******************************************************************************** MEME - Motif discovery tool ******************************************************************************** MEME version 5.3.3 (Release date: Sun Feb 7 15:39:52 2021 -0800) For further information on how to interpret these results please access https://meme-suite.org/meme. To get a copy of the MEME Suite software please access https://meme-suite.org. ******************************************************************************** ******************************************************************************** REFERENCE ******************************************************************************** If you use this program in your research, please cite: Timothy L. Bailey and Charles Elkan, "Fitting a mixture model by expectation maximization to discover motifs in biopolymers", Proceedings of the Second International Conference on Intelligent Systems for Molecular Biology, pp. 28-36, AAAI Press, Menlo Park, California, 1994. ******************************************************************************** ******************************************************************************** TRAINING SET ******************************************************************************** PRIMARY SEQUENCES= ../result/final_prediction/K562/fasta/RankLinear0.6_40/STAT1.fasta CONTROL SEQUENCES= --none-- ALPHABET= ACGT Sequence name Weight Length Sequence name Weight Length ------------- ------ ------ ------------- ------ ------ chr20:36751436-36751516 1.0000 80 chr14:94576944-94577024 1.0000 80 chr18:43554213-43554293 1.0000 80 chr16:50699395-50699475 1.0000 80 chr8:29957325-29957405 1.0000 80 chr11:57333727-57333807 1.0000 80 chr15:92015887-92015967 1.0000 80 chr3:122283123-122283203 1.0000 80 chr4:89300514-89300594 1.0000 80 chr10:25026137-25026217 1.0000 80 chr1:185303423-185303503 1.0000 80 chr5:131832712-131832792 1.0000 80 chr2:97151892-97151972 1.0000 80 chr10:91174282-91174362 1.0000 80 chr11:5646130-5646210 1.0000 80 chr12:104995195-10499527 1.0000 80 chr18:60173635-60173715 1.0000 80 chr3:122399598-122399678 1.0000 80 chr1:39251924-39252004 1.0000 80 chr15:81400313-81400393 1.0000 80 chr12:121477036-12147711 1.0000 80 chr16:19707814-19707894 1.0000 80 chr11:615632-615712 1.0000 80 chr10:91087612-91087692 1.0000 80 chr10:91152276-91152356 1.0000 80 chr17:40264716-40264796 1.0000 80 chr12:113344699-11334477 1.0000 80 chr21:42792447-42792527 1.0000 80 chr11:4414904-4414984 1.0000 80 chr4:38285521-38285601 1.0000 80 chr8:144105606-144105686 1.0000 80 chr1:205216560-205216640 1.0000 80 chr7:92776946-92777026 1.0000 80 chr3:130791858-130791938 1.0000 80 chr2:231084689-231084769 1.0000 80 chr7:92747397-92747477 1.0000 80 chr21:38791958-38792038 1.0000 80 chr2:201248606-201248686 1.0000 80 chr12:102330151-10233023 1.0000 80 chr2:120989942-120990022 1.0000 80 chr12:113376105-11337618 1.0000 80 chr6:47382628-47382708 1.0000 80 chr2:231280823-231280903 1.0000 80 chr15:74287061-74287141 1.0000 80 chr10:91092176-91092256 1.0000 80 chr2:231200768-231200848 1.0000 80 chr17:77061361-77061441 1.0000 80 chr9:33081350-33081430 1.0000 80 chr3:5191305-5191385 1.0000 80 chr18:2641788-2641868 1.0000 80 chr9:32526255-32526335 1.0000 80 chr6:16237011-16237091 1.0000 80 chr4:17578595-17578675 1.0000 80 chr2:146481653-146481733 1.0000 80 chr9:71584588-71584668 1.0000 80 chr1:25682520-25682600 1.0000 80 chr8:144107938-144108018 1.0000 80 chr1:169337688-169337768 1.0000 80 chr1:27998785-27998865 1.0000 80 chr4:169239939-169240019 1.0000 80 chr11:117043904-11704398 1.0000 80 chr7:87834657-87834737 1.0000 80 chr2:74433412-74433492 1.0000 80 chr1:150534650-150534730 1.0000 80 chr2:7017754-7017834 1.0000 80 chr3:48514483-48514563 1.0000 80 chr22:46589862-46589942 1.0000 80 chr5:84943801-84943881 1.0000 80 chr7:149552532-149552612 1.0000 80 chr14:24630360-24630440 1.0000 80 chr6:10838826-10838906 1.0000 80 chr2:152146439-152146519 1.0000 80 chr11:313965-314045 1.0000 80 chr14:97297399-97297479 1.0000 80 chr1:154580665-154580745 1.0000 80 chr6:42158721-42158801 1.0000 80 chr4:73419390-73419470 1.0000 80 chr16:11406643-11406723 1.0000 80 chr6:100706024-100706104 1.0000 80 chr4:169401688-169401768 1.0000 80 chr6:36315524-36315604 1.0000 80 chr6:168241706-168241786 1.0000 80 chr2:37384094-37384174 1.0000 80 chr20:35579209-35579289 1.0000 80 chr3:172230374-172230454 1.0000 80 chr22:50978142-50978222 1.0000 80 chr3:171897709-171897789 1.0000 80 chr15:81615195-81615275 1.0000 80 chr19:17516531-17516611 1.0000 80 chr15:101137152-10113723 1.0000 80 chr7:36444533-36444613 1.0000 80 chr5:131826556-131826636 1.0000 80 chrX:154014325-154014405 1.0000 80 chr5:81763178-81763258 1.0000 80 chr21:35029618-35029698 1.0000 80 chr13:111527204-11152728 1.0000 80 chr5:119848599-119848679 1.0000 80 chr3:177332885-177332965 1.0000 80 chr15:57029724-57029804 1.0000 80 chr7:134832719-134832799 1.0000 80 chr2:26716571-26716651 1.0000 80 chr10:25156323-25156403 1.0000 80 chr17:41158728-41158808 1.0000 80 chr7:4660204-4660284 1.0000 80 chr11:64764505-64764585 1.0000 80 chr2:7005885-7005965 1.0000 80 chr15:75417763-75417843 1.0000 80 chr6:138043957-138044037 1.0000 80 chr19:8799353-8799433 1.0000 80 chr2:202084933-202085013 1.0000 80 chr3:172312543-172312623 1.0000 80 chr15:52024148-52024228 1.0000 80 chr1:11851017-11851097 1.0000 80 chr3:146262417-146262497 1.0000 80 chr7:100145711-100145791 1.0000 80 chr1:8812665-8812745 1.0000 80 chr17:26595403-26595483 1.0000 80 chr12:6445453-6445533 1.0000 80 chr6:42013470-42013550 1.0000 80 chr6:32821581-32821661 1.0000 80 chr2:38701190-38701270 1.0000 80 chr10:52304834-52304914 1.0000 80 chr19:50880910-50880990 1.0000 80 chr2:163175196-163175276 1.0000 80 chr2:28753816-28753896 1.0000 80 chr6:99281972-99282052 1.0000 80 chr5:39077199-39077279 1.0000 80 chr1:159047074-159047154 1.0000 80 chr14:74229269-74229349 1.0000 80 chr13:50070001-50070081 1.0000 80 chr1:152007201-152007281 1.0000 80 chr11:5710949-5711029 1.0000 80 chr7:120640183-120640263 1.0000 80 chr19:47760201-47760281 1.0000 80 chr22:36044411-36044491 1.0000 80 chr1:54842892-54842972 1.0000 80 chrX:48794449-48794529 1.0000 80 chr1:110453391-110453471 1.0000 80 chr9:108641637-108641717 1.0000 80 chr5:131680638-131680718 1.0000 80 chr7:92634374-92634454 1.0000 80 chr2:9904341-9904421 1.0000 80 chr2:240202051-240202131 1.0000 80 chr10:80719153-80719233 1.0000 80 chr3:36949602-36949682 1.0000 80 chr1:155163169-155163249 1.0000 80 chr1:948708-948788 1.0000 80 chr19:48018762-48018842 1.0000 80 chr19:893299-893379 1.0000 80 chr12:32174020-32174100 1.0000 80 chr12:12953556-12953636 1.0000 80 chr10:114851848-11485192 1.0000 80 chr16:11391451-11391531 1.0000 80 chr13:43566399-43566479 1.0000 80 chr5:43040458-43040538 1.0000 80 chr2:152118323-152118403 1.0000 80 chr15:45020978-45021058 1.0000 80 chr14:97284354-97284434 1.0000 80 chr16:31033980-31034060 1.0000 80 chrX:41190885-41190965 1.0000 80 chr14:100841767-10084184 1.0000 80 chr6:30457084-30457164 1.0000 80 chrX:40869487-40869567 1.0000 80 chr8:20060062-20060142 1.0000 80 chr20:62205543-62205623 1.0000 80 chr5:10627856-10627936 1.0000 80 chr2:99176946-99177026 1.0000 80 chr8:26150630-26150710 1.0000 80 chr8:10488036-10488116 1.0000 80 chr19:51727739-51727819 1.0000 80 chr7:74064475-74064555 1.0000 80 chr1:173640228-173640308 1.0000 80 chr12:56754195-56754275 1.0000 80 chr11:78356415-78356495 1.0000 80 chr8:103818634-103818714 1.0000 80 chr1:113480991-113481071 1.0000 80 chr1:6464831-6464911 1.0000 80 chr5:142604444-142604524 1.0000 80 chr19:10196907-10196987 1.0000 80 chr1:44514057-44514137 1.0000 80 chr17:60711460-60711540 1.0000 80 chr7:105924488-105924568 1.0000 80 chr16:17922035-17922115 1.0000 80 chr6:43597860-43597940 1.0000 80 chr15:43398349-43398429 1.0000 80 chr8:8864277-8864357 1.0000 80 chr9:96725353-96725433 1.0000 80 chr9:100881488-100881568 1.0000 80 chr17:80408780-80408860 1.0000 80 chr1:21670071-21670151 1.0000 80 chr21:45275152-45275232 1.0000 80 chr10:3975328-3975408 1.0000 80 chr18:23570649-23570729 1.0000 80 chr16:3313886-3313966 1.0000 80 chr5:131831521-131831601 1.0000 80 chr12:50665870-50665950 1.0000 80 chr22:18632813-18632893 1.0000 80 chr1:9834940-9835020 1.0000 80 chr7:2445739-2445819 1.0000 80 chr15:67095534-67095614 1.0000 80 chr1:22118088-22118168 1.0000 80 chr7:116688668-116688748 1.0000 80 chr2:216696251-216696331 1.0000 80 chr12:117463514-11746359 1.0000 80 chr15:98619910-98619990 1.0000 80 chr7:138794062-138794142 1.0000 80 chr10:3871190-3871270 1.0000 80 chr7:138794522-138794602 1.0000 80 chr2:216484885-216484965 1.0000 80 chr3:52115064-52115144 1.0000 80 chr19:10381709-10381789 1.0000 80 chr4:185395890-185395970 1.0000 80 chr12:14437621-14437701 1.0000 80 chr2:178107363-178107443 1.0000 80 chr17:30454490-30454570 1.0000 80 chr8:144629509-144629589 1.0000 80 chr6:126244562-126244642 1.0000 80 chr6:53178699-53178779 1.0000 80 chrX:138295709-138295789 1.0000 80 chr6:119634242-119634322 1.0000 80 chr9:90289670-90289750 1.0000 80 chr12:49484208-49484288 1.0000 80 chr19:4540157-4540237 1.0000 80 chr2:201990476-201990556 1.0000 80 chr17:57863954-57864034 1.0000 80 chr19:1132298-1132378 1.0000 80 chr16:48642597-48642677 1.0000 80 chr9:101614069-101614149 1.0000 80 chr2:191878973-191879053 1.0000 80 chr4:170548186-170548266 1.0000 80 chr17:27505523-27505603 1.0000 80 chr20:388956-389036 1.0000 80 chr3:93692775-93692855 1.0000 80 chr2:169856326-169856406 1.0000 80 chr2:55921012-55921092 1.0000 80 chr5:142965767-142965847 1.0000 80 chr6:15097485-15097565 1.0000 80 chr4:78656214-78656294 1.0000 80 chr12:127568046-12756812 1.0000 80 chr20:52516222-52516302 1.0000 80 chr2:75538120-75538200 1.0000 80 chr1:180554731-180554811 1.0000 80 chr2:20776597-20776677 1.0000 80 chr5:149957855-149957935 1.0000 80 chr2:86811361-86811441 1.0000 80 chr1:158979613-158979693 1.0000 80 chr11:65188828-65188908 1.0000 80 chrX:154564131-154564211 1.0000 80 chr20:60982761-60982841 1.0000 80 chr8:90996283-90996363 1.0000 80 ******************************************************************************** ******************************************************************************** COMMAND LINE SUMMARY ******************************************************************************** This information can also be useful in the event you wish to report a problem with the MEME software. command: meme -oc ../result/final_prediction/K562/inference_raw/MEME/RankLinear0.6_40_STAT1/ -dna -nmotifs 5 -w 8 -maxsize 250000 -nostatus ../result/final_prediction/K562/fasta/RankLinear0.6_40/STAT1.fasta model: mod= zoops nmotifs= 5 evt= inf objective function: em= E-value of product of p-values starts= E-value of product of p-values strands: + width: minw= 8 maxw= 8 nsites: minsites= 2 maxsites= 250 wnsites= 0.8 theta: spmap= uni spfuzz= 0.5 em: prior= dirichlet b= 0.01 maxiter= 50 distance= 1e-05 trim: wg= 11 ws= 1 endgaps= yes data: n= 20000 N= 250 sample: seed= 0 hsfrac= 0 searchsize= 20000 norand= no csites= 1000 Letter frequencies in dataset: A 0.247 C 0.247 G 0.243 T 0.264 Background letter frequencies (from file dataset with add-one prior applied): A 0.247 C 0.247 G 0.243 T 0.264 Background model order: 0 ******************************************************************************** ******************************************************************************** MOTIF TCCNGGAA MEME-1 width = 8 sites = 142 llr = 1028 E-value = 2.4e-087 ******************************************************************************** -------------------------------------------------------------------------------- Motif TCCNGGAA MEME-1 Description -------------------------------------------------------------------------------- Simplified A ::123:aa pos.-specific C :973:::: probability G :::379:: matrix T 9:22:1:: bits 2.0 * 1.8 ** 1.6 ** ** 1.4 ** *** Relative 1.2 ** *** Entropy 1.0 ** **** (10.4 bits) 0.8 *** **** 0.6 *** **** 0.4 *** **** 0.2 *** **** 0.0 -------- Multilevel TCCCGGAA consensus TGA sequence A -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCCNGGAA MEME-1 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr20:60982761-60982841 3 1.43e-05 CT TCCCGGAA GGGCCCGCGT chr12:49484208-49484288 19 1.43e-05 CAGTTGCATT TCCCGGAA AGCAGCCGCC chr7:138794522-138794602 41 1.43e-05 CCCCACCCAT TCCCGGAA AGAGCAGACC chr12:117463514-11746359 54 1.43e-05 GCACTGAAAT TCCCGGAA GCATTGCCTT chr15:67095534-67095614 44 1.43e-05 GGAAGGCATT TCCCGGAA TCTGGGAGGA chr1:9834940-9835020 33 1.43e-05 tatgggaaat tcccggaa actgaggact chr18:23570649-23570729 44 1.43e-05 ATCCTTTGTT TCCCGGAA GAAGGTAAAA chr15:43398349-43398429 20 1.43e-05 CCGGCCCGCT TCCCGGAA GCAAGCGTCA chr17:60711460-60711540 43 1.43e-05 ggtgggcaat tcccggaa ctgagggagt chr1:155163169-155163249 33 1.43e-05 CCCCACCACT TCCCGGAA TAGCCCCACC chr1:159047074-159047154 42 1.43e-05 ggcgggcaat tcccggaa tcggggtgcc chr10:52304834-52304914 32 1.43e-05 GGCAGCTATT TCCCGGAA GCACACAGAG chr1:11851017-11851097 34 1.43e-05 ACAGGACATT TCCCGGAA TAGAACAAGG chr19:10381709-10381789 13 2.84e-05 GCGCGAGGTT TCCGGGAA AGCAGCACCG chr5:142604444-142604524 39 2.84e-05 ACAGCTCTTT TCCGGGAA CTCACCCAGG chr5:43040458-43040538 22 2.84e-05 ACCACCCGTT TCCGGGAA ATGAGCGTTG chr5:131680638-131680718 15 2.84e-05 acctggtctt tccgggaa ctagccccat chr14:74229269-74229349 38 2.84e-05 CTGCAGCGCT TCCGGGAA AGCCCTGGAG chr12:6445453-6445533 19 2.84e-05 TTAAGTCAGA TCCGGGAA AGGGAAATCT chr13:111527204-11152728 30 2.84e-05 GCTCCCCCTT TCCGGGAA ACTCTTCAAT chr9:71584588-71584668 42 2.84e-05 CCGAGGCCCT TCCGGGAA TTGCTTTATG chr21:42792447-42792527 67 2.84e-05 AACTGAATTG TCCGGGAA ATTCGC chr5:131832712-131832792 51 2.84e-05 TCGAGGAGTT TCCGGGAA CCGAACCACG chr1:180554731-180554811 30 4.28e-05 GACTGTGGCT TCCAGGAA GCTCTGCCTC chr3:93692775-93692855 35 4.28e-05 CAAGGACATT TCCAGGAA GCTTTTCGGA chr8:144629509-144629589 36 4.28e-05 tcatgagttt tccaggaa aggggtgggg chr12:50665870-50665950 25 4.28e-05 TCTGGACATT TCCAGGAA GGGCCTGGCT chr9:96725353-96725433 7 4.28e-05 AGTGTT TCCAGGAA ATCTTGCTCA chr8:20060062-20060142 28 4.28e-05 AGTCACTGTT TCCAGGAA AAGCTATGAC chr15:81615195-81615275 73 4.28e-05 ACAGATGGCC TCCAGGAA chr2:146481653-146481733 37 4.28e-05 acctctgtct tccaggaa attgggtcat chr3:130791858-130791938 33 4.28e-05 CCATGTGACT TCCAGGAA GCCCTCTAGG chr1:205216560-205216640 45 4.28e-05 GAGCTGTCCT TCCAGGAA TGGGCGTGGC chr1:39251924-39252004 27 4.28e-05 TGACATCATT TCCAGGAA AGGCTTGTGG chr3:122399598-122399678 49 4.28e-05 CTGGGAGTTT TCCAGGAA ACGAAAGCGA chr8:29957325-29957405 43 4.28e-05 tctgctgatt tccaggaa aggaaagagg chr6:15097485-15097565 18 5.81e-05 CTCAGCCTCT TCCTGGAA ACTGTGGCAT chr5:142965767-142965847 20 5.81e-05 GTTAAATATT TCCTGGAA ATTGCCTGAG chr19:4540157-4540237 46 5.81e-05 CAAAATTGCT TCCTGGAA ATTGTTTCCT chr3:52115064-52115144 31 5.81e-05 ACCAGCAATT TCCTGGAA GCCATGGCCC chr16:31033980-31034060 14 5.81e-05 actttcactt tcctggaa gtctaaggcc chr9:108641637-108641717 47 5.81e-05 tcctgctgtt tcctggaa tcacctctga chr22:36044411-36044491 26 5.81e-05 GCCCATGATT TCCTGGAA GAGCCCTAGA chr19:8799353-8799433 72 5.81e-05 aaggagaggt tcctggaa g chr7:4660204-4660284 36 5.81e-05 CCACACCCTT TCCTGGAA GCCAAGTCAC chr15:101137152-10113723 44 5.81e-05 cccacccatt tcctggaa accctctcct chr4:73419390-73419470 37 5.81e-05 TCATTCTGCT TCCTGGAA ATGAGTCTGA chr1:25682520-25682600 37 5.81e-05 tcacctgatt tcctggaa gagcctccta chr16:19707814-19707894 43 5.81e-05 CCCGAGAGCT TCCTGGAA ATGACAGTTC chr14:94576944-94577024 38 5.81e-05 AGTTTCGGTT TCCTGGAA AATGAAACCT chr9:101614069-101614149 36 7.26e-05 ggcgaggact tcccagaa ctgagggctc chr6:53178699-53178779 62 7.26e-05 AGTGGATGTT TCCCAGAA AAGGCTGAGG chr1:22118088-22118168 26 7.26e-05 gatgggcatt tcccagaa ctgagagttc chr12:32174020-32174100 63 7.26e-05 ggtgggtaat tcccagaa ctgagggttc chr2:28753816-28753896 18 7.26e-05 aaactgaagt tcccagaa gtcatgtgac chr7:100145711-100145791 46 7.26e-05 GTGTCTGAGT TCCCAGAA GTACCCCCCT chr19:17516531-17516611 37 7.26e-05 AGTTTCAGTT TCCCAGAA AGGAGGTGGG chr2:231200768-231200848 40 7.26e-05 ggcaggcagt tcccagaa ttggattgcc chr20:36751436-36751516 44 7.26e-05 tgagcctgtt tcccagaa atgtgtgcat chr11:65188828-65188908 32 8.70e-05 TCACCAGTTT TCCGAGAA GCACAGGGAG chr2:231084689-231084769 41 8.70e-05 GGGCCGGGCT TCCGAGAA AAGAAAAGTG chr18:43554213-43554293 64 8.70e-05 ACATATGATT TCCGAGAA GTCATTCAT chr4:185395890-185395970 47 1.17e-04 TTTCATCATT TCTCGGAA AAGTCAATTT chr10:3975328-3975408 15 1.17e-04 TCATGCCAGT TCCAAGAA TTAACACTGC chr21:45275152-45275232 4 1.17e-04 GTT TCCAAGAA GTGACACTAG chr15:45020978-45021058 40 1.17e-04 CCTTCCCCTT TCTCGGAA AGCAGCTGGC chr2:120989942-120990022 40 1.17e-04 ACGGCTAACT TCCAAGAA CTGGGGTGCT chr5:149957855-149957935 37 1.32e-04 TATCGCCTTT TCTGGGAA GTCCCCAGCA chr7:116688668-116688748 55 1.32e-04 tgtcgtaaat tctgggaa gtcatgcaca chr16:3313886-3313966 51 1.32e-04 aatgggTTGT TCTGGGAA TTCGGGGAAG chr2:240202051-240202131 38 1.32e-04 CAGAGCTGTT TCTGGGAA GCCAGCTCCA chr1:152007201-152007281 29 1.32e-04 TTACAGACTT TCTGGGAA ACCGGCCTGG chr6:42158721-42158801 34 1.32e-04 CAGGACCATT TCTGGGAA ACGTCCAGCT chr14:24630360-24630440 52 1.32e-04 CCACGTGATT TCTGGGAA AAGGCCCTCC chr2:74433412-74433492 58 1.32e-04 GACTCTGACT TCTGGGAA ATAGCTTTCA chrX:40869487-40869567 46 1.48e-04 gaactccatt tcctagaa gcccctccct chr1:113480991-113481071 17 1.63e-04 AGATTCAAAG TCTAGGAA ACCTCACTTT chr2:97151892-97151972 57 1.63e-04 ATCTCAGGCT TCTAGGAA AGCGAAACTT chr16:11406643-11406723 45 1.79e-04 ACTTTCAGTT TCTTGGAA AGGCTGTCCT chrX:138295709-138295789 59 1.95e-04 cctggtgact tctcagaa ttcctgtgag chr14:100841767-10084184 52 1.95e-04 TCACCCAGAT TCTCAGAA ACACTTGAGC chr13:43566399-43566479 27 1.95e-04 AGTTTCGGTT TCTCAGAA TCAGCAGCAG chr4:169239939-169240019 26 1.95e-04 TCCTTTCTCC TCTCAGAA GCACTTAGGT chr12:104995195-10499527 52 1.95e-04 ACCTGCCCAT TCTCAGAA GCCCAGCTTT chr6:126244562-126244642 42 2.26e-04 TGTTATCTCT TCCCGTAA GTCAGCTCAG chr1:6464831-6464911 21 2.26e-04 CCGCGTTGCT TCCCGTAA GCCGCAAGGC chr11:5710949-5711029 23 2.26e-04 TTCTTTCACT TCTGAGAA TTTAACTTTC chr6:138043957-138044037 41 2.26e-04 GAGACAGCAT TCTGAGAA GGATCTAGAG chr11:313965-314045 64 2.26e-04 AATACACACT TCTGAGAA ACTGAAACG chr9:33081350-33081430 48 2.41e-04 CGCCCTGCTT TCCGGTAA ATGGGCCCCC chr2:20776597-20776677 42 2.71e-04 GCAGTTGCTT TCTAAGAA TTGAAGGACA chr17:41158728-41158808 52 2.71e-04 GGCAGGGATT TCACGGAA ATGAAAGTGG chr15:57029724-57029804 36 2.71e-04 tccttcccct tctaagaa gtcatttgtt chr14:97297399-97297479 42 2.71e-04 CTTGTGTGCT TCTAAGAA GTAGCTCCTG chr17:57863954-57864034 56 3.01e-04 CCCCTTCATT TCCAGTAA ACTGTTTGAG chr8:8864277-8864357 61 3.01e-04 GCATTACATT TCCAGTAA ATGTGTGTTG chr6:36315524-36315604 48 3.01e-04 GAGCCGTATT TCAGGGAA GGGGCGGGCC chrX:48794449-48794529 66 3.17e-04 CTGCTGCCTT TCTTAGAA GCCAGGA chrX:154564131-154564211 73 3.48e-04 TTATTGGTGT TCCTGTAA chr7:105924488-105924568 69 3.48e-04 TTCACAGAAA TCCTGTAA TGAC chr2:202084933-202085013 30 3.48e-04 ctcatgcatt tcaaggaa atcacttctt chr5:119848599-119848679 45 3.48e-04 ggaggggatt tcctgtaa atggacaggc chr21:38791958-38792038 21 3.48e-04 ACTTTCATTT TCCTGTAA GTCATTATGA chr4:38285521-38285601 42 3.48e-04 aaactgaaac tcaaggaa gtcagatgac chr1:110453391-110453471 20 3.95e-04 CAGGGTGATT TCCCATAA ACCACATGCC chr3:177332885-177332965 34 3.95e-04 TGAGTCCATT TCCCTGAA ATGACTGAGC chr6:16237011-16237091 24 3.95e-04 TTCATTTCCT TCCCTGAA ACTTCATGAA chr20:388956-389036 39 4.69e-04 AACTGGGGCC TCCCGGGA GGAGAGAGGG chr15:75417763-75417843 51 4.69e-04 GGttcccttt tcacagaa gaggaaacca chr4:17578595-17578675 51 4.69e-04 AGTTTCTATT TCCCGGGA GTTGCCCAGC chr11:615632-615712 56 4.69e-04 CGGGTCAGGC TCCCGGGA AAGCGAAACC chr6:119634242-119634322 51 5.72e-04 GCAGAGCAAT TACGGGAA AGGAAAGAAA chr2:216696251-216696331 54 5.72e-04 aggaacactt tcagAGAA ACCGAAAGTC chr8:10488036-10488116 63 5.72e-04 GGAGCTGGGG TCAGAGAA GGGAGCTTTG chr6:30457084-30457164 55 5.72e-04 TTCCCGTTCC TCTCGTAA CCTGGTCATG chr3:172230374-172230454 35 5.72e-04 GGCACTGACT TACGGGAA GGGGAAGTGA chr2:201248606-201248686 45 5.72e-04 TTAATGGGTT TCAGAGAA ACGAAAGTGA chr6:43597860-43597940 25 6.15e-04 CGGGGCAGTG GCCGGGAA TAGAAACTTG chr12:56754195-56754275 51 6.15e-04 CGCGCGTGAG CCCCGGAA CCGAAACTAG chr3:122283123-122283203 25 6.15e-04 AAGCGGCTCT GCCGGGAA CAGGGAGGGA chr4:78656214-78656294 66 7.05e-04 aagttaaaag tccaggga tgtgggc chr19:51727739-51727819 2 7.05e-04 t tccttgaa atgcatgagg chr2:38701190-38701270 35 7.05e-04 CAATATCCCT TCCTTGAA GGCTAAGCAT chr2:7017754-7017834 60 7.05e-04 TGAGTGTTAG TCAAAGAA GGTGTGTCCT chrX:154014325-154014405 30 7.35e-04 CACCCATTAT GCCAGGAA ATCTAGGAGG chr2:178107363-178107443 16 8.09e-04 CCAGCCAATT TACTGGAA CTCTCACCCA chr11:78356415-78356495 65 8.09e-04 GAGCCTTGGA CCCAGGAA GAGCTAGT chr14:97284354-97284434 39 8.09e-04 CCTGTTGAGA CCCAGGAA TGGATCCTTC chr19:47760201-47760281 7 8.09e-04 TTGCCT TACTGGAA GTGGGTCCAG chr6:100706024-100706104 64 8.56e-04 AAGGTTTGGT TCTTGTAA ATGAGTCTC chr19:1132298-1132378 26 9.15e-04 GGGGCTGACT TTCAGGAA ATGATGCCGG chr20:35579209-35579289 44 9.15e-04 ttccttcccc ttcaggaa aagcctcaat chr16:17922035-17922115 21 9.90e-04 tctgacagtt tctcataa aatgaaaccc chr9:32526255-32526335 13 9.90e-04 GCAGGGATTT TCCGAGGA AATGAGGCCG chr2:231280823-231280903 8 9.90e-04 GTCCGTA GCCCAGAA GGAGGTTAAA chr7:92634374-92634454 44 1.07e-03 GCTGTAGGTG TCTGATAA TACAAGGATT chr6:42013470-42013550 68 1.07e-03 TTGGCAGGGG CCCCAGAA CTTTC chr7:36444533-36444613 9 1.07e-03 ttgtttat ttctggaa ttttccatgt chr22:50978142-50978222 9 1.07e-03 gagtcatt tctgataa atggttatgt chr18:2641788-2641868 30 1.07e-03 CGGTTTCTTT TCTGATAA TCAGTTTCAT chr15:81400313-81400393 37 1.07e-03 cgtttcctcg tctgtgaa actgagacaC chr1:44514057-44514137 54 1.25e-03 AAAAGGGCTT TATGGGAA GGAAGATAAG -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCCNGGAA MEME-1 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr20:60982761-60982841 1.4e-05 2_[+1]_70 chr12:49484208-49484288 1.4e-05 18_[+1]_54 chr7:138794522-138794602 1.4e-05 40_[+1]_32 chr12:117463514-11746359 1.4e-05 53_[+1]_19 chr15:67095534-67095614 1.4e-05 43_[+1]_29 chr1:9834940-9835020 1.4e-05 32_[+1]_40 chr18:23570649-23570729 1.4e-05 43_[+1]_29 chr15:43398349-43398429 1.4e-05 19_[+1]_53 chr17:60711460-60711540 1.4e-05 42_[+1]_30 chr1:155163169-155163249 1.4e-05 32_[+1]_40 chr1:159047074-159047154 1.4e-05 41_[+1]_31 chr10:52304834-52304914 1.4e-05 31_[+1]_41 chr1:11851017-11851097 1.4e-05 33_[+1]_39 chr19:10381709-10381789 2.8e-05 12_[+1]_60 chr5:142604444-142604524 2.8e-05 38_[+1]_34 chr5:43040458-43040538 2.8e-05 21_[+1]_51 chr5:131680638-131680718 2.8e-05 14_[+1]_58 chr14:74229269-74229349 2.8e-05 37_[+1]_35 chr12:6445453-6445533 2.8e-05 18_[+1]_54 chr13:111527204-11152728 2.8e-05 29_[+1]_43 chr9:71584588-71584668 2.8e-05 41_[+1]_31 chr21:42792447-42792527 2.8e-05 66_[+1]_6 chr5:131832712-131832792 2.8e-05 50_[+1]_22 chr1:180554731-180554811 4.3e-05 29_[+1]_43 chr3:93692775-93692855 4.3e-05 34_[+1]_38 chr8:144629509-144629589 4.3e-05 35_[+1]_37 chr12:50665870-50665950 4.3e-05 24_[+1]_48 chr9:96725353-96725433 4.3e-05 6_[+1]_66 chr8:20060062-20060142 4.3e-05 27_[+1]_45 chr15:81615195-81615275 4.3e-05 72_[+1] chr2:146481653-146481733 4.3e-05 36_[+1]_36 chr3:130791858-130791938 4.3e-05 32_[+1]_40 chr1:205216560-205216640 4.3e-05 44_[+1]_28 chr1:39251924-39252004 4.3e-05 26_[+1]_46 chr3:122399598-122399678 4.3e-05 48_[+1]_24 chr8:29957325-29957405 4.3e-05 42_[+1]_30 chr6:15097485-15097565 5.8e-05 17_[+1]_55 chr5:142965767-142965847 5.8e-05 19_[+1]_53 chr19:4540157-4540237 5.8e-05 45_[+1]_27 chr3:52115064-52115144 5.8e-05 30_[+1]_42 chr16:31033980-31034060 5.8e-05 13_[+1]_59 chr9:108641637-108641717 5.8e-05 46_[+1]_26 chr22:36044411-36044491 5.8e-05 25_[+1]_47 chr19:8799353-8799433 5.8e-05 71_[+1]_1 chr7:4660204-4660284 5.8e-05 35_[+1]_37 chr15:101137152-10113723 5.8e-05 43_[+1]_29 chr4:73419390-73419470 5.8e-05 36_[+1]_36 chr1:25682520-25682600 5.8e-05 36_[+1]_36 chr16:19707814-19707894 5.8e-05 42_[+1]_30 chr14:94576944-94577024 5.8e-05 37_[+1]_35 chr9:101614069-101614149 7.3e-05 35_[+1]_37 chr6:53178699-53178779 7.3e-05 61_[+1]_11 chr1:22118088-22118168 7.3e-05 25_[+1]_47 chr12:32174020-32174100 7.3e-05 62_[+1]_10 chr2:28753816-28753896 7.3e-05 17_[+1]_55 chr7:100145711-100145791 7.3e-05 45_[+1]_27 chr19:17516531-17516611 7.3e-05 36_[+1]_36 chr2:231200768-231200848 7.3e-05 39_[+1]_33 chr20:36751436-36751516 7.3e-05 43_[+1]_29 chr11:65188828-65188908 8.7e-05 31_[+1]_41 chr2:231084689-231084769 8.7e-05 40_[+1]_32 chr18:43554213-43554293 8.7e-05 63_[+1]_9 chr4:185395890-185395970 0.00012 46_[+1]_26 chr10:3975328-3975408 0.00012 14_[+1]_58 chr21:45275152-45275232 0.00012 3_[+1]_69 chr15:45020978-45021058 0.00012 39_[+1]_33 chr2:120989942-120990022 0.00012 39_[+1]_33 chr5:149957855-149957935 0.00013 36_[+1]_36 chr7:116688668-116688748 0.00013 54_[+1]_18 chr16:3313886-3313966 0.00013 50_[+1]_22 chr2:240202051-240202131 0.00013 37_[+1]_35 chr1:152007201-152007281 0.00013 28_[+1]_44 chr6:42158721-42158801 0.00013 33_[+1]_39 chr14:24630360-24630440 0.00013 51_[+1]_21 chr2:74433412-74433492 0.00013 57_[+1]_15 chrX:40869487-40869567 0.00015 45_[+1]_27 chr1:113480991-113481071 0.00016 16_[+1]_56 chr2:97151892-97151972 0.00016 56_[+1]_16 chr16:11406643-11406723 0.00018 44_[+1]_28 chrX:138295709-138295789 0.00019 58_[+1]_14 chr14:100841767-10084184 0.00019 51_[+1]_21 chr13:43566399-43566479 0.00019 26_[+1]_46 chr4:169239939-169240019 0.00019 25_[+1]_47 chr12:104995195-10499527 0.00019 51_[+1]_21 chr6:126244562-126244642 0.00023 41_[+1]_31 chr1:6464831-6464911 0.00023 20_[+1]_52 chr11:5710949-5711029 0.00023 22_[+1]_50 chr6:138043957-138044037 0.00023 40_[+1]_32 chr11:313965-314045 0.00023 63_[+1]_9 chr9:33081350-33081430 0.00024 47_[+1]_25 chr2:20776597-20776677 0.00027 41_[+1]_31 chr17:41158728-41158808 0.00027 51_[+1]_21 chr15:57029724-57029804 0.00027 35_[+1]_37 chr14:97297399-97297479 0.00027 41_[+1]_31 chr17:57863954-57864034 0.0003 55_[+1]_17 chr8:8864277-8864357 0.0003 60_[+1]_12 chr6:36315524-36315604 0.0003 47_[+1]_25 chrX:48794449-48794529 0.00032 65_[+1]_7 chrX:154564131-154564211 0.00035 72_[+1] chr7:105924488-105924568 0.00035 68_[+1]_4 chr2:202084933-202085013 0.00035 29_[+1]_43 chr5:119848599-119848679 0.00035 44_[+1]_28 chr21:38791958-38792038 0.00035 20_[+1]_52 chr4:38285521-38285601 0.00035 41_[+1]_31 chr1:110453391-110453471 0.00039 19_[+1]_53 chr3:177332885-177332965 0.00039 33_[+1]_39 chr6:16237011-16237091 0.00039 23_[+1]_49 chr20:388956-389036 0.00047 38_[+1]_34 chr15:75417763-75417843 0.00047 50_[+1]_22 chr4:17578595-17578675 0.00047 50_[+1]_22 chr11:615632-615712 0.00047 55_[+1]_17 chr6:119634242-119634322 0.00057 50_[+1]_22 chr2:216696251-216696331 0.00057 53_[+1]_19 chr8:10488036-10488116 0.00057 62_[+1]_10 chr6:30457084-30457164 0.00057 54_[+1]_18 chr3:172230374-172230454 0.00057 34_[+1]_38 chr2:201248606-201248686 0.00057 44_[+1]_28 chr6:43597860-43597940 0.00062 24_[+1]_48 chr12:56754195-56754275 0.00062 50_[+1]_22 chr3:122283123-122283203 0.00062 24_[+1]_48 chr4:78656214-78656294 0.0007 65_[+1]_7 chr19:51727739-51727819 0.0007 1_[+1]_71 chr2:38701190-38701270 0.0007 34_[+1]_38 chr2:7017754-7017834 0.0007 59_[+1]_13 chrX:154014325-154014405 0.00073 29_[+1]_43 chr2:178107363-178107443 0.00081 15_[+1]_57 chr11:78356415-78356495 0.00081 64_[+1]_8 chr14:97284354-97284434 0.00081 38_[+1]_34 chr19:47760201-47760281 0.00081 6_[+1]_66 chr6:100706024-100706104 0.00086 63_[+1]_9 chr19:1132298-1132378 0.00091 25_[+1]_47 chr20:35579209-35579289 0.00091 43_[+1]_29 chr16:17922035-17922115 0.00099 20_[+1]_52 chr9:32526255-32526335 0.00099 12_[+1]_60 chr2:231280823-231280903 0.00099 7_[+1]_65 chr7:92634374-92634454 0.0011 43_[+1]_29 chr6:42013470-42013550 0.0011 67_[+1]_5 chr7:36444533-36444613 0.0011 8_[+1]_64 chr22:50978142-50978222 0.0011 8_[+1]_64 chr18:2641788-2641868 0.0011 29_[+1]_43 chr15:81400313-81400393 0.0011 36_[+1]_36 chr1:44514057-44514137 0.0012 53_[+1]_19 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCCNGGAA MEME-1 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF TCCNGGAA width=8 seqs=142 chr20:60982761-60982841 ( 3) TCCCGGAA 1 chr12:49484208-49484288 ( 19) TCCCGGAA 1 chr7:138794522-138794602 ( 41) TCCCGGAA 1 chr12:117463514-11746359 ( 54) TCCCGGAA 1 chr15:67095534-67095614 ( 44) TCCCGGAA 1 chr1:9834940-9835020 ( 33) TCCCGGAA 1 chr18:23570649-23570729 ( 44) TCCCGGAA 1 chr15:43398349-43398429 ( 20) TCCCGGAA 1 chr17:60711460-60711540 ( 43) TCCCGGAA 1 chr1:155163169-155163249 ( 33) TCCCGGAA 1 chr1:159047074-159047154 ( 42) TCCCGGAA 1 chr10:52304834-52304914 ( 32) TCCCGGAA 1 chr1:11851017-11851097 ( 34) TCCCGGAA 1 chr19:10381709-10381789 ( 13) TCCGGGAA 1 chr5:142604444-142604524 ( 39) TCCGGGAA 1 chr5:43040458-43040538 ( 22) TCCGGGAA 1 chr5:131680638-131680718 ( 15) TCCGGGAA 1 chr14:74229269-74229349 ( 38) TCCGGGAA 1 chr12:6445453-6445533 ( 19) TCCGGGAA 1 chr13:111527204-11152728 ( 30) TCCGGGAA 1 chr9:71584588-71584668 ( 42) TCCGGGAA 1 chr21:42792447-42792527 ( 67) TCCGGGAA 1 chr5:131832712-131832792 ( 51) TCCGGGAA 1 chr1:180554731-180554811 ( 30) TCCAGGAA 1 chr3:93692775-93692855 ( 35) TCCAGGAA 1 chr8:144629509-144629589 ( 36) TCCAGGAA 1 chr12:50665870-50665950 ( 25) TCCAGGAA 1 chr9:96725353-96725433 ( 7) TCCAGGAA 1 chr8:20060062-20060142 ( 28) TCCAGGAA 1 chr15:81615195-81615275 ( 73) TCCAGGAA 1 chr2:146481653-146481733 ( 37) TCCAGGAA 1 chr3:130791858-130791938 ( 33) TCCAGGAA 1 chr1:205216560-205216640 ( 45) TCCAGGAA 1 chr1:39251924-39252004 ( 27) TCCAGGAA 1 chr3:122399598-122399678 ( 49) TCCAGGAA 1 chr8:29957325-29957405 ( 43) TCCAGGAA 1 chr6:15097485-15097565 ( 18) TCCTGGAA 1 chr5:142965767-142965847 ( 20) TCCTGGAA 1 chr19:4540157-4540237 ( 46) TCCTGGAA 1 chr3:52115064-52115144 ( 31) TCCTGGAA 1 chr16:31033980-31034060 ( 14) TCCTGGAA 1 chr9:108641637-108641717 ( 47) TCCTGGAA 1 chr22:36044411-36044491 ( 26) TCCTGGAA 1 chr19:8799353-8799433 ( 72) TCCTGGAA 1 chr7:4660204-4660284 ( 36) TCCTGGAA 1 chr15:101137152-10113723 ( 44) TCCTGGAA 1 chr4:73419390-73419470 ( 37) TCCTGGAA 1 chr1:25682520-25682600 ( 37) TCCTGGAA 1 chr16:19707814-19707894 ( 43) TCCTGGAA 1 chr14:94576944-94577024 ( 38) TCCTGGAA 1 chr9:101614069-101614149 ( 36) TCCCAGAA 1 chr6:53178699-53178779 ( 62) TCCCAGAA 1 chr1:22118088-22118168 ( 26) TCCCAGAA 1 chr12:32174020-32174100 ( 63) TCCCAGAA 1 chr2:28753816-28753896 ( 18) TCCCAGAA 1 chr7:100145711-100145791 ( 46) TCCCAGAA 1 chr19:17516531-17516611 ( 37) TCCCAGAA 1 chr2:231200768-231200848 ( 40) TCCCAGAA 1 chr20:36751436-36751516 ( 44) TCCCAGAA 1 chr11:65188828-65188908 ( 32) TCCGAGAA 1 chr2:231084689-231084769 ( 41) TCCGAGAA 1 chr18:43554213-43554293 ( 64) TCCGAGAA 1 chr4:185395890-185395970 ( 47) TCTCGGAA 1 chr10:3975328-3975408 ( 15) TCCAAGAA 1 chr21:45275152-45275232 ( 4) TCCAAGAA 1 chr15:45020978-45021058 ( 40) TCTCGGAA 1 chr2:120989942-120990022 ( 40) TCCAAGAA 1 chr5:149957855-149957935 ( 37) TCTGGGAA 1 chr7:116688668-116688748 ( 55) TCTGGGAA 1 chr16:3313886-3313966 ( 51) TCTGGGAA 1 chr2:240202051-240202131 ( 38) TCTGGGAA 1 chr1:152007201-152007281 ( 29) TCTGGGAA 1 chr6:42158721-42158801 ( 34) TCTGGGAA 1 chr14:24630360-24630440 ( 52) TCTGGGAA 1 chr2:74433412-74433492 ( 58) TCTGGGAA 1 chrX:40869487-40869567 ( 46) TCCTAGAA 1 chr1:113480991-113481071 ( 17) TCTAGGAA 1 chr2:97151892-97151972 ( 57) TCTAGGAA 1 chr16:11406643-11406723 ( 45) TCTTGGAA 1 chrX:138295709-138295789 ( 59) TCTCAGAA 1 chr14:100841767-10084184 ( 52) TCTCAGAA 1 chr13:43566399-43566479 ( 27) TCTCAGAA 1 chr4:169239939-169240019 ( 26) TCTCAGAA 1 chr12:104995195-10499527 ( 52) TCTCAGAA 1 chr6:126244562-126244642 ( 42) TCCCGTAA 1 chr1:6464831-6464911 ( 21) TCCCGTAA 1 chr11:5710949-5711029 ( 23) TCTGAGAA 1 chr6:138043957-138044037 ( 41) TCTGAGAA 1 chr11:313965-314045 ( 64) TCTGAGAA 1 chr9:33081350-33081430 ( 48) TCCGGTAA 1 chr2:20776597-20776677 ( 42) TCTAAGAA 1 chr17:41158728-41158808 ( 52) TCACGGAA 1 chr15:57029724-57029804 ( 36) TCTAAGAA 1 chr14:97297399-97297479 ( 42) TCTAAGAA 1 chr17:57863954-57864034 ( 56) TCCAGTAA 1 chr8:8864277-8864357 ( 61) TCCAGTAA 1 chr6:36315524-36315604 ( 48) TCAGGGAA 1 chrX:48794449-48794529 ( 66) TCTTAGAA 1 chrX:154564131-154564211 ( 73) TCCTGTAA 1 chr7:105924488-105924568 ( 69) TCCTGTAA 1 chr2:202084933-202085013 ( 30) TCAAGGAA 1 chr5:119848599-119848679 ( 45) TCCTGTAA 1 chr21:38791958-38792038 ( 21) TCCTGTAA 1 chr4:38285521-38285601 ( 42) TCAAGGAA 1 chr1:110453391-110453471 ( 20) TCCCATAA 1 chr3:177332885-177332965 ( 34) TCCCTGAA 1 chr6:16237011-16237091 ( 24) TCCCTGAA 1 chr20:388956-389036 ( 39) TCCCGGGA 1 chr15:75417763-75417843 ( 51) TCACAGAA 1 chr4:17578595-17578675 ( 51) TCCCGGGA 1 chr11:615632-615712 ( 56) TCCCGGGA 1 chr6:119634242-119634322 ( 51) TACGGGAA 1 chr2:216696251-216696331 ( 54) TCAGAGAA 1 chr8:10488036-10488116 ( 63) TCAGAGAA 1 chr6:30457084-30457164 ( 55) TCTCGTAA 1 chr3:172230374-172230454 ( 35) TACGGGAA 1 chr2:201248606-201248686 ( 45) TCAGAGAA 1 chr6:43597860-43597940 ( 25) GCCGGGAA 1 chr12:56754195-56754275 ( 51) CCCCGGAA 1 chr3:122283123-122283203 ( 25) GCCGGGAA 1 chr4:78656214-78656294 ( 66) TCCAGGGA 1 chr19:51727739-51727819 ( 2) TCCTTGAA 1 chr2:38701190-38701270 ( 35) TCCTTGAA 1 chr2:7017754-7017834 ( 60) TCAAAGAA 1 chrX:154014325-154014405 ( 30) GCCAGGAA 1 chr2:178107363-178107443 ( 16) TACTGGAA 1 chr11:78356415-78356495 ( 65) CCCAGGAA 1 chr14:97284354-97284434 ( 39) CCCAGGAA 1 chr19:47760201-47760281 ( 7) TACTGGAA 1 chr6:100706024-100706104 ( 64) TCTTGTAA 1 chr19:1132298-1132378 ( 26) TTCAGGAA 1 chr20:35579209-35579289 ( 44) TTCAGGAA 1 chr16:17922035-17922115 ( 21) TCTCATAA 1 chr9:32526255-32526335 ( 13) TCCGAGGA 1 chr2:231280823-231280903 ( 8) GCCCAGAA 1 chr7:92634374-92634454 ( 44) TCTGATAA 1 chr6:42013470-42013550 ( 68) CCCCAGAA 1 chr7:36444533-36444613 ( 9) TTCTGGAA 1 chr22:50978142-50978222 ( 9) TCTGATAA 1 chr18:2641788-2641868 ( 30) TCTGATAA 1 chr15:81400313-81400393 ( 37) TCTGTGAA 1 chr1:44514057-44514137 ( 54) TATGGGAA 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCCNGGAA MEME-1 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 7.83461 E= 2.4e-087 -1379 -313 -311 184 -281 193 -1379 -364 -196 151 -1379 -18 -13 33 18 -47 23 -1379 148 -290 -1379 -1379 187 -123 197 -1379 -278 -1379 202 -1379 -1379 -1379 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCCNGGAA MEME-1 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 142 E= 2.4e-087 0.000000 0.028169 0.028169 0.943662 0.035211 0.943662 0.000000 0.021127 0.063380 0.704225 0.000000 0.232394 0.225352 0.309859 0.274648 0.190141 0.288732 0.000000 0.676056 0.035211 0.000000 0.000000 0.887324 0.112676 0.964789 0.000000 0.035211 0.000000 1.000000 0.000000 0.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCCNGGAA MEME-1 regular expression -------------------------------------------------------------------------------- TC[CT][CGA][GA]GAA -------------------------------------------------------------------------------- Time 4.75 secs. ******************************************************************************** ******************************************************************************** MOTIF TCAGTTTC MEME-2 width = 8 sites = 89 llr = 696 E-value = 1.1e-046 ******************************************************************************** -------------------------------------------------------------------------------- Motif TCAGTTTC MEME-2 Description -------------------------------------------------------------------------------- Simplified A :15::::: pos.-specific C :622:::a probability G ::17:::: matrix T a311aaa: bits 2.0 * 1.8 * **** 1.6 * **** 1.4 * **** Relative 1.2 * **** Entropy 1.0 * **** (11.3 bits) 0.8 * ***** 0.6 ** ***** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel TCAGTTTC consensus TCC sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCAGTTTC MEME-2 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr16:48642597-48642677 48 1.78e-05 ACTTTGAGTT TCAGTTTC CCCAGCTGtt chr17:30454490-30454570 27 1.78e-05 CTCATCTAGA TCAGTTTC GATTCCCGCT chr16:3313886-3313966 21 1.78e-05 tcgatttttc tcagtttc catttcctat chr20:62205543-62205623 36 1.78e-05 CCAGGAGCTC TCAGTTTC GATTCTGGCC chr15:52024148-52024228 43 1.78e-05 CCAAGTAGTT TCAGTTTC CCAGACCCAC chr11:64764505-64764585 5 1.78e-05 AGTT TCAGTTTC TCCTAAAGCC chr10:25156323-25156403 14 1.78e-05 TTCCCTCTTG TCAGTTTC ATTTTCCTAA chr21:35029618-35029698 8 1.78e-05 CTGATTG TCAGTTTC CTCTTAGTTT chr19:17516531-17516611 25 1.78e-05 AATTAGGTTT TCAGTTTC AGTTTCCCAG chr2:37384094-37384174 22 1.78e-05 GAGCTGGTTC TCAGTTTC GTTTTCCCCT chr3:48514483-48514563 10 1.78e-05 GTGGGCCAC TCAGTTTC AATTTCCTCC chr2:7017754-7017834 11 1.78e-05 GTTTCAACTT TCAGTTTC ACATGTGGAA chr4:169239939-169240019 45 1.78e-05 CACTTAGGTT TCAGTTTC CCTTCAGCAC chr8:144107938-144108018 26 1.78e-05 AGTTTCAGTT TCAGTTTC CTGGTACATC chr4:17578595-17578675 39 1.78e-05 GCTCTGGCAC TCAGTTTC TATTTCCCGG chr18:2641788-2641868 38 1.78e-05 TTTCTGATAA TCAGTTTC ATTTCTTCAT chr10:91092176-91092256 55 1.78e-05 TAGGGTTCCA TCAGTTTC ACTTTCCTTT chr7:92747397-92747477 24 1.78e-05 AGGTTTGGTT TCAGTTTC ATTTCTCAGA chr11:4414904-4414984 4 1.78e-05 CTT TCAGTTTC CGCTCAGAAG chr12:121477036-12147711 18 1.78e-05 CAATCTGTCA TCAGTTTC GATTCTCAAC chr18:60173635-60173715 23 1.78e-05 TGGCTAAGTT TCAGTTTC GTTTCATTTT chr10:91174282-91174362 41 1.78e-05 TTCTTAAGTT TCAGTTTC TGAGCGCTCG chr4:89300514-89300594 17 1.78e-05 AGCAACTTCC TCAGTTTC GTTTTCCCAA chr2:86811361-86811441 4 3.68e-05 ctg ttagtttc ctttctctca chr7:2445739-2445819 66 3.68e-05 AGAGTAGCTG TTAGTTTC ACACTTG chr12:50665870-50665950 4 3.68e-05 TTC TTAGTTTC ACTTCTGGAC chr7:92776946-92777026 22 3.68e-05 CACAAGCAAG TTAGTTTC GTTTTCCTGA chr10:91087612-91087692 16 3.68e-05 CGATTTTAAA TTAGTTTC ACTTTCCAGT chr6:99281972-99282052 34 5.46e-05 CCTTACCCCC TCCGTTTC CCCATCTTAA chr15:81400313-81400393 25 5.46e-05 tctctgcact tccgtttc ctcgtctgtg chr1:113480991-113481071 28 7.27e-05 CTAGGAAACC TCACTTTC GTTTCTTTTC chr8:10488036-10488116 27 7.27e-05 GGTTTCACTT TCACTTTC TGTTTCCCAG chr14:97284354-97284434 9 7.27e-05 TGTCTTCA TCACTTTC GTTTCTGGGA chr3:36949602-36949682 23 7.27e-05 CCTCTATGTT TCACTTTC TATTTCCCTT chr16:11406643-11406723 33 7.27e-05 TTCTCTGGTT TCACTTTC AGTTTCTTGG chr2:152146439-152146519 7 7.27e-05 CTAATT TCACTTTC GATTTTTAAA chr11:5646130-5646210 13 7.27e-05 CCCAAAAATT TCACTTTC ATTTCTCAGG chr2:20776597-20776677 10 9.17e-05 GTTTCTGTT TCTGTTTC GGTTACGTAT chr10:3975328-3975408 42 9.17e-05 CAGTTAGCTT TCTGTTTC CTTTCCCAAG chr9:108641637-108641717 14 9.17e-05 tcttatcttc tctgtttc acttccccac chr2:163175196-163175276 12 9.17e-05 GACTTTGGTT TCTGTTTC GATTCTCTTC chr1:25682520-25682600 62 9.17e-05 ctaactggtt tctgtttc ctctcttgcc chr2:55921012-55921092 25 1.11e-04 CTGATGGAGT TTCGTTTC CGCGGTGCCC chr11:5710949-5711029 38 1.11e-04 GAATTTAACT TTCGTTTC TCACTCAGCT chr5:39077199-39077279 42 1.11e-04 CTTCTTAGTT TTCGTTTC CCAGCTAGGT chr3:146262417-146262497 15 1.11e-04 GGCTCCTGGT TTCGTTTC CTGAATCTTA chr3:172312543-172312623 30 1.11e-04 GAAGTGAACT TTCGTTTC TCCTGTTCTC chr1:154580665-154580745 7 1.11e-04 TTCGCT TTCGTTTC CTCGGAAAGC chr8:144105606-144105686 73 1.11e-04 AGAGCCTCGT TTCGTTTC chr1:185303423-185303503 22 1.11e-04 CATTGTAAGT TTCGTTTC TGGTTGAGGC chr15:92015887-92015967 3 1.11e-04 gt ttcgtttc tctagggtaa chr5:10627856-10627936 38 1.28e-04 TTGGTGAGTC TCGGTTTC CCAGCGTTGC chr10:91152276-91152356 3 1.28e-04 TT TCGGTTTC CCTAGGTTTC chr5:131832712-131832792 7 1.28e-04 TGGGTT TCGGTTTC TTGCAAACGC chr1:158979613-158979693 11 1.48e-04 AGGAAACTGT TCATTTTC TCTGACTAAC chr4:185395890-185395970 64 1.48e-04 AAAGTCAATT TCATTTTC GCTTCCCCA chr7:105924488-105924568 48 1.48e-04 TCCTCGTGTT TCATTTTC CTTTTCACAG chr1:27998785-27998865 67 1.48e-04 CTGCAGAGTT TCATTTTC CCCTCT chr21:38791958-38792038 9 1.67e-04 CACTGAGA TTACTTTC ATTTTCCTGT chr1:948708-948788 21 2.05e-04 GTCATTCGGT TTTGTTTC TTCCGCTCAC chr1:54842892-54842972 37 2.05e-04 ACGGTGCTCC TCCCTTTC CCCACAAGGT chr2:202084933-202085013 8 2.05e-04 ttccagt tccctttc tagcctcatg chr15:57029724-57029804 15 2.05e-04 ttccgtaagt tccctttc tgctccttcc chr22:18632813-18632893 10 2.23e-04 AGGCCGCTG TAAGTTTC GCTTTCCATT chr6:16237011-16237091 9 2.23e-04 CTCTCTGA TAAGTTTC ATTTCCTTCC chr3:5191305-5191385 15 2.23e-04 cttccccact taagtttc gatttcccaa chr2:152118323-152118403 7 2.59e-04 CAGGTT TTGGTTTC GTTTTTTGTT chr13:43566399-43566479 15 2.59e-04 TTTTAACAGC TGAGTTTC GGTTTCTCAG chr7:120640183-120640263 17 2.59e-04 AAGGAATGTT TTGGTTTC GTTTTCCCCC chr1:8812665-8812745 46 2.59e-04 TAAAACCTTG TGAGTTTC TTTTCCTATG chr7:116688668-116688748 17 2.99e-04 atatctgcgg tctctttc atggtttcct chr2:99176946-99177026 59 2.99e-04 CTTCACAGTT TCTCTTTC CCCAAAAGTC chr7:87834657-87834737 35 3.19e-04 acatattatc tccttttc aaagatgggg chr21:42792447-42792527 20 3.38e-04 AATTTGACTT TTCCTTTC TGGAAACCAG chr20:36751436-36751516 3 3.38e-04 ga ttcctttc ttctgagtgt chr8:20060062-20060142 53 3.94e-04 GACTAGTGTT TCTTTTTC TTGGTCATAC chr10:3871190-3871270 15 4.32e-04 TGGGTAATTC TTTCTTTC CCTTTAAACT chr1:173640228-173640308 56 4.32e-04 atgacaaaac tttctttc cttttatgga chr1:22118088-22118168 68 4.71e-04 ccttagaggg taactttc agatg chr8:26150630-26150710 5 4.71e-04 CGGT TTCTTTTC CTCTCTGTCT chr4:169401688-169401768 3 4.71e-04 GT TTCTTTTC TCCACCGCGA chr10:25026137-25026217 13 4.71e-04 cttatctgag ttcttttc ttaagaaatc chr6:30457084-30457164 40 5.25e-04 GGGAAACTCT GCAGTTTC CCGTTCCTCT chr14:94576944-94577024 26 5.25e-04 AAAGATGTCT GCAGTTTC GGTTTCCTGG chrX:40869487-40869567 66 5.81e-04 ccctccctgc tgtgtttc cgggtta chr15:43398349-43398429 61 6.20e-04 CTGGAGATTT TTTTTTTC CCCTCTAATT chr1:169337688-169337768 27 6.20e-04 GGATGAAACT TAGGTTTC GACTTCCCCG chr6:47382628-47382708 10 6.20e-04 TTGTGTGAT TAGGTTTC GTTTTACTGT chr10:114851848-11485192 34 6.75e-04 ACAGAAAGAC TGGGTTTC TTCCTTATAA -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCAGTTTC MEME-2 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr16:48642597-48642677 1.8e-05 47_[+2]_25 chr17:30454490-30454570 1.8e-05 26_[+2]_46 chr16:3313886-3313966 1.8e-05 20_[+2]_52 chr20:62205543-62205623 1.8e-05 35_[+2]_37 chr15:52024148-52024228 1.8e-05 42_[+2]_30 chr11:64764505-64764585 1.8e-05 4_[+2]_68 chr10:25156323-25156403 1.8e-05 13_[+2]_59 chr21:35029618-35029698 1.8e-05 7_[+2]_65 chr19:17516531-17516611 1.8e-05 24_[+2]_48 chr2:37384094-37384174 1.8e-05 21_[+2]_51 chr3:48514483-48514563 1.8e-05 9_[+2]_63 chr2:7017754-7017834 1.8e-05 10_[+2]_62 chr4:169239939-169240019 1.8e-05 44_[+2]_28 chr8:144107938-144108018 1.8e-05 25_[+2]_47 chr4:17578595-17578675 1.8e-05 38_[+2]_34 chr18:2641788-2641868 1.8e-05 37_[+2]_35 chr10:91092176-91092256 1.8e-05 54_[+2]_18 chr7:92747397-92747477 1.8e-05 23_[+2]_49 chr11:4414904-4414984 1.8e-05 3_[+2]_69 chr12:121477036-12147711 1.8e-05 17_[+2]_55 chr18:60173635-60173715 1.8e-05 22_[+2]_50 chr10:91174282-91174362 1.8e-05 40_[+2]_32 chr4:89300514-89300594 1.8e-05 16_[+2]_56 chr2:86811361-86811441 3.7e-05 3_[+2]_69 chr7:2445739-2445819 3.7e-05 65_[+2]_7 chr12:50665870-50665950 3.7e-05 3_[+2]_69 chr7:92776946-92777026 3.7e-05 21_[+2]_51 chr10:91087612-91087692 3.7e-05 15_[+2]_57 chr6:99281972-99282052 5.5e-05 33_[+2]_39 chr15:81400313-81400393 5.5e-05 24_[+2]_48 chr1:113480991-113481071 7.3e-05 27_[+2]_45 chr8:10488036-10488116 7.3e-05 26_[+2]_46 chr14:97284354-97284434 7.3e-05 8_[+2]_64 chr3:36949602-36949682 7.3e-05 22_[+2]_50 chr16:11406643-11406723 7.3e-05 32_[+2]_40 chr2:152146439-152146519 7.3e-05 6_[+2]_66 chr11:5646130-5646210 7.3e-05 12_[+2]_60 chr2:20776597-20776677 9.2e-05 9_[+2]_63 chr10:3975328-3975408 9.2e-05 41_[+2]_31 chr9:108641637-108641717 9.2e-05 13_[+2]_59 chr2:163175196-163175276 9.2e-05 11_[+2]_61 chr1:25682520-25682600 9.2e-05 61_[+2]_11 chr2:55921012-55921092 0.00011 24_[+2]_48 chr11:5710949-5711029 0.00011 37_[+2]_35 chr5:39077199-39077279 0.00011 41_[+2]_31 chr3:146262417-146262497 0.00011 14_[+2]_58 chr3:172312543-172312623 0.00011 29_[+2]_43 chr1:154580665-154580745 0.00011 6_[+2]_66 chr8:144105606-144105686 0.00011 72_[+2] chr1:185303423-185303503 0.00011 21_[+2]_51 chr15:92015887-92015967 0.00011 2_[+2]_70 chr5:10627856-10627936 0.00013 37_[+2]_35 chr10:91152276-91152356 0.00013 2_[+2]_70 chr5:131832712-131832792 0.00013 6_[+2]_66 chr1:158979613-158979693 0.00015 10_[+2]_62 chr4:185395890-185395970 0.00015 63_[+2]_9 chr7:105924488-105924568 0.00015 47_[+2]_25 chr1:27998785-27998865 0.00015 66_[+2]_6 chr21:38791958-38792038 0.00017 8_[+2]_64 chr1:948708-948788 0.00021 20_[+2]_52 chr1:54842892-54842972 0.00021 36_[+2]_36 chr2:202084933-202085013 0.00021 7_[+2]_65 chr15:57029724-57029804 0.00021 14_[+2]_58 chr22:18632813-18632893 0.00022 9_[+2]_63 chr6:16237011-16237091 0.00022 8_[+2]_64 chr3:5191305-5191385 0.00022 14_[+2]_58 chr2:152118323-152118403 0.00026 6_[+2]_66 chr13:43566399-43566479 0.00026 14_[+2]_58 chr7:120640183-120640263 0.00026 16_[+2]_56 chr1:8812665-8812745 0.00026 45_[+2]_27 chr7:116688668-116688748 0.0003 16_[+2]_56 chr2:99176946-99177026 0.0003 58_[+2]_14 chr7:87834657-87834737 0.00032 34_[+2]_38 chr21:42792447-42792527 0.00034 19_[+2]_53 chr20:36751436-36751516 0.00034 2_[+2]_70 chr8:20060062-20060142 0.00039 52_[+2]_20 chr10:3871190-3871270 0.00043 14_[+2]_58 chr1:173640228-173640308 0.00043 55_[+2]_17 chr1:22118088-22118168 0.00047 67_[+2]_5 chr8:26150630-26150710 0.00047 4_[+2]_68 chr4:169401688-169401768 0.00047 2_[+2]_70 chr10:25026137-25026217 0.00047 12_[+2]_60 chr6:30457084-30457164 0.00053 39_[+2]_33 chr14:94576944-94577024 0.00053 25_[+2]_47 chrX:40869487-40869567 0.00058 65_[+2]_7 chr15:43398349-43398429 0.00062 60_[+2]_12 chr1:169337688-169337768 0.00062 26_[+2]_46 chr6:47382628-47382708 0.00062 9_[+2]_63 chr10:114851848-11485192 0.00068 33_[+2]_39 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCAGTTTC MEME-2 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF TCAGTTTC width=8 seqs=89 chr16:48642597-48642677 ( 48) TCAGTTTC 1 chr17:30454490-30454570 ( 27) TCAGTTTC 1 chr16:3313886-3313966 ( 21) TCAGTTTC 1 chr20:62205543-62205623 ( 36) TCAGTTTC 1 chr15:52024148-52024228 ( 43) TCAGTTTC 1 chr11:64764505-64764585 ( 5) TCAGTTTC 1 chr10:25156323-25156403 ( 14) TCAGTTTC 1 chr21:35029618-35029698 ( 8) TCAGTTTC 1 chr19:17516531-17516611 ( 25) TCAGTTTC 1 chr2:37384094-37384174 ( 22) TCAGTTTC 1 chr3:48514483-48514563 ( 10) TCAGTTTC 1 chr2:7017754-7017834 ( 11) TCAGTTTC 1 chr4:169239939-169240019 ( 45) TCAGTTTC 1 chr8:144107938-144108018 ( 26) TCAGTTTC 1 chr4:17578595-17578675 ( 39) TCAGTTTC 1 chr18:2641788-2641868 ( 38) TCAGTTTC 1 chr10:91092176-91092256 ( 55) TCAGTTTC 1 chr7:92747397-92747477 ( 24) TCAGTTTC 1 chr11:4414904-4414984 ( 4) TCAGTTTC 1 chr12:121477036-12147711 ( 18) TCAGTTTC 1 chr18:60173635-60173715 ( 23) TCAGTTTC 1 chr10:91174282-91174362 ( 41) TCAGTTTC 1 chr4:89300514-89300594 ( 17) TCAGTTTC 1 chr2:86811361-86811441 ( 4) TTAGTTTC 1 chr7:2445739-2445819 ( 66) TTAGTTTC 1 chr12:50665870-50665950 ( 4) TTAGTTTC 1 chr7:92776946-92777026 ( 22) TTAGTTTC 1 chr10:91087612-91087692 ( 16) TTAGTTTC 1 chr6:99281972-99282052 ( 34) TCCGTTTC 1 chr15:81400313-81400393 ( 25) TCCGTTTC 1 chr1:113480991-113481071 ( 28) TCACTTTC 1 chr8:10488036-10488116 ( 27) TCACTTTC 1 chr14:97284354-97284434 ( 9) TCACTTTC 1 chr3:36949602-36949682 ( 23) TCACTTTC 1 chr16:11406643-11406723 ( 33) TCACTTTC 1 chr2:152146439-152146519 ( 7) TCACTTTC 1 chr11:5646130-5646210 ( 13) TCACTTTC 1 chr2:20776597-20776677 ( 10) TCTGTTTC 1 chr10:3975328-3975408 ( 42) TCTGTTTC 1 chr9:108641637-108641717 ( 14) TCTGTTTC 1 chr2:163175196-163175276 ( 12) TCTGTTTC 1 chr1:25682520-25682600 ( 62) TCTGTTTC 1 chr2:55921012-55921092 ( 25) TTCGTTTC 1 chr11:5710949-5711029 ( 38) TTCGTTTC 1 chr5:39077199-39077279 ( 42) TTCGTTTC 1 chr3:146262417-146262497 ( 15) TTCGTTTC 1 chr3:172312543-172312623 ( 30) TTCGTTTC 1 chr1:154580665-154580745 ( 7) TTCGTTTC 1 chr8:144105606-144105686 ( 73) TTCGTTTC 1 chr1:185303423-185303503 ( 22) TTCGTTTC 1 chr15:92015887-92015967 ( 3) TTCGTTTC 1 chr5:10627856-10627936 ( 38) TCGGTTTC 1 chr10:91152276-91152356 ( 3) TCGGTTTC 1 chr5:131832712-131832792 ( 7) TCGGTTTC 1 chr1:158979613-158979693 ( 11) TCATTTTC 1 chr4:185395890-185395970 ( 64) TCATTTTC 1 chr7:105924488-105924568 ( 48) TCATTTTC 1 chr1:27998785-27998865 ( 67) TCATTTTC 1 chr21:38791958-38792038 ( 9) TTACTTTC 1 chr1:948708-948788 ( 21) TTTGTTTC 1 chr1:54842892-54842972 ( 37) TCCCTTTC 1 chr2:202084933-202085013 ( 8) TCCCTTTC 1 chr15:57029724-57029804 ( 15) TCCCTTTC 1 chr22:18632813-18632893 ( 10) TAAGTTTC 1 chr6:16237011-16237091 ( 9) TAAGTTTC 1 chr3:5191305-5191385 ( 15) TAAGTTTC 1 chr2:152118323-152118403 ( 7) TTGGTTTC 1 chr13:43566399-43566479 ( 15) TGAGTTTC 1 chr7:120640183-120640263 ( 17) TTGGTTTC 1 chr1:8812665-8812745 ( 46) TGAGTTTC 1 chr7:116688668-116688748 ( 17) TCTCTTTC 1 chr2:99176946-99177026 ( 59) TCTCTTTC 1 chr7:87834657-87834737 ( 35) TCCTTTTC 1 chr21:42792447-42792527 ( 20) TTCCTTTC 1 chr20:36751436-36751516 ( 3) TTCCTTTC 1 chr8:20060062-20060142 ( 53) TCTTTTTC 1 chr10:3871190-3871270 ( 15) TTTCTTTC 1 chr1:173640228-173640308 ( 56) TTTCTTTC 1 chr1:22118088-22118168 ( 68) TAACTTTC 1 chr8:26150630-26150710 ( 5) TTCTTTTC 1 chr4:169401688-169401768 ( 3) TTCTTTTC 1 chr10:25026137-25026217 ( 13) TTCTTTTC 1 chr6:30457084-30457164 ( 40) GCAGTTTC 1 chr14:94576944-94577024 ( 26) GCAGTTTC 1 chrX:40869487-40869567 ( 66) TGTGTTTC 1 chr15:43398349-43398429 ( 61) TTTTTTTC 1 chr1:169337688-169337768 ( 27) TAGGTTTC 1 chr6:47382628-47382708 ( 10) TAGGTTTC 1 chr10:114851848-11485192 ( 34) TGGGTTTC 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCAGTTTC MEME-2 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 9.21773 E= 1.1e-046 -1312 -1312 -343 189 -187 127 -243 15 113 -14 -143 -85 -1312 -29 150 -123 -1312 -1312 -1312 192 -1312 -1312 -1312 192 -1312 -1312 -1312 192 -1312 202 -1312 -1312 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCAGTTTC MEME-2 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 89 E= 1.1e-046 0.000000 0.000000 0.022472 0.977528 0.067416 0.595506 0.044944 0.292135 0.539326 0.224719 0.089888 0.146067 0.000000 0.202247 0.685393 0.112360 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCAGTTTC MEME-2 regular expression -------------------------------------------------------------------------------- T[CT][AC][GC]TTTC -------------------------------------------------------------------------------- Time 8.21 secs. ******************************************************************************** ******************************************************************************** MOTIF AAVYGAAA MEME-3 width = 8 sites = 66 llr = 545 E-value = 5.5e-035 ******************************************************************************** -------------------------------------------------------------------------------- Motif AAVYGAAA MEME-3 Description -------------------------------------------------------------------------------- Simplified A aa411aaa pos.-specific C ::24:::: probability G ::319::: matrix T ::13:::: bits 2.0 ** * * 1.8 ** *** 1.6 ** **** 1.4 ** **** Relative 1.2 ** **** Entropy 1.0 ** **** (11.9 bits) 0.8 ** **** 0.6 ** **** 0.4 ** **** 0.2 ******** 0.0 -------- Multilevel AAACGAAA consensus GT sequence C -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAVYGAAA MEME-3 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr1:158979613-158979693 31 1.36e-05 TGACTAACAG AAACGAAA GCTAAAAACA chr2:75538120-75538200 67 1.36e-05 TTTCGCAAAA AAACGAAA CTAAAC chr22:18632813-18632893 35 1.36e-05 ATTCAGTGGA AAACGAAA GCTGGGCGGG chrX:41190885-41190965 69 1.36e-05 GTTCATAGGA AAACGAAA CTGA chr13:50070001-50070081 63 1.36e-05 AGATTTAAGA AAACGAAA CCTAGTGCAG chr6:99281972-99282052 64 1.36e-05 CCCTATTGGG AAACGAAA GTGGACACC chr17:26595403-26595483 59 1.36e-05 acactcagga aaacgaaa cctaactaac chr2:7005885-7005965 72 1.36e-05 CGTTGCGGGG AAACGAAA G chr7:134832719-134832799 48 1.36e-05 GCAAGTTAGG AAACGAAA GTGAAATCAG chr6:100706024-100706104 40 1.36e-05 AAAAAGAGGA AAACGAAA GGCTATAAGG chr12:113376105-11337618 27 1.36e-05 TGCTAGAAAG AAACGAAA CTGAAAGCAG chr12:113344699-11334477 52 1.36e-05 CCTTCTGAGG AAACGAAA CCAACAGCAG chr19:10196907-10196987 45 2.70e-05 CCTGAATCGA AAGCGAAA CAGGGGCCGG chr7:74064475-74064555 44 2.70e-05 aaactgcaga aagcgaaa ctgcagataa chr6:32821581-32821661 21 2.70e-05 ATTTAGGGGA AAGCGAAA TCGAAAGCGG chr11:615632-615712 64 2.70e-05 GCTCCCGGGA AAGCGAAA CCTAAACAG chr3:122399598-122399678 61 2.70e-05 CAGGAAACGA AAGCGAAA GAGTCAAAGT chr4:89300514-89300594 73 2.70e-05 TTCAAGTTCA AAGCGAAA chr3:122283123-122283203 52 2.70e-05 ACCTCCAGGG AAGCGAAA CTGAAACTTT chr10:114851848-11485192 17 4.16e-05 AGTATGAGGA AAATGAAA CAGAAAGACT chr6:168241706-168241786 32 4.16e-05 GGGAAGGAGA AAATGAAA CTGAAGGAGG chr21:42792447-42792527 45 4.16e-05 CAGCGAGCAG AAATGAAA CCGAAACTGA chr11:57333727-57333807 65 4.16e-05 GAGGAACAGA AAATGAAA GTAGAAAG chr9:90289670-90289750 65 6.96e-05 TCTGATGAGA AAGTGAAA GCTAAGTT chr9:100881488-100881568 35 6.96e-05 TCCCAAGGGA AACCGAAA CCTCGGCCGT chr1:948708-948788 64 6.96e-05 GGGAAAGGGA AACCGAAA CTGAAGCCA chr10:80719153-80719233 63 6.96e-05 cagatgagga aagtgaaa cctaggatgt chr22:36044411-36044491 72 6.96e-05 TGCAGCACTT AACCGAAA C chr7:36444533-36444613 70 6.96e-05 gaaactggga aagtgaaa ctg chr20:35579209-35579289 72 6.96e-05 tcagggagga aaccgaaa c chr2:201248606-201248686 57 6.96e-05 AGAGAAACGA AAGTGAAA CTTTATTACT chr2:231084689-231084769 54 6.96e-05 GAGAAAAGAA AAGTGAAA GTTTTCGGAG chr8:90996283-90996363 14 8.41e-05 TCTGAAACAA AACTGAAA GTAAGCCTTT chr10:3871190-3871270 47 8.41e-05 TCAGAATCGA AACTGAAA CTAAGAAAAG chr1:21670071-21670151 53 8.41e-05 cagatgagga aactgaaa ctcaagggtg chr1:54842892-54842972 16 8.41e-05 CAAAACCCAA AACTGAAA CCCACGGTGC chr5:81763178-81763258 25 8.41e-05 TGACCTTTCC AACTGAAA CGCTGCTCCC chr7:87834657-87834737 54 8.41e-05 aagatgggga aactgaaa ctgggcatta chr4:38285521-38285601 33 8.41e-05 ctggtgagga aactgaaa ctcaaggaag chr17:40264716-40264796 26 8.41e-05 CAGAAATGGA AACTGAAA CTGAGGGGAG chr17:80408780-80408860 72 1.11e-04 TTTCTTGAAA AAAAGAAA C chr8:8864277-8864357 5 1.11e-04 CCTC AAAGGAAA TGGGTGAGTC chr19:51727739-51727819 24 1.11e-04 atgaggctag aaaggaaa ttggaactta chr19:48018762-48018842 51 1.11e-04 GTTTGTGGGA AAAGGAAA CCGTTCTGCT chr3:48514483-48514563 39 1.11e-04 CTTTTGGAGA AAAAGAAA GCAAATCTCC chr15:45020978-45021058 66 1.38e-04 GCTTTGAAGA AAGAGAAA CCAGGAC chr16:11391451-11391531 71 1.38e-04 CTTGACGGGA AAGAGAAA CT chr6:42013470-42013550 49 1.38e-04 TCAGCAGGGA AAGGGAAA CTTGGCAGGG chr11:313965-314045 48 1.38e-04 ATAGAAACTT AAGAGAAA TACACACTTC chr9:32526255-32526335 68 1.38e-04 TTAATAACTA AAGGGAAA ATCGA chr6:47382628-47382708 66 1.38e-04 AAAAACACCA AAGAGAAA GTTGCAA chr4:78656214-78656294 44 1.52e-04 tccaattaga aatcgaaa gcaaaagtta chr2:26716571-26716651 19 1.52e-04 gttattggga aatcgaaa cttaagtggg chr2:7017754-7017834 30 1.52e-04 CATGTGGAAA AATCGAAA CTCTAACTCA chr15:74287061-74287141 71 1.52e-04 CTAAACCGAG AATCGAAA CT chr2:55921012-55921092 58 1.79e-04 ACGCCGGGGT AACGGAAA CCTTGGCCAC chrX:154014325-154014405 63 1.79e-04 TTGGTTGAGA AACAGAAA CTACAAACAA chr10:25026137-25026217 46 1.95e-04 tcaggcaagg aattgaaa ctcttcagat chr1:44514057-44514137 40 2.37e-04 CAGAGTGGGG AAATAAAA GGGCTTTATG chr1:113480991-113481071 72 2.66e-04 ACATTGAGGA AACCAAAA C chr22:50978142-50978222 34 2.66e-04 tgtgaggcag aagtaaaa ctcaactcca chr12:117463514-11746359 31 3.36e-04 GCCAAACGGC AACTAAAA CTCCCGCACT chr5:142604444-142604524 60 3.36e-04 ACCCAGGAGC AAGCGAGA CACTACCATT chr6:138043957-138044037 27 3.50e-04 GTCAGGAAAT AAATGAGA CAGCATTCTG chr3:172230374-172230454 47 3.78e-04 CGGGAAGGGG AAGTGAGA GGAAACCACA chr6:119634242-119634322 62 4.20e-04 ACGGGAAAGG AAAGAAAA GAGGCTAATG -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAVYGAAA MEME-3 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr1:158979613-158979693 1.4e-05 30_[+3]_42 chr2:75538120-75538200 1.4e-05 66_[+3]_6 chr22:18632813-18632893 1.4e-05 34_[+3]_38 chrX:41190885-41190965 1.4e-05 68_[+3]_4 chr13:50070001-50070081 1.4e-05 62_[+3]_10 chr6:99281972-99282052 1.4e-05 63_[+3]_9 chr17:26595403-26595483 1.4e-05 58_[+3]_14 chr2:7005885-7005965 1.4e-05 71_[+3]_1 chr7:134832719-134832799 1.4e-05 47_[+3]_25 chr6:100706024-100706104 1.4e-05 39_[+3]_33 chr12:113376105-11337618 1.4e-05 26_[+3]_46 chr12:113344699-11334477 1.4e-05 51_[+3]_21 chr19:10196907-10196987 2.7e-05 44_[+3]_28 chr7:74064475-74064555 2.7e-05 43_[+3]_29 chr6:32821581-32821661 2.7e-05 20_[+3]_52 chr11:615632-615712 2.7e-05 63_[+3]_9 chr3:122399598-122399678 2.7e-05 60_[+3]_12 chr4:89300514-89300594 2.7e-05 72_[+3] chr3:122283123-122283203 2.7e-05 51_[+3]_21 chr10:114851848-11485192 4.2e-05 16_[+3]_56 chr6:168241706-168241786 4.2e-05 31_[+3]_41 chr21:42792447-42792527 4.2e-05 44_[+3]_28 chr11:57333727-57333807 4.2e-05 64_[+3]_8 chr9:90289670-90289750 7e-05 64_[+3]_8 chr9:100881488-100881568 7e-05 34_[+3]_38 chr1:948708-948788 7e-05 63_[+3]_9 chr10:80719153-80719233 7e-05 62_[+3]_10 chr22:36044411-36044491 7e-05 71_[+3]_1 chr7:36444533-36444613 7e-05 69_[+3]_3 chr20:35579209-35579289 7e-05 71_[+3]_1 chr2:201248606-201248686 7e-05 56_[+3]_16 chr2:231084689-231084769 7e-05 53_[+3]_19 chr8:90996283-90996363 8.4e-05 13_[+3]_59 chr10:3871190-3871270 8.4e-05 46_[+3]_26 chr1:21670071-21670151 8.4e-05 52_[+3]_20 chr1:54842892-54842972 8.4e-05 15_[+3]_57 chr5:81763178-81763258 8.4e-05 24_[+3]_48 chr7:87834657-87834737 8.4e-05 53_[+3]_19 chr4:38285521-38285601 8.4e-05 32_[+3]_40 chr17:40264716-40264796 8.4e-05 25_[+3]_47 chr17:80408780-80408860 0.00011 71_[+3]_1 chr8:8864277-8864357 0.00011 4_[+3]_68 chr19:51727739-51727819 0.00011 23_[+3]_49 chr19:48018762-48018842 0.00011 50_[+3]_22 chr3:48514483-48514563 0.00011 38_[+3]_34 chr15:45020978-45021058 0.00014 65_[+3]_7 chr16:11391451-11391531 0.00014 70_[+3]_2 chr6:42013470-42013550 0.00014 48_[+3]_24 chr11:313965-314045 0.00014 47_[+3]_25 chr9:32526255-32526335 0.00014 67_[+3]_5 chr6:47382628-47382708 0.00014 65_[+3]_7 chr4:78656214-78656294 0.00015 43_[+3]_29 chr2:26716571-26716651 0.00015 18_[+3]_54 chr2:7017754-7017834 0.00015 29_[+3]_43 chr15:74287061-74287141 0.00015 70_[+3]_2 chr2:55921012-55921092 0.00018 57_[+3]_15 chrX:154014325-154014405 0.00018 62_[+3]_10 chr10:25026137-25026217 0.00019 45_[+3]_27 chr1:44514057-44514137 0.00024 39_[+3]_33 chr1:113480991-113481071 0.00027 71_[+3]_1 chr22:50978142-50978222 0.00027 33_[+3]_39 chr12:117463514-11746359 0.00034 30_[+3]_42 chr5:142604444-142604524 0.00034 59_[+3]_13 chr6:138043957-138044037 0.00035 26_[+3]_46 chr3:172230374-172230454 0.00038 46_[+3]_26 chr6:119634242-119634322 0.00042 61_[+3]_11 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAVYGAAA MEME-3 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF AAVYGAAA width=8 seqs=66 chr1:158979613-158979693 ( 31) AAACGAAA 1 chr2:75538120-75538200 ( 67) AAACGAAA 1 chr22:18632813-18632893 ( 35) AAACGAAA 1 chrX:41190885-41190965 ( 69) AAACGAAA 1 chr13:50070001-50070081 ( 63) AAACGAAA 1 chr6:99281972-99282052 ( 64) AAACGAAA 1 chr17:26595403-26595483 ( 59) AAACGAAA 1 chr2:7005885-7005965 ( 72) AAACGAAA 1 chr7:134832719-134832799 ( 48) AAACGAAA 1 chr6:100706024-100706104 ( 40) AAACGAAA 1 chr12:113376105-11337618 ( 27) AAACGAAA 1 chr12:113344699-11334477 ( 52) AAACGAAA 1 chr19:10196907-10196987 ( 45) AAGCGAAA 1 chr7:74064475-74064555 ( 44) AAGCGAAA 1 chr6:32821581-32821661 ( 21) AAGCGAAA 1 chr11:615632-615712 ( 64) AAGCGAAA 1 chr3:122399598-122399678 ( 61) AAGCGAAA 1 chr4:89300514-89300594 ( 73) AAGCGAAA 1 chr3:122283123-122283203 ( 52) AAGCGAAA 1 chr10:114851848-11485192 ( 17) AAATGAAA 1 chr6:168241706-168241786 ( 32) AAATGAAA 1 chr21:42792447-42792527 ( 45) AAATGAAA 1 chr11:57333727-57333807 ( 65) AAATGAAA 1 chr9:90289670-90289750 ( 65) AAGTGAAA 1 chr9:100881488-100881568 ( 35) AACCGAAA 1 chr1:948708-948788 ( 64) AACCGAAA 1 chr10:80719153-80719233 ( 63) AAGTGAAA 1 chr22:36044411-36044491 ( 72) AACCGAAA 1 chr7:36444533-36444613 ( 70) AAGTGAAA 1 chr20:35579209-35579289 ( 72) AACCGAAA 1 chr2:201248606-201248686 ( 57) AAGTGAAA 1 chr2:231084689-231084769 ( 54) AAGTGAAA 1 chr8:90996283-90996363 ( 14) AACTGAAA 1 chr10:3871190-3871270 ( 47) AACTGAAA 1 chr1:21670071-21670151 ( 53) AACTGAAA 1 chr1:54842892-54842972 ( 16) AACTGAAA 1 chr5:81763178-81763258 ( 25) AACTGAAA 1 chr7:87834657-87834737 ( 54) AACTGAAA 1 chr4:38285521-38285601 ( 33) AACTGAAA 1 chr17:40264716-40264796 ( 26) AACTGAAA 1 chr17:80408780-80408860 ( 72) AAAAGAAA 1 chr8:8864277-8864357 ( 5) AAAGGAAA 1 chr19:51727739-51727819 ( 24) AAAGGAAA 1 chr19:48018762-48018842 ( 51) AAAGGAAA 1 chr3:48514483-48514563 ( 39) AAAAGAAA 1 chr15:45020978-45021058 ( 66) AAGAGAAA 1 chr16:11391451-11391531 ( 71) AAGAGAAA 1 chr6:42013470-42013550 ( 49) AAGGGAAA 1 chr11:313965-314045 ( 48) AAGAGAAA 1 chr9:32526255-32526335 ( 68) AAGGGAAA 1 chr6:47382628-47382708 ( 66) AAGAGAAA 1 chr4:78656214-78656294 ( 44) AATCGAAA 1 chr2:26716571-26716651 ( 19) AATCGAAA 1 chr2:7017754-7017834 ( 30) AATCGAAA 1 chr15:74287061-74287141 ( 71) AATCGAAA 1 chr2:55921012-55921092 ( 58) AACGGAAA 1 chrX:154014325-154014405 ( 63) AACAGAAA 1 chr10:25026137-25026217 ( 46) AATTGAAA 1 chr1:44514057-44514137 ( 40) AAATAAAA 1 chr1:113480991-113481071 ( 72) AACCAAAA 1 chr22:50978142-50978222 ( 34) AAGTAAAA 1 chr12:117463514-11746359 ( 31) AACTAAAA 1 chr5:142604444-142604524 ( 60) AAGCGAGA 1 chr6:138043957-138044037 ( 27) AAATGAGA 1 chr3:172230374-172230454 ( 47) AAGTGAGA 1 chr6:119634242-119634322 ( 62) AAAGAAAA 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAVYGAAA MEME-3 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 8.87455 E= 5.5e-035 202 -1269 -1269 -1269 202 -1269 -1269 -1269 56 -3 39 -180 -122 83 -119 40 -170 -1269 193 -1269 202 -1269 -1269 -1269 195 -1269 -241 -1269 202 -1269 -1269 -1269 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAVYGAAA MEME-3 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 66 E= 5.5e-035 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.363636 0.242424 0.318182 0.075758 0.106061 0.439394 0.106061 0.348485 0.075758 0.000000 0.924242 0.000000 1.000000 0.000000 0.000000 0.000000 0.954545 0.000000 0.045455 0.000000 1.000000 0.000000 0.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAVYGAAA MEME-3 regular expression -------------------------------------------------------------------------------- AA[AGC][CT]GAAA -------------------------------------------------------------------------------- Time 11.52 secs. ******************************************************************************** ******************************************************************************** MOTIF GGGAGGGG MEME-4 width = 8 sites = 54 llr = 429 E-value = 4.8e-013 ******************************************************************************** -------------------------------------------------------------------------------- Motif GGGAGGGG MEME-4 Description -------------------------------------------------------------------------------- Simplified A 1::6:131 pos.-specific C ::12:::: probability G 9a9:9879 matrix T :::211:: bits 2.0 * 1.8 * 1.6 ** * * 1.4 *** * * Relative 1.2 *** * ** Entropy 1.0 *** **** (11.5 bits) 0.8 *** **** 0.6 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel GGGAGGGG consensus C A sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GGGAGGGG MEME-4 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr11:65188828-65188908 45 1.24e-05 GAGAAGCACA GGGAGGGG TGCATGTCAG chr6:15097485-15097565 73 1.24e-05 GGACTTTCCA GGGAGGGG chr19:4540157-4540237 19 1.24e-05 GCAGGGGAAG GGGAGGGG TCAGGATTAC chr15:98619910-98619990 2 1.24e-05 A GGGAGGGG CCGTGCCTGT chr1:159047074-159047154 10 1.24e-05 gtaatcaag gggagggg ttttctggga chr5:119848599-119848679 34 1.24e-05 ctataataaa gggagggg atttcctgta chr1:158979613-158979693 54 3.73e-05 AAACACTGGT GGGAGGAG TCTCCACATT chr22:18632813-18632893 46 3.73e-05 AACGAAAGCT GGGCGGGG TGCCACGAGC chr9:100881488-100881568 16 3.73e-05 CCGGGACACA GGGCGGGG CTCCCAAGGG chr6:43597860-43597940 12 3.73e-05 ACCACCACGA GGGCGGGG CAGTGGCCGG chr12:12953556-12953636 65 3.73e-05 aaacacgctg gggaggag tggagtca chr6:10838826-10838906 58 3.73e-05 GCCTTCCCCG GGGCGGGG CTTCATGGAG chr8:144105606-144105686 6 3.73e-05 GAGAG GGGAGGAG CCCAGCGCCT chr11:4414904-4414984 61 3.73e-05 gaggagccgt gggaggag tgagggagga chr17:40264716-40264796 39 3.73e-05 TGAAACTGAG GGGAGGAG CCAGCTGAGC chr12:104995195-10499527 20 3.73e-05 CCTGTCCAGT GGGAGGAG CCTCCTGGGG chr3:122283123-122283203 3 3.73e-05 CA GGGAGGAG GGGGAAGCGG chr8:144629509-144629589 46 5.05e-05 tccaggaaag gggtgggg agttcctgga chr15:45020978-45021058 4 5.05e-05 ATG GGGTGGGG TGAGGGAAGC chr6:100706024-100706104 20 5.05e-05 CAAATGATGA GGGTGGGG AAAAAAAGAG chr22:46589862-46589942 29 5.05e-05 TAATAGGAAG GGGTGGGG ACTTCCCCGG chr2:55921012-55921092 6 6.30e-05 CCGTG GGGCGGAG CCTGATGGAG chr17:80408780-80408860 14 6.30e-05 TCCGGGATCC GGGCGGAG CCGCAGGAGG chr19:10196907-10196987 70 6.30e-05 CGGGGAGGAA GGGCGGAG CCG chr2:231280823-231280903 52 6.30e-05 TTCCCCATTT GGGCGGAG CCCTTTCTGA chr6:126244562-126244642 63 7.65e-05 AGCTCAGAAT GGGAGTGG AATCTGTCCA chr16:31033980-31034060 72 7.65e-05 gtaacatgct gggagtgg c chr3:177332885-177332965 53 8.90e-05 TGACTGAGCG GGGAGAGG TAACTGCAGC chr7:149552532-149552612 57 8.90e-05 gttggtgggt gggagagg tataagaaag chr2:75538120-75538200 16 1.15e-04 GATGTAAGAA GGGTGGAG CGACTTCTTC chr2:163175196-163175276 61 1.15e-04 CTGCCTGGCG GGGAGGGA GTTTCCTCAG chr12:6445453-6445533 73 1.15e-04 TCAGGCCAGA GGGAGGGA chr11:5646130-5646210 47 1.15e-04 CTCCTCAGGA GGGAGGGA CTTCTTCACA chr6:42013470-42013550 60 1.28e-04 AGGGAAACTT GGCAGGGG CCCCAGAACT chr17:41158728-41158808 14 1.28e-04 GGGAAGCCTC GGCAGGGG GCGGCATGTG chr2:216484885-216484965 38 1.67e-04 TACAGTAACA GGGCGTGG CAGGTTGCGC chr21:45275152-45275232 59 1.67e-04 CTTCCCAGGC AGGAGGGG TGTGGTCTGA chr1:154580665-154580745 51 1.67e-04 TTTGGCCAAG AGGAGGGG CTTGAGCAAA chr1:205216560-205216640 54 1.67e-04 TTCCAGGAAT GGGCGTGG CCCTGGGGGT chr3:93692775-93692855 58 1.81e-04 TCGGAGCTGG GGGATGGG CTCTAGTGTT chr12:14437621-14437701 56 1.81e-04 TAGCTTCCTG GGGATGGG AGAGAGGGTT chr1:22118088-22118168 14 1.81e-04 ttccgagaaa gggatggg catttcccag chr20:52516222-52516302 42 2.06e-04 TATAGGAAAC GGGAGAAG GGCAGAGCCA chr9:101614069-101614149 25 2.06e-04 tctgagaaag gggcgagg acttcccaga chr18:23570649-23570729 11 2.06e-04 CTTCCAGGAA GGGCGAGG TATTCAGAGA chr15:67095534-67095614 55 2.31e-04 CCCGGAATCT GGGAGGAA GCATGAGTCA chr5:131831521-131831601 48 2.31e-04 CACCGCCGTT GGGAGGAA AGAGAACTCA chr2:201990476-201990556 28 2.46e-04 GAAACCACCA GGGTGTGG TGGTGAGTAG chr3:171897709-171897789 25 2.46e-04 ctctgatgag gggtgtgg ctgaatgacc chr16:19707814-19707894 2 2.46e-04 T GGGTGTGG TGGAGCTGGG chr19:1132298-1132378 12 2.71e-04 CTTCCTCTAA GGCCGGGG CTGACTTTCA chr2:120989942-120990022 20 3.37e-04 GTTGTCTGCG AGGAGGAG AAACGGCTAA chrX:48794449-48794529 40 3.90e-04 CCTGCGCACA GGCTGGGG GCCCCCTGCT chr6:36315524-36315604 14 3.90e-04 GGCCCAACCT GGAAGGGG CTGTATTTCA -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GGGAGGGG MEME-4 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr11:65188828-65188908 1.2e-05 44_[+4]_28 chr6:15097485-15097565 1.2e-05 72_[+4] chr19:4540157-4540237 1.2e-05 18_[+4]_54 chr15:98619910-98619990 1.2e-05 1_[+4]_71 chr1:159047074-159047154 1.2e-05 9_[+4]_63 chr5:119848599-119848679 1.2e-05 33_[+4]_39 chr1:158979613-158979693 3.7e-05 53_[+4]_19 chr22:18632813-18632893 3.7e-05 45_[+4]_27 chr9:100881488-100881568 3.7e-05 15_[+4]_57 chr6:43597860-43597940 3.7e-05 11_[+4]_61 chr12:12953556-12953636 3.7e-05 64_[+4]_8 chr6:10838826-10838906 3.7e-05 57_[+4]_15 chr8:144105606-144105686 3.7e-05 5_[+4]_67 chr11:4414904-4414984 3.7e-05 60_[+4]_12 chr17:40264716-40264796 3.7e-05 38_[+4]_34 chr12:104995195-10499527 3.7e-05 19_[+4]_53 chr3:122283123-122283203 3.7e-05 2_[+4]_70 chr8:144629509-144629589 5e-05 45_[+4]_27 chr15:45020978-45021058 5e-05 3_[+4]_69 chr6:100706024-100706104 5e-05 19_[+4]_53 chr22:46589862-46589942 5e-05 28_[+4]_44 chr2:55921012-55921092 6.3e-05 5_[+4]_67 chr17:80408780-80408860 6.3e-05 13_[+4]_59 chr19:10196907-10196987 6.3e-05 69_[+4]_3 chr2:231280823-231280903 6.3e-05 51_[+4]_21 chr6:126244562-126244642 7.6e-05 62_[+4]_10 chr16:31033980-31034060 7.6e-05 71_[+4]_1 chr3:177332885-177332965 8.9e-05 52_[+4]_20 chr7:149552532-149552612 8.9e-05 56_[+4]_16 chr2:75538120-75538200 0.00012 15_[+4]_57 chr2:163175196-163175276 0.00012 60_[+4]_12 chr12:6445453-6445533 0.00012 72_[+4] chr11:5646130-5646210 0.00012 46_[+4]_26 chr6:42013470-42013550 0.00013 59_[+4]_13 chr17:41158728-41158808 0.00013 13_[+4]_59 chr2:216484885-216484965 0.00017 37_[+4]_35 chr21:45275152-45275232 0.00017 58_[+4]_14 chr1:154580665-154580745 0.00017 50_[+4]_22 chr1:205216560-205216640 0.00017 53_[+4]_19 chr3:93692775-93692855 0.00018 57_[+4]_15 chr12:14437621-14437701 0.00018 55_[+4]_17 chr1:22118088-22118168 0.00018 13_[+4]_59 chr20:52516222-52516302 0.00021 41_[+4]_31 chr9:101614069-101614149 0.00021 24_[+4]_48 chr18:23570649-23570729 0.00021 10_[+4]_62 chr15:67095534-67095614 0.00023 54_[+4]_18 chr5:131831521-131831601 0.00023 47_[+4]_25 chr2:201990476-201990556 0.00025 27_[+4]_45 chr3:171897709-171897789 0.00025 24_[+4]_48 chr16:19707814-19707894 0.00025 1_[+4]_71 chr19:1132298-1132378 0.00027 11_[+4]_61 chr2:120989942-120990022 0.00034 19_[+4]_53 chrX:48794449-48794529 0.00039 39_[+4]_33 chr6:36315524-36315604 0.00039 13_[+4]_59 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GGGAGGGG MEME-4 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF GGGAGGGG width=8 seqs=54 chr11:65188828-65188908 ( 45) GGGAGGGG 1 chr6:15097485-15097565 ( 73) GGGAGGGG 1 chr19:4540157-4540237 ( 19) GGGAGGGG 1 chr15:98619910-98619990 ( 2) GGGAGGGG 1 chr1:159047074-159047154 ( 10) GGGAGGGG 1 chr5:119848599-119848679 ( 34) GGGAGGGG 1 chr1:158979613-158979693 ( 54) GGGAGGAG 1 chr22:18632813-18632893 ( 46) GGGCGGGG 1 chr9:100881488-100881568 ( 16) GGGCGGGG 1 chr6:43597860-43597940 ( 12) GGGCGGGG 1 chr12:12953556-12953636 ( 65) GGGAGGAG 1 chr6:10838826-10838906 ( 58) GGGCGGGG 1 chr8:144105606-144105686 ( 6) GGGAGGAG 1 chr11:4414904-4414984 ( 61) GGGAGGAG 1 chr17:40264716-40264796 ( 39) GGGAGGAG 1 chr12:104995195-10499527 ( 20) GGGAGGAG 1 chr3:122283123-122283203 ( 3) GGGAGGAG 1 chr8:144629509-144629589 ( 46) GGGTGGGG 1 chr15:45020978-45021058 ( 4) GGGTGGGG 1 chr6:100706024-100706104 ( 20) GGGTGGGG 1 chr22:46589862-46589942 ( 29) GGGTGGGG 1 chr2:55921012-55921092 ( 6) GGGCGGAG 1 chr17:80408780-80408860 ( 14) GGGCGGAG 1 chr19:10196907-10196987 ( 70) GGGCGGAG 1 chr2:231280823-231280903 ( 52) GGGCGGAG 1 chr6:126244562-126244642 ( 63) GGGAGTGG 1 chr16:31033980-31034060 ( 72) GGGAGTGG 1 chr3:177332885-177332965 ( 53) GGGAGAGG 1 chr7:149552532-149552612 ( 57) GGGAGAGG 1 chr2:75538120-75538200 ( 16) GGGTGGAG 1 chr2:163175196-163175276 ( 61) GGGAGGGA 1 chr12:6445453-6445533 ( 73) GGGAGGGA 1 chr11:5646130-5646210 ( 47) GGGAGGGA 1 chr6:42013470-42013550 ( 60) GGCAGGGG 1 chr17:41158728-41158808 ( 14) GGCAGGGG 1 chr2:216484885-216484965 ( 38) GGGCGTGG 1 chr21:45275152-45275232 ( 59) AGGAGGGG 1 chr1:154580665-154580745 ( 51) AGGAGGGG 1 chr1:205216560-205216640 ( 54) GGGCGTGG 1 chr3:93692775-93692855 ( 58) GGGATGGG 1 chr12:14437621-14437701 ( 56) GGGATGGG 1 chr1:22118088-22118168 ( 14) GGGATGGG 1 chr20:52516222-52516302 ( 42) GGGAGAAG 1 chr9:101614069-101614149 ( 25) GGGCGAGG 1 chr18:23570649-23570729 ( 11) GGGCGAGG 1 chr15:67095534-67095614 ( 55) GGGAGGAA 1 chr5:131831521-131831601 ( 48) GGGAGGAA 1 chr2:201990476-201990556 ( 28) GGGTGTGG 1 chr3:171897709-171897789 ( 25) GGGTGTGG 1 chr16:19707814-19707894 ( 2) GGGTGTGG 1 chr19:1132298-1132378 ( 12) GGCCGGGG 1 chr2:120989942-120990022 ( 20) AGGAGGAG 1 chrX:48794449-48794529 ( 40) GGCTGGGG 1 chr6:36315524-36315604 ( 14) GGAAGGGG 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GGGAGGGG MEME-4 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 10.0499 E= 4.8e-013 -215 -1240 196 -1240 -1240 -1240 204 -1240 -373 -174 190 -1240 126 -4 -1240 -66 -1240 -1240 196 -225 -141 -1240 168 -102 26 -1240 154 -1240 -141 -1240 190 -1240 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GGGAGGGG MEME-4 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 54 E= 4.8e-013 0.055556 0.000000 0.944444 0.000000 0.000000 0.000000 1.000000 0.000000 0.018519 0.074074 0.907407 0.000000 0.592593 0.240741 0.000000 0.166667 0.000000 0.000000 0.944444 0.055556 0.092593 0.000000 0.777778 0.129630 0.296296 0.000000 0.703704 0.000000 0.092593 0.000000 0.907407 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GGGAGGGG MEME-4 regular expression -------------------------------------------------------------------------------- GGG[AC]GG[GA]G -------------------------------------------------------------------------------- Time 14.71 secs. ******************************************************************************** ******************************************************************************** MOTIF YYYTCCCC MEME-5 width = 8 sites = 55 llr = 425 E-value = 1.5e-007 ******************************************************************************** -------------------------------------------------------------------------------- Motif YYYTCCCC MEME-5 Description -------------------------------------------------------------------------------- Simplified A 2::::::2 pos.-specific C 473:aaa6 probability G :::::::: matrix T 437a:::1 bits 2.0 *** 1.8 **** 1.6 **** 1.4 **** Relative 1.2 **** Entropy 1.0 ****** (11.1 bits) 0.8 ******* 0.6 ******* 0.4 ******** 0.2 ******** 0.0 -------- Multilevel TCTTCCCC consensus CTC A sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YYYTCCCC MEME-5 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr9:90289670-90289750 19 1.69e-05 CCGTGAATGG TCTTCCCC ATCAGCTTGC chr19:50880910-50880990 7 1.69e-05 TGACTC TCTTCCCC ACCCAGCCCT chr1:173640228-173640308 17 3.27e-05 catcttgtct ccttcccc actttaagtt chr15:45020978-45021058 30 3.27e-05 GCAACCCTGC CCTTCCCC TTTCTCGGAA chr15:57029724-57029804 27 3.27e-05 cctttctgct ccttcccc ttctaagaag chr20:35579209-35579289 36 3.27e-05 caagccagtt ccttcccc ttcaggaaaa chr1:154580665-154580745 24 3.27e-05 CCTCGGAAAG CCTTCCCC TCCGGAAAGT chr6:10838826-10838906 49 3.27e-05 GCAGGCCCCG CCTTCCCC GGGGCGGGGC chr3:5191305-5191385 4 3.27e-05 tcc ccttcccc acttaagttt chr10:91087612-91087692 42 3.27e-05 GTTTCCTCTT CCTTCCCC TAAAAGCAAT chr8:144629509-144629589 72 4.86e-05 gaacggattg tcctcccc c chr1:22118088-22118168 42 4.86e-05 aactgagagt tcctcccc tttttagacc chr1:9834940-9835020 50 4.86e-05 aactgaggac tcctcccc attttagagc chr3:48514483-48514563 22 4.86e-05 AGTTTCAATT TCCTCCCC TTTTGGAGAA chr17:57863954-57864034 42 8.15e-05 TGAAAATTCC CCCTCCCC TTCATTTCCA chr1:155163169-155163249 17 8.15e-05 GTTTTGGGCT CCCTCCCC CCACCACTTC chr7:120640183-120640263 26 8.15e-05 TTTGGTTTCG TTTTCCCC CTTGGCTTCC chr3:172312543-172312623 63 8.15e-05 TTCCGACCTT CCCTCCCC GCCAAGGCAA chrX:154014325-154014405 12 8.15e-05 GCATGGTTAA CCCTCCCC CACCCATTAT chr2:37384094-37384174 31 8.15e-05 CTCAGTTTCG TTTTCCCC TTGGACTCCG chr1:27998785-27998865 29 8.15e-05 TGCAGTTTCA TTTTCCCC TCTCTCCCAG chr2:231280823-231280903 40 8.15e-05 TTCACTTCTC TTTTCCCC ATTTGGGCGG chr13:43566399-43566479 64 1.14e-04 GCCCCAGAGA ACTTCCCC ACGTATTCT chr9:108641637-108641717 22 1.14e-04 tctctgtttc acttcccc actcccctcc chr13:50070001-50070081 15 1.14e-04 GCACACCCAA CTTTCCCC GGGCCGGCTA chr22:46589862-46589942 37 1.14e-04 AGGGGTGGGG ACTTCCCC GGGATATTCT chr1:150534650-150534730 36 1.14e-04 GGCTCAGCTG ACTTCCCC GAAGCTCCCC chr1:169337688-169337768 36 1.14e-04 TTAGGTTTCG ACTTCCCC GGACAGCAAA chr10:91092176-91092256 69 1.14e-04 TTTCACTTTC CTTTCCCC TTTC chr21:45275152-45275232 48 1.47e-04 CTGTGTGGTG CCTTCCCA GGCAGGAGGG chr8:103818634-103818714 57 1.64e-04 TCGCCCTCTC TTCTCCCC CATCCCCCGT chr14:100841767-10084184 3 1.64e-04 CG TTCTCCCC ACCCTGCATT chr2:120989942-120990022 58 1.64e-04 CTGGGGTGCT TTCTCCCC ACCTATCAGC chr8:90996283-90996363 43 2.27e-04 CGTGGTAGTC ATTTCCCC AAACTGTCCA chr15:98619910-98619990 61 2.27e-04 TGTTGTCCAT TCCTCCCA AACCTCCACC chr15:75417763-75417843 1 2.27e-04 . tcctccca cttcggcttc chr9:71584588-71584668 23 2.27e-04 CCTGAGCACA TCCTCCCA CCCGAGGCCC chr1:205216560-205216640 1 2.27e-04 . ATTTCCCC TTCAGTTGCA chr17:60711460-60711540 60 2.78e-04 actgagggag tcttccct ttttagaccc chr12:6445453-6445533 36 2.78e-04 AAGGGAAATC TTTTCCCA GCAACTCCGC chr10:25156323-25156403 2 2.78e-04 T TCTTCCCT CTTGTCAGTT chr9:33081350-33081430 63 2.78e-04 TAAATGGGCC CCCTCCCA TAAGTCCATG chr15:81400313-81400393 2 2.78e-04 G TTTTCCCA TACTAtctct chr4:89300514-89300594 26 2.78e-04 CTCAGTTTCG TTTTCCCA ACGCCCCTCG chr10:3975328-3975408 50 3.28e-04 TTTCTGTTTC CTTTCCCA AGATGTACTA chr1:11851017-11851097 67 3.28e-04 TGCCAGTATC ACTTCCCA CCCCTG chr16:11406643-11406723 60 3.28e-04 GAAAGGCTGT CCTTCCCT ACTCCAAGCC chr12:113344699-11334477 37 3.78e-04 CAAAGACAGC TCCTCCCT TCTGAGGAAA chr2:99176946-99177026 26 4.43e-04 ACACCTCATA CTCTCCCA GTTTGCTTTC chrX:40869487-40869567 56 4.43e-04 tcctagaagc ccctccct gctgtgtttc chr6:99281972-99282052 19 4.43e-04 GCGACCCAGC TTTTCCCT TACCCCCTCC chr14:24630360-24630440 64 4.43e-04 TGGGAAAAGG CCCTCCCT GGAGGAGAA chr11:117043904-11704398 40 4.95e-04 TATCACAGAT ATTTCCCA GTGTGAATGG chr12:113376105-11337618 48 4.95e-04 AAAGCAGGGA ATTTCCCA AGTTTGGGGA chr4:185395890-185395970 72 5.96e-04 TTTCATTTTC GCTTCCCC A -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YYYTCCCC MEME-5 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr9:90289670-90289750 1.7e-05 18_[+5]_54 chr19:50880910-50880990 1.7e-05 6_[+5]_66 chr1:173640228-173640308 3.3e-05 16_[+5]_56 chr15:45020978-45021058 3.3e-05 29_[+5]_43 chr15:57029724-57029804 3.3e-05 26_[+5]_46 chr20:35579209-35579289 3.3e-05 35_[+5]_37 chr1:154580665-154580745 3.3e-05 23_[+5]_49 chr6:10838826-10838906 3.3e-05 48_[+5]_24 chr3:5191305-5191385 3.3e-05 3_[+5]_69 chr10:91087612-91087692 3.3e-05 41_[+5]_31 chr8:144629509-144629589 4.9e-05 71_[+5]_1 chr1:22118088-22118168 4.9e-05 41_[+5]_31 chr1:9834940-9835020 4.9e-05 49_[+5]_23 chr3:48514483-48514563 4.9e-05 21_[+5]_51 chr17:57863954-57864034 8.1e-05 41_[+5]_31 chr1:155163169-155163249 8.1e-05 16_[+5]_56 chr7:120640183-120640263 8.1e-05 25_[+5]_47 chr3:172312543-172312623 8.1e-05 62_[+5]_10 chrX:154014325-154014405 8.1e-05 11_[+5]_61 chr2:37384094-37384174 8.1e-05 30_[+5]_42 chr1:27998785-27998865 8.1e-05 28_[+5]_44 chr2:231280823-231280903 8.1e-05 39_[+5]_33 chr13:43566399-43566479 0.00011 63_[+5]_9 chr9:108641637-108641717 0.00011 21_[+5]_51 chr13:50070001-50070081 0.00011 14_[+5]_58 chr22:46589862-46589942 0.00011 36_[+5]_36 chr1:150534650-150534730 0.00011 35_[+5]_37 chr1:169337688-169337768 0.00011 35_[+5]_37 chr10:91092176-91092256 0.00011 68_[+5]_4 chr21:45275152-45275232 0.00015 47_[+5]_25 chr8:103818634-103818714 0.00016 56_[+5]_16 chr14:100841767-10084184 0.00016 2_[+5]_70 chr2:120989942-120990022 0.00016 57_[+5]_15 chr8:90996283-90996363 0.00023 42_[+5]_30 chr15:98619910-98619990 0.00023 60_[+5]_12 chr15:75417763-75417843 0.00023 [+5]_72 chr9:71584588-71584668 0.00023 22_[+5]_50 chr1:205216560-205216640 0.00023 [+5]_72 chr17:60711460-60711540 0.00028 59_[+5]_13 chr12:6445453-6445533 0.00028 35_[+5]_37 chr10:25156323-25156403 0.00028 1_[+5]_71 chr9:33081350-33081430 0.00028 62_[+5]_10 chr15:81400313-81400393 0.00028 1_[+5]_71 chr4:89300514-89300594 0.00028 25_[+5]_47 chr10:3975328-3975408 0.00033 49_[+5]_23 chr1:11851017-11851097 0.00033 66_[+5]_6 chr16:11406643-11406723 0.00033 59_[+5]_13 chr12:113344699-11334477 0.00038 36_[+5]_36 chr2:99176946-99177026 0.00044 25_[+5]_47 chrX:40869487-40869567 0.00044 55_[+5]_17 chr6:99281972-99282052 0.00044 18_[+5]_54 chr14:24630360-24630440 0.00044 63_[+5]_9 chr11:117043904-11704398 0.0005 39_[+5]_33 chr12:113376105-11337618 0.0005 47_[+5]_25 chr4:185395890-185395970 0.0006 71_[+5]_1 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YYYTCCCC MEME-5 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF YYYTCCCC width=8 seqs=55 chr9:90289670-90289750 ( 19) TCTTCCCC 1 chr19:50880910-50880990 ( 7) TCTTCCCC 1 chr1:173640228-173640308 ( 17) CCTTCCCC 1 chr15:45020978-45021058 ( 30) CCTTCCCC 1 chr15:57029724-57029804 ( 27) CCTTCCCC 1 chr20:35579209-35579289 ( 36) CCTTCCCC 1 chr1:154580665-154580745 ( 24) CCTTCCCC 1 chr6:10838826-10838906 ( 49) CCTTCCCC 1 chr3:5191305-5191385 ( 4) CCTTCCCC 1 chr10:91087612-91087692 ( 42) CCTTCCCC 1 chr8:144629509-144629589 ( 72) TCCTCCCC 1 chr1:22118088-22118168 ( 42) TCCTCCCC 1 chr1:9834940-9835020 ( 50) TCCTCCCC 1 chr3:48514483-48514563 ( 22) TCCTCCCC 1 chr17:57863954-57864034 ( 42) CCCTCCCC 1 chr1:155163169-155163249 ( 17) CCCTCCCC 1 chr7:120640183-120640263 ( 26) TTTTCCCC 1 chr3:172312543-172312623 ( 63) CCCTCCCC 1 chrX:154014325-154014405 ( 12) CCCTCCCC 1 chr2:37384094-37384174 ( 31) TTTTCCCC 1 chr1:27998785-27998865 ( 29) TTTTCCCC 1 chr2:231280823-231280903 ( 40) TTTTCCCC 1 chr13:43566399-43566479 ( 64) ACTTCCCC 1 chr9:108641637-108641717 ( 22) ACTTCCCC 1 chr13:50070001-50070081 ( 15) CTTTCCCC 1 chr22:46589862-46589942 ( 37) ACTTCCCC 1 chr1:150534650-150534730 ( 36) ACTTCCCC 1 chr1:169337688-169337768 ( 36) ACTTCCCC 1 chr10:91092176-91092256 ( 69) CTTTCCCC 1 chr21:45275152-45275232 ( 48) CCTTCCCA 1 chr8:103818634-103818714 ( 57) TTCTCCCC 1 chr14:100841767-10084184 ( 3) TTCTCCCC 1 chr2:120989942-120990022 ( 58) TTCTCCCC 1 chr8:90996283-90996363 ( 43) ATTTCCCC 1 chr15:98619910-98619990 ( 61) TCCTCCCA 1 chr15:75417763-75417843 ( 1) TCCTCCCA 1 chr9:71584588-71584668 ( 23) TCCTCCCA 1 chr1:205216560-205216640 ( 1) ATTTCCCC 1 chr17:60711460-60711540 ( 60) TCTTCCCT 1 chr12:6445453-6445533 ( 36) TTTTCCCA 1 chr10:25156323-25156403 ( 2) TCTTCCCT 1 chr9:33081350-33081430 ( 63) CCCTCCCA 1 chr15:81400313-81400393 ( 2) TTTTCCCA 1 chr4:89300514-89300594 ( 26) TTTTCCCA 1 chr10:3975328-3975408 ( 50) CTTTCCCA 1 chr1:11851017-11851097 ( 67) ACTTCCCA 1 chr16:11406643-11406723 ( 60) CCTTCCCT 1 chr12:113344699-11334477 ( 37) TCCTCCCT 1 chr2:99176946-99177026 ( 26) CTCTCCCA 1 chrX:40869487-40869567 ( 56) CCCTCCCT 1 chr6:99281972-99282052 ( 19) TTTTCCCT 1 chr14:24630360-24630440 ( 64) CCCTCCCT 1 chr11:117043904-11704398 ( 40) ATTTCCCA 1 chr12:113376105-11337618 ( 48) ATTTCCCA 1 chr4:185395890-185395970 ( 72) GCTTCCCC 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YYYTCCCC MEME-5 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 10.0332 E= 1.5e-007 -44 63 -373 67 -1243 140 -1243 39 -1243 48 -1243 131 -1243 -1243 -1243 192 -1243 202 -1243 -1243 -1243 202 -1243 -1243 -1243 202 -1243 -1243 -6 136 -1243 -105 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YYYTCCCC MEME-5 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 55 E= 1.5e-007 0.181818 0.381818 0.018182 0.418182 0.000000 0.654545 0.000000 0.345455 0.000000 0.345455 0.000000 0.654545 0.000000 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.236364 0.636364 0.000000 0.127273 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YYYTCCCC MEME-5 regular expression -------------------------------------------------------------------------------- [TC][CT][TC]TCCC[CA] -------------------------------------------------------------------------------- Time 17.80 secs. ******************************************************************************** ******************************************************************************** SUMMARY OF MOTIFS ******************************************************************************** -------------------------------------------------------------------------------- Combined block diagrams: non-overlapping sites with p-value < 0.0001 -------------------------------------------------------------------------------- SEQUENCE NAME COMBINED P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr20:36751436-36751516 7.56e-03 43_[+1(7.26e-05)]_29 chr14:94576944-94577024 4.33e-05 44_[+3(4.16e-05)]_28 chr18:43554213-43554293 1.04e-01 63_[+1(8.70e-05)]_9 chr16:50699395-50699475 4.39e-01 80 chr8:29957325-29957405 8.61e-03 42_[+1(4.28e-05)]_30 chr11:57333727-57333807 1.44e-02 64_[+3(4.16e-05)]_8 chr15:92015887-92015967 3.88e-02 80 chr3:122283123-122283203 5.96e-04 2_[+4(3.73e-05)]_41_[+3(2.70e-05)]_\ 21 chr4:89300514-89300594 1.94e-04 16_[+2(1.78e-05)]_48_[+3(2.70e-05)] chr10:25026137-25026217 1.83e-02 80 chr1:185303423-185303503 7.14e-02 80 chr5:131832712-131832792 3.10e-03 50_[+1(2.84e-05)]_22 chr2:97151892-97151972 6.57e-03 63_[+3(2.70e-05)]_9 chr10:91174282-91174362 1.11e-01 19_[+2(3.68e-05)]_13_[+2(1.78e-05)]_\ 32 chr11:5646130-5646210 3.53e-03 12_[+2(7.27e-05)]_60 chr12:104995195-10499527 5.90e-03 19_[+4(3.73e-05)]_53 chr18:60173635-60173715 1.75e-02 22_[+2(1.78e-05)]_33_[+2(9.17e-05)]_\ 9 chr3:122399598-122399678 1.01e-04 54_[+3(1.36e-05)]_18 chr1:39251924-39252004 3.84e-03 26_[+1(4.28e-05)]_46 chr15:81400313-81400393 2.84e-04 24_[+2(5.46e-05)]_48 chr12:121477036-12147711 2.19e-02 17_[+2(1.78e-05)]_55 chr16:19707814-19707894 6.98e-03 42_[+1(5.81e-05)]_30 chr11:615632-615712 1.35e-02 63_[+3(2.70e-05)]_9 chr10:91087612-91087692 4.63e-04 15_[+2(3.68e-05)]_18_[+5(3.27e-05)]_\ 31 chr10:91152276-91152356 1.06e-01 80 chr17:40264716-40264796 6.77e-03 25_[+3(8.41e-05)]_5_[+4(3.73e-05)]_\ 34 chr12:113344699-11334477 3.29e-03 51_[+3(1.36e-05)]_21 chr21:42792447-42792527 9.83e-05 44_[+3(4.16e-05)]_14_[+1(2.84e-05)]_\ 6 chr11:4414904-4414984 1.89e-04 3_[+2(1.78e-05)]_31_[+4(3.73e-05)]_\ 10_[+4(3.73e-05)]_3_[+4(3.73e-05)]_1 chr4:38285521-38285601 3.12e-02 32_[+3(8.41e-05)]_40 chr8:144105606-144105686 3.76e-03 5_[+4(3.73e-05)]_38_[+4(8.90e-05)]_\ 21 chr1:205216560-205216640 3.15e-04 44_[+1(4.28e-05)]_28 chr7:92776946-92777026 6.10e-02 21_[+2(3.68e-05)]_51 chr3:130791858-130791938 2.62e-02 32_[+1(4.28e-05)]_40 chr2:231084689-231084769 5.16e-03 40_[+1(8.70e-05)]_5_[+3(6.96e-05)]_\ 19 chr7:92747397-92747477 3.38e-03 23_[+2(1.78e-05)]_49 chr21:38791958-38792038 2.29e-02 80 chr2:201248606-201248686 1.86e-03 50_[+3(1.36e-05)]_22 chr12:102330151-10233023 4.36e-01 80 chr2:120989942-120990022 2.13e-04 80 chr12:113376105-11337618 1.37e-03 26_[+3(1.36e-05)]_46 chr6:47382628-47382708 2.07e-02 80 chr2:231280823-231280903 3.85e-04 39_[+5(8.15e-05)]_4_[+4(6.30e-05)]_\ 21 chr15:74287061-74287141 2.65e-02 80 chr10:91092176-91092256 4.47e-03 17_[+2(1.78e-05)]_29_[+2(1.78e-05)]_\ 18 chr2:231200768-231200848 7.84e-03 39_[+1(7.26e-05)]_33 chr17:77061361-77061441 6.31e-02 80 chr9:33081350-33081430 2.31e-02 80 chr3:5191305-5191385 1.15e-03 3_[+5(3.27e-05)]_69 chr18:2641788-2641868 3.29e-02 37_[+2(1.78e-05)]_35 chr9:32526255-32526335 1.98e-03 80 chr6:16237011-16237091 1.57e-03 80 chr4:17578595-17578675 4.61e-03 38_[+2(1.78e-05)]_34 chr2:146481653-146481733 3.46e-02 36_[+1(4.28e-05)]_36 chr9:71584588-71584668 4.24e-03 41_[+1(2.84e-05)]_31 chr1:25682520-25682600 7.14e-03 36_[+1(5.81e-05)]_17_[+2(9.17e-05)]_\ 11 chr8:144107938-144108018 1.34e-02 19_[+2(1.78e-05)]_53 chr1:169337688-169337768 1.24e-02 80 chr1:27998785-27998865 3.61e-02 28_[+5(8.15e-05)]_33_[+5(8.15e-05)]_\ 3 chr4:169239939-169240019 2.89e-04 44_[+2(1.78e-05)]_28 chr11:117043904-11704398 8.18e-02 80 chr7:87834657-87834737 4.62e-03 53_[+3(8.41e-05)]_19 chr2:74433412-74433492 3.51e-02 80 chr1:150534650-150534730 1.42e-01 80 chr2:7017754-7017834 8.58e-04 10_[+2(1.78e-05)]_62 chr3:48514483-48514563 4.30e-05 9_[+2(1.78e-05)]_4_[+5(4.86e-05)]_\ 51 chr22:46589862-46589942 3.20e-03 28_[+4(5.05e-05)]_44 chr5:84943801-84943881 1.29e-01 80 chr7:149552532-149552612 2.38e-02 56_[+4(8.90e-05)]_16 chr14:24630360-24630440 1.99e-02 80 chr6:10838826-10838906 4.00e-03 48_[+5(3.27e-05)]_1_[+4(3.73e-05)]_\ 15 chr2:152146439-152146519 1.92e-02 6_[+2(7.27e-05)]_66 chr11:313965-314045 1.31e-02 70_[+3(8.41e-05)]_2 chr14:97297399-97297479 4.57e-02 80 chr1:154580665-154580745 1.02e-04 23_[+5(3.27e-05)]_49 chr6:42158721-42158801 1.28e-01 80 chr4:73419390-73419470 1.79e-02 36_[+1(5.81e-05)]_36 chr16:11406643-11406723 1.01e-03 38_[+2(1.78e-05)]_34 chr6:100706024-100706104 2.54e-04 19_[+4(5.05e-05)]_12_[+3(1.36e-05)]_\ 33 chr4:169401688-169401768 2.87e-01 80 chr6:36315524-36315604 7.94e-02 80 chr6:168241706-168241786 2.96e-02 31_[+3(4.16e-05)]_41 chr2:37384094-37384174 2.83e-03 21_[+2(1.78e-05)]_1_[+5(8.15e-05)]_\ 42 chr20:35579209-35579289 2.70e-05 35_[+5(3.27e-05)]_28_[+3(6.96e-05)]_\ 1 chr3:172230374-172230454 2.74e-03 80 chr22:50978142-50978222 3.28e-02 80 chr3:171897709-171897789 1.08e-01 80 chr15:81615195-81615275 9.54e-02 72_[+1(4.28e-05)] chr19:17516531-17516611 4.64e-05 24_[+2(1.78e-05)]_4_[+1(7.26e-05)]_\ 36 chr15:101137152-10113723 2.45e-02 43_[+1(5.81e-05)]_29 chr7:36444533-36444613 1.40e-02 69_[+3(6.96e-05)]_3 chr5:131826556-131826636 6.29e-01 80 chrX:154014325-154014405 3.55e-03 11_[+5(8.15e-05)]_61 chr5:81763178-81763258 2.58e-02 24_[+3(8.41e-05)]_48 chr21:35029618-35029698 1.07e-02 7_[+2(1.78e-05)]_3_[+2(3.68e-05)]_\ 54 chr13:111527204-11152728 1.62e-02 29_[+1(2.84e-05)]_43 chr5:119848599-119848679 3.66e-03 33_[+4(1.24e-05)]_39 chr3:177332885-177332965 1.78e-03 52_[+4(8.90e-05)]_20 chr15:57029724-57029804 1.55e-03 26_[+5(3.27e-05)]_46 chr7:134832719-134832799 7.44e-02 47_[+3(1.36e-05)]_25 chr2:26716571-26716651 1.52e-01 80 chr10:25156323-25156403 1.39e-02 13_[+2(1.78e-05)]_59 chr17:41158728-41158808 1.01e-03 57_[+3(4.16e-05)]_15 chr7:4660204-4660284 1.31e-03 35_[+1(5.81e-05)]_37 chr11:64764505-64764585 3.06e-02 4_[+2(1.78e-05)]_68 chr2:7005885-7005965 9.43e-02 13_[+3(1.36e-05)]_26_[+3(1.36e-05)]_\ 16_[+3(1.36e-05)]_1 chr15:75417763-75417843 5.41e-03 80 chr6:138043957-138044037 4.49e-02 80 chr19:8799353-8799433 3.24e-02 71_[+1(5.81e-05)]_1 chr2:202084933-202085013 8.93e-03 80 chr3:172312543-172312623 4.40e-03 62_[+5(8.15e-05)]_10 chr15:52024148-52024228 2.69e-02 42_[+2(1.78e-05)]_30 chr1:11851017-11851097 1.25e-03 33_[+1(1.43e-05)]_39 chr3:146262417-146262497 6.89e-02 80 chr7:100145711-100145791 1.19e-02 45_[+1(7.26e-05)]_27 chr1:8812665-8812745 4.78e-02 80 chr17:26595403-26595483 3.99e-02 58_[+3(1.36e-05)]_14 chr12:6445453-6445533 1.25e-05 18_[+1(2.84e-05)]_54 chr6:42013470-42013550 1.45e-03 80 chr6:32821581-32821661 8.63e-02 20_[+3(2.70e-05)]_52 chr2:38701190-38701270 1.54e-01 80 chr10:52304834-52304914 2.07e-02 31_[+1(1.43e-05)]_41 chr19:50880910-50880990 2.70e-02 6_[+5(1.69e-05)]_66 chr2:163175196-163175276 3.81e-04 11_[+2(9.17e-05)]_61 chr2:28753816-28753896 4.98e-02 17_[+1(7.26e-05)]_55 chr6:99281972-99282052 1.55e-04 33_[+2(5.46e-05)]_22_[+3(1.36e-05)]_\ 9 chr5:39077199-39077279 5.71e-02 80 chr1:159047074-159047154 1.75e-04 9_[+4(1.24e-05)]_24_[+1(1.43e-05)]_\ 31 chr14:74229269-74229349 1.32e-02 37_[+1(2.84e-05)]_35 chr13:50070001-50070081 1.26e-03 62_[+3(1.36e-05)]_10 chr1:152007201-152007281 6.46e-02 80 chr11:5710949-5711029 3.14e-02 80 chr7:120640183-120640263 2.13e-03 25_[+5(8.15e-05)]_47 chr19:47760201-47760281 2.12e-01 80 chr22:36044411-36044491 2.72e-04 25_[+1(5.81e-05)]_38_[+3(6.96e-05)]_\ 1 chr1:54842892-54842972 7.04e-04 15_[+3(8.41e-05)]_57 chrX:48794449-48794529 1.79e-02 80 chr1:110453391-110453471 6.93e-02 80 chr9:108641637-108641717 2.42e-04 13_[+2(9.17e-05)]_25_[+1(5.81e-05)]_\ 26 chr5:131680638-131680718 3.72e-02 14_[+1(2.84e-05)]_58 chr7:92634374-92634454 1.32e-01 80 chr2:9904341-9904421 3.99e-01 80 chr2:240202051-240202131 8.53e-02 80 chr10:80719153-80719233 1.47e-01 62_[+3(6.96e-05)]_10 chr3:36949602-36949682 5.32e-02 22_[+2(7.27e-05)]_50 chr1:155163169-155163249 2.95e-03 16_[+5(8.15e-05)]_8_[+1(1.43e-05)]_\ 40 chr1:948708-948788 1.51e-03 63_[+3(6.96e-05)]_9 chr19:48018762-48018842 3.86e-02 80 chr19:893299-893379 4.39e-01 80 chr12:32174020-32174100 9.93e-03 62_[+1(7.26e-05)]_10 chr12:12953556-12953636 8.25e-02 64_[+4(3.73e-05)]_8 chr10:114851848-11485192 6.26e-03 16_[+3(4.16e-05)]_56 chr16:11391451-11391531 3.42e-02 80 chr13:43566399-43566479 1.65e-03 80 chr5:43040458-43040538 1.22e-02 21_[+1(2.84e-05)]_51 chr2:152118323-152118403 9.45e-02 80 chr15:45020978-45021058 2.60e-06 3_[+4(5.05e-05)]_18_[+5(3.27e-05)]_\ 43 chr14:97284354-97284434 1.16e-02 8_[+2(7.27e-05)]_64 chr16:31033980-31034060 4.12e-05 13_[+1(5.81e-05)]_50_[+4(7.65e-05)]_\ 1 chrX:41190885-41190965 2.91e-02 68_[+3(1.36e-05)]_4 chr14:100841767-10084184 4.18e-02 80 chr6:30457084-30457164 7.71e-02 80 chrX:40869487-40869567 2.43e-03 80 chr8:20060062-20060142 1.84e-02 27_[+1(4.28e-05)]_45 chr20:62205543-62205623 2.35e-02 35_[+2(1.78e-05)]_37 chr5:10627856-10627936 2.84e-03 80 chr2:99176946-99177026 5.72e-02 80 chr8:26150630-26150710 8.96e-03 80 chr8:10488036-10488116 1.42e-03 20_[+2(7.27e-05)]_4_[+2(9.17e-05)]_\ 40 chr19:51727739-51727819 1.99e-02 80 chr7:74064475-74064555 7.85e-02 28_[+3(8.41e-05)]_7_[+3(2.70e-05)]_\ 29 chr1:173640228-173640308 1.41e-02 16_[+5(3.27e-05)]_56 chr12:56754195-56754275 4.27e-03 56_[+3(6.96e-05)]_16 chr11:78356415-78356495 4.95e-01 80 chr8:103818634-103818714 8.20e-02 80 chr1:113480991-113481071 5.73e-04 27_[+2(7.27e-05)]_45 chr1:6464831-6464911 1.08e-01 80 chr5:142604444-142604524 3.39e-03 38_[+1(2.84e-05)]_34 chr19:10196907-10196987 1.53e-03 8_[+4(6.30e-05)]_28_[+3(2.70e-05)]_\ 17_[+4(6.30e-05)]_3 chr1:44514057-44514137 6.15e-02 80 chr17:60711460-60711540 8.99e-04 42_[+1(1.43e-05)]_30 chr7:105924488-105924568 6.63e-03 80 chr16:17922035-17922115 1.28e-02 27_[+3(4.16e-05)]_45 chr6:43597860-43597940 2.26e-03 11_[+4(3.73e-05)]_61 chr15:43398349-43398429 1.79e-04 19_[+1(1.43e-05)]_36_[+5(8.15e-05)]_\ 9 chr8:8864277-8864357 1.15e-02 80 chr9:96725353-96725433 6.81e-02 6_[+1(4.28e-05)]_66 chr9:100881488-100881568 2.96e-03 15_[+4(3.73e-05)]_11_[+3(6.96e-05)]_\ 10_[+4(3.73e-05)]_20 chr17:80408780-80408860 7.35e-03 13_[+4(6.30e-05)]_59 chr1:21670071-21670151 9.18e-02 52_[+3(8.41e-05)]_20 chr21:45275152-45275232 3.07e-04 80 chr10:3975328-3975408 1.04e-03 41_[+2(9.17e-05)]_31 chr18:23570649-23570729 1.09e-04 2_[+1(4.28e-05)]_33_[+1(1.43e-05)]_\ 29 chr16:3313886-3313966 7.55e-04 20_[+2(1.78e-05)]_52 chr5:131831521-131831601 2.75e-02 80 chr12:50665870-50665950 8.54e-04 3_[+2(3.68e-05)]_13_[+1(4.28e-05)]_\ 48 chr22:18632813-18632893 4.91e-05 34_[+3(1.36e-05)]_3_[+4(3.73e-05)]_\ 27 chr1:9834940-9835020 3.23e-04 11_[+1(1.43e-05)]_13_[+1(1.43e-05)]_\ 9_[+5(4.86e-05)]_23 chr7:2445739-2445819 8.43e-02 65_[+2(3.68e-05)]_7 chr15:67095534-67095614 3.03e-04 43_[+1(1.43e-05)]_29 chr1:22118088-22118168 2.85e-06 4_[+1(8.70e-05)]_13_[+1(7.26e-05)]_\ 8_[+5(4.86e-05)]_31 chr7:116688668-116688748 4.84e-02 80 chr2:216696251-216696331 1.82e-02 60_[+3(6.96e-05)]_12 chr12:117463514-11746359 6.96e-03 53_[+1(1.43e-05)]_19 chr15:98619910-98619990 1.44e-03 1_[+4(1.24e-05)]_71 chr7:138794062-138794142 5.52e-01 80 chr10:3871190-3871270 4.35e-03 46_[+3(8.41e-05)]_26 chr7:138794522-138794602 5.42e-02 40_[+1(1.43e-05)]_32 chr2:216484885-216484965 1.99e-01 80 chr3:52115064-52115144 2.37e-02 30_[+1(5.81e-05)]_42 chr19:10381709-10381789 1.73e-02 12_[+1(2.84e-05)]_60 chr4:185395890-185395970 4.41e-03 80 chr12:14437621-14437701 4.75e-02 80 chr2:178107363-178107443 2.18e-01 80 chr17:30454490-30454570 1.09e-01 26_[+2(1.78e-05)]_46 chr8:144629509-144629589 2.98e-05 35_[+1(4.28e-05)]_2_[+4(5.05e-05)]_\ 3_[+1(5.81e-05)]_7_[+5(4.86e-05)]_1 chr6:126244562-126244642 2.75e-03 62_[+4(7.65e-05)]_10 chr6:53178699-53178779 2.57e-03 61_[+1(7.26e-05)]_11 chrX:138295709-138295789 3.35e-01 80 chr6:119634242-119634322 2.55e-02 80 chr9:90289670-90289750 1.65e-03 18_[+5(1.69e-05)]_38_[+3(6.96e-05)]_\ 8 chr12:49484208-49484288 3.06e-02 18_[+1(1.43e-05)]_54 chr19:4540157-4540237 1.36e-03 18_[+4(1.24e-05)]_19_[+1(5.81e-05)]_\ 27 chr2:201990476-201990556 1.26e-02 80 chr17:57863954-57864034 3.28e-03 41_[+5(8.15e-05)]_31 chr19:1132298-1132378 8.37e-03 80 chr16:48642597-48642677 2.42e-04 47_[+2(1.78e-05)]_25 chr9:101614069-101614149 3.32e-04 35_[+1(7.26e-05)]_37 chr2:191878973-191879053 6.11e-01 80 chr4:170548186-170548266 2.53e-01 80 chr17:27505523-27505603 4.96e-01 80 chr20:388956-389036 5.63e-03 42_[+4(3.73e-05)]_30 chr3:93692775-93692855 4.51e-03 34_[+1(4.28e-05)]_38 chr2:169856326-169856406 5.15e-01 80 chr2:55921012-55921092 1.64e-04 5_[+4(6.30e-05)]_67 chr5:142965767-142965847 2.37e-01 19_[+1(5.81e-05)]_53 chr6:15097485-15097565 4.08e-04 17_[+1(5.81e-05)]_47_[+4(1.24e-05)] chr4:78656214-78656294 3.13e-02 80 chr12:127568046-12756812 7.67e-01 80 chr20:52516222-52516302 6.56e-02 80 chr2:75538120-75538200 1.76e-03 66_[+3(1.36e-05)]_6 chr1:180554731-180554811 9.89e-03 29_[+1(4.28e-05)]_43 chr2:20776597-20776677 1.55e-02 3_[+2(9.17e-05)]_69 chr5:149957855-149957935 1.86e-02 80 chr2:86811361-86811441 1.42e-01 3_[+2(3.68e-05)]_69 chr1:158979613-158979693 1.96e-05 30_[+3(1.36e-05)]_15_[+4(3.73e-05)]_\ 19 chr11:65188828-65188908 2.01e-03 31_[+1(8.70e-05)]_5_[+4(1.24e-05)]_\ 28 chrX:154564131-154564211 9.15e-02 80 chr20:60982761-60982841 1.93e-02 2_[+1(1.43e-05)]_70 chr8:90996283-90996363 6.61e-03 13_[+3(8.41e-05)]_59 -------------------------------------------------------------------------------- ******************************************************************************** ******************************************************************************** Stopped because requested number of motifs (5) found. ******************************************************************************** CPU: c17n09.farnam.hpc.yale.internal ********************************************************************************