******************************************************************************** MEME - Motif discovery tool ******************************************************************************** MEME version 5.3.3 (Release date: Sun Feb 7 15:39:52 2021 -0800) For further information on how to interpret these results please access https://meme-suite.org/meme. To get a copy of the MEME Suite software please access https://meme-suite.org. ******************************************************************************** ******************************************************************************** REFERENCE ******************************************************************************** If you use this program in your research, please cite: Timothy L. Bailey and Charles Elkan, "Fitting a mixture model by expectation maximization to discover motifs in biopolymers", Proceedings of the Second International Conference on Intelligent Systems for Molecular Biology, pp. 28-36, AAAI Press, Menlo Park, California, 1994. ******************************************************************************** ******************************************************************************** TRAINING SET ******************************************************************************** PRIMARY SEQUENCES= ../result/final_prediction/K562/fasta/RankLinear0.6_40/TBL1XR1.fasta CONTROL SEQUENCES= --none-- ALPHABET= ACGT Sequence name Weight Length Sequence name Weight Length ------------- ------ ------ ------------- ------ ------ chr22:21221909-21221989 1.0000 80 chr9:131059066-131059146 1.0000 80 chr7:77429649-77429729 1.0000 80 chr9:80442442-80442522 1.0000 80 chr6:658411-658491 1.0000 80 chr2:28114118-28114198 1.0000 80 chr14:24768980-24769060 1.0000 80 chr9:19161758-19161838 1.0000 80 chr17:45955119-45955199 1.0000 80 chr3:196242237-196242317 1.0000 80 chr19:50862202-50862282 1.0000 80 chr7:150015253-150015333 1.0000 80 chr10:113943497-11394357 1.0000 80 chr19:36103574-36103654 1.0000 80 chr16:56496482-56496562 1.0000 80 chr8:128813051-128813131 1.0000 80 chr22:21132190-21132270 1.0000 80 chr18:3603156-3603236 1.0000 80 chr9:123659597-123659677 1.0000 80 chr9:132641524-132641604 1.0000 80 chr8:125029922-125030002 1.0000 80 chr12:52430770-52430850 1.0000 80 chr1:195868185-195868265 1.0000 80 chrX:102024013-102024093 1.0000 80 chr2:9748163-9748243 1.0000 80 chr12:89934462-89934542 1.0000 80 chr8:125486864-125486944 1.0000 80 chr10:29096398-29096478 1.0000 80 chr6:35311402-35311482 1.0000 80 chr1:15111375-15111455 1.0000 80 chr10:52086752-52086832 1.0000 80 chr20:57483019-57483099 1.0000 80 chr6:143381735-143381815 1.0000 80 chr6:134516859-134516939 1.0000 80 chr4:8442441-8442521 1.0000 80 chr5:177844523-177844603 1.0000 80 chr9:101694463-101694543 1.0000 80 chr1:156698620-156698700 1.0000 80 chr6:14951049-14951129 1.0000 80 chr5:95297736-95297816 1.0000 80 chr8:72743672-72743752 1.0000 80 chr17:73068166-73068246 1.0000 80 chr12:4262872-4262952 1.0000 80 chr8:126175782-126175862 1.0000 80 chr17:42264255-42264335 1.0000 80 chr2:176800509-176800589 1.0000 80 chr6:119468631-119468711 1.0000 80 chr22:22146152-22146232 1.0000 80 chr16:70471108-70471188 1.0000 80 chr22:21983656-21983736 1.0000 80 chr19:39310041-39310121 1.0000 80 chr9:107537703-107537783 1.0000 80 chr18:21120931-21121011 1.0000 80 chr15:65529438-65529518 1.0000 80 chr1:41616776-41616856 1.0000 80 chr8:94564276-94564356 1.0000 80 chr5:163786024-163786104 1.0000 80 chr22:23226275-23226355 1.0000 80 chr7:129882119-129882199 1.0000 80 chr11:67195867-67195947 1.0000 80 chr11:2799940-2800020 1.0000 80 chr16:71879817-71879897 1.0000 80 chr6:15736082-15736162 1.0000 80 chr6:26206347-26206427 1.0000 80 chr9:101649219-101649299 1.0000 80 chr11:126216122-12621620 1.0000 80 chr3:12994896-12994976 1.0000 80 chr2:8144496-8144576 1.0000 80 chr6:20458743-20458823 1.0000 80 chr3:52444005-52444085 1.0000 80 chr22:21213180-21213260 1.0000 80 chr4:185373066-185373146 1.0000 80 chr9:116131419-116131499 1.0000 80 chr1:20525618-20525698 1.0000 80 chr1:30664105-30664185 1.0000 80 chr2:171092771-171092851 1.0000 80 chr11:12147192-12147272 1.0000 80 chr20:3993450-3993530 1.0000 80 chr7:23312893-23312973 1.0000 80 chr14:73292889-73292969 1.0000 80 chr17:25856387-25856467 1.0000 80 chr12:62642804-62642884 1.0000 80 chr6:16131305-16131385 1.0000 80 chr6:70468258-70468338 1.0000 80 chr4:120375842-120375922 1.0000 80 chr12:109249760-10924984 1.0000 80 chr20:23113747-23113827 1.0000 80 chr14:69087048-69087128 1.0000 80 chr7:140624808-140624888 1.0000 80 chr2:19548148-19548228 1.0000 80 chr19:9649286-9649366 1.0000 80 chr2:227637528-227637608 1.0000 80 chr18:11947291-11947371 1.0000 80 chr6:15248939-15249019 1.0000 80 chr4:57253621-57253701 1.0000 80 chr18:8944045-8944125 1.0000 80 chr1:116958471-116958551 1.0000 80 chr14:23388091-23388171 1.0000 80 chr11:4115966-4116046 1.0000 80 chr1:2111917-2111997 1.0000 80 chr6:7899985-7900065 1.0000 80 chr6:43027142-43027222 1.0000 80 chr16:20756294-20756374 1.0000 80 chr6:119646062-119646142 1.0000 80 chr6:50927136-50927216 1.0000 80 chr4:95471641-95471721 1.0000 80 chr1:228296974-228297054 1.0000 80 chr1:246741184-246741264 1.0000 80 chr19:36119876-36119956 1.0000 80 chr1:2343987-2344067 1.0000 80 chr10:75716434-75716514 1.0000 80 chr2:174756195-174756275 1.0000 80 chr19:944267-944347 1.0000 80 chr7:70034592-70034672 1.0000 80 chr1:47644868-47644948 1.0000 80 chr16:85084880-85084960 1.0000 80 chr1:15110664-15110744 1.0000 80 chr7:6096383-6096463 1.0000 80 chr8:17388584-17388664 1.0000 80 chr6:34664709-34664789 1.0000 80 chr3:45133860-45133940 1.0000 80 chr15:95713993-95714073 1.0000 80 chr1:9489005-9489085 1.0000 80 chr9:100265893-100265973 1.0000 80 chr16:48644164-48644244 1.0000 80 chr16:19130366-19130446 1.0000 80 chr6:7975444-7975524 1.0000 80 chr1:8449182-8449262 1.0000 80 chr21:47875799-47875879 1.0000 80 chr2:15394172-15394252 1.0000 80 chr2:39666905-39666985 1.0000 80 chr3:193721049-193721129 1.0000 80 chr5:111885613-111885693 1.0000 80 chr3:142569295-142569375 1.0000 80 chr15:73076071-73076151 1.0000 80 chr16:86588786-86588866 1.0000 80 chr17:46632788-46632868 1.0000 80 chr11:22774615-22774695 1.0000 80 chr17:62409465-62409545 1.0000 80 chr16:21623233-21623313 1.0000 80 chr1:157232367-157232447 1.0000 80 chr6:139456081-139456161 1.0000 80 chr9:33001612-33001692 1.0000 80 chr6:151409390-151409470 1.0000 80 chr12:10766144-10766224 1.0000 80 chr22:39097029-39097109 1.0000 80 chr8:102064059-102064139 1.0000 80 chr6:108899904-108899984 1.0000 80 chr6:106968854-106968934 1.0000 80 chr2:86221200-86221280 1.0000 80 chr3:150169164-150169244 1.0000 80 chr12:94151899-94151979 1.0000 80 chr7:66309926-66310006 1.0000 80 chr22:22302129-22302209 1.0000 80 chr2:68290151-68290231 1.0000 80 chr2:75089572-75089652 1.0000 80 chr9:140083021-140083101 1.0000 80 chr1:22013761-22013841 1.0000 80 chr17:43242858-43242938 1.0000 80 chr6:36830191-36830271 1.0000 80 chr6:157814385-157814465 1.0000 80 chr2:46666845-46666925 1.0000 80 chr15:92021968-92022048 1.0000 80 chr16:88772825-88772905 1.0000 80 chr3:193571576-193571656 1.0000 80 chr11:78003359-78003439 1.0000 80 chr12:132628907-13262898 1.0000 80 chr5:55381185-55381265 1.0000 80 chr3:177077781-177077861 1.0000 80 chr17:33914235-33914315 1.0000 80 chr5:10507774-10507854 1.0000 80 chr15:64754165-64754245 1.0000 80 chr15:70384411-70384491 1.0000 80 chr5:131758498-131758578 1.0000 80 chr5:89940136-89940216 1.0000 80 chr21:43430420-43430500 1.0000 80 chr16:85595016-85595096 1.0000 80 chr2:8666430-8666510 1.0000 80 chr7:150736612-150736692 1.0000 80 chr19:53664584-53664664 1.0000 80 chr2:119496733-119496813 1.0000 80 chr10:11183640-11183720 1.0000 80 chr8:28745657-28745737 1.0000 80 chr6:134339191-134339271 1.0000 80 chr19:45943196-45943276 1.0000 80 chr17:28054032-28054112 1.0000 80 chr15:75432705-75432785 1.0000 80 chr7:45808614-45808694 1.0000 80 chr11:60609474-60609554 1.0000 80 chr5:70751392-70751472 1.0000 80 chr5:150153867-150153947 1.0000 80 chr12:123380718-12338079 1.0000 80 chr19:50979518-50979598 1.0000 80 chr6:154754113-154754193 1.0000 80 chr5:131083065-131083145 1.0000 80 chr9:37197223-37197303 1.0000 80 chr18:20248120-20248200 1.0000 80 chr9:119184930-119185010 1.0000 80 chr17:72711401-72711481 1.0000 80 chr2:231524059-231524139 1.0000 80 chr1:35965470-35965550 1.0000 80 chr7:129775682-129775762 1.0000 80 chr6:119863419-119863499 1.0000 80 chr17:685543-685623 1.0000 80 chr8:144629527-144629607 1.0000 80 chr6:134279185-134279265 1.0000 80 chr1:32394470-32394550 1.0000 80 chr5:67599715-67599795 1.0000 80 chr22:41999994-42000074 1.0000 80 chr10:29128704-29128784 1.0000 80 chr3:170496592-170496672 1.0000 80 chr16:85587843-85587923 1.0000 80 chr12:93963629-93963709 1.0000 80 chr10:126381576-12638165 1.0000 80 chr5:78810388-78810468 1.0000 80 chr2:29093140-29093220 1.0000 80 chr2:54798182-54798262 1.0000 80 chr10:86284926-86285006 1.0000 80 chr6:15062972-15063052 1.0000 80 chr8:42426796-42426876 1.0000 80 chr1:246276973-246277053 1.0000 80 chr7:70033939-70034019 1.0000 80 chr18:55334202-55334282 1.0000 80 chr4:492944-493024 1.0000 80 chr16:2021983-2022063 1.0000 80 chr6:136555841-136555921 1.0000 80 chr1:15106930-15107010 1.0000 80 chr5:137673164-137673244 1.0000 80 chr4:96170956-96171036 1.0000 80 chr21:43967356-43967436 1.0000 80 chr19:35453479-35453559 1.0000 80 chr6:41888860-41888940 1.0000 80 chr19:50837506-50837586 1.0000 80 chr12:133022750-13302283 1.0000 80 chr17:57861861-57861941 1.0000 80 chr17:42323530-42323610 1.0000 80 chr1:182169698-182169778 1.0000 80 chr6:126439334-126439414 1.0000 80 chr1:40626922-40627002 1.0000 80 chr1:42347841-42347921 1.0000 80 chr1:246274015-246274095 1.0000 80 chr5:42586905-42586985 1.0000 80 chr10:62587918-62587998 1.0000 80 chr2:8756084-8756164 1.0000 80 chr12:58138355-58138435 1.0000 80 chr8:68022164-68022244 1.0000 80 chrX:129890389-129890469 1.0000 80 chr20:44564033-44564113 1.0000 80 chr2:7050020-7050100 1.0000 80 chr8:98790245-98790325 1.0000 80 ******************************************************************************** ******************************************************************************** COMMAND LINE SUMMARY ******************************************************************************** This information can also be useful in the event you wish to report a problem with the MEME software. command: meme -oc ../result/final_prediction/K562/inference_raw/MEME/RankLinear0.6_40_TBL1XR1/ -dna -nmotifs 5 -w 8 -maxsize 250000 -nostatus ../result/final_prediction/K562/fasta/RankLinear0.6_40/TBL1XR1.fasta model: mod= zoops nmotifs= 5 evt= inf objective function: em= E-value of product of p-values starts= E-value of product of p-values strands: + width: minw= 8 maxw= 8 nsites: minsites= 2 maxsites= 250 wnsites= 0.8 theta: spmap= uni spfuzz= 0.5 em: prior= dirichlet b= 0.01 maxiter= 50 distance= 1e-05 trim: wg= 11 ws= 1 endgaps= yes data: n= 20000 N= 250 sample: seed= 0 hsfrac= 0 searchsize= 20000 norand= no csites= 1000 Letter frequencies in dataset: A 0.242 C 0.256 G 0.255 T 0.248 Background letter frequencies (from file dataset with add-one prior applied): A 0.242 C 0.256 G 0.255 T 0.248 Background model order: 0 ******************************************************************************** ******************************************************************************** MOTIF TGACGTCA MEME-1 width = 8 sites = 57 llr = 522 E-value = 2.6e-046 ******************************************************************************** -------------------------------------------------------------------------------- Motif TGACGTCA MEME-1 Description -------------------------------------------------------------------------------- Simplified A ::a::::a pos.-specific C :::9:1a: probability G :9:19::: matrix T 9::::9:: bits 2.0 ** 1.8 * ** 1.6 *** ** 1.4 *** * ** Relative 1.2 ******** Entropy 1.0 ******** (13.2 bits) 0.8 ******** 0.6 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel TGACGTCA consensus sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGACGTCA MEME-1 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr12:133022750-13302283 49 1.53e-05 CTCCTGTAGA TGACGTCA CCACAGTAAG chr17:685543-685623 19 1.53e-05 CCACGGGCCG TGACGTCA CTAGCCGCCG chr19:50979518-50979598 40 1.53e-05 GCGGGCTTTA TGACGTCA CACAAGAGCG chr12:123380718-12338079 10 1.53e-05 CCTGGGTCG TGACGTCA TCACCGCGCG chr5:70751392-70751472 14 1.53e-05 GCTGTGCGTC TGACGTCA TTCTGCGGCG chr11:60609474-60609554 50 1.53e-05 CGGCGACTCC TGACGTCA TAGGAAGGCG chr7:45808614-45808694 41 1.53e-05 GCGCCTTCCG TGACGTCA CAAGGGCGCG chr21:43430420-43430500 43 1.53e-05 ATCTTGAATT TGACGTCA TCCCACACCA chr17:33914235-33914315 20 1.53e-05 CGCACCCCGA TGACGTCA CGCGGCGACG chr12:132628907-13262898 70 1.53e-05 CGCGCAGTGG TGACGTCA CGG chr7:66309926-66310006 49 1.53e-05 GCGCCTTCGC TGACGTCA CAGGCGCGGG chr22:39097029-39097109 44 1.53e-05 GACGTAAGTC TGACGTCA TCGGCACCGG chr12:10766144-10766224 46 1.53e-05 CGCCTTGCAG TGACGTCA TCGCGCGGAA chr9:33001612-33001692 21 1.53e-05 CGCTGCGGGA TGACGTCA GAGGCCGGCT chr6:139456081-139456161 33 1.53e-05 GCGCGGGGCG TGACGTCA CGCGGGCGGT chr16:86588786-86588866 55 1.53e-05 TGGCGCGTAG TGACGTCA CCCGCTCCGC chr16:48644164-48644244 44 1.53e-05 CGACGGAAGT TGACGTCA CCCTCAGTCG chr1:9489005-9489085 38 1.53e-05 CGCGGGTGTG TGACGTCA TCTGAGAGCG chr19:36119876-36119956 38 1.53e-05 CCCGAATGTA TGACGTCA TGCGCCAGCG chr14:23388091-23388171 37 1.53e-05 TTTCTGCCCG TGACGTCA GGGGGGAGGC chr4:57253621-57253701 57 1.53e-05 CGTCGCTACG TGACGTCA GTGCGAGCGA chr6:15248939-15249019 36 1.53e-05 GTTGTCATTG TGACGTCA CAAAGGGACG chr19:9649286-9649366 49 1.53e-05 GGCGCACCGC TGACGTCA TTTACGCTCT chr2:19548148-19548228 61 1.53e-05 GAGGCCTCTG TGACGTCA CGGTGTCTGC chr7:140624808-140624888 15 1.53e-05 GTCACGGTCG TGACGTCA CCCCGGTGCG chr5:95297736-95297816 48 1.53e-05 TAATCATGTC TGACGTCA CGTCTGGTCG chr4:8442441-8442521 33 1.53e-05 CCCGCCTCCA TGACGTCA ACGCGCCGCG chrX:102024013-102024093 41 1.53e-05 CATAGTAACC TGACGTCA TATTAGCGAC chr19:36103574-36103654 33 1.53e-05 CGGCAACCGA TGACGTCA CTGTTGGCGC chr19:50862202-50862282 30 1.53e-05 AACCGTCATA TGACGTCA CTATGGCGTC chr2:28114118-28114198 53 1.53e-05 TTCCGTTCCA TGACGTCA GCAGGGCACA chr12:58138355-58138435 55 4.65e-05 GGCGTCATCG TGAGGTCA CTGCAGAACA chr16:2021983-2022063 61 4.65e-05 TCGCGCGCGG TGACGCCA TCGCAGCGCG chr4:492944-493024 48 4.65e-05 CCGGCGGACG TGACGCCA CTGTCGCTGC chr2:119496733-119496813 8 4.65e-05 gaccctt tgaggtca gtatagttat chr20:23113747-23113827 50 4.65e-05 ATGGGTGGAG TGAGGTCA TGGGCCTAGC chr4:120375842-120375922 18 4.65e-05 CGCGCTCTTG TGACGCCA CGGAAGGCGC chr16:71879817-71879897 55 4.65e-05 GGGACGAGCT TGACGCCA TCTCCGGGCG chr6:14951049-14951129 11 4.65e-05 caagttaaaa tgaggtca gcagggacgg chr6:143381735-143381815 69 6.15e-05 ACGAAAGAGA TGACGACA CGCC chr8:125486864-125486944 31 6.15e-05 CCATGGGTGA TGACGACA TGGGGAGCGT chr5:137673164-137673244 31 1.05e-04 GAACCGCCTA TGATGTCA TAATCACAAT chr5:78810388-78810468 65 1.05e-04 GTGCGGGGGA TGATGTCA CGCGGCCG chr6:106968854-106968934 8 1.05e-04 CCTTCTG TGACATCA GTCAACACTA chr2:15394172-15394252 56 1.05e-04 ctcctgcaga taacgtca ctattgtaga chr11:4115966-4116046 38 1.05e-04 CAGCGTCGAG TAACGTCA TTCGAACCCC chr6:15736082-15736162 69 1.05e-04 taaaccacac tgacatca tttc chr16:88772825-88772905 49 1.21e-04 GGCGCCACTC CGACGTCA TCGGGGCGCG chr1:228296974-228297054 17 1.21e-04 CTGCAGCCCA CGACGTCA CTGGCAGGCG chr19:50837506-50837586 33 1.37e-04 TACATCACTG TGGCGTCA TTATGACGGA chr1:156698620-156698700 6 1.37e-04 TTTTG TGGCGTCA CTGCACTGTT chr14:73292889-73292969 9 1.52e-04 AGAAATTG TGAAGTCA AAACAAGGGA chr1:2343987-2344067 23 2.13e-04 CGAGAACTGA TGACGGCA CGACGTGGCT chr3:52444005-52444085 35 2.13e-04 CGCCGGCGGC AGACGTCA CCAAGGCGCG chr5:163786024-163786104 15 2.13e-04 taacttattt tgacttca cagactcaca chr17:42264255-42264335 11 2.13e-04 AGAATACCTT TTACGTCA GCCCGTCTTA chr6:34664709-34664789 33 2.28e-04 CGTCCCCGCG TGACCTCA CCGCTGCGGG -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGACGTCA MEME-1 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr12:133022750-13302283 1.5e-05 48_[+1]_24 chr17:685543-685623 1.5e-05 18_[+1]_54 chr19:50979518-50979598 1.5e-05 39_[+1]_33 chr12:123380718-12338079 1.5e-05 9_[+1]_63 chr5:70751392-70751472 1.5e-05 13_[+1]_59 chr11:60609474-60609554 1.5e-05 49_[+1]_23 chr7:45808614-45808694 1.5e-05 40_[+1]_32 chr21:43430420-43430500 1.5e-05 42_[+1]_30 chr17:33914235-33914315 1.5e-05 19_[+1]_53 chr12:132628907-13262898 1.5e-05 69_[+1]_3 chr7:66309926-66310006 1.5e-05 48_[+1]_24 chr22:39097029-39097109 1.5e-05 43_[+1]_29 chr12:10766144-10766224 1.5e-05 45_[+1]_27 chr9:33001612-33001692 1.5e-05 20_[+1]_52 chr6:139456081-139456161 1.5e-05 32_[+1]_40 chr16:86588786-86588866 1.5e-05 54_[+1]_18 chr16:48644164-48644244 1.5e-05 43_[+1]_29 chr1:9489005-9489085 1.5e-05 37_[+1]_35 chr19:36119876-36119956 1.5e-05 37_[+1]_35 chr14:23388091-23388171 1.5e-05 36_[+1]_36 chr4:57253621-57253701 1.5e-05 56_[+1]_16 chr6:15248939-15249019 1.5e-05 35_[+1]_37 chr19:9649286-9649366 1.5e-05 48_[+1]_24 chr2:19548148-19548228 1.5e-05 60_[+1]_12 chr7:140624808-140624888 1.5e-05 14_[+1]_58 chr5:95297736-95297816 1.5e-05 47_[+1]_25 chr4:8442441-8442521 1.5e-05 32_[+1]_40 chrX:102024013-102024093 1.5e-05 40_[+1]_32 chr19:36103574-36103654 1.5e-05 32_[+1]_40 chr19:50862202-50862282 1.5e-05 29_[+1]_43 chr2:28114118-28114198 1.5e-05 52_[+1]_20 chr12:58138355-58138435 4.6e-05 54_[+1]_18 chr16:2021983-2022063 4.6e-05 60_[+1]_12 chr4:492944-493024 4.6e-05 47_[+1]_25 chr2:119496733-119496813 4.6e-05 7_[+1]_65 chr20:23113747-23113827 4.6e-05 49_[+1]_23 chr4:120375842-120375922 4.6e-05 17_[+1]_55 chr16:71879817-71879897 4.6e-05 54_[+1]_18 chr6:14951049-14951129 4.6e-05 10_[+1]_62 chr6:143381735-143381815 6.1e-05 68_[+1]_4 chr8:125486864-125486944 6.1e-05 30_[+1]_42 chr5:137673164-137673244 0.00011 30_[+1]_42 chr5:78810388-78810468 0.00011 64_[+1]_8 chr6:106968854-106968934 0.00011 7_[+1]_65 chr2:15394172-15394252 0.00011 55_[+1]_17 chr11:4115966-4116046 0.00011 37_[+1]_35 chr6:15736082-15736162 0.00011 68_[+1]_4 chr16:88772825-88772905 0.00012 48_[+1]_24 chr1:228296974-228297054 0.00012 16_[+1]_56 chr19:50837506-50837586 0.00014 32_[+1]_40 chr1:156698620-156698700 0.00014 5_[+1]_67 chr14:73292889-73292969 0.00015 8_[+1]_64 chr1:2343987-2344067 0.00021 22_[+1]_50 chr3:52444005-52444085 0.00021 34_[+1]_38 chr5:163786024-163786104 0.00021 14_[+1]_58 chr17:42264255-42264335 0.00021 10_[+1]_62 chr6:34664709-34664789 0.00023 32_[+1]_40 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGACGTCA MEME-1 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF TGACGTCA width=8 seqs=57 chr12:133022750-13302283 ( 49) TGACGTCA 1 chr17:685543-685623 ( 19) TGACGTCA 1 chr19:50979518-50979598 ( 40) TGACGTCA 1 chr12:123380718-12338079 ( 10) TGACGTCA 1 chr5:70751392-70751472 ( 14) TGACGTCA 1 chr11:60609474-60609554 ( 50) TGACGTCA 1 chr7:45808614-45808694 ( 41) TGACGTCA 1 chr21:43430420-43430500 ( 43) TGACGTCA 1 chr17:33914235-33914315 ( 20) TGACGTCA 1 chr12:132628907-13262898 ( 70) TGACGTCA 1 chr7:66309926-66310006 ( 49) TGACGTCA 1 chr22:39097029-39097109 ( 44) TGACGTCA 1 chr12:10766144-10766224 ( 46) TGACGTCA 1 chr9:33001612-33001692 ( 21) TGACGTCA 1 chr6:139456081-139456161 ( 33) TGACGTCA 1 chr16:86588786-86588866 ( 55) TGACGTCA 1 chr16:48644164-48644244 ( 44) TGACGTCA 1 chr1:9489005-9489085 ( 38) TGACGTCA 1 chr19:36119876-36119956 ( 38) TGACGTCA 1 chr14:23388091-23388171 ( 37) TGACGTCA 1 chr4:57253621-57253701 ( 57) TGACGTCA 1 chr6:15248939-15249019 ( 36) TGACGTCA 1 chr19:9649286-9649366 ( 49) TGACGTCA 1 chr2:19548148-19548228 ( 61) TGACGTCA 1 chr7:140624808-140624888 ( 15) TGACGTCA 1 chr5:95297736-95297816 ( 48) TGACGTCA 1 chr4:8442441-8442521 ( 33) TGACGTCA 1 chrX:102024013-102024093 ( 41) TGACGTCA 1 chr19:36103574-36103654 ( 33) TGACGTCA 1 chr19:50862202-50862282 ( 30) TGACGTCA 1 chr2:28114118-28114198 ( 53) TGACGTCA 1 chr12:58138355-58138435 ( 55) TGAGGTCA 1 chr16:2021983-2022063 ( 61) TGACGCCA 1 chr4:492944-493024 ( 48) TGACGCCA 1 chr2:119496733-119496813 ( 8) TGAGGTCA 1 chr20:23113747-23113827 ( 50) TGAGGTCA 1 chr4:120375842-120375922 ( 18) TGACGCCA 1 chr16:71879817-71879897 ( 55) TGACGCCA 1 chr6:14951049-14951129 ( 11) TGAGGTCA 1 chr6:143381735-143381815 ( 69) TGACGACA 1 chr8:125486864-125486944 ( 31) TGACGACA 1 chr5:137673164-137673244 ( 31) TGATGTCA 1 chr5:78810388-78810468 ( 65) TGATGTCA 1 chr6:106968854-106968934 ( 8) TGACATCA 1 chr2:15394172-15394252 ( 56) TAACGTCA 1 chr11:4115966-4116046 ( 38) TAACGTCA 1 chr6:15736082-15736162 ( 69) TGACATCA 1 chr16:88772825-88772905 ( 49) CGACGTCA 1 chr1:228296974-228297054 ( 17) CGACGTCA 1 chr19:50837506-50837586 ( 33) TGGCGTCA 1 chr1:156698620-156698700 ( 6) TGGCGTCA 1 chr14:73292889-73292969 ( 9) TGAAGTCA 1 chr1:2343987-2344067 ( 23) TGACGGCA 1 chr3:52444005-52444085 ( 35) AGACGTCA 1 chr5:163786024-163786104 ( 15) TGACTTCA 1 chr17:42264255-42264335 ( 11) TTACGTCA 1 chr6:34664709-34664789 ( 33) TGACCTCA 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGACGTCA MEME-1 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 9.55676 E= 2.6e-046 -378 -287 -1248 193 -278 -1248 190 -382 200 -1248 -286 -1248 -378 178 -186 -282 -278 -386 187 -382 -278 -187 -386 182 -1248 197 -1248 -1248 205 -1248 -1248 -1248 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGACGTCA MEME-1 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 57 E= 2.6e-046 0.017544 0.035088 0.000000 0.947368 0.035088 0.000000 0.947368 0.017544 0.964912 0.000000 0.035088 0.000000 0.017544 0.877193 0.070175 0.035088 0.035088 0.017544 0.929825 0.017544 0.035088 0.070175 0.017544 0.877193 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGACGTCA MEME-1 regular expression -------------------------------------------------------------------------------- TGACGTCA -------------------------------------------------------------------------------- Time 4.85 secs. ******************************************************************************** ******************************************************************************** MOTIF WGATAARV MEME-2 width = 8 sites = 55 llr = 449 E-value = 1.6e-019 ******************************************************************************** -------------------------------------------------------------------------------- Motif WGATAARV MEME-2 Description -------------------------------------------------------------------------------- Simplified A 6:a:aa33 pos.-specific C 1:::::13 probability G :a::::55 matrix T 3::a::1: bits 2.0 ***** 1.8 ***** 1.6 ***** 1.4 ***** Relative 1.2 ***** Entropy 1.0 ***** (11.8 bits) 0.8 ****** 0.6 ****** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel AGATAAGG consensus T AA sequence C -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif WGATAARV MEME-2 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr4:96170956-96171036 13 1.41e-05 CCACTTGGCC AGATAAGG CAGCCCTTAT chr1:32394470-32394550 36 1.41e-05 CCACTCAGAA AGATAAGG GAAGCAATTA chr2:231524059-231524139 31 1.41e-05 TGATAAGTGA AGATAAGG GCTCAGAGGG chr19:45943196-45943276 39 1.41e-05 AGCGGCCCCC AGATAAGG CAGGACGACT chr10:11183640-11183720 49 1.41e-05 GTGCCTTGAT AGATAAGg ctgaaaattc chr2:119496733-119496813 60 1.41e-05 aggttcagag agataagg tttttgccag chr2:8666430-8666510 57 1.41e-05 tgtatattac agataagg aaactgacac chr2:75089572-75089652 20 1.41e-05 TGTGCTGGGG AGATAAGG CCCATGTAGA chr1:157232367-157232447 69 1.41e-05 TCTTTAATCC AGATAAGG AGGT chr1:8449182-8449262 58 1.41e-05 CTGTGCTTCT AGATAAGG CCGAAAATGA chr2:174756195-174756275 42 1.41e-05 TGTTAAATAT AGATAAGG CAGCCACATA chr9:132641524-132641604 72 1.41e-05 CTGCCAGCAG AGATAAGG G chr8:128813051-128813131 13 1.41e-05 tgggttagac agataagg aacagcagac chr9:131059066-131059146 26 1.41e-05 AGGTTTCACC AGATAAGG GATTGATGGC chr6:136555841-136555921 69 6.95e-05 agtctaagct agataaga atgg chr10:86284926-86285006 13 6.95e-05 ctgcaggcac agataaga gaccttgcac chr10:29128704-29128784 31 6.95e-05 CGTAGCCTCT TGATAAGG GCTGCATTTA chr18:20248120-20248200 40 6.95e-05 GGGTTCGTGC TGATAAGG AAAGCCAGGC chr5:150153867-150153947 58 6.95e-05 CAGCGAATAC TGATAAGG CTGGGgctgt chr3:150169164-150169244 57 6.95e-05 GGAATTTGCC AGATAAGA TAAATGGCAT chr6:20458743-20458823 22 6.95e-05 TGGACCTTGG AGATAAGC TTCTATTCTT chr10:29096398-29096478 62 6.95e-05 GGCAGGCTTG AGATAAGC CTGGGTCAAG chr18:3603156-3603236 31 6.95e-05 TCAGGTCACC AGATAAAG GCAAGTCTTG chr16:56496482-56496562 72 6.95e-05 CTGGTAAGGA AGATAAAG G chr22:21221909-21221989 58 6.95e-05 CTCACAGGCA AGATAAGC CACCCTCACA chr2:7050020-7050100 59 1.38e-04 TGTGATCCTC TGATAAGA ATAGGTTCTC chr8:42426796-42426876 2 1.38e-04 C AGATAAAC TTTACACCCC chr1:35965470-35965550 52 1.38e-04 CTCTATCTTC TGATAAGA GGTAAGCTCA chr17:72711401-72711481 64 1.38e-04 CCACAGCAGC TGATAAGC CATGGCTTT chr5:131083065-131083145 27 1.38e-04 TGCTAGTAAA TGATAAAG ACCTACCTAG chr15:64754165-64754245 49 1.38e-04 GCTGCAGCAG AGATAAAC CGGTCCCTCT chr3:193571576-193571656 62 1.38e-04 ACACAGGTTC TGATAAGA TATAAGCTCC chr17:43242858-43242938 72 1.38e-04 CCCACAACAG AGATAAAC A chr8:102064059-102064139 41 1.38e-04 GGGTACTGCA TGATAAAG CTGTCAGTCT chr22:22146152-22146232 50 1.38e-04 acacaaagaa tgataaag caaatggggc chr8:126175782-126175862 34 1.38e-04 gggcaattgt agataaaa cgagattgta chr17:45955119-45955199 20 1.38e-04 AAGGCCAGAC AGATAAAC ACAGATGGAG chr2:8756084-8756164 69 1.51e-04 GGAGAGGAGC AGATAATG TGTG chr8:98790245-98790325 37 1.92e-04 AGTGTAGGTG TGATAAAA GGAGAGTACT chr15:70384411-70384491 68 1.92e-04 ACAGGTCAGC TGATAAAC TTGTT chr6:7899985-7900065 59 1.92e-04 TGCTCCTCTC TGATAAAA AGGAAACAAA chr1:116958471-116958551 44 1.92e-04 AGTGAGCCCT TGATAAAC CTTTGTTGAT chr6:119863419-119863499 37 2.33e-04 TGCTGTTGTC TGATAATG GTTATCGCTG chr6:157814385-157814465 20 2.33e-04 ACTTGCCCTG AGATAATC TTATCAGCGG chr7:150736612-150736692 66 2.75e-04 CTGTCTAGAC AGATAACA CTGTGGG chr21:47875799-47875879 44 2.75e-04 tgtggaagag agataacc aatccccact chr8:17388584-17388664 10 2.75e-04 AGGGCTGGG AGATAACA GGGCTGGTTT chr2:171092771-171092851 54 2.75e-04 TGTTCCTGAA AGATAACA TACCCCAAGG chr4:492944-493024 68 2.90e-04 GTCGCTGCGA CGATAAGG CCTGG chr3:12994896-12994976 13 2.90e-04 TGCTGAGGCC CGATAAGG CCCGGCCCAG chr21:43967356-43967436 66 3.18e-04 TGGGTTTCGC TGATAATA ACCTTAT chr10:75716434-75716514 19 3.18e-04 CAGTGGCAGC TGATAATC TGTGACCTGA chr18:21120931-21121011 49 3.18e-04 AGAAGGCATG TGATAATC TGTTTCAGTG chr9:80442442-80442522 33 3.46e-04 AGCCAGTGTC TGATAACA TTCTGATCTT chr15:92021968-92022048 40 3.89e-04 CTGCCGCACA CGATAAAG ATGCAACTGT -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif WGATAARV MEME-2 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr4:96170956-96171036 1.4e-05 12_[+2]_60 chr1:32394470-32394550 1.4e-05 35_[+2]_37 chr2:231524059-231524139 1.4e-05 30_[+2]_42 chr19:45943196-45943276 1.4e-05 38_[+2]_34 chr10:11183640-11183720 1.4e-05 48_[+2]_24 chr2:119496733-119496813 1.4e-05 59_[+2]_13 chr2:8666430-8666510 1.4e-05 56_[+2]_16 chr2:75089572-75089652 1.4e-05 19_[+2]_53 chr1:157232367-157232447 1.4e-05 68_[+2]_4 chr1:8449182-8449262 1.4e-05 57_[+2]_15 chr2:174756195-174756275 1.4e-05 41_[+2]_31 chr9:132641524-132641604 1.4e-05 71_[+2]_1 chr8:128813051-128813131 1.4e-05 12_[+2]_60 chr9:131059066-131059146 1.4e-05 25_[+2]_47 chr6:136555841-136555921 6.9e-05 68_[+2]_4 chr10:86284926-86285006 6.9e-05 12_[+2]_60 chr10:29128704-29128784 6.9e-05 30_[+2]_42 chr18:20248120-20248200 6.9e-05 39_[+2]_33 chr5:150153867-150153947 6.9e-05 57_[+2]_15 chr3:150169164-150169244 6.9e-05 56_[+2]_16 chr6:20458743-20458823 6.9e-05 21_[+2]_51 chr10:29096398-29096478 6.9e-05 61_[+2]_11 chr18:3603156-3603236 6.9e-05 30_[+2]_42 chr16:56496482-56496562 6.9e-05 71_[+2]_1 chr22:21221909-21221989 6.9e-05 57_[+2]_15 chr2:7050020-7050100 0.00014 58_[+2]_14 chr8:42426796-42426876 0.00014 1_[+2]_71 chr1:35965470-35965550 0.00014 51_[+2]_21 chr17:72711401-72711481 0.00014 63_[+2]_9 chr5:131083065-131083145 0.00014 26_[+2]_46 chr15:64754165-64754245 0.00014 48_[+2]_24 chr3:193571576-193571656 0.00014 61_[+2]_11 chr17:43242858-43242938 0.00014 71_[+2]_1 chr8:102064059-102064139 0.00014 40_[+2]_32 chr22:22146152-22146232 0.00014 49_[+2]_23 chr8:126175782-126175862 0.00014 33_[+2]_39 chr17:45955119-45955199 0.00014 19_[+2]_53 chr2:8756084-8756164 0.00015 68_[+2]_4 chr8:98790245-98790325 0.00019 36_[+2]_36 chr15:70384411-70384491 0.00019 67_[+2]_5 chr6:7899985-7900065 0.00019 58_[+2]_14 chr1:116958471-116958551 0.00019 43_[+2]_29 chr6:119863419-119863499 0.00023 36_[+2]_36 chr6:157814385-157814465 0.00023 19_[+2]_53 chr7:150736612-150736692 0.00028 65_[+2]_7 chr21:47875799-47875879 0.00028 43_[+2]_29 chr8:17388584-17388664 0.00028 9_[+2]_63 chr2:171092771-171092851 0.00028 53_[+2]_19 chr4:492944-493024 0.00029 67_[+2]_5 chr3:12994896-12994976 0.00029 12_[+2]_60 chr21:43967356-43967436 0.00032 65_[+2]_7 chr10:75716434-75716514 0.00032 18_[+2]_54 chr18:21120931-21121011 0.00032 48_[+2]_24 chr9:80442442-80442522 0.00035 32_[+2]_40 chr15:92021968-92022048 0.00039 39_[+2]_33 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif WGATAARV MEME-2 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF WGATAARV width=8 seqs=55 chr4:96170956-96171036 ( 13) AGATAAGG 1 chr1:32394470-32394550 ( 36) AGATAAGG 1 chr2:231524059-231524139 ( 31) AGATAAGG 1 chr19:45943196-45943276 ( 39) AGATAAGG 1 chr10:11183640-11183720 ( 49) AGATAAGG 1 chr2:119496733-119496813 ( 60) AGATAAGG 1 chr2:8666430-8666510 ( 57) AGATAAGG 1 chr2:75089572-75089652 ( 20) AGATAAGG 1 chr1:157232367-157232447 ( 69) AGATAAGG 1 chr1:8449182-8449262 ( 58) AGATAAGG 1 chr2:174756195-174756275 ( 42) AGATAAGG 1 chr9:132641524-132641604 ( 72) AGATAAGG 1 chr8:128813051-128813131 ( 13) AGATAAGG 1 chr9:131059066-131059146 ( 26) AGATAAGG 1 chr6:136555841-136555921 ( 69) AGATAAGA 1 chr10:86284926-86285006 ( 13) AGATAAGA 1 chr10:29128704-29128784 ( 31) TGATAAGG 1 chr18:20248120-20248200 ( 40) TGATAAGG 1 chr5:150153867-150153947 ( 58) TGATAAGG 1 chr3:150169164-150169244 ( 57) AGATAAGA 1 chr6:20458743-20458823 ( 22) AGATAAGC 1 chr10:29096398-29096478 ( 62) AGATAAGC 1 chr18:3603156-3603236 ( 31) AGATAAAG 1 chr16:56496482-56496562 ( 72) AGATAAAG 1 chr22:21221909-21221989 ( 58) AGATAAGC 1 chr2:7050020-7050100 ( 59) TGATAAGA 1 chr8:42426796-42426876 ( 2) AGATAAAC 1 chr1:35965470-35965550 ( 52) TGATAAGA 1 chr17:72711401-72711481 ( 64) TGATAAGC 1 chr5:131083065-131083145 ( 27) TGATAAAG 1 chr15:64754165-64754245 ( 49) AGATAAAC 1 chr3:193571576-193571656 ( 62) TGATAAGA 1 chr17:43242858-43242938 ( 72) AGATAAAC 1 chr8:102064059-102064139 ( 41) TGATAAAG 1 chr22:22146152-22146232 ( 50) TGATAAAG 1 chr8:126175782-126175862 ( 34) AGATAAAA 1 chr17:45955119-45955199 ( 20) AGATAAAC 1 chr2:8756084-8756164 ( 69) AGATAATG 1 chr8:98790245-98790325 ( 37) TGATAAAA 1 chr15:70384411-70384491 ( 68) TGATAAAC 1 chr6:7899985-7900065 ( 59) TGATAAAA 1 chr1:116958471-116958551 ( 44) TGATAAAC 1 chr6:119863419-119863499 ( 37) TGATAATG 1 chr6:157814385-157814465 ( 20) AGATAATC 1 chr7:150736612-150736692 ( 66) AGATAACA 1 chr21:47875799-47875879 ( 44) AGATAACC 1 chr8:17388584-17388664 ( 10) AGATAACA 1 chr2:171092771-171092851 ( 54) AGATAACA 1 chr4:492944-493024 ( 68) CGATAAGG 1 chr3:12994896-12994976 ( 13) CGATAAGG 1 chr21:43967356-43967436 ( 66) TGATAATA 1 chr10:75716434-75716514 ( 19) TGATAATC 1 chr18:21120931-21121011 ( 49) TGATAATC 1 chr9:80442442-80442522 ( 33) TGATAACA 1 chr15:92021968-92022048 ( 40) CGATAAAG 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif WGATAARV MEME-2 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 10.0332 E= 1.6e-019 131 -223 -1243 48 -1243 -1243 197 -1243 205 -1243 -1243 -1243 -1243 -1243 -1243 201 205 -1243 -1243 -1243 205 -1243 -1243 -1243 17 -149 105 -118 8 -1 95 -1243 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif WGATAARV MEME-2 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 55 E= 1.6e-019 0.600000 0.054545 0.000000 0.345455 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.272727 0.090909 0.527273 0.109091 0.254545 0.254545 0.490909 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif WGATAARV MEME-2 regular expression -------------------------------------------------------------------------------- [AT]GATAA[GA][GAC] -------------------------------------------------------------------------------- Time 8.49 secs. ******************************************************************************** ******************************************************************************** MOTIF CTTATCTS MEME-3 width = 8 sites = 57 llr = 449 E-value = 1.5e-014 ******************************************************************************** -------------------------------------------------------------------------------- Motif CTTATCTS MEME-3 Description -------------------------------------------------------------------------------- Simplified A 1::9::31 pos.-specific C 5::::a:5 probability G 1::1:::3 matrix T 2aa:a:71 bits 2.0 ** ** 1.8 ** ** 1.6 ***** 1.4 ***** Relative 1.2 ***** Entropy 1.0 ****** (11.4 bits) 0.8 ****** 0.6 ****** 0.4 ******* 0.2 ******** 0.0 -------- Multilevel CTTATCTC consensus T AG sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTTATCTS MEME-3 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr17:57861861-57861941 35 1.54e-05 atagactttt cttatctc tccaggagtc chr9:37197223-37197303 67 1.54e-05 GGAAGCAGCT CTTATCTC TCCAGA chr6:119646062-119646142 73 1.54e-05 tgtgacaacc cttatctc chr14:73292889-73292969 36 1.54e-05 ATAAATTTTC CTTATCTC TCTAAGACAT chr9:101694463-101694543 17 1.54e-05 CCGTCTCTGG CTTATCTC AAGGACACAT chr6:35311402-35311482 36 1.54e-05 GGCCATTCTT CTTATCTC AGCTTTAATA chr12:89934462-89934542 34 1.54e-05 aagggtggga cttatctc tctcttccct chr3:196242237-196242317 43 1.54e-05 TTTCAAAGAA CTTATCTC GTGGACACAG chr19:53664584-53664664 19 3.07e-05 aagcaagttg cttatctg ggctctcaag chr16:85595016-85595096 16 3.07e-05 CTCCGAGCCC CTTATCTG GTTCCTGTCG chr2:227637528-227637608 27 3.07e-05 TTTTAAGTAT CTTATCTG TAAGACACTA chr19:39310041-39310121 62 3.07e-05 taattaggtc cttatctg cttgagggtc chr6:14951049-14951129 36 3.07e-05 cggccctaat cttatctg actggtgtcc chr7:6096383-6096463 30 4.56e-05 TGCAGAAACC CTTATCAC AATGTTACAG chr6:50927136-50927216 19 4.56e-05 GGCAGTCAGC CTTATCAC CATTTCACAG chr1:195868185-195868265 45 4.56e-05 aataaacatt cttatcac cagacacagg chr15:95713993-95714073 22 6.05e-05 GCCTCAGGCT TTTATCTC CCTGACCCCT chr11:126216122-12621620 62 6.05e-05 GCCTTGAGTT TTTATCTC GGCAGGAAGA chr17:42323530-42323610 49 7.54e-05 GAATTACTTC CTTATCAG GGTGGGGTTC chr8:28745657-28745737 4 7.54e-05 atc cttatcag ttcaagagtc chr22:22302129-22302209 54 7.54e-05 GAGGGCTGTC CTTATCAG GAATTGCTAA chr9:100265893-100265973 41 7.54e-05 TCCGCCCCAC CTTATCAG GGTCTCACAC chr8:94564276-94564356 40 7.54e-05 GAAAACTTCC CTTATCAG GCATTTCTGA chr6:134516859-134516939 63 7.54e-05 TTCCAGGAAG CTTATCAG TTTTGTGTCT chr10:29128704-29128784 45 9.03e-05 AAGGGCTGCA TTTATCTG TGAGAAGAGC chr5:67599715-67599795 10 9.03e-05 tctgctctt tttatctg tctttaacca chr7:129775682-129775762 23 9.03e-05 CTGTGGGTTC TTTATCTG CTCATTATCT chr11:2799940-2800020 38 9.03e-05 CTACATGGAC TTTATCTG AAAGTAGCTG chr9:19161758-19161838 6 9.03e-05 AGTCA TTTATCTG TCTTATCATA chr4:96170956-96171036 26 1.20e-04 TAAGGCAGCC CTTATCTT CACTCTGCAC chr5:131758498-131758578 9 1.20e-04 TGGCTTGC ATTATCTC CAGACACAGG chr10:75716434-75716514 49 1.20e-04 ATAGCTATCC ATTATCTC ACTGTGGTTT chr4:95471641-95471721 51 1.20e-04 ACTTTGGTGT ATTATCTC TAGTAGCATT chr9:101649219-101649299 1 1.20e-04 . CTTATCTT GATTAGGAGG chr22:21132190-21132270 18 1.20e-04 GTGCTAAAAG CTTATCTT GTTTACTTAA chr9:119184930-119185010 71 1.49e-04 TAGTGCACAC TTTATCAC GA chr2:8144496-8144576 14 1.49e-04 AGGCCAAATG TTTATCAC TATCTCCCAC chr15:75432705-75432785 51 1.78e-04 TTTGTCTTCT GTTATCTC CCTGCTGGGT chr19:944267-944347 1 1.78e-04 . GTTATCTC CCAGGCGTGT chr6:26206347-26206427 47 1.78e-04 CTCCAGTTTT CTTATCTA AAACAGGCTC chr8:42426796-42426876 39 1.93e-04 AGTCAGGGCT TTTATCAG CAAATCTTTC chr16:85587843-85587923 37 2.22e-04 GATTTGGGGA ATTATCAC ATGGGGCCTT chr6:658411-658491 3 2.22e-04 ga attatcac cagcctgata chr10:126381576-12638165 27 2.51e-04 ACATGAGTCC TTTATCTT CAGGAGACAG chr17:73068166-73068246 4 2.51e-04 AGC TTTATCTT ATGTTATTTT chr12:4262872-4262952 46 2.65e-04 CCTGCCTGGG ATTATCAG AACTTTGCTA chr6:134279185-134279265 25 2.94e-04 CAGGCATCTG GTTATCAC TGATGGCAGA chr6:154754113-154754193 18 2.94e-04 GGAGGAAGGC CTTATCAA AAGAGCACAG chr17:28054032-28054112 8 2.94e-04 TCATTTT GTTATCAC ACATGTCTAT chr3:12994896-12994976 50 3.09e-04 AGGCTGCAGC ATTATCTT TAACGACTGT chr1:20525618-20525698 42 3.23e-04 GATAGTCCTT TTTATCTA CAATAAACAG chr2:8666430-8666510 13 3.68e-04 ctatctggtc cttgtctc ctctccccca chr9:107537703-107537783 39 3.68e-04 tagtctccat cttgtctc tttgacctct chr8:68022164-68022244 4 3.96e-04 ccc gttatctt atacagctgt chr1:15110664-15110744 59 3.96e-04 acccaccctg attatcta ggacagactc chr3:170496592-170496672 57 4.26e-04 tggaagacct cttgtctg atagcttgga chr5:78810388-78810468 13 5.46e-04 CGTCAGCGCG CTTCTCTC CGCACACACG -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTTATCTS MEME-3 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr17:57861861-57861941 1.5e-05 34_[+3]_38 chr9:37197223-37197303 1.5e-05 66_[+3]_6 chr6:119646062-119646142 1.5e-05 72_[+3] chr14:73292889-73292969 1.5e-05 35_[+3]_37 chr9:101694463-101694543 1.5e-05 16_[+3]_56 chr6:35311402-35311482 1.5e-05 35_[+3]_37 chr12:89934462-89934542 1.5e-05 33_[+3]_39 chr3:196242237-196242317 1.5e-05 42_[+3]_30 chr19:53664584-53664664 3.1e-05 18_[+3]_54 chr16:85595016-85595096 3.1e-05 15_[+3]_57 chr2:227637528-227637608 3.1e-05 26_[+3]_46 chr19:39310041-39310121 3.1e-05 61_[+3]_11 chr6:14951049-14951129 3.1e-05 35_[+3]_37 chr7:6096383-6096463 4.6e-05 29_[+3]_43 chr6:50927136-50927216 4.6e-05 18_[+3]_54 chr1:195868185-195868265 4.6e-05 44_[+3]_28 chr15:95713993-95714073 6.1e-05 21_[+3]_51 chr11:126216122-12621620 6.1e-05 61_[+3]_11 chr17:42323530-42323610 7.5e-05 48_[+3]_24 chr8:28745657-28745737 7.5e-05 3_[+3]_69 chr22:22302129-22302209 7.5e-05 53_[+3]_19 chr9:100265893-100265973 7.5e-05 40_[+3]_32 chr8:94564276-94564356 7.5e-05 39_[+3]_33 chr6:134516859-134516939 7.5e-05 62_[+3]_10 chr10:29128704-29128784 9e-05 44_[+3]_28 chr5:67599715-67599795 9e-05 9_[+3]_63 chr7:129775682-129775762 9e-05 22_[+3]_50 chr11:2799940-2800020 9e-05 37_[+3]_35 chr9:19161758-19161838 9e-05 5_[+3]_67 chr4:96170956-96171036 0.00012 25_[+3]_47 chr5:131758498-131758578 0.00012 8_[+3]_64 chr10:75716434-75716514 0.00012 48_[+3]_24 chr4:95471641-95471721 0.00012 50_[+3]_22 chr9:101649219-101649299 0.00012 [+3]_72 chr22:21132190-21132270 0.00012 17_[+3]_55 chr9:119184930-119185010 0.00015 70_[+3]_2 chr2:8144496-8144576 0.00015 13_[+3]_59 chr15:75432705-75432785 0.00018 50_[+3]_22 chr19:944267-944347 0.00018 [+3]_72 chr6:26206347-26206427 0.00018 46_[+3]_26 chr8:42426796-42426876 0.00019 38_[+3]_34 chr16:85587843-85587923 0.00022 36_[+3]_36 chr6:658411-658491 0.00022 2_[+3]_70 chr10:126381576-12638165 0.00025 26_[+3]_46 chr17:73068166-73068246 0.00025 3_[+3]_69 chr12:4262872-4262952 0.00027 45_[+3]_27 chr6:134279185-134279265 0.00029 24_[+3]_48 chr6:154754113-154754193 0.00029 17_[+3]_55 chr17:28054032-28054112 0.00029 7_[+3]_65 chr3:12994896-12994976 0.00031 49_[+3]_23 chr1:20525618-20525698 0.00032 41_[+3]_31 chr2:8666430-8666510 0.00037 12_[+3]_60 chr9:107537703-107537783 0.00037 38_[+3]_34 chr8:68022164-68022244 0.0004 3_[+3]_69 chr1:15110664-15110744 0.0004 58_[+3]_14 chr3:170496592-170496672 0.00043 56_[+3]_16 chr5:78810388-78810468 0.00055 12_[+3]_60 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTTATCTS MEME-3 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF CTTATCTS width=8 seqs=57 chr17:57861861-57861941 ( 35) CTTATCTC 1 chr9:37197223-37197303 ( 67) CTTATCTC 1 chr6:119646062-119646142 ( 73) CTTATCTC 1 chr14:73292889-73292969 ( 36) CTTATCTC 1 chr9:101694463-101694543 ( 17) CTTATCTC 1 chr6:35311402-35311482 ( 36) CTTATCTC 1 chr12:89934462-89934542 ( 34) CTTATCTC 1 chr3:196242237-196242317 ( 43) CTTATCTC 1 chr19:53664584-53664664 ( 19) CTTATCTG 1 chr16:85595016-85595096 ( 16) CTTATCTG 1 chr2:227637528-227637608 ( 27) CTTATCTG 1 chr19:39310041-39310121 ( 62) CTTATCTG 1 chr6:14951049-14951129 ( 36) CTTATCTG 1 chr7:6096383-6096463 ( 30) CTTATCAC 1 chr6:50927136-50927216 ( 19) CTTATCAC 1 chr1:195868185-195868265 ( 45) CTTATCAC 1 chr15:95713993-95714073 ( 22) TTTATCTC 1 chr11:126216122-12621620 ( 62) TTTATCTC 1 chr17:42323530-42323610 ( 49) CTTATCAG 1 chr8:28745657-28745737 ( 4) CTTATCAG 1 chr22:22302129-22302209 ( 54) CTTATCAG 1 chr9:100265893-100265973 ( 41) CTTATCAG 1 chr8:94564276-94564356 ( 40) CTTATCAG 1 chr6:134516859-134516939 ( 63) CTTATCAG 1 chr10:29128704-29128784 ( 45) TTTATCTG 1 chr5:67599715-67599795 ( 10) TTTATCTG 1 chr7:129775682-129775762 ( 23) TTTATCTG 1 chr11:2799940-2800020 ( 38) TTTATCTG 1 chr9:19161758-19161838 ( 6) TTTATCTG 1 chr4:96170956-96171036 ( 26) CTTATCTT 1 chr5:131758498-131758578 ( 9) ATTATCTC 1 chr10:75716434-75716514 ( 49) ATTATCTC 1 chr4:95471641-95471721 ( 51) ATTATCTC 1 chr9:101649219-101649299 ( 1) CTTATCTT 1 chr22:21132190-21132270 ( 18) CTTATCTT 1 chr9:119184930-119185010 ( 71) TTTATCAC 1 chr2:8144496-8144576 ( 14) TTTATCAC 1 chr15:75432705-75432785 ( 51) GTTATCTC 1 chr19:944267-944347 ( 1) GTTATCTC 1 chr6:26206347-26206427 ( 47) CTTATCTA 1 chr8:42426796-42426876 ( 39) TTTATCAG 1 chr16:85587843-85587923 ( 37) ATTATCAC 1 chr6:658411-658491 ( 3) ATTATCAC 1 chr10:126381576-12638165 ( 27) TTTATCTT 1 chr17:73068166-73068246 ( 4) TTTATCTT 1 chr12:4262872-4262952 ( 46) ATTATCAG 1 chr6:134279185-134279265 ( 25) GTTATCAC 1 chr6:154754113-154754193 ( 18) CTTATCAA 1 chr17:28054032-28054112 ( 8) GTTATCAC 1 chr3:12994896-12994976 ( 50) ATTATCTT 1 chr1:20525618-20525698 ( 42) TTTATCTA 1 chr2:8666430-8666510 ( 13) CTTGTCTC 1 chr9:107537703-107537783 ( 39) CTTGTCTC 1 chr8:68022164-68022244 ( 4) GTTATCTT 1 chr1:15110664-15110744 ( 59) ATTATCTA 1 chr3:170496592-170496672 ( 57) CTTGTCTG 1 chr5:78810388-78810468 ( 13) CTTCTCTC 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTTATCTS MEME-3 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 8.94323 E= 1.5e-014 -78 109 -154 -12 -1248 -1248 -1248 201 -1248 -1248 -1248 201 194 -386 -227 -1248 -1248 -1248 -1248 201 -1248 197 -1248 -1248 39 -1248 -1248 146 -178 89 39 -101 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTTATCTS MEME-3 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 57 E= 1.5e-014 0.140351 0.543860 0.087719 0.228070 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.929825 0.017544 0.052632 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 0.315789 0.000000 0.000000 0.684211 0.070175 0.473684 0.333333 0.122807 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTTATCTS MEME-3 regular expression -------------------------------------------------------------------------------- [CT]TTATC[TA][CG] -------------------------------------------------------------------------------- Time 12.02 secs. ******************************************************************************** ******************************************************************************** MOTIF TCYWGGAA MEME-4 width = 8 sites = 28 llr = 248 E-value = 3.3e-003 ******************************************************************************** -------------------------------------------------------------------------------- Motif TCYWGGAA MEME-4 Description -------------------------------------------------------------------------------- Simplified A :::32:aa pos.-specific C :a5::::: probability G :::28a:: matrix T a:55:::: bits 2.0 ** *** 1.8 ** *** 1.6 ** *** 1.4 ** *** Relative 1.2 ** **** Entropy 1.0 *** **** (12.8 bits) 0.8 *** **** 0.6 *** **** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel TCCTGGAA consensus TAA sequence G -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCYWGGAA MEME-4 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chrX:129890389-129890469 30 3.02e-05 GTTGCTTCTT TCTTGGAA ATGCTGCTCA chr7:70033939-70034019 2 3.02e-05 T TCTTGGAA GAGTTGGTAC chr6:134279185-134279265 72 3.02e-05 CATCTCTGTT TCTTGGAA A chr8:144629527-144629607 39 3.02e-05 ggtggggagt tcctggaa cggattgtcc chr9:37197223-37197303 53 3.02e-05 AGAATTCATG TCCTGGAA GCAGCTCTTA chr6:151409390-151409470 56 3.02e-05 TAGCTGCACT TCTTGGAA GAGATGATTG chr16:21623233-21623313 11 3.02e-05 TAGAGCCAAT TCCTGGAA ATCTGGTTCT chr8:17388584-17388664 27 3.02e-05 AGGGCTGGTT TCCTGGAA ATGGTGTAAT chr20:23113747-23113827 9 3.02e-05 CTAACAAT TCCTGGAA CTGTGAAGTC chr3:196242237-196242317 64 3.02e-05 GACACAGGTG TCCTGGAA TGCACTATA chr10:62587918-62587998 61 5.97e-05 GTAGTTGAAT TCCAGGAA ATACCACTGA chr21:43967356-43967436 31 5.97e-05 CATTGGCAGT TCTAGGAA TAGAGAATAT chr8:28745657-28745737 27 5.97e-05 gagtcacgtt tccaggaa gctgtcccct chr3:150169164-150169244 43 5.97e-05 CTGAACCTCT TCTAGGAA TTTGCCAGAT chr1:30664105-30664185 51 5.97e-05 CAGAGCAGCT TCCAGGAA CTGACAGCAA chr12:4262872-4262952 27 5.97e-05 CCACACTGAT TCCAGGAA GCCTGCCTGG chr6:134516859-134516939 54 5.97e-05 TATGTCTATT TCCAGGAA GCTTATCAGT chr7:77429649-77429729 12 5.97e-05 AAACAGTGGT TCCAGGAA ATATTTTTGC chr8:42426796-42426876 55 9.08e-05 AGCAAATCTT TCTGGGAA AGGATTTGCT chr3:45133860-45133940 1 9.08e-05 . TCTGGGAA GAGTTCCGga chr1:41616776-41616856 50 9.08e-05 ACTTAATCCT TCTGGGAA ACTCTGGATG chr10:52086752-52086832 47 9.08e-05 GCTTAGAGAT TCTGGGAA GGGTGGGGCT chr2:39666905-39666985 32 1.19e-04 ttagaagcat tcttagaa gtcatctaat chr17:25856387-25856467 63 1.19e-04 taggataaat tcctagaa gtggagtctg chr18:21120931-21121011 35 1.19e-04 CTGTCTGGCT TCTTAGAA GGCATGTGAT chr5:111885613-111885693 28 1.47e-04 TGTAGTAATC TCCAAGAA AACATGAGGA chr1:32394470-32394550 73 1.77e-04 CGCACCTGCT TCTGAGAA chr6:36830191-36830271 72 1.77e-04 gagtcaagct tctgagaa a -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCYWGGAA MEME-4 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chrX:129890389-129890469 3e-05 29_[+4]_43 chr7:70033939-70034019 3e-05 1_[+4]_71 chr6:134279185-134279265 3e-05 71_[+4]_1 chr8:144629527-144629607 3e-05 38_[+4]_34 chr9:37197223-37197303 3e-05 52_[+4]_20 chr6:151409390-151409470 3e-05 55_[+4]_17 chr16:21623233-21623313 3e-05 10_[+4]_62 chr8:17388584-17388664 3e-05 26_[+4]_46 chr20:23113747-23113827 3e-05 8_[+4]_64 chr3:196242237-196242317 3e-05 63_[+4]_9 chr10:62587918-62587998 6e-05 60_[+4]_12 chr21:43967356-43967436 6e-05 30_[+4]_42 chr8:28745657-28745737 6e-05 26_[+4]_46 chr3:150169164-150169244 6e-05 42_[+4]_30 chr1:30664105-30664185 6e-05 50_[+4]_22 chr12:4262872-4262952 6e-05 26_[+4]_46 chr6:134516859-134516939 6e-05 53_[+4]_19 chr7:77429649-77429729 6e-05 11_[+4]_61 chr8:42426796-42426876 9.1e-05 54_[+4]_18 chr3:45133860-45133940 9.1e-05 [+4]_72 chr1:41616776-41616856 9.1e-05 49_[+4]_23 chr10:52086752-52086832 9.1e-05 46_[+4]_26 chr2:39666905-39666985 0.00012 31_[+4]_41 chr17:25856387-25856467 0.00012 62_[+4]_10 chr18:21120931-21121011 0.00012 34_[+4]_38 chr5:111885613-111885693 0.00015 27_[+4]_45 chr1:32394470-32394550 0.00018 72_[+4] chr6:36830191-36830271 0.00018 71_[+4]_1 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCYWGGAA MEME-4 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF TCYWGGAA width=8 seqs=28 chrX:129890389-129890469 ( 30) TCTTGGAA 1 chr7:70033939-70034019 ( 2) TCTTGGAA 1 chr6:134279185-134279265 ( 72) TCTTGGAA 1 chr8:144629527-144629607 ( 39) TCCTGGAA 1 chr9:37197223-37197303 ( 53) TCCTGGAA 1 chr6:151409390-151409470 ( 56) TCTTGGAA 1 chr16:21623233-21623313 ( 11) TCCTGGAA 1 chr8:17388584-17388664 ( 27) TCCTGGAA 1 chr20:23113747-23113827 ( 9) TCCTGGAA 1 chr3:196242237-196242317 ( 64) TCCTGGAA 1 chr10:62587918-62587998 ( 61) TCCAGGAA 1 chr21:43967356-43967436 ( 31) TCTAGGAA 1 chr8:28745657-28745737 ( 27) TCCAGGAA 1 chr3:150169164-150169244 ( 43) TCTAGGAA 1 chr1:30664105-30664185 ( 51) TCCAGGAA 1 chr12:4262872-4262952 ( 27) TCCAGGAA 1 chr6:134516859-134516939 ( 54) TCCAGGAA 1 chr7:77429649-77429729 ( 12) TCCAGGAA 1 chr8:42426796-42426876 ( 55) TCTGGGAA 1 chr3:45133860-45133940 ( 1) TCTGGGAA 1 chr1:41616776-41616856 ( 50) TCTGGGAA 1 chr10:52086752-52086832 ( 47) TCTGGGAA 1 chr2:39666905-39666985 ( 32) TCTTAGAA 1 chr17:25856387-25856467 ( 63) TCCTAGAA 1 chr18:21120931-21121011 ( 35) TCTTAGAA 1 chr5:111885613-111885693 ( 28) TCCAAGAA 1 chr1:32394470-32394550 ( 73) TCTGAGAA 1 chr6:36830191-36830271 ( 72) TCTGAGAA 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCYWGGAA MEME-4 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 10.5697 E= 3.3e-003 -1145 -1145 -1145 201 -1145 197 -1145 -1145 -1145 97 -1145 101 41 -1145 -25 91 -17 -1145 163 -1145 -1145 -1145 197 -1145 205 -1145 -1145 -1145 205 -1145 -1145 -1145 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCYWGGAA MEME-4 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 28 E= 3.3e-003 0.000000 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.500000 0.000000 0.500000 0.321429 0.000000 0.214286 0.464286 0.214286 0.000000 0.785714 0.000000 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCYWGGAA MEME-4 regular expression -------------------------------------------------------------------------------- TC[CT][TAG][GA]GAA -------------------------------------------------------------------------------- Time 15.45 secs. ******************************************************************************** ******************************************************************************** MOTIF CTCCCMCA MEME-5 width = 8 sites = 18 llr = 170 E-value = 2.2e+002 ******************************************************************************** -------------------------------------------------------------------------------- Motif CTCCCMCA MEME-5 Description -------------------------------------------------------------------------------- Simplified A :::::6:8 pos.-specific C a2aaa4a: probability G :::::::: matrix T :8:::::2 bits 2.0 * *** * 1.8 * *** * 1.6 * *** * 1.4 ***** ** Relative 1.2 ***** ** Entropy 1.0 ******** (13.6 bits) 0.8 ******** 0.6 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel CTCCCACA consensus C sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTCCCMCA MEME-5 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr1:246276973-246277053 9 1.60e-05 atttgttt ctcccaca gacagggagg chr17:43242858-43242938 36 1.60e-05 CATTTCCCAT CTCCCACA CCCAGTACTC chr1:15110664-15110744 19 1.60e-05 ctcagctctg ctcccaca tcctttcaac chr12:109249760-10924984 69 1.60e-05 CCCCCACTCC CTCCCACA AAGA chr2:8144496-8144576 25 1.60e-05 TTATCACTAT CTCCCACA CCAGCCCTAC chr15:65529438-65529518 70 1.60e-05 CCATGAGACT CTCCCACA CAG chr7:77429649-77429729 46 1.60e-05 AATAGCCTGC CTCCCACA CAGACTGGCT chr22:41999994-42000074 65 3.29e-05 GGAACAGGGA CTCCCCCA GGGAGGAG chr2:8666430-8666510 23 3.29e-05 cttgtctcct ctccccca ggagaggctc chr17:62409465-62409545 16 3.29e-05 TCCACTGCCC CTCCCCCA TAGAGGGAAC chr1:116958471-116958551 13 3.29e-05 AGATACCTCC CTCCCCCA AGTGTGACCA chr12:4262872-4262952 12 3.29e-05 TGTTCCCCAG CTCCCCCA CACTGATTCC chr3:193571576-193571656 5 4.93e-05 TCAA CCCCCACA CCACAGGCCC chr12:62642804-62642884 6 4.93e-05 cgcat cccccaca cccatgcccc chr1:15106930-15107010 31 6.57e-05 GAGCCATgtc ctcccact cactgcctgg chr16:19130366-19130446 57 6.57e-05 CCTTTGGTAA CTCCCACT GACCAGTCTT chr22:21213180-21213260 46 8.31e-05 GGATGTGGGC CCCCCCCA GCCGACCTGC chr8:144629527-144629607 56 1.00e-04 acggattgtc ctccccct ttcagaccac -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTCCCMCA MEME-5 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr1:246276973-246277053 1.6e-05 8_[+5]_64 chr17:43242858-43242938 1.6e-05 35_[+5]_37 chr1:15110664-15110744 1.6e-05 18_[+5]_54 chr12:109249760-10924984 1.6e-05 68_[+5]_4 chr2:8144496-8144576 1.6e-05 24_[+5]_48 chr15:65529438-65529518 1.6e-05 69_[+5]_3 chr7:77429649-77429729 1.6e-05 45_[+5]_27 chr22:41999994-42000074 3.3e-05 64_[+5]_8 chr2:8666430-8666510 3.3e-05 22_[+5]_50 chr17:62409465-62409545 3.3e-05 15_[+5]_57 chr1:116958471-116958551 3.3e-05 12_[+5]_60 chr12:4262872-4262952 3.3e-05 11_[+5]_61 chr3:193571576-193571656 4.9e-05 4_[+5]_68 chr12:62642804-62642884 4.9e-05 5_[+5]_67 chr1:15106930-15107010 6.6e-05 30_[+5]_42 chr16:19130366-19130446 6.6e-05 56_[+5]_16 chr22:21213180-21213260 8.3e-05 45_[+5]_27 chr8:144629527-144629607 0.0001 55_[+5]_17 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTCCCMCA MEME-5 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF CTCCCMCA width=8 seqs=18 chr1:246276973-246277053 ( 9) CTCCCACA 1 chr17:43242858-43242938 ( 36) CTCCCACA 1 chr1:15110664-15110744 ( 19) CTCCCACA 1 chr12:109249760-10924984 ( 69) CTCCCACA 1 chr2:8144496-8144576 ( 25) CTCCCACA 1 chr15:65529438-65529518 ( 70) CTCCCACA 1 chr7:77429649-77429729 ( 46) CTCCCACA 1 chr22:41999994-42000074 ( 65) CTCCCCCA 1 chr2:8666430-8666510 ( 23) CTCCCCCA 1 chr17:62409465-62409545 ( 16) CTCCCCCA 1 chr1:116958471-116958551 ( 13) CTCCCCCA 1 chr12:4262872-4262952 ( 12) CTCCCCCA 1 chr3:193571576-193571656 ( 5) CCCCCACA 1 chr12:62642804-62642884 ( 6) CCCCCACA 1 chr1:15106930-15107010 ( 31) CTCCCACT 1 chr16:19130366-19130446 ( 57) CTCCCACT 1 chr22:21213180-21213260 ( 46) CCCCCCCA 1 chr8:144629527-144629607 ( 56) CTCCCCCT 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTCCCMCA MEME-5 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 10.8329 E= 2.2e+002 -1081 197 -1081 -1081 -1081 -62 -1081 175 -1081 197 -1081 -1081 -1081 197 -1081 -1081 -1081 197 -1081 -1081 134 60 -1081 -1081 -1081 197 -1081 -1081 179 -1081 -1081 -57 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTCCCMCA MEME-5 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 18 E= 2.2e+002 0.000000 1.000000 0.000000 0.000000 0.000000 0.166667 0.000000 0.833333 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.611111 0.388889 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.833333 0.000000 0.000000 0.166667 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTCCCMCA MEME-5 regular expression -------------------------------------------------------------------------------- CTCCC[AC]CA -------------------------------------------------------------------------------- Time 18.82 secs. ******************************************************************************** ******************************************************************************** SUMMARY OF MOTIFS ******************************************************************************** -------------------------------------------------------------------------------- Combined block diagrams: non-overlapping sites with p-value < 0.0001 -------------------------------------------------------------------------------- SEQUENCE NAME COMBINED P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr22:21221909-21221989 2.88e-02 57_[+2(6.95e-05)]_15 chr9:131059066-131059146 3.29e-02 25_[+2(1.41e-05)]_47 chr7:77429649-77429729 1.55e-03 11_[+4(5.97e-05)]_26_[+5(1.60e-05)]_\ 27 chr9:80442442-80442522 5.86e-02 80 chr6:658411-658491 1.20e-01 80 chr2:28114118-28114198 4.47e-02 52_[+1(1.53e-05)]_20 chr14:24768980-24769060 7.40e-01 80 chr9:19161758-19161838 1.93e-02 5_[+3(9.03e-05)]_67 chr17:45955119-45955199 1.84e-01 80 chr3:196242237-196242317 1.73e-03 42_[+3(1.54e-05)]_13_[+4(3.02e-05)]_\ 9 chr19:50862202-50862282 4.94e-02 29_[+1(1.53e-05)]_43 chr7:150015253-150015333 1.13e-01 80 chr10:113943497-11394357 8.19e-01 80 chr19:36103574-36103654 5.31e-02 32_[+1(1.53e-05)]_15_[+1(1.53e-05)]_\ 17 chr16:56496482-56496562 1.48e-02 71_[+2(6.95e-05)]_1 chr8:128813051-128813131 9.55e-02 12_[+2(1.41e-05)]_60 chr22:21132190-21132270 6.20e-02 80 chr18:3603156-3603236 5.01e-03 30_[+2(6.95e-05)]_42 chr9:123659597-123659677 6.84e-01 80 chr9:132641524-132641604 1.29e-01 71_[+2(1.41e-05)]_1 chr8:125029922-125030002 8.08e-01 80 chr12:52430770-52430850 6.68e-01 80 chr1:195868185-195868265 1.06e-02 44_[+3(4.56e-05)]_28 chrX:102024013-102024093 4.44e-02 40_[+1(1.53e-05)]_32 chr2:9748163-9748243 6.42e-01 80 chr12:89934462-89934542 1.16e-02 33_[+3(1.54e-05)]_39 chr8:125486864-125486944 1.04e-01 30_[+1(6.15e-05)]_42 chr10:29096398-29096478 1.01e-01 61_[+2(6.95e-05)]_11 chr6:35311402-35311482 8.24e-03 35_[+3(1.54e-05)]_37 chr1:15111375-15111455 2.59e-01 80 chr10:52086752-52086832 1.34e-01 46_[+4(9.08e-05)]_26 chr20:57483019-57483099 7.67e-01 80 chr6:143381735-143381815 6.70e-02 68_[+1(6.15e-05)]_4 chr6:134516859-134516939 7.95e-03 53_[+4(5.97e-05)]_1_[+3(7.54e-05)]_\ 10 chr4:8442441-8442521 1.97e-02 32_[+1(1.53e-05)]_40 chr5:177844523-177844603 1.46e-01 80 chr9:101694463-101694543 1.32e-02 16_[+3(1.54e-05)]_56 chr1:156698620-156698700 3.09e-02 80 chr6:14951049-14951129 5.33e-04 10_[+1(4.65e-05)]_17_[+3(3.07e-05)]_\ 37 chr5:95297736-95297816 1.25e-02 47_[+1(1.53e-05)]_25 chr8:72743672-72743752 5.52e-01 80 chr17:73068166-73068246 2.30e-01 80 chr12:4262872-4262952 1.19e-04 11_[+5(3.29e-05)]_7_[+4(5.97e-05)]_\ 46 chr8:126175782-126175862 7.47e-02 80 chr17:42264255-42264335 3.44e-01 80 chr2:176800509-176800589 8.05e-02 80 chr6:119468631-119468711 3.48e-01 80 chr22:22146152-22146232 1.22e-01 80 chr16:70471108-70471188 1.43e-01 80 chr22:21983656-21983736 3.98e-01 80 chr19:39310041-39310121 9.66e-03 61_[+3(3.07e-05)]_11 chr9:107537703-107537783 1.80e-01 80 chr18:21120931-21121011 1.05e-02 80 chr15:65529438-65529518 1.15e-02 69_[+5(1.60e-05)]_3 chr1:41616776-41616856 1.09e-02 49_[+4(9.08e-05)]_23 chr8:94564276-94564356 1.11e-02 39_[+3(7.54e-05)]_33 chr5:163786024-163786104 4.00e-02 80 chr22:23226275-23226355 3.60e-01 80 chr7:129882119-129882199 2.35e-01 80 chr11:67195867-67195947 5.17e-01 80 chr11:2799940-2800020 2.95e-01 37_[+3(9.03e-05)]_35 chr16:71879817-71879897 2.04e-02 54_[+1(4.65e-05)]_18 chr6:15736082-15736162 4.03e-02 80 chr6:26206347-26206427 6.45e-02 80 chr9:101649219-101649299 4.27e-02 80 chr11:126216122-12621620 8.81e-02 61_[+3(6.05e-05)]_11 chr3:12994896-12994976 3.38e-02 80 chr2:8144496-8144576 4.21e-03 24_[+5(1.60e-05)]_48 chr6:20458743-20458823 2.07e-02 21_[+2(6.95e-05)]_51 chr3:52444005-52444085 2.22e-01 80 chr22:21213180-21213260 4.17e-01 45_[+5(8.31e-05)]_27 chr4:185373066-185373146 4.09e-01 80 chr9:116131419-116131499 5.06e-02 80 chr1:20525618-20525698 1.27e-01 80 chr1:30664105-30664185 3.52e-02 50_[+4(5.97e-05)]_22 chr2:171092771-171092851 4.57e-02 80 chr11:12147192-12147272 2.77e-01 80 chr20:3993450-3993530 1.01e-01 80 chr7:23312893-23312973 3.46e-02 80 chr14:73292889-73292969 1.96e-03 35_[+3(1.54e-05)]_37 chr17:25856387-25856467 1.91e-01 80 chr12:62642804-62642884 7.26e-02 5_[+5(4.93e-05)]_67 chr6:16131305-16131385 3.99e-01 80 chr6:70468258-70468338 7.08e-01 80 chr4:120375842-120375922 9.64e-02 17_[+1(4.65e-05)]_55 chr12:109249760-10924984 1.07e-02 68_[+5(1.60e-05)]_4 chr20:23113747-23113827 6.02e-03 8_[+4(3.02e-05)]_33_[+1(4.65e-05)]_\ 23 chr14:69087048-69087128 4.96e-01 80 chr7:140624808-140624888 2.60e-02 14_[+1(1.53e-05)]_58 chr2:19548148-19548228 4.85e-02 60_[+1(1.53e-05)]_12 chr19:9649286-9649366 3.23e-02 48_[+1(1.53e-05)]_24 chr2:227637528-227637608 4.59e-02 26_[+3(3.07e-05)]_46 chr18:11947291-11947371 6.65e-01 80 chr6:15248939-15249019 1.00e-02 35_[+1(1.53e-05)]_37 chr4:57253621-57253701 7.47e-02 56_[+1(1.53e-05)]_16 chr18:8944045-8944125 5.18e-01 80 chr1:116958471-116958551 2.70e-03 12_[+5(3.29e-05)]_60 chr14:23388091-23388171 4.77e-02 17_[+1(4.65e-05)]_11_[+1(1.53e-05)]_\ 36 chr11:4115966-4116046 1.50e-01 80 chr1:2111917-2111997 9.26e-01 80 chr6:7899985-7900065 8.62e-02 80 chr6:43027142-43027222 3.10e-01 80 chr16:20756294-20756374 2.11e-01 80 chr6:119646062-119646142 1.51e-02 72_[+3(1.54e-05)] chr6:50927136-50927216 1.64e-01 18_[+3(4.56e-05)]_54 chr4:95471641-95471721 1.26e-01 80 chr1:228296974-228297054 3.84e-01 80 chr1:246741184-246741264 3.61e-01 80 chr19:36119876-36119956 7.36e-02 37_[+1(1.53e-05)]_35 chr1:2343987-2344067 1.61e-01 80 chr10:75716434-75716514 1.89e-02 80 chr2:174756195-174756275 2.34e-02 41_[+2(1.41e-05)]_31 chr19:944267-944347 9.70e-02 80 chr7:70034592-70034672 6.92e-01 80 chr1:47644868-47644948 4.72e-01 80 chr16:85084880-85084960 2.01e-01 80 chr1:15110664-15110744 1.03e-03 18_[+5(1.60e-05)]_54 chr7:6096383-6096463 3.24e-02 29_[+3(4.56e-05)]_43 chr8:17388584-17388664 4.07e-03 26_[+4(3.02e-05)]_46 chr6:34664709-34664789 3.54e-01 80 chr3:45133860-45133940 1.21e-01 [+4(9.08e-05)]_72 chr15:95713993-95714073 1.45e-02 21_[+3(6.05e-05)]_51 chr1:9489005-9489085 2.14e-02 37_[+1(1.53e-05)]_35 chr9:100265893-100265973 3.66e-02 40_[+3(7.54e-05)]_32 chr16:48644164-48644244 1.64e-02 43_[+1(1.53e-05)]_29 chr16:19130366-19130446 5.58e-02 56_[+5(6.57e-05)]_16 chr6:7975444-7975524 7.15e-01 80 chr1:8449182-8449262 6.66e-03 57_[+2(1.41e-05)]_15 chr21:47875799-47875879 1.10e-01 80 chr2:15394172-15394252 3.86e-03 80 chr2:39666905-39666985 8.94e-03 80 chr3:193721049-193721129 1.94e-01 80 chr5:111885613-111885693 4.85e-02 80 chr3:142569295-142569375 2.20e-01 80 chr15:73076071-73076151 7.14e-01 80 chr16:86588786-86588866 1.08e-01 54_[+1(1.53e-05)]_18 chr17:46632788-46632868 1.32e-01 80 chr11:22774615-22774695 1.35e-01 80 chr17:62409465-62409545 5.63e-02 15_[+5(3.29e-05)]_57 chr16:21623233-21623313 6.74e-02 10_[+4(3.02e-05)]_62 chr1:157232367-157232447 1.92e-03 68_[+2(1.41e-05)]_4 chr6:139456081-139456161 1.71e-01 32_[+1(1.53e-05)]_21_[+1(4.65e-05)]_\ 11 chr9:33001612-33001692 1.04e-01 20_[+1(1.53e-05)]_23_[+1(1.53e-05)]_\ 21 chr6:151409390-151409470 4.54e-03 55_[+4(3.02e-05)]_17 chr12:10766144-10766224 5.99e-02 45_[+1(1.53e-05)]_27 chr22:39097029-39097109 4.95e-02 43_[+1(1.53e-05)]_29 chr8:102064059-102064139 2.16e-01 80 chr6:108899904-108899984 6.43e-01 80 chr6:106968854-106968934 2.36e-02 80 chr2:86221200-86221280 3.24e-01 80 chr3:150169164-150169244 5.52e-04 42_[+4(5.97e-05)]_6_[+2(6.95e-05)]_\ 16 chr12:94151899-94151979 2.70e-01 80 chr7:66309926-66310006 7.73e-02 48_[+1(1.53e-05)]_24 chr22:22302129-22302209 2.27e-02 53_[+3(7.54e-05)]_19 chr2:68290151-68290231 1.11e-01 80 chr2:75089572-75089652 1.12e-01 19_[+2(1.41e-05)]_53 chr9:140083021-140083101 9.04e-01 80 chr1:22013761-22013841 9.10e-01 80 chr17:43242858-43242938 3.30e-03 35_[+5(1.60e-05)]_37 chr6:36830191-36830271 1.82e-01 80 chr6:157814385-157814465 2.10e-03 26_[+3(7.54e-05)]_46 chr2:46666845-46666925 7.46e-01 80 chr15:92021968-92022048 1.76e-01 80 chr16:88772825-88772905 9.14e-02 80 chr3:193571576-193571656 4.58e-03 4_[+5(4.93e-05)]_68 chr11:78003359-78003439 2.28e-01 80 chr12:132628907-13262898 5.99e-02 69_[+1(1.53e-05)]_3 chr5:55381185-55381265 3.97e-01 80 chr3:177077781-177077861 3.46e-01 80 chr17:33914235-33914315 1.20e-02 19_[+1(1.53e-05)]_15_[+1(1.53e-05)]_\ 30 chr5:10507774-10507854 3.35e-01 80 chr15:64754165-64754245 9.70e-03 80 chr15:70384411-70384491 2.30e-01 80 chr5:131758498-131758578 1.37e-01 80 chr5:89940136-89940216 5.04e-02 80 chr21:43430420-43430500 8.46e-03 42_[+1(1.53e-05)]_14_[+1(4.65e-05)]_\ 8 chr16:85595016-85595096 1.74e-02 15_[+3(3.07e-05)]_57 chr2:8666430-8666510 1.62e-04 22_[+5(3.29e-05)]_26_[+2(1.41e-05)]_\ 16 chr7:150736612-150736692 1.87e-02 80 chr19:53664584-53664664 4.82e-02 18_[+3(3.07e-05)]_54 chr2:119496733-119496813 4.07e-05 7_[+1(4.65e-05)]_44_[+2(1.41e-05)]_\ 13 chr10:11183640-11183720 2.50e-02 48_[+2(1.41e-05)]_24 chr8:28745657-28745737 1.27e-03 3_[+3(7.54e-05)]_15_[+4(5.97e-05)]_\ 46 chr6:134339191-134339271 5.75e-01 80 chr19:45943196-45943276 8.23e-03 38_[+2(1.41e-05)]_34 chr17:28054032-28054112 1.55e-01 80 chr15:75432705-75432785 2.80e-01 80 chr7:45808614-45808694 3.92e-02 40_[+1(1.53e-05)]_32 chr11:60609474-60609554 4.27e-02 49_[+1(1.53e-05)]_23 chr5:70751392-70751472 1.17e-01 13_[+1(1.53e-05)]_59 chr5:150153867-150153947 5.08e-02 57_[+2(6.95e-05)]_15 chr12:123380718-12338079 6.89e-02 9_[+1(1.53e-05)]_63 chr19:50979518-50979598 2.02e-02 12_[+1(1.53e-05)]_19_[+1(1.53e-05)]_\ 33 chr6:154754113-154754193 2.90e-01 80 chr5:131083065-131083145 4.97e-02 80 chr9:37197223-37197303 9.30e-04 52_[+4(3.02e-05)]_6_[+3(1.54e-05)]_\ 6 chr18:20248120-20248200 1.42e-01 39_[+2(6.95e-05)]_33 chr9:119184930-119185010 3.02e-01 80 chr17:72711401-72711481 1.03e-01 80 chr2:231524059-231524139 3.65e-02 30_[+2(1.41e-05)]_42 chr1:35965470-35965550 5.90e-03 80 chr7:129775682-129775762 2.27e-03 22_[+3(9.03e-05)]_50 chr6:119863419-119863499 3.51e-02 80 chr17:685543-685623 2.79e-02 18_[+1(1.53e-05)]_54 chr8:144629527-144629607 2.81e-03 17_[+4(5.97e-05)]_13_[+4(3.02e-05)]_\ 34 chr6:134279185-134279265 1.62e-03 71_[+4(3.02e-05)]_1 chr1:32394470-32394550 5.16e-03 35_[+2(1.41e-05)]_37 chr5:67599715-67599795 3.50e-02 9_[+3(9.03e-05)]_63 chr22:41999994-42000074 1.03e-01 64_[+5(3.29e-05)]_8 chr10:29128704-29128784 3.99e-03 30_[+2(6.95e-05)]_6_[+3(9.03e-05)]_\ 28 chr3:170496592-170496672 9.46e-02 80 chr16:85587843-85587923 9.99e-02 80 chr12:93963629-93963709 4.94e-01 80 chr10:126381576-12638165 1.86e-01 80 chr5:78810388-78810468 2.39e-02 80 chr2:29093140-29093220 8.04e-01 80 chr2:54798182-54798262 2.83e-01 80 chr10:86284926-86285006 1.05e-01 12_[+2(6.95e-05)]_45_[+2(6.95e-05)]_\ 7 chr6:15062972-15063052 5.16e-01 80 chr8:42426796-42426876 3.11e-04 54_[+4(9.08e-05)]_18 chr1:246276973-246277053 2.18e-02 8_[+5(1.60e-05)]_64 chr7:70033939-70034019 2.42e-02 1_[+4(3.02e-05)]_71 chr18:55334202-55334282 2.71e-01 80 chr4:492944-493024 2.92e-02 47_[+1(4.65e-05)]_25 chr16:2021983-2022063 2.77e-01 60_[+1(4.65e-05)]_12 chr6:136555841-136555921 1.47e-01 68_[+2(6.95e-05)]_4 chr1:15106930-15107010 1.53e-01 30_[+5(6.57e-05)]_42 chr5:137673164-137673244 9.34e-02 80 chr4:96170956-96171036 1.96e-03 12_[+2(1.41e-05)]_60 chr21:43967356-43967436 9.54e-03 30_[+4(5.97e-05)]_42 chr19:35453479-35453559 8.17e-01 80 chr6:41888860-41888940 1.66e-01 80 chr19:50837506-50837586 1.33e-01 80 chr12:133022750-13302283 1.22e-02 48_[+1(1.53e-05)]_24 chr17:57861861-57861941 3.29e-02 34_[+3(1.54e-05)]_38 chr17:42323530-42323610 2.63e-01 48_[+3(7.54e-05)]_24 chr1:182169698-182169778 9.12e-01 80 chr6:126439334-126439414 1.25e-01 80 chr1:40626922-40627002 7.27e-01 80 chr1:42347841-42347921 4.87e-01 80 chr1:246274015-246274095 4.16e-01 80 chr5:42586905-42586985 9.19e-01 80 chr10:62587918-62587998 2.28e-02 60_[+4(5.97e-05)]_12 chr2:8756084-8756164 8.34e-02 80 chr12:58138355-58138435 2.18e-01 54_[+1(4.65e-05)]_18 chr8:68022164-68022244 5.09e-01 80 chrX:129890389-129890469 7.05e-02 29_[+4(3.02e-05)]_43 chr20:44564033-44564113 1.58e-01 80 chr2:7050020-7050100 1.33e-02 80 chr8:98790245-98790325 1.41e-01 80 -------------------------------------------------------------------------------- ******************************************************************************** ******************************************************************************** Stopped because requested number of motifs (5) found. ******************************************************************************** CPU: c17n09.farnam.hpc.yale.internal ********************************************************************************