******************************************************************************** MEME - Motif discovery tool ******************************************************************************** MEME version 5.3.3 (Release date: Sun Feb 7 15:39:52 2021 -0800) For further information on how to interpret these results please access https://meme-suite.org/meme. To get a copy of the MEME Suite software please access https://meme-suite.org. ******************************************************************************** ******************************************************************************** REFERENCE ******************************************************************************** If you use this program in your research, please cite: Timothy L. Bailey and Charles Elkan, "Fitting a mixture model by expectation maximization to discover motifs in biopolymers", Proceedings of the Second International Conference on Intelligent Systems for Molecular Biology, pp. 28-36, AAAI Press, Menlo Park, California, 1994. ******************************************************************************** ******************************************************************************** TRAINING SET ******************************************************************************** PRIMARY SEQUENCES= ../result/final_prediction/K562/fasta/RankLinear0.6_40/SREBF1.fasta CONTROL SEQUENCES= --none-- ALPHABET= ACGT Sequence name Weight Length Sequence name Weight Length ------------- ------ ------ ------------- ------ ------ chr2:152252304-152252384 1.0000 80 chr16:75164518-75164598 1.0000 80 chr3:52274730-52274810 1.0000 80 chr10:48482323-48482403 1.0000 80 chr12:51327604-51327684 1.0000 80 chr10:23140056-23140136 1.0000 80 chr6:158255071-158255151 1.0000 80 chr7:66440342-66440422 1.0000 80 chr18:47252681-47252761 1.0000 80 chr20:56032469-56032549 1.0000 80 chr12:49627791-49627871 1.0000 80 chr10:135267226-13526730 1.0000 80 chr20:43485692-43485772 1.0000 80 chr6:33029925-33030005 1.0000 80 chr19:11201115-11201195 1.0000 80 chr19:45109675-45109755 1.0000 80 chr1:228045118-228045198 1.0000 80 chr12:66037952-66038032 1.0000 80 chr14:23197567-23197647 1.0000 80 chr16:75594089-75594169 1.0000 80 chr19:8226184-8226264 1.0000 80 chr1:55505126-55505206 1.0000 80 chr11:5612925-5613005 1.0000 80 chr6:6657902-6657982 1.0000 80 chr6:25726888-25726968 1.0000 80 chr7:157112687-157112767 1.0000 80 chrX:106928359-106928439 1.0000 80 chr10:102106722-10210680 1.0000 80 chr7:145481987-145482067 1.0000 80 chr17:17727041-17727121 1.0000 80 chr10:70314993-70315073 1.0000 80 chr7:75443241-75443321 1.0000 80 chr6:166744283-166744363 1.0000 80 chr2:26205597-26205677 1.0000 80 chr5:55790327-55790407 1.0000 80 chr20:60934267-60934347 1.0000 80 chr7:155090729-155090809 1.0000 80 chr12:116985835-11698591 1.0000 80 chr2:223574248-223574328 1.0000 80 chr10:99174715-99174795 1.0000 80 chr16:27438456-27438536 1.0000 80 chr2:183903204-183903284 1.0000 80 chr3:85553580-85553660 1.0000 80 chr11:65188828-65188908 1.0000 80 chr3:195870335-195870415 1.0000 80 chr11:117778105-11777818 1.0000 80 chr6:36854917-36854997 1.0000 80 chr19:49653077-49653157 1.0000 80 chr6:35331279-35331359 1.0000 80 chrX:38660634-38660714 1.0000 80 chr17:17743510-17743590 1.0000 80 chr11:61582614-61582694 1.0000 80 chr16:67538380-67538460 1.0000 80 chr12:92073839-92073919 1.0000 80 chr4:79550633-79550713 1.0000 80 chr22:38577827-38577907 1.0000 80 chr10:16859702-16859782 1.0000 80 chr9:140188840-140188920 1.0000 80 chr10:102133167-10213324 1.0000 80 chrX:155231392-155231472 1.0000 80 chr8:11660053-11660133 1.0000 80 chr3:177011411-177011491 1.0000 80 chr8:142726268-142726348 1.0000 80 chr5:90676780-90676860 1.0000 80 chr17:35716145-35716225 1.0000 80 chr5:139554675-139554755 1.0000 80 chrX:15511484-15511564 1.0000 80 chr4:111115102-111115182 1.0000 80 chr13:46756384-46756464 1.0000 80 chr9:128845120-128845200 1.0000 80 chr19:50268805-50268885 1.0000 80 chr17:76313748-76313828 1.0000 80 chr22:42228923-42229003 1.0000 80 chr6:126279159-126279239 1.0000 80 chr10:104209461-10420954 1.0000 80 chr3:156806468-156806548 1.0000 80 chr22:23270885-23270965 1.0000 80 chr16:639820-639900 1.0000 80 chr12:125346187-12534626 1.0000 80 chr11:86748919-86748999 1.0000 80 chr4:6675002-6675082 1.0000 80 chr3:197466531-197466611 1.0000 80 chr6:26222943-26223023 1.0000 80 chr1:76250686-76250766 1.0000 80 chr1:1935261-1935341 1.0000 80 chrX:48538991-48539071 1.0000 80 chr7:127739413-127739493 1.0000 80 chr12:1800084-1800164 1.0000 80 chr2:159926349-159926429 1.0000 80 chr8:22927818-22927898 1.0000 80 chr12:100596541-10059662 1.0000 80 chr1:246151935-246152015 1.0000 80 chr19:47730400-47730480 1.0000 80 chr22:23499048-23499128 1.0000 80 chr2:209130811-209130891 1.0000 80 chr2:201677247-201677327 1.0000 80 chr18:21166830-21166910 1.0000 80 chr8:126010526-126010606 1.0000 80 chr11:17229585-17229665 1.0000 80 chr9:124133557-124133637 1.0000 80 chr10:14420676-14420756 1.0000 80 chr17:61920486-61920566 1.0000 80 chr6:15569694-15569774 1.0000 80 chr11:64334206-64334286 1.0000 80 chr11:73490587-73490667 1.0000 80 chr6:53224237-53224317 1.0000 80 chr8:38644572-38644652 1.0000 80 chr14:106267648-10626772 1.0000 80 chr7:26904415-26904495 1.0000 80 chr2:20386395-20386475 1.0000 80 chr2:223725645-223725725 1.0000 80 chr9:114828317-114828397 1.0000 80 chr3:128268275-128268355 1.0000 80 chr6:43905221-43905301 1.0000 80 chr1:167729442-167729522 1.0000 80 chr19:49141643-49141723 1.0000 80 chr17:45266903-45266983 1.0000 80 chr19:42806765-42806845 1.0000 80 chr10:124671558-12467163 1.0000 80 chr1:1677859-1677939 1.0000 80 chr19:49649561-49649641 1.0000 80 chr7:155089390-155089470 1.0000 80 chr22:23623566-23623646 1.0000 80 chr19:6737323-6737403 1.0000 80 chr9:130538769-130538849 1.0000 80 chr22:21993807-21993887 1.0000 80 chr19:18392674-18392754 1.0000 80 chr19:11675739-11675819 1.0000 80 chr9:35489953-35490033 1.0000 80 chr8:26434943-26435023 1.0000 80 chr19:9929790-9929870 1.0000 80 chr19:11308606-11308686 1.0000 80 chr1:156163564-156163644 1.0000 80 chrX:48755458-48755538 1.0000 80 chr17:36956238-36956318 1.0000 80 chr16:4511456-4511536 1.0000 80 chr20:25604627-25604707 1.0000 80 chr15:90727378-90727458 1.0000 80 chrX:48754523-48754603 1.0000 80 chr11:125933004-12593308 1.0000 80 chr5:110848381-110848461 1.0000 80 chr17:46133200-46133280 1.0000 80 chr17:80056173-80056253 1.0000 80 chr19:50354308-50354388 1.0000 80 chr11:61602206-61602286 1.0000 80 chr14:62162033-62162113 1.0000 80 chr16:88627281-88627361 1.0000 80 chr17:7589713-7589793 1.0000 80 chr19:11200031-11200111 1.0000 80 chrX:40506778-40506858 1.0000 80 chr1:1624580-1624660 1.0000 80 chr2:183814421-183814501 1.0000 80 chr19:7627835-7627915 1.0000 80 chr11:6502690-6502770 1.0000 80 chr3:119395922-119396002 1.0000 80 chr22:19167304-19167384 1.0000 80 chr17:55417953-55418033 1.0000 80 chrX:153140943-153141023 1.0000 80 chr6:42518156-42518236 1.0000 80 chr20:49923463-49923543 1.0000 80 chrX:70585886-70585966 1.0000 80 chr10:70883888-70883968 1.0000 80 chr11:71814440-71814520 1.0000 80 chrX:24247656-24247736 1.0000 80 chr12:122681655-12268173 1.0000 80 chr3:165635819-165635899 1.0000 80 chr22:21995891-21995971 1.0000 80 chr2:20298078-20298158 1.0000 80 chr1:236162935-236163015 1.0000 80 chrX:153656930-153657010 1.0000 80 chr1:100828597-100828677 1.0000 80 chr12:108511329-10851140 1.0000 80 chr22:23035442-23035522 1.0000 80 chr4:10175128-10175208 1.0000 80 chr3:43663733-43663813 1.0000 80 chr3:185422268-185422348 1.0000 80 chr20:35012561-35012641 1.0000 80 chr7:154794913-154794993 1.0000 80 chr6:160114505-160114585 1.0000 80 chr19:50179858-50179938 1.0000 80 chr6:76055257-76055337 1.0000 80 chr10:1094908-1094988 1.0000 80 chr22:19803083-19803163 1.0000 80 chr11:82612593-82612673 1.0000 80 chr6:15901735-15901815 1.0000 80 chr5:43313757-43313837 1.0000 80 chr1:38230105-38230185 1.0000 80 chr9:14400814-14400894 1.0000 80 chr3:46951110-46951190 1.0000 80 chr16:71501842-71501922 1.0000 80 chr22:22711756-22711836 1.0000 80 chrX:47479321-47479401 1.0000 80 chr21:44394199-44394279 1.0000 80 chr1:35318401-35318481 1.0000 80 chr7:43909108-43909188 1.0000 80 chr9:126872734-126872814 1.0000 80 chr6:43878534-43878614 1.0000 80 chr11:568675-568755 1.0000 80 chr19:1940768-1940848 1.0000 80 chr17:7137856-7137936 1.0000 80 chr12:125425318-12542539 1.0000 80 chr15:93443506-93443586 1.0000 80 chr4:166248667-166248747 1.0000 80 chr12:56367520-56367600 1.0000 80 chr17:27970524-27970604 1.0000 80 chr8:59465674-59465754 1.0000 80 chr5:89854391-89854471 1.0000 80 chr3:5065162-5065242 1.0000 80 chr14:39901487-39901567 1.0000 80 chr11:70496571-70496651 1.0000 80 chr1:11862809-11862889 1.0000 80 chr5:41883516-41883596 1.0000 80 chr16:47753833-47753913 1.0000 80 chr9:15511046-15511126 1.0000 80 chr15:65118004-65118084 1.0000 80 chr10:103578306-10357838 1.0000 80 chr14:36004540-36004620 1.0000 80 chr14:102180064-10218014 1.0000 80 chr1:32757450-32757530 1.0000 80 chr19:12912679-12912759 1.0000 80 chr7:2595176-2595256 1.0000 80 chr8:10847832-10847912 1.0000 80 chr1:46218363-46218443 1.0000 80 chr1:207925356-207925436 1.0000 80 chr19:57149468-57149548 1.0000 80 chr1:35390563-35390643 1.0000 80 chr22:40384728-40384808 1.0000 80 chr5:176433815-176433895 1.0000 80 chr22:39052477-39052557 1.0000 80 chr11:129872313-12987239 1.0000 80 chr16:2053992-2054072 1.0000 80 chr17:76579370-76579450 1.0000 80 chr22:22020238-22020318 1.0000 80 chr5:168006801-168006881 1.0000 80 chr5:132202187-132202267 1.0000 80 chr10:127511966-12751204 1.0000 80 chr12:48551253-48551333 1.0000 80 chr5:151304261-151304341 1.0000 80 chr19:11205733-11205813 1.0000 80 chr4:42659371-42659451 1.0000 80 chr17:73029934-73030014 1.0000 80 chr17:26904042-26904122 1.0000 80 chr9:88552500-88552580 1.0000 80 chr16:14580886-14580966 1.0000 80 chr15:48653200-48653280 1.0000 80 chr16:68113575-68113655 1.0000 80 chr9:130922148-130922228 1.0000 80 chr1:32253919-32253999 1.0000 80 chr15:68171191-68171271 1.0000 80 chr7:150076242-150076322 1.0000 80 ******************************************************************************** ******************************************************************************** COMMAND LINE SUMMARY ******************************************************************************** This information can also be useful in the event you wish to report a problem with the MEME software. command: meme -oc ../result/final_prediction/K562/inference_raw/MEME/RankLinear0.6_40_SREBF1/ -dna -nmotifs 5 -w 8 -maxsize 250000 -nostatus ../result/final_prediction/K562/fasta/RankLinear0.6_40/SREBF1.fasta model: mod= zoops nmotifs= 5 evt= inf objective function: em= E-value of product of p-values starts= E-value of product of p-values strands: + width: minw= 8 maxw= 8 nsites: minsites= 2 maxsites= 250 wnsites= 0.8 theta: spmap= uni spfuzz= 0.5 em: prior= dirichlet b= 0.01 maxiter= 50 distance= 1e-05 trim: wg= 11 ws= 1 endgaps= yes data: n= 20000 N= 250 sample: seed= 0 hsfrac= 0 searchsize= 20000 norand= no csites= 1000 Letter frequencies in dataset: A 0.201 C 0.296 G 0.31 T 0.193 Background letter frequencies (from file dataset with add-one prior applied): A 0.201 C 0.296 G 0.31 T 0.193 Background model order: 0 ******************************************************************************** ******************************************************************************** MOTIF TCACSYSA MEME-1 width = 8 sites = 96 llr = 751 E-value = 1.9e-055 ******************************************************************************** -------------------------------------------------------------------------------- Motif TCACSYSA MEME-1 Description -------------------------------------------------------------------------------- Simplified A ::a:1::a pos.-specific C :9:7666: probability G :1:33:4: matrix T a::::4:: bits 2.4 * * * 2.1 * * * 1.9 * * * 1.7 * * * Relative 1.4 * * * Entropy 1.2 *** * (11.3 bits) 0.9 *** * * 0.7 **** *** 0.5 ******** 0.2 ******** 0.0 -------- Multilevel TCACCCCA consensus GGTG sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCACSYSA MEME-1 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr3:5065162-5065242 35 1.16e-05 ACGCAGACGG TCACCTCA TGGTGACGTC chr15:90727378-90727458 57 1.16e-05 GGAGCCAAGG TCACCTCA TAAATGCGGG chr6:6657902-6657982 28 1.16e-05 cctcccagca tcacctca ttgcaaaatc chr1:228045118-228045198 46 1.16e-05 cctctcaaca tcacctca ttgcaagatc chr19:45109675-45109755 63 1.16e-05 cctccccaca tcacctca ttacaagatc chr20:43485692-43485772 60 1.16e-05 cctcactgca tcacctca ttgcaaggtc chr10:23140056-23140136 49 1.16e-05 cctcctggca tcacctca ttgtgagatc chr9:130922148-130922228 3 2.93e-05 ga tcacccca ctgcattcca chr17:76579370-76579450 21 2.93e-05 gctcgttggc tcacccca tattggtcac chr22:40384728-40384808 36 2.93e-05 ccacaccacg tcacccca catcacatca chr14:102180064-10218014 11 2.93e-05 cactgtcatc tcacccca ccCACTGAGA chr16:47753833-47753913 73 2.93e-05 agctctagag tcacccca chr1:100828597-100828677 54 2.93e-05 ggaaggctga tcacccca ccctaatctt chr6:42518156-42518236 60 2.93e-05 cccagacaga tcacccca caaaacattc chr19:11200031-11200111 37 2.93e-05 CATTTGAAAA TCACCCCA CTGCAAACTC chr16:88627281-88627361 69 2.93e-05 GGTGCTGAAA TCACCCCA ACAG chr8:26434943-26435023 60 2.93e-05 CTCGGCGCAG TCACCCCA CGCGGGGCTG chr6:53224237-53224317 17 2.93e-05 cccgcggcgg TCACCCCA TTCATTCCGC chrX:48538991-48539071 56 2.93e-05 catcaagaag tcacccca catggtctaa chr6:26222943-26223023 55 2.93e-05 tgagctgaga tcacccca ctgcactcca chr22:42228923-42229003 53 2.93e-05 TGACGCGCCA TCACCCCA CGCACCGCTT chr4:79550633-79550713 49 2.93e-05 ggaaggctgg tcacccca ccctaatctg chr16:67538380-67538460 36 2.93e-05 AGCGCCACGA TCACCCCA GGGGTGGAGC chr11:117778105-11777818 29 2.93e-05 ATCCTCCTCC TCACCCCA CTCTGATGAT chr2:26205597-26205677 27 2.93e-05 CCGCCCGCCG TCACCCCA CCGAGCCCGA chr7:75443241-75443321 70 2.93e-05 GGAGGGGACA TCACCCCA CCT chr7:157112687-157112767 47 2.93e-05 GCCTGGAAGG TCACCCCA GGATCTCATC chr20:56032469-56032549 11 2.93e-05 agccctggcg tcacccca tggcaggatc chr12:51327604-51327684 58 2.93e-05 agctgtggta tcacccca tggcaggatc chr5:41883516-41883596 11 5.35e-05 ctcctgacca tcacctga tagttgccag chr1:35318401-35318481 22 5.35e-05 GGCTCATTTG TCACCTGA CCTCTGTCAG chr22:22711756-22711836 19 5.35e-05 GAGGCTCTGG TCACCTGA TCACAGAACG chr6:15901735-15901815 36 5.35e-05 cacctgatgg tcacctga cactcctggg chrX:153656930-153657010 59 5.35e-05 GGGGCAACGG TCACCTGA TCTGCGGCTG chr6:43905221-43905301 55 5.35e-05 CTGTGGTCAC TCACCTGA CAGACTCCAG chr7:26904415-26904495 42 5.35e-05 TGATGCTGCG TCACCTGA TCCAGCGTCC chr18:21166830-21166910 15 5.35e-05 CCCAACCCAG TCACCTGA AAGGAATCTG chr13:46756384-46756464 69 5.35e-05 CCACCAAAAA TCACCTGA CAGA chr2:183903204-183903284 20 5.35e-05 GGGCCCTCGG TCACCTGA TCGGCAGCGC chr16:75164518-75164598 68 5.35e-05 tgcctgacca tcacctga gggtg chr5:168006801-168006881 39 9.06e-05 TGGGTCTTAG TCACGCCA GCGAGGAGGC chr19:57149468-57149548 7 9.06e-05 GACAGC TCACGCCA GACAGATTCA chr8:59465674-59465754 24 9.06e-05 GGGGACGGGA TCACCCGA CCCGGCGCCG chr12:100596541-10059662 47 9.06e-05 tgagccgaga tcacgcca ctgcactcca chr8:11660053-11660133 5 9.06e-05 GTTA TCACGCCA GTCTCCTTCC chr12:116985835-11698591 46 9.06e-05 TCACTGACAC TCACGCCA CTCTTTGATT chr10:70314993-70315073 15 9.06e-05 agtgagctga tcacgcca ctgcactcaa chr7:145481987-145482067 23 9.06e-05 agccccgaga tcacgcca ctgcaagaat chr6:25726888-25726968 21 9.06e-05 TCATTTGCAT TCACGCCA CTTCCCATTG chr3:185422268-185422348 37 1.11e-04 tggcgtgatc tcagctca ctgcagcctt chr1:167729442-167729522 65 1.11e-04 tggtgtgatc tcagctca ctgcaagc chr3:52274730-52274810 13 1.11e-04 ACTTGTTACA TCAGCTCA GACTAAGCCA chr16:68113575-68113655 63 1.54e-04 GTTTGGCAGA TCACACCA CACAGTCCCT chr15:48653200-48653280 73 1.54e-04 tgggctgaga tcacacca chr5:132202187-132202267 30 1.54e-04 GGTCACCCAG TCAGCCCA CTTCTTTCTG chr17:7137856-7137936 64 1.54e-04 CCCCTCCCAA TCACGTGA CCGTCTGAC chr10:70883888-70883968 50 1.54e-04 CGGCCCGAGG TCACGTGA CGGAGCGCCG chr2:183814421-183814501 55 1.54e-04 tgagtcatga tcacacca ctgcactcca chr9:114828317-114828397 19 1.54e-04 gcaggccgag tcacacca ctagaagacg chr1:246151935-246152015 38 1.54e-04 CCTAATCCAA TCAGCCCA CACCTGGCcc chr12:125346187-12534626 56 1.54e-04 CTTCCTGCCT TCACACCA CTCGGCCCCA chr6:36854917-36854997 71 1.54e-04 cctccccggt tcacacca tt chr10:99174715-99174795 43 1.54e-04 tgagtcatga tcacacca ctgcactccc chr5:55790327-55790407 20 2.07e-04 ACAGAAGGGG TCACATGA TTTATCGGGT chr4:166248667-166248747 52 2.58e-04 TTCGCGCGAG TCACACGA TGTCGGCAAC chr4:10175128-10175208 60 2.58e-04 ccggaggggg tcaggcca ctttcttcaa chr4:111115102-111115182 28 2.58e-04 GGGCACCGTG TCAGCCGA CATCAGAAGA chr20:60934267-60934347 43 2.58e-04 GCCCCCACGG TCAGGCCA CCCAGGGGCC chr14:23197567-23197647 13 2.58e-04 accagaaatg tcaggcca ccatcagatt chr10:135267226-13526730 72 2.58e-04 CTGGTGATGC TCAGGCCA G chr15:68171191-68171271 67 2.79e-04 caggatccaa tcagatca atccct chr14:62162033-62162113 63 3.23e-04 CGCCTCCACC TCAGGTGA GGCGGGCTTG chr1:156163564-156163644 30 3.23e-04 AAACACAAGG TGACCCCA TTTACAACTG chr2:20386395-20386475 37 3.23e-04 ATTGCAGATA TCAGGTGA TCACTGCAGA chr11:64334206-64334286 33 3.23e-04 GGTGATGCAA TCAGGTGA CGCCTAAGGG chr19:47730400-47730480 4 3.23e-04 gac tgacccca cccagatcac chr7:127739413-127739493 14 3.23e-04 CTGCTATGGA TCAGGTGA TACTGATGCA chr3:156806468-156806548 53 3.23e-04 GCTTATAACA TCAGGTGA CGCCTCCAGC chr10:104209461-10420954 43 3.23e-04 cctctcgggc tcaggtga tcctcccatc chr6:126279159-126279239 38 3.23e-04 cgtgctgtgg tcaggtga ttttacagta chr17:76313748-76313828 8 3.23e-04 CTCCCAG TCAGGTGA CTTGCAGGCA chr5:139554675-139554755 35 3.23e-04 GCCAGGGTGA TCAGGTGA CTCCCGGTTC chr3:177011411-177011491 30 3.23e-04 CTCCCAGGAA TCAGGTGA TGTCTCATTA chr7:66440342-66440422 19 3.23e-04 gatcttgtag tcaggtga tgccaggagg chr2:152252304-152252384 63 3.23e-04 tgctatgggg tgacccca gggctcaatc chr19:1940768-1940848 5 3.85e-04 TCCG TGACGTCA GGTGGCGAGA chr11:65188828-65188908 7 3.85e-04 TGAAGG TCAGATGA CACACAGTCA chr12:66037952-66038032 35 3.85e-04 gccagaagca tgacctga ctggatcctg chr7:150076242-150076322 62 4.85e-04 GCCGGGCGGG TCATCTGA GCGGCGCAGC chr11:5612925-5613005 59 4.85e-04 atgcaagggc tcatctga ttagatcctg chr5:43313757-43313837 22 5.30e-04 TGTGAGAGAC TGACGTGA GGTGGCACGA chrX:48755458-48755538 16 5.30e-04 GGACGCTGGA TGAGCCCA TTTCTGAAGT chr6:158255071-158255151 54 5.30e-04 tgccatgggg tgacacca gggcttgatc chr17:27970524-27970604 3 5.55e-04 ct tcatgcca ttctgcttta chr10:14420676-14420756 3 6.15e-04 aa tgacatga tgctgggaag chr12:108511329-10851140 56 6.85e-04 taccgtgggg tgaggcca gggctcaatc -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCACSYSA MEME-1 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr3:5065162-5065242 1.2e-05 34_[+1]_38 chr15:90727378-90727458 1.2e-05 56_[+1]_16 chr6:6657902-6657982 1.2e-05 27_[+1]_45 chr1:228045118-228045198 1.2e-05 45_[+1]_27 chr19:45109675-45109755 1.2e-05 62_[+1]_10 chr20:43485692-43485772 1.2e-05 59_[+1]_13 chr10:23140056-23140136 1.2e-05 48_[+1]_24 chr9:130922148-130922228 2.9e-05 2_[+1]_70 chr17:76579370-76579450 2.9e-05 20_[+1]_52 chr22:40384728-40384808 2.9e-05 35_[+1]_37 chr14:102180064-10218014 2.9e-05 10_[+1]_62 chr16:47753833-47753913 2.9e-05 72_[+1] chr1:100828597-100828677 2.9e-05 53_[+1]_19 chr6:42518156-42518236 2.9e-05 59_[+1]_13 chr19:11200031-11200111 2.9e-05 36_[+1]_36 chr16:88627281-88627361 2.9e-05 68_[+1]_4 chr8:26434943-26435023 2.9e-05 59_[+1]_13 chr6:53224237-53224317 2.9e-05 16_[+1]_56 chrX:48538991-48539071 2.9e-05 55_[+1]_17 chr6:26222943-26223023 2.9e-05 54_[+1]_18 chr22:42228923-42229003 2.9e-05 52_[+1]_20 chr4:79550633-79550713 2.9e-05 48_[+1]_24 chr16:67538380-67538460 2.9e-05 35_[+1]_37 chr11:117778105-11777818 2.9e-05 28_[+1]_44 chr2:26205597-26205677 2.9e-05 26_[+1]_46 chr7:75443241-75443321 2.9e-05 69_[+1]_3 chr7:157112687-157112767 2.9e-05 46_[+1]_26 chr20:56032469-56032549 2.9e-05 10_[+1]_62 chr12:51327604-51327684 2.9e-05 57_[+1]_15 chr5:41883516-41883596 5.3e-05 10_[+1]_62 chr1:35318401-35318481 5.3e-05 21_[+1]_51 chr22:22711756-22711836 5.3e-05 18_[+1]_54 chr6:15901735-15901815 5.3e-05 35_[+1]_37 chrX:153656930-153657010 5.3e-05 58_[+1]_14 chr6:43905221-43905301 5.3e-05 54_[+1]_18 chr7:26904415-26904495 5.3e-05 41_[+1]_31 chr18:21166830-21166910 5.3e-05 14_[+1]_58 chr13:46756384-46756464 5.3e-05 68_[+1]_4 chr2:183903204-183903284 5.3e-05 19_[+1]_53 chr16:75164518-75164598 5.3e-05 67_[+1]_5 chr5:168006801-168006881 9.1e-05 38_[+1]_34 chr19:57149468-57149548 9.1e-05 6_[+1]_66 chr8:59465674-59465754 9.1e-05 23_[+1]_49 chr12:100596541-10059662 9.1e-05 46_[+1]_26 chr8:11660053-11660133 9.1e-05 4_[+1]_68 chr12:116985835-11698591 9.1e-05 45_[+1]_27 chr10:70314993-70315073 9.1e-05 14_[+1]_58 chr7:145481987-145482067 9.1e-05 22_[+1]_50 chr6:25726888-25726968 9.1e-05 20_[+1]_52 chr3:185422268-185422348 0.00011 36_[+1]_36 chr1:167729442-167729522 0.00011 64_[+1]_8 chr3:52274730-52274810 0.00011 12_[+1]_60 chr16:68113575-68113655 0.00015 62_[+1]_10 chr15:48653200-48653280 0.00015 72_[+1] chr5:132202187-132202267 0.00015 29_[+1]_43 chr17:7137856-7137936 0.00015 63_[+1]_9 chr10:70883888-70883968 0.00015 49_[+1]_23 chr2:183814421-183814501 0.00015 54_[+1]_18 chr9:114828317-114828397 0.00015 18_[+1]_54 chr1:246151935-246152015 0.00015 37_[+1]_35 chr12:125346187-12534626 0.00015 55_[+1]_17 chr6:36854917-36854997 0.00015 70_[+1]_2 chr10:99174715-99174795 0.00015 42_[+1]_30 chr5:55790327-55790407 0.00021 19_[+1]_53 chr4:166248667-166248747 0.00026 51_[+1]_21 chr4:10175128-10175208 0.00026 59_[+1]_13 chr4:111115102-111115182 0.00026 27_[+1]_45 chr20:60934267-60934347 0.00026 42_[+1]_30 chr14:23197567-23197647 0.00026 12_[+1]_60 chr10:135267226-13526730 0.00026 71_[+1]_1 chr15:68171191-68171271 0.00028 66_[+1]_6 chr14:62162033-62162113 0.00032 62_[+1]_10 chr1:156163564-156163644 0.00032 29_[+1]_43 chr2:20386395-20386475 0.00032 36_[+1]_36 chr11:64334206-64334286 0.00032 32_[+1]_40 chr19:47730400-47730480 0.00032 3_[+1]_69 chr7:127739413-127739493 0.00032 13_[+1]_59 chr3:156806468-156806548 0.00032 52_[+1]_20 chr10:104209461-10420954 0.00032 42_[+1]_30 chr6:126279159-126279239 0.00032 37_[+1]_35 chr17:76313748-76313828 0.00032 7_[+1]_65 chr5:139554675-139554755 0.00032 34_[+1]_38 chr3:177011411-177011491 0.00032 29_[+1]_43 chr7:66440342-66440422 0.00032 18_[+1]_54 chr2:152252304-152252384 0.00032 62_[+1]_10 chr19:1940768-1940848 0.00038 4_[+1]_68 chr11:65188828-65188908 0.00038 6_[+1]_66 chr12:66037952-66038032 0.00038 34_[+1]_38 chr7:150076242-150076322 0.00049 61_[+1]_11 chr11:5612925-5613005 0.00049 58_[+1]_14 chr5:43313757-43313837 0.00053 21_[+1]_51 chrX:48755458-48755538 0.00053 15_[+1]_57 chr6:158255071-158255151 0.00053 53_[+1]_19 chr17:27970524-27970604 0.00055 2_[+1]_70 chr10:14420676-14420756 0.00062 2_[+1]_70 chr12:108511329-10851140 0.00069 55_[+1]_17 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCACSYSA MEME-1 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF TCACSYSA width=8 seqs=96 chr3:5065162-5065242 ( 35) TCACCTCA 1 chr15:90727378-90727458 ( 57) TCACCTCA 1 chr6:6657902-6657982 ( 28) TCACCTCA 1 chr1:228045118-228045198 ( 46) TCACCTCA 1 chr19:45109675-45109755 ( 63) TCACCTCA 1 chr20:43485692-43485772 ( 60) TCACCTCA 1 chr10:23140056-23140136 ( 49) TCACCTCA 1 chr9:130922148-130922228 ( 3) TCACCCCA 1 chr17:76579370-76579450 ( 21) TCACCCCA 1 chr22:40384728-40384808 ( 36) TCACCCCA 1 chr14:102180064-10218014 ( 11) TCACCCCA 1 chr16:47753833-47753913 ( 73) TCACCCCA 1 chr1:100828597-100828677 ( 54) TCACCCCA 1 chr6:42518156-42518236 ( 60) TCACCCCA 1 chr19:11200031-11200111 ( 37) TCACCCCA 1 chr16:88627281-88627361 ( 69) TCACCCCA 1 chr8:26434943-26435023 ( 60) TCACCCCA 1 chr6:53224237-53224317 ( 17) TCACCCCA 1 chrX:48538991-48539071 ( 56) TCACCCCA 1 chr6:26222943-26223023 ( 55) TCACCCCA 1 chr22:42228923-42229003 ( 53) TCACCCCA 1 chr4:79550633-79550713 ( 49) TCACCCCA 1 chr16:67538380-67538460 ( 36) TCACCCCA 1 chr11:117778105-11777818 ( 29) TCACCCCA 1 chr2:26205597-26205677 ( 27) TCACCCCA 1 chr7:75443241-75443321 ( 70) TCACCCCA 1 chr7:157112687-157112767 ( 47) TCACCCCA 1 chr20:56032469-56032549 ( 11) TCACCCCA 1 chr12:51327604-51327684 ( 58) TCACCCCA 1 chr5:41883516-41883596 ( 11) TCACCTGA 1 chr1:35318401-35318481 ( 22) TCACCTGA 1 chr22:22711756-22711836 ( 19) TCACCTGA 1 chr6:15901735-15901815 ( 36) TCACCTGA 1 chrX:153656930-153657010 ( 59) TCACCTGA 1 chr6:43905221-43905301 ( 55) TCACCTGA 1 chr7:26904415-26904495 ( 42) TCACCTGA 1 chr18:21166830-21166910 ( 15) TCACCTGA 1 chr13:46756384-46756464 ( 69) TCACCTGA 1 chr2:183903204-183903284 ( 20) TCACCTGA 1 chr16:75164518-75164598 ( 68) TCACCTGA 1 chr5:168006801-168006881 ( 39) TCACGCCA 1 chr19:57149468-57149548 ( 7) TCACGCCA 1 chr8:59465674-59465754 ( 24) TCACCCGA 1 chr12:100596541-10059662 ( 47) TCACGCCA 1 chr8:11660053-11660133 ( 5) TCACGCCA 1 chr12:116985835-11698591 ( 46) TCACGCCA 1 chr10:70314993-70315073 ( 15) TCACGCCA 1 chr7:145481987-145482067 ( 23) TCACGCCA 1 chr6:25726888-25726968 ( 21) TCACGCCA 1 chr3:185422268-185422348 ( 37) TCAGCTCA 1 chr1:167729442-167729522 ( 65) TCAGCTCA 1 chr3:52274730-52274810 ( 13) TCAGCTCA 1 chr16:68113575-68113655 ( 63) TCACACCA 1 chr15:48653200-48653280 ( 73) TCACACCA 1 chr5:132202187-132202267 ( 30) TCAGCCCA 1 chr17:7137856-7137936 ( 64) TCACGTGA 1 chr10:70883888-70883968 ( 50) TCACGTGA 1 chr2:183814421-183814501 ( 55) TCACACCA 1 chr9:114828317-114828397 ( 19) TCACACCA 1 chr1:246151935-246152015 ( 38) TCAGCCCA 1 chr12:125346187-12534626 ( 56) TCACACCA 1 chr6:36854917-36854997 ( 71) TCACACCA 1 chr10:99174715-99174795 ( 43) TCACACCA 1 chr5:55790327-55790407 ( 20) TCACATGA 1 chr4:166248667-166248747 ( 52) TCACACGA 1 chr4:10175128-10175208 ( 60) TCAGGCCA 1 chr4:111115102-111115182 ( 28) TCAGCCGA 1 chr20:60934267-60934347 ( 43) TCAGGCCA 1 chr14:23197567-23197647 ( 13) TCAGGCCA 1 chr10:135267226-13526730 ( 72) TCAGGCCA 1 chr15:68171191-68171271 ( 67) TCAGATCA 1 chr14:62162033-62162113 ( 63) TCAGGTGA 1 chr1:156163564-156163644 ( 30) TGACCCCA 1 chr2:20386395-20386475 ( 37) TCAGGTGA 1 chr11:64334206-64334286 ( 33) TCAGGTGA 1 chr19:47730400-47730480 ( 4) TGACCCCA 1 chr7:127739413-127739493 ( 14) TCAGGTGA 1 chr3:156806468-156806548 ( 53) TCAGGTGA 1 chr10:104209461-10420954 ( 43) TCAGGTGA 1 chr6:126279159-126279239 ( 38) TCAGGTGA 1 chr17:76313748-76313828 ( 8) TCAGGTGA 1 chr5:139554675-139554755 ( 35) TCAGGTGA 1 chr3:177011411-177011491 ( 30) TCAGGTGA 1 chr7:66440342-66440422 ( 19) TCAGGTGA 1 chr2:152252304-152252384 ( 63) TGACCCCA 1 chr19:1940768-1940848 ( 5) TGACGTCA 1 chr11:65188828-65188908 ( 7) TCAGATGA 1 chr12:66037952-66038032 ( 35) TGACCTGA 1 chr7:150076242-150076322 ( 62) TCATCTGA 1 chr11:5612925-5613005 ( 59) TCATCTGA 1 chr5:43313757-43313837 ( 22) TGACGTGA 1 chrX:48755458-48755538 ( 16) TGAGCCCA 1 chr6:158255071-158255151 ( 54) TGACACCA 1 chr17:27970524-27970604 ( 3) TCATGCCA 1 chr10:14420676-14420756 ( 3) TGACATGA 1 chr12:108511329-10851140 ( 56) TGAGGCCA 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCACSYSA MEME-1 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 8.66664 E= 1.9e-055 -1323 -1323 -1323 237 -1323 160 -157 -1323 232 -1323 -1323 -1323 -1323 126 -25 -263 -57 93 -4 -1323 -1323 90 -1323 121 -1323 113 19 -1323 232 -1323 -1323 -1323 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCACSYSA MEME-1 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 96 E= 1.9e-055 0.000000 0.000000 0.000000 1.000000 0.000000 0.895833 0.104167 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.708333 0.260417 0.031250 0.135417 0.562500 0.302083 0.000000 0.000000 0.552083 0.000000 0.447917 0.000000 0.645833 0.354167 0.000000 1.000000 0.000000 0.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCACSYSA MEME-1 regular expression -------------------------------------------------------------------------------- TCA[CG][CG][CT][CG]A -------------------------------------------------------------------------------- Time 4.78 secs. ******************************************************************************** ******************************************************************************** MOTIF TGGSGTGA MEME-2 width = 8 sites = 62 llr = 537 E-value = 5.5e-041 ******************************************************************************** -------------------------------------------------------------------------------- Motif TGGSGTGA MEME-2 Description -------------------------------------------------------------------------------- Simplified A ::11:1:a pos.-specific C :::31::: probability G :a859:a: matrix T a::1:9:: bits 2.4 * 2.1 * * * 1.9 * * * 1.7 ** *** Relative 1.4 ** *** Entropy 1.2 *** **** (12.5 bits) 0.9 *** **** 0.7 *** **** 0.5 *** **** 0.2 ******** 0.0 -------- Multilevel TGGGGTGA consensus C sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGGSGTGA MEME-2 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr1:32253919-32253999 8 2.14e-05 GGAGCAA TGGGGTGA CACAGGAGCA chr19:11205733-11205813 25 2.14e-05 GGTCACCTAG TGGGGTGA TCAGAGGCTC chr17:27970524-27970604 35 2.14e-05 cctgaTTAgc tggggtga agtggcgtga chr3:46951110-46951190 7 2.14e-05 ATGCGG TGGGGTGA CCTGCTTTAC chr9:14400814-14400894 33 2.14e-05 AACATTCTGG TGGGGTGA TATTGCATCA chr6:76055257-76055337 49 2.14e-05 taagattagg tggggtga ccagcctttt chr1:236162935-236163015 65 2.14e-05 GCAGGAAGTC TGGGGTGA CTTTTCTC chr19:9929790-9929870 50 2.14e-05 GTggccgggg tggggtga ggatcggagg chrX:155231392-155231472 28 2.14e-05 GAGTTGCAAA TGGGGTGA TAGGGCGTCA chr17:17743510-17743590 34 2.14e-05 CGGCCCGGAG TGGGGTGA CGCGGCGTCA chrX:38660634-38660714 39 2.14e-05 GGGGCGGTGG TGGGGTGA TTCCAAGGGC chr6:35331279-35331359 18 2.14e-05 ACGGCTCATC TGGGGTGA CTTCTGGGGC chr6:166744283-166744363 25 2.14e-05 AGGGGTGGGG TGGGGTGA CTGCACCCCA chr17:17727041-17727121 22 2.14e-05 GGGCCGGGCA TGGGGTGA GCGCGCGCGG chr11:5612925-5613005 42 2.14e-05 gatcctgcca tggggtga tgcaagggct chr12:66037952-66038032 56 2.14e-05 gatcctgcca tggggtga tgccagagct chr7:66440342-66440422 60 2.14e-05 gatgctgcaa tggggtga tgccagggct chr6:158255071-158255151 9 2.14e-05 tcttgcag tggggtga tgctggaggc chr10:48482323-48482403 29 2.14e-05 gatcctgcca tggggtga taccagagct chr9:88552500-88552580 9 4.19e-05 gagtgcag tggcgtga tcttggctca chr3:185422268-185422348 27 4.19e-05 tgcagtgcag tggcgtga tctcagctca chrX:24247656-24247736 35 4.19e-05 tggagtgcag tggcgtga tcgtgactca chr11:6502690-6502770 50 4.19e-05 CATGCGCCGG TGGCGTGA TGGagcggca chr19:11308606-11308686 53 4.19e-05 TGGCACACGG TGGCGTGA CCGCCGCGCG chr19:18392674-18392754 56 4.19e-05 ACGTCCCGGG TGGCGTGA Tgggcccggg chr17:45266903-45266983 36 4.19e-05 AGGCTGGGCG TGGCGTGA CAGCGCGGGC chr11:17229585-17229665 54 4.19e-05 GCTGCCGGGG TGGCGTGA GCAAGGGAGC chr10:16859702-16859782 42 4.19e-05 GGGAAGTTTG TGGCGTGA CTGTGTAAGG chr6:36854917-36854997 31 4.19e-05 tggagtgcag tggcgtga tctctgctca chr3:195870335-195870415 52 4.19e-05 tggagtgctg tggcgtga tatcggctca chr5:55790327-55790407 62 4.19e-05 GGAAAGCATG TGGCGTGA GGTGACTGTC chr1:55505126-55505206 40 4.19e-05 GGGGCTCTGG TGGCGTGA TCTGCGCGCC chr16:75594089-75594169 42 4.19e-05 TGTCAGGAGA TGGCGTGA GGTTTGTGCT chr6:33029925-33030005 36 4.19e-05 tatatgggca tggcgtga tgaggcattt chr1:46218363-46218443 15 5.52e-05 tgaagtgcag tggtgtga ttggggcggg chr5:43313757-43313837 9 5.52e-05 CGAGGAAG TGGTGTGA GAGACTGACG chr11:61602206-61602286 28 5.52e-05 TCAAAGGCCG TGGTGTGA TGTGAGGAGG chr1:167729442-167729522 55 5.52e-05 cagagtgtag tggtgtga tctcagctca chr2:223574248-223574328 44 5.52e-05 TCAGATGGAG TGGTGTGA CCACTGCAGG chr12:108511329-10851140 10 6.91e-05 atcttgcca tgaggtga taccaggagg chr2:183814421-183814501 1 6.91e-05 . tgaggtga cagaatcgcc chr19:11200031-11200111 16 6.91e-05 CCTCTTGCAG TGAGGTGA AGACATTTGA chr17:35716145-35716225 2 6.91e-05 A TGAGGTGA CTACGTCCGG chr19:8226184-8226264 27 6.91e-05 gatcttgcac tgaggtga tgccgggagg chr2:152252304-152252384 17 6.91e-05 gctcttgcaa tgaggtga tgctgggagg chr17:26904042-26904122 2 8.30e-05 G TGGAGTGA GCGCCCCGCC chr6:43878534-43878614 54 8.30e-05 TCTGGTGACT TGGAGTGA GTGTGTTTCT chr22:19167304-19167384 20 8.30e-05 CCTGTGCTGC TGGAGTGA CATGCTCCTT chr10:14420676-14420756 45 8.30e-05 gatcttgcca tggagtga cacaagggct chr15:48653200-48653280 63 1.17e-04 gaggttgcag tgggctga gatcacacca chr19:57149468-57149548 54 1.25e-04 AGGCAGCTCG TGATGTGA ATGGTTCAGC chr6:43905221-43905301 9 1.45e-04 AAATGAGG TGGCCTGA ATGCCCCTTA chr22:38577827-38577907 29 1.45e-04 GGCCACGTGA TGGCCTGA CCACCGCTCT chr12:125425318-12542539 66 1.67e-04 tgggtggacg tggggaga tcgggaa chr11:73490587-73490667 48 1.67e-04 AGCAGACCAA TGGGGAGA GGCAAGGGGC chr20:60934267-60934347 20 1.67e-04 CCTCCTCTGC TGGGGAGA GCCCCGCCCC chr14:23197567-23197647 32 1.89e-04 catcagatta tggtctga cagctgtcac chr19:1940768-1940848 15 2.10e-04 TGACGTCAGG TGGCGAGA CTGTGACGTA chr6:26222943-26223023 45 2.24e-04 gagctaacag tgagctga gatcacccca chr10:70314993-70315073 7 2.24e-04 ttgcag tgagctga tcacgccact chr10:99174715-99174795 28 2.71e-04 gagctcaggc tgcggtga gtcatgatca chr2:20386395-20386475 12 3.21e-04 GGGCAGAGGG AGGGGTGA CAGACTCATT -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGGSGTGA MEME-2 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr1:32253919-32253999 2.1e-05 7_[+2]_65 chr19:11205733-11205813 2.1e-05 24_[+2]_48 chr17:27970524-27970604 2.1e-05 34_[+2]_38 chr3:46951110-46951190 2.1e-05 6_[+2]_66 chr9:14400814-14400894 2.1e-05 32_[+2]_40 chr6:76055257-76055337 2.1e-05 48_[+2]_24 chr1:236162935-236163015 2.1e-05 64_[+2]_8 chr19:9929790-9929870 2.1e-05 49_[+2]_23 chrX:155231392-155231472 2.1e-05 27_[+2]_45 chr17:17743510-17743590 2.1e-05 33_[+2]_39 chrX:38660634-38660714 2.1e-05 38_[+2]_34 chr6:35331279-35331359 2.1e-05 17_[+2]_55 chr6:166744283-166744363 2.1e-05 24_[+2]_48 chr17:17727041-17727121 2.1e-05 21_[+2]_51 chr11:5612925-5613005 2.1e-05 41_[+2]_31 chr12:66037952-66038032 2.1e-05 55_[+2]_17 chr7:66440342-66440422 2.1e-05 59_[+2]_13 chr6:158255071-158255151 2.1e-05 8_[+2]_64 chr10:48482323-48482403 2.1e-05 28_[+2]_44 chr9:88552500-88552580 4.2e-05 8_[+2]_64 chr3:185422268-185422348 4.2e-05 26_[+2]_46 chrX:24247656-24247736 4.2e-05 34_[+2]_38 chr11:6502690-6502770 4.2e-05 49_[+2]_23 chr19:11308606-11308686 4.2e-05 52_[+2]_20 chr19:18392674-18392754 4.2e-05 55_[+2]_17 chr17:45266903-45266983 4.2e-05 35_[+2]_37 chr11:17229585-17229665 4.2e-05 53_[+2]_19 chr10:16859702-16859782 4.2e-05 41_[+2]_31 chr6:36854917-36854997 4.2e-05 30_[+2]_42 chr3:195870335-195870415 4.2e-05 51_[+2]_21 chr5:55790327-55790407 4.2e-05 61_[+2]_11 chr1:55505126-55505206 4.2e-05 39_[+2]_33 chr16:75594089-75594169 4.2e-05 41_[+2]_31 chr6:33029925-33030005 4.2e-05 35_[+2]_37 chr1:46218363-46218443 5.5e-05 14_[+2]_58 chr5:43313757-43313837 5.5e-05 8_[+2]_64 chr11:61602206-61602286 5.5e-05 27_[+2]_45 chr1:167729442-167729522 5.5e-05 54_[+2]_18 chr2:223574248-223574328 5.5e-05 43_[+2]_29 chr12:108511329-10851140 6.9e-05 9_[+2]_63 chr2:183814421-183814501 6.9e-05 [+2]_72 chr19:11200031-11200111 6.9e-05 15_[+2]_57 chr17:35716145-35716225 6.9e-05 1_[+2]_71 chr19:8226184-8226264 6.9e-05 26_[+2]_46 chr2:152252304-152252384 6.9e-05 16_[+2]_56 chr17:26904042-26904122 8.3e-05 1_[+2]_71 chr6:43878534-43878614 8.3e-05 53_[+2]_19 chr22:19167304-19167384 8.3e-05 19_[+2]_53 chr10:14420676-14420756 8.3e-05 44_[+2]_28 chr15:48653200-48653280 0.00012 62_[+2]_10 chr19:57149468-57149548 0.00013 53_[+2]_19 chr6:43905221-43905301 0.00014 8_[+2]_64 chr22:38577827-38577907 0.00014 28_[+2]_44 chr12:125425318-12542539 0.00017 65_[+2]_7 chr11:73490587-73490667 0.00017 47_[+2]_25 chr20:60934267-60934347 0.00017 19_[+2]_53 chr14:23197567-23197647 0.00019 31_[+2]_41 chr19:1940768-1940848 0.00021 14_[+2]_58 chr6:26222943-26223023 0.00022 44_[+2]_28 chr10:70314993-70315073 0.00022 6_[+2]_66 chr10:99174715-99174795 0.00027 27_[+2]_45 chr2:20386395-20386475 0.00032 11_[+2]_61 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGGSGTGA MEME-2 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF TGGSGTGA width=8 seqs=62 chr1:32253919-32253999 ( 8) TGGGGTGA 1 chr19:11205733-11205813 ( 25) TGGGGTGA 1 chr17:27970524-27970604 ( 35) TGGGGTGA 1 chr3:46951110-46951190 ( 7) TGGGGTGA 1 chr9:14400814-14400894 ( 33) TGGGGTGA 1 chr6:76055257-76055337 ( 49) TGGGGTGA 1 chr1:236162935-236163015 ( 65) TGGGGTGA 1 chr19:9929790-9929870 ( 50) TGGGGTGA 1 chrX:155231392-155231472 ( 28) TGGGGTGA 1 chr17:17743510-17743590 ( 34) TGGGGTGA 1 chrX:38660634-38660714 ( 39) TGGGGTGA 1 chr6:35331279-35331359 ( 18) TGGGGTGA 1 chr6:166744283-166744363 ( 25) TGGGGTGA 1 chr17:17727041-17727121 ( 22) TGGGGTGA 1 chr11:5612925-5613005 ( 42) TGGGGTGA 1 chr12:66037952-66038032 ( 56) TGGGGTGA 1 chr7:66440342-66440422 ( 60) TGGGGTGA 1 chr6:158255071-158255151 ( 9) TGGGGTGA 1 chr10:48482323-48482403 ( 29) TGGGGTGA 1 chr9:88552500-88552580 ( 9) TGGCGTGA 1 chr3:185422268-185422348 ( 27) TGGCGTGA 1 chrX:24247656-24247736 ( 35) TGGCGTGA 1 chr11:6502690-6502770 ( 50) TGGCGTGA 1 chr19:11308606-11308686 ( 53) TGGCGTGA 1 chr19:18392674-18392754 ( 56) TGGCGTGA 1 chr17:45266903-45266983 ( 36) TGGCGTGA 1 chr11:17229585-17229665 ( 54) TGGCGTGA 1 chr10:16859702-16859782 ( 42) TGGCGTGA 1 chr6:36854917-36854997 ( 31) TGGCGTGA 1 chr3:195870335-195870415 ( 52) TGGCGTGA 1 chr5:55790327-55790407 ( 62) TGGCGTGA 1 chr1:55505126-55505206 ( 40) TGGCGTGA 1 chr16:75594089-75594169 ( 42) TGGCGTGA 1 chr6:33029925-33030005 ( 36) TGGCGTGA 1 chr1:46218363-46218443 ( 15) TGGTGTGA 1 chr5:43313757-43313837 ( 9) TGGTGTGA 1 chr11:61602206-61602286 ( 28) TGGTGTGA 1 chr1:167729442-167729522 ( 55) TGGTGTGA 1 chr2:223574248-223574328 ( 44) TGGTGTGA 1 chr12:108511329-10851140 ( 10) TGAGGTGA 1 chr2:183814421-183814501 ( 1) TGAGGTGA 1 chr19:11200031-11200111 ( 16) TGAGGTGA 1 chr17:35716145-35716225 ( 2) TGAGGTGA 1 chr19:8226184-8226264 ( 27) TGAGGTGA 1 chr2:152252304-152252384 ( 17) TGAGGTGA 1 chr17:26904042-26904122 ( 2) TGGAGTGA 1 chr6:43878534-43878614 ( 54) TGGAGTGA 1 chr22:19167304-19167384 ( 20) TGGAGTGA 1 chr10:14420676-14420756 ( 45) TGGAGTGA 1 chr15:48653200-48653280 ( 63) TGGGCTGA 1 chr19:57149468-57149548 ( 54) TGATGTGA 1 chr6:43905221-43905301 ( 9) TGGCCTGA 1 chr22:38577827-38577907 ( 29) TGGCCTGA 1 chr12:125425318-12542539 ( 66) TGGGGAGA 1 chr11:73490587-73490667 ( 48) TGGGGAGA 1 chr20:60934267-60934347 ( 20) TGGGGAGA 1 chr14:23197567-23197647 ( 32) TGGTCTGA 1 chr19:1940768-1940848 ( 15) TGGCGAGA 1 chr6:26222943-26223023 ( 45) TGAGCTGA 1 chr10:70314993-70315073 ( 7) TGAGCTGA 1 chr10:99174715-99174795 ( 28) TGCGGTGA 1 chr2:20386395-20386475 ( 12) AGGGGTGA 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGGSGTGA MEME-2 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 9.49826 E= 5.5e-041 -363 -1260 -1260 235 -1260 -1260 169 -1260 -47 -419 143 -1260 -164 -3 78 -77 -1260 -161 154 -1260 -164 -1260 -1260 228 -1260 -1260 169 -1260 232 -1260 -1260 -1260 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGGSGTGA MEME-2 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 62 E= 5.5e-041 0.016129 0.000000 0.000000 0.983871 0.000000 0.000000 1.000000 0.000000 0.145161 0.016129 0.838710 0.000000 0.064516 0.290323 0.532258 0.112903 0.000000 0.096774 0.903226 0.000000 0.064516 0.000000 0.000000 0.935484 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGGSGTGA MEME-2 regular expression -------------------------------------------------------------------------------- TGG[GC]GTGA -------------------------------------------------------------------------------- Time 8.33 secs. ******************************************************************************** ******************************************************************************** MOTIF AATCWGAT MEME-3 width = 8 sites = 26 llr = 238 E-value = 3.3e-005 ******************************************************************************** -------------------------------------------------------------------------------- Motif AATCWGAT MEME-3 Description -------------------------------------------------------------------------------- Simplified A 79:15:a: pos.-specific C 1::9:1:: probability G 21:::9:1 matrix T ::a:5::9 bits 2.4 * * 2.1 * * 1.9 ** ** 1.7 ** ** Relative 1.4 **** ** Entropy 1.2 ******* (13.2 bits) 0.9 ******** 0.7 ******** 0.5 ******** 0.2 ******** 0.0 -------- Multilevel AATCAGAT consensus T sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AATCWGAT MEME-3 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr16:47753833-47753913 53 5.58e-06 tctaggatcc aatcagat cgagctctag chr6:25726888-25726968 42 5.58e-06 CCCATTGTCC AATCAGAT TTTGGATACC chr6:6657902-6657982 47 5.58e-06 tgcaaaatcc aatcagat catgcctcat chr1:55505126-55505206 9 5.58e-06 TAATGTTT AATCAGAT AGGATCGTCC chr1:228045118-228045198 65 5.58e-06 tgcaagatcc aatcagat catgcctc chr20:56032469-56032549 71 5.58e-06 gggaacagcc aatcagat ca chr10:23140056-23140136 68 5.58e-06 tgtgagatcc aatcagat cacac chr12:108511329-10851140 70 1.09e-05 gccagggctc aatctgat tgg chr10:14420676-14420756 64 1.09e-05 acaagggctc aatctgat tggatcttg chr4:79550633-79550713 61 1.09e-05 accccaccct aatctgat tatgcaaatg chr12:51327604-51327684 38 1.95e-05 atccatgacc gatcagat caagctgtgg chr11:5612925-5613005 22 2.78e-05 tgggagacat gatctgat tggatcctgc chr19:8226184-8226264 48 2.78e-05 cgggaggcat gatctgat tggatccggc chr6:158255071-158255151 68 2.78e-05 accagggctt gatctgat cggat chr6:76055257-76055337 37 3.16e-05 ccatttgcat aataagat taggtggggt chr6:33029925-33030005 70 3.52e-05 tgggggacat aatatgat cac chr19:45109675-45109755 2 4.06e-05 c aatcacat tgagccctgg chr14:23197567-23197647 22 5.39e-05 gtcaggccac catcagat tatggtctga chr2:209130811-209130891 65 6.52e-05 TCTGCCTGAG CATCTGAT CCGAGCGT chr1:100828597-100828677 66 6.86e-05 accccaccct aatcttat tatgcaa chr2:223574248-223574328 32 7.39e-05 CTTTATTTGT TATCAGAT GGAGTGGTGT chr20:43485692-43485772 38 9.66e-05 gacaggatcc agtcagat tgggcctcac chr16:14580886-14580966 19 1.14e-04 GGGGTGGTCC AGTCTGAT CCCAACCGGC chr22:42228923-42229003 24 1.14e-04 TCACTATGCA AATCTGAG CTGCTGATCG chr3:177011411-177011491 54 1.14e-04 ATTAGTACAC AATCTGAG CACTGAAGAG chr16:75594089-75594169 19 1.33e-04 aGCCCTGAAG GATCACAT TGCAGTGTCA -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AATCWGAT MEME-3 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr16:47753833-47753913 5.6e-06 52_[+3]_20 chr6:25726888-25726968 5.6e-06 41_[+3]_31 chr6:6657902-6657982 5.6e-06 46_[+3]_26 chr1:55505126-55505206 5.6e-06 8_[+3]_64 chr1:228045118-228045198 5.6e-06 64_[+3]_8 chr20:56032469-56032549 5.6e-06 70_[+3]_2 chr10:23140056-23140136 5.6e-06 67_[+3]_5 chr12:108511329-10851140 1.1e-05 69_[+3]_3 chr10:14420676-14420756 1.1e-05 63_[+3]_9 chr4:79550633-79550713 1.1e-05 60_[+3]_12 chr12:51327604-51327684 2e-05 37_[+3]_35 chr11:5612925-5613005 2.8e-05 21_[+3]_51 chr19:8226184-8226264 2.8e-05 47_[+3]_25 chr6:158255071-158255151 2.8e-05 67_[+3]_5 chr6:76055257-76055337 3.2e-05 36_[+3]_36 chr6:33029925-33030005 3.5e-05 69_[+3]_3 chr19:45109675-45109755 4.1e-05 1_[+3]_71 chr14:23197567-23197647 5.4e-05 21_[+3]_51 chr2:209130811-209130891 6.5e-05 64_[+3]_8 chr1:100828597-100828677 6.9e-05 65_[+3]_7 chr2:223574248-223574328 7.4e-05 31_[+3]_41 chr20:43485692-43485772 9.7e-05 37_[+3]_35 chr16:14580886-14580966 0.00011 18_[+3]_54 chr22:42228923-42229003 0.00011 23_[+3]_49 chr3:177011411-177011491 0.00011 53_[+3]_19 chr16:75594089-75594169 0.00013 18_[+3]_54 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AATCWGAT MEME-3 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF AATCWGAT width=8 seqs=26 chr16:47753833-47753913 ( 53) AATCAGAT 1 chr6:25726888-25726968 ( 42) AATCAGAT 1 chr6:6657902-6657982 ( 47) AATCAGAT 1 chr1:55505126-55505206 ( 9) AATCAGAT 1 chr1:228045118-228045198 ( 65) AATCAGAT 1 chr20:56032469-56032549 ( 71) AATCAGAT 1 chr10:23140056-23140136 ( 68) AATCAGAT 1 chr12:108511329-10851140 ( 70) AATCTGAT 1 chr10:14420676-14420756 ( 64) AATCTGAT 1 chr4:79550633-79550713 ( 61) AATCTGAT 1 chr12:51327604-51327684 ( 38) GATCAGAT 1 chr11:5612925-5613005 ( 22) GATCTGAT 1 chr19:8226184-8226264 ( 48) GATCTGAT 1 chr6:158255071-158255151 ( 68) GATCTGAT 1 chr6:76055257-76055337 ( 37) AATAAGAT 1 chr6:33029925-33030005 ( 70) AATATGAT 1 chr19:45109675-45109755 ( 2) AATCACAT 1 chr14:23197567-23197647 ( 22) CATCAGAT 1 chr2:209130811-209130891 ( 65) CATCTGAT 1 chr1:100828597-100828677 ( 66) AATCTTAT 1 chr2:223574248-223574328 ( 32) TATCAGAT 1 chr20:43485692-43485772 ( 38) AGTCAGAT 1 chr16:14580886-14580966 ( 19) AGTCTGAT 1 chr22:42228923-42229003 ( 24) AATCTGAG 1 chr3:177011411-177011491 ( 54) AATCTGAG 1 chr16:75594089-75594169 ( 19) GATCACAT 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AATCWGAT MEME-3 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 10.6186 E= 3.3e-005 179 -194 -69 -233 220 -1134 -201 -1134 -1134 -1134 -1134 237 -138 164 -1134 -1134 142 -1134 -1134 126 -1134 -194 151 -233 232 -1134 -1134 -1134 -1134 -1134 -201 226 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AATCWGAT MEME-3 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 26 E= 3.3e-005 0.692308 0.076923 0.192308 0.038462 0.923077 0.000000 0.076923 0.000000 0.000000 0.000000 0.000000 1.000000 0.076923 0.923077 0.000000 0.000000 0.538462 0.000000 0.000000 0.461538 0.000000 0.076923 0.884615 0.038462 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.076923 0.923077 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AATCWGAT MEME-3 regular expression -------------------------------------------------------------------------------- AATC[AT]GAT -------------------------------------------------------------------------------- Time 11.76 secs. ******************************************************************************** ******************************************************************************** MOTIF TCACTGCA MEME-4 width = 8 sites = 16 llr = 165 E-value = 2.5e-004 ******************************************************************************** -------------------------------------------------------------------------------- Motif TCACTGCA MEME-4 Description -------------------------------------------------------------------------------- Simplified A :1a::::9 pos.-specific C :9:9::a: probability G :1:::a:: matrix T a::1a::1 bits 2.4 * * * 2.1 * * * 1.9 * * * * 1.7 * * **** Relative 1.4 * ****** Entropy 1.2 ******** (14.9 bits) 0.9 ******** 0.7 ******** 0.5 ******** 0.2 ******** 0.0 -------- Multilevel TCACTGCA consensus sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCACTGCA MEME-4 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr9:88552500-88552580 24 1.21e-05 tgatcttggc tcactgca agctccgccc chr17:76579370-76579450 60 1.21e-05 tggtcacatc tcactgca caggaggctg chr1:46218363-46218443 35 1.21e-05 ggggcggggc tcactgca gccttgactt chr17:27970524-27970604 60 1.21e-05 tgatctcaac tcactgca acctttgcac chr19:11675739-11675819 64 1.21e-05 tgatcatgac tcactgca ggcttgacc chr2:20386395-20386475 45 1.21e-05 TATCAGGTGA TCACTGCA GATATCATGT chr2:159926349-159926429 4 1.21e-05 ggc tcactgca tccttgacct chr12:92073839-92073919 6 1.21e-05 tcggc tcactgca agctccgcct chr6:36854917-36854997 46 1.21e-05 tgatctctgc tcactgca agctccgcct chr3:195870335-195870415 67 1.21e-05 tgatatcggc tcactgca accccc chr20:43485692-43485772 52 1.21e-05 agattgggcc tcactgca tcacctcatt chr7:127739413-127739493 1 2.37e-05 . TCACTGCT ATGGATCAGG chr3:85553580-85553660 7 2.37e-05 gggttg tcactgct gctcgggcag chr14:39901487-39901567 43 3.19e-05 GCACACTGAG TAACTGCA CTGCCCTCGC chrX:24247656-24247736 50 3.98e-05 tgatcgtgac tcattgca gtcttgacct chr1:35318401-35318481 68 5.25e-05 CCCAGGGAAG TGACTGCA GGCTT -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCACTGCA MEME-4 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr9:88552500-88552580 1.2e-05 23_[+4]_49 chr17:76579370-76579450 1.2e-05 59_[+4]_13 chr1:46218363-46218443 1.2e-05 34_[+4]_38 chr17:27970524-27970604 1.2e-05 59_[+4]_13 chr19:11675739-11675819 1.2e-05 63_[+4]_9 chr2:20386395-20386475 1.2e-05 44_[+4]_28 chr2:159926349-159926429 1.2e-05 3_[+4]_69 chr12:92073839-92073919 1.2e-05 5_[+4]_67 chr6:36854917-36854997 1.2e-05 45_[+4]_27 chr3:195870335-195870415 1.2e-05 66_[+4]_6 chr20:43485692-43485772 1.2e-05 51_[+4]_21 chr7:127739413-127739493 2.4e-05 [+4]_72 chr3:85553580-85553660 2.4e-05 6_[+4]_66 chr14:39901487-39901567 3.2e-05 42_[+4]_30 chrX:24247656-24247736 4e-05 49_[+4]_23 chr1:35318401-35318481 5.2e-05 67_[+4]_5 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCACTGCA MEME-4 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF TCACTGCA width=8 seqs=16 chr9:88552500-88552580 ( 24) TCACTGCA 1 chr17:76579370-76579450 ( 60) TCACTGCA 1 chr1:46218363-46218443 ( 35) TCACTGCA 1 chr17:27970524-27970604 ( 60) TCACTGCA 1 chr19:11675739-11675819 ( 64) TCACTGCA 1 chr2:20386395-20386475 ( 45) TCACTGCA 1 chr2:159926349-159926429 ( 4) TCACTGCA 1 chr12:92073839-92073919 ( 6) TCACTGCA 1 chr6:36854917-36854997 ( 46) TCACTGCA 1 chr3:195870335-195870415 ( 67) TCACTGCA 1 chr20:43485692-43485772 ( 52) TCACTGCA 1 chr7:127739413-127739493 ( 1) TCACTGCT 1 chr3:85553580-85553660 ( 7) TCACTGCT 1 chr14:39901487-39901567 ( 43) TAACTGCA 1 chrX:24247656-24247736 ( 50) TCATTGCA 1 chr1:35318401-35318481 ( 68) TGACTGCA 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCACTGCA MEME-4 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 10.1543 E= 2.5e-004 -1064 -1064 -1064 237 -168 156 -231 -1064 232 -1064 -1064 -1064 -1064 166 -1064 -163 -1064 -1064 -1064 237 -1064 -1064 169 -1064 -1064 176 -1064 -1064 212 -1064 -1064 -63 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCACTGCA MEME-4 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 16 E= 2.5e-004 0.000000 0.000000 0.000000 1.000000 0.062500 0.875000 0.062500 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.937500 0.000000 0.062500 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.875000 0.000000 0.000000 0.125000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCACTGCA MEME-4 regular expression -------------------------------------------------------------------------------- TCACTGCA -------------------------------------------------------------------------------- Time 15.16 secs. ******************************************************************************** ******************************************************************************** MOTIF GCCAATSR MEME-5 width = 8 sites = 26 llr = 229 E-value = 6.1e-001 ******************************************************************************** -------------------------------------------------------------------------------- Motif GCCAATSR MEME-5 Description -------------------------------------------------------------------------------- Simplified A 2::aa::6 pos.-specific C :aa:::5: probability G 6:::::54 matrix T 2::::a:: bits 2.4 * * 2.1 *** 1.9 *** 1.7 ***** Relative 1.4 ***** Entropy 1.2 ***** * (12.7 bits) 0.9 ***** * 0.7 ******* 0.5 ******** 0.2 ******** 0.0 -------- Multilevel GCCAATCA consensus A GG sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GCCAATSR MEME-5 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr8:11660053-11660133 64 1.26e-05 AGCGGCCCTG GCCAATCA GCGCCCGTC chr10:102133167-10213324 56 1.26e-05 CCACGCCGGA GCCAATCA GCGGCCCCCA chr22:38577827-38577907 49 1.26e-05 ACCGCTCTCC GCCAATCA CTGGTGGCCC chr17:17727041-17727121 39 1.26e-05 AGCGCGCGCG GCCAATCA GCGGCCGCGC chrX:106928359-106928439 46 1.26e-05 TCTGTGGACG GCCAATCA CAAGAGCCAC chr5:43313757-43313837 50 2.58e-05 GAGCCCAGTT GCCAATGA CGGAGCTGCG chr17:80056173-80056253 28 2.58e-05 CGCCGCCCAG GCCAATGA GCGTCGGGGC chr6:53224237-53224317 45 3.40e-05 GGCTGCACCC ACCAATCA CCGCTCACCA chr4:6675002-6675082 69 3.40e-05 ttgtaaacgc accaatca gcac chr7:145481987-145482067 40 4.18e-05 actgcaagaa tccaatca agggaaagag chr6:6657902-6657982 3 4.18e-05 ga tccaatca gattatgcct chr1:228045118-228045198 21 4.18e-05 catggcggga tccaatca aatcgcgcct chr19:45109675-45109755 38 4.18e-05 cagggcacgg tccaatca aatcatgcct chr10:23140056-23140136 24 4.18e-05 catggcagga tccaatca gctcatgcct chr11:61602206-61602286 46 5.04e-05 TGTGAGGAGG ACCAATGA AGGGGCTTTT chr4:166248667-166248747 14 9.84e-05 CATCCGCGGA GCCAATGG CTGGGACCGC chrX:153656930-153657010 18 9.84e-05 CCGCGCTGGG GCCAATGG AGGTGCGAGG chr2:223725645-223725725 33 9.84e-05 CCGCTCGCGG GCCAATGG GTGGCAGCCT chr16:639820-639900 34 9.84e-05 GTGCAGACAG GCCAATGG CTGAGGGAAG chr9:140188840-140188920 50 9.84e-05 ctacgttcta gccaatgg gatgtgagca chr17:17743510-17743590 11 9.84e-05 gcccggcgcA GCCAATGG GCGCCCGGCC chr10:102106722-10210680 38 9.84e-05 ATTGCGCCGA GCCAATGG CAACGGCAGG chr11:61582614-61582694 68 1.11e-04 ACACATACGG ACCAATCG CCGTC chr5:168006801-168006881 58 1.36e-04 CGAGGAGGCG ACCAATGG TGACTGAGAT chr11:71814440-71814520 32 1.36e-04 ATCGTTGTCA ACCAATGG GAAGGCGTAA chr9:88552500-88552580 53 1.61e-04 ccaggtccac gccattca cctgctgagg -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GCCAATSR MEME-5 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr8:11660053-11660133 1.3e-05 63_[+5]_9 chr10:102133167-10213324 1.3e-05 55_[+5]_17 chr22:38577827-38577907 1.3e-05 48_[+5]_24 chr17:17727041-17727121 1.3e-05 38_[+5]_34 chrX:106928359-106928439 1.3e-05 45_[+5]_27 chr5:43313757-43313837 2.6e-05 49_[+5]_23 chr17:80056173-80056253 2.6e-05 27_[+5]_45 chr6:53224237-53224317 3.4e-05 44_[+5]_28 chr4:6675002-6675082 3.4e-05 68_[+5]_4 chr7:145481987-145482067 4.2e-05 39_[+5]_33 chr6:6657902-6657982 4.2e-05 2_[+5]_70 chr1:228045118-228045198 4.2e-05 20_[+5]_52 chr19:45109675-45109755 4.2e-05 37_[+5]_35 chr10:23140056-23140136 4.2e-05 23_[+5]_49 chr11:61602206-61602286 5e-05 45_[+5]_27 chr4:166248667-166248747 9.8e-05 13_[+5]_59 chrX:153656930-153657010 9.8e-05 17_[+5]_55 chr2:223725645-223725725 9.8e-05 32_[+5]_40 chr16:639820-639900 9.8e-05 33_[+5]_39 chr9:140188840-140188920 9.8e-05 49_[+5]_23 chr17:17743510-17743590 9.8e-05 10_[+5]_62 chr10:102106722-10210680 9.8e-05 37_[+5]_35 chr11:61582614-61582694 0.00011 67_[+5]_5 chr5:168006801-168006881 0.00014 57_[+5]_15 chr11:71814440-71814520 0.00014 31_[+5]_41 chr9:88552500-88552580 0.00016 52_[+5]_20 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GCCAATSR MEME-5 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF GCCAATSR width=8 seqs=26 chr8:11660053-11660133 ( 64) GCCAATCA 1 chr10:102133167-10213324 ( 56) GCCAATCA 1 chr22:38577827-38577907 ( 49) GCCAATCA 1 chr17:17727041-17727121 ( 39) GCCAATCA 1 chrX:106928359-106928439 ( 46) GCCAATCA 1 chr5:43313757-43313837 ( 50) GCCAATGA 1 chr17:80056173-80056253 ( 28) GCCAATGA 1 chr6:53224237-53224317 ( 45) ACCAATCA 1 chr4:6675002-6675082 ( 69) ACCAATCA 1 chr7:145481987-145482067 ( 40) TCCAATCA 1 chr6:6657902-6657982 ( 3) TCCAATCA 1 chr1:228045118-228045198 ( 21) TCCAATCA 1 chr19:45109675-45109755 ( 38) TCCAATCA 1 chr10:23140056-23140136 ( 24) TCCAATCA 1 chr11:61602206-61602286 ( 46) ACCAATGA 1 chr4:166248667-166248747 ( 14) GCCAATGG 1 chrX:153656930-153657010 ( 18) GCCAATGG 1 chr2:223725645-223725725 ( 33) GCCAATGG 1 chr16:639820-639900 ( 34) GCCAATGG 1 chr9:140188840-140188920 ( 50) GCCAATGG 1 chr17:17743510-17743590 ( 11) GCCAATGG 1 chr10:102106722-10210680 ( 38) GCCAATGG 1 chr11:61582614-61582694 ( 68) ACCAATCG 1 chr5:168006801-168006881 ( 58) ACCAATGG 1 chr11:71814440-71814520 ( 32) ACCAATGG 1 chr9:88552500-88552580 ( 53) GCCATTCA 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GCCAATSR MEME-5 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 9.98426 E= 6.1e-001 20 -1134 89 -1 -1134 176 -1134 -1134 -1134 176 -1134 -1134 232 -1134 -1134 -1134 226 -1134 -1134 -233 -1134 -1134 -1134 237 -1134 86 57 -1134 162 -1134 31 -1134 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GCCAATSR MEME-5 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 26 E= 6.1e-001 0.230769 0.000000 0.576923 0.192308 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.961538 0.000000 0.000000 0.038462 0.000000 0.000000 0.000000 1.000000 0.000000 0.538462 0.461538 0.000000 0.615385 0.000000 0.384615 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GCCAATSR MEME-5 regular expression -------------------------------------------------------------------------------- [GA]CCAAT[CG][AG] -------------------------------------------------------------------------------- Time 18.55 secs. ******************************************************************************** ******************************************************************************** SUMMARY OF MOTIFS ******************************************************************************** -------------------------------------------------------------------------------- Combined block diagrams: non-overlapping sites with p-value < 0.0001 -------------------------------------------------------------------------------- SEQUENCE NAME COMBINED P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr2:152252304-152252384 1.20e-03 16_[+2(6.91e-05)]_33_[+2(2.14e-05)]_\ 15 chr16:75164518-75164598 1.06e-02 67_[+1(5.35e-05)]_5 chr3:52274730-52274810 2.82e-02 80 chr10:48482323-48482403 1.45e-03 28_[+2(2.14e-05)]_44 chr12:51327604-51327684 1.79e-04 37_[+3(1.95e-05)]_12_[+1(2.93e-05)]_\ 15 chr10:23140056-23140136 4.07e-07 7_[+1(1.16e-05)]_8_[+5(4.18e-05)]_\ 17_[+1(1.16e-05)]_11_[+3(5.58e-06)]_5 chr6:158255071-158255151 1.82e-05 8_[+2(2.14e-05)]_32_[+2(2.14e-05)]_\ 11_[+3(2.78e-05)]_5 chr7:66440342-66440422 2.13e-04 59_[+2(2.14e-05)]_13 chr18:47252681-47252761 3.84e-01 80 chr20:56032469-56032549 3.99e-07 10_[+1(2.93e-05)]_11_[+3(5.58e-06)]_\ 14_[+1(5.35e-05)]_11_[+3(5.58e-06)]_2 chr12:49627791-49627871 4.28e-03 44_[+4(9.37e-05)]_28 chr10:135267226-13526730 7.56e-02 80 chr20:43485692-43485772 3.29e-06 18_[+1(2.93e-05)]_11_[+3(9.66e-05)]_\ 6_[+4(1.21e-05)]_[+1(1.16e-05)]_13 chr6:33029925-33030005 1.09e-03 35_[+2(4.19e-05)]_26_[+3(3.52e-05)]_\ 3 chr19:11201115-11201195 3.01e-01 80 chr19:45109675-45109755 3.32e-06 1_[+3(4.06e-05)]_12_[+1(2.93e-05)]_\ 8_[+5(4.18e-05)]_17_[+1(1.16e-05)]_10 chr1:228045118-228045198 1.32e-08 4_[+1(2.93e-05)]_8_[+5(4.18e-05)]_\ 17_[+1(1.16e-05)]_11_[+3(5.58e-06)]_8 chr12:66037952-66038032 5.24e-04 15_[+2(6.91e-05)]_32_[+2(2.14e-05)]_\ 17 chr14:23197567-23197647 8.46e-05 21_[+3(5.39e-05)]_51 chr16:75594089-75594169 9.99e-04 41_[+2(4.19e-05)]_31 chr19:8226184-8226264 1.02e-04 26_[+2(6.91e-05)]_13_[+3(2.78e-05)]_\ 25 chr1:55505126-55505206 4.13e-04 8_[+3(5.58e-06)]_23_[+2(4.19e-05)]_\ 33 chr11:5612925-5613005 2.91e-05 [+2(6.91e-05)]_13_[+3(2.78e-05)]_12_\ [+2(2.14e-05)]_10_[+3(6.52e-05)]_13 chr6:6657902-6657982 7.04e-08 5_[+3(5.58e-06)]_14_[+1(1.16e-05)]_\ 11_[+3(5.58e-06)]_26 chr6:25726888-25726968 1.49e-05 20_[+1(9.06e-05)]_13_[+3(5.58e-06)]_\ 31 chr7:157112687-157112767 3.74e-03 46_[+1(2.93e-05)]_26 chrX:106928359-106928439 3.47e-03 45_[+5(1.26e-05)]_27 chr10:102106722-10210680 6.89e-02 37_[+5(9.84e-05)]_35 chr7:145481987-145482067 1.62e-05 22_[+1(9.06e-05)]_9_[+5(4.18e-05)]_\ 33 chr17:17727041-17727121 5.27e-04 21_[+2(2.14e-05)]_9_[+5(1.26e-05)]_\ 34 chr10:70314993-70315073 5.54e-04 14_[+1(9.06e-05)]_58 chr7:75443241-75443321 4.19e-02 69_[+1(2.93e-05)]_3 chr6:166744283-166744363 1.02e-03 24_[+2(2.14e-05)]_48 chr2:26205597-26205677 6.75e-02 26_[+1(2.93e-05)]_46 chr5:55790327-55790407 5.72e-04 61_[+2(4.19e-05)]_11 chr20:60934267-60934347 2.47e-02 80 chr7:155090729-155090809 1.97e-01 80 chr12:116985835-11698591 5.15e-02 45_[+1(9.06e-05)]_27 chr2:223574248-223574328 6.17e-05 31_[+3(7.39e-05)]_4_[+2(5.52e-05)]_\ 29 chr10:99174715-99174795 1.85e-03 80 chr16:27438456-27438536 3.15e-02 80 chr2:183903204-183903284 4.45e-02 19_[+1(5.35e-05)]_53 chr3:85553580-85553660 4.51e-02 6_[+4(2.37e-05)]_66 chr11:65188828-65188908 4.59e-03 80 chr3:195870335-195870415 9.02e-04 51_[+2(4.19e-05)]_7_[+4(1.21e-05)]_\ 6 chr11:117778105-11777818 1.36e-04 28_[+1(2.93e-05)]_11_[+4(6.04e-05)]_\ 25 chr6:36854917-36854997 7.46e-05 30_[+2(4.19e-05)]_7_[+4(1.21e-05)]_\ 27 chr19:49653077-49653157 6.29e-01 80 chr6:35331279-35331359 4.29e-03 17_[+2(2.14e-05)]_55 chrX:38660634-38660714 3.88e-03 38_[+2(2.14e-05)]_34 chr17:17743510-17743590 2.66e-03 10_[+5(9.84e-05)]_15_[+2(2.14e-05)]_\ 39 chr11:61582614-61582694 2.36e-01 80 chr16:67538380-67538460 7.98e-03 35_[+1(2.93e-05)]_37 chr12:92073839-92073919 4.13e-02 5_[+4(1.21e-05)]_67 chr4:79550633-79550713 1.38e-05 48_[+1(2.93e-05)]_4_[+3(1.09e-05)]_\ 12 chr22:38577827-38577907 1.44e-04 48_[+5(1.26e-05)]_24 chr10:16859702-16859782 1.37e-01 41_[+2(4.19e-05)]_31 chr9:140188840-140188920 1.67e-02 49_[+5(9.84e-05)]_23 chr10:102133167-10213324 2.15e-02 55_[+5(1.26e-05)]_17 chrX:155231392-155231472 2.92e-02 27_[+2(2.14e-05)]_45 chr8:11660053-11660133 1.88e-04 4_[+1(9.06e-05)]_51_[+5(1.26e-05)]_\ 9 chr3:177011411-177011491 3.91e-03 80 chr8:142726268-142726348 6.95e-01 80 chr5:90676780-90676860 6.61e-01 80 chr17:35716145-35716225 9.36e-03 1_[+2(6.91e-05)]_71 chr5:139554675-139554755 7.46e-02 80 chrX:15511484-15511564 9.73e-02 80 chr4:111115102-111115182 4.49e-02 80 chr13:46756384-46756464 2.74e-02 68_[+1(5.35e-05)]_4 chr9:128845120-128845200 1.10e-01 80 chr19:50268805-50268885 4.86e-01 80 chr17:76313748-76313828 6.70e-02 80 chr22:42228923-42229003 1.21e-03 52_[+1(2.93e-05)]_20 chr6:126279159-126279239 8.13e-02 80 chr10:104209461-10420954 4.65e-02 80 chr3:156806468-156806548 3.20e-02 80 chr22:23270885-23270965 3.56e-01 80 chr16:639820-639900 9.44e-02 33_[+5(9.84e-05)]_39 chr12:125346187-12534626 4.17e-02 80 chr11:86748919-86748999 4.80e-01 80 chr4:6675002-6675082 1.33e-01 68_[+5(3.40e-05)]_4 chr3:197466531-197466611 9.25e-02 80 chr6:26222943-26223023 5.96e-04 54_[+1(2.93e-05)]_18 chr1:76250686-76250766 7.61e-01 80 chr1:1935261-1935341 8.78e-01 80 chrX:48538991-48539071 3.28e-02 55_[+1(2.93e-05)]_17 chr7:127739413-127739493 5.09e-04 [+4(2.37e-05)]_72 chr12:1800084-1800164 3.63e-01 80 chr2:159926349-159926429 2.29e-02 3_[+4(1.21e-05)]_69 chr8:22927818-22927898 3.67e-01 80 chr12:100596541-10059662 4.34e-03 46_[+1(9.06e-05)]_26 chr1:246151935-246152015 3.28e-03 32_[+5(4.18e-05)]_40 chr19:47730400-47730480 8.55e-02 80 chr22:23499048-23499128 8.64e-01 80 chr2:209130811-209130891 1.86e-02 64_[+3(6.52e-05)]_8 chr2:201677247-201677327 5.58e-01 80 chr18:21166830-21166910 5.79e-02 14_[+1(5.35e-05)]_58 chr8:126010526-126010606 7.14e-01 80 chr11:17229585-17229665 1.28e-01 53_[+2(4.19e-05)]_19 chr9:124133557-124133637 6.61e-01 80 chr10:14420676-14420756 4.15e-05 24_[+3(2.78e-05)]_12_[+2(8.30e-05)]_\ 11_[+3(1.09e-05)]_9 chr17:61920486-61920566 3.49e-01 80 chr6:15569694-15569774 6.38e-01 80 chr11:64334206-64334286 9.84e-03 80 chr11:73490587-73490667 1.68e-02 80 chr6:53224237-53224317 3.65e-04 16_[+1(2.93e-05)]_20_[+5(3.40e-05)]_\ 28 chr8:38644572-38644652 9.90e-01 80 chr14:106267648-10626772 6.21e-01 80 chr7:26904415-26904495 6.37e-02 26_[+1(5.35e-05)]_7_[+1(5.35e-05)]_\ 31 chr2:20386395-20386475 8.15e-05 24_[+4(3.98e-05)]_12_[+4(1.21e-05)]_\ 28 chr2:223725645-223725725 6.60e-02 32_[+5(9.84e-05)]_40 chr9:114828317-114828397 5.72e-02 80 chr3:128268275-128268355 8.74e-01 80 chr6:43905221-43905301 1.34e-03 54_[+1(5.35e-05)]_18 chr1:167729442-167729522 1.08e-05 54_[+2(5.52e-05)]_7_[+4(1.21e-05)]_\ 3 chr19:49141643-49141723 6.61e-01 80 chr17:45266903-45266983 1.07e-01 35_[+2(4.19e-05)]_37 chr19:42806765-42806845 4.03e-01 80 chr10:124671558-12467163 9.10e-01 80 chr1:1677859-1677939 9.20e-01 80 chr19:49649561-49649641 7.48e-01 80 chr7:155089390-155089470 1.08e-01 80 chr22:23623566-23623646 1.77e-01 80 chr19:6737323-6737403 7.40e-01 80 chr9:130538769-130538849 6.88e-01 80 chr22:21993807-21993887 3.90e-01 80 chr19:18392674-18392754 1.41e-01 55_[+2(4.19e-05)]_17 chr19:11675739-11675819 1.80e-02 63_[+4(1.21e-05)]_9 chr9:35489953-35490033 4.98e-01 80 chr8:26434943-26435023 9.20e-03 59_[+1(2.93e-05)]_13 chr19:9929790-9929870 7.72e-02 49_[+2(2.14e-05)]_23 chr19:11308606-11308686 1.44e-01 52_[+2(4.19e-05)]_20 chr1:156163564-156163644 1.65e-01 80 chrX:48755458-48755538 3.23e-01 80 chr17:36956238-36956318 5.19e-01 80 chr16:4511456-4511536 1.58e-01 80 chr20:25604627-25604707 3.17e-01 80 chr15:90727378-90727458 1.34e-02 56_[+1(1.16e-05)]_16 chrX:48754523-48754603 7.53e-01 80 chr11:125933004-12593308 3.99e-01 80 chr5:110848381-110848461 9.72e-02 80 chr17:46133200-46133280 2.44e-02 80 chr17:80056173-80056253 3.57e-02 27_[+5(2.58e-05)]_45 chr19:50354308-50354388 9.87e-01 80 chr11:61602206-61602286 1.12e-04 27_[+2(5.52e-05)]_10_[+5(5.04e-05)]_\ 27 chr14:62162033-62162113 1.29e-02 80 chr16:88627281-88627361 1.95e-02 68_[+1(2.93e-05)]_4 chr17:7589713-7589793 1.99e-01 80 chr19:11200031-11200111 1.65e-04 15_[+2(6.91e-05)]_13_[+1(2.93e-05)]_\ 36 chrX:40506778-40506858 9.94e-01 80 chr1:1624580-1624660 9.28e-01 80 chr2:183814421-183814501 5.14e-04 [+2(6.91e-05)]_72 chr19:7627835-7627915 5.69e-01 80 chr11:6502690-6502770 1.57e-01 49_[+2(4.19e-05)]_23 chr3:119395922-119396002 6.62e-01 80 chr22:19167304-19167384 9.29e-02 19_[+2(8.30e-05)]_53 chr17:55417953-55418033 2.64e-01 80 chrX:153140943-153141023 9.10e-01 80 chr6:42518156-42518236 1.66e-02 59_[+1(2.93e-05)]_13 chr20:49923463-49923543 5.27e-01 80 chrX:70585886-70585966 4.34e-01 80 chr10:70883888-70883968 1.66e-01 80 chr11:71814440-71814520 9.33e-02 80 chrX:24247656-24247736 2.97e-03 34_[+2(4.19e-05)]_7_[+4(3.98e-05)]_\ 23 chr12:122681655-12268173 2.96e-01 80 chr3:165635819-165635899 2.31e-01 80 chr22:21995891-21995971 1.90e-01 80 chr2:20298078-20298158 5.08e-01 80 chr1:236162935-236163015 4.52e-03 64_[+2(2.14e-05)]_8 chrX:153656930-153657010 2.56e-03 17_[+5(9.84e-05)]_33_[+1(5.35e-05)]_\ 14 chr1:100828597-100828677 1.73e-04 53_[+1(2.93e-05)]_4_[+3(6.86e-05)]_\ 7 chr12:108511329-10851140 2.08e-05 9_[+2(6.91e-05)]_33_[+2(2.14e-05)]_\ 11_[+3(1.09e-05)]_3 chr22:23035442-23035522 6.22e-01 80 chr4:10175128-10175208 3.52e-02 80 chr3:43663733-43663813 7.56e-01 80 chr3:185422268-185422348 5.88e-06 26_[+2(4.19e-05)]_7_[+4(1.21e-05)]_\ 31 chr20:35012561-35012641 1.99e-01 80 chr7:154794913-154794993 9.27e-01 80 chr6:160114505-160114585 9.64e-01 80 chr19:50179858-50179938 6.95e-01 80 chr6:76055257-76055337 9.83e-04 36_[+3(3.16e-05)]_4_[+2(2.14e-05)]_\ 24 chr10:1094908-1094988 1.87e-01 80 chr22:19803083-19803163 5.48e-01 80 chr11:82612593-82612673 8.61e-01 80 chr6:15901735-15901815 3.69e-02 24_[+1(5.35e-05)]_3_[+1(5.35e-05)]_\ 37 chr5:43313757-43313837 5.08e-04 8_[+2(5.52e-05)]_5_[+2(9.63e-05)]_\ 20_[+5(2.58e-05)]_23 chr1:38230105-38230185 8.54e-01 80 chr9:14400814-14400894 1.05e-02 32_[+2(2.14e-05)]_40 chr3:46951110-46951190 5.69e-02 6_[+2(2.14e-05)]_66 chr16:71501842-71501922 7.02e-01 80 chr22:22711756-22711836 7.44e-03 18_[+1(5.35e-05)]_54 chrX:47479321-47479401 9.73e-01 80 chr21:44394199-44394279 8.32e-01 80 chr1:35318401-35318481 3.59e-03 21_[+1(5.35e-05)]_38_[+4(5.25e-05)]_\ 5 chr7:43909108-43909188 8.79e-01 80 chr9:126872734-126872814 9.79e-01 80 chr6:43878534-43878614 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1_[+2(8.30e-05)]_71 chr9:88552500-88552580 2.06e-05 8_[+2(4.19e-05)]_7_[+4(1.21e-05)]_\ 49 chr16:14580886-14580966 5.98e-02 80 chr15:48653200-48653280 2.81e-03 80 chr16:68113575-68113655 2.83e-02 80 chr9:130922148-130922228 1.07e-02 2_[+1(2.93e-05)]_70 chr1:32253919-32253999 2.05e-02 7_[+2(2.14e-05)]_65 chr15:68171191-68171271 2.04e-05 64_[+3(5.58e-06)]_8 chr7:150076242-150076322 3.26e-02 80 -------------------------------------------------------------------------------- ******************************************************************************** ******************************************************************************** Stopped because requested number of motifs (5) found. ******************************************************************************** CPU: c17n09.farnam.hpc.yale.internal ********************************************************************************