02 80 chr9:73034183-73034263 9.19e-01 80 chr2:178544693-178544773 9.37e-04 80 chr19:45429675-45429755 2.13e-02 80 chr16:9221554-9221634 5.15e-03 54_[+1(6.05e-05)]_18 chr1:15501232-15501312 4.15e-01 80 chr12:23208130-23208210 4.76e-02 80 chr6:26012519-26012599 1.33e-02 18_[+1(6.05e-05)]_54 chr9:127704312-127704392 1.40e-01 80 chr6:126245541-126245621 8.21e-03 80 chr2:103352300-103352380 9.84e-01 80 chr1:52830937-52831017 9.45e-03 80 chr1:211546006-211546086 6.51e-02 80 chr3:172259239-172259319 8.82e-04 63_[+1(6.05e-05)]_9 chr5:86405756-86405836 2.10e-02 80 chr2:9835792-9835872 6.66e-07 1_[+5(1.20e-05)]_23_[+2(1.82e-05)]_\ 12_[+1(3.03e-05)]_20 chr11:75186750-75186830 2.33e-02 8_[+1(3.03e-05)]_64 chr11:68103313-68103393 2.23e-02 17_[+1(3.03e-05)]_55 chr5:118656359-118656439 3.70e-04 12_[+5(2.43e-05)]_2_[+3(1.40e-05)]_\ 50 chr6:14454314-14454394 2.90e-03 26_[+1(9.17e-05)]_1_[+3(6.03e-05)]_\ 37 chr17:18075988-18076068 6.40e-03 14_[+1(9.17e-05)]_3_[+1(9.17e-05)]_\ 1_[+3(6.03e-05)]_38 chr2:24846603-24846683 5.10e-02 16_[+1(9.17e-05)]_56 chr11:46736121-46736201 1.67e-02 16_[+1(3.03e-05)]_56 chr12:29408165-29408245 7.69e-02 19_[+1(9.17e-05)]_53 chr9:133397833-133397913 3.40e-01 80 chr6:90049500-90049580 2.05e-04 1_[+4(1.47e-05)]_20_[+2(3.64e-05)]_\ 43 chr21:47368809-47368889 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chr3:72067678-72067758 7.26e-02 80 chr4:140135399-140135479 7.78e-03 12_[+1(9.17e-05)]_1_[+3(6.03e-05)]_\ 51 chr7:106424691-106424771 1.83e-01 80 chr3:148803951-148804031 6.95e-01 80 chr1:161347043-161347123 4.02e-01 80 chr4:40918992-40919072 1.29e-01 80 chr16:46782320-46782400 3.63e-02 80 chr2:62422806-62422886 6.21e-02 32_[+4(4.48e-05)]_40 chr22:22391808-22391888 2.82e-02 63_[+1(3.03e-05)]_9 chr1:206592852-206592932 2.22e-02 18_[+3(9.39e-05)]_54 chrX:118603425-118603505 2.02e-01 80 chr11:119312115-11931219 1.13e-01 80 chr20:39636874-39636954 9.84e-02 80 chr3:170530961-170531041 4.93e-03 80 chr11:46231747-46231827 1.09e-03 1_[+3(6.03e-05)]_71 chr2:172078322-172078402 2.59e-01 80 chr22:50607371-50607451 8.81e-01 80 chr1:28276703-28276783 4.68e-02 35_[+2(7.09e-05)]_37 chr7:66691561-66691641 1.88e-03 80 chr22:23319307-23319387 4.36e-01 80 chr16:49654594-49654674 3.94e-02 80 -------------------------------------------------------------------------------- ******************************************************************************** ******************************************************************************** Stopped because requested number of motifs (5) found. ******************************************************************************** CPU: c22n04.farnam.hpc.yale.internal ********************************************************************************