******************************************************************************** MEME - Motif discovery tool ******************************************************************************** MEME version 5.3.3 (Release date: Sun Feb 7 15:39:52 2021 -0800) For further information on how to interpret these results please access https://meme-suite.org/meme. To get a copy of the MEME Suite software please access https://meme-suite.org. ******************************************************************************** ******************************************************************************** REFERENCE ******************************************************************************** If you use this program in your research, please cite: Timothy L. Bailey and Charles Elkan, "Fitting a mixture model by expectation maximization to discover motifs in biopolymers", Proceedings of the Second International Conference on Intelligent Systems for Molecular Biology, pp. 28-36, AAAI Press, Menlo Park, California, 1994. ******************************************************************************** ******************************************************************************** TRAINING SET ******************************************************************************** PRIMARY SEQUENCES= ../result/final_prediction/K562/fasta/RankLinear0.6_40/SNRNP70.fasta CONTROL SEQUENCES= --none-- ALPHABET= ACGT Sequence name Weight Length Sequence name Weight Length ------------- ------ ------ ------------- ------ ------ chr19:49991343-49991423 1.0000 80 chr3:39457591-39457671 1.0000 80 chr19:42377183-42377263 1.0000 80 chr19:8388840-8388920 1.0000 80 chr19:13050085-13050165 1.0000 80 chr22:21221017-21221097 1.0000 80 chr22:21408382-21408462 1.0000 80 chr8:146016805-146016885 1.0000 80 chr22:19678051-19678131 1.0000 80 chr19:55902519-55902599 1.0000 80 chr22:20082061-20082141 1.0000 80 chr1:109941153-109941233 1.0000 80 chr12:6977571-6977651 1.0000 80 chr22:20809553-20809633 1.0000 80 chr1:207195557-207195637 1.0000 80 chr5:177639832-177639912 1.0000 80 chr22:21126597-21126677 1.0000 80 chr19:8387650-8387730 1.0000 80 chr22:19821045-19821125 1.0000 80 chr9:140507757-140507837 1.0000 80 chr5:177633450-177633530 1.0000 80 chr8:146015924-146016004 1.0000 80 chr16:89807970-89808050 1.0000 80 chr16:2014122-2014202 1.0000 80 chr21:44257129-44257209 1.0000 80 chr17:25418288-25418368 1.0000 80 chr17:25409867-25409947 1.0000 80 chr22:19175065-19175145 1.0000 80 chr6:30688706-30688786 1.0000 80 chr9:138841556-138841636 1.0000 80 chr22:20175132-20175212 1.0000 80 chr22:21304372-21304452 1.0000 80 chr22:22445949-22446029 1.0000 80 chr22:19356573-19356653 1.0000 80 chr22:19363153-19363233 1.0000 80 chr4:174254657-174254737 1.0000 80 chr22:20086775-20086855 1.0000 80 chr13:90939943-90940023 1.0000 80 chr9:139618657-139618737 1.0000 80 chr19:39126000-39126080 1.0000 80 chr12:57118529-57118609 1.0000 80 chr11:65191446-65191526 1.0000 80 chr22:23274667-23274747 1.0000 80 chr6:7116064-7116144 1.0000 80 chr19:10227023-10227103 1.0000 80 chr1:35859995-35860075 1.0000 80 chr11:813720-813800 1.0000 80 chr7:105494536-105494616 1.0000 80 chr7:153102246-153102326 1.0000 80 chr22:19453737-19453817 1.0000 80 chr19:42364776-42364856 1.0000 80 chr19:49993889-49993969 1.0000 80 chr22:22936381-22936461 1.0000 80 chr22:19445495-19445575 1.0000 80 chr22:20989276-20989356 1.0000 80 chr6:31752453-31752533 1.0000 80 chr1:156461935-156462015 1.0000 80 chr11:63993022-63993102 1.0000 80 chr22:19444217-19444297 1.0000 80 chr3:39456091-39456171 1.0000 80 chr9:139620800-139620880 1.0000 80 chr9:131591454-131591534 1.0000 80 chr22:22025158-22025238 1.0000 80 chr17:80561956-80562036 1.0000 80 chr22:22068421-22068501 1.0000 80 chr2:219271703-219271783 1.0000 80 chr3:47879425-47879505 1.0000 80 chr1:45986982-45987062 1.0000 80 chr22:20821140-20821220 1.0000 80 chr5:862094-862174 1.0000 80 chr13:90685529-90685609 1.0000 80 chr7:139666858-139666938 1.0000 80 chr16:67244749-67244829 1.0000 80 chr22:20116467-20116547 1.0000 80 chr22:20870755-20870835 1.0000 80 chr9:139565092-139565172 1.0000 80 chr22:22477893-22477973 1.0000 80 chr10:76992134-76992214 1.0000 80 chr22:39715092-39715172 1.0000 80 chr12:54677007-54677087 1.0000 80 chr16:2204922-2205002 1.0000 80 chr6:27095044-27095124 1.0000 80 chr22:23052761-23052841 1.0000 80 chr17:80015008-80015088 1.0000 80 chr3:39455400-39455480 1.0000 80 chr13:91834542-91834622 1.0000 80 chr22:19946162-19946242 1.0000 80 chr19:799502-799582 1.0000 80 chr11:5264695-5264775 1.0000 80 chr7:25164289-25164369 1.0000 80 chr11:62434111-62434191 1.0000 80 chr5:177633672-177633752 1.0000 80 chr22:21083213-21083293 1.0000 80 chr17:56404988-56405068 1.0000 80 chr15:69749102-69749182 1.0000 80 chr22:21229734-21229814 1.0000 80 chr21:44254084-44254164 1.0000 80 chr1:28833897-28833977 1.0000 80 chr19:10226055-10226135 1.0000 80 chr3:15105939-15106019 1.0000 80 chr22:22093486-22093566 1.0000 80 chr22:20240819-20240899 1.0000 80 chr2:91800570-91800650 1.0000 80 chr12:123465744-12346582 1.0000 80 chr22:19942113-19942193 1.0000 80 chr22:19437004-19437084 1.0000 80 chr22:23034134-23034214 1.0000 80 chr6:16130251-16130331 1.0000 80 chr22:21922833-21922913 1.0000 80 chr9:139620046-139620126 1.0000 80 chr1:23856422-23856502 1.0000 80 chr5:81570753-81570833 1.0000 80 chr22:21187600-21187680 1.0000 80 chr2:85767198-85767278 1.0000 80 chr6:26131278-26131358 1.0000 80 chr22:21953660-21953740 1.0000 80 chr10:47056575-47056655 1.0000 80 chr12:120638477-12063855 1.0000 80 chr17:73771239-73771319 1.0000 80 chr19:8389908-8389988 1.0000 80 chr1:76262819-76262899 1.0000 80 chr20:57195143-57195223 1.0000 80 chr11:93474126-93474206 1.0000 80 chr1:28833080-28833160 1.0000 80 chr16:88877344-88877424 1.0000 80 chr22:23250544-23250624 1.0000 80 chr22:22554209-22554289 1.0000 80 chr22:19410319-19410399 1.0000 80 chr1:180133542-180133622 1.0000 80 chr6:133136216-133136296 1.0000 80 chr16:2203035-2203115 1.0000 80 chr19:54715121-54715201 1.0000 80 chr1:1335496-1335576 1.0000 80 chr9:136024102-136024182 1.0000 80 chr5:137805862-137805942 1.0000 80 chr22:19394251-19394331 1.0000 80 chr1:228296453-228296533 1.0000 80 chr19:8389708-8389788 1.0000 80 chr22:22555930-22556010 1.0000 80 chr9:136027090-136027170 1.0000 80 chr10:71094768-71094848 1.0000 80 chr3:195435110-195435190 1.0000 80 chr5:137802556-137802636 1.0000 80 chr19:12896900-12896980 1.0000 80 chr22:19074071-19074151 1.0000 80 chr20:31219746-31219826 1.0000 80 chr12:123848527-12384860 1.0000 80 chr6:74230004-74230084 1.0000 80 chr19:54713647-54713727 1.0000 80 chr17:79479198-79479278 1.0000 80 chr2:10266050-10266130 1.0000 80 chr19:49470646-49470726 1.0000 80 chr9:132623294-132623374 1.0000 80 chr11:65192895-65192975 1.0000 80 chr22:19752945-19753025 1.0000 80 chr22:19951547-19951627 1.0000 80 chr16:89632473-89632553 1.0000 80 chr17:56409484-56409564 1.0000 80 chr22:20884784-20884864 1.0000 80 chr22:22043442-22043522 1.0000 80 chr22:22531414-22531494 1.0000 80 chr17:56408715-56408795 1.0000 80 chr22:23034790-23034870 1.0000 80 chr22:21011003-21011083 1.0000 80 chr6:37143953-37144033 1.0000 80 chr21:44251081-44251161 1.0000 80 chr22:19862364-19862444 1.0000 80 chr22:21805987-21806067 1.0000 80 chr1:149857319-149857399 1.0000 80 chr3:14180920-14181000 1.0000 80 chr8:145096390-145096470 1.0000 80 chr16:2012276-2012356 1.0000 80 chr22:19184714-19184794 1.0000 80 chr1:173836702-173836782 1.0000 80 chr22:22322207-22322287 1.0000 80 chr20:62329302-62329382 1.0000 80 chr19:6412704-6412784 1.0000 80 chr17:56408015-56408095 1.0000 80 chr5:40825817-40825897 1.0000 80 chr7:153100357-153100437 1.0000 80 chr19:586060-586140 1.0000 80 chr22:19928665-19928745 1.0000 80 chr6:44222479-44222559 1.0000 80 chr1:28836525-28836605 1.0000 80 chr13:92067476-92067556 1.0000 80 chr22:19943181-19943261 1.0000 80 chr7:158695541-158695621 1.0000 80 chr6:33240158-33240238 1.0000 80 chr6:119558581-119558661 1.0000 80 chr17:79859328-79859408 1.0000 80 chr7:5568234-5568314 1.0000 80 chr22:20961332-20961412 1.0000 80 chr11:65191648-65191728 1.0000 80 chr6:30583993-30584073 1.0000 80 chr19:49117713-49117793 1.0000 80 chr2:88315636-88315716 1.0000 80 chr19:10945821-10945901 1.0000 80 chr19:10223136-10223216 1.0000 80 chr5:179050097-179050177 1.0000 80 chr4:119200104-119200184 1.0000 80 chr17:16284686-16284766 1.0000 80 chr1:227915252-227915332 1.0000 80 chr6:26026626-26026706 1.0000 80 chr22:23398112-23398192 1.0000 80 chr7:102112604-102112684 1.0000 80 chr1:27985486-27985566 1.0000 80 chr1:144008584-144008664 1.0000 80 chr1:3696167-3696247 1.0000 80 chr12:125398771-12539885 1.0000 80 chr19:1394875-1394955 1.0000 80 chr9:139566122-139566202 1.0000 80 chr5:170815403-170815483 1.0000 80 chr6:34214338-34214418 1.0000 80 chr16:2288416-2288496 1.0000 80 chr22:23160707-23160787 1.0000 80 chr6:26056287-26056367 1.0000 80 chr22:19948539-19948619 1.0000 80 chr6:44223152-44223232 1.0000 80 chr7:150754466-150754546 1.0000 80 chr6:33245333-33245413 1.0000 80 chr22:23535958-23536038 1.0000 80 chr11:93474337-93474417 1.0000 80 chr22:19506539-19506619 1.0000 80 chr11:62433091-62433171 1.0000 80 chr22:22037850-22037930 1.0000 80 chr22:20969818-20969898 1.0000 80 chr11:118963953-11896403 1.0000 80 chr6:27101707-27101787 1.0000 80 chr6:86388191-86388271 1.0000 80 chr6:26216656-26216736 1.0000 80 chr1:3816153-3816233 1.0000 80 chr16:81514481-81514561 1.0000 80 chr17:56405954-56406034 1.0000 80 chr17:73775036-73775116 1.0000 80 chr22:20928862-20928942 1.0000 80 chr11:62623043-62623123 1.0000 80 chr11:65268089-65268169 1.0000 80 chr6:26027288-26027368 1.0000 80 chr22:20891683-20891763 1.0000 80 chr2:91820506-91820586 1.0000 80 chr22:20116994-20117074 1.0000 80 chr22:20861278-20861358 1.0000 80 chr1:1335264-1335344 1.0000 80 chr20:47895330-47895410 1.0000 80 chr3:39485251-39485331 1.0000 80 chr6:158161566-158161646 1.0000 80 chr22:22321058-22321138 1.0000 80 chr6:26204968-26205048 1.0000 80 chr6:27115077-27115157 1.0000 80 chr6:26124550-26124630 1.0000 80 ******************************************************************************** ******************************************************************************** COMMAND LINE SUMMARY ******************************************************************************** This information can also be useful in the event you wish to report a problem with the MEME software. command: meme -oc ../result/final_prediction/K562/inference_raw/MEME/RankLinear0.6_40_SNRNP70/ -dna -nmotifs 5 -w 8 -maxsize 250000 -nostatus ../result/final_prediction/K562/fasta/RankLinear0.6_40/SNRNP70.fasta model: mod= zoops nmotifs= 5 evt= inf objective function: em= E-value of product of p-values starts= E-value of product of p-values strands: + width: minw= 8 maxw= 8 nsites: minsites= 2 maxsites= 250 wnsites= 0.8 theta: spmap= uni spfuzz= 0.5 em: prior= dirichlet b= 0.01 maxiter= 50 distance= 1e-05 trim: wg= 11 ws= 1 endgaps= yes data: n= 20000 N= 250 sample: seed= 0 hsfrac= 0 searchsize= 20000 norand= no csites= 1000 Letter frequencies in dataset: A 0.211 C 0.292 G 0.287 T 0.209 Background letter frequencies (from file dataset with add-one prior applied): A 0.211 C 0.292 G 0.287 T 0.209 Background model order: 0 ******************************************************************************** ******************************************************************************** MOTIF AGGGCAGR MEME-1 width = 8 sites = 32 llr = 265 E-value = 1.0e+002 ******************************************************************************** -------------------------------------------------------------------------------- Motif AGGGCAGR MEME-1 Description -------------------------------------------------------------------------------- Simplified A 7:2:2a:4 pos.-specific C ::::8::: probability G :a8a::a5 matrix T 3::::::1 bits 2.3 * 2.0 * 1.8 * * ** 1.6 * * ** Relative 1.4 ** * ** Entropy 1.1 ******* (11.9 bits) 0.9 ******* 0.7 ******** 0.5 ******** 0.2 ******** 0.0 -------- Multilevel AGGGCAGG consensus T A A A sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AGGGCAGR MEME-1 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr6:34214338-34214418 51 4.39e-05 ACACCCACAA AGGGCAGA AGGCCTGGGG chr19:10945821-10945901 63 4.39e-05 CCGCCTGGGA AGGGCAGG GCTGTAACTG chr22:19943181-19943261 45 4.39e-05 cagccctgtg agggcagg ATGAGGCACG chr3:14180920-14181000 61 4.39e-05 GGCAGGCTTG AGGGCAGG AGCTGCCAGG chr20:31219746-31219826 71 4.39e-05 TCCTTGAGGC AGGGCAGG AC chr16:2203035-2203115 19 4.39e-05 AAGGTGAGTC AGGGCAGG GGGGTGGTGA chr22:23250544-23250624 51 4.39e-05 AGAGCCTGCA AGGGCAGA GAACTCTAGG chr22:19437004-19437084 4 4.39e-05 ACC AGGGCAGG ACCCCCATGT chr22:19363153-19363233 31 4.39e-05 CATGCTGGTC AGGGCAGG AGCACCTGGT chr21:44257129-44257209 24 4.39e-05 GTGCATCTTC AGGGCAGA CTCCACCAAG chr6:33240158-33240238 4 8.74e-05 GAA TGGGCAGG AGACCTGCTT chr22:22322207-22322287 29 8.74e-05 CCTGTTCAGG TGGGCAGA TACGCAAGCT chr17:56404988-56405068 38 8.74e-05 TGGCCCAGGC TGGGCAGA CAAGCCTCTG chr22:22068421-22068501 63 8.74e-05 AAGATGTGTG TGGGCAGA ACGCAGCGTT chr5:177633450-177633530 49 8.74e-05 TGGGACTGCT TGGGCAGG AAGAGCATGA chr22:21126597-21126677 1 8.74e-05 . tgggcaga aagaatagca chr22:19948539-19948619 63 1.51e-04 TCGCCCTGCT AGGGAAGG CTCAGGCCAG chr6:30583993-30584073 56 1.51e-04 GCAGCAAGGC AGGGAAGA GATAGGTGGT chr22:20884784-20884864 56 1.51e-04 CAGTTGGACC AGGGAAGG GGGCCTGGCA chr22:19394251-19394331 24 1.51e-04 TTTTGAGAGT AGAGCAGA GGCTGCCCCA chr6:133136216-133136296 70 1.51e-04 CTGCCACCCA AGGGAAGA AGG chr12:120638477-12063855 27 1.51e-04 GGCAACATGA AGAGCAGA GGCGACCCAC chr1:23856422-23856502 68 1.51e-04 GCTGTCTGGG AGGGAAGA CTGGG chr12:123465744-12346582 22 1.51e-04 AGAAAGAAGA AGAGCAGG AAAGACACCT chr22:22321058-22321138 63 1.70e-04 TAGGCTGGTC AGGGCAGT GCCTTCTGCA chr22:19074071-19074151 29 1.70e-04 GAGCCTTGTC AGGGCAGT GGCCTCCTCA chr9:139618657-139618737 36 1.70e-04 TGAAGCCGCC AGGGCAGT TCCCCAAACA chr6:44222479-44222559 41 2.33e-04 GCGTAGACTC TGAGCAGG AGGGCAGCAA chr7:139666858-139666938 56 2.33e-04 TGGGGAAtct tgagcagg ataccagcta chr22:23274667-23274747 26 2.33e-04 AGTAAGGGGA TGGGAAGG GAAACAAGAA chr9:138841556-138841636 69 2.33e-04 CTGCACAGCA TGAGCAGG ACAC chr13:92067476-92067556 4 2.57e-04 taa agagaagg attgcttagg -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AGGGCAGR MEME-1 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr6:34214338-34214418 4.4e-05 50_[+1]_22 chr19:10945821-10945901 4.4e-05 62_[+1]_10 chr22:19943181-19943261 4.4e-05 44_[+1]_28 chr3:14180920-14181000 4.4e-05 60_[+1]_12 chr20:31219746-31219826 4.4e-05 70_[+1]_2 chr16:2203035-2203115 4.4e-05 18_[+1]_54 chr22:23250544-23250624 4.4e-05 50_[+1]_22 chr22:19437004-19437084 4.4e-05 3_[+1]_69 chr22:19363153-19363233 4.4e-05 30_[+1]_42 chr21:44257129-44257209 4.4e-05 23_[+1]_49 chr6:33240158-33240238 8.7e-05 3_[+1]_69 chr22:22322207-22322287 8.7e-05 28_[+1]_44 chr17:56404988-56405068 8.7e-05 37_[+1]_35 chr22:22068421-22068501 8.7e-05 62_[+1]_10 chr5:177633450-177633530 8.7e-05 48_[+1]_24 chr22:21126597-21126677 8.7e-05 [+1]_72 chr22:19948539-19948619 0.00015 62_[+1]_10 chr6:30583993-30584073 0.00015 55_[+1]_17 chr22:20884784-20884864 0.00015 55_[+1]_17 chr22:19394251-19394331 0.00015 23_[+1]_49 chr6:133136216-133136296 0.00015 69_[+1]_3 chr12:120638477-12063855 0.00015 26_[+1]_46 chr1:23856422-23856502 0.00015 67_[+1]_5 chr12:123465744-12346582 0.00015 21_[+1]_51 chr22:22321058-22321138 0.00017 62_[+1]_10 chr22:19074071-19074151 0.00017 28_[+1]_44 chr9:139618657-139618737 0.00017 35_[+1]_37 chr6:44222479-44222559 0.00023 40_[+1]_32 chr7:139666858-139666938 0.00023 55_[+1]_17 chr22:23274667-23274747 0.00023 25_[+1]_47 chr9:138841556-138841636 0.00023 68_[+1]_4 chr13:92067476-92067556 0.00026 3_[+1]_69 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AGGGCAGR MEME-1 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF AGGGCAGR width=8 seqs=32 chr6:34214338-34214418 ( 51) AGGGCAGA 1 chr19:10945821-10945901 ( 63) AGGGCAGG 1 chr22:19943181-19943261 ( 45) AGGGCAGG 1 chr3:14180920-14181000 ( 61) AGGGCAGG 1 chr20:31219746-31219826 ( 71) AGGGCAGG 1 chr16:2203035-2203115 ( 19) AGGGCAGG 1 chr22:23250544-23250624 ( 51) AGGGCAGA 1 chr22:19437004-19437084 ( 4) AGGGCAGG 1 chr22:19363153-19363233 ( 31) AGGGCAGG 1 chr21:44257129-44257209 ( 24) AGGGCAGA 1 chr6:33240158-33240238 ( 4) TGGGCAGG 1 chr22:22322207-22322287 ( 29) TGGGCAGA 1 chr17:56404988-56405068 ( 38) TGGGCAGA 1 chr22:22068421-22068501 ( 63) TGGGCAGA 1 chr5:177633450-177633530 ( 49) TGGGCAGG 1 chr22:21126597-21126677 ( 1) TGGGCAGA 1 chr22:19948539-19948619 ( 63) AGGGAAGG 1 chr6:30583993-30584073 ( 56) AGGGAAGA 1 chr22:20884784-20884864 ( 56) AGGGAAGG 1 chr22:19394251-19394331 ( 24) AGAGCAGA 1 chr6:133136216-133136296 ( 70) AGGGAAGA 1 chr12:120638477-12063855 ( 27) AGAGCAGA 1 chr1:23856422-23856502 ( 68) AGGGAAGA 1 chr12:123465744-12346582 ( 22) AGAGCAGG 1 chr22:22321058-22321138 ( 63) AGGGCAGT 1 chr22:19074071-19074151 ( 29) AGGGCAGT 1 chr9:139618657-139618737 ( 36) AGGGCAGT 1 chr6:44222479-44222559 ( 41) TGAGCAGG 1 chr7:139666858-139666938 ( 56) TGAGCAGG 1 chr22:23274667-23274747 ( 26) TGGGAAGG 1 chr9:138841556-138841636 ( 69) TGAGCAGG 1 chr13:92067476-92067556 ( 4) AGAGAAGG 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AGGGCAGR MEME-1 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 9.15308 E= 1.0e+002 170 -1164 -1164 58 -1164 -1164 180 -1164 5 -1164 144 -1164 -1164 -1164 180 -1164 5 142 -1164 -1164 224 -1164 -1164 -1164 -1164 -1164 180 -1164 83 -1164 89 -116 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AGGGCAGR MEME-1 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 32 E= 1.0e+002 0.687500 0.000000 0.000000 0.312500 0.000000 0.000000 1.000000 0.000000 0.218750 0.000000 0.781250 0.000000 0.000000 0.000000 1.000000 0.000000 0.218750 0.781250 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.375000 0.000000 0.531250 0.093750 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AGGGCAGR MEME-1 regular expression -------------------------------------------------------------------------------- [AT]G[GA]G[CA]AG[GA] -------------------------------------------------------------------------------- Time 5.22 secs. ******************************************************************************** ******************************************************************************** MOTIF CTGTCCTG MEME-2 width = 8 sites = 8 llr = 87 E-value = 3.0e+002 ******************************************************************************** -------------------------------------------------------------------------------- Motif CTGTCCTG MEME-2 Description -------------------------------------------------------------------------------- Simplified A :::::::: pos.-specific C a:::aa:: probability G ::a::::a matrix T :a:a::a: bits 2.3 * * * 2.0 * * * 1.8 ******** 1.6 ******** Relative 1.4 ******** Entropy 1.1 ******** (15.7 bits) 0.9 ******** 0.7 ******** 0.5 ******** 0.2 ******** 0.0 -------- Multilevel CTGTCCTG consensus sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTGTCCTG MEME-2 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr3:39485251-39485331 34 1.87e-05 GTGAGCACCT CTGTCCTG GGCACTGGGT chr22:22037850-22037930 1 1.87e-05 . CTGTCCTG CAGCCTTGGA chr17:79859328-79859408 57 1.87e-05 GTGCCAGTGC CTGTCCTG GGAAGATACC chr22:19928665-19928745 41 1.87e-05 GAGGCTTGAA CTGTCCTG AGTGACCAGA chr22:20884784-20884864 6 1.87e-05 GCTGG CTGTCCTG GGAATTCATG chr1:76262819-76262899 7 1.87e-05 ATCCAC CTGTCCTG GCACGTCAGG chr11:813720-813800 14 1.87e-05 CCGACAGGCT CTGTCCTG GAATACAGGG chr6:7116064-7116144 71 1.87e-05 TGACGTATGT CTGTCCTG CC -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTGTCCTG MEME-2 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr3:39485251-39485331 1.9e-05 33_[+2]_39 chr22:22037850-22037930 1.9e-05 [+2]_72 chr17:79859328-79859408 1.9e-05 56_[+2]_16 chr22:19928665-19928745 1.9e-05 40_[+2]_32 chr22:20884784-20884864 1.9e-05 5_[+2]_67 chr1:76262819-76262899 1.9e-05 6_[+2]_66 chr11:813720-813800 1.9e-05 13_[+2]_59 chr6:7116064-7116144 1.9e-05 70_[+2]_2 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTGTCCTG MEME-2 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF CTGTCCTG width=8 seqs=8 chr3:39485251-39485331 ( 34) CTGTCCTG 1 chr22:22037850-22037930 ( 1) CTGTCCTG 1 chr17:79859328-79859408 ( 57) CTGTCCTG 1 chr22:19928665-19928745 ( 41) CTGTCCTG 1 chr22:20884784-20884864 ( 6) CTGTCCTG 1 chr1:76262819-76262899 ( 7) CTGTCCTG 1 chr11:813720-813800 ( 14) CTGTCCTG 1 chr6:7116064-7116144 ( 71) CTGTCCTG 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTGTCCTG MEME-2 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 11.155 E= 3.0e+002 -965 177 -965 -965 -965 -965 -965 225 -965 -965 180 -965 -965 -965 -965 225 -965 177 -965 -965 -965 177 -965 -965 -965 -965 -965 225 -965 -965 180 -965 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTGTCCTG MEME-2 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 8 E= 3.0e+002 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTGTCCTG MEME-2 regular expression -------------------------------------------------------------------------------- CTGTCCTG -------------------------------------------------------------------------------- Time 9.18 secs. ******************************************************************************** ******************************************************************************** MOTIF RGCCTSTG MEME-3 width = 8 sites = 17 llr = 160 E-value = 1.2e+002 ******************************************************************************** -------------------------------------------------------------------------------- Motif RGCCTSTG MEME-3 Description -------------------------------------------------------------------------------- Simplified A 6::::::: pos.-specific C ::aa:6:: probability G 4a:::4:a matrix T ::::a:a: bits 2.3 * * 2.0 * * 1.8 **** ** 1.6 **** ** Relative 1.4 **** ** Entropy 1.1 ***** ** (13.6 bits) 0.9 ******** 0.7 ******** 0.5 ******** 0.2 ******** 0.0 -------- Multilevel AGCCTCTG consensus G G sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif RGCCTSTG MEME-3 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr22:20891683-20891763 17 1.89e-05 TTGCAGGCCC AGCCTCTG GCCCCAGACC chr1:27985486-27985566 48 1.89e-05 ggccatacgg agcctctg aatggttttg chr22:19928665-19928745 64 1.89e-05 CCAGACACCC AGCCTCTG CTTCGAGTG chr1:28833080-28833160 56 1.89e-05 CGACCCAGCG AGCCTCTG AAGGTGCACC chr17:56404988-56405068 48 1.89e-05 TGGGCAGACA AGCCTCTG CTCCTTCAGG chr22:20086775-20086855 65 1.89e-05 ctagtgcccc agcctctg gcagctgc chr22:20082061-20082141 68 1.89e-05 GCCCTCGCTC AGCCTCTG AGCTG chr16:81514481-81514561 28 3.75e-05 GTGGGAAAGA AGCCTGTG TGTGATGTCA chr6:86388191-86388271 37 3.75e-05 CAAAACTCGG AGCCTGTG GCCGTCACGA chr21:44254084-44254164 15 3.75e-05 caaaatgtgt agcctgtg aaatgatgtc chr3:47879425-47879505 46 3.75e-05 ACCAGCAGTG AGCCTGTG GGGACGAGAT chr9:139620046-139620126 62 6.32e-05 ctgcgtcttt ggcctctG TACCCCCATT chr22:20870755-20870835 3 6.32e-05 TT GGCCTCTG CCAACCAGTA chr6:31752453-31752533 12 6.32e-05 GCCGGACAAA GGCCTCTG TCACAGCTGC chr7:153100357-153100437 23 8.85e-05 GCACTGACTG GGCCTGTG AGTTACAACC chr22:20240819-20240899 6 8.85e-05 GACCC GGCCTGTG CTCAGAGTCG chr19:42364776-42364856 35 8.85e-05 GTCTCTGCCA GGCCTGTG TTCACATGCT -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif RGCCTSTG MEME-3 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr22:20891683-20891763 1.9e-05 16_[+3]_56 chr1:27985486-27985566 1.9e-05 47_[+3]_25 chr22:19928665-19928745 1.9e-05 63_[+3]_9 chr1:28833080-28833160 1.9e-05 55_[+3]_17 chr17:56404988-56405068 1.9e-05 47_[+3]_25 chr22:20086775-20086855 1.9e-05 64_[+3]_8 chr22:20082061-20082141 1.9e-05 67_[+3]_5 chr16:81514481-81514561 3.7e-05 27_[+3]_45 chr6:86388191-86388271 3.7e-05 36_[+3]_36 chr21:44254084-44254164 3.7e-05 14_[+3]_58 chr3:47879425-47879505 3.7e-05 45_[+3]_27 chr9:139620046-139620126 6.3e-05 61_[+3]_11 chr22:20870755-20870835 6.3e-05 2_[+3]_70 chr6:31752453-31752533 6.3e-05 11_[+3]_61 chr7:153100357-153100437 8.8e-05 22_[+3]_50 chr22:20240819-20240899 8.8e-05 5_[+3]_67 chr19:42364776-42364856 8.8e-05 34_[+3]_38 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif RGCCTSTG MEME-3 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF RGCCTSTG width=8 seqs=17 chr22:20891683-20891763 ( 17) AGCCTCTG 1 chr1:27985486-27985566 ( 48) AGCCTCTG 1 chr22:19928665-19928745 ( 64) AGCCTCTG 1 chr1:28833080-28833160 ( 56) AGCCTCTG 1 chr17:56404988-56405068 ( 48) AGCCTCTG 1 chr22:20086775-20086855 ( 65) AGCCTCTG 1 chr22:20082061-20082141 ( 68) AGCCTCTG 1 chr16:81514481-81514561 ( 28) AGCCTGTG 1 chr6:86388191-86388271 ( 37) AGCCTGTG 1 chr21:44254084-44254164 ( 15) AGCCTGTG 1 chr3:47879425-47879505 ( 46) AGCCTGTG 1 chr9:139620046-139620126 ( 62) GGCCTCTG 1 chr22:20870755-20870835 ( 3) GGCCTCTG 1 chr6:31752453-31752533 ( 12) GGCCTCTG 1 chr7:153100357-153100437 ( 23) GGCCTGTG 1 chr22:20240819-20240899 ( 6) GGCCTGTG 1 chr19:42364776-42364856 ( 35) GGCCTGTG 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif RGCCTSTG MEME-3 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 10.8621 E= 1.2e+002 161 -1073 30 -1073 -1073 -1073 180 -1073 -1073 177 -1073 -1073 -1073 177 -1073 -1073 -1073 -1073 -1073 225 -1073 101 52 -1073 -1073 -1073 -1073 225 -1073 -1073 180 -1073 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif RGCCTSTG MEME-3 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 17 E= 1.2e+002 0.647059 0.000000 0.352941 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.588235 0.411765 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif RGCCTSTG MEME-3 regular expression -------------------------------------------------------------------------------- [AG]GCCT[CG]TG -------------------------------------------------------------------------------- Time 13.09 secs. ******************************************************************************** ******************************************************************************** MOTIF TTTTSYTW MEME-4 width = 8 sites = 12 llr = 120 E-value = 6.4e+002 ******************************************************************************** -------------------------------------------------------------------------------- Motif TTTTSYTW MEME-4 Description -------------------------------------------------------------------------------- Simplified A :::::::3 pos.-specific C ::::65:: probability G ::::4::: matrix T aaaa:5a7 bits 2.3 **** * 2.0 **** * 1.8 **** * 1.6 **** * Relative 1.4 **** ** Entropy 1.1 **** *** (14.4 bits) 0.9 ******** 0.7 ******** 0.5 ******** 0.2 ******** 0.0 -------- Multilevel TTTTCCTT consensus GT A sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTTTSYTW MEME-4 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr2:88315636-88315716 46 5.09e-06 gctcaagcca ttttcttt caaaaagagc chr5:40825817-40825897 1 5.09e-06 . ttttcttt ttttgagaca chr6:74230004-74230084 57 1.72e-05 GGAAAGGCCC TTTTCCTT TGTGTGGGTG chr13:91834542-91834622 6 1.72e-05 ggatc ttttgttt tttgccagca chr22:20086775-20086855 14 1.72e-05 catctccagc ttttcctt cttgggttct chr22:20082061-20082141 5 1.72e-05 GGGC TTTTCCTT CTGTCCTCTC chr22:19678051-19678131 24 1.72e-05 ccctgcttcc ttttgttt gtttgttttt chr19:8388840-8388920 5 1.72e-05 TCCT TTTTCCTT TGATAAGAGC chr22:19862364-19862444 30 2.93e-05 CTAAGTGATG TTTTCTTA AGGAAGACAC chr1:144008584-144008664 47 4.15e-05 CCCTGCCTGT TTTTGTTA AATGATCAGT chr1:3696167-3696247 60 4.86e-05 ATCCTCCAGC TTTTGCTA CCATCTGTCC chr12:6977571-6977651 70 4.86e-05 GCCCCTCTCC TTTTGCTA CAA -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTTTSYTW MEME-4 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr2:88315636-88315716 5.1e-06 45_[+4]_27 chr5:40825817-40825897 5.1e-06 [+4]_72 chr6:74230004-74230084 1.7e-05 56_[+4]_16 chr13:91834542-91834622 1.7e-05 5_[+4]_67 chr22:20086775-20086855 1.7e-05 13_[+4]_59 chr22:20082061-20082141 1.7e-05 4_[+4]_68 chr22:19678051-19678131 1.7e-05 23_[+4]_49 chr19:8388840-8388920 1.7e-05 4_[+4]_68 chr22:19862364-19862444 2.9e-05 29_[+4]_43 chr1:144008584-144008664 4.2e-05 46_[+4]_26 chr1:3696167-3696247 4.9e-05 59_[+4]_13 chr12:6977571-6977651 4.9e-05 69_[+4]_3 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTTTSYTW MEME-4 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF TTTTSYTW width=8 seqs=12 chr2:88315636-88315716 ( 46) TTTTCTTT 1 chr5:40825817-40825897 ( 1) TTTTCTTT 1 chr6:74230004-74230084 ( 57) TTTTCCTT 1 chr13:91834542-91834622 ( 6) TTTTGTTT 1 chr22:20086775-20086855 ( 14) TTTTCCTT 1 chr22:20082061-20082141 ( 5) TTTTCCTT 1 chr22:19678051-19678131 ( 24) TTTTGTTT 1 chr19:8388840-8388920 ( 5) TTTTCCTT 1 chr22:19862364-19862444 ( 30) TTTTCTTA 1 chr1:144008584-144008664 ( 47) TTTTGTTA 1 chr1:3696167-3696247 ( 60) TTTTGCTA 1 chr12:6977571-6977651 ( 70) TTTTGCTA 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTTTSYTW MEME-4 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 11.6697 E= 6.4e+002 -1023 -1023 -1023 225 -1023 -1023 -1023 225 -1023 -1023 -1023 225 -1023 -1023 -1023 225 -1023 100 54 -1023 -1023 77 -1023 125 -1023 -1023 -1023 225 66 -1023 -1023 167 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTTTSYTW MEME-4 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 12 E= 6.4e+002 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.583333 0.416667 0.000000 0.000000 0.500000 0.000000 0.500000 0.000000 0.000000 0.000000 1.000000 0.333333 0.000000 0.000000 0.666667 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTTTSYTW MEME-4 regular expression -------------------------------------------------------------------------------- TTTT[CG][CT]T[TA] -------------------------------------------------------------------------------- Time 16.96 secs. ******************************************************************************** ******************************************************************************** MOTIF TTTGTTTT MEME-5 width = 8 sites = 2 llr = 24 E-value = 1.0e+004 ******************************************************************************** -------------------------------------------------------------------------------- Motif TTTGTTTT MEME-5 Description -------------------------------------------------------------------------------- Simplified A :::::::: pos.-specific C :::::::: probability G :::a:::: matrix T aaa:aaaa bits 2.3 *** **** 2.0 *** **** 1.8 ******** 1.6 ******** Relative 1.4 ******** Entropy 1.1 ******** (17.6 bits) 0.9 ******** 0.7 ******** 0.5 ******** 0.2 ******** 0.0 -------- Multilevel TTTGTTTT consensus sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTTGTTTT MEME-5 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr22:19678051-19678131 33 5.00e-06 cttttgtttg tttgtttt tgtttctttg chr22:21221017-21221097 33 5.00e-06 TTCGTTGTGA TTTGTTTT TAGGAAAACT -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTTGTTTT MEME-5 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr22:19678051-19678131 5e-06 32_[+5]_40 chr22:21221017-21221097 5e-06 32_[+5]_40 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTTGTTTT MEME-5 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF TTTGTTTT width=8 seqs=2 chr22:19678051-19678131 ( 33) TTTGTTTT 1 chr22:21221017-21221097 ( 33) TTTGTTTT 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTTGTTTT MEME-5 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 13.1555 E= 1.0e+004 -765 -765 -765 225 -765 -765 -765 225 -765 -765 -765 225 -765 -765 180 -765 -765 -765 -765 225 -765 -765 -765 225 -765 -765 -765 225 -765 -765 -765 225 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTTGTTTT MEME-5 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 2 E= 1.0e+004 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTTGTTTT MEME-5 regular expression -------------------------------------------------------------------------------- TTTGTTTT -------------------------------------------------------------------------------- Time 20.71 secs. ******************************************************************************** ******************************************************************************** SUMMARY OF MOTIFS ******************************************************************************** -------------------------------------------------------------------------------- Combined block diagrams: non-overlapping sites with p-value < 0.0001 -------------------------------------------------------------------------------- SEQUENCE NAME COMBINED P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr19:49991343-49991423 1.10e-01 80 chr3:39457591-39457671 2.17e-01 80 chr19:42377183-42377263 3.20e-01 80 chr19:8388840-8388920 3.76e-03 4_[+4(1.72e-05)]_68 chr19:13050085-13050165 4.48e-01 80 chr22:21221017-21221097 2.27e-03 32_[+5(5.00e-06)]_40 chr22:21408382-21408462 6.33e-01 80 chr8:146016805-146016885 6.97e-01 80 chr22:19678051-19678131 8.36e-05 23_[+4(1.72e-05)]_1_[+5(5.00e-06)]_\ 40 chr19:55902519-55902599 9.43e-01 80 chr22:20082061-20082141 5.53e-05 4_[+4(1.72e-05)]_55_[+3(1.89e-05)]_\ 5 chr1:109941153-109941233 1.50e-01 80 chr12:6977571-6977651 4.16e-02 69_[+4(4.86e-05)]_3 chr22:20809553-20809633 5.85e-01 80 chr1:207195557-207195637 1.43e-01 80 chr5:177639832-177639912 2.68e-02 80 chr22:21126597-21126677 4.67e-03 [+1(8.74e-05)]_72 chr19:8387650-8387730 9.27e-01 80 chr22:19821045-19821125 6.15e-01 80 chr9:140507757-140507837 1.25e-01 80 chr5:177633450-177633530 8.52e-02 48_[+1(8.74e-05)]_24 chr8:146015924-146016004 9.91e-01 80 chr16:89807970-89808050 5.99e-01 80 chr16:2014122-2014202 6.41e-01 80 chr21:44257129-44257209 3.71e-02 23_[+1(4.39e-05)]_49 chr17:25418288-25418368 9.41e-01 80 chr17:25409867-25409947 6.48e-01 80 chr22:19175065-19175145 6.21e-01 80 chr6:30688706-30688786 8.65e-01 80 chr9:138841556-138841636 2.57e-01 80 chr22:20175132-20175212 3.03e-01 80 chr22:21304372-21304452 7.52e-02 80 chr22:22445949-22446029 4.15e-01 80 chr22:19356573-19356653 6.38e-01 80 chr22:19363153-19363233 8.55e-02 30_[+1(4.39e-05)]_42 chr4:174254657-174254737 8.57e-02 80 chr22:20086775-20086855 2.29e-04 13_[+4(1.72e-05)]_43_[+3(1.89e-05)]_\ 8 chr13:90939943-90940023 5.71e-01 80 chr9:139618657-139618737 7.87e-02 80 chr19:39126000-39126080 2.65e-01 80 chr12:57118529-57118609 9.89e-01 80 chr11:65191446-65191526 2.18e-01 80 chr22:23274667-23274747 8.29e-02 80 chr6:7116064-7116144 2.25e-02 70_[+2(1.87e-05)]_2 chr19:10227023-10227103 8.25e-01 80 chr1:35859995-35860075 4.43e-02 80 chr11:813720-813800 2.10e-03 13_[+2(1.87e-05)]_59 chr7:105494536-105494616 3.55e-01 80 chr7:153102246-153102326 5.67e-02 80 chr22:19453737-19453817 3.29e-01 80 chr19:42364776-42364856 3.06e-02 34_[+3(8.85e-05)]_38 chr19:49993889-49993969 6.37e-01 80 chr22:22936381-22936461 6.85e-01 80 chr22:19445495-19445575 4.23e-01 80 chr22:20989276-20989356 3.56e-01 80 chr6:31752453-31752533 1.57e-01 11_[+3(6.32e-05)]_61 chr1:156461935-156462015 7.13e-02 80 chr11:63993022-63993102 2.96e-01 80 chr22:19444217-19444297 9.92e-01 80 chr3:39456091-39456171 3.91e-01 80 chr9:139620800-139620880 9.99e-01 80 chr9:131591454-131591534 6.71e-01 80 chr22:22025158-22025238 5.58e-01 80 chr17:80561956-80562036 2.60e-01 80 chr22:22068421-22068501 2.98e-01 62_[+1(8.74e-05)]_10 chr2:219271703-219271783 1.03e-01 80 chr3:47879425-47879505 6.69e-02 45_[+3(3.75e-05)]_27 chr1:45986982-45987062 9.95e-01 80 chr22:20821140-20821220 9.11e-01 80 chr5:862094-862174 9.02e-01 80 chr13:90685529-90685609 8.97e-01 80 chr7:139666858-139666938 3.67e-01 80 chr16:67244749-67244829 9.01e-01 80 chr22:20116467-20116547 8.01e-01 80 chr22:20870755-20870835 4.20e-02 2_[+3(6.32e-05)]_70 chr9:139565092-139565172 9.79e-01 80 chr22:22477893-22477973 7.75e-01 80 chr10:76992134-76992214 9.61e-01 80 chr22:39715092-39715172 3.75e-01 80 chr12:54677007-54677087 6.81e-01 80 chr16:2204922-2205002 7.47e-01 80 chr6:27095044-27095124 8.33e-01 80 chr22:23052761-23052841 3.79e-01 80 chr17:80015008-80015088 9.30e-01 80 chr3:39455400-39455480 8.75e-01 80 chr13:91834542-91834622 6.10e-04 6_[+5(5.00e-06)]_66 chr22:19946162-19946242 2.52e-01 80 chr19:799502-799582 3.17e-01 80 chr11:5264695-5264775 6.62e-01 80 chr7:25164289-25164369 5.51e-01 80 chr11:62434111-62434191 1.46e-01 80 chr5:177633672-177633752 1.14e-01 80 chr22:21083213-21083293 9.78e-01 80 chr17:56404988-56405068 2.70e-03 37_[+1(8.74e-05)]_2_[+3(1.89e-05)]_\ 25 chr15:69749102-69749182 2.41e-01 80 chr22:21229734-21229814 8.44e-01 80 chr21:44254084-44254164 1.44e-01 14_[+3(3.75e-05)]_58 chr1:28833897-28833977 4.06e-01 80 chr19:10226055-10226135 3.85e-01 80 chr3:15105939-15106019 8.27e-01 80 chr22:22093486-22093566 3.72e-01 80 chr22:20240819-20240899 5.89e-02 5_[+3(8.85e-05)]_67 chr2:91800570-91800650 3.98e-01 80 chr12:123465744-12346582 4.21e-01 80 chr22:19942113-19942193 5.02e-02 80 chr22:19437004-19437084 1.06e-01 3_[+1(4.39e-05)]_69 chr22:23034134-23034214 6.16e-01 80 chr6:16130251-16130331 5.40e-01 80 chr22:21922833-21922913 6.77e-01 80 chr9:139620046-139620126 1.23e-01 61_[+3(6.32e-05)]_11 chr1:23856422-23856502 3.64e-02 80 chr5:81570753-81570833 5.93e-01 80 chr22:21187600-21187680 1.23e-01 80 chr2:85767198-85767278 2.32e-02 59_[+4(7.82e-05)]_13 chr6:26131278-26131358 2.15e-01 80 chr22:21953660-21953740 3.96e-02 80 chr10:47056575-47056655 5.12e-01 80 chr12:120638477-12063855 2.89e-01 80 chr17:73771239-73771319 8.61e-01 80 chr19:8389908-8389988 2.19e-01 80 chr1:76262819-76262899 1.23e-01 6_[+2(1.87e-05)]_66 chr20:57195143-57195223 5.20e-01 80 chr11:93474126-93474206 7.89e-01 80 chr1:28833080-28833160 1.23e-01 55_[+3(1.89e-05)]_17 chr16:88877344-88877424 3.22e-01 80 chr22:23250544-23250624 5.38e-02 50_[+1(4.39e-05)]_22 chr22:22554209-22554289 5.55e-01 80 chr22:19410319-19410399 1.59e-01 80 chr1:180133542-180133622 8.62e-01 80 chr6:133136216-133136296 1.89e-01 80 chr16:2203035-2203115 5.69e-02 18_[+1(4.39e-05)]_54 chr19:54715121-54715201 3.98e-02 80 chr1:1335496-1335576 4.61e-01 80 chr9:136024102-136024182 7.43e-01 80 chr5:137805862-137805942 7.98e-02 80 chr22:19394251-19394331 1.94e-01 80 chr1:228296453-228296533 6.19e-01 80 chr19:8389708-8389788 3.25e-01 80 chr22:22555930-22556010 6.24e-01 80 chr9:136027090-136027170 1.77e-01 80 chr10:71094768-71094848 3.51e-01 80 chr3:195435110-195435190 3.69e-01 80 chr5:137802556-137802636 7.08e-01 80 chr19:12896900-12896980 8.34e-01 80 chr22:19074071-19074151 4.10e-01 80 chr20:31219746-31219826 1.48e-02 70_[+1(4.39e-05)]_2 chr12:123848527-12384860 7.76e-01 80 chr6:74230004-74230084 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