******************************************************************************** MEME - Motif discovery tool ******************************************************************************** MEME version 5.3.3 (Release date: Sun Feb 7 15:39:52 2021 -0800) For further information on how to interpret these results please access https://meme-suite.org/meme. To get a copy of the MEME Suite software please access https://meme-suite.org. ******************************************************************************** ******************************************************************************** REFERENCE ******************************************************************************** If you use this program in your research, please cite: Timothy L. Bailey and Charles Elkan, "Fitting a mixture model by expectation maximization to discover motifs in biopolymers", Proceedings of the Second International Conference on Intelligent Systems for Molecular Biology, pp. 28-36, AAAI Press, Menlo Park, California, 1994. ******************************************************************************** ******************************************************************************** TRAINING SET ******************************************************************************** PRIMARY SEQUENCES= ../result/final_prediction/K562/fasta/RankLinear0.6_40/SNIP1.fasta CONTROL SEQUENCES= --none-- ALPHABET= ACGT Sequence name Weight Length Sequence name Weight Length ------------- ------ ------ ------------- ------ ------ chr17:75457026-75457106 1.0000 80 chr11:35639696-35639776 1.0000 80 chr12:8171626-8171706 1.0000 80 chr15:78931243-78931323 1.0000 80 chr11:65339872-65339952 1.0000 80 chr6:117083096-117083176 1.0000 80 chr17:41985000-41985080 1.0000 80 chr14:93930765-93930845 1.0000 80 chr1:33565351-33565431 1.0000 80 chr19:44031511-44031591 1.0000 80 chr17:4959009-4959089 1.0000 80 chr16:18603448-18603528 1.0000 80 chr1:116512306-116512386 1.0000 80 chr22:45645947-45646027 1.0000 80 chr3:141752313-141752393 1.0000 80 chr9:35115898-35115978 1.0000 80 chr12:114196488-11419656 1.0000 80 chrX:120181426-120181506 1.0000 80 chr9:37411413-37411493 1.0000 80 chr10:134298591-13429867 1.0000 80 chr14:102512774-10251285 1.0000 80 chr15:46007304-46007384 1.0000 80 chr1:230907701-230907781 1.0000 80 chr11:61472432-61472512 1.0000 80 chr1:109783587-109783667 1.0000 80 chr16:23711920-23712000 1.0000 80 chr18:12946707-12946787 1.0000 80 chr4:159969338-159969418 1.0000 80 chr17:4901027-4901107 1.0000 80 chr10:82075978-82076058 1.0000 80 chr1:175190895-175190975 1.0000 80 chr22:32026936-32027016 1.0000 80 chr3:47545736-47545816 1.0000 80 chr10:89102289-89102369 1.0000 80 chr2:70484571-70484651 1.0000 80 chr15:102286575-10228665 1.0000 80 chr7:43152987-43153067 1.0000 80 chr10:88854566-88854646 1.0000 80 chrX:153402186-153402266 1.0000 80 chr19:51109377-51109457 1.0000 80 chr2:583290-583370 1.0000 80 chr14:101012893-10101297 1.0000 80 chr8:21911941-21912021 1.0000 80 chr17:1466234-1466314 1.0000 80 chr17:2310370-2310450 1.0000 80 chr9:107690521-107690601 1.0000 80 chr9:38026383-38026463 1.0000 80 chr1:162660877-162660957 1.0000 80 chr11:125011891-12501197 1.0000 80 chr15:84841379-84841459 1.0000 80 chr2:39002411-39002491 1.0000 80 chr11:43963667-43963747 1.0000 80 chr1:118149743-118149823 1.0000 80 chr20:48610038-48610118 1.0000 80 chr7:139529004-139529084 1.0000 80 chr4:140477317-140477397 1.0000 80 chr13:99660970-99661050 1.0000 80 chr1:109791985-109792065 1.0000 80 chr8:21999524-21999604 1.0000 80 chr10:81586248-81586328 1.0000 80 chr3:169850254-169850334 1.0000 80 chr12:133065736-13306581 1.0000 80 chr9:32384796-32384876 1.0000 80 chrX:139139338-139139418 1.0000 80 chr10:64576281-64576361 1.0000 80 chr2:54785578-54785658 1.0000 80 chr13:100633171-10063325 1.0000 80 chr8:28514922-28515002 1.0000 80 chr7:44622313-44622393 1.0000 80 chr9:99983967-99984047 1.0000 80 chr13:99852396-99852476 1.0000 80 chr11:64513487-64513567 1.0000 80 chr10:96162063-96162143 1.0000 80 chr14:75229871-75229951 1.0000 80 chr17:21454502-21454582 1.0000 80 chr5:115420173-115420253 1.0000 80 chr11:5962130-5962210 1.0000 80 chr11:120302503-12030258 1.0000 80 chr14:55852360-55852440 1.0000 80 chr14:74769721-74769801 1.0000 80 chr4:2390322-2390402 1.0000 80 chr17:65989397-65989477 1.0000 80 chr3:44727185-44727265 1.0000 80 chr12:116714856-11671493 1.0000 80 chr7:92384486-92384566 1.0000 80 chr16:640441-640521 1.0000 80 chr3:181412960-181413040 1.0000 80 chr9:123836709-123836789 1.0000 80 chr18:21290260-21290340 1.0000 80 chr9:124030102-124030182 1.0000 80 chr19:46283893-46283973 1.0000 80 chr7:98977986-98978066 1.0000 80 chr8:102904139-102904219 1.0000 80 chr2:219264488-219264568 1.0000 80 chr2:219261202-219261282 1.0000 80 chrX:110924896-110924976 1.0000 80 chr20:42073783-42073863 1.0000 80 chr17:43227050-43227130 1.0000 80 chr8:144853287-144853367 1.0000 80 chr15:85177067-85177147 1.0000 80 chr11:120039828-12003990 1.0000 80 chr2:128643674-128643754 1.0000 80 chr3:121264854-121264934 1.0000 80 chr2:241887620-241887700 1.0000 80 chr1:46665164-46665244 1.0000 80 chr6:30434132-30434212 1.0000 80 chr18:12946910-12946990 1.0000 80 chr17:21935018-21935098 1.0000 80 chr2:241075700-241075780 1.0000 80 chr10:70715199-70715279 1.0000 80 chr6:110012349-110012429 1.0000 80 chr15:67187875-67187955 1.0000 80 chr3:186545502-186545582 1.0000 80 chr9:95571441-95571521 1.0000 80 chr7:16685320-16685400 1.0000 80 chr1:8377962-8378042 1.0000 80 chr10:103336406-10333648 1.0000 80 chr2:38603680-38603760 1.0000 80 chr4:78739745-78739825 1.0000 80 chr16:3239219-3239299 1.0000 80 chr8:99058133-99058213 1.0000 80 chr19:18315791-18315871 1.0000 80 chrX:18443780-18443860 1.0000 80 chr7:23762301-23762381 1.0000 80 chr12:65073277-65073357 1.0000 80 chrX:151081373-151081453 1.0000 80 chr17:41984022-41984102 1.0000 80 chr13:101261374-10126145 1.0000 80 chr12:7342132-7342212 1.0000 80 chr15:52857868-52857948 1.0000 80 chr1:204380090-204380170 1.0000 80 chr17:19281195-19281275 1.0000 80 chr16:3055095-3055175 1.0000 80 chr12:131892044-13189212 1.0000 80 chr6:35226663-35226743 1.0000 80 chr5:172878211-172878291 1.0000 80 chr8:125985444-125985524 1.0000 80 chr7:140188905-140188985 1.0000 80 chr9:34523123-34523203 1.0000 80 chr7:5462569-5462649 1.0000 80 chr16:640644-640724 1.0000 80 chr12:49297813-49297893 1.0000 80 chr15:51914501-51914581 1.0000 80 chr21:44494855-44494935 1.0000 80 chr1:27929822-27929902 1.0000 80 chr16:89359711-89359791 1.0000 80 chr17:27396714-27396794 1.0000 80 chr6:28411285-28411365 1.0000 80 chr16:88589075-88589155 1.0000 80 chr9:107730509-107730589 1.0000 80 chr14:20774101-20774181 1.0000 80 chr5:173312734-173312814 1.0000 80 chr9:73034076-73034156 1.0000 80 chr1:203598832-203598912 1.0000 80 chr12:50478851-50478931 1.0000 80 chr5:157376035-157376115 1.0000 80 chrX:44402060-44402140 1.0000 80 chr16:14927439-14927519 1.0000 80 chr3:14443837-14443917 1.0000 80 chr16:90039541-90039621 1.0000 80 chr11:122526714-12252679 1.0000 80 chr6:149068091-149068171 1.0000 80 chr3:14272388-14272468 1.0000 80 chr16:89767315-89767395 1.0000 80 chr2:205409946-205410026 1.0000 80 chr16:30406610-30406690 1.0000 80 chr14:59654964-59655044 1.0000 80 chr1:38157268-38157348 1.0000 80 chr1:22014020-22014100 1.0000 80 chr19:605287-605367 1.0000 80 chr1:156471253-156471333 1.0000 80 chr16:90015047-90015127 1.0000 80 chr17:18128675-18128755 1.0000 80 chr17:55498171-55498251 1.0000 80 chrX:15873550-15873630 1.0000 80 chr1:231176211-231176291 1.0000 80 chr20:814677-814757 1.0000 80 chr6:111926725-111926805 1.0000 80 chr12:117197653-11719773 1.0000 80 chr4:184328406-184328486 1.0000 80 chr16:71518523-71518603 1.0000 80 chr2:219524259-219524339 1.0000 80 chr2:148601459-148601539 1.0000 80 chr21:46294178-46294258 1.0000 80 chr10:88853837-88853917 1.0000 80 chr19:7599082-7599162 1.0000 80 chr17:7210201-7210281 1.0000 80 chr11:57103380-57103460 1.0000 80 chr11:18032806-18032886 1.0000 80 chr2:231921290-231921370 1.0000 80 chr14:103671513-10367159 1.0000 80 chr3:141206552-141206632 1.0000 80 chr5:104725142-104725222 1.0000 80 chr2:38751053-38751133 1.0000 80 chr19:55988613-55988693 1.0000 80 chr2:131099556-131099636 1.0000 80 chr8:28559765-28559845 1.0000 80 chr9:35732205-35732285 1.0000 80 chr7:72299052-72299132 1.0000 80 chr19:18705077-18705157 1.0000 80 chr1:227915926-227916006 1.0000 80 chr9:136243383-136243463 1.0000 80 chr2:120770482-120770562 1.0000 80 chr3:128598627-128598707 1.0000 80 chr13:50699423-50699503 1.0000 80 chr16:30670037-30670117 1.0000 80 chr20:62886863-62886943 1.0000 80 chr16:31008143-31008223 1.0000 80 chr1:28696637-28696717 1.0000 80 chr1:231175544-231175624 1.0000 80 chr16:74637696-74637776 1.0000 80 chr5:137558680-137558760 1.0000 80 chr12:6643341-6643421 1.0000 80 chr19:39177234-39177314 1.0000 80 chr3:182896793-182896873 1.0000 80 chr3:182896589-182896669 1.0000 80 chr12:46123710-46123790 1.0000 80 chr17:28705706-28705786 1.0000 80 chr17:58042315-58042395 1.0000 80 chr7:151649184-151649264 1.0000 80 chr6:28785600-28785680 1.0000 80 chr19:42829687-42829767 1.0000 80 chr14:24685256-24685336 1.0000 80 chr1:162035381-162035461 1.0000 80 chr6:25153534-25153614 1.0000 80 chr11:14112106-14112186 1.0000 80 chr1:10057-10137 1.0000 80 chr3:150421886-150421966 1.0000 80 chr2:129494276-129494356 1.0000 80 chr17:26646364-26646444 1.0000 80 chr8:9008621-9008701 1.0000 80 chr6:40106368-40106448 1.0000 80 chr11:12133177-12133257 1.0000 80 chr7:77428654-77428734 1.0000 80 chr17:7819533-7819613 1.0000 80 chr10:102295550-10229563 1.0000 80 chr1:28995031-28995111 1.0000 80 chr19:46010603-46010683 1.0000 80 chr6:64308750-64308830 1.0000 80 chr1:37980714-37980794 1.0000 80 chr12:14720797-14720877 1.0000 80 chr2:234475526-234475606 1.0000 80 chr19:46144785-46144865 1.0000 80 chr17:66509218-66509298 1.0000 80 chr11:19734060-19734140 1.0000 80 chr1:221458468-221458548 1.0000 80 chr10:74442613-74442693 1.0000 80 chr18:12302547-12302627 1.0000 80 chr1:156095891-156095971 1.0000 80 chr2:191184625-191184705 1.0000 80 ******************************************************************************** ******************************************************************************** COMMAND LINE SUMMARY ******************************************************************************** This information can also be useful in the event you wish to report a problem with the MEME software. command: meme -oc ../result/final_prediction/K562/inference_raw/MEME/RankLinear0.6_40_SNIP1/ -dna -nmotifs 5 -w 8 -maxsize 250000 -nostatus ../result/final_prediction/K562/fasta/RankLinear0.6_40/SNIP1.fasta model: mod= zoops nmotifs= 5 evt= inf objective function: em= E-value of product of p-values starts= E-value of product of p-values strands: + width: minw= 8 maxw= 8 nsites: minsites= 2 maxsites= 250 wnsites= 0.8 theta: spmap= uni spfuzz= 0.5 em: prior= dirichlet b= 0.01 maxiter= 50 distance= 1e-05 trim: wg= 11 ws= 1 endgaps= yes data: n= 20000 N= 250 sample: seed= 0 hsfrac= 0 searchsize= 20000 norand= no csites= 1000 Letter frequencies in dataset: A 0.198 C 0.296 G 0.307 T 0.199 Background letter frequencies (from file dataset with add-one prior applied): A 0.198 C 0.296 G 0.307 T 0.199 Background model order: 0 ******************************************************************************** ******************************************************************************** MOTIF GGGCYCRS MEME-1 width = 8 sites = 128 llr = 808 E-value = 1.6e-014 ******************************************************************************** -------------------------------------------------------------------------------- Motif GGGCYCRS MEME-1 Description -------------------------------------------------------------------------------- Simplified A 23::::5: pos.-specific C ::2a7a:6 probability G 877:::54 matrix T ::1:3::: bits 2.3 2.1 1.9 * * 1.6 * * Relative 1.4 * * Entropy 1.2 * * * (9.1 bits) 0.9 ** **** 0.7 ** ***** 0.5 ******** 0.2 ******** 0.0 -------- Multilevel GGGCCCGC consensus AC T AG sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GGGCYCRS MEME-1 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr12:14720797-14720877 27 4.40e-05 TGGTGGCCTG GGGCCCAC CCCGCCTAGG chr16:31008143-31008223 13 4.40e-05 CGGGGACCTG GGGCCCAC CCTCCCACGC chr15:51914501-51914581 42 4.40e-05 GCCACGGGTG GGGCCCAC CAACATCTCA chr16:3055095-3055175 65 4.40e-05 GCAGCGGGCG GGGCCCAC AGCACGTG chr10:103336406-10333648 31 4.40e-05 tgtttacact gggcccac aggattactc chr15:67187875-67187955 48 4.40e-05 ttcctgggtg gggcccac aagattaaag chr7:92384486-92384566 47 4.40e-05 CATTGCTGTG GGGCCCAC TTCTAGGCTT chr8:21999524-21999604 23 4.40e-05 CTCGCGCGTG GGGCCCAC AGTGGAGCCA chr7:139529004-139529084 53 4.40e-05 CACATTGTGG GGGCCCAC TCCATGTGAT chr20:48610038-48610118 46 4.40e-05 ggttaaggtg gggcccac taggtccctc chr1:162660877-162660957 37 4.40e-05 CTGACACAGC GGGCCCAC AGGCTGCTCC chr3:47545736-47545816 34 4.40e-05 AACCCTGCCT GGGCCCAC CTGCCACGTG chr18:12946707-12946787 12 4.40e-05 ATAAGAGGTG GGGCCCAC CTCTTAAAGT chr9:37411413-37411493 11 4.40e-05 AAGGGAAGTG GGGCCCAC TGAAGGCTGG chr9:35115898-35115978 33 4.40e-05 CGCAACGCCC GGGCCCAC CCTCTCCCTT chr3:141752313-141752393 22 4.40e-05 CAACTTAGTG GGGCCCAC AGAATTAAGT chr22:45645947-45646027 39 4.40e-05 ATGGATGGTG GGGCCCAC ACGTGGAAGG chr1:33565351-33565431 54 4.40e-05 CTCCAGAGTG GGGCCCAC AGCCTGGCGG chr12:8171626-8171706 43 4.40e-05 AACAGTTTTG GGGCCCAC CACCCTTGGC chr9:35732205-35732285 13 1.42e-04 GCGGCGCCCT GGGCCCGC GCTCTATGGT chr2:38751053-38751133 41 1.42e-04 CATGGATGTG GGGCCCGC ACGTGGTTCT chr11:57103380-57103460 14 1.42e-04 GACGCGAGTC GGGCCCGC CTGCGAGACA chr9:99983967-99984047 70 1.42e-04 TCCCGCCTGA GGGCCCGC CTG chr9:107690521-107690601 69 1.42e-04 CGTGGAGCCG GGGCCCGC CCCT chr8:21911941-21912021 20 1.42e-04 CAGAGGTGTG GGGCCCGC AGCCGCGTGC chr11:43963667-43963747 3 1.70e-04 GG GAGCCCAC CCCTTCTTCC chr2:583290-583370 47 1.70e-04 GGACGGTGGC GAGCCCAC GCTTGCCAGG chr14:103671513-10367159 16 2.62e-04 cttcgctatg gggcccag aaggccgcag chr6:111926725-111926805 26 2.62e-04 TAACCCGGCG GGGCTCGC TGGCCTGAAA chrX:15873550-15873630 60 2.62e-04 TCTGTTCCCT GGGCTCGC CTCGCCCATC chr16:90015047-90015127 37 2.62e-04 GCGGACTCCG GGGCTCGC AGACTCGCGA chr1:38157268-38157348 49 2.62e-04 CGGCTCGGCG GGGCTCGC CGTCTACACG chr16:88589075-88589155 51 2.62e-04 GGGCCGGCCA GGGCCCAG AGGAGGGACA chr3:181412960-181413040 50 2.62e-04 AGGTTCTCCT GGGCTCGC CGTTTCGCCC chr13:99852396-99852476 30 2.62e-04 TCGCTCCGCC GGGCTCGC CGGGCCGGGG chr4:140477317-140477397 58 2.62e-04 GCGAGCTCTG GGGCTCGC GAGTTTggag chr7:43152987-43153067 54 2.62e-04 GCCTCCGCAC GGGCTCGC CGGTGCTCGC chr11:61472432-61472512 39 2.62e-04 TGCCGTGCCC GGGCTCGC CTGAGCTCGG chr16:18603448-18603528 37 2.62e-04 gattggatta gggcccag cctaatgacc chr13:50699423-50699503 60 3.55e-04 GCGAGCTCTC GAGCCCGC GCAGGGATCG chr14:59654964-59655044 70 3.55e-04 CGATCCTTCA GAGCCCGC GCC chr17:21454502-21454582 69 3.55e-04 CAGGCTGTTG GAGCCCGC GAAG chr13:100633171-10063325 9 3.55e-04 AGACCTGG GAGCCCGC CTGGGCCTCA chr18:12302547-12302627 5 4.68e-04 TGTG GGCCCCAC CAGCCTCCCT chr19:46144785-46144865 11 4.68e-04 TGAACTAGCT GGCCCCAC TCTAGGTTAC chr8:9008621-9008701 12 4.68e-04 TGGAGCACGT GGGCCCGG GAGGCGCTTC chr16:30670037-30670117 33 4.68e-04 TGGAGGAGCT GGGCCCGG AGGAGGCCCC chr2:120770482-120770562 28 4.68e-04 CAGCCCGGCC GGGCCCGG CCTCGCCGGT chr1:156471253-156471333 1 4.68e-04 . GGGCCCGG CTCGGCAGAC chr3:14272388-14272468 47 4.68e-04 cacagctgtg ggccccac cttcctgaag chr16:89359711-89359791 39 4.68e-04 AAAGCGAGTG GGCCCCAC TTCTGTGCTG chr13:101261374-10126145 53 4.68e-04 gtggtgtgtg ggccccac cctctaacat chr7:23762301-23762381 45 4.68e-04 agctgtggtg ggccccac ccagttcaag chr15:85177067-85177147 56 4.68e-04 TGACAGCTGC GGGCCCGG CGAGCCGAGC chr14:55852360-55852440 22 4.68e-04 CACAAGTGTG GGCCCCAC CCCTCACCTC chr8:28514922-28515002 36 4.68e-04 CGACTAAGTG GGCCCCAC TGACCTGCTG chr15:78931243-78931323 54 4.68e-04 ATGAGGAGTG GGCCCCAC CAGCCTCTGC chr2:234475526-234475606 38 5.56e-04 CGGGCAAGGT GAGCTCGC TTACAAGTCC chr1:37980714-37980794 57 5.56e-04 gactccggaa gagctcgc gaatccattt chr2:148601459-148601539 9 5.56e-04 CGCGTCGC GAGCTCGC CTGGGCAGCT chr5:157376035-157376115 9 5.56e-04 AGGAGAGC GAGCCCAG AAGAAAGTAG chr9:95571441-95571521 33 5.56e-04 CGTCCCGCGC GAGCCCAG GAGAACCCGC chr2:241887620-241887700 31 5.56e-04 GTTCTGACCT GAGCCCAG AGGACTTCCC chrX:110924896-110924976 46 5.56e-04 TGAGCCAGCC GAGCTCGC CTCAGAGCCC chr9:123836709-123836789 5 5.56e-04 GCTG GAGCCCAG GCTGCGTCCG chr16:640441-640521 54 5.56e-04 GCTGGGCACG GAGCTCGC CCTCGGCCCG chr5:115420173-115420253 12 5.56e-04 AGGCTCGGGG GAGCTCGC TCAAATGCCT chr2:39002411-39002491 20 5.56e-04 aggatcgctt gagctcgc ttgagctcag chr17:2310370-2310450 35 5.56e-04 TGAGAAACCA GAGCCCAG TCGAGCTCTG chr19:39177234-39177314 7 6.32e-04 AAGGTA GGCCTCAC CATCTCCTCC chr3:141206552-141206632 20 6.32e-04 TTCGTTTCCT GGGCTCGG CGAGCCTGGG chr4:184328406-184328486 43 6.32e-04 GAGCTCGGAG GGGCTCGG GGTGGCGGGG chr16:90039541-90039621 26 6.32e-04 GTGTCCTCCT GGGCTCGG CGGCGTTCGg chr9:34523123-34523203 37 6.32e-04 gggctcggcc gggctcgg cGGCCAGCAA chr16:71518523-71518603 30 6.99e-04 CCTTGCACCC AGGCTCAC ACGCGTACTC chr7:140188905-140188985 47 6.99e-04 atctagtttg ggtcccac aatggccttt chr4:78739745-78739825 14 6.99e-04 TCCTCCCTCG GGTCCCAC AGCCGGCCGG chr2:241075700-241075780 21 6.99e-04 GCGGCGCTCT AGGCTCAC TTCCGGCCTC chr11:65339872-65339952 55 6.99e-04 TGCGCGACGT GGTCCCAC AACCGTTGCC chr11:12133177-12133257 14 7.65e-04 AAGCCTGTAG GGCCCCGC CAGGCCTACA chr6:25153534-25153614 25 7.65e-04 GGGGGAGGTG GGCCCCGC GCACGTTAAA chr17:18128675-18128755 30 7.65e-04 AGTCCCGGCA GGCCCCGC GCCGCGGCGC chr12:7342132-7342212 53 7.65e-04 GCAGTCTTAA GGCCCCGC CTTTTCAGAC chr16:30406610-30406690 68 9.01e-04 CGACCCCCAC AGGCCCGC AGCTC chr2:38603680-38603760 7 9.01e-04 AAACGC GAGCCCGG GGACAGAGCC chrX:153402186-153402266 37 9.01e-04 GACATGGCCC AGGCCCGC TCAGGATCGC chr3:182896793-182896873 70 1.01e-03 gagcacagag aagcccac gca chr8:28559765-28559845 70 1.01e-03 CCCTAGAGCC GGCCTCGC GCT chr21:46294178-46294258 60 1.01e-03 CACTAGAAAC GGCCCCAG AATGGGCTGA chr8:125985444-125985524 54 1.01e-03 TTCCTAGAAC GGCCCCAG CAAAGCCGCC chr9:124030102-124030182 25 1.01e-03 TGAGCTCTTT GGCCCCAG CCCAGCTCAG chr11:35639696-35639776 6 1.01e-03 CGCCA GGCCCCAG ACTCCGGCTC chr6:28785600-28785680 32 1.16e-03 aggatcgctt gagctcgg gagttagttg chr9:136243383-136243463 9 1.16e-03 GGGGAGCG AGGCCCAG GGTCCCCCGG chr19:18705077-18705157 12 1.16e-03 TTCTGCATCC AGGCTCGC CACTGGTCGT chr8:99058133-99058213 11 1.16e-03 gaggtcgctt gagctcgg taggtcgagg chr16:3239219-3239299 51 1.16e-03 GCAGTGATCG AGGCTCGC AGACCCTCAG chr7:16685320-16685400 54 1.16e-03 GACAGCGGGC GAGCTCGG GCGAGCCAGG chr10:70715199-70715279 54 1.16e-03 agattcgctt gagctcgg gaggcagagg chr6:30434132-30434212 36 1.16e-03 AGGCCCGGGC GAGCTCGG GCGGGACCGG chr12:116714856-11671493 40 1.16e-03 ACAATCCTCC AGGCTCGC CCCGTTCGCC chr10:88854566-88854646 39 1.16e-03 AGGGAGGAAG GGTCCCGC GCGGGTTGCC chr10:134298591-13429867 1 1.16e-03 . AGGCTCGC CTGTGAAGCG chr19:55988613-55988693 17 1.34e-03 TGTTAAATGG GACCCCGC TCTTTCAGGG chr20:814677-814757 37 1.34e-03 gaggactctg aggctcag agaggcaagt chr17:19281195-19281275 30 1.34e-03 AGCTGCGGAG AGGCTCAG CCACCGGAAG chr2:219264488-219264568 4 1.34e-03 GCC GGTCCCAG AAGTGGCGAA chr13:99660970-99661050 62 1.34e-03 gagttggcgg ggtcccag gaggatcatt chrX:151081373-151081453 39 1.45e-03 TGGCGGAGGG AAGCCCGC CCAGGCTCTA chr1:221458468-221458548 72 1.60e-03 gtggaagggg gaccccag c chr10:88853837-88853917 10 1.60e-03 CATATACAG AGGCCCGG GGTGACGGCG chr18:21290260-21290340 52 1.60e-03 CCTTTTAAAA AGCCCCAC GAGGTTATCT chr1:116512306-116512386 70 1.60e-03 AATGCCTGTC AGCCCCAC CGT chr10:102295550-10229563 9 1.71e-03 CACCCTCA GGCCTCGG CTCCGCGTTC chr21:44494855-44494935 55 1.71e-03 GCTCGGCGGA AAGCTCGC CAGGCGACCC chr11:5962130-5962210 48 1.71e-03 aaacccgcta aagctcgc aagaaagaat chr6:110012349-110012429 41 1.83e-03 GCAGCACGCA GGTCCCGG GAGCCTCTAC chr10:64576281-64576361 41 1.83e-03 GGATCGCTGG GGTCCCGG GCGCGCGGCC chr9:107730509-107730589 42 1.90e-03 CACACGTCGC GATCTCGC CGCTTTAAGC chr17:65989397-65989477 67 1.90e-03 GGCGCCCTGG GATCTCGC GGGCGG chr17:75457026-75457106 33 1.90e-03 TGACTTAGCA GATCCCAG TCTGTGTTAC chr7:77428654-77428734 33 2.01e-03 GGCGTTCAGG GGTCTCGG GTGGCTAGCC chr19:7599082-7599162 23 2.01e-03 GCGCGGAGTG GACCCCGG CTGCGGCCCC chr16:640644-640724 63 2.09e-03 ACGGGTCCGG GATCTCAG GGGAAGGTGT chr22:32026936-32027016 16 2.17e-03 GCCCCCTCTG AGCCCCAG TCCTGCTGGG chr1:203598832-203598912 50 2.29e-03 GGTTGTGCCG AGCCTCAG ACCCTTCTCC chr11:64513487-64513567 73 2.29e-03 TGGTCCGGGA AGCCTCAG chr9:73034076-73034156 69 2.38e-03 ATCTGAGGAC AGTCCCAG TTCT -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GGGCYCRS MEME-1 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr12:14720797-14720877 4.4e-05 26_[+1]_46 chr16:31008143-31008223 4.4e-05 12_[+1]_60 chr15:51914501-51914581 4.4e-05 41_[+1]_31 chr16:3055095-3055175 4.4e-05 64_[+1]_8 chr10:103336406-10333648 4.4e-05 30_[+1]_42 chr15:67187875-67187955 4.4e-05 47_[+1]_25 chr7:92384486-92384566 4.4e-05 46_[+1]_26 chr8:21999524-21999604 4.4e-05 22_[+1]_50 chr7:139529004-139529084 4.4e-05 52_[+1]_20 chr20:48610038-48610118 4.4e-05 45_[+1]_27 chr1:162660877-162660957 4.4e-05 36_[+1]_36 chr3:47545736-47545816 4.4e-05 33_[+1]_39 chr18:12946707-12946787 4.4e-05 11_[+1]_61 chr9:37411413-37411493 4.4e-05 10_[+1]_62 chr9:35115898-35115978 4.4e-05 32_[+1]_40 chr3:141752313-141752393 4.4e-05 21_[+1]_51 chr22:45645947-45646027 4.4e-05 38_[+1]_34 chr1:33565351-33565431 4.4e-05 53_[+1]_19 chr12:8171626-8171706 4.4e-05 42_[+1]_30 chr9:35732205-35732285 0.00014 12_[+1]_60 chr2:38751053-38751133 0.00014 40_[+1]_32 chr11:57103380-57103460 0.00014 13_[+1]_59 chr9:99983967-99984047 0.00014 69_[+1]_3 chr9:107690521-107690601 0.00014 68_[+1]_4 chr8:21911941-21912021 0.00014 19_[+1]_53 chr11:43963667-43963747 0.00017 2_[+1]_70 chr2:583290-583370 0.00017 46_[+1]_26 chr14:103671513-10367159 0.00026 15_[+1]_57 chr6:111926725-111926805 0.00026 25_[+1]_47 chrX:15873550-15873630 0.00026 59_[+1]_13 chr16:90015047-90015127 0.00026 36_[+1]_36 chr1:38157268-38157348 0.00026 48_[+1]_24 chr16:88589075-88589155 0.00026 50_[+1]_22 chr3:181412960-181413040 0.00026 49_[+1]_23 chr13:99852396-99852476 0.00026 29_[+1]_43 chr4:140477317-140477397 0.00026 57_[+1]_15 chr7:43152987-43153067 0.00026 53_[+1]_19 chr11:61472432-61472512 0.00026 38_[+1]_34 chr16:18603448-18603528 0.00026 36_[+1]_36 chr13:50699423-50699503 0.00036 59_[+1]_13 chr14:59654964-59655044 0.00036 69_[+1]_3 chr17:21454502-21454582 0.00036 68_[+1]_4 chr13:100633171-10063325 0.00036 8_[+1]_64 chr18:12302547-12302627 0.00047 4_[+1]_68 chr19:46144785-46144865 0.00047 10_[+1]_62 chr8:9008621-9008701 0.00047 11_[+1]_61 chr16:30670037-30670117 0.00047 32_[+1]_40 chr2:120770482-120770562 0.00047 27_[+1]_45 chr1:156471253-156471333 0.00047 [+1]_72 chr3:14272388-14272468 0.00047 46_[+1]_26 chr16:89359711-89359791 0.00047 38_[+1]_34 chr13:101261374-10126145 0.00047 52_[+1]_20 chr7:23762301-23762381 0.00047 44_[+1]_28 chr15:85177067-85177147 0.00047 55_[+1]_17 chr14:55852360-55852440 0.00047 21_[+1]_51 chr8:28514922-28515002 0.00047 35_[+1]_37 chr15:78931243-78931323 0.00047 53_[+1]_19 chr2:234475526-234475606 0.00056 37_[+1]_35 chr1:37980714-37980794 0.00056 56_[+1]_16 chr2:148601459-148601539 0.00056 8_[+1]_64 chr5:157376035-157376115 0.00056 8_[+1]_64 chr9:95571441-95571521 0.00056 32_[+1]_40 chr2:241887620-241887700 0.00056 30_[+1]_42 chrX:110924896-110924976 0.00056 45_[+1]_27 chr9:123836709-123836789 0.00056 4_[+1]_68 chr16:640441-640521 0.00056 53_[+1]_19 chr5:115420173-115420253 0.00056 11_[+1]_61 chr2:39002411-39002491 0.00056 19_[+1]_53 chr17:2310370-2310450 0.00056 34_[+1]_38 chr19:39177234-39177314 0.00063 6_[+1]_66 chr3:141206552-141206632 0.00063 19_[+1]_53 chr4:184328406-184328486 0.00063 42_[+1]_30 chr16:90039541-90039621 0.00063 25_[+1]_47 chr9:34523123-34523203 0.00063 36_[+1]_36 chr16:71518523-71518603 0.0007 29_[+1]_43 chr7:140188905-140188985 0.0007 46_[+1]_26 chr4:78739745-78739825 0.0007 13_[+1]_59 chr2:241075700-241075780 0.0007 20_[+1]_52 chr11:65339872-65339952 0.0007 54_[+1]_18 chr11:12133177-12133257 0.00076 13_[+1]_59 chr6:25153534-25153614 0.00076 24_[+1]_48 chr17:18128675-18128755 0.00076 29_[+1]_43 chr12:7342132-7342212 0.00076 52_[+1]_20 chr16:30406610-30406690 0.0009 67_[+1]_5 chr2:38603680-38603760 0.0009 6_[+1]_66 chrX:153402186-153402266 0.0009 36_[+1]_36 chr3:182896793-182896873 0.001 69_[+1]_3 chr8:28559765-28559845 0.001 69_[+1]_3 chr21:46294178-46294258 0.001 59_[+1]_13 chr8:125985444-125985524 0.001 53_[+1]_19 chr9:124030102-124030182 0.001 24_[+1]_48 chr11:35639696-35639776 0.001 5_[+1]_67 chr6:28785600-28785680 0.0012 31_[+1]_41 chr9:136243383-136243463 0.0012 8_[+1]_64 chr19:18705077-18705157 0.0012 11_[+1]_61 chr8:99058133-99058213 0.0012 10_[+1]_62 chr16:3239219-3239299 0.0012 50_[+1]_22 chr7:16685320-16685400 0.0012 53_[+1]_19 chr10:70715199-70715279 0.0012 53_[+1]_19 chr6:30434132-30434212 0.0012 35_[+1]_37 chr12:116714856-11671493 0.0012 39_[+1]_33 chr10:88854566-88854646 0.0012 38_[+1]_34 chr10:134298591-13429867 0.0012 [+1]_72 chr19:55988613-55988693 0.0013 16_[+1]_56 chr20:814677-814757 0.0013 36_[+1]_36 chr17:19281195-19281275 0.0013 29_[+1]_43 chr2:219264488-219264568 0.0013 3_[+1]_69 chr13:99660970-99661050 0.0013 61_[+1]_11 chrX:151081373-151081453 0.0015 38_[+1]_34 chr1:221458468-221458548 0.0016 71_[+1]_1 chr10:88853837-88853917 0.0016 9_[+1]_63 chr18:21290260-21290340 0.0016 51_[+1]_21 chr1:116512306-116512386 0.0016 69_[+1]_3 chr10:102295550-10229563 0.0017 8_[+1]_64 chr21:44494855-44494935 0.0017 54_[+1]_18 chr11:5962130-5962210 0.0017 47_[+1]_25 chr6:110012349-110012429 0.0018 40_[+1]_32 chr10:64576281-64576361 0.0018 40_[+1]_32 chr9:107730509-107730589 0.0019 41_[+1]_31 chr17:65989397-65989477 0.0019 66_[+1]_6 chr17:75457026-75457106 0.0019 32_[+1]_40 chr7:77428654-77428734 0.002 32_[+1]_40 chr19:7599082-7599162 0.002 22_[+1]_50 chr16:640644-640724 0.0021 62_[+1]_10 chr22:32026936-32027016 0.0022 15_[+1]_57 chr1:203598832-203598912 0.0023 49_[+1]_23 chr11:64513487-64513567 0.0023 72_[+1] chr9:73034076-73034156 0.0024 68_[+1]_4 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GGGCYCRS MEME-1 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF GGGCYCRS width=8 seqs=128 chr12:14720797-14720877 ( 27) GGGCCCAC 1 chr16:31008143-31008223 ( 13) GGGCCCAC 1 chr15:51914501-51914581 ( 42) GGGCCCAC 1 chr16:3055095-3055175 ( 65) GGGCCCAC 1 chr10:103336406-10333648 ( 31) GGGCCCAC 1 chr15:67187875-67187955 ( 48) GGGCCCAC 1 chr7:92384486-92384566 ( 47) GGGCCCAC 1 chr8:21999524-21999604 ( 23) GGGCCCAC 1 chr7:139529004-139529084 ( 53) GGGCCCAC 1 chr20:48610038-48610118 ( 46) GGGCCCAC 1 chr1:162660877-162660957 ( 37) GGGCCCAC 1 chr3:47545736-47545816 ( 34) GGGCCCAC 1 chr18:12946707-12946787 ( 12) GGGCCCAC 1 chr9:37411413-37411493 ( 11) GGGCCCAC 1 chr9:35115898-35115978 ( 33) GGGCCCAC 1 chr3:141752313-141752393 ( 22) GGGCCCAC 1 chr22:45645947-45646027 ( 39) GGGCCCAC 1 chr1:33565351-33565431 ( 54) GGGCCCAC 1 chr12:8171626-8171706 ( 43) GGGCCCAC 1 chr9:35732205-35732285 ( 13) GGGCCCGC 1 chr2:38751053-38751133 ( 41) GGGCCCGC 1 chr11:57103380-57103460 ( 14) GGGCCCGC 1 chr9:99983967-99984047 ( 70) GGGCCCGC 1 chr9:107690521-107690601 ( 69) GGGCCCGC 1 chr8:21911941-21912021 ( 20) GGGCCCGC 1 chr11:43963667-43963747 ( 3) GAGCCCAC 1 chr2:583290-583370 ( 47) GAGCCCAC 1 chr14:103671513-10367159 ( 16) GGGCCCAG 1 chr6:111926725-111926805 ( 26) GGGCTCGC 1 chrX:15873550-15873630 ( 60) GGGCTCGC 1 chr16:90015047-90015127 ( 37) GGGCTCGC 1 chr1:38157268-38157348 ( 49) GGGCTCGC 1 chr16:88589075-88589155 ( 51) GGGCCCAG 1 chr3:181412960-181413040 ( 50) GGGCTCGC 1 chr13:99852396-99852476 ( 30) GGGCTCGC 1 chr4:140477317-140477397 ( 58) GGGCTCGC 1 chr7:43152987-43153067 ( 54) GGGCTCGC 1 chr11:61472432-61472512 ( 39) GGGCTCGC 1 chr16:18603448-18603528 ( 37) GGGCCCAG 1 chr13:50699423-50699503 ( 60) GAGCCCGC 1 chr14:59654964-59655044 ( 70) GAGCCCGC 1 chr17:21454502-21454582 ( 69) GAGCCCGC 1 chr13:100633171-10063325 ( 9) GAGCCCGC 1 chr18:12302547-12302627 ( 5) GGCCCCAC 1 chr19:46144785-46144865 ( 11) GGCCCCAC 1 chr8:9008621-9008701 ( 12) GGGCCCGG 1 chr16:30670037-30670117 ( 33) GGGCCCGG 1 chr2:120770482-120770562 ( 28) GGGCCCGG 1 chr1:156471253-156471333 ( 1) GGGCCCGG 1 chr3:14272388-14272468 ( 47) GGCCCCAC 1 chr16:89359711-89359791 ( 39) GGCCCCAC 1 chr13:101261374-10126145 ( 53) GGCCCCAC 1 chr7:23762301-23762381 ( 45) GGCCCCAC 1 chr15:85177067-85177147 ( 56) GGGCCCGG 1 chr14:55852360-55852440 ( 22) GGCCCCAC 1 chr8:28514922-28515002 ( 36) GGCCCCAC 1 chr15:78931243-78931323 ( 54) GGCCCCAC 1 chr2:234475526-234475606 ( 38) GAGCTCGC 1 chr1:37980714-37980794 ( 57) GAGCTCGC 1 chr2:148601459-148601539 ( 9) GAGCTCGC 1 chr5:157376035-157376115 ( 9) GAGCCCAG 1 chr9:95571441-95571521 ( 33) GAGCCCAG 1 chr2:241887620-241887700 ( 31) GAGCCCAG 1 chrX:110924896-110924976 ( 46) GAGCTCGC 1 chr9:123836709-123836789 ( 5) GAGCCCAG 1 chr16:640441-640521 ( 54) GAGCTCGC 1 chr5:115420173-115420253 ( 12) GAGCTCGC 1 chr2:39002411-39002491 ( 20) GAGCTCGC 1 chr17:2310370-2310450 ( 35) GAGCCCAG 1 chr19:39177234-39177314 ( 7) GGCCTCAC 1 chr3:141206552-141206632 ( 20) GGGCTCGG 1 chr4:184328406-184328486 ( 43) GGGCTCGG 1 chr16:90039541-90039621 ( 26) GGGCTCGG 1 chr9:34523123-34523203 ( 37) GGGCTCGG 1 chr16:71518523-71518603 ( 30) AGGCTCAC 1 chr7:140188905-140188985 ( 47) GGTCCCAC 1 chr4:78739745-78739825 ( 14) GGTCCCAC 1 chr2:241075700-241075780 ( 21) AGGCTCAC 1 chr11:65339872-65339952 ( 55) GGTCCCAC 1 chr11:12133177-12133257 ( 14) GGCCCCGC 1 chr6:25153534-25153614 ( 25) GGCCCCGC 1 chr17:18128675-18128755 ( 30) GGCCCCGC 1 chr12:7342132-7342212 ( 53) GGCCCCGC 1 chr16:30406610-30406690 ( 68) AGGCCCGC 1 chr2:38603680-38603760 ( 7) GAGCCCGG 1 chrX:153402186-153402266 ( 37) AGGCCCGC 1 chr3:182896793-182896873 ( 70) AAGCCCAC 1 chr8:28559765-28559845 ( 70) GGCCTCGC 1 chr21:46294178-46294258 ( 60) GGCCCCAG 1 chr8:125985444-125985524 ( 54) GGCCCCAG 1 chr9:124030102-124030182 ( 25) GGCCCCAG 1 chr11:35639696-35639776 ( 6) GGCCCCAG 1 chr6:28785600-28785680 ( 32) GAGCTCGG 1 chr9:136243383-136243463 ( 9) AGGCCCAG 1 chr19:18705077-18705157 ( 12) AGGCTCGC 1 chr8:99058133-99058213 ( 11) GAGCTCGG 1 chr16:3239219-3239299 ( 51) AGGCTCGC 1 chr7:16685320-16685400 ( 54) GAGCTCGG 1 chr10:70715199-70715279 ( 54) GAGCTCGG 1 chr6:30434132-30434212 ( 36) GAGCTCGG 1 chr12:116714856-11671493 ( 40) AGGCTCGC 1 chr10:88854566-88854646 ( 39) GGTCCCGC 1 chr10:134298591-13429867 ( 1) AGGCTCGC 1 chr19:55988613-55988693 ( 17) GACCCCGC 1 chr20:814677-814757 ( 37) AGGCTCAG 1 chr17:19281195-19281275 ( 30) AGGCTCAG 1 chr2:219264488-219264568 ( 4) GGTCCCAG 1 chr13:99660970-99661050 ( 62) GGTCCCAG 1 chrX:151081373-151081453 ( 39) AAGCCCGC 1 chr1:221458468-221458548 ( 72) GACCCCAG 1 chr10:88853837-88853917 ( 10) AGGCCCGG 1 chr18:21290260-21290340 ( 52) AGCCCCAC 1 chr1:116512306-116512386 ( 70) AGCCCCAC 1 chr10:102295550-10229563 ( 9) GGCCTCGG 1 chr21:44494855-44494935 ( 55) AAGCTCGC 1 chr11:5962130-5962210 ( 48) AAGCTCGC 1 chr6:110012349-110012429 ( 41) GGTCCCGG 1 chr10:64576281-64576361 ( 41) GGTCCCGG 1 chr9:107730509-107730589 ( 42) GATCTCGC 1 chr17:65989397-65989477 ( 67) GATCTCGC 1 chr17:75457026-75457106 ( 33) GATCCCAG 1 chr7:77428654-77428734 ( 33) GGTCTCGG 1 chr19:7599082-7599162 ( 23) GACCCCGG 1 chr16:640644-640724 ( 63) GATCTCAG 1 chr22:32026936-32027016 ( 16) AGCCCCAG 1 chr1:203598832-203598912 ( 50) AGCCTCAG 1 chr11:64513487-64513567 ( 73) AGCCTCAG 1 chr9:73034076-73034156 ( 69) AGTCCCAG 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GGGCYCRS MEME-1 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 8.47348 E= 1.6e-014 -20 -1364 143 -1364 47 -1364 124 -1364 -1364 -44 113 -87 -1364 175 -1364 -1364 -1364 115 -1364 79 -1364 175 -1364 -1364 132 -1364 73 -1364 -1364 113 20 -1364 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GGGCYCRS MEME-1 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 128 E= 1.6e-014 0.171875 0.000000 0.828125 0.000000 0.273438 0.000000 0.726562 0.000000 0.000000 0.218750 0.671875 0.109375 0.000000 1.000000 0.000000 0.000000 0.000000 0.656250 0.000000 0.343750 0.000000 1.000000 0.000000 0.000000 0.492188 0.000000 0.507812 0.000000 0.000000 0.648438 0.351562 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GGGCYCRS MEME-1 regular expression -------------------------------------------------------------------------------- G[GA][GC]C[CT]C[GA][CG] -------------------------------------------------------------------------------- Time 5.04 secs. ******************************************************************************** ******************************************************************************** MOTIF CCTTTWAA MEME-2 width = 8 sites = 31 llr = 290 E-value = 9.5e-013 ******************************************************************************** -------------------------------------------------------------------------------- Motif CCTTTWAA MEME-2 Description -------------------------------------------------------------------------------- Simplified A 131::4aa pos.-specific C 871::::: probability G :::1:::: matrix T 1:89a6:: bits 2.3 * ** 2.1 * ** 1.9 ** ** 1.6 ** ** Relative 1.4 ***** Entropy 1.2 ****** (13.5 bits) 0.9 ******** 0.7 ******** 0.5 ******** 0.2 ******** 0.0 -------- Multilevel CCTTTTAA consensus A A sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCTTTWAA MEME-2 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr19:46010603-46010683 21 5.39e-06 GCAGAGTTGC CCTTTTAA GCGCCCTCCA chr9:73034076-73034156 1 5.39e-06 . CCTTTTAA AAAGTCTTCC chr2:219264488-219264568 59 5.39e-06 AAGCCGTTGC CCTTTTAA GGGGGAGCCT chr18:21290260-21290340 42 5.39e-06 CAGGTATTGC CCTTTTAA AAAGCCCCAC chr3:169850254-169850334 71 5.39e-06 tggtttgtgc ccttttaa ga chr10:88854566-88854646 56 5.39e-06 CGCGGGTTGC CCTTTTAA GCCGCAGCTT chr1:109783587-109783667 45 5.39e-06 CTGACATTGC CCTTTTAA GAGCCCTCTC chr6:117083096-117083176 24 5.39e-06 ACTGACTTGC CCTTTTAA GGAGATACTC chr17:75457026-75457106 58 5.39e-06 TACCCAGGGC CCTTTTAA AAATCTGTGG chr7:151649184-151649264 23 1.43e-05 aaagataagg cctttaaa gaggcagtta chr16:30670037-30670117 49 1.43e-05 GGAGGAGGCC CCTTTAAA TCTCCTTAAA chr11:18032806-18032886 12 1.43e-05 ggaaagaagg cctttaaa ggggcaatta chr15:46007304-46007384 48 1.43e-05 CCAATATTGC CCTTTAAA GTGGGCCCCT chr16:18603448-18603528 56 1.43e-05 ctaatgacct cattttaa cttcattgcc chr14:93930765-93930845 61 1.43e-05 gaaacggcct cattttaa cttaatcacc chr1:116512306-116512386 47 1.79e-05 GGGCAATGAC CATTTAAA GGAGCAATGC chr19:55988613-55988693 45 2.16e-05 CACGGATATC TCTTTTAA GGAGATGCTG chr7:98977986-98978066 65 3.29e-05 CTTCTTTGCC CCATTTAA GGGGTTTG chr15:52857868-52857948 67 4.46e-05 AACTCCCTCA ACTTTTAA CAATTG chr12:7342132-7342212 5 4.46e-05 CTTC CCCTTTAA GACTCACGGC chr22:32026936-32027016 55 4.46e-05 ACCCGAGGGC CCCTTTAA GAGGAAGGGC chr16:74637696-74637776 43 5.59e-05 TTTTTGTTTT TATTTAAA TAACTTGAAC chr1:156471253-156471333 25 5.59e-05 AGACGCCCAG CAATTTAA AGCGACAGCT chr2:54785578-54785658 16 5.59e-05 GGATTGGCCA TATTTAAA AGTTCTGAAG chr6:40106368-40106448 61 7.88e-05 gagttgtaag cccttaaa agggccagga chrX:44402060-44402140 73 7.88e-05 CTCTCCCTGG CACTTTAA chr11:65339872-65339952 72 7.88e-05 CAACCGTTGC CTTTTTAA G chr11:12133177-12133257 64 8.71e-05 GTGATTGTCG CCTGTTAA CTACAGTCT chr16:88589075-88589155 17 1.02e-04 CCGCCCGGGG AATTTAAA GTGGCCACTG chr4:184328406-184328486 73 1.25e-04 CAGCGCGGCG CCTGTAAA chr17:27396714-27396794 24 1.31e-04 GCCGCTGTAA TCATTAAA AGGGCAACAC -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCTTTWAA MEME-2 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr19:46010603-46010683 5.4e-06 20_[+2]_52 chr9:73034076-73034156 5.4e-06 [+2]_72 chr2:219264488-219264568 5.4e-06 58_[+2]_14 chr18:21290260-21290340 5.4e-06 41_[+2]_31 chr3:169850254-169850334 5.4e-06 70_[+2]_2 chr10:88854566-88854646 5.4e-06 55_[+2]_17 chr1:109783587-109783667 5.4e-06 44_[+2]_28 chr6:117083096-117083176 5.4e-06 23_[+2]_49 chr17:75457026-75457106 5.4e-06 57_[+2]_15 chr7:151649184-151649264 1.4e-05 22_[+2]_50 chr16:30670037-30670117 1.4e-05 48_[+2]_24 chr11:18032806-18032886 1.4e-05 11_[+2]_61 chr15:46007304-46007384 1.4e-05 47_[+2]_25 chr16:18603448-18603528 1.4e-05 55_[+2]_17 chr14:93930765-93930845 1.4e-05 60_[+2]_12 chr1:116512306-116512386 1.8e-05 46_[+2]_26 chr19:55988613-55988693 2.2e-05 44_[+2]_28 chr7:98977986-98978066 3.3e-05 64_[+2]_8 chr15:52857868-52857948 4.5e-05 66_[+2]_6 chr12:7342132-7342212 4.5e-05 4_[+2]_68 chr22:32026936-32027016 4.5e-05 54_[+2]_18 chr16:74637696-74637776 5.6e-05 42_[+2]_30 chr1:156471253-156471333 5.6e-05 24_[+2]_48 chr2:54785578-54785658 5.6e-05 15_[+2]_57 chr6:40106368-40106448 7.9e-05 60_[+2]_12 chrX:44402060-44402140 7.9e-05 72_[+2] chr11:65339872-65339952 7.9e-05 71_[+2]_1 chr11:12133177-12133257 8.7e-05 63_[+2]_9 chr16:88589075-88589155 0.0001 16_[+2]_56 chr4:184328406-184328486 0.00012 72_[+2] chr17:27396714-27396794 0.00013 23_[+2]_49 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCTTTWAA MEME-2 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF CCTTTWAA width=8 seqs=31 chr19:46010603-46010683 ( 21) CCTTTTAA 1 chr9:73034076-73034156 ( 1) CCTTTTAA 1 chr2:219264488-219264568 ( 59) CCTTTTAA 1 chr18:21290260-21290340 ( 42) CCTTTTAA 1 chr3:169850254-169850334 ( 71) CCTTTTAA 1 chr10:88854566-88854646 ( 56) CCTTTTAA 1 chr1:109783587-109783667 ( 45) CCTTTTAA 1 chr6:117083096-117083176 ( 24) CCTTTTAA 1 chr17:75457026-75457106 ( 58) CCTTTTAA 1 chr7:151649184-151649264 ( 23) CCTTTAAA 1 chr16:30670037-30670117 ( 49) CCTTTAAA 1 chr11:18032806-18032886 ( 12) CCTTTAAA 1 chr15:46007304-46007384 ( 48) CCTTTAAA 1 chr16:18603448-18603528 ( 56) CATTTTAA 1 chr14:93930765-93930845 ( 61) CATTTTAA 1 chr1:116512306-116512386 ( 47) CATTTAAA 1 chr19:55988613-55988693 ( 45) TCTTTTAA 1 chr7:98977986-98978066 ( 65) CCATTTAA 1 chr15:52857868-52857948 ( 67) ACTTTTAA 1 chr12:7342132-7342212 ( 5) CCCTTTAA 1 chr22:32026936-32027016 ( 55) CCCTTTAA 1 chr16:74637696-74637776 ( 43) TATTTAAA 1 chr1:156471253-156471333 ( 25) CAATTTAA 1 chr2:54785578-54785658 ( 16) TATTTAAA 1 chr6:40106368-40106448 ( 61) CCCTTAAA 1 chrX:44402060-44402140 ( 73) CACTTTAA 1 chr11:65339872-65339952 ( 72) CTTTTTAA 1 chr11:12133177-12133257 ( 64) CCTGTTAA 1 chr16:88589075-88589155 ( 17) AATTTAAA 1 chr4:184328406-184328486 ( 73) CCTGTAAA 1 chr17:27396714-27396794 ( 24) TCATTAAA 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCTTTWAA MEME-2 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 10.4993 E= 9.5e-013 -161 144 -1160 -63 38 126 -1160 -262 -103 -120 -1160 196 -1160 -1160 -225 223 -1160 -1160 -1160 233 84 -1160 -1160 169 234 -1160 -1160 -1160 234 -1160 -1160 -1160 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCTTTWAA MEME-2 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 31 E= 9.5e-013 0.064516 0.806452 0.000000 0.129032 0.258065 0.709677 0.000000 0.032258 0.096774 0.129032 0.000000 0.774194 0.000000 0.000000 0.064516 0.935484 0.000000 0.000000 0.000000 1.000000 0.354839 0.000000 0.000000 0.645161 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCTTTWAA MEME-2 regular expression -------------------------------------------------------------------------------- C[CA]TTT[TA]AA -------------------------------------------------------------------------------- Time 8.65 secs. ******************************************************************************** ******************************************************************************** MOTIF TTAAADGG MEME-3 width = 8 sites = 11 llr = 115 E-value = 1.5e+002 ******************************************************************************** -------------------------------------------------------------------------------- Motif TTAAADGG MEME-3 Description -------------------------------------------------------------------------------- Simplified A ::aaa5:3 pos.-specific C :::::::: probability G :::::3a7 matrix T aa:::3:: bits 2.3 ***** 2.1 ***** 1.9 ***** 1.6 ***** * Relative 1.4 ***** * Entropy 1.2 ***** * (15.0 bits) 0.9 ***** ** 0.7 ******** 0.5 ******** 0.2 ******** 0.0 -------- Multilevel TTAAAAGG consensus G A sequence T -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTAAADGG MEME-3 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr2:219261202-219261282 73 5.74e-06 TTCCTCTTTC TTAAAAGG chrX:120181426-120181506 10 5.74e-06 AGCTGCGGC TTAAAAGG GCAACCCGCG chr16:18603448-18603528 9 5.74e-06 tcctcttc ttaaaagg accccagtca chr14:93930765-93930845 11 5.74e-06 taatctcctc ttaaaagg acagcagtca chr17:75457026-75457106 6 5.74e-06 TTTAT TTAAAAGG GTCATTTAGT chr19:55988613-55988693 9 1.52e-05 TCTTCTTG TTAAATGG GACCCCGCTC chr16:30670037-30670117 62 2.41e-05 TTAAATCTCC TTAAAGGG GTGGCCACTG chr1:116512306-116512386 31 2.41e-05 GGGCAGAATC TTAAAGGG GCAATGACCA chr11:18032806-18032886 33 2.78e-05 gcaattaagg ttaaatga ggtcataagg chr3:169850254-169850334 25 2.78e-05 gtaacaaagg ttaaatga ggtcataggg chr15:67187875-67187955 60 3.36e-05 gcccacaaga ttaaagga gccagttgat -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTAAADGG MEME-3 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr2:219261202-219261282 5.7e-06 72_[+3] chrX:120181426-120181506 5.7e-06 9_[+3]_63 chr16:18603448-18603528 5.7e-06 8_[+3]_64 chr14:93930765-93930845 5.7e-06 10_[+3]_62 chr17:75457026-75457106 5.7e-06 5_[+3]_67 chr19:55988613-55988693 1.5e-05 8_[+3]_64 chr16:30670037-30670117 2.4e-05 61_[+3]_11 chr1:116512306-116512386 2.4e-05 30_[+3]_42 chr11:18032806-18032886 2.8e-05 32_[+3]_40 chr3:169850254-169850334 2.8e-05 24_[+3]_48 chr15:67187875-67187955 3.4e-05 59_[+3]_13 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTAAADGG MEME-3 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF TTAAADGG width=8 seqs=11 chr2:219261202-219261282 ( 73) TTAAAAGG 1 chrX:120181426-120181506 ( 10) TTAAAAGG 1 chr16:18603448-18603528 ( 9) TTAAAAGG 1 chr14:93930765-93930845 ( 11) TTAAAAGG 1 chr17:75457026-75457106 ( 6) TTAAAAGG 1 chr19:55988613-55988693 ( 9) TTAAATGG 1 chr16:30670037-30670117 ( 62) TTAAAGGG 1 chr1:116512306-116512386 ( 31) TTAAAGGG 1 chr11:18032806-18032886 ( 33) TTAAATGA 1 chr3:169850254-169850334 ( 25) TTAAATGA 1 chr15:67187875-67187955 ( 60) TTAAAGGA 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTAAADGG MEME-3 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 11.0506 E= 1.5e+002 -1010 -1010 -1010 233 -1010 -1010 -1010 233 234 -1010 -1010 -1010 234 -1010 -1010 -1010 234 -1010 -1010 -1010 120 -1010 -17 45 -1010 -1010 170 -1010 46 -1010 125 -1010 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTAAADGG MEME-3 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 11 E= 1.5e+002 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.454545 0.000000 0.272727 0.272727 0.000000 0.000000 1.000000 0.000000 0.272727 0.000000 0.727273 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTAAADGG MEME-3 regular expression -------------------------------------------------------------------------------- TTAAA[AGT]G[GA] -------------------------------------------------------------------------------- Time 12.23 secs. ******************************************************************************** ******************************************************************************** MOTIF RGAGGAAR MEME-4 width = 8 sites = 26 llr = 223 E-value = 6.9e+002 ******************************************************************************** -------------------------------------------------------------------------------- Motif RGAGGAAR MEME-4 Description -------------------------------------------------------------------------------- Simplified A 4:a1:7a6 pos.-specific C :1:::::: probability G 69:9a3:4 matrix T :::::::: bits 2.3 * * 2.1 * * 1.9 * * 1.6 * * * Relative 1.4 ***** Entropy 1.2 ******* (12.4 bits) 0.9 ******** 0.7 ******** 0.5 ******** 0.2 ******** 0.0 -------- Multilevel GGAGGAAA consensus A G G sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif RGAGGAAR MEME-4 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr16:31008143-31008223 57 8.81e-06 CCCCCTCCAG AGAGGAAA TGCCTGGAAG chr7:72299052-72299132 2 8.81e-06 A AGAGGAAA GGAGTGGGGA chr2:191184625-191184705 30 2.25e-05 AACGACGCCT GGAGGAAA TAGTTGAGGG chr2:38751053-38751133 20 2.25e-05 GGGGCAGCCC GGAGGAAA ACGCATGGAT chr6:149068091-149068171 3 2.25e-05 aa ggagGAAA ACCCCTGTCA chr4:2390322-2390402 5 3.61e-05 TTTC AGAGGAAG GAACATAGGA chr14:74769721-74769801 1 3.61e-05 . AGAGGAAG GTGCGGGAGA chr13:50699423-50699503 29 5.73e-05 CAACGGCGGA GGAGGAAG ACCCCCGTTC chr5:172878211-172878291 32 5.73e-05 CTATTTCAGT GGAGGAAG GCCTGTTAGG chr2:128643674-128643754 18 5.73e-05 GTGAGGTAAT GGAGGAAG AATGTAGGGA chr10:81586248-81586328 14 5.73e-05 GTGAGGTAAT GGAGGAAG AATGTAGGGA chr10:88854566-88854646 31 5.73e-05 CCGCGACTAG GGAGGAAG GGTCCCGCGC chr10:89102289-89102369 15 5.73e-05 GTGAGATAAT GGAGGAAG AATGTAGGGA chr17:41985000-41985080 12 5.73e-05 GGCACAACTC GGAGGAAG TAGTCTTTCC chr2:583290-583370 1 7.09e-05 . AGAGGGAA CAAGGCCGTG chr12:8171626-8171706 12 7.09e-05 GCGACCGGGG AGAGGGAA CCCTTTACGG chr9:123836709-123836789 60 9.21e-05 TTCGGTCCCT GGAGGGAA TTCGCTTTAG chr1:109791985-109792065 43 9.21e-05 GGGTCCTGCT GGAGGGAA TCCTGGCGCT chr11:125011891-12501197 63 9.21e-05 TAGAAAGAGG GGAGGGAA GGGCTCTGTG chr2:70484571-70484651 65 9.21e-05 GAGGAGCGAC GGAGGGAA CAGAAGAG chr1:156095891-156095971 38 1.01e-04 TTCCTGGGAG ACAGGAAA TGCCCAGGGG chr7:92384486-92384566 25 1.01e-04 CTCCTTGCTA ACAGGAAA GACACATTGC chr3:141206552-141206632 64 1.19e-04 GCCCTGAGCT GCAGGAAA CGGGCCGCC chr17:43227050-43227130 28 1.19e-04 ACCTGGGAAG AGAAGAAA AAGTTCGACG chr22:45645947-45646027 71 1.19e-04 TATTGATGAA AGAAGAAA AT chr5:173312734-173312814 9 1.49e-04 gtgtagac agagggag gtgattggat -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif RGAGGAAR MEME-4 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr16:31008143-31008223 8.8e-06 56_[+4]_16 chr7:72299052-72299132 8.8e-06 1_[+4]_71 chr2:191184625-191184705 2.2e-05 29_[+4]_43 chr2:38751053-38751133 2.2e-05 19_[+4]_53 chr6:149068091-149068171 2.2e-05 2_[+4]_70 chr4:2390322-2390402 3.6e-05 4_[+4]_68 chr14:74769721-74769801 3.6e-05 [+4]_72 chr13:50699423-50699503 5.7e-05 28_[+4]_44 chr5:172878211-172878291 5.7e-05 31_[+4]_41 chr2:128643674-128643754 5.7e-05 17_[+4]_55 chr10:81586248-81586328 5.7e-05 13_[+4]_59 chr10:88854566-88854646 5.7e-05 30_[+4]_42 chr10:89102289-89102369 5.7e-05 14_[+4]_58 chr17:41985000-41985080 5.7e-05 11_[+4]_61 chr2:583290-583370 7.1e-05 [+4]_72 chr12:8171626-8171706 7.1e-05 11_[+4]_61 chr9:123836709-123836789 9.2e-05 59_[+4]_13 chr1:109791985-109792065 9.2e-05 42_[+4]_30 chr11:125011891-12501197 9.2e-05 62_[+4]_10 chr2:70484571-70484651 9.2e-05 64_[+4]_8 chr1:156095891-156095971 0.0001 37_[+4]_35 chr7:92384486-92384566 0.0001 24_[+4]_48 chr3:141206552-141206632 0.00012 63_[+4]_9 chr17:43227050-43227130 0.00012 27_[+4]_45 chr22:45645947-45646027 0.00012 70_[+4]_2 chr5:173312734-173312814 0.00015 8_[+4]_64 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif RGAGGAAR MEME-4 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF RGAGGAAR width=8 seqs=26 chr16:31008143-31008223 ( 57) AGAGGAAA 1 chr7:72299052-72299132 ( 2) AGAGGAAA 1 chr2:191184625-191184705 ( 30) GGAGGAAA 1 chr2:38751053-38751133 ( 20) GGAGGAAA 1 chr6:149068091-149068171 ( 3) GGAGGAAA 1 chr4:2390322-2390402 ( 5) AGAGGAAG 1 chr14:74769721-74769801 ( 1) AGAGGAAG 1 chr13:50699423-50699503 ( 29) GGAGGAAG 1 chr5:172878211-172878291 ( 32) GGAGGAAG 1 chr2:128643674-128643754 ( 18) GGAGGAAG 1 chr10:81586248-81586328 ( 14) GGAGGAAG 1 chr10:88854566-88854646 ( 31) GGAGGAAG 1 chr10:89102289-89102369 ( 15) GGAGGAAG 1 chr17:41985000-41985080 ( 12) GGAGGAAG 1 chr2:583290-583370 ( 1) AGAGGGAA 1 chr12:8171626-8171706 ( 12) AGAGGGAA 1 chr9:123836709-123836789 ( 60) GGAGGGAA 1 chr1:109791985-109792065 ( 43) GGAGGGAA 1 chr11:125011891-12501197 ( 63) GGAGGGAA 1 chr2:70484571-70484651 ( 65) GGAGGGAA 1 chr1:156095891-156095971 ( 38) ACAGGAAA 1 chr7:92384486-92384566 ( 25) ACAGGAAA 1 chr3:141206552-141206632 ( 64) GCAGGAAA 1 chr17:43227050-43227130 ( 28) AGAAGAAA 1 chr22:45645947-45646027 ( 71) AGAAGAAA 1 chr5:173312734-173312814 ( 9) AGAGGGAG 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif RGAGGAAR MEME-4 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 9.98426 E= 6.9e+002 110 -1134 91 -1134 -1134 -136 153 -1134 234 -1134 -1134 -1134 -136 -1134 159 -1134 -1134 -1134 171 -1134 189 -1134 -19 -1134 234 -1134 -1134 -1134 164 -1134 33 -1134 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif RGAGGAAR MEME-4 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 26 E= 6.9e+002 0.423077 0.000000 0.576923 0.000000 0.000000 0.115385 0.884615 0.000000 1.000000 0.000000 0.000000 0.000000 0.076923 0.000000 0.923077 0.000000 0.000000 0.000000 1.000000 0.000000 0.730769 0.000000 0.269231 0.000000 1.000000 0.000000 0.000000 0.000000 0.615385 0.000000 0.384615 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif RGAGGAAR MEME-4 regular expression -------------------------------------------------------------------------------- [GA]GAGG[AG]A[AG] -------------------------------------------------------------------------------- Time 15.78 secs. ******************************************************************************** ******************************************************************************** MOTIF TTTTCAAA MEME-5 width = 8 sites = 4 llr = 50 E-value = 1.6e+003 ******************************************************************************** -------------------------------------------------------------------------------- Motif TTTTCAAA MEME-5 Description -------------------------------------------------------------------------------- Simplified A :::::aaa pos.-specific C ::::a::: probability G :::::::: matrix T aaaa:::: bits 2.3 **** *** 2.1 **** *** 1.9 ******** 1.6 ******** Relative 1.4 ******** Entropy 1.2 ******** (18.1 bits) 0.9 ******** 0.7 ******** 0.5 ******** 0.2 ******** 0.0 -------- Multilevel TTTTCAAA consensus sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTTTCAAA MEME-5 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr11:19734060-19734140 62 3.60e-06 GAAAGGGCAT TTTTCAAA AGAAGGGTTT chr6:64308750-64308830 33 3.60e-06 tttcattcac ttttcaaa tctcatacac chr7:140188905-140188985 12 3.60e-06 ccacacttga ttttcaaa ggccttacat chr18:21290260-21290340 16 3.60e-06 GCAAGTTTGA TTTTCAAA AGTATTGTCA -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTTTCAAA MEME-5 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr11:19734060-19734140 3.6e-06 61_[+5]_11 chr6:64308750-64308830 3.6e-06 32_[+5]_40 chr7:140188905-140188985 3.6e-06 11_[+5]_61 chr18:21290260-21290340 3.6e-06 15_[+5]_57 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTTTCAAA MEME-5 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF TTTTCAAA width=8 seqs=4 chr11:19734060-19734140 ( 62) TTTTCAAA 1 chr6:64308750-64308830 ( 33) TTTTCAAA 1 chr7:140188905-140188985 ( 12) TTTTCAAA 1 chr18:21290260-21290340 ( 16) TTTTCAAA 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTTTCAAA MEME-5 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 12.1553 E= 1.6e+003 -865 -865 -865 232 -865 -865 -865 232 -865 -865 -865 232 -865 -865 -865 232 -865 175 -865 -865 234 -865 -865 -865 234 -865 -865 -865 234 -865 -865 -865 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTTTCAAA MEME-5 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 4 E= 1.6e+003 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTTTCAAA MEME-5 regular expression -------------------------------------------------------------------------------- TTTTCAAA -------------------------------------------------------------------------------- Time 19.31 secs. ******************************************************************************** ******************************************************************************** SUMMARY OF MOTIFS ******************************************************************************** -------------------------------------------------------------------------------- Combined block diagrams: non-overlapping sites with p-value < 0.0001 -------------------------------------------------------------------------------- SEQUENCE NAME COMBINED P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr17:75457026-75457106 3.04e-07 5_[+3(5.74e-06)]_44_[+2(5.39e-06)]_\ 15 chr11:35639696-35639776 8.50e-01 80 chr12:8171626-8171706 8.01e-04 11_[+4(7.09e-05)]_23_[+1(4.40e-05)]_\ 30 chr15:78931243-78931323 1.45e-01 80 chr11:65339872-65339952 3.84e-03 71_[+2(7.88e-05)]_1 chr6:117083096-117083176 1.75e-03 6_[+2(5.39e-06)]_9_[+2(5.39e-06)]_\ 49 chr17:41985000-41985080 2.37e-01 11_[+4(5.73e-05)]_61 chr14:93930765-93930845 1.17e-05 10_[+3(5.74e-06)]_42_[+2(1.43e-05)]_\ 12 chr1:33565351-33565431 3.23e-04 53_[+1(4.40e-05)]_19 chr19:44031511-44031591 7.80e-02 80 chr17:4959009-4959089 5.85e-01 80 chr16:18603448-18603528 2.41e-06 8_[+3(5.74e-06)]_39_[+2(1.43e-05)]_\ 17 chr1:116512306-116512386 5.42e-05 30_[+3(2.41e-05)]_8_[+2(1.79e-05)]_\ 26 chr22:45645947-45646027 3.15e-03 38_[+1(4.40e-05)]_34 chr3:141752313-141752393 7.49e-03 21_[+1(4.40e-05)]_51 chr9:35115898-35115978 2.30e-01 32_[+1(4.40e-05)]_40 chr12:114196488-11419656 9.22e-02 80 chrX:120181426-120181506 1.27e-02 9_[+3(5.74e-06)]_63 chr9:37411413-37411493 1.86e-01 10_[+1(4.40e-05)]_62 chr10:134298591-13429867 1.46e-02 80 chr14:102512774-10251285 3.73e-01 4_[+4(9.21e-05)]_29_[+4(9.21e-05)]_\ 31 chr15:46007304-46007384 3.49e-04 47_[+2(1.43e-05)]_25 chr1:230907701-230907781 4.53e-01 80 chr11:61472432-61472512 6.28e-01 80 chr1:109783587-109783667 6.49e-04 44_[+2(5.39e-06)]_28 chr16:23711920-23712000 9.14e-01 80 chr18:12946707-12946787 7.81e-04 11_[+1(4.40e-05)]_61 chr4:159969338-159969418 3.83e-01 80 chr17:4901027-4901107 9.82e-01 80 chr10:82075978-82076058 2.53e-01 80 chr1:175190895-175190975 5.89e-01 80 chr22:32026936-32027016 3.46e-05 61_[+4(3.61e-05)]_11 chr3:47545736-47545816 2.01e-01 33_[+1(4.40e-05)]_39 chr10:89102289-89102369 1.32e-01 14_[+4(5.73e-05)]_58 chr2:70484571-70484651 5.37e-02 64_[+4(9.21e-05)]_8 chr15:102286575-10228665 4.76e-01 80 chr7:43152987-43153067 4.60e-01 80 chr10:88854566-88854646 4.85e-05 30_[+4(5.73e-05)]_17_[+2(5.39e-06)]_\ 17 chrX:153402186-153402266 2.07e-01 80 chr19:51109377-51109457 8.01e-02 80 chr2:583290-583370 1.41e-02 [+4(7.09e-05)]_72 chr14:101012893-10101297 9.66e-01 80 chr8:21911941-21912021 3.20e-01 80 chr17:1466234-1466314 9.56e-01 80 chr17:2310370-2310450 3.32e-01 80 chr9:107690521-107690601 1.04e-01 80 chr9:38026383-38026463 5.23e-01 80 chr1:162660877-162660957 3.30e-02 36_[+1(4.40e-05)]_36 chr11:125011891-12501197 8.26e-04 62_[+4(9.21e-05)]_10 chr15:84841379-84841459 7.54e-01 80 chr2:39002411-39002491 8.78e-02 80 chr11:43963667-43963747 1.65e-01 80 chr1:118149743-118149823 7.94e-01 80 chr20:48610038-48610118 8.46e-02 45_[+1(4.40e-05)]_27 chr7:139529004-139529084 1.41e-03 52_[+1(4.40e-05)]_20 chr4:140477317-140477397 1.82e-01 80 chr13:99660970-99661050 6.33e-01 80 chr1:109791985-109792065 3.31e-01 42_[+4(9.21e-05)]_30 chr8:21999524-21999604 1.26e-01 22_[+1(4.40e-05)]_50 chr10:81586248-81586328 1.32e-01 13_[+4(5.73e-05)]_59 chr3:169850254-169850334 9.97e-06 24_[+3(2.78e-05)]_38_[+2(5.39e-06)]_\ 2 chr12:133065736-13306581 5.49e-01 80 chr9:32384796-32384876 8.47e-01 80 chrX:139139338-139139418 9.09e-01 80 chr10:64576281-64576361 9.16e-01 80 chr2:54785578-54785658 8.77e-04 18_[+3(5.14e-05)]_54 chr13:100633171-10063325 6.79e-01 80 chr8:28514922-28515002 3.40e-01 80 chr7:44622313-44622393 9.89e-01 80 chr9:99983967-99984047 2.54e-01 80 chr13:99852396-99852476 4.07e-01 80 chr11:64513487-64513567 9.44e-01 80 chr10:96162063-96162143 9.63e-01 80 chr14:75229871-75229951 1.66e-02 80 chr17:21454502-21454582 1.34e-01 80 chr5:115420173-115420253 9.89e-02 80 chr11:5962130-5962210 8.00e-02 80 chr11:120302503-12030258 5.96e-01 80 chr14:55852360-55852440 3.12e-01 80 chr14:74769721-74769801 3.66e-03 [+4(3.61e-05)]_72 chr4:2390322-2390402 8.52e-02 4_[+4(3.61e-05)]_68 chr17:65989397-65989477 5.30e-01 80 chr3:44727185-44727265 1.91e-01 80 chr12:116714856-11671493 5.52e-01 80 chr7:92384486-92384566 1.93e-03 46_[+1(4.40e-05)]_26 chr16:640441-640521 4.85e-01 80 chr3:181412960-181413040 3.50e-01 80 chr9:123836709-123836789 2.38e-02 59_[+4(9.21e-05)]_13 chr18:21290260-21290340 7.59e-07 15_[+5(3.60e-06)]_18_[+2(5.39e-06)]_\ 31 chr9:124030102-124030182 8.11e-01 80 chr19:46283893-46283973 4.28e-01 53_[+4(9.21e-05)]_19 chr7:98977986-98978066 4.13e-03 64_[+2(3.29e-05)]_8 chr8:102904139-102904219 9.43e-02 80 chr2:219264488-219264568 3.63e-04 58_[+2(5.39e-06)]_14 chr2:219261202-219261282 8.36e-05 72_[+3(5.74e-06)] chrX:110924896-110924976 7.24e-01 80 chr20:42073783-42073863 9.29e-01 80 chr17:43227050-43227130 6.83e-02 80 chr8:144853287-144853367 7.19e-01 80 chr15:85177067-85177147 7.01e-01 80 chr11:120039828-12003990 7.15e-01 80 chr2:128643674-128643754 1.32e-01 17_[+4(5.73e-05)]_55 chr3:121264854-121264934 2.87e-01 80 chr2:241887620-241887700 3.94e-01 80 chr1:46665164-46665244 4.73e-01 80 chr6:30434132-30434212 5.92e-01 80 chr18:12946910-12946990 9.86e-01 80 chr17:21935018-21935098 9.95e-01 80 chr2:241075700-241075780 7.90e-01 80 chr10:70715199-70715279 5.15e-02 80 chr6:110012349-110012429 8.96e-01 80 chr15:67187875-67187955 6.82e-04 47_[+1(4.40e-05)]_4_[+3(3.36e-05)]_\ 13 chr3:186545502-186545582 3.55e-01 80 chr9:95571441-95571521 6.90e-01 80 chr7:16685320-16685400 7.49e-01 80 chr1:8377962-8378042 9.81e-01 80 chr10:103336406-10333648 7.21e-03 30_[+1(4.40e-05)]_42 chr2:38603680-38603760 3.35e-01 80 chr4:78739745-78739825 5.95e-01 80 chr16:3239219-3239299 1.76e-01 80 chr8:99058133-99058213 5.72e-01 80 chr19:18315791-18315871 1.09e-01 80 chrX:18443780-18443860 8.18e-01 80 chr7:23762301-23762381 1.03e-01 80 chr12:65073277-65073357 3.68e-01 80 chrX:151081373-151081453 2.23e-02 32_[+4(9.21e-05)]_40 chr17:41984022-41984102 9.59e-01 80 chr13:101261374-10126145 2.41e-01 80 chr12:7342132-7342212 1.69e-03 4_[+2(4.46e-05)]_68 chr15:52857868-52857948 1.40e-02 66_[+2(4.46e-05)]_6 chr1:204380090-204380170 8.33e-01 80 chr17:19281195-19281275 6.35e-01 80 chr16:3055095-3055175 5.49e-02 64_[+1(4.40e-05)]_8 chr12:131892044-13189212 9.66e-01 80 chr6:35226663-35226743 1.09e-01 80 chr5:172878211-172878291 3.47e-02 31_[+4(5.73e-05)]_41 chr8:125985444-125985524 3.64e-01 80 chr7:140188905-140188985 2.06e-05 11_[+5(3.60e-06)]_61 chr9:34523123-34523203 3.21e-01 80 chr7:5462569-5462649 9.01e-01 80 chr16:640644-640724 5.70e-01 80 chr12:49297813-49297893 6.67e-01 80 chr15:51914501-51914581 2.49e-02 41_[+1(4.40e-05)]_31 chr21:44494855-44494935 2.31e-01 80 chr1:27929822-27929902 5.17e-01 80 chr16:89359711-89359791 1.34e-01 80 chr17:27396714-27396794 1.56e-03 26_[+3(5.74e-06)]_46 chr6:28411285-28411365 3.48e-01 80 chr16:88589075-88589155 4.44e-04 80 chr9:107730509-107730589 2.53e-01 80 chr14:20774101-20774181 5.99e-01 80 chr5:173312734-173312814 2.63e-01 80 chr9:73034076-73034156 1.64e-06 [+2(5.39e-06)]_72 chr1:203598832-203598912 5.05e-01 80 chr12:50478851-50478931 8.46e-01 80 chr5:157376035-157376115 1.53e-02 80 chrX:44402060-44402140 2.59e-01 72_[+2(7.88e-05)] chr16:14927439-14927519 6.37e-01 80 chr3:14443837-14443917 8.58e-01 80 chr16:90039541-90039621 4.74e-01 80 chr11:122526714-12252679 9.96e-01 80 chr6:149068091-149068171 2.70e-03 2_[+4(2.25e-05)]_70 chr3:14272388-14272468 6.30e-01 80 chr16:89767315-89767395 9.96e-01 80 chr2:205409946-205410026 3.98e-01 80 chr16:30406610-30406690 8.52e-01 80 chr14:59654964-59655044 8.41e-02 80 chr1:38157268-38157348 3.89e-01 80 chr1:22014020-22014100 1.59e-01 80 chr19:605287-605367 1.12e-01 80 chr1:156471253-156471333 2.30e-03 24_[+2(5.59e-05)]_48 chr16:90015047-90015127 5.71e-01 80 chr17:18128675-18128755 6.94e-01 80 chr17:55498171-55498251 6.28e-01 80 chrX:15873550-15873630 5.62e-01 80 chr1:231176211-231176291 8.84e-01 80 chr20:814677-814757 2.15e-02 80 chr6:111926725-111926805 1.48e-02 80 chr12:117197653-11719773 7.40e-01 80 chr4:184328406-184328486 7.19e-02 80 chr16:71518523-71518603 6.18e-01 80 chr2:219524259-219524339 9.72e-01 80 chr2:148601459-148601539 7.51e-01 80 chr21:46294178-46294258 4.15e-02 80 chr10:88853837-88853917 1.53e-02 80 chr19:7599082-7599162 7.64e-01 80 chr17:7210201-7210281 1.59e-01 80 chr11:57103380-57103460 1.59e-01 80 chr11:18032806-18032886 3.95e-04 11_[+2(1.43e-05)]_13_[+3(2.78e-05)]_\ 40 chr2:231921290-231921370 9.61e-01 80 chr14:103671513-10367159 3.14e-01 80 chr3:141206552-141206632 1.14e-02 80 chr5:104725142-104725222 1.81e-01 80 chr2:38751053-38751133 7.07e-03 19_[+4(2.25e-05)]_53 chr19:55988613-55988693 1.11e-05 8_[+3(1.52e-05)]_28_[+2(2.16e-05)]_\ 28 chr2:131099556-131099636 9.96e-01 80 chr8:28559765-28559845 7.91e-01 80 chr9:35732205-35732285 4.55e-02 80 chr7:72299052-72299132 2.70e-03 1_[+4(8.81e-06)]_71 chr19:18705077-18705157 4.24e-01 80 chr1:227915926-227916006 7.09e-01 80 chr9:136243383-136243463 5.29e-01 80 chr2:120770482-120770562 6.87e-01 80 chr3:128598627-128598707 4.81e-01 80 chr13:50699423-50699503 6.42e-03 28_[+4(5.73e-05)]_44 chr16:30670037-30670117 1.74e-05 48_[+2(1.43e-05)]_5_[+3(2.41e-05)]_\ 11 chr20:62886863-62886943 9.51e-01 80 chr16:31008143-31008223 1.23e-03 12_[+1(4.40e-05)]_36_[+4(8.81e-06)]_\ 16 chr1:28696637-28696717 9.55e-01 80 chr1:231175544-231175624 8.69e-01 80 chr16:74637696-74637776 4.97e-03 42_[+2(5.59e-05)]_30 chr5:137558680-137558760 1.64e-01 80 chr12:6643341-6643421 9.72e-01 80 chr19:39177234-39177314 5.97e-01 80 chr3:182896793-182896873 3.67e-01 80 chr3:182896589-182896669 8.31e-01 80 chr12:46123710-46123790 9.21e-01 80 chr17:28705706-28705786 4.44e-01 80 chr17:58042315-58042395 2.93e-01 80 chr7:151649184-151649264 6.24e-05 22_[+2(1.43e-05)]_12_[+3(6.43e-05)]_\ 30 chr6:28785600-28785680 3.55e-01 80 chr19:42829687-42829767 1.00e+00 80 chr14:24685256-24685336 8.86e-01 80 chr1:162035381-162035461 2.37e-01 80 chr6:25153534-25153614 1.17e-02 80 chr11:14112106-14112186 6.98e-01 80 chr1:10057-10137 1.00e+00 80 chr3:150421886-150421966 6.95e-01 80 chr2:129494276-129494356 9.93e-01 80 chr17:26646364-26646444 9.46e-01 80 chr8:9008621-9008701 6.56e-01 80 chr6:40106368-40106448 4.75e-04 63_[+3(5.74e-06)]_9 chr11:12133177-12133257 7.16e-02 63_[+2(8.71e-05)]_9 chr7:77428654-77428734 5.95e-01 80 chr17:7819533-7819613 5.10e-01 80 chr10:102295550-10229563 7.56e-01 80 chr1:28995031-28995111 1.31e-01 80 chr19:46010603-46010683 9.51e-03 20_[+2(5.39e-06)]_36_[+2(4.46e-05)]_\ 8 chr6:64308750-64308830 7.12e-03 32_[+5(3.60e-06)]_40 chr1:37980714-37980794 5.58e-02 80 chr12:14720797-14720877 6.84e-02 26_[+1(4.40e-05)]_46 chr2:234475526-234475606 5.87e-02 80 chr19:46144785-46144865 5.48e-01 80 chr17:66509218-66509298 5.21e-01 80 chr11:19734060-19734140 3.45e-04 61_[+5(3.60e-06)]_11 chr1:221458468-221458548 4.92e-02 80 chr10:74442613-74442693 6.89e-01 80 chr18:12302547-12302627 3.78e-01 80 chr1:156095891-156095971 2.11e-01 80 chr2:191184625-191184705 7.63e-02 29_[+4(2.25e-05)]_10_[+4(3.61e-05)]_\ 25 -------------------------------------------------------------------------------- ******************************************************************************** ******************************************************************************** Stopped because requested number of motifs (5) found. ******************************************************************************** CPU: c22n05.farnam.hpc.yale.internal ********************************************************************************