******************************************************************************** MEME - Motif discovery tool ******************************************************************************** MEME version 5.3.3 (Release date: Sun Feb 7 15:39:52 2021 -0800) For further information on how to interpret these results please access https://meme-suite.org/meme. To get a copy of the MEME Suite software please access https://meme-suite.org. ******************************************************************************** ******************************************************************************** REFERENCE ******************************************************************************** If you use this program in your research, please cite: Timothy L. Bailey and Charles Elkan, "Fitting a mixture model by expectation maximization to discover motifs in biopolymers", Proceedings of the Second International Conference on Intelligent Systems for Molecular Biology, pp. 28-36, AAAI Press, Menlo Park, California, 1994. ******************************************************************************** ******************************************************************************** TRAINING SET ******************************************************************************** PRIMARY SEQUENCES= ../result/final_prediction/K562/fasta/RankLinear0.6_40/TBP.fasta CONTROL SEQUENCES= --none-- ALPHABET= ACGT Sequence name Weight Length Sequence name Weight Length ------------- ------ ------ ------------- ------ ------ chr14:21098656-21098736 1.0000 80 chr17:8022401-8022481 1.0000 80 chr16:3232692-3232772 1.0000 80 chr14:21099363-21099443 1.0000 80 chr17:8029000-8029080 1.0000 80 chr17:19411429-19411509 1.0000 80 chr16:3230611-3230691 1.0000 80 chr6:27688963-27689043 1.0000 80 chr6:27302824-27302904 1.0000 80 chr6:28574872-28574952 1.0000 80 chr14:21121338-21121418 1.0000 80 chr6:27471448-27471528 1.0000 80 chr6:28616038-28616118 1.0000 80 chr14:21149788-21149868 1.0000 80 chr7:149052823-149052903 1.0000 80 chr6:28611161-28611241 1.0000 80 chr6:26305774-26305854 1.0000 80 chr16:71460330-71460410 1.0000 80 chr17:8042829-8042909 1.0000 80 chr14:21077556-21077636 1.0000 80 chr6:27694408-27694488 1.0000 80 chr14:21151360-21151440 1.0000 80 chr16:3221984-3222064 1.0000 80 chr6:27177565-27177645 1.0000 80 chr6:28694876-28694956 1.0000 80 chr1:147825654-147825734 1.0000 80 chr17:37017998-37018078 1.0000 80 chr19:12750989-12751069 1.0000 80 chr7:149028153-149028233 1.0000 80 chr1:222638281-222638361 1.0000 80 chr14:21152109-21152189 1.0000 80 chr6:27529896-27529976 1.0000 80 chr14:21101102-21101182 1.0000 80 chr6:26575731-26575811 1.0000 80 chr16:3225627-3225707 1.0000 80 chr16:3241428-3241508 1.0000 80 chr16:3239563-3239643 1.0000 80 chr16:3246100-3246180 1.0000 80 chr7:149404696-149404776 1.0000 80 chr17:8089593-8089673 1.0000 80 chr13:31248164-31248244 1.0000 80 chr14:21131442-21131522 1.0000 80 chr6:27543791-27543871 1.0000 80 chr14:21125706-21125786 1.0000 80 chr6:27559651-27559731 1.0000 80 chr8:67026328-67026408 1.0000 80 chr21:18827160-18827240 1.0000 80 chr6:27551263-27551343 1.0000 80 chr6:26331726-26331806 1.0000 80 chr13:95201957-95202037 1.0000 80 chrX:18693084-18693164 1.0000 80 chr17:8023008-8023088 1.0000 80 chr14:89445377-89445457 1.0000 80 chr13:41634934-41635014 1.0000 80 chr11:61266567-61266647 1.0000 80 chr10:23286146-23286226 1.0000 80 chr17:8125613-8125693 1.0000 80 chr16:22309909-22309989 1.0000 80 chr14:58706663-58706743 1.0000 80 chr19:4724698-4724778 1.0000 80 chr16:14379681-14379761 1.0000 80 chr19:5352442-5352522 1.0000 80 chr17:8124240-8124320 1.0000 80 chr6:27499917-27499997 1.0000 80 chr14:21078223-21078303 1.0000 80 chr14:21093463-21093543 1.0000 80 chr1:161501873-161501953 1.0000 80 chr16:3207465-3207545 1.0000 80 chr11:1372879-1372959 1.0000 80 chr7:149344108-149344188 1.0000 80 chr22:37589964-37590044 1.0000 80 chr1:36850241-36850321 1.0000 80 chr17:8124801-8124881 1.0000 80 chr1:145396954-145397034 1.0000 80 chr6:27261644-27261724 1.0000 80 chr5:135416273-135416353 1.0000 80 chr10:126107463-12610754 1.0000 80 chr2:30454356-30454436 1.0000 80 chr6:26319386-26319466 1.0000 80 chr6:27759189-27759269 1.0000 80 chr3:169489952-169490032 1.0000 80 chr15:45493266-45493346 1.0000 80 chr6:28626031-28626111 1.0000 80 chr6:26299879-26299959 1.0000 80 chrX:73072521-73072601 1.0000 80 chr6:26595041-26595121 1.0000 80 chr6:27586079-27586159 1.0000 80 chr6:26555432-26555512 1.0000 80 chr17:37310049-37310129 1.0000 80 chr6:28956715-28956795 1.0000 80 chr5:180600576-180600656 1.0000 80 chr17:73029932-73030012 1.0000 80 chr6:28703265-28703345 1.0000 80 chr2:131094761-131094841 1.0000 80 chr1:161390616-161390696 1.0000 80 chr6:28918740-28918820 1.0000 80 chr17:8042260-8042340 1.0000 80 chr6:28791147-28791227 1.0000 80 chr15:79152878-79152958 1.0000 80 chr11:2398498-2398578 1.0000 80 chr1:71513488-71513568 1.0000 80 chr15:26327437-26327517 1.0000 80 chr14:102783353-10278343 1.0000 80 chr17:36908094-36908174 1.0000 80 chr6:27447385-27447465 1.0000 80 chr5:180614631-180614711 1.0000 80 chr2:11691760-11691840 1.0000 80 chr6:28687423-28687503 1.0000 80 chr14:102176570-10217665 1.0000 80 chr6:27652530-27652610 1.0000 80 chr1:68005120-68005200 1.0000 80 chr9:133407165-133407245 1.0000 80 chr6:28779909-28779989 1.0000 80 chr18:9014280-9014360 1.0000 80 chr1:207779146-207779226 1.0000 80 chr11:59319216-59319296 1.0000 80 chr20:60641060-60641140 1.0000 80 chr6:27205389-27205469 1.0000 80 chr17:8126214-8126294 1.0000 80 chrX:47662137-47662217 1.0000 80 chr6:26312035-26312115 1.0000 80 chr9:14433996-14434076 1.0000 80 chr6:26312796-26312876 1.0000 80 chr6:27129983-27130063 1.0000 80 chr16:3243873-3243953 1.0000 80 chr17:37025601-37025681 1.0000 80 chr6:28912285-28912365 1.0000 80 chr6:27515589-27515669 1.0000 80 chrX:71401476-71401556 1.0000 80 chr17:8024225-8024305 1.0000 80 chr6:27618758-27618838 1.0000 80 chr12:113552404-11355248 1.0000 80 chr6:26553664-26553744 1.0000 80 chr1:173890156-173890236 1.0000 80 chr17:77813206-77813286 1.0000 80 chr1:28672827-28672907 1.0000 80 chr11:66115520-66115600 1.0000 80 chr1:147752739-147752819 1.0000 80 chr6:28757607-28757687 1.0000 80 chr6:27263148-27263228 1.0000 80 chr6:27248098-27248178 1.0000 80 chr6:27065022-27065102 1.0000 80 chr17:10694465-10694545 1.0000 80 chr14:23120247-23120327 1.0000 80 chr5:132002078-132002158 1.0000 80 chr8:67025534-67025614 1.0000 80 chr16:70813004-70813084 1.0000 80 chr2:183859007-183859087 1.0000 80 chr7:149007219-149007299 1.0000 80 chr2:47562378-47562458 1.0000 80 chr12:125406367-12540644 1.0000 80 chr1:161397923-161398003 1.0000 80 chr6:26311467-26311547 1.0000 80 chr6:27636314-27636394 1.0000 80 chr6:27509623-27509703 1.0000 80 chr17:8129613-8129693 1.0000 80 chr11:122430591-12243067 1.0000 80 chr6:28775667-28775747 1.0000 80 chr17:8090249-8090329 1.0000 80 chr16:3208860-3208940 1.0000 80 chr6:64282342-64282422 1.0000 80 chr14:103989145-10398922 1.0000 80 chr5:180634680-180634760 1.0000 80 chr16:70823335-70823415 1.0000 80 chr6:28911471-28911551 1.0000 80 chr1:147781084-147781164 1.0000 80 chr17:72744726-72744806 1.0000 80 chr6:27638398-27638478 1.0000 80 chr2:157257202-157257282 1.0000 80 chr16:3200614-3200694 1.0000 80 chr17:29877029-29877109 1.0000 80 chr14:21081611-21081691 1.0000 80 chr17:37310805-37310885 1.0000 80 chr11:59323833-59323913 1.0000 80 chr17:76356137-76356217 1.0000 80 chr6:28505338-28505418 1.0000 80 chr14:20937523-20937603 1.0000 80 chr1:161493695-161493775 1.0000 80 chr11:120107274-12010735 1.0000 80 chr9:131580722-131580802 1.0000 80 chr12:98897213-98897293 1.0000 80 chr6:134495963-134496043 1.0000 80 chr7:2913689-2913769 1.0000 80 chr17:8023695-8023775 1.0000 80 chr1:161591430-161591510 1.0000 80 chr21:36260953-36261033 1.0000 80 chr16:87417686-87417766 1.0000 80 chr1:147737426-147737506 1.0000 80 chr1:228743436-228743516 1.0000 80 chr16:22207106-22207186 1.0000 80 chr6:28456837-28456917 1.0000 80 chr10:3214938-3215018 1.0000 80 chr6:27059456-27059536 1.0000 80 chr17:79008928-79009008 1.0000 80 chr2:239148640-239148720 1.0000 80 chr7:73761886-73761966 1.0000 80 chr14:21137368-21137448 1.0000 80 chr19:893358-893438 1.0000 80 chr20:57464162-57464242 1.0000 80 chr6:26577276-26577356 1.0000 80 chr2:108972727-108972807 1.0000 80 chr5:60628019-60628099 1.0000 80 chr14:34420235-34420315 1.0000 80 chr1:145397919-145397999 1.0000 80 chr6:161695190-161695270 1.0000 80 chr6:27763701-27763781 1.0000 80 chr6:27745600-27745680 1.0000 80 chr11:129939743-12993982 1.0000 80 chr16:11350019-11350099 1.0000 80 chr16:686792-686872 1.0000 80 chr19:14640377-14640457 1.0000 80 chr19:5434703-5434783 1.0000 80 chr2:30884097-30884177 1.0000 80 chr6:27181693-27181773 1.0000 80 chr3:49449593-49449673 1.0000 80 chr12:104850721-10485080 1.0000 80 chr10:105127697-10512777 1.0000 80 chr5:180615935-180616015 1.0000 80 chr6:27835339-27835419 1.0000 80 chr18:57567181-57567261 1.0000 80 chr6:27265702-27265782 1.0000 80 chr6:28688220-28688300 1.0000 80 chr17:73030581-73030661 1.0000 80 chr11:65222718-65222798 1.0000 80 chrX:151143102-151143182 1.0000 80 chr3:112360143-112360223 1.0000 80 chr2:191745500-191745580 1.0000 80 chr12:96429728-96429808 1.0000 80 chr20:52369833-52369913 1.0000 80 chr11:117997186-11799726 1.0000 80 chr6:28921098-28921178 1.0000 80 chr16:89989693-89989773 1.0000 80 chr4:1714018-1714098 1.0000 80 chr10:70320051-70320131 1.0000 80 chr6:28710781-28710861 1.0000 80 chr12:125412483-12541256 1.0000 80 chr7:149388326-149388406 1.0000 80 chr5:78884590-78884670 1.0000 80 chr2:96217212-96217292 1.0000 80 chr5:180633801-180633881 1.0000 80 chr7:25894895-25894975 1.0000 80 chr11:64937647-64937727 1.0000 80 chr2:20646789-20646869 1.0000 80 chr1:32801808-32801888 1.0000 80 chr20:62152079-62152159 1.0000 80 chr19:4969054-4969134 1.0000 80 chr3:129118804-129118884 1.0000 80 chr6:28849103-28849183 1.0000 80 chr6:28697025-28697105 1.0000 80 chr6:28442384-28442464 1.0000 80 ******************************************************************************** ******************************************************************************** COMMAND LINE SUMMARY ******************************************************************************** This information can also be useful in the event you wish to report a problem with the MEME software. command: meme -oc ../result/final_prediction/K562/inference_raw/MEME/RankLinear0.6_40_TBP/ -dna -nmotifs 5 -w 8 -maxsize 250000 -nostatus ../result/final_prediction/K562/fasta/RankLinear0.6_40/TBP.fasta model: mod= zoops nmotifs= 5 evt= inf objective function: em= E-value of product of p-values starts= E-value of product of p-values strands: + width: minw= 8 maxw= 8 nsites: minsites= 2 maxsites= 250 wnsites= 0.8 theta: spmap= uni spfuzz= 0.5 em: prior= dirichlet b= 0.01 maxiter= 50 distance= 1e-05 trim: wg= 11 ws= 1 endgaps= yes data: n= 20000 N= 250 sample: seed= 0 hsfrac= 0 searchsize= 20000 norand= no csites= 1000 Letter frequencies in dataset: A 0.245 C 0.252 G 0.262 T 0.241 Background letter frequencies (from file dataset with add-one prior applied): A 0.245 C 0.252 G 0.262 T 0.241 Background model order: 0 ******************************************************************************** ******************************************************************************** MOTIF TAGCTCAG MEME-1 width = 8 sites = 23 llr = 235 E-value = 6.3e-013 ******************************************************************************** -------------------------------------------------------------------------------- Motif TAGCTCAG MEME-1 Description -------------------------------------------------------------------------------- Simplified A :9::::a: pos.-specific C :::a:a:: probability G ::a::::a matrix T a:::a::: bits 2.1 * *** 1.8 * *** 1.6 * ****** 1.4 ******** Relative 1.2 ******** Entropy 1.0 ******** (14.7 bits) 0.8 ******** 0.6 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel TAGCTCAG consensus sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TAGCTCAG MEME-1 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr6:26577276-26577356 63 1.52e-05 TGTccttcga tagctcag ttggtagagc chr11:122430591-12243067 71 1.52e-05 gtagcctgga tagctcag tt chr6:27636314-27636394 55 1.52e-05 TGTggccggt tagctcag tcggctagag chr7:149007219-149007299 69 1.52e-05 GCAgggggca tagctcag tggt chr6:28687423-28687503 65 1.52e-05 AACgggggtg tagctcag tggtagag chr15:79152878-79152958 33 1.52e-05 ACTgcccggc tagctcag tcggtagagc chr6:28918740-28918820 73 1.52e-05 GGAgcccgga tagctcag chr6:27586079-27586159 63 1.52e-05 CGTggccctg tagctcag cggttggagc chr6:26595041-26595121 68 1.52e-05 CATccttcga tagctcag ctggt chr6:27261644-27261724 34 1.52e-05 GTCggccggt tagctcag ttggttagag chr6:27543791-27543871 62 1.52e-05 AGAAcctggg tagctcag taggtagaac chr7:149404696-149404776 71 1.52e-05 TCAgggggta tagctcag gg chr16:3246100-3246180 60 1.52e-05 TATgcccagc tagctcag ccggtagagc chr16:3225627-3225707 72 1.52e-05 GTCgcccggc tagctcag t chr1:222638281-222638361 73 1.52e-05 GTGggctcca tagctcag chr6:28611161-28611241 68 1.52e-05 TGTggggatg tagctcag tggta chr14:21149788-21149868 68 1.52e-05 TGAggcccta tagctcag gggtt chr6:28574872-28574952 68 1.52e-05 GTTgggggtg tagctcag tggta chr6:27263148-27263228 51 5.79e-05 TAGGAAATGC TAGTTCAG CTTCAggttc chr14:89445377-89445457 72 5.79e-05 CATggggaat tagctcaa g chr6:28694876-28694956 43 5.79e-05 ccaaccgagc tatctcag cTTACTGTAG chr10:105127697-10512777 35 8.98e-05 CGGCGCGAGG TGGCTCAG CCGCAAGATG chr17:77813206-77813286 20 8.98e-05 CGGCTCGCGC TCGCTCAG ACAACTGAGC -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TAGCTCAG MEME-1 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr6:26577276-26577356 1.5e-05 62_[+1]_10 chr11:122430591-12243067 1.5e-05 70_[+1]_2 chr6:27636314-27636394 1.5e-05 54_[+1]_18 chr7:149007219-149007299 1.5e-05 68_[+1]_4 chr6:28687423-28687503 1.5e-05 64_[+1]_8 chr15:79152878-79152958 1.5e-05 32_[+1]_40 chr6:28918740-28918820 1.5e-05 72_[+1] chr6:27586079-27586159 1.5e-05 62_[+1]_10 chr6:26595041-26595121 1.5e-05 67_[+1]_5 chr6:27261644-27261724 1.5e-05 33_[+1]_39 chr6:27543791-27543871 1.5e-05 61_[+1]_11 chr7:149404696-149404776 1.5e-05 70_[+1]_2 chr16:3246100-3246180 1.5e-05 59_[+1]_13 chr16:3225627-3225707 1.5e-05 71_[+1]_1 chr1:222638281-222638361 1.5e-05 72_[+1] chr6:28611161-28611241 1.5e-05 67_[+1]_5 chr14:21149788-21149868 1.5e-05 67_[+1]_5 chr6:28574872-28574952 1.5e-05 67_[+1]_5 chr6:27263148-27263228 5.8e-05 50_[+1]_22 chr14:89445377-89445457 5.8e-05 71_[+1]_1 chr6:28694876-28694956 5.8e-05 42_[+1]_30 chr10:105127697-10512777 9e-05 34_[+1]_38 chr17:77813206-77813286 9e-05 19_[+1]_53 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TAGCTCAG MEME-1 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF TAGCTCAG width=8 seqs=23 chr6:26577276-26577356 ( 63) TAGCTCAG 1 chr11:122430591-12243067 ( 71) TAGCTCAG 1 chr6:27636314-27636394 ( 55) TAGCTCAG 1 chr7:149007219-149007299 ( 69) TAGCTCAG 1 chr6:28687423-28687503 ( 65) TAGCTCAG 1 chr15:79152878-79152958 ( 33) TAGCTCAG 1 chr6:28918740-28918820 ( 73) TAGCTCAG 1 chr6:27586079-27586159 ( 63) TAGCTCAG 1 chr6:26595041-26595121 ( 68) TAGCTCAG 1 chr6:27261644-27261724 ( 34) TAGCTCAG 1 chr6:27543791-27543871 ( 62) TAGCTCAG 1 chr7:149404696-149404776 ( 71) TAGCTCAG 1 chr16:3246100-3246180 ( 60) TAGCTCAG 1 chr16:3225627-3225707 ( 72) TAGCTCAG 1 chr1:222638281-222638361 ( 73) TAGCTCAG 1 chr6:28611161-28611241 ( 68) TAGCTCAG 1 chr14:21149788-21149868 ( 68) TAGCTCAG 1 chr6:28574872-28574952 ( 68) TAGCTCAG 1 chr6:27263148-27263228 ( 51) TAGTTCAG 1 chr14:89445377-89445457 ( 72) TAGCTCAA 1 chr6:28694876-28694956 ( 43) TATCTCAG 1 chr10:105127697-10512777 ( 35) TGGCTCAG 1 chr17:77813206-77813286 ( 20) TCGCTCAG 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TAGCTCAG MEME-1 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 10.0332 E= 6.3e-013 -1117 -1117 -1117 205 190 -253 -259 -1117 -1117 -1117 187 -247 -1117 193 -1117 -247 -1117 -1117 -1117 205 -1117 199 -1117 -1117 203 -1117 -1117 -1117 -249 -1117 187 -1117 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TAGCTCAG MEME-1 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 23 E= 6.3e-013 0.000000 0.000000 0.000000 1.000000 0.913043 0.043478 0.043478 0.000000 0.000000 0.000000 0.956522 0.043478 0.000000 0.956522 0.000000 0.043478 0.000000 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.043478 0.000000 0.956522 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TAGCTCAG MEME-1 regular expression -------------------------------------------------------------------------------- TAGCTCAG -------------------------------------------------------------------------------- Time 4.97 secs. ******************************************************************************** ******************************************************************************** MOTIF CTGAGCTA MEME-2 width = 8 sites = 14 llr = 145 E-value = 8.5e-002 ******************************************************************************** -------------------------------------------------------------------------------- Motif CTGAGCTA MEME-2 Description -------------------------------------------------------------------------------- Simplified A ::1a1::a pos.-specific C a::::a1: probability G ::9:9::: matrix T :a::::9: bits 2.1 ** * * * 1.8 ** * * * 1.6 ******** 1.4 ******** Relative 1.2 ******** Entropy 1.0 ******** (14.9 bits) 0.8 ******** 0.6 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel CTGAGCTA consensus sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTGAGCTA MEME-2 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr7:149388326-149388406 3 1.52e-05 cc ctgagcta tatccccATG chr6:28775667-28775747 1 1.52e-05 . ctgagcta tctcggcCAC chr17:37025601-37025681 1 1.52e-05 . ctgagcta tacccccGCG chr6:27205389-27205469 20 1.52e-05 ctctaaccaa ctgagcta accggccACC chr6:28791147-28791227 5 1.52e-05 ccaa ctgagcta tttcggcTAC chr6:28626031-28626111 40 1.52e-05 cgctctacca ctgagcta catccccACC chr14:58706663-58706743 8 1.52e-05 ctaccga ctgagcta gccgggcGCC chr13:95201957-95202037 5 1.52e-05 ccaa ctgagcta tttcggcACG chr6:27302824-27302904 3 1.52e-05 ga ctgagcta cccaggcTCC chr16:3230611-3230691 2 1.52e-05 a ctgagcta gccgggcTTC chr14:21099363-21099443 14 1.52e-05 gctctaaccc ctgagcta tggagccGCC chr11:120107274-12010735 16 4.36e-05 TTTTCCTCTC CTAAGCTA AACAGGGACA chrX:47662137-47662217 27 4.36e-05 atcttagctc ctgaacta TTgcacaagg chr22:37589964-37590044 13 5.95e-05 gccttagcta ctgagcca cggcactaga -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTGAGCTA MEME-2 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr7:149388326-149388406 1.5e-05 2_[+2]_70 chr6:28775667-28775747 1.5e-05 [+2]_72 chr17:37025601-37025681 1.5e-05 [+2]_72 chr6:27205389-27205469 1.5e-05 19_[+2]_53 chr6:28791147-28791227 1.5e-05 4_[+2]_68 chr6:28626031-28626111 1.5e-05 39_[+2]_33 chr14:58706663-58706743 1.5e-05 7_[+2]_65 chr13:95201957-95202037 1.5e-05 4_[+2]_68 chr6:27302824-27302904 1.5e-05 2_[+2]_70 chr16:3230611-3230691 1.5e-05 1_[+2]_71 chr14:21099363-21099443 1.5e-05 13_[+2]_59 chr11:120107274-12010735 4.4e-05 15_[+2]_57 chrX:47662137-47662217 4.4e-05 26_[+2]_46 chr22:37589964-37590044 6e-05 12_[+2]_60 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTGAGCTA MEME-2 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF CTGAGCTA width=8 seqs=14 chr7:149388326-149388406 ( 3) CTGAGCTA 1 chr6:28775667-28775747 ( 1) CTGAGCTA 1 chr17:37025601-37025681 ( 1) CTGAGCTA 1 chr6:27205389-27205469 ( 20) CTGAGCTA 1 chr6:28791147-28791227 ( 5) CTGAGCTA 1 chr6:28626031-28626111 ( 40) CTGAGCTA 1 chr14:58706663-58706743 ( 8) CTGAGCTA 1 chr13:95201957-95202037 ( 5) CTGAGCTA 1 chr6:27302824-27302904 ( 3) CTGAGCTA 1 chr16:3230611-3230691 ( 2) CTGAGCTA 1 chr14:21099363-21099443 ( 14) CTGAGCTA 1 chr11:120107274-12010735 ( 16) CTAAGCTA 1 chrX:47662137-47662217 ( 27) CTGAACTA 1 chr22:37589964-37590044 ( 13) CTGAGCCA 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTGAGCTA MEME-2 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 10.1909 E= 8.5e-002 -1045 199 -1045 -1045 -1045 -1045 -1045 205 -178 -1045 182 -1045 203 -1045 -1045 -1045 -178 -1045 182 -1045 -1045 199 -1045 -1045 -1045 -181 -1045 194 203 -1045 -1045 -1045 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTGAGCTA MEME-2 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 14 E= 8.5e-002 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.071429 0.000000 0.928571 0.000000 1.000000 0.000000 0.000000 0.000000 0.071429 0.000000 0.928571 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.071429 0.000000 0.928571 1.000000 0.000000 0.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTGAGCTA MEME-2 regular expression -------------------------------------------------------------------------------- CTGAGCTA -------------------------------------------------------------------------------- Time 8.77 secs. ******************************************************************************** ******************************************************************************** MOTIF CTCGTTRG MEME-3 width = 8 sites = 17 llr = 162 E-value = 2.7e+001 ******************************************************************************** -------------------------------------------------------------------------------- Motif CTCGTTRG MEME-3 Description -------------------------------------------------------------------------------- Simplified A ::::::5: pos.-specific C a:a2:::: probability G :::6::5a matrix T :a:1aa:: bits 2.1 *** ** 1.8 *** ** * 1.6 *** ** * 1.4 *** ** * Relative 1.2 *** ** * Entropy 1.0 *** **** (13.8 bits) 0.8 *** **** 0.6 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel CTCGTTAG consensus C G sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTCGTTRG MEME-3 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr12:96429728-96429808 73 1.49e-05 CGTGCGGTtc ctcgttag chr12:98897213-98897293 70 1.49e-05 CTAACGACtc ctcgttag tat chr6:27447385-27447465 70 1.49e-05 ACGTCAATtc ctcgttag tat chr1:161501873-161501953 44 1.49e-05 CCCGGTTGTA ctcgttag tatagtggtg chr6:27059456-27059536 67 3.09e-05 TTCTAAGTgg ctcgttgg tctagg chr16:3208860-3208940 65 3.09e-05 GTCGTCCTgg ctcgttgg tctagggg chr6:26555432-26555512 68 3.09e-05 GCTCAGGCgg ctcgttgg tctag chr16:3239563-3239643 73 3.09e-05 AATCGTGTgg ctcgttgg chr14:21101102-21101182 65 3.09e-05 CCAGTTCTgg ctcgttgg tctagtgg chr14:21152109-21152189 68 3.09e-05 GCTACAGTgg ctcgttgg tctag chr16:3221984-3222064 67 3.09e-05 GCACGGGAgg ctcgttgg tctagg chr6:28688220-28688300 16 4.53e-05 TGAAAAGGAT CTCCTTAG ACACTTAACC chr6:28912285-28912365 69 4.53e-05 AGACAGTTgc ctccttag cgca chr6:27302824-27302904 17 4.53e-05 gctacccagg cTCCTTAG GGAACTGTTT chr17:37025601-37025681 41 6.07e-05 CTGGAGGCGG CTCCTTGG GTGCTAAGCA chr6:28456837-28456917 18 7.44e-05 CGCGGAAGCA CTCTTTAG AGGTGAATCT chr1:173890156-173890236 16 7.44e-05 gttgtcatgt ctctttag tcttctgcag -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTCGTTRG MEME-3 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr12:96429728-96429808 1.5e-05 72_[+3] chr12:98897213-98897293 1.5e-05 69_[+3]_3 chr6:27447385-27447465 1.5e-05 69_[+3]_3 chr1:161501873-161501953 1.5e-05 43_[+3]_29 chr6:27059456-27059536 3.1e-05 66_[+3]_6 chr16:3208860-3208940 3.1e-05 64_[+3]_8 chr6:26555432-26555512 3.1e-05 67_[+3]_5 chr16:3239563-3239643 3.1e-05 72_[+3] chr14:21101102-21101182 3.1e-05 64_[+3]_8 chr14:21152109-21152189 3.1e-05 67_[+3]_5 chr16:3221984-3222064 3.1e-05 66_[+3]_6 chr6:28688220-28688300 4.5e-05 15_[+3]_57 chr6:28912285-28912365 4.5e-05 68_[+3]_4 chr6:27302824-27302904 4.5e-05 16_[+3]_56 chr17:37025601-37025681 6.1e-05 40_[+3]_32 chr6:28456837-28456917 7.4e-05 17_[+3]_55 chr1:173890156-173890236 7.4e-05 15_[+3]_57 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTCGTTRG MEME-3 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF CTCGTTRG width=8 seqs=17 chr12:96429728-96429808 ( 73) CTCGTTAG 1 chr12:98897213-98897293 ( 70) CTCGTTAG 1 chr6:27447385-27447465 ( 70) CTCGTTAG 1 chr1:161501873-161501953 ( 44) CTCGTTAG 1 chr6:27059456-27059536 ( 67) CTCGTTGG 1 chr16:3208860-3208940 ( 65) CTCGTTGG 1 chr6:26555432-26555512 ( 68) CTCGTTGG 1 chr16:3239563-3239643 ( 73) CTCGTTGG 1 chr14:21101102-21101182 ( 65) CTCGTTGG 1 chr14:21152109-21152189 ( 68) CTCGTTGG 1 chr16:3221984-3222064 ( 67) CTCGTTGG 1 chr6:28688220-28688300 ( 16) CTCCTTAG 1 chr6:28912285-28912365 ( 69) CTCCTTAG 1 chr6:27302824-27302904 ( 17) CTCCTTAG 1 chr17:37025601-37025681 ( 41) CTCCTTGG 1 chr6:28456837-28456917 ( 18) CTCTTTAG 1 chr1:173890156-173890236 ( 16) CTCTTTAG 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTCGTTRG MEME-3 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 10.1364 E= 2.7e+001 -1073 199 -1073 -1073 -1073 -1073 -1073 205 -1073 199 -1073 -1073 -1073 -10 130 -103 -1073 -1073 -1073 205 -1073 -1073 -1073 205 111 -1073 84 -1073 -1073 -1073 193 -1073 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTCGTTRG MEME-3 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 17 E= 2.7e+001 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.235294 0.647059 0.117647 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.529412 0.000000 0.470588 0.000000 0.000000 0.000000 1.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTCGTTRG MEME-3 regular expression -------------------------------------------------------------------------------- CTC[GC]TT[AG]G -------------------------------------------------------------------------------- Time 12.56 secs. ******************************************************************************** ******************************************************************************** MOTIF HTWTAARM MEME-4 width = 8 sites = 43 llr = 333 E-value = 1.1e+002 ******************************************************************************** -------------------------------------------------------------------------------- Motif HTWTAARM MEME-4 Description -------------------------------------------------------------------------------- Simplified A 3:6:aa54 pos.-specific C 3::::::4 probability G ::::::5: matrix T 4a4a:::2 bits 2.1 * *** 1.8 * *** 1.6 * *** 1.4 * *** Relative 1.2 * *** Entropy 1.0 ****** (11.2 bits) 0.8 ****** 0.6 ******* 0.4 ******** 0.2 ******** 0.0 -------- Multilevel TTATAAAA consensus A T GC sequence C -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif HTWTAARM MEME-4 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr6:134495963-134496043 62 1.24e-05 GCGCTCGGCC TTATAAAA AAGGCACCGC chr6:26311467-26311547 54 1.24e-05 TTTCATGAAT TTATAAAA ATACTGATTA chr6:27694408-27694488 27 1.24e-05 GTGtaaattt ttataaaa taataaatta chr19:5434703-5434783 70 2.56e-05 cccagaccac ttataaga cat chr2:108972727-108972807 43 2.56e-05 taagtgccct ttataaga atcaacaagt chr6:28505338-28505418 62 2.56e-05 cgcgcggtac ttataaga cagtgcacct chr6:28791147-28791227 55 3.81e-05 TTTCTTCAAA ATATAAAA ACTGCAATTT chr3:49449593-49449673 20 7.72e-05 AACTCCGGGG CTATAAAA GACCTGGTTG chr19:4969054-4969134 42 1.17e-04 GCGCGCGGCC TTATAAGC CCCCCCGCGA chr16:89989693-89989773 26 1.17e-04 GGGGCCGCGG CTATAAGA GCGCGCGGCC chr6:27205389-27205469 60 1.17e-04 GTTCTTTCAA TTTTAAAA AAGCAAAATG chr1:68005120-68005200 26 1.17e-04 gaattggtct ttttaaaa gcttctagga chr6:28611161-28611241 22 1.17e-04 TACAGTATAT TTTTAAAA ACTTTTTTTG chr17:8022401-8022481 41 1.17e-04 GAGAACCCTC TTATAAGC AAAAAGTAAA chr6:26319386-26319466 36 1.43e-04 TCCATTTTCC TTTTAAGA TAAGTATCTA chr1:222638281-222638361 9 1.43e-04 GGACCGCC ATATAAAC CAATGTTGTT chr6:28697025-28697105 37 1.82e-04 GATATTTTAT ATATAAGC CAACAGAACT chr6:28849103-28849183 37 1.82e-04 TTTGTGTGCT ATATAAGC ATCTGTCTTT chr1:32801808-32801888 52 1.82e-04 AGCTGCCTAT ATATAAGC GCCCGGAGCT chr11:64937647-64937727 29 1.82e-04 CCCTCAGGCT ATATAAGC GCACTCGCGG chr6:27835339-27835419 53 1.82e-04 CCCCGGGCTT ATATAAGC CGGCGCTGCC chr6:27059456-27059536 40 1.82e-04 CCTACAGTAA ATATAAGC AAAAGCCATT chr14:20937523-20937603 13 1.82e-04 AGGGCAAGGG ATATAAGC CAGAGCCTAG chr6:26555432-26555512 6 1.82e-04 CGTAC ATTTAAAA AAAAAGAAAT chr7:149344108-149344188 36 1.82e-04 CTACTAACCA CTATAAAC CTGTATGGCC chr10:23286146-23286226 15 1.82e-04 CTTTAAACTG ATTTAAAA ATAAGGACAG chr16:11350019-11350099 65 2.35e-04 TGCGCCAGTC TTTTAAAC CGGCTCGG chr6:27763701-27763781 13 2.35e-04 atggggccAC CTATAAGC CTGCTTATGA chr19:893358-893438 49 2.35e-04 TCTCTAGGTC ATTTAAGA GAAGTCGGCC chr6:27636314-27636394 23 2.35e-04 ATATGGTTTC CTTTAAAA CAGCAGCGCA chr2:183859007-183859087 59 2.35e-04 gattccccag ctttaaaa tagactacct chrX:73072521-73072601 52 2.62e-04 AATTGCAGCG CTTTAAGA ACTGAAGGGG chr6:28921098-28921178 66 2.87e-04 TTTTTACCTT ATTTAAAC ATTTTTG chr6:27129983-27130063 30 2.87e-04 TACAAAAATG TTATAAAT ACGATATATC chr6:28574872-28574952 19 2.87e-04 GAAATACTGA TTATAAAT CATGAAAGAA chr6:28626031-28626111 73 3.26e-04 AAACGTTCGT CTTTAAAC chr17:8029000-8029080 53 3.53e-04 CCCGCAGAAT CTTTAAGC CGCgcattgg chr20:62152079-62152159 11 3.79e-04 GCCCCCGCGC ATATAAGT GGGCGCGTCC chr2:30454356-30454436 12 3.79e-04 GCCCCCGCCC CTATAAAT ACGGCTTCCC chr11:2398498-2398578 11 4.04e-04 cCGCGGCGCC CTATAAGT ACTGCGGAGC chr6:28442384-28442464 58 4.17e-04 CTATTCCTGC TTTTAAGT AAAAGATTCT chr2:20646789-20646869 13 4.54e-04 TGGCCGGACT CTTTAAAT AGCGGGCGCT chr19:4724698-4724778 39 4.54e-04 CGTCAGGGTT CTTTAAAT TCTCCTATAG -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif HTWTAARM MEME-4 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr6:134495963-134496043 1.2e-05 61_[+4]_11 chr6:26311467-26311547 1.2e-05 53_[+4]_19 chr6:27694408-27694488 1.2e-05 26_[+4]_46 chr19:5434703-5434783 2.6e-05 69_[+4]_3 chr2:108972727-108972807 2.6e-05 42_[+4]_30 chr6:28505338-28505418 2.6e-05 61_[+4]_11 chr6:28791147-28791227 3.8e-05 54_[+4]_18 chr3:49449593-49449673 7.7e-05 19_[+4]_53 chr19:4969054-4969134 0.00012 41_[+4]_31 chr16:89989693-89989773 0.00012 25_[+4]_47 chr6:27205389-27205469 0.00012 59_[+4]_13 chr1:68005120-68005200 0.00012 25_[+4]_47 chr6:28611161-28611241 0.00012 21_[+4]_51 chr17:8022401-8022481 0.00012 40_[+4]_32 chr6:26319386-26319466 0.00014 35_[+4]_37 chr1:222638281-222638361 0.00014 8_[+4]_64 chr6:28697025-28697105 0.00018 36_[+4]_36 chr6:28849103-28849183 0.00018 36_[+4]_36 chr1:32801808-32801888 0.00018 51_[+4]_21 chr11:64937647-64937727 0.00018 28_[+4]_44 chr6:27835339-27835419 0.00018 52_[+4]_20 chr6:27059456-27059536 0.00018 39_[+4]_33 chr14:20937523-20937603 0.00018 12_[+4]_60 chr6:26555432-26555512 0.00018 5_[+4]_67 chr7:149344108-149344188 0.00018 35_[+4]_37 chr10:23286146-23286226 0.00018 14_[+4]_58 chr16:11350019-11350099 0.00023 64_[+4]_8 chr6:27763701-27763781 0.00023 12_[+4]_60 chr19:893358-893438 0.00023 48_[+4]_24 chr6:27636314-27636394 0.00023 22_[+4]_50 chr2:183859007-183859087 0.00023 58_[+4]_14 chrX:73072521-73072601 0.00026 51_[+4]_21 chr6:28921098-28921178 0.00029 65_[+4]_7 chr6:27129983-27130063 0.00029 29_[+4]_43 chr6:28574872-28574952 0.00029 18_[+4]_54 chr6:28626031-28626111 0.00033 72_[+4] chr17:8029000-8029080 0.00035 52_[+4]_20 chr20:62152079-62152159 0.00038 10_[+4]_62 chr2:30454356-30454436 0.00038 11_[+4]_61 chr11:2398498-2398578 0.0004 10_[+4]_62 chr6:28442384-28442464 0.00042 57_[+4]_15 chr2:20646789-20646869 0.00045 12_[+4]_60 chr19:4724698-4724778 0.00045 38_[+4]_34 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif HTWTAARM MEME-4 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF HTWTAARM width=8 seqs=43 chr6:134495963-134496043 ( 62) TTATAAAA 1 chr6:26311467-26311547 ( 54) TTATAAAA 1 chr6:27694408-27694488 ( 27) TTATAAAA 1 chr19:5434703-5434783 ( 70) TTATAAGA 1 chr2:108972727-108972807 ( 43) TTATAAGA 1 chr6:28505338-28505418 ( 62) TTATAAGA 1 chr6:28791147-28791227 ( 55) ATATAAAA 1 chr3:49449593-49449673 ( 20) CTATAAAA 1 chr19:4969054-4969134 ( 42) TTATAAGC 1 chr16:89989693-89989773 ( 26) CTATAAGA 1 chr6:27205389-27205469 ( 60) TTTTAAAA 1 chr1:68005120-68005200 ( 26) TTTTAAAA 1 chr6:28611161-28611241 ( 22) TTTTAAAA 1 chr17:8022401-8022481 ( 41) TTATAAGC 1 chr6:26319386-26319466 ( 36) TTTTAAGA 1 chr1:222638281-222638361 ( 9) ATATAAAC 1 chr6:28697025-28697105 ( 37) ATATAAGC 1 chr6:28849103-28849183 ( 37) ATATAAGC 1 chr1:32801808-32801888 ( 52) ATATAAGC 1 chr11:64937647-64937727 ( 29) ATATAAGC 1 chr6:27835339-27835419 ( 53) ATATAAGC 1 chr6:27059456-27059536 ( 40) ATATAAGC 1 chr14:20937523-20937603 ( 13) ATATAAGC 1 chr6:26555432-26555512 ( 6) ATTTAAAA 1 chr7:149344108-149344188 ( 36) CTATAAAC 1 chr10:23286146-23286226 ( 15) ATTTAAAA 1 chr16:11350019-11350099 ( 65) TTTTAAAC 1 chr6:27763701-27763781 ( 13) CTATAAGC 1 chr19:893358-893438 ( 49) ATTTAAGA 1 chr6:27636314-27636394 ( 23) CTTTAAAA 1 chr2:183859007-183859087 ( 59) CTTTAAAA 1 chrX:73072521-73072601 ( 52) CTTTAAGA 1 chr6:28921098-28921178 ( 66) ATTTAAAC 1 chr6:27129983-27130063 ( 30) TTATAAAT 1 chr6:28574872-28574952 ( 19) TTATAAAT 1 chr6:28626031-28626111 ( 73) CTTTAAAC 1 chr17:8029000-8029080 ( 53) CTTTAAGC 1 chr20:62152079-62152159 ( 11) ATATAAGT 1 chr2:30454356-30454436 ( 12) CTATAAAT 1 chr11:2398498-2398578 ( 11) CTATAAGT 1 chr6:28442384-28442464 ( 58) TTTTAAGT 1 chr2:20646789-20646869 ( 13) CTTTAAAT 1 chr19:4724698-4724778 ( 39) CTTTAAAT 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif HTWTAARM MEME-4 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 10.2475 E= 1.1e+002 41 26 -1207 63 -1207 -1207 -1207 205 130 -1207 -1207 71 -1207 -1207 -1207 205 203 -1207 -1207 -1207 203 -1207 -1207 -1207 106 -1207 90 -1207 85 56 -1207 -37 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif HTWTAARM MEME-4 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 43 E= 1.1e+002 0.325581 0.302326 0.000000 0.372093 0.000000 0.000000 0.000000 1.000000 0.604651 0.000000 0.000000 0.395349 0.000000 0.000000 0.000000 1.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.511628 0.000000 0.488372 0.000000 0.441860 0.372093 0.000000 0.186047 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif HTWTAARM MEME-4 regular expression -------------------------------------------------------------------------------- [TAC]T[AT]TAA[AG][AC] -------------------------------------------------------------------------------- Time 16.31 secs. ******************************************************************************** ******************************************************************************** MOTIF TATACCCC MEME-5 width = 8 sites = 7 llr = 75 E-value = 7.0e+004 ******************************************************************************** -------------------------------------------------------------------------------- Motif TATACCCC MEME-5 Description -------------------------------------------------------------------------------- Simplified A :a:a::1: pos.-specific C ::::aa9a probability G :::::::: matrix T a:a::::: bits 2.1 ****** * 1.8 ****** * 1.6 ****** * 1.4 ******** Relative 1.2 ******** Entropy 1.0 ******** (15.5 bits) 0.8 ******** 0.6 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel TATACCCC consensus sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TATACCCC MEME-5 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr17:37310805-37310885 2 1.41e-05 c tatacccc cGCCACGCCA chr6:28779909-28779989 3 1.41e-05 gc tatacccc cTCTGGAAGA chr17:37310049-37310129 1 1.41e-05 . tatacccc cTCTGCCGGC chr7:149344108-149344188 1 1.41e-05 . tatacccc cACCCACTTA chr17:37017998-37018078 2 1.41e-05 c tatacccc cTCTACCAAA chr7:149052823-149052903 6 1.41e-05 tgagc tatacccc cAGTTACATT chr1:145397919-145397999 3 2.77e-05 ac tataccac caacgcATCT -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TATACCCC MEME-5 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr17:37310805-37310885 1.4e-05 1_[+5]_71 chr6:28779909-28779989 1.4e-05 2_[+5]_70 chr17:37310049-37310129 1.4e-05 [+5]_72 chr7:149344108-149344188 1.4e-05 [+5]_72 chr17:37017998-37018078 1.4e-05 1_[+5]_71 chr7:149052823-149052903 1.4e-05 5_[+5]_67 chr1:145397919-145397999 2.8e-05 2_[+5]_70 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TATACCCC MEME-5 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF TATACCCC width=8 seqs=7 chr17:37310805-37310885 ( 2) TATACCCC 1 chr6:28779909-28779989 ( 3) TATACCCC 1 chr17:37310049-37310129 ( 1) TATACCCC 1 chr7:149344108-149344188 ( 1) TATACCCC 1 chr17:37017998-37018078 ( 2) TATACCCC 1 chr7:149052823-149052903 ( 6) TATACCCC 1 chr1:145397919-145397999 ( 3) TATACCAC 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TATACCCC MEME-5 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 11.1915 E= 7.0e+004 -945 -945 -945 205 203 -945 -945 -945 -945 -945 -945 205 203 -945 -945 -945 -945 199 -945 -945 -945 199 -945 -945 -78 177 -945 -945 -945 199 -945 -945 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TATACCCC MEME-5 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 7 E= 7.0e+004 0.000000 0.000000 0.000000 1.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 1.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.142857 0.857143 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TATACCCC MEME-5 regular expression -------------------------------------------------------------------------------- TATACCCC -------------------------------------------------------------------------------- Time 19.99 secs. ******************************************************************************** ******************************************************************************** SUMMARY OF MOTIFS ******************************************************************************** -------------------------------------------------------------------------------- Combined block diagrams: non-overlapping sites with p-value < 0.0001 -------------------------------------------------------------------------------- SEQUENCE NAME COMBINED P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr14:21098656-21098736 4.11e-01 80 chr17:8022401-8022481 1.15e-01 80 chr16:3232692-3232772 7.72e-01 80 chr14:21099363-21099443 8.22e-03 13_[+2(1.52e-05)]_59 chr17:8029000-8029080 1.20e-02 80 chr17:19411429-19411509 4.32e-01 80 chr16:3230611-3230691 2.81e-02 1_[+2(1.52e-05)]_71 chr6:27688963-27689043 3.19e-01 80 chr6:27302824-27302904 8.30e-04 2_[+2(1.52e-05)]_6_[+3(4.53e-05)]_\ 56 chr6:28574872-28574952 1.79e-03 67_[+1(1.52e-05)]_5 chr14:21121338-21121418 1.60e-01 80 chr6:27471448-27471528 4.19e-01 80 chr6:28616038-28616118 1.06e-01 80 chr14:21149788-21149868 2.12e-02 67_[+1(1.52e-05)]_5 chr7:149052823-149052903 5.39e-02 5_[+5(1.41e-05)]_67 chr6:28611161-28611241 1.74e-03 67_[+1(1.52e-05)]_5 chr6:26305774-26305854 4.71e-01 80 chr16:71460330-71460410 3.73e-01 80 chr17:8042829-8042909 7.31e-01 80 chr14:21077556-21077636 3.27e-01 80 chr6:27694408-27694488 1.16e-02 26_[+4(1.24e-05)]_46 chr14:21151360-21151440 4.96e-01 80 chr16:3221984-3222064 9.34e-02 66_[+3(3.09e-05)]_6 chr6:27177565-27177645 9.89e-01 80 chr6:28694876-28694956 1.66e-02 42_[+1(5.79e-05)]_30 chr1:147825654-147825734 5.76e-01 80 chr17:37017998-37018078 7.14e-02 1_[+5(1.41e-05)]_71 chr19:12750989-12751069 9.75e-01 80 chr7:149028153-149028233 4.16e-01 80 chr1:222638281-222638361 7.88e-05 72_[+1(1.52e-05)] chr14:21152109-21152189 1.19e-02 67_[+3(3.09e-05)]_5 chr6:27529896-27529976 1.63e-01 80 chr14:21101102-21101182 2.99e-02 64_[+3(3.09e-05)]_8 chr6:26575731-26575811 4.14e-01 80 chr16:3225627-3225707 1.10e-02 71_[+1(1.52e-05)]_1 chr16:3241428-3241508 7.20e-01 80 chr16:3239563-3239643 1.12e-01 72_[+3(3.09e-05)] chr16:3246100-3246180 6.67e-03 59_[+1(1.52e-05)]_13 chr7:149404696-149404776 5.25e-03 70_[+1(1.52e-05)]_2 chr17:8089593-8089673 4.97e-01 80 chr13:31248164-31248244 9.10e-01 80 chr14:21131442-21131522 6.32e-01 80 chr6:27543791-27543871 7.63e-03 61_[+1(1.52e-05)]_11 chr14:21125706-21125786 2.97e-01 80 chr6:27559651-27559731 4.83e-01 80 chr8:67026328-67026408 4.36e-01 80 chr21:18827160-18827240 1.07e-01 80 chr6:27551263-27551343 4.89e-01 80 chr6:26331726-26331806 9.41e-01 80 chr13:95201957-95202037 1.23e-02 4_[+2(1.52e-05)]_68 chrX:18693084-18693164 6.03e-01 80 chr17:8023008-8023088 9.44e-01 80 chr14:89445377-89445457 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-------------------------------------------------------------------------------- ******************************************************************************** ******************************************************************************** Stopped because requested number of motifs (5) found. ******************************************************************************** CPU: c22n06.farnam.hpc.yale.internal ********************************************************************************