******************************************************************************** MEME - Motif discovery tool ******************************************************************************** MEME version 5.3.3 (Release date: Sun Feb 7 15:39:52 2021 -0800) For further information on how to interpret these results please access https://meme-suite.org/meme. To get a copy of the MEME Suite software please access https://meme-suite.org. ******************************************************************************** ******************************************************************************** REFERENCE ******************************************************************************** If you use this program in your research, please cite: Timothy L. Bailey and Charles Elkan, "Fitting a mixture model by expectation maximization to discover motifs in biopolymers", Proceedings of the Second International Conference on Intelligent Systems for Molecular Biology, pp. 28-36, AAAI Press, Menlo Park, California, 1994. ******************************************************************************** ******************************************************************************** TRAINING SET ******************************************************************************** PRIMARY SEQUENCES= ../result/final_prediction/K562/fasta/RankLinear0.6_40/TEAD4.fasta CONTROL SEQUENCES= --none-- ALPHABET= ACGT Sequence name Weight Length Sequence name Weight Length ------------- ------ ------ ------------- ------ ------ chr9:101553585-101553665 1.0000 80 chr1:234740753-234740833 1.0000 80 chr1:214176684-214176764 1.0000 80 chr4:151695355-151695435 1.0000 80 chr11:85753088-85753168 1.0000 80 chr9:96974547-96974627 1.0000 80 chr1:95100703-95100783 1.0000 80 chr15:67066819-67066899 1.0000 80 chr5:95220353-95220433 1.0000 80 chr7:132174696-132174776 1.0000 80 chr3:16977884-16977964 1.0000 80 chr13:44961220-44961300 1.0000 80 chr6:152554103-152554183 1.0000 80 chr2:30476952-30477032 1.0000 80 chr6:74238821-74238901 1.0000 80 chr7:5123117-5123197 1.0000 80 chr5:158555218-158555298 1.0000 80 chr7:127627082-127627162 1.0000 80 chr5:10708805-10708885 1.0000 80 chr8:23526275-23526355 1.0000 80 chr1:51186307-51186387 1.0000 80 chr7:24903968-24904048 1.0000 80 chr10:63540244-63540324 1.0000 80 chr4:103277024-103277104 1.0000 80 chr6:150881280-150881360 1.0000 80 chr7:66387286-66387366 1.0000 80 chr12:65114788-65114868 1.0000 80 chr3:137918873-137918953 1.0000 80 chr2:37843915-37843995 1.0000 80 chr5:178110934-178111014 1.0000 80 chr19:13694065-13694145 1.0000 80 chr5:111885581-111885661 1.0000 80 chr13:44972150-44972230 1.0000 80 chr2:68220641-68220721 1.0000 80 chrX:55054603-55054683 1.0000 80 chr1:206274318-206274398 1.0000 80 chrX:119468577-119468657 1.0000 80 chr1:48643126-48643206 1.0000 80 chr2:27197335-27197415 1.0000 80 chr8:2645835-2645915 1.0000 80 chr1:53647831-53647911 1.0000 80 chr4:25052511-25052591 1.0000 80 chr9:7067327-7067407 1.0000 80 chr1:26087554-26087634 1.0000 80 chr6:109606071-109606151 1.0000 80 chr17:33212288-33212368 1.0000 80 chrX:107801631-107801711 1.0000 80 chr10:82531902-82531982 1.0000 80 chr20:37192564-37192644 1.0000 80 chr1:214593156-214593236 1.0000 80 chr11:68899174-68899254 1.0000 80 chr1:45362178-45362258 1.0000 80 chrX:39011780-39011860 1.0000 80 chrX:109202815-109202895 1.0000 80 chr1:230341606-230341686 1.0000 80 chr2:48679410-48679490 1.0000 80 chr1:70005901-70005981 1.0000 80 chr12:60538339-60538419 1.0000 80 chr8:106532850-106532930 1.0000 80 chr8:49379267-49379347 1.0000 80 chr8:21366961-21367041 1.0000 80 chr1:156430427-156430507 1.0000 80 chr3:148951296-148951376 1.0000 80 chr20:35783242-35783322 1.0000 80 chr11:47026414-47026494 1.0000 80 chr11:82503034-82503114 1.0000 80 chr4:95574450-95574530 1.0000 80 chr1:95113903-95113983 1.0000 80 chr4:160116714-160116794 1.0000 80 chr13:99628332-99628412 1.0000 80 chr15:93461232-93461312 1.0000 80 chr21:32754500-32754580 1.0000 80 chr1:222883255-222883335 1.0000 80 chr6:19968588-19968668 1.0000 80 chr2:217957626-217957706 1.0000 80 chr2:42423647-42423727 1.0000 80 chr5:168240747-168240827 1.0000 80 chr19:16308205-16308285 1.0000 80 chr5:131987918-131987998 1.0000 80 chr19:54770069-54770149 1.0000 80 chrX:134996735-134996815 1.0000 80 chr7:148545022-148545102 1.0000 80 chr2:15696580-15696660 1.0000 80 chr8:67967436-67967516 1.0000 80 chr7:37397333-37397413 1.0000 80 chr4:79405857-79405937 1.0000 80 chr2:178504405-178504485 1.0000 80 chr22:40725269-40725349 1.0000 80 chr6:21102063-21102143 1.0000 80 chr18:33039029-33039109 1.0000 80 chr20:5469588-5469668 1.0000 80 chrX:37512276-37512356 1.0000 80 chr2:178939662-178939742 1.0000 80 chr2:46666870-46666950 1.0000 80 chr9:86958274-86958354 1.0000 80 chr3:156178167-156178247 1.0000 80 chr6:20575569-20575649 1.0000 80 chrX:122598706-122598786 1.0000 80 chr3:10020821-10020901 1.0000 80 chr12:21966225-21966305 1.0000 80 chr3:133472769-133472849 1.0000 80 chr14:31291369-31291449 1.0000 80 chr5:169514580-169514660 1.0000 80 chr7:117581637-117581717 1.0000 80 chr4:99603973-99604053 1.0000 80 chr6:164767864-164767944 1.0000 80 chr6:15922902-15922982 1.0000 80 chr6:140069947-140070027 1.0000 80 chr18:67692991-67693071 1.0000 80 chr8:56926571-56926651 1.0000 80 chr1:168257599-168257679 1.0000 80 chr7:119566125-119566205 1.0000 80 chr4:10347164-10347244 1.0000 80 chr12:28345227-28345307 1.0000 80 chr13:39573051-39573131 1.0000 80 chrX:49963276-49963356 1.0000 80 chr1:209819337-209819417 1.0000 80 chr22:30348257-30348337 1.0000 80 chr9:125016706-125016786 1.0000 80 chr1:204196621-204196701 1.0000 80 chr5:89954577-89954657 1.0000 80 chr10:75913048-75913128 1.0000 80 chr15:31270673-31270753 1.0000 80 chr9:130188248-130188328 1.0000 80 chr15:50886658-50886738 1.0000 80 chr15:57675325-57675405 1.0000 80 chr9:114856005-114856085 1.0000 80 chr1:101251443-101251523 1.0000 80 chr2:160353944-160354024 1.0000 80 chr14:75177348-75177428 1.0000 80 chr3:32750308-32750388 1.0000 80 chr1:246588580-246588660 1.0000 80 chr1:95581328-95581408 1.0000 80 chr10:17045278-17045358 1.0000 80 chr1:179941155-179941235 1.0000 80 chr20:9129850-9129930 1.0000 80 chr17:33214019-33214099 1.0000 80 chr15:64731399-64731479 1.0000 80 chr3:151444006-151444086 1.0000 80 chr2:64582057-64582137 1.0000 80 chr14:55850704-55850784 1.0000 80 chr12:89787579-89787659 1.0000 80 chr16:50105138-50105218 1.0000 80 chr4:81174848-81174928 1.0000 80 chr16:21272959-21273039 1.0000 80 chr16:8688297-8688377 1.0000 80 chr8:96939401-96939481 1.0000 80 chr1:109677204-109677284 1.0000 80 chr16:66651869-66651949 1.0000 80 chrX:10127231-10127311 1.0000 80 chr6:13355805-13355885 1.0000 80 chr10:127293911-12729399 1.0000 80 chr1:206266182-206266262 1.0000 80 chr1:213779222-213779302 1.0000 80 chr6:119863407-119863487 1.0000 80 chr5:29796337-29796417 1.0000 80 chrX:99998389-99998469 1.0000 80 chr6:126439349-126439429 1.0000 80 chr10:96059329-96059409 1.0000 80 chr2:158755879-158755959 1.0000 80 chrX:47676964-47677044 1.0000 80 chr2:145978784-145978864 1.0000 80 chr4:10013706-10013786 1.0000 80 chr7:10747317-10747397 1.0000 80 chr6:80314395-80314475 1.0000 80 chr3:154736918-154736998 1.0000 80 chr20:30082073-30082153 1.0000 80 chr12:92798843-92798923 1.0000 80 chr16:25783255-25783335 1.0000 80 chr14:65509912-65509992 1.0000 80 chr3:170079718-170079798 1.0000 80 chr6:159920213-159920293 1.0000 80 chr16:22227757-22227837 1.0000 80 chr6:32256394-32256474 1.0000 80 chr10:14223352-14223432 1.0000 80 chr8:97656729-97656809 1.0000 80 chr3:142337811-142337891 1.0000 80 chr9:90419029-90419109 1.0000 80 chr8:131355454-131355534 1.0000 80 chr7:116079238-116079318 1.0000 80 chr15:92021984-92022064 1.0000 80 chr16:55469427-55469507 1.0000 80 chr3:182502499-182502579 1.0000 80 chr4:99608149-99608229 1.0000 80 chr17:57762504-57762584 1.0000 80 chr3:105333306-105333386 1.0000 80 chr1:45501483-45501563 1.0000 80 chr18:75034062-75034142 1.0000 80 chr6:4177221-4177301 1.0000 80 chr3:143734116-143734196 1.0000 80 chr3:42391380-42391460 1.0000 80 chr15:35459071-35459151 1.0000 80 chr4:87975693-87975773 1.0000 80 chr4:122715802-122715882 1.0000 80 chr2:10533327-10533407 1.0000 80 chr11:422363-422443 1.0000 80 chrX:40403744-40403824 1.0000 80 chr10:121904786-12190486 1.0000 80 chr10:62022655-62022735 1.0000 80 chr11:67116039-67116119 1.0000 80 chr7:104607697-104607777 1.0000 80 chr22:40718275-40718355 1.0000 80 chr11:59735657-59735737 1.0000 80 chrX:130086522-130086602 1.0000 80 chr4:129268783-129268863 1.0000 80 chr8:86290464-86290544 1.0000 80 chr15:84131789-84131869 1.0000 80 chr16:81254217-81254297 1.0000 80 chr19:14253631-14253711 1.0000 80 chr4:155377536-155377616 1.0000 80 chr6:138172498-138172578 1.0000 80 chr11:108094347-10809442 1.0000 80 chr7:135718340-135718420 1.0000 80 chr2:32993554-32993634 1.0000 80 chr15:39432297-39432377 1.0000 80 chr7:102082193-102082273 1.0000 80 chr20:20927143-20927223 1.0000 80 chr3:71257577-71257657 1.0000 80 chr2:74311079-74311159 1.0000 80 chr8:87522864-87522944 1.0000 80 chr9:127727085-127727165 1.0000 80 chrX:55041562-55041642 1.0000 80 chr4:109035778-109035858 1.0000 80 chr1:206909005-206909085 1.0000 80 chr7:115858315-115858395 1.0000 80 chr3:179093055-179093135 1.0000 80 chr4:96210548-96210628 1.0000 80 chr20:42639110-42639190 1.0000 80 chr20:32007090-32007170 1.0000 80 chr10:126406632-12640671 1.0000 80 chr3:98302731-98302811 1.0000 80 chr8:23366395-23366475 1.0000 80 chr4:184162517-184162597 1.0000 80 chr5:148127233-148127313 1.0000 80 chrX:45024397-45024477 1.0000 80 chr1:39210366-39210446 1.0000 80 chr6:123033599-123033679 1.0000 80 chr4:20700585-20700665 1.0000 80 chr7:39849958-39850038 1.0000 80 chr5:148126515-148126595 1.0000 80 chr7:134519773-134519853 1.0000 80 chr7:44120948-44121028 1.0000 80 chr3:196715537-196715617 1.0000 80 chr5:89940129-89940209 1.0000 80 chr2:58349849-58349929 1.0000 80 chr2:84198848-84198928 1.0000 80 chr6:161665886-161665966 1.0000 80 chr6:108880388-108880468 1.0000 80 chrX:107463299-107463379 1.0000 80 chr9:131355491-131355571 1.0000 80 ******************************************************************************** ******************************************************************************** COMMAND LINE SUMMARY ******************************************************************************** This information can also be useful in the event you wish to report a problem with the MEME software. command: meme -oc ../result/final_prediction/K562/inference_raw/MEME/RankLinear0.6_40_TEAD4/ -dna -nmotifs 5 -w 8 -maxsize 250000 -nostatus ../result/final_prediction/K562/fasta/RankLinear0.6_40/TEAD4.fasta model: mod= zoops nmotifs= 5 evt= inf objective function: em= E-value of product of p-values starts= E-value of product of p-values strands: + width: minw= 8 maxw= 8 nsites: minsites= 2 maxsites= 250 wnsites= 0.8 theta: spmap= uni spfuzz= 0.5 em: prior= dirichlet b= 0.01 maxiter= 50 distance= 1e-05 trim: wg= 11 ws= 1 endgaps= yes data: n= 20000 N= 250 sample: seed= 0 hsfrac= 0 searchsize= 20000 norand= no csites= 1000 Letter frequencies in dataset: A 0.273 C 0.223 G 0.238 T 0.265 Background letter frequencies (from file dataset with add-one prior applied): A 0.273 C 0.223 G 0.239 T 0.265 Background model order: 0 ******************************************************************************** ******************************************************************************** MOTIF AGATAAGR MEME-1 width = 8 sites = 134 llr = 932 E-value = 2.1e-059 ******************************************************************************** -------------------------------------------------------------------------------- Motif AGATAAGR MEME-1 Description -------------------------------------------------------------------------------- Simplified A 7:a:9924 pos.-specific C ::::::21 probability G :a:::163 matrix T 3::a1:11 bits 2.2 * 1.9 *** 1.7 *** 1.5 **** Relative 1.3 ***** Entropy 1.1 ***** (10.0 bits) 0.9 ***** 0.6 ****** 0.4 ******* 0.2 ******** 0.0 -------- Multilevel AGATAAGA consensus T AG sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AGATAAGR MEME-1 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr5:148127233-148127313 24 2.30e-05 atgtgttgga agataaga catgttcata chr3:71257577-71257657 19 2.30e-05 TCCAAGCAAA AGATAAGA AAAGCAAACC chr7:135718340-135718420 69 2.30e-05 TGTTCTTTCA AGATAAGA CAGC chr11:108094347-10809442 71 2.30e-05 TACCAGGTAC AGATAAGA CA chr15:35459071-35459151 44 2.30e-05 AGCTTAAGAG AGATAAGA CATGACTTTG chr16:55469427-55469507 51 2.30e-05 TGCCTACAGG AGATAAGA GGCTGGTGTG chr9:90419029-90419109 47 2.30e-05 TGGGAAGGCC AGATAAGA GCGCTGAGAG chr6:32256394-32256474 25 2.30e-05 GGATGATGAT AGATAAGA GTGTCTTTAT chr14:55850704-55850784 61 2.30e-05 TGCCTGCCAC AGATAAGA CTGTGGCCAG chr9:114856005-114856085 20 2.30e-05 TTGAGTATAA AGATAAGA GCTGCCACAG chr14:31291369-31291449 29 2.30e-05 ctgttcccag agataaga ttccctagcc chr12:21966225-21966305 52 2.30e-05 TTGCCCTGTG AGATAAGA TGTCAGGCTC chr5:131987918-131987998 56 2.30e-05 tgggaggcca agataaga ggatcacttg chr12:60538339-60538419 48 2.30e-05 tggctcagcg agataaga aataagggga chrX:107463299-107463379 10 4.30e-05 tgcttctac agataagg tcccctagcc chr6:123033599-123033679 40 4.30e-05 GGAGAGAGGT AGATAAGG CATTTGGTTA chr3:98302731-98302811 16 4.30e-05 TAAGGACCAG AGATAAGG GAGGCAGAAA chr20:42639110-42639190 38 4.30e-05 TGGGAAAACC AGATAAGG AGATGTACAT chr20:20927143-20927223 25 4.30e-05 TGTTTAAAGG AGATAAGG TGGGGGCTCA chr15:84131789-84131869 71 4.30e-05 tgcatatccg agataagg ct chr7:104607697-104607777 17 4.30e-05 TGGGCTGAGT AGATAAGG CAAGCTGGGA chr10:14223352-14223432 58 4.30e-05 CTGGGAGCCC AGATAAGG AGAAAGCTGA chr7:10747317-10747397 27 4.30e-05 caggctagag agataagg ccttctggta chr1:179941155-179941235 44 4.30e-05 TGGATGACTG AGATAAGG AATACCTCGT chr15:31270673-31270753 38 4.30e-05 GCTGGCTGGA AGATAAGG GCTGTTTGGG chr1:206909005-206909085 55 8.41e-05 ccagctggtg tgataaga ttgagcccac chr15:39432297-39432377 21 8.41e-05 CGCCCTGCAG TGATAAGA GCACAGCTGT chr4:155377536-155377616 39 8.41e-05 ccaacggaga agataagc acacagagag chr10:121904786-12190486 37 8.41e-05 TGCAAATCAA TGATAAGA AAAGCTGTGC chr1:45501483-45501563 21 8.41e-05 TCCTGGAGGA AGATAAGC CAGCCAGTTA chrX:47676964-47677044 48 8.41e-05 AGTTAGGGCC AGATAAGC CTAACTGCAA chr1:213779222-213779302 60 8.41e-05 gtgcaaacca tgataaga aaagcccaag chr1:109677204-109677284 15 8.41e-05 GTTGGCCTAC TGATAAGA AACCGTGGCT chr6:140069947-140070027 60 8.41e-05 GCAAGGACAC AGATAAGC AAAGTGTTGC chr2:15696580-15696660 61 8.41e-05 TGGACATTCA AGATAAGC CTGAGAATAG chr2:42423647-42423727 34 8.41e-05 TGTGAGACTA TGATAAGA GTTCCGTCTG chr8:21366961-21367041 33 8.41e-05 tgtggaacag agataagc catccaagct chrX:107801631-107801711 22 8.41e-05 GTAAAGGTGC TGATAAGA TATGATGGGT chr17:33212288-33212368 61 8.41e-05 TGCTTCTTGG AGATAAGC TCCCAATAGT chr8:23526275-23526355 23 8.41e-05 TGGTGGTTGG AGATAAGC TTATCTGGTT chr4:20700585-20700665 20 1.04e-04 gactcatagc tgataagg ggtggtgagt chr19:14253631-14253711 24 1.04e-04 acagctgtgc tgataagg taaccactag chr8:86290464-86290544 62 1.04e-04 tgtgagaacc tgataagg gaagtggttg chr6:20575569-20575649 69 1.04e-04 CTTGTCAGTG TGATAAGG GATA chr8:67967436-67967516 61 1.04e-04 gtgcagtctg tgataagg actaaggatc chrX:119468577-119468657 20 1.04e-04 ctgctcctac tgataagg tcccctagcc chr2:58349849-58349929 72 1.74e-04 GTGTGAATAC AGATAAAA A chr7:44120948-44121028 5 1.74e-04 gcag agataaca tatccaccct chr7:39849958-39850038 28 1.74e-04 CACATGGGCC AGATAACA CAGCACAGCT chr3:179093055-179093135 66 1.74e-04 TGGCAGCTGA AGATAAAA GGTATGA chr4:109035778-109035858 42 1.74e-04 ATGTCTGAGG AGATAACA CGAAAATACT chr3:105333306-105333386 67 1.74e-04 GCTTGGAAAG AGATAACA TGTTTC chr16:22227757-22227837 22 1.74e-04 GTTGATAAGC AGATAAGT AGCTCTTCTG chrX:99998389-99998469 45 1.74e-04 GGAGTCATAA AGATAAAA TTCTTGTGGG chrX:10127231-10127311 23 1.74e-04 CAGCTTCCAA AGATAACA TGTGAGCGTA chr1:246588580-246588660 53 1.74e-04 ACACCAACCT AGATAACA AAGACCACAG chr1:209819337-209819417 15 1.74e-04 TGtttccaag agataaaa atgacagctg chr7:119566125-119566205 41 1.74e-04 GCTGTTTATG AGATAAAA GCACAGTTGT chr7:37397333-37397413 42 1.74e-04 GTTTGGTTTA AGATAAAA CACAGTCAGG chr4:95574450-95574530 48 1.74e-04 tggacaaatt agataagt gtaaaagtgc chr1:45362178-45362258 59 1.74e-04 CTGTTCACCT AGATAAGT TTCCGCCTTG chr4:25052511-25052591 30 1.74e-04 TGTTAGGGTC AGATAAGT CCTGGTTAGG chr3:137918873-137918953 72 1.74e-04 tggcattcat agataagt t chr6:152554103-152554183 58 1.74e-04 agagagataa agataaaa tgttctggga chr5:148126515-148126595 71 2.15e-04 AAAGAGATTT AGATAAAG CT chr9:127727085-127727165 71 2.15e-04 gcagctttat agataaag ac chr4:122715802-122715882 30 2.15e-04 tgtaaaagac agataaCG AATACTggtt chr1:214593156-214593236 29 2.15e-04 CTGTAAATCC AGATAAAG GACAGGGTGG chr10:82531902-82531982 70 2.15e-04 tGAGTGGTGG AGATAAAG ACA chr9:7067327-7067407 2 2.15e-04 T AGATAAAG CACAACAGTT chrX:55054603-55054683 30 2.15e-04 TGCAGACCAC AGATAAAG TTGCCAGAGT chr10:63540244-63540324 30 2.15e-04 GGCCTCCACT AGATAAAG ACATCTGGAT chr8:96939401-96939481 36 2.33e-04 TTTTATGGAC TGATAAGC TAAGTTAGCA chr8:106532850-106532930 20 2.33e-04 TGGTTGATTG TGATAAGC ATTGTCGTAG chrX:55041562-55041642 64 2.54e-04 TGCTGCTTTG AGATAGGA CTTTCAAGT chr16:25783255-25783335 25 2.54e-04 ATTTAGTGGA AGATAGGA TAACGTTTCT chr8:2645835-2645915 60 2.54e-04 ccagctctgg agatagga agacaggttc chr2:84198848-84198928 17 3.78e-04 TGGAAGACAG AGATAACC AAGGCAATTT chr7:116079238-116079318 22 3.78e-04 GCTGACACTG TGATAAGT GTTATCATAC chr3:154736918-154736998 70 3.78e-04 CTGTTAGAGC AGATAACC TTG chr6:126439349-126439429 67 3.78e-04 TCTCGGAAAA TGATAACA CTCTAA chr5:29796337-29796417 43 3.78e-04 AGTTGAATAA AGATAACC TGGACCACCA chr1:206266182-206266262 19 3.78e-04 tccgtgctat agataaac atgaatgctt chr15:50886658-50886738 43 3.78e-04 TGGCTAAGAA TGATAAGT GGAGGAGGCA chr20:5469588-5469668 27 3.78e-04 tgcttccaga agataggg gctgtggtga chr1:70005901-70005981 43 3.78e-04 GTGAGGACTA AGATAGGG TCGAGTTATC chrX:39011780-39011860 41 3.78e-04 ATGCTTGTCC TGATAAAA TAATTACCCA chr7:24903968-24904048 71 3.78e-04 tgtgcattgc tgataagt tc chr15:57675325-57675405 70 4.18e-04 GGAGAGGACC TGATAAAG AAT chr7:66387286-66387366 4 4.18e-04 ATG TGATAAAG TGGTTTGTCT chr8:87522864-87522944 50 4.90e-04 aagctatgac agataata aatgattgtt chr6:80314395-80314475 28 4.90e-04 tgttgggggc agataact tgtcttttta chr4:10347164-10347244 32 4.90e-04 TACAACGGAC AGATAATA AAATACCTTA chr6:74238821-74238901 62 4.90e-04 tgtaaaaagg agataata ataactattc chr2:30476952-30477032 63 4.90e-04 ctgaaaccac agataata ccaaacccac chr15:92021984-92022064 55 5.53e-04 TGTACTATAG CGATAAGA CGCCATGGGG chr10:17045278-17045358 62 5.53e-04 TCTGCGCCTG AGATTAGA ACCAGACAGT chr1:222883255-222883335 68 5.53e-04 TGTTGTATGG CGATAAGA TTGCT chr13:99628332-99628412 34 5.53e-04 AAACACTGCC CGATAAGA AAAAACTTCT chr4:103277024-103277104 51 5.53e-04 CTGGAGAGTA AGATTAGA AAAATGGGAC chr6:19968588-19968668 68 5.89e-04 tggtagatct agataggc tcact chr9:101553585-101553665 1 5.89e-04 . AGATAGGC TGGGCATTGC chr14:75177348-75177428 15 6.25e-04 TGCTCCAGAA AGATTAGG AACTTCTAGT chr4:151695355-151695435 49 6.25e-04 tgactatgaa agattagg ccttcaacat chr6:109606071-109606151 73 6.80e-04 TCTGGTCACC TGATAACC chr12:65114788-65114868 71 6.80e-04 GAGCATATGC TGATAAAC AG chr3:42391380-42391460 40 7.41e-04 GTAAGGCTGA AGATAGAA GCCCCACCCT chr2:145978784-145978864 5 7.41e-04 TTAA AGATAGAA CTGATATTAG chrX:109202815-109202895 35 7.41e-04 tgtaaaaggg agatagca gtgtagtact chr13:44961220-44961300 73 7.41e-04 ACTGTCACAC AGATAGGT chr8:131355454-131355534 43 8.88e-04 TGTATGGGGC AGATAGAG AAGTCACTAC chr3:142337811-142337891 43 8.88e-04 TTGACAAATA AGATAGCG GTGGTTATCG chr1:168257599-168257679 27 8.88e-04 tgactgTACA TGATAACT ATTATCATTA chr6:164767864-164767944 34 8.88e-04 CTGCATCCTT GGATAAGA CAGATGGAAG chrX:134996735-134996815 2 8.88e-04 c tgataact ctgcaggcag chr19:16308205-16308285 52 8.88e-04 actcattcat tgataaat gttgacaatg chr1:230341606-230341686 54 8.88e-04 cccggaatgt tgataact tgcccagtga chr1:26087554-26087634 60 8.88e-04 tgttacactg agataatc ccttgtcggt chr1:206274318-206274398 45 8.88e-04 cgtcctgtcc tgataact gaccaccaac chr5:89940129-89940209 35 9.83e-04 GTGTCTGTCT GGATAAGG AAATCACACT chr7:102082193-102082273 72 9.83e-04 TGCACCTGCT TGATTAGA T chr2:32993554-32993634 65 9.83e-04 TGCCAGGAAA TGATAATG GACAGAAC chr6:119863407-119863487 49 9.83e-04 TGCTGTTGTC TGATAATG GTTATCGCTG chr4:79405857-79405937 64 9.83e-04 tctatttagt ggataagg aaactgaga chr20:37192564-37192644 25 9.83e-04 tgaagaggag agaTTAGC CAGATCTCAG chr5:178110934-178111014 38 1.17e-03 ttttctgtga cgataaaa acattttgta chr5:95220353-95220433 7 1.17e-03 TTGAAA AGATTAGT CTTATCCTAT chr16:66651869-66651949 7 1.26e-03 TAGTGC TGATAGCA GACAGGTGGG chr16:8688297-8688377 28 1.34e-03 ACGGCATTTA AGATTAAG GCTACACCAG chr16:50105138-50105218 65 1.34e-03 TTAGAATACA AGATTAAG TTGGATCC chr4:160116714-160116794 5 1.34e-03 gaga cgataaag aactgccaag chr13:39573051-39573131 28 1.41e-03 atgtggggca tgatagag agcctgcctt chr12:28345227-28345307 35 1.47e-03 TTATGAATGA AGATAGTA GAAGACGGAG chr2:46666870-46666950 26 1.47e-03 CAGTGGGACA AGATAGCT CTTGCACCTG -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AGATAAGR MEME-1 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr5:148127233-148127313 2.3e-05 23_[+1]_49 chr3:71257577-71257657 2.3e-05 18_[+1]_54 chr7:135718340-135718420 2.3e-05 68_[+1]_4 chr11:108094347-10809442 2.3e-05 70_[+1]_2 chr15:35459071-35459151 2.3e-05 43_[+1]_29 chr16:55469427-55469507 2.3e-05 50_[+1]_22 chr9:90419029-90419109 2.3e-05 46_[+1]_26 chr6:32256394-32256474 2.3e-05 24_[+1]_48 chr14:55850704-55850784 2.3e-05 60_[+1]_12 chr9:114856005-114856085 2.3e-05 19_[+1]_53 chr14:31291369-31291449 2.3e-05 28_[+1]_44 chr12:21966225-21966305 2.3e-05 51_[+1]_21 chr5:131987918-131987998 2.3e-05 55_[+1]_17 chr12:60538339-60538419 2.3e-05 47_[+1]_25 chrX:107463299-107463379 4.3e-05 9_[+1]_63 chr6:123033599-123033679 4.3e-05 39_[+1]_33 chr3:98302731-98302811 4.3e-05 15_[+1]_57 chr20:42639110-42639190 4.3e-05 37_[+1]_35 chr20:20927143-20927223 4.3e-05 24_[+1]_48 chr15:84131789-84131869 4.3e-05 70_[+1]_2 chr7:104607697-104607777 4.3e-05 16_[+1]_56 chr10:14223352-14223432 4.3e-05 57_[+1]_15 chr7:10747317-10747397 4.3e-05 26_[+1]_46 chr1:179941155-179941235 4.3e-05 43_[+1]_29 chr15:31270673-31270753 4.3e-05 37_[+1]_35 chr1:206909005-206909085 8.4e-05 54_[+1]_18 chr15:39432297-39432377 8.4e-05 20_[+1]_52 chr4:155377536-155377616 8.4e-05 38_[+1]_34 chr10:121904786-12190486 8.4e-05 36_[+1]_36 chr1:45501483-45501563 8.4e-05 20_[+1]_52 chrX:47676964-47677044 8.4e-05 47_[+1]_25 chr1:213779222-213779302 8.4e-05 59_[+1]_13 chr1:109677204-109677284 8.4e-05 14_[+1]_58 chr6:140069947-140070027 8.4e-05 59_[+1]_13 chr2:15696580-15696660 8.4e-05 60_[+1]_12 chr2:42423647-42423727 8.4e-05 33_[+1]_39 chr8:21366961-21367041 8.4e-05 32_[+1]_40 chrX:107801631-107801711 8.4e-05 21_[+1]_51 chr17:33212288-33212368 8.4e-05 60_[+1]_12 chr8:23526275-23526355 8.4e-05 22_[+1]_50 chr4:20700585-20700665 0.0001 19_[+1]_53 chr19:14253631-14253711 0.0001 23_[+1]_49 chr8:86290464-86290544 0.0001 61_[+1]_11 chr6:20575569-20575649 0.0001 68_[+1]_4 chr8:67967436-67967516 0.0001 60_[+1]_12 chrX:119468577-119468657 0.0001 19_[+1]_53 chr2:58349849-58349929 0.00017 71_[+1]_1 chr7:44120948-44121028 0.00017 4_[+1]_68 chr7:39849958-39850038 0.00017 27_[+1]_45 chr3:179093055-179093135 0.00017 65_[+1]_7 chr4:109035778-109035858 0.00017 41_[+1]_31 chr3:105333306-105333386 0.00017 66_[+1]_6 chr16:22227757-22227837 0.00017 21_[+1]_51 chrX:99998389-99998469 0.00017 44_[+1]_28 chrX:10127231-10127311 0.00017 22_[+1]_50 chr1:246588580-246588660 0.00017 52_[+1]_20 chr1:209819337-209819417 0.00017 14_[+1]_58 chr7:119566125-119566205 0.00017 40_[+1]_32 chr7:37397333-37397413 0.00017 41_[+1]_31 chr4:95574450-95574530 0.00017 47_[+1]_25 chr1:45362178-45362258 0.00017 58_[+1]_14 chr4:25052511-25052591 0.00017 29_[+1]_43 chr3:137918873-137918953 0.00017 71_[+1]_1 chr6:152554103-152554183 0.00017 57_[+1]_15 chr5:148126515-148126595 0.00022 70_[+1]_2 chr9:127727085-127727165 0.00022 70_[+1]_2 chr4:122715802-122715882 0.00022 29_[+1]_43 chr1:214593156-214593236 0.00022 28_[+1]_44 chr10:82531902-82531982 0.00022 69_[+1]_3 chr9:7067327-7067407 0.00022 1_[+1]_71 chrX:55054603-55054683 0.00022 29_[+1]_43 chr10:63540244-63540324 0.00022 29_[+1]_43 chr8:96939401-96939481 0.00023 35_[+1]_37 chr8:106532850-106532930 0.00023 19_[+1]_53 chrX:55041562-55041642 0.00025 63_[+1]_9 chr16:25783255-25783335 0.00025 24_[+1]_48 chr8:2645835-2645915 0.00025 59_[+1]_13 chr2:84198848-84198928 0.00038 16_[+1]_56 chr7:116079238-116079318 0.00038 21_[+1]_51 chr3:154736918-154736998 0.00038 69_[+1]_3 chr6:126439349-126439429 0.00038 66_[+1]_6 chr5:29796337-29796417 0.00038 42_[+1]_30 chr1:206266182-206266262 0.00038 18_[+1]_54 chr15:50886658-50886738 0.00038 42_[+1]_30 chr20:5469588-5469668 0.00038 26_[+1]_46 chr1:70005901-70005981 0.00038 42_[+1]_30 chrX:39011780-39011860 0.00038 40_[+1]_32 chr7:24903968-24904048 0.00038 70_[+1]_2 chr15:57675325-57675405 0.00042 69_[+1]_3 chr7:66387286-66387366 0.00042 3_[+1]_69 chr8:87522864-87522944 0.00049 49_[+1]_23 chr6:80314395-80314475 0.00049 27_[+1]_45 chr4:10347164-10347244 0.00049 31_[+1]_41 chr6:74238821-74238901 0.00049 61_[+1]_11 chr2:30476952-30477032 0.00049 62_[+1]_10 chr15:92021984-92022064 0.00055 54_[+1]_18 chr10:17045278-17045358 0.00055 61_[+1]_11 chr1:222883255-222883335 0.00055 67_[+1]_5 chr13:99628332-99628412 0.00055 33_[+1]_39 chr4:103277024-103277104 0.00055 50_[+1]_22 chr6:19968588-19968668 0.00059 67_[+1]_5 chr9:101553585-101553665 0.00059 [+1]_72 chr14:75177348-75177428 0.00063 14_[+1]_58 chr4:151695355-151695435 0.00063 48_[+1]_24 chr6:109606071-109606151 0.00068 72_[+1] chr12:65114788-65114868 0.00068 70_[+1]_2 chr3:42391380-42391460 0.00074 39_[+1]_33 chr2:145978784-145978864 0.00074 4_[+1]_68 chrX:109202815-109202895 0.00074 34_[+1]_38 chr13:44961220-44961300 0.00074 72_[+1] chr8:131355454-131355534 0.00089 42_[+1]_30 chr3:142337811-142337891 0.00089 42_[+1]_30 chr1:168257599-168257679 0.00089 26_[+1]_46 chr6:164767864-164767944 0.00089 33_[+1]_39 chrX:134996735-134996815 0.00089 1_[+1]_71 chr19:16308205-16308285 0.00089 51_[+1]_21 chr1:230341606-230341686 0.00089 53_[+1]_19 chr1:26087554-26087634 0.00089 59_[+1]_13 chr1:206274318-206274398 0.00089 44_[+1]_28 chr5:89940129-89940209 0.00098 34_[+1]_38 chr7:102082193-102082273 0.00098 71_[+1]_1 chr2:32993554-32993634 0.00098 64_[+1]_8 chr6:119863407-119863487 0.00098 48_[+1]_24 chr4:79405857-79405937 0.00098 63_[+1]_9 chr20:37192564-37192644 0.00098 24_[+1]_48 chr5:178110934-178111014 0.0012 37_[+1]_35 chr5:95220353-95220433 0.0012 6_[+1]_66 chr16:66651869-66651949 0.0013 6_[+1]_66 chr16:8688297-8688377 0.0013 27_[+1]_45 chr16:50105138-50105218 0.0013 64_[+1]_8 chr4:160116714-160116794 0.0013 4_[+1]_68 chr13:39573051-39573131 0.0014 27_[+1]_45 chr12:28345227-28345307 0.0015 34_[+1]_38 chr2:46666870-46666950 0.0015 25_[+1]_47 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AGATAAGR MEME-1 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF AGATAAGR width=8 seqs=134 chr5:148127233-148127313 ( 24) AGATAAGA 1 chr3:71257577-71257657 ( 19) AGATAAGA 1 chr7:135718340-135718420 ( 69) AGATAAGA 1 chr11:108094347-10809442 ( 71) AGATAAGA 1 chr15:35459071-35459151 ( 44) AGATAAGA 1 chr16:55469427-55469507 ( 51) AGATAAGA 1 chr9:90419029-90419109 ( 47) AGATAAGA 1 chr6:32256394-32256474 ( 25) AGATAAGA 1 chr14:55850704-55850784 ( 61) AGATAAGA 1 chr9:114856005-114856085 ( 20) AGATAAGA 1 chr14:31291369-31291449 ( 29) AGATAAGA 1 chr12:21966225-21966305 ( 52) AGATAAGA 1 chr5:131987918-131987998 ( 56) AGATAAGA 1 chr12:60538339-60538419 ( 48) AGATAAGA 1 chrX:107463299-107463379 ( 10) AGATAAGG 1 chr6:123033599-123033679 ( 40) AGATAAGG 1 chr3:98302731-98302811 ( 16) AGATAAGG 1 chr20:42639110-42639190 ( 38) AGATAAGG 1 chr20:20927143-20927223 ( 25) AGATAAGG 1 chr15:84131789-84131869 ( 71) AGATAAGG 1 chr7:104607697-104607777 ( 17) AGATAAGG 1 chr10:14223352-14223432 ( 58) AGATAAGG 1 chr7:10747317-10747397 ( 27) AGATAAGG 1 chr1:179941155-179941235 ( 44) AGATAAGG 1 chr15:31270673-31270753 ( 38) AGATAAGG 1 chr1:206909005-206909085 ( 55) TGATAAGA 1 chr15:39432297-39432377 ( 21) TGATAAGA 1 chr4:155377536-155377616 ( 39) AGATAAGC 1 chr10:121904786-12190486 ( 37) TGATAAGA 1 chr1:45501483-45501563 ( 21) AGATAAGC 1 chrX:47676964-47677044 ( 48) AGATAAGC 1 chr1:213779222-213779302 ( 60) TGATAAGA 1 chr1:109677204-109677284 ( 15) TGATAAGA 1 chr6:140069947-140070027 ( 60) AGATAAGC 1 chr2:15696580-15696660 ( 61) AGATAAGC 1 chr2:42423647-42423727 ( 34) TGATAAGA 1 chr8:21366961-21367041 ( 33) AGATAAGC 1 chrX:107801631-107801711 ( 22) TGATAAGA 1 chr17:33212288-33212368 ( 61) AGATAAGC 1 chr8:23526275-23526355 ( 23) AGATAAGC 1 chr4:20700585-20700665 ( 20) TGATAAGG 1 chr19:14253631-14253711 ( 24) TGATAAGG 1 chr8:86290464-86290544 ( 62) TGATAAGG 1 chr6:20575569-20575649 ( 69) TGATAAGG 1 chr8:67967436-67967516 ( 61) TGATAAGG 1 chrX:119468577-119468657 ( 20) TGATAAGG 1 chr2:58349849-58349929 ( 72) AGATAAAA 1 chr7:44120948-44121028 ( 5) AGATAACA 1 chr7:39849958-39850038 ( 28) AGATAACA 1 chr3:179093055-179093135 ( 66) AGATAAAA 1 chr4:109035778-109035858 ( 42) AGATAACA 1 chr3:105333306-105333386 ( 67) AGATAACA 1 chr16:22227757-22227837 ( 22) AGATAAGT 1 chrX:99998389-99998469 ( 45) AGATAAAA 1 chrX:10127231-10127311 ( 23) AGATAACA 1 chr1:246588580-246588660 ( 53) AGATAACA 1 chr1:209819337-209819417 ( 15) AGATAAAA 1 chr7:119566125-119566205 ( 41) AGATAAAA 1 chr7:37397333-37397413 ( 42) AGATAAAA 1 chr4:95574450-95574530 ( 48) AGATAAGT 1 chr1:45362178-45362258 ( 59) AGATAAGT 1 chr4:25052511-25052591 ( 30) AGATAAGT 1 chr3:137918873-137918953 ( 72) AGATAAGT 1 chr6:152554103-152554183 ( 58) AGATAAAA 1 chr5:148126515-148126595 ( 71) AGATAAAG 1 chr9:127727085-127727165 ( 71) AGATAAAG 1 chr4:122715802-122715882 ( 30) AGATAACG 1 chr1:214593156-214593236 ( 29) AGATAAAG 1 chr10:82531902-82531982 ( 70) AGATAAAG 1 chr9:7067327-7067407 ( 2) AGATAAAG 1 chrX:55054603-55054683 ( 30) AGATAAAG 1 chr10:63540244-63540324 ( 30) AGATAAAG 1 chr8:96939401-96939481 ( 36) TGATAAGC 1 chr8:106532850-106532930 ( 20) TGATAAGC 1 chrX:55041562-55041642 ( 64) AGATAGGA 1 chr16:25783255-25783335 ( 25) AGATAGGA 1 chr8:2645835-2645915 ( 60) AGATAGGA 1 chr2:84198848-84198928 ( 17) AGATAACC 1 chr7:116079238-116079318 ( 22) TGATAAGT 1 chr3:154736918-154736998 ( 70) AGATAACC 1 chr6:126439349-126439429 ( 67) TGATAACA 1 chr5:29796337-29796417 ( 43) AGATAACC 1 chr1:206266182-206266262 ( 19) AGATAAAC 1 chr15:50886658-50886738 ( 43) TGATAAGT 1 chr20:5469588-5469668 ( 27) AGATAGGG 1 chr1:70005901-70005981 ( 43) AGATAGGG 1 chrX:39011780-39011860 ( 41) TGATAAAA 1 chr7:24903968-24904048 ( 71) TGATAAGT 1 chr15:57675325-57675405 ( 70) TGATAAAG 1 chr7:66387286-66387366 ( 4) TGATAAAG 1 chr8:87522864-87522944 ( 50) AGATAATA 1 chr6:80314395-80314475 ( 28) AGATAACT 1 chr4:10347164-10347244 ( 32) AGATAATA 1 chr6:74238821-74238901 ( 62) AGATAATA 1 chr2:30476952-30477032 ( 63) AGATAATA 1 chr15:92021984-92022064 ( 55) CGATAAGA 1 chr10:17045278-17045358 ( 62) AGATTAGA 1 chr1:222883255-222883335 ( 68) CGATAAGA 1 chr13:99628332-99628412 ( 34) CGATAAGA 1 chr4:103277024-103277104 ( 51) AGATTAGA 1 chr6:19968588-19968668 ( 68) AGATAGGC 1 chr9:101553585-101553665 ( 1) AGATAGGC 1 chr14:75177348-75177428 ( 15) AGATTAGG 1 chr4:151695355-151695435 ( 49) AGATTAGG 1 chr6:109606071-109606151 ( 73) TGATAACC 1 chr12:65114788-65114868 ( 71) TGATAAAC 1 chr3:42391380-42391460 ( 40) AGATAGAA 1 chr2:145978784-145978864 ( 5) AGATAGAA 1 chrX:109202815-109202895 ( 35) AGATAGCA 1 chr13:44961220-44961300 ( 73) AGATAGGT 1 chr8:131355454-131355534 ( 43) AGATAGAG 1 chr3:142337811-142337891 ( 43) AGATAGCG 1 chr1:168257599-168257679 ( 27) TGATAACT 1 chr6:164767864-164767944 ( 34) GGATAAGA 1 chrX:134996735-134996815 ( 2) TGATAACT 1 chr19:16308205-16308285 ( 52) TGATAAAT 1 chr1:230341606-230341686 ( 54) TGATAACT 1 chr1:26087554-26087634 ( 60) AGATAATC 1 chr1:206274318-206274398 ( 45) TGATAACT 1 chr5:89940129-89940209 ( 35) GGATAAGG 1 chr7:102082193-102082273 ( 72) TGATTAGA 1 chr2:32993554-32993634 ( 65) TGATAATG 1 chr6:119863407-119863487 ( 49) TGATAATG 1 chr4:79405857-79405937 ( 64) GGATAAGG 1 chr20:37192564-37192644 ( 25) AGATTAGC 1 chr5:178110934-178111014 ( 38) CGATAAAA 1 chr5:95220353-95220433 ( 7) AGATTAGT 1 chr16:66651869-66651949 ( 7) TGATAGCA 1 chr16:8688297-8688377 ( 28) AGATTAAG 1 chr16:50105138-50105218 ( 65) AGATTAAG 1 chr4:160116714-160116794 ( 5) CGATAAAG 1 chr13:39573051-39573131 ( 28) TGATAGAG 1 chr12:28345227-28345307 ( 35) AGATAGTA 1 chr2:46666870-46666950 ( 26) AGATAGCT 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AGATAAGR MEME-1 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 8.84505 E= 2.1e-059 133 -258 -341 -6 -1371 -1371 207 -1371 187 -1371 -1371 -1371 -1371 -1371 -1371 192 177 -1371 -1371 -198 168 -1371 -91 -1371 -39 -51 127 -215 61 -58 36 -106 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AGATAAGR MEME-1 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 134 E= 2.1e-059 0.686567 0.037313 0.022388 0.253731 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.932836 0.000000 0.000000 0.067164 0.873134 0.000000 0.126866 0.000000 0.208955 0.156716 0.574627 0.059701 0.417910 0.149254 0.305970 0.126866 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AGATAAGR MEME-1 regular expression -------------------------------------------------------------------------------- [AT]GATAA[GA][AG] -------------------------------------------------------------------------------- Time 5.02 secs. ******************************************************************************** ******************************************************************************** MOTIF BCTTATCW MEME-2 width = 8 sites = 86 llr = 627 E-value = 8.5e-025 ******************************************************************************** -------------------------------------------------------------------------------- Motif BCTTATCW MEME-2 Description -------------------------------------------------------------------------------- Simplified A 21:1a::4 pos.-specific C 25::::a: probability G 32:::::: matrix T 42a9:a:6 bits 2.2 * 1.9 * *** 1.7 * *** 1.5 * *** Relative 1.3 ***** Entropy 1.1 ***** (10.5 bits) 0.9 ****** 0.6 ****** 0.4 ****** 0.2 ******* 0.0 -------- Multilevel TCTTATCT consensus GG A sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif BCTTATCW MEME-2 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr6:108880388-108880468 72 1.77e-05 GCGGCCAGCA TCTTATCT C chrX:130086522-130086602 71 1.77e-05 ctgtggtttg tcttatct ct chr10:62022655-62022735 58 1.77e-05 ACTACTGCTA TCTTATCT GGCACATGCT chr6:4177221-4177301 73 1.77e-05 ataACCTCTT TCTTATCT chr1:48643126-48643206 40 1.77e-05 acaagatttt tcttatct atggccggca chr9:131355491-131355571 18 3.37e-05 GTCGATGACT GCTTATCT CATTGGTTGC chr7:115858315-115858395 18 3.37e-05 TCATTGCATA GCTTATCT GAGCAGCGAG chr16:81254217-81254297 24 3.37e-05 TCACCTGTCT GCTTATCT TTCAGTCAAC chr3:42391380-42391460 3 3.37e-05 AG GCTTATCT TCAGGCCTCA chr17:57762504-57762584 12 3.37e-05 GAGAATTGCT GCTTATCT CTTCAAAGGC chr22:30348257-30348337 7 3.37e-05 TTAGCA GCTTATCT GTGCCCCACA chr4:99603973-99604053 25 3.37e-05 tgcagacctt gcttatct ctctccccac chr1:230341606-230341686 10 3.37e-05 aggcttgaa gcttatct tcatacacag chr11:67116039-67116119 53 6.70e-05 gccttggttt ccttatct gtaaaacatg chr6:159920213-159920293 19 6.70e-05 tccatttcac ccttatct atagggtgca chr12:92798843-92798923 30 6.70e-05 GCTTCTTCTG CCTTATCT TTGGTCTCCT chr1:206266182-206266262 45 6.70e-05 ttcctctttt tcttatca ctgttaccca chr16:66651869-66651949 48 6.70e-05 CTGCTTCCTC CCTTATCT CCCAGACCTG chr1:101251443-101251523 25 6.70e-05 gttggcggtc tcttatca ggaaggaatg chr4:10347164-10347244 45 6.70e-05 TAATAAAATA CCTTATCT ATTCAGTCAC chr4:79405857-79405937 12 6.70e-05 atccattaag ccttatct cacttgctca chr7:148545022-148545102 26 6.70e-05 AATTCTTCTG CCTTATCT TTAGTTGCAG chrX:39011780-39011860 15 6.70e-05 GCTGTTTTTC TCTTATCA TGACAGAAAT chr1:51186307-51186387 60 6.70e-05 accctaggaa tcttatca accagggaaa chr1:214176684-214176764 10 6.70e-05 GCCTAAAAC TCTTATCA CAAGGCAGTC chr4:96210548-96210628 1 8.60e-05 . TGTTATCT GCTGCTGGCC chr3:170079718-170079798 47 8.60e-05 TGCGCTTTGG TGTTATCT CCATTTGCAA chr3:32750308-32750388 8 8.60e-05 TTTGGTA TGTTATCT GTCAAGTCAA chr3:133472769-133472849 11 1.02e-04 AGGGGCATAT GCTTATCA GAGAAACACA chr21:32754500-32754580 52 1.02e-04 ATGTTTGAAC GCTTATCA GCGCACTGTA chrX:107463299-107463379 38 1.36e-04 gaacaactct ccttatca aatggaccag chr5:89954577-89954657 41 1.36e-04 GTCTTACTGT CCTTATCA GTTCTTTCCA chrX:119468577-119468657 48 1.36e-04 aaaaagctct ccttatca cagggatcag chr2:84198848-84198928 32 1.57e-04 ACCAAGGCAA TTTTATCT GGGCCAGACA chrX:40403744-40403824 3 1.57e-04 AG TTTTATCT GAAAAACCAG chr11:422363-422443 9 1.57e-04 caaaggaa ttttatct cacaaggcag chr9:125016706-125016786 50 1.57e-04 CTGCAAGCAC TTTTATCT GCTGCTGAAG chrX:49963276-49963356 21 1.57e-04 ATGAGTCATT TTTTATCT TACCACTTTC chr3:151444006-151444086 64 1.74e-04 cttggttcga ggttatct aatttttag chr7:5123117-5123197 17 1.74e-04 CATCCGGCAT GGTTATCT GCGCTTGCAA chrX:45024397-45024477 3 2.10e-04 CT TGTTATCA GCCAAGCCTA chr10:96059329-96059409 26 2.10e-04 GGCAGGCAGC TGTTATCA TTCATCTCGC chr9:86958274-86958354 71 2.10e-04 tttcttttct TGTTATCA TG chr2:178504405-178504485 38 2.10e-04 GGTCCACATC TGTTATCA TCTGGCTCAG chr7:127627082-127627162 30 2.10e-04 TGCACTGGTA TGTTATCA GAAAAGACAG chr2:30476952-30477032 11 2.10e-04 cagtagtccc cgttatct ctgggggata chr3:154736918-154736998 49 2.32e-04 TCTGGGATGA TATTATCT AAACTGTTAG chr2:46666870-46666950 62 2.32e-04 TTTAGACACG TATTATCT TAACAGCCAG chr22:40725269-40725349 53 2.32e-04 GAAAACAGAA TATTATCT AGATTTCCAG chr9:127727085-127727165 34 2.69e-04 ggcagctggt gtttatct tttctgtcaa chr8:97656729-97656809 16 2.69e-04 AGGAATTTGC ACTTATCA AAACATAAAG chr16:22227757-22227837 43 2.69e-04 TCTTCTGCTT ACTTATCA CTCATTCACA chr18:67692991-67693071 9 2.69e-04 tccacata gtttatct gtattttcat chr2:68220641-68220721 43 2.69e-04 CTGCAGTAAC ACTTATCA CTAGTTATCA chr10:126406632-12640671 39 3.09e-04 GCAGTGATCT CTTTATCT AGGAGGCCTG chr4:81174848-81174928 6 3.09e-04 GCATG CTTTATCT TCTAGGGTCA chr17:33214019-33214099 56 3.09e-04 GGTGTAAAGC TTTTATCA GTATTGCCAA chr12:60538339-60538419 1 3.09e-04 . ttttatca tgatcagcat chr6:123033599-123033679 53 3.27e-04 TAAGGCATTT GGTTATCA GGGGAGACCA chr1:95100703-95100783 22 3.27e-04 GGGAGCAGCT GGTTATCA TGAACCATGT chr18:75034062-75034142 52 3.82e-04 atgacacagc cgttatca gaagtgaaCA chr1:204196621-204196701 53 3.82e-04 AGTTCCTCAT AGTTATCT TTTCTTAGCA chr7:134519773-134519853 25 4.41e-04 GGCCTCTGTA TCTAATCT ATGGGCTTGC chr22:40718275-40718355 33 4.41e-04 tagcctccac tattatca acatcctcca chr12:89787579-89787659 17 4.41e-04 AACACAGCTC TCTAATCT GTTGCAAAAT chr5:169514580-169514660 3 4.41e-04 ct cattatct ccttcctcca chr13:44972150-44972230 24 4.41e-04 TCCGATTAGT CATTATCT CCTCTGTGGT chr15:64731399-64731479 34 4.61e-04 AATGAGAACT GTTTATCA CAGAGCACAG chr1:45501483-45501563 38 5.01e-04 CCAGCCAGTT ATTTATCT GTATGCTTCC chr2:178939662-178939742 33 5.01e-04 CCACATTGCC ATTTATCT TCACTCTCAA chr7:104607697-104607777 47 5.58e-04 TGGTTCAGTT GATTATCA GTATCTTCAG chr2:145978784-145978864 43 5.58e-04 TTCTCTCCTT AGTTATCA TGAGTTCACA chr1:70005901-70005981 54 5.58e-04 GATAGGGTCG AGTTATCA GGGAAGACAA chr1:39210366-39210446 47 6.33e-04 gtggtttgta aattatct gtctgtggta chr8:23366395-23366475 65 6.33e-04 CCGCCCTCTC TCTAATCA ACCAGAAA chr2:74311079-74311159 38 6.33e-04 ATGCACTCAG CCTAATCT GCAGGAAGCC chr11:59735657-59735737 21 6.33e-04 GTTGGGTCAC AATTATCT CATGGTTACA chr8:56926571-56926651 6 6.33e-04 ATAAA Aattatct ctaactcaca chr6:21102063-21102143 22 6.33e-04 tgtactccta tctaatca gttaccaaga chr5:111885581-111885661 1 6.33e-04 . AATTATCT TCCAAAACAC chr2:10533327-10533407 24 6.75e-04 GAGCAATGAC TGTAATCT CTATCTGTCA chr2:217957626-217957706 40 6.92e-04 cagtcagatg gctaatca gcccagagcc chr17:33212288-33212368 10 6.92e-04 TACCACAAA GCTAATCA GCCACACATG chr2:158755879-158755959 46 7.50e-04 CTTAGTAAAA AATTATCA ACGTAGAACC chr6:119863407-119863487 17 7.89e-04 AAGCACATTT GGTAATCT AATTCTCTTG chr10:127293911-12729399 12 8.87e-04 AATGTGGTCA GTTAATCT CCATACACAG -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif BCTTATCW MEME-2 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr6:108880388-108880468 1.8e-05 71_[+2]_1 chrX:130086522-130086602 1.8e-05 70_[+2]_2 chr10:62022655-62022735 1.8e-05 57_[+2]_15 chr6:4177221-4177301 1.8e-05 72_[+2] chr1:48643126-48643206 1.8e-05 39_[+2]_33 chr9:131355491-131355571 3.4e-05 17_[+2]_55 chr7:115858315-115858395 3.4e-05 17_[+2]_55 chr16:81254217-81254297 3.4e-05 23_[+2]_49 chr3:42391380-42391460 3.4e-05 2_[+2]_70 chr17:57762504-57762584 3.4e-05 11_[+2]_61 chr22:30348257-30348337 3.4e-05 6_[+2]_66 chr4:99603973-99604053 3.4e-05 24_[+2]_48 chr1:230341606-230341686 3.4e-05 9_[+2]_63 chr11:67116039-67116119 6.7e-05 52_[+2]_20 chr6:159920213-159920293 6.7e-05 18_[+2]_54 chr12:92798843-92798923 6.7e-05 29_[+2]_43 chr1:206266182-206266262 6.7e-05 44_[+2]_28 chr16:66651869-66651949 6.7e-05 47_[+2]_25 chr1:101251443-101251523 6.7e-05 24_[+2]_48 chr4:10347164-10347244 6.7e-05 44_[+2]_28 chr4:79405857-79405937 6.7e-05 11_[+2]_61 chr7:148545022-148545102 6.7e-05 25_[+2]_47 chrX:39011780-39011860 6.7e-05 14_[+2]_58 chr1:51186307-51186387 6.7e-05 59_[+2]_13 chr1:214176684-214176764 6.7e-05 9_[+2]_63 chr4:96210548-96210628 8.6e-05 [+2]_72 chr3:170079718-170079798 8.6e-05 46_[+2]_26 chr3:32750308-32750388 8.6e-05 7_[+2]_65 chr3:133472769-133472849 0.0001 10_[+2]_62 chr21:32754500-32754580 0.0001 51_[+2]_21 chrX:107463299-107463379 0.00014 37_[+2]_35 chr5:89954577-89954657 0.00014 40_[+2]_32 chrX:119468577-119468657 0.00014 47_[+2]_25 chr2:84198848-84198928 0.00016 31_[+2]_41 chrX:40403744-40403824 0.00016 2_[+2]_70 chr11:422363-422443 0.00016 8_[+2]_64 chr9:125016706-125016786 0.00016 49_[+2]_23 chrX:49963276-49963356 0.00016 20_[+2]_52 chr3:151444006-151444086 0.00017 63_[+2]_9 chr7:5123117-5123197 0.00017 16_[+2]_56 chrX:45024397-45024477 0.00021 2_[+2]_70 chr10:96059329-96059409 0.00021 25_[+2]_47 chr9:86958274-86958354 0.00021 70_[+2]_2 chr2:178504405-178504485 0.00021 37_[+2]_35 chr7:127627082-127627162 0.00021 29_[+2]_43 chr2:30476952-30477032 0.00021 10_[+2]_62 chr3:154736918-154736998 0.00023 48_[+2]_24 chr2:46666870-46666950 0.00023 61_[+2]_11 chr22:40725269-40725349 0.00023 52_[+2]_20 chr9:127727085-127727165 0.00027 33_[+2]_39 chr8:97656729-97656809 0.00027 15_[+2]_57 chr16:22227757-22227837 0.00027 42_[+2]_30 chr18:67692991-67693071 0.00027 8_[+2]_64 chr2:68220641-68220721 0.00027 42_[+2]_30 chr10:126406632-12640671 0.00031 38_[+2]_34 chr4:81174848-81174928 0.00031 5_[+2]_67 chr17:33214019-33214099 0.00031 55_[+2]_17 chr12:60538339-60538419 0.00031 [+2]_72 chr6:123033599-123033679 0.00033 52_[+2]_20 chr1:95100703-95100783 0.00033 21_[+2]_51 chr18:75034062-75034142 0.00038 51_[+2]_21 chr1:204196621-204196701 0.00038 52_[+2]_20 chr7:134519773-134519853 0.00044 24_[+2]_48 chr22:40718275-40718355 0.00044 32_[+2]_40 chr12:89787579-89787659 0.00044 16_[+2]_56 chr5:169514580-169514660 0.00044 2_[+2]_70 chr13:44972150-44972230 0.00044 23_[+2]_49 chr15:64731399-64731479 0.00046 33_[+2]_39 chr1:45501483-45501563 0.0005 37_[+2]_35 chr2:178939662-178939742 0.0005 32_[+2]_40 chr7:104607697-104607777 0.00056 46_[+2]_26 chr2:145978784-145978864 0.00056 42_[+2]_30 chr1:70005901-70005981 0.00056 53_[+2]_19 chr1:39210366-39210446 0.00063 46_[+2]_26 chr8:23366395-23366475 0.00063 64_[+2]_8 chr2:74311079-74311159 0.00063 37_[+2]_35 chr11:59735657-59735737 0.00063 20_[+2]_52 chr8:56926571-56926651 0.00063 5_[+2]_67 chr6:21102063-21102143 0.00063 21_[+2]_51 chr5:111885581-111885661 0.00063 [+2]_72 chr2:10533327-10533407 0.00068 23_[+2]_49 chr2:217957626-217957706 0.00069 39_[+2]_33 chr17:33212288-33212368 0.00069 9_[+2]_63 chr2:158755879-158755959 0.00075 45_[+2]_27 chr6:119863407-119863487 0.00079 16_[+2]_56 chr10:127293911-12729399 0.00089 11_[+2]_61 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif BCTTATCW MEME-2 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF BCTTATCW width=8 seqs=86 chr6:108880388-108880468 ( 72) TCTTATCT 1 chrX:130086522-130086602 ( 71) TCTTATCT 1 chr10:62022655-62022735 ( 58) TCTTATCT 1 chr6:4177221-4177301 ( 73) TCTTATCT 1 chr1:48643126-48643206 ( 40) TCTTATCT 1 chr9:131355491-131355571 ( 18) GCTTATCT 1 chr7:115858315-115858395 ( 18) GCTTATCT 1 chr16:81254217-81254297 ( 24) GCTTATCT 1 chr3:42391380-42391460 ( 3) GCTTATCT 1 chr17:57762504-57762584 ( 12) GCTTATCT 1 chr22:30348257-30348337 ( 7) GCTTATCT 1 chr4:99603973-99604053 ( 25) GCTTATCT 1 chr1:230341606-230341686 ( 10) GCTTATCT 1 chr11:67116039-67116119 ( 53) CCTTATCT 1 chr6:159920213-159920293 ( 19) CCTTATCT 1 chr12:92798843-92798923 ( 30) CCTTATCT 1 chr1:206266182-206266262 ( 45) TCTTATCA 1 chr16:66651869-66651949 ( 48) CCTTATCT 1 chr1:101251443-101251523 ( 25) TCTTATCA 1 chr4:10347164-10347244 ( 45) CCTTATCT 1 chr4:79405857-79405937 ( 12) CCTTATCT 1 chr7:148545022-148545102 ( 26) CCTTATCT 1 chrX:39011780-39011860 ( 15) TCTTATCA 1 chr1:51186307-51186387 ( 60) TCTTATCA 1 chr1:214176684-214176764 ( 10) TCTTATCA 1 chr4:96210548-96210628 ( 1) TGTTATCT 1 chr3:170079718-170079798 ( 47) TGTTATCT 1 chr3:32750308-32750388 ( 8) TGTTATCT 1 chr3:133472769-133472849 ( 11) GCTTATCA 1 chr21:32754500-32754580 ( 52) GCTTATCA 1 chrX:107463299-107463379 ( 38) CCTTATCA 1 chr5:89954577-89954657 ( 41) CCTTATCA 1 chrX:119468577-119468657 ( 48) CCTTATCA 1 chr2:84198848-84198928 ( 32) TTTTATCT 1 chrX:40403744-40403824 ( 3) TTTTATCT 1 chr11:422363-422443 ( 9) TTTTATCT 1 chr9:125016706-125016786 ( 50) TTTTATCT 1 chrX:49963276-49963356 ( 21) TTTTATCT 1 chr3:151444006-151444086 ( 64) GGTTATCT 1 chr7:5123117-5123197 ( 17) GGTTATCT 1 chrX:45024397-45024477 ( 3) TGTTATCA 1 chr10:96059329-96059409 ( 26) TGTTATCA 1 chr9:86958274-86958354 ( 71) TGTTATCA 1 chr2:178504405-178504485 ( 38) TGTTATCA 1 chr7:127627082-127627162 ( 30) TGTTATCA 1 chr2:30476952-30477032 ( 11) CGTTATCT 1 chr3:154736918-154736998 ( 49) TATTATCT 1 chr2:46666870-46666950 ( 62) TATTATCT 1 chr22:40725269-40725349 ( 53) TATTATCT 1 chr9:127727085-127727165 ( 34) GTTTATCT 1 chr8:97656729-97656809 ( 16) ACTTATCA 1 chr16:22227757-22227837 ( 43) ACTTATCA 1 chr18:67692991-67693071 ( 9) GTTTATCT 1 chr2:68220641-68220721 ( 43) ACTTATCA 1 chr10:126406632-12640671 ( 39) CTTTATCT 1 chr4:81174848-81174928 ( 6) CTTTATCT 1 chr17:33214019-33214099 ( 56) TTTTATCA 1 chr12:60538339-60538419 ( 1) TTTTATCA 1 chr6:123033599-123033679 ( 53) GGTTATCA 1 chr1:95100703-95100783 ( 22) GGTTATCA 1 chr18:75034062-75034142 ( 52) CGTTATCA 1 chr1:204196621-204196701 ( 53) AGTTATCT 1 chr7:134519773-134519853 ( 25) TCTAATCT 1 chr22:40718275-40718355 ( 33) TATTATCA 1 chr12:89787579-89787659 ( 17) TCTAATCT 1 chr5:169514580-169514660 ( 3) CATTATCT 1 chr13:44972150-44972230 ( 24) CATTATCT 1 chr15:64731399-64731479 ( 34) GTTTATCA 1 chr1:45501483-45501563 ( 38) ATTTATCT 1 chr2:178939662-178939742 ( 33) ATTTATCT 1 chr7:104607697-104607777 ( 47) GATTATCA 1 chr2:145978784-145978864 ( 43) AGTTATCA 1 chr1:70005901-70005981 ( 54) AGTTATCA 1 chr1:39210366-39210446 ( 47) AATTATCT 1 chr8:23366395-23366475 ( 65) TCTAATCA 1 chr2:74311079-74311159 ( 38) CCTAATCT 1 chr11:59735657-59735737 ( 21) AATTATCT 1 chr8:56926571-56926651 ( 6) AATTATCT 1 chr6:21102063-21102143 ( 22) TCTAATCA 1 chr5:111885581-111885661 ( 1) AATTATCT 1 chr2:10533327-10533407 ( 24) TGTAATCT 1 chr2:217957626-217957706 ( 40) GCTAATCA 1 chr17:33212288-33212368 ( 10) GCTAATCA 1 chr2:158755879-158755959 ( 46) AATTATCA 1 chr6:119863407-119863487 ( 17) GGTAATCT 1 chr10:127293911-12729399 ( 12) GTTAATCT 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif BCTTATCW MEME-2 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 9.59303 E= 8.5e-025 -85 -18 10 58 -97 106 -11 -60 -1307 -1307 -1307 192 -123 -1307 -1307 174 187 -1307 -1307 -1307 -1307 -1307 -1307 192 -1307 216 -1307 -1307 49 -1307 -1307 122 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif BCTTATCW MEME-2 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 86 E= 8.5e-025 0.151163 0.197674 0.255814 0.395349 0.139535 0.465116 0.220930 0.174419 0.000000 0.000000 0.000000 1.000000 0.116279 0.000000 0.000000 0.883721 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 0.383721 0.000000 0.000000 0.616279 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif BCTTATCW MEME-2 regular expression -------------------------------------------------------------------------------- [TG][CG]TTATC[TA] -------------------------------------------------------------------------------- Time 8.64 secs. ******************************************************************************** ******************************************************************************** MOTIF VCAGCTGS MEME-3 width = 8 sites = 112 llr = 768 E-value = 1.6e-029 ******************************************************************************** -------------------------------------------------------------------------------- Motif VCAGCTGS MEME-3 Description -------------------------------------------------------------------------------- Simplified A 4:9:32:: pos.-specific C 4a::6::4 probability G 3::71:a4 matrix T ::13:8:2 bits 2.2 * * 1.9 * * 1.7 * * 1.5 * * Relative 1.3 ** ** Entropy 1.1 *** ** (9.9 bits) 0.9 ****** 0.6 ******* 0.4 ******** 0.2 ******** 0.0 -------- Multilevel ACAGCTGG consensus C TA C sequence G -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif VCAGCTGS MEME-3 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr1:206909005-206909085 45 1.10e-05 cttctctgac ccagctgg tgtgataaga chr22:30348257-30348337 22 3.46e-05 TCTGTGCCCC ACAGCTGG CAGAGTAATG chr5:168240747-168240827 9 3.46e-05 GGCTCCAG ACAGCTGG ATTTAATTCA chr2:48679410-48679490 12 3.46e-05 AGGCGTGGTG ACAGCTGG TTctattgat chr1:234740753-234740833 13 3.46e-05 TGCCCTTTCC ACAGCTGG ATAGACTTAT chr10:126406632-12640671 17 4.71e-05 GCCTTGGAAC ACAGCTGC GAGGGCAGTG chr4:96210548-96210628 65 4.71e-05 TTAAGCAAAT ACAGCTGC TGTACTAT chr20:5469588-5469668 12 4.71e-05 ttcaattacg acagctgc ttccagaaga chr2:68220641-68220721 29 4.71e-05 CCCTTCTCAG ACAGCTGC AGTAACACTT chr5:148126515-148126595 48 5.88e-05 TAGCTACTTG GCAGCTGG GGAGTAAAGA chr9:127727085-127727165 25 5.88e-05 tgttgtactg gcagctgg tgtttatctt chr1:179941155-179941235 29 5.88e-05 TCTGGTTTAT GCAGCTGG ATGACTGAGA chr1:95113903-95113983 25 5.88e-05 ATCTGTTTAG GCAGCTGG CGCATTTCCG chr4:81174848-81174928 66 6.98e-05 GCTCACCCAA GCAGCTGC CAGTGCT chr18:33039029-33039109 15 6.98e-05 CCTCCTTATC GCAGCTGC AGGCAGCCTG chr2:27197335-27197415 72 6.98e-05 TGCACATTGG GCAGCTGC G chr4:129268783-129268863 59 9.53e-05 tttcatcacc ccagatgg aaacaggaga chr6:80314395-80314475 58 9.53e-05 tcactggttt ccagatgg agagaaggca chr2:158755879-158755959 19 9.53e-05 TGACCTTAGA CCAGATGG TCCCTGTGGC chr6:21102063-21102143 57 9.53e-05 atcctacctc ccagctgt taatcagatc chr1:45362178-45362258 13 9.53e-05 ATTCTTTTCT CCAGATGG TCGGAGATAC chr12:65114788-65114868 46 9.53e-05 ATGAGGGTTG CCAGATGG GGCAGGTGAG chr10:82531902-82531982 17 1.08e-04 ggctagcatg ccagatgc acggatgagg chr4:25052511-25052591 72 1.08e-04 AACAGTAAGT CCAGATGC G chr6:161665886-161665966 13 1.51e-04 CCAACCACAG ACAGATGG GCCAAAACCC chr20:20927143-20927223 45 1.51e-04 GGGGCTCAAA ACAGCTGT GAACAATTTC chr7:102082193-102082273 25 1.51e-04 AGCAAGTGAA CCATCTGG CGTGGAGCTG chr15:39432297-39432377 31 1.51e-04 TGATAAGAGC ACAGCTGT GGGAAAGCCA chr19:14253631-14253711 14 1.51e-04 tcactgctat acagctgt gctgataagg chrX:40403744-40403824 55 1.51e-04 AGATATGGTT CCATCTGG TTTTGCTGGG chr4:122715802-122715882 55 1.51e-04 gttcactgta acagatgg accacactga chr18:75034062-75034142 67 1.51e-04 tcagaagtga aCAGCTGT GTTTAT chr1:209819337-209819417 26 1.51e-04 gataaaaatg acagctgt ttggcttaga chr7:119566125-119566205 73 1.51e-04 GTCAGCCAGG CCATCTGG chr1:214593156-214593236 15 1.51e-04 GCGGGTGTTC ACAGCTGT AAATCCAGAT chr6:109606071-109606151 60 1.51e-04 TGGCTCTTAA CCATCTGG TCACCTGATA chr10:63540244-63540324 63 1.51e-04 TCTGAGCTTA CCATCTGG GTGGCCTACG chr1:214176684-214176764 67 1.51e-04 ATCCATTTGG ACAGATGG TCCTGA chr2:84198848-84198928 67 1.78e-04 GGATAAAAAT CCATCTGC AGAGTG chr1:45501483-45501563 54 1.78e-04 CTGTATGCTT CCATCTGC CAGCCTGGAC chr6:20575569-20575649 38 1.78e-04 TCTGCGGGGA CCATCTGC TGTGGTTCCC chr2:15696580-15696660 37 1.78e-04 TATGCAGGCT ACAGATGC TTCATATGGA chr5:95220353-95220433 65 1.78e-04 ggttaggaac acagatgc tgtggtca chr9:131355491-131355571 44 2.20e-04 GCTTCCATGT GCAGCTGT GTGTTCAGAG chr8:23366395-23366475 27 2.20e-04 TGGCCTGAGA GCAGATGG TTTCCGATAT chr11:422363-422443 23 2.20e-04 atctcacaag gcagatgg tattaaggct chr6:4177221-4177301 16 2.20e-04 gaagaagaca acatctgg ggtagactgc chr7:116079238-116079318 46 2.20e-04 ATACCGTGAA ACATCTGG TAGATGGGAG chr5:29796337-29796417 67 2.20e-04 ACCAGACACT GCAGATGG TGACTC chr9:130188248-130188328 22 2.20e-04 ggaaagcaga gcagatgg gtcgtcatct chr8:106532850-106532930 5 2.20e-04 AGGA GCAGATGG TTGATTGTGA chr7:24903968-24904048 39 2.20e-04 tttattccat acatctgg gttgagcctg chr9:90419029-90419109 2 2.47e-04 A ACATCTGC AAGCTAATGA chr9:125016706-125016786 36 2.47e-04 TCTTGCTTTC ACATCTGC AAGCACTTTT chr8:49379267-49379347 61 2.47e-04 gaccctctgg gcagatgc gcacttaacc chr3:142337811-142337891 64 2.84e-04 GTTATCGCTA CCAGCAGG GCTCCAAGC chr20:30082073-30082153 34 2.84e-04 cacattccag ccagcagg aagcggtaag chr8:23526275-23526355 72 2.84e-04 AGCTAGGTTA GCATCTGC A chr6:126439349-126439429 43 3.05e-04 GCCCACAAAA CCAGCAGC AGGCCCTCTC chr16:21272959-21273039 9 3.05e-04 CATGCATG CCAGCAGC TCCCTTCTTG chr13:99628332-99628412 8 3.05e-04 TGTTTAC CCTGCTGG AAGAAGAGAA chr11:68899174-68899254 72 3.05e-04 GAGGGCTTTG CCTGCTGG C chr9:101553585-101553665 39 3.05e-04 CCTGCTGCCA CCTGCTGG CAGGAATGTT chr22:40718275-40718355 5 3.44e-04 atct cctgctgc cacacatgaa chr1:109677204-109677284 51 3.44e-04 GGCTGCTGCA CCTGCTGC TTTTGCCGTT chr14:31291369-31291449 10 3.44e-04 gtaagttcc cctgctgc tctgttccca chr3:133472769-133472849 26 3.44e-04 TCAGAGAAAC ACAGCAGG CTGTGTGCAG chr20:9129850-9129930 20 3.70e-04 ccttttctcc acagcagc ctgatctcca chr20:37192564-37192644 6 3.70e-04 atacc acagcagc ctgaagagga chr2:74311079-74311159 5 4.52e-04 GTCC ACAGATGT GCGTCGATGC chr6:138172498-138172578 9 4.52e-04 gacagaga ccatatgg cccacaaagc chr7:104607697-104607777 2 4.52e-04 A CCAGGTGG GCTGAGTAGA chr15:35459071-35459151 19 4.52e-04 TCATTCTCAA GCAGCAGG GAAAAGGAGC chr3:105333306-105333386 51 4.52e-04 GTCAACAGCA ACTGCTGC TTGGAAAGAG chr7:10747317-10747397 13 4.52e-04 gcagtctgta gcagcagg ctagagagat chr4:10013706-10013786 27 4.52e-04 gcaacagaga ccatatgg ccaacaaaga chr16:50105138-50105218 44 4.52e-04 ACCTAAAAGC ACAGATGT TTCTTAGAAT chr6:164767864-164767944 4 4.52e-04 TGG CCAGGTGG GGGAGCACAG chrX:122598706-122598786 64 4.52e-04 ATCAGCGGAG CCATCTGT GTTTACCAA chr8:2645835-2645915 21 4.52e-04 cttaaccctc actgctgc aggattgctg chr2:37843915-37843995 63 4.52e-04 GAGCCATGGA ACAGATGT TTGCGGTTTA chrX:107463299-107463379 52 5.00e-04 atcaaatgga ccaggtgc aattcctgct chr4:109035778-109035858 64 5.00e-04 AATACTGTGA GCAGCAGC CAAAGAGCA chr1:213779222-213779302 3 5.00e-04 cg ccaggtgc tgagaaggat chr5:131987918-131987998 9 5.00e-04 GTAATAgg ccaggtgc agtggctgat chr10:14223352-14223432 2 5.75e-04 A GCTGCTGC AGCCCCAGAT chr3:170079718-170079798 6 5.75e-04 CCACT ACATCTGT TGTTTTTCTA chr6:13355805-13355885 73 5.75e-04 AATTTACCCA GCAGATGT chr16:66651869-66651949 16 5.75e-04 CTGATAGCAG ACAGGTGG GGTGTTCCAG chr19:16308205-16308285 70 5.75e-04 gttgacaatg acaggtgg tga chrX:109202815-109202895 20 5.75e-04 ttcagttgcc acatctgt aaaagggaga chr1:48643126-48643206 55 5.75e-04 tctatggccg gcagatgt tgggtgcagt chr13:44972150-44972230 64 5.75e-04 TTAGCACAGA GCAGATGT CCCAGGCCT chr4:20700585-20700665 61 6.06e-04 actccagaac acatatgc ttgtcattcc chr3:143734116-143734196 27 6.06e-04 GAGAAGAAGG ACATATGC CCATTGCGGT chr15:50886658-50886738 5 6.06e-04 TCTT ACATATGC AGCAAAACAG chr12:60538339-60538419 15 6.49e-04 atcatgatca gcatctgt ggggtatgct chr5:10708805-10708885 27 6.49e-04 GTGCGGTTGT GCAGGTGG ACTCCTACAC chr2:217957626-217957706 56 7.39e-04 cagcccagag ccagaaGC TGCTTGCAGG chrX:39011780-39011860 2 7.39e-04 T CCTGCTGT TTTTCTCTTA chrX:45024397-45024477 25 7.96e-04 AGCCTAGGGA ACAGAAGG GGAGCAAGGG chr8:87522864-87522944 36 8.66e-04 ttcctaaacc acagaagc tatgacagat chr16:55469427-55469507 23 8.66e-04 TCTGGCCTTC CCATCAGC CTCGCCTTTC chrX:49963276-49963356 57 8.66e-04 ATCTTGCTGT CCTTCTGG GTTGTAGAGA chr1:26087554-26087634 5 8.66e-04 gtgg ccatcagc aagtcaccag chr7:66387286-66387366 30 8.66e-04 CTCGATAGCA CCATCAGC TTGGGTCAGC chr14:55850704-55850784 15 9.65e-04 TCGTATCTTT CCTTCTGC CACAACATAC chr14:75177348-75177428 51 9.65e-04 ATGGGGTAAA GCAGAAGG CACATACAGT chr11:108094347-10809442 50 1.03e-03 GTGAGCGTTA GCTGCTGT ATTTACCAGG chr2:64582057-64582137 17 1.12e-03 CCACAAGCAA ACTTCTGC ATACTCAGGA chr6:32256394-32256474 9 1.16e-03 GTGCTCAA GCTTCTGG ATGATGATAG chrX:134996735-134996815 16 1.23e-03 aactctgcag gcaggtgt catataagag -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif VCAGCTGS MEME-3 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr1:206909005-206909085 1.1e-05 44_[+3]_28 chr22:30348257-30348337 3.5e-05 21_[+3]_51 chr5:168240747-168240827 3.5e-05 8_[+3]_64 chr2:48679410-48679490 3.5e-05 11_[+3]_61 chr1:234740753-234740833 3.5e-05 12_[+3]_60 chr10:126406632-12640671 4.7e-05 16_[+3]_56 chr4:96210548-96210628 4.7e-05 64_[+3]_8 chr20:5469588-5469668 4.7e-05 11_[+3]_61 chr2:68220641-68220721 4.7e-05 28_[+3]_44 chr5:148126515-148126595 5.9e-05 47_[+3]_25 chr9:127727085-127727165 5.9e-05 24_[+3]_48 chr1:179941155-179941235 5.9e-05 28_[+3]_44 chr1:95113903-95113983 5.9e-05 24_[+3]_48 chr4:81174848-81174928 7e-05 65_[+3]_7 chr18:33039029-33039109 7e-05 14_[+3]_58 chr2:27197335-27197415 7e-05 71_[+3]_1 chr4:129268783-129268863 9.5e-05 58_[+3]_14 chr6:80314395-80314475 9.5e-05 57_[+3]_15 chr2:158755879-158755959 9.5e-05 18_[+3]_54 chr6:21102063-21102143 9.5e-05 56_[+3]_16 chr1:45362178-45362258 9.5e-05 12_[+3]_60 chr12:65114788-65114868 9.5e-05 45_[+3]_27 chr10:82531902-82531982 0.00011 16_[+3]_56 chr4:25052511-25052591 0.00011 71_[+3]_1 chr6:161665886-161665966 0.00015 12_[+3]_60 chr20:20927143-20927223 0.00015 44_[+3]_28 chr7:102082193-102082273 0.00015 24_[+3]_48 chr15:39432297-39432377 0.00015 30_[+3]_42 chr19:14253631-14253711 0.00015 13_[+3]_59 chrX:40403744-40403824 0.00015 54_[+3]_18 chr4:122715802-122715882 0.00015 54_[+3]_18 chr18:75034062-75034142 0.00015 66_[+3]_6 chr1:209819337-209819417 0.00015 25_[+3]_47 chr7:119566125-119566205 0.00015 72_[+3] chr1:214593156-214593236 0.00015 14_[+3]_58 chr6:109606071-109606151 0.00015 59_[+3]_13 chr10:63540244-63540324 0.00015 62_[+3]_10 chr1:214176684-214176764 0.00015 66_[+3]_6 chr2:84198848-84198928 0.00018 66_[+3]_6 chr1:45501483-45501563 0.00018 53_[+3]_19 chr6:20575569-20575649 0.00018 37_[+3]_35 chr2:15696580-15696660 0.00018 36_[+3]_36 chr5:95220353-95220433 0.00018 64_[+3]_8 chr9:131355491-131355571 0.00022 43_[+3]_29 chr8:23366395-23366475 0.00022 26_[+3]_46 chr11:422363-422443 0.00022 22_[+3]_50 chr6:4177221-4177301 0.00022 15_[+3]_57 chr7:116079238-116079318 0.00022 45_[+3]_27 chr5:29796337-29796417 0.00022 66_[+3]_6 chr9:130188248-130188328 0.00022 21_[+3]_51 chr8:106532850-106532930 0.00022 4_[+3]_68 chr7:24903968-24904048 0.00022 38_[+3]_34 chr9:90419029-90419109 0.00025 1_[+3]_71 chr9:125016706-125016786 0.00025 35_[+3]_37 chr8:49379267-49379347 0.00025 60_[+3]_12 chr3:142337811-142337891 0.00028 63_[+3]_9 chr20:30082073-30082153 0.00028 33_[+3]_39 chr8:23526275-23526355 0.00028 71_[+3]_1 chr6:126439349-126439429 0.00031 42_[+3]_30 chr16:21272959-21273039 0.00031 8_[+3]_64 chr13:99628332-99628412 0.00031 7_[+3]_65 chr11:68899174-68899254 0.00031 71_[+3]_1 chr9:101553585-101553665 0.00031 38_[+3]_34 chr22:40718275-40718355 0.00034 4_[+3]_68 chr1:109677204-109677284 0.00034 50_[+3]_22 chr14:31291369-31291449 0.00034 9_[+3]_63 chr3:133472769-133472849 0.00034 25_[+3]_47 chr20:9129850-9129930 0.00037 19_[+3]_53 chr20:37192564-37192644 0.00037 5_[+3]_67 chr2:74311079-74311159 0.00045 4_[+3]_68 chr6:138172498-138172578 0.00045 8_[+3]_64 chr7:104607697-104607777 0.00045 1_[+3]_71 chr15:35459071-35459151 0.00045 18_[+3]_54 chr3:105333306-105333386 0.00045 50_[+3]_22 chr7:10747317-10747397 0.00045 12_[+3]_60 chr4:10013706-10013786 0.00045 26_[+3]_46 chr16:50105138-50105218 0.00045 43_[+3]_29 chr6:164767864-164767944 0.00045 3_[+3]_69 chrX:122598706-122598786 0.00045 63_[+3]_9 chr8:2645835-2645915 0.00045 20_[+3]_52 chr2:37843915-37843995 0.00045 62_[+3]_10 chrX:107463299-107463379 0.0005 51_[+3]_21 chr4:109035778-109035858 0.0005 63_[+3]_9 chr1:213779222-213779302 0.0005 2_[+3]_70 chr5:131987918-131987998 0.0005 8_[+3]_64 chr10:14223352-14223432 0.00058 1_[+3]_71 chr3:170079718-170079798 0.00058 5_[+3]_67 chr6:13355805-13355885 0.00058 72_[+3] chr16:66651869-66651949 0.00058 15_[+3]_57 chr19:16308205-16308285 0.00058 69_[+3]_3 chrX:109202815-109202895 0.00058 19_[+3]_53 chr1:48643126-48643206 0.00058 54_[+3]_18 chr13:44972150-44972230 0.00058 63_[+3]_9 chr4:20700585-20700665 0.00061 60_[+3]_12 chr3:143734116-143734196 0.00061 26_[+3]_46 chr15:50886658-50886738 0.00061 4_[+3]_68 chr12:60538339-60538419 0.00065 14_[+3]_58 chr5:10708805-10708885 0.00065 26_[+3]_46 chr2:217957626-217957706 0.00074 55_[+3]_17 chrX:39011780-39011860 0.00074 1_[+3]_71 chrX:45024397-45024477 0.0008 24_[+3]_48 chr8:87522864-87522944 0.00087 35_[+3]_37 chr16:55469427-55469507 0.00087 22_[+3]_50 chrX:49963276-49963356 0.00087 56_[+3]_16 chr1:26087554-26087634 0.00087 4_[+3]_68 chr7:66387286-66387366 0.00087 29_[+3]_43 chr14:55850704-55850784 0.00096 14_[+3]_58 chr14:75177348-75177428 0.00096 50_[+3]_22 chr11:108094347-10809442 0.001 49_[+3]_23 chr2:64582057-64582137 0.0011 16_[+3]_56 chr6:32256394-32256474 0.0012 8_[+3]_64 chrX:134996735-134996815 0.0012 15_[+3]_57 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif VCAGCTGS MEME-3 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF VCAGCTGS width=8 seqs=112 chr1:206909005-206909085 ( 45) CCAGCTGG 1 chr22:30348257-30348337 ( 22) ACAGCTGG 1 chr5:168240747-168240827 ( 9) ACAGCTGG 1 chr2:48679410-48679490 ( 12) ACAGCTGG 1 chr1:234740753-234740833 ( 13) ACAGCTGG 1 chr10:126406632-12640671 ( 17) ACAGCTGC 1 chr4:96210548-96210628 ( 65) ACAGCTGC 1 chr20:5469588-5469668 ( 12) ACAGCTGC 1 chr2:68220641-68220721 ( 29) ACAGCTGC 1 chr5:148126515-148126595 ( 48) GCAGCTGG 1 chr9:127727085-127727165 ( 25) GCAGCTGG 1 chr1:179941155-179941235 ( 29) GCAGCTGG 1 chr1:95113903-95113983 ( 25) GCAGCTGG 1 chr4:81174848-81174928 ( 66) GCAGCTGC 1 chr18:33039029-33039109 ( 15) GCAGCTGC 1 chr2:27197335-27197415 ( 72) GCAGCTGC 1 chr4:129268783-129268863 ( 59) CCAGATGG 1 chr6:80314395-80314475 ( 58) CCAGATGG 1 chr2:158755879-158755959 ( 19) CCAGATGG 1 chr6:21102063-21102143 ( 57) CCAGCTGT 1 chr1:45362178-45362258 ( 13) CCAGATGG 1 chr12:65114788-65114868 ( 46) CCAGATGG 1 chr10:82531902-82531982 ( 17) CCAGATGC 1 chr4:25052511-25052591 ( 72) CCAGATGC 1 chr6:161665886-161665966 ( 13) ACAGATGG 1 chr20:20927143-20927223 ( 45) ACAGCTGT 1 chr7:102082193-102082273 ( 25) CCATCTGG 1 chr15:39432297-39432377 ( 31) ACAGCTGT 1 chr19:14253631-14253711 ( 14) ACAGCTGT 1 chrX:40403744-40403824 ( 55) CCATCTGG 1 chr4:122715802-122715882 ( 55) ACAGATGG 1 chr18:75034062-75034142 ( 67) ACAGCTGT 1 chr1:209819337-209819417 ( 26) ACAGCTGT 1 chr7:119566125-119566205 ( 73) CCATCTGG 1 chr1:214593156-214593236 ( 15) ACAGCTGT 1 chr6:109606071-109606151 ( 60) CCATCTGG 1 chr10:63540244-63540324 ( 63) CCATCTGG 1 chr1:214176684-214176764 ( 67) ACAGATGG 1 chr2:84198848-84198928 ( 67) CCATCTGC 1 chr1:45501483-45501563 ( 54) CCATCTGC 1 chr6:20575569-20575649 ( 38) CCATCTGC 1 chr2:15696580-15696660 ( 37) ACAGATGC 1 chr5:95220353-95220433 ( 65) ACAGATGC 1 chr9:131355491-131355571 ( 44) GCAGCTGT 1 chr8:23366395-23366475 ( 27) GCAGATGG 1 chr11:422363-422443 ( 23) GCAGATGG 1 chr6:4177221-4177301 ( 16) ACATCTGG 1 chr7:116079238-116079318 ( 46) ACATCTGG 1 chr5:29796337-29796417 ( 67) GCAGATGG 1 chr9:130188248-130188328 ( 22) GCAGATGG 1 chr8:106532850-106532930 ( 5) GCAGATGG 1 chr7:24903968-24904048 ( 39) ACATCTGG 1 chr9:90419029-90419109 ( 2) ACATCTGC 1 chr9:125016706-125016786 ( 36) ACATCTGC 1 chr8:49379267-49379347 ( 61) GCAGATGC 1 chr3:142337811-142337891 ( 64) CCAGCAGG 1 chr20:30082073-30082153 ( 34) CCAGCAGG 1 chr8:23526275-23526355 ( 72) GCATCTGC 1 chr6:126439349-126439429 ( 43) CCAGCAGC 1 chr16:21272959-21273039 ( 9) CCAGCAGC 1 chr13:99628332-99628412 ( 8) CCTGCTGG 1 chr11:68899174-68899254 ( 72) CCTGCTGG 1 chr9:101553585-101553665 ( 39) CCTGCTGG 1 chr22:40718275-40718355 ( 5) CCTGCTGC 1 chr1:109677204-109677284 ( 51) CCTGCTGC 1 chr14:31291369-31291449 ( 10) CCTGCTGC 1 chr3:133472769-133472849 ( 26) ACAGCAGG 1 chr20:9129850-9129930 ( 20) ACAGCAGC 1 chr20:37192564-37192644 ( 6) ACAGCAGC 1 chr2:74311079-74311159 ( 5) ACAGATGT 1 chr6:138172498-138172578 ( 9) CCATATGG 1 chr7:104607697-104607777 ( 2) CCAGGTGG 1 chr15:35459071-35459151 ( 19) GCAGCAGG 1 chr3:105333306-105333386 ( 51) ACTGCTGC 1 chr7:10747317-10747397 ( 13) GCAGCAGG 1 chr4:10013706-10013786 ( 27) CCATATGG 1 chr16:50105138-50105218 ( 44) ACAGATGT 1 chr6:164767864-164767944 ( 4) CCAGGTGG 1 chrX:122598706-122598786 ( 64) CCATCTGT 1 chr8:2645835-2645915 ( 21) ACTGCTGC 1 chr2:37843915-37843995 ( 63) ACAGATGT 1 chrX:107463299-107463379 ( 52) CCAGGTGC 1 chr4:109035778-109035858 ( 64) GCAGCAGC 1 chr1:213779222-213779302 ( 3) CCAGGTGC 1 chr5:131987918-131987998 ( 9) CCAGGTGC 1 chr10:14223352-14223432 ( 2) GCTGCTGC 1 chr3:170079718-170079798 ( 6) ACATCTGT 1 chr6:13355805-13355885 ( 73) GCAGATGT 1 chr16:66651869-66651949 ( 16) ACAGGTGG 1 chr19:16308205-16308285 ( 70) ACAGGTGG 1 chrX:109202815-109202895 ( 20) ACATCTGT 1 chr1:48643126-48643206 ( 55) GCAGATGT 1 chr13:44972150-44972230 ( 64) GCAGATGT 1 chr4:20700585-20700665 ( 61) ACATATGC 1 chr3:143734116-143734196 ( 27) ACATATGC 1 chr15:50886658-50886738 ( 5) ACATATGC 1 chr12:60538339-60538419 ( 15) GCATCTGT 1 chr5:10708805-10708885 ( 27) GCAGGTGG 1 chr2:217957626-217957706 ( 56) CCAGAAGC 1 chrX:39011780-39011860 ( 2) CCTGCTGT 1 chrX:45024397-45024477 ( 25) ACAGAAGG 1 chr8:87522864-87522944 ( 36) ACAGAAGC 1 chr16:55469427-55469507 ( 23) CCATCAGC 1 chrX:49963276-49963356 ( 57) CCTTCTGG 1 chr1:26087554-26087634 ( 5) CCATCAGC 1 chr7:66387286-66387366 ( 30) CCATCAGC 1 chr14:55850704-55850784 ( 15) CCTTCTGC 1 chr14:75177348-75177428 ( 51) GCAGAAGG 1 chr11:108094347-10809442 ( 50) GCTGCTGT 1 chr2:64582057-64582137 ( 17) ACTTCTGC 1 chr6:32256394-32256474 ( 9) GCTTCTGG 1 chrX:134996735-134996815 ( 16) GCAGGTGT 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif VCAGCTGS MEME-3 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 8.56685 E= 1.6e-029 46 75 7 -1345 -1345 216 -1345 -1345 166 -1345 -1345 -98 -1345 -1345 162 2 11 148 -157 -1345 -85 -1345 -1345 168 -1345 -1345 207 -1345 -1345 75 88 -50 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif VCAGCTGS MEME-3 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 112 E= 1.6e-029 0.375000 0.375000 0.250000 0.000000 0.000000 1.000000 0.000000 0.000000 0.866071 0.000000 0.000000 0.133929 0.000000 0.000000 0.732143 0.267857 0.294643 0.625000 0.080357 0.000000 0.151786 0.000000 0.000000 0.848214 0.000000 0.000000 1.000000 0.000000 0.000000 0.375000 0.437500 0.187500 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif VCAGCTGS MEME-3 regular expression -------------------------------------------------------------------------------- [ACG]CA[GT][CA]TG[GC] -------------------------------------------------------------------------------- Time 12.09 secs. ******************************************************************************** ******************************************************************************** MOTIF YCTGTGGT MEME-4 width = 8 sites = 18 llr = 168 E-value = 3.6e+001 ******************************************************************************** -------------------------------------------------------------------------------- Motif YCTGTGGT MEME-4 Description -------------------------------------------------------------------------------- Simplified A 1::::::: pos.-specific C 6a:1:::1 probability G 1::9:aa1 matrix T 3:a:a::8 bits 2.2 * ** 1.9 ** *** 1.7 ** *** 1.5 ****** Relative 1.3 ****** Entropy 1.1 ******* (13.5 bits) 0.9 ******* 0.6 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel CCTGTGGT consensus T sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YCTGTGGT MEME-4 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr1:39210366-39210446 34 1.26e-05 ggaataaatt cctgtggt ttgtaaatta chr11:108094347-10809442 24 1.26e-05 ATAATCTTGA CCTGTGGT GAGCACTCGT chr8:86290464-86290544 14 1.26e-05 gatgtctggc cctgtggt gattagagtg chrX:130086522-130086602 60 1.26e-05 agtctttagc cctgtggt ttgtcttatc chr2:160353944-160354024 51 1.26e-05 TGGTCCCATT CCTGTGGT CAAAGCTGTC chr6:150881280-150881360 23 1.26e-05 tgaccaccac cctgtggt gaccatcaca chr1:206909005-206909085 25 2.76e-05 ttctgatcct tctgtggt cacttctctg chr12:92798843-92798923 4 2.76e-05 TTA TCTGTGGT ATCCACCCGC chr1:101251443-101251523 9 2.76e-05 agaaccat tctgtggt tggcggtctc chr7:117581637-117581717 25 2.76e-05 gccacctgtc tctgtggt cattcattcc chr13:44972150-44972230 34 2.76e-05 CATTATCTCC TCTGTGGT CTGCCTCGGA chr2:10533327-10533407 67 3.83e-05 CCAGGGAGCC CCTGTGGC TTAGAG chr2:158755879-158755959 29 3.83e-05 CCAGATGGTC CCTGTGGC TTAGTAAAAA chr15:67066819-67066899 40 5.01e-05 CAGCCACCAC CCTCTGGT GGCAGGAATG chr20:5469588-5469668 35 6.36e-05 gaagataggg gctgtggt gagaacagAa chr1:45362178-45362258 39 9.17e-05 ACCTCTTGCT ACTGTGGT ATCTGTTCAC chr7:44120948-44121028 20 1.17e-04 acatatccac cctgtggg gttgttgtac chr3:32750308-32750388 58 1.17e-04 CTTGCAGAAT TCTCTGGT ACTTTTACCT -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YCTGTGGT MEME-4 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr1:39210366-39210446 1.3e-05 33_[+4]_39 chr11:108094347-10809442 1.3e-05 23_[+4]_49 chr8:86290464-86290544 1.3e-05 13_[+4]_59 chrX:130086522-130086602 1.3e-05 59_[+4]_13 chr2:160353944-160354024 1.3e-05 50_[+4]_22 chr6:150881280-150881360 1.3e-05 22_[+4]_50 chr1:206909005-206909085 2.8e-05 24_[+4]_48 chr12:92798843-92798923 2.8e-05 3_[+4]_69 chr1:101251443-101251523 2.8e-05 8_[+4]_64 chr7:117581637-117581717 2.8e-05 24_[+4]_48 chr13:44972150-44972230 2.8e-05 33_[+4]_39 chr2:10533327-10533407 3.8e-05 66_[+4]_6 chr2:158755879-158755959 3.8e-05 28_[+4]_44 chr15:67066819-67066899 5e-05 39_[+4]_33 chr20:5469588-5469668 6.4e-05 34_[+4]_38 chr1:45362178-45362258 9.2e-05 38_[+4]_34 chr7:44120948-44121028 0.00012 19_[+4]_53 chr3:32750308-32750388 0.00012 57_[+4]_15 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YCTGTGGT MEME-4 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF YCTGTGGT width=8 seqs=18 chr1:39210366-39210446 ( 34) CCTGTGGT 1 chr11:108094347-10809442 ( 24) CCTGTGGT 1 chr8:86290464-86290544 ( 14) CCTGTGGT 1 chrX:130086522-130086602 ( 60) CCTGTGGT 1 chr2:160353944-160354024 ( 51) CCTGTGGT 1 chr6:150881280-150881360 ( 23) CCTGTGGT 1 chr1:206909005-206909085 ( 25) TCTGTGGT 1 chr12:92798843-92798923 ( 4) TCTGTGGT 1 chr1:101251443-101251523 ( 9) TCTGTGGT 1 chr7:117581637-117581717 ( 25) TCTGTGGT 1 chr13:44972150-44972230 ( 34) TCTGTGGT 1 chr2:10533327-10533407 ( 67) CCTGTGGC 1 chr2:158755879-158755959 ( 29) CCTGTGGC 1 chr15:67066819-67066899 ( 40) CCTCTGGT 1 chr20:5469588-5469668 ( 35) GCTGTGGT 1 chr1:45362178-45362258 ( 39) ACTGTGGT 1 chr7:44120948-44121028 ( 20) CCTGTGGG 1 chr3:32750308-32750388 ( 58) TCTCTGGT 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YCTGTGGT MEME-4 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 10.1187 E= 3.6e+001 -230 131 -210 33 -1081 216 -1081 -1081 -1081 -1081 -1081 192 -1081 -101 190 -1081 -1081 -1081 -1081 192 -1081 -1081 207 -1081 -1081 -1081 207 -1081 -1081 -101 -210 165 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YCTGTGGT MEME-4 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 18 E= 3.6e+001 0.055556 0.555556 0.055556 0.333333 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.111111 0.888889 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.111111 0.055556 0.833333 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YCTGTGGT MEME-4 regular expression -------------------------------------------------------------------------------- [CT]CTGTGGT -------------------------------------------------------------------------------- Time 15.35 secs. ******************************************************************************** ******************************************************************************** MOTIF CACATTCC MEME-5 width = 8 sites = 6 llr = 67 E-value = 5.9e+003 ******************************************************************************** -------------------------------------------------------------------------------- Motif CACATTCC MEME-5 Description -------------------------------------------------------------------------------- Simplified A :a:a:::: pos.-specific C a:a:::aa probability G :::::::: matrix T ::::aa:: bits 2.2 * * ** 1.9 ******** 1.7 ******** 1.5 ******** Relative 1.3 ******** Entropy 1.1 ******** (16.2 bits) 0.9 ******** 0.6 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel CACATTCC consensus sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CACATTCC MEME-5 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr3:71257577-71257657 52 1.29e-05 CTGTTTCAAC CACATTCC AGGGACAAGT chr3:105333306-105333386 14 1.29e-05 CTGCTAACAG CACATTCC AGGGAACACT chr20:30082073-30082153 24 1.29e-05 ccatcatatt cacattcc agccagcagg chr18:33039029-33039109 36 1.29e-05 CAGCCTGAGC CACATTCC TCCTGCCTGA chr11:68899174-68899254 19 1.29e-05 ATGCCTCAGC CACATTCC TGCCTCTAGG chr19:13694065-13694145 69 1.29e-05 CAGCCACAAA CACATTCC AACC -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CACATTCC MEME-5 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr3:71257577-71257657 1.3e-05 51_[+5]_21 chr3:105333306-105333386 1.3e-05 13_[+5]_59 chr20:30082073-30082153 1.3e-05 23_[+5]_49 chr18:33039029-33039109 1.3e-05 35_[+5]_37 chr11:68899174-68899254 1.3e-05 18_[+5]_54 chr19:13694065-13694145 1.3e-05 68_[+5]_4 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CACATTCC MEME-5 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF CACATTCC width=8 seqs=6 chr3:71257577-71257657 ( 52) CACATTCC 1 chr3:105333306-105333386 ( 14) CACATTCC 1 chr20:30082073-30082153 ( 24) CACATTCC 1 chr18:33039029-33039109 ( 36) CACATTCC 1 chr11:68899174-68899254 ( 19) CACATTCC 1 chr19:13694065-13694145 ( 69) CACATTCC 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CACATTCC MEME-5 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 11.229 E= 5.9e+003 -923 216 -923 -923 187 -923 -923 -923 -923 216 -923 -923 187 -923 -923 -923 -923 -923 -923 192 -923 -923 -923 192 -923 216 -923 -923 -923 216 -923 -923 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CACATTCC MEME-5 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 6 E= 5.9e+003 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CACATTCC MEME-5 regular expression -------------------------------------------------------------------------------- CACATTCC -------------------------------------------------------------------------------- Time 18.58 secs. ******************************************************************************** ******************************************************************************** SUMMARY OF MOTIFS ******************************************************************************** -------------------------------------------------------------------------------- Combined block diagrams: non-overlapping sites with p-value < 0.0001 -------------------------------------------------------------------------------- SEQUENCE NAME COMBINED P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr9:101553585-101553665 8.99e-02 80 chr1:234740753-234740833 1.56e-03 12_[+3(3.46e-05)]_60 chr1:214176684-214176764 1.73e-02 9_[+2(6.70e-05)]_63 chr4:151695355-151695435 2.05e-02 80 chr11:85753088-85753168 3.38e-01 80 chr9:96974547-96974627 3.04e-01 80 chr1:95100703-95100783 5.23e-03 15_[+3(5.88e-05)]_57 chr15:67066819-67066899 8.26e-02 39_[+4(5.01e-05)]_33 chr5:95220353-95220433 9.56e-04 70_[+4(6.36e-05)]_2 chr7:132174696-132174776 1.65e-01 80 chr3:16977884-16977964 6.56e-01 80 chr13:44961220-44961300 2.39e-01 80 chr6:152554103-152554183 1.60e-01 80 chr2:30476952-30477032 2.16e-03 80 chr6:74238821-74238901 3.36e-02 80 chr7:5123117-5123197 6.53e-03 80 chr5:158555218-158555298 8.73e-02 80 chr7:127627082-127627162 6.34e-02 80 chr5:10708805-10708885 4.72e-01 80 chr8:23526275-23526355 2.04e-04 28_[+2(3.37e-05)]_44 chr1:51186307-51186387 1.35e-01 59_[+2(6.70e-05)]_13 chr7:24903968-24904048 3.87e-02 80 chr10:63540244-63540324 8.61e-03 80 chr4:103277024-103277104 5.22e-01 80 chr6:150881280-150881360 1.61e-02 22_[+4(1.26e-05)]_50 chr7:66387286-66387366 7.43e-02 80 chr12:65114788-65114868 5.31e-02 23_[+3(9.53e-05)]_14_[+3(9.53e-05)]_\ 27 chr3:137918873-137918953 3.81e-02 80 chr2:37843915-37843995 7.71e-02 80 chr5:178110934-178111014 1.09e-01 80 chr19:13694065-13694145 1.26e-02 68_[+5(1.29e-05)]_4 chr5:111885581-111885661 4.92e-02 80 chr13:44972150-44972230 5.17e-04 33_[+4(2.76e-05)]_39 chr2:68220641-68220721 3.68e-03 28_[+3(4.71e-05)]_44 chrX:55054603-55054683 1.04e-01 80 chr1:206274318-206274398 9.40e-02 80 chrX:119468577-119468657 3.25e-03 80 chr1:48643126-48643206 1.41e-03 39_[+2(1.77e-05)]_33 chr2:27197335-27197415 1.19e-02 10_[+5(8.19e-05)]_53_[+3(6.98e-05)]_\ 1 chr8:2645835-2645915 3.08e-02 80 chr1:53647831-53647911 3.64e-01 80 chr4:25052511-25052591 1.19e-02 80 chr9:7067327-7067407 3.21e-02 80 chr1:26087554-26087634 4.28e-02 80 chr6:109606071-109606151 2.07e-02 80 chr17:33212288-33212368 2.37e-02 60_[+1(8.41e-05)]_12 chrX:107801631-107801711 1.14e-01 21_[+1(8.41e-05)]_51 chr10:82531902-82531982 2.37e-02 80 chr20:37192564-37192644 1.40e-01 80 chr1:214593156-214593236 5.63e-03 80 chr11:68899174-68899254 6.32e-03 18_[+5(1.29e-05)]_54 chr1:45362178-45362258 1.92e-04 12_[+3(9.53e-05)]_18_[+4(9.17e-05)]_\ 34 chrX:39011780-39011860 1.50e-03 14_[+2(6.70e-05)]_58 chrX:109202815-109202895 6.25e-02 80 chr1:230341606-230341686 1.74e-02 9_[+2(3.37e-05)]_63 chr2:48679410-48679490 4.29e-02 11_[+3(3.46e-05)]_61 chr1:70005901-70005981 6.39e-02 80 chr12:60538339-60538419 9.80e-06 47_[+1(2.30e-05)]_25 chr8:106532850-106532930 6.42e-03 80 chr8:49379267-49379347 2.79e-02 80 chr8:21366961-21367041 9.18e-02 32_[+1(8.41e-05)]_40 chr1:156430427-156430507 4.07e-02 12_[+5(8.19e-05)]_60 chr3:148951296-148951376 2.98e-01 80 chr20:35783242-35783322 9.44e-02 80 chr11:47026414-47026494 7.07e-01 80 chr11:82503034-82503114 3.16e-02 80 chr4:95574450-95574530 3.40e-01 80 chr1:95113903-95113983 2.03e-02 24_[+3(5.88e-05)]_48 chr4:160116714-160116794 3.90e-01 80 chr13:99628332-99628412 2.27e-03 80 chr15:93461232-93461312 9.41e-01 80 chr21:32754500-32754580 1.44e-02 80 chr1:222883255-222883335 5.56e-02 80 chr6:19968588-19968668 2.07e-01 80 chr2:217957626-217957706 1.49e-02 80 chr2:42423647-42423727 2.32e-02 33_[+1(8.41e-05)]_39 chr5:168240747-168240827 8.04e-02 8_[+3(3.46e-05)]_64 chr19:16308205-16308285 9.83e-03 80 chr5:131987918-131987998 2.35e-03 55_[+1(2.30e-05)]_17 chr19:54770069-54770149 9.79e-01 80 chrX:134996735-134996815 1.35e-01 80 chr7:148545022-148545102 1.67e-01 25_[+2(6.70e-05)]_47 chr2:15696580-15696660 1.58e-02 60_[+1(8.41e-05)]_12 chr8:67967436-67967516 3.46e-02 80 chr7:37397333-37397413 2.81e-02 80 chr4:79405857-79405937 2.31e-02 11_[+2(6.70e-05)]_61 chr2:178504405-178504485 4.21e-02 80 chr22:40725269-40725349 2.13e-01 80 chr6:21102063-21102143 3.79e-02 56_[+3(9.53e-05)]_16 chr18:33039029-33039109 7.69e-04 14_[+3(6.98e-05)]_13_[+5(1.29e-05)]_\ 37 chr20:5469588-5469668 4.39e-04 11_[+3(4.71e-05)]_15_[+4(6.36e-05)]_\ 38 chrX:37512276-37512356 7.12e-01 80 chr2:178939662-178939742 3.60e-02 80 chr2:46666870-46666950 1.51e-02 80 chr9:86958274-86958354 6.09e-03 80 chr3:156178167-156178247 4.98e-02 80 chr6:20575569-20575649 1.66e-04 43_[+4(6.36e-05)]_29 chrX:122598706-122598786 1.04e-01 80 chr3:10020821-10020901 4.65e-01 80 chr12:21966225-21966305 6.11e-03 51_[+1(2.30e-05)]_21 chr3:133472769-133472849 8.95e-03 80 chr14:31291369-31291449 2.15e-03 28_[+1(2.30e-05)]_44 chr5:169514580-169514660 1.84e-02 80 chr7:117581637-117581717 8.12e-03 24_[+4(2.76e-05)]_48 chr4:99603973-99604053 1.10e-02 24_[+2(3.37e-05)]_48 chr6:164767864-164767944 4.55e-02 80 chr6:15922902-15922982 5.41e-01 80 chr6:140069947-140070027 2.27e-01 59_[+1(8.41e-05)]_13 chr18:67692991-67693071 1.78e-01 80 chr8:56926571-56926651 2.66e-01 80 chr1:168257599-168257679 1.42e-02 80 chr7:119566125-119566205 6.87e-03 80 chr4:10347164-10347244 8.77e-03 44_[+2(6.70e-05)]_28 chr12:28345227-28345307 4.87e-01 80 chr13:39573051-39573131 1.57e-01 80 chrX:49963276-49963356 2.13e-03 31_[+5(8.19e-05)]_41 chr1:209819337-209819417 2.27e-02 80 chr22:30348257-30348337 1.26e-03 6_[+2(3.37e-05)]_7_[+3(3.46e-05)]_\ 51 chr9:125016706-125016786 1.41e-02 80 chr1:204196621-204196701 3.75e-01 80 chr5:89954577-89954657 1.98e-01 80 chr10:75913048-75913128 7.69e-01 80 chr15:31270673-31270753 9.79e-02 37_[+1(4.30e-05)]_35 chr9:130188248-130188328 8.13e-02 80 chr15:50886658-50886738 9.49e-02 80 chr15:57675325-57675405 3.99e-01 80 chr9:114856005-114856085 3.24e-02 19_[+1(2.30e-05)]_53 chr1:101251443-101251523 4.33e-03 8_[+4(2.76e-05)]_8_[+2(6.70e-05)]_\ 48 chr2:160353944-160354024 6.44e-04 50_[+4(1.26e-05)]_22 chr14:75177348-75177428 2.26e-02 80 chr3:32750308-32750388 2.29e-02 7_[+2(8.60e-05)]_65 chr1:246588580-246588660 1.54e-01 80 chr1:95581328-95581408 6.45e-01 80 chr10:17045278-17045358 2.82e-01 80 chr1:179941155-179941235 8.36e-04 28_[+3(5.88e-05)]_7_[+1(4.30e-05)]_\ 29 chr20:9129850-9129930 5.56e-02 80 chr17:33214019-33214099 2.32e-01 80 chr15:64731399-64731479 2.51e-01 80 chr3:151444006-151444086 1.04e-01 80 chr2:64582057-64582137 7.75e-02 80 chr14:55850704-55850784 2.15e-04 60_[+1(2.30e-05)]_12 chr12:89787579-89787659 7.85e-02 80 chr16:50105138-50105218 1.21e-01 80 chr4:81174848-81174928 6.09e-03 65_[+3(6.98e-05)]_7 chr16:21272959-21273039 8.20e-02 80 chr16:8688297-8688377 2.57e-01 80 chr8:96939401-96939481 2.67e-02 80 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5.00e-05 23_[+4(1.26e-05)]_39_[+1(2.30e-05)]_\ 2 chr7:135718340-135718420 9.58e-03 68_[+1(2.30e-05)]_4 chr2:32993554-32993634 2.64e-01 80 chr15:39432297-39432377 2.01e-03 20_[+1(8.41e-05)]_52 chr7:102082193-102082273 4.15e-02 80 chr20:20927143-20927223 7.59e-04 24_[+1(4.30e-05)]_48 chr3:71257577-71257657 1.92e-03 18_[+1(2.30e-05)]_25_[+5(1.29e-05)]_\ 21 chr2:74311079-74311159 1.21e-01 80 chr8:87522864-87522944 6.20e-02 80 chr9:127727085-127727165 1.03e-03 24_[+3(5.88e-05)]_48 chrX:55041562-55041642 1.43e-02 80 chr4:109035778-109035858 3.78e-02 80 chr1:206909005-206909085 1.07e-05 24_[+4(2.76e-05)]_12_[+3(1.10e-05)]_\ 2_[+1(8.41e-05)]_18 chr7:115858315-115858395 6.24e-02 17_[+2(3.37e-05)]_55 chr3:179093055-179093135 1.52e-01 80 chr4:96210548-96210628 2.84e-03 [+2(8.60e-05)]_56_[+3(4.71e-05)]_8 chr20:42639110-42639190 2.40e-02 37_[+1(4.30e-05)]_35 chr20:32007090-32007170 3.10e-01 80 chr10:126406632-12640671 2.02e-02 16_[+3(4.71e-05)]_56 chr3:98302731-98302811 3.06e-02 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******************************************************************************** ******************************************************************************** Stopped because requested number of motifs (5) found. ******************************************************************************** CPU: c22n04.farnam.hpc.yale.internal ********************************************************************************