******************************************************************************** MEME - Motif discovery tool ******************************************************************************** MEME version 5.3.3 (Release date: Sun Feb 7 15:39:52 2021 -0800) For further information on how to interpret these results please access https://meme-suite.org/meme. To get a copy of the MEME Suite software please access https://meme-suite.org. ******************************************************************************** ******************************************************************************** REFERENCE ******************************************************************************** If you use this program in your research, please cite: Timothy L. Bailey and Charles Elkan, "Fitting a mixture model by expectation maximization to discover motifs in biopolymers", Proceedings of the Second International Conference on Intelligent Systems for Molecular Biology, pp. 28-36, AAAI Press, Menlo Park, California, 1994. ******************************************************************************** ******************************************************************************** TRAINING SET ******************************************************************************** PRIMARY SEQUENCES= ../result/final_prediction/K562/fasta/RankLinear0.6_40/SETDB1.fasta CONTROL SEQUENCES= --none-- ALPHABET= ACGT Sequence name Weight Length Sequence name Weight Length ------------- ------ ------ ------------- ------ ------ chr19:667312-667392 1.0000 80 chr16:85242490-85242570 1.0000 80 chr19:667513-667593 1.0000 80 chr21:47704257-47704337 1.0000 80 chr1:192170609-192170689 1.0000 80 chr3:152402184-152402264 1.0000 80 chr4:123899440-123899520 1.0000 80 chr11:74538084-74538164 1.0000 80 chr9:138658080-138658160 1.0000 80 chr9:138657783-138657863 1.0000 80 chr6:83741669-83741749 1.0000 80 chr11:76046238-76046318 1.0000 80 chr8:143409959-143410039 1.0000 80 chr10:100883677-10088375 1.0000 80 chr15:102030460-10203054 1.0000 80 chr15:30014763-30014843 1.0000 80 chr22:41611690-41611770 1.0000 80 chr4:75209904-75209984 1.0000 80 chr1:246384138-246384218 1.0000 80 chr14:101277399-10127747 1.0000 80 chr7:2099917-2099997 1.0000 80 chr10:5510430-5510510 1.0000 80 chr5:613336-613416 1.0000 80 chr3:183371512-183371592 1.0000 80 chr9:138921076-138921156 1.0000 80 chr16:85242691-85242771 1.0000 80 chrX:65490019-65490099 1.0000 80 chr3:6591176-6591256 1.0000 80 chr7:75701434-75701514 1.0000 80 chr15:80170596-80170676 1.0000 80 chr2:172483563-172483643 1.0000 80 chr21:34739880-34739960 1.0000 80 chr7:107000136-107000216 1.0000 80 chr19:35663598-35663678 1.0000 80 chr1:245370519-245370599 1.0000 80 chr2:24789216-24789296 1.0000 80 chr11:108499699-10849977 1.0000 80 chr12:62631039-62631119 1.0000 80 chr12:56509243-56509323 1.0000 80 chr5:65098858-65098938 1.0000 80 chr14:101274828-10127490 1.0000 80 chr8:130681935-130682015 1.0000 80 chr5:60289423-60289503 1.0000 80 chr17:1372671-1372751 1.0000 80 chr6:161404586-161404666 1.0000 80 chr1:196504987-196505067 1.0000 80 chr8:17998519-17998599 1.0000 80 chr7:99668845-99668925 1.0000 80 chr3:12906930-12907010 1.0000 80 chr7:64450717-64450797 1.0000 80 chr15:34453700-34453780 1.0000 80 chr1:67533520-67533600 1.0000 80 chr6:142534681-142534761 1.0000 80 chr7:71252678-71252758 1.0000 80 chr18:32864093-32864173 1.0000 80 chr7:158598796-158598876 1.0000 80 chr7:33110042-33110122 1.0000 80 chr12:1530452-1530532 1.0000 80 chr12:51234771-51234851 1.0000 80 chr3:38474505-38474585 1.0000 80 chr1:117291100-117291180 1.0000 80 chr1:117286296-117286376 1.0000 80 chr6:14488002-14488082 1.0000 80 chr19:6454102-6454182 1.0000 80 chr14:102207416-10220749 1.0000 80 chr7:6731302-6731382 1.0000 80 chr3:183014155-183014235 1.0000 80 chr9:132276908-132276988 1.0000 80 chr9:115046348-115046428 1.0000 80 chr19:22130729-22130809 1.0000 80 chr6:118899936-118900016 1.0000 80 chr1:1048910-1048990 1.0000 80 chr20:62776953-62777033 1.0000 80 chr8:102768640-102768720 1.0000 80 chr16:53219837-53219917 1.0000 80 chr15:27422071-27422151 1.0000 80 chr11:59936924-59937004 1.0000 80 chr17:75170864-75170944 1.0000 80 chr1:212075467-212075547 1.0000 80 chr15:85164749-85164829 1.0000 80 chr7:154702812-154702892 1.0000 80 chr1:61431112-61431192 1.0000 80 chr10:29134087-29134167 1.0000 80 chr16:10502814-10502894 1.0000 80 chr14:106873605-10687368 1.0000 80 chr19:24006775-24006855 1.0000 80 chr4:127818345-127818425 1.0000 80 chr12:51331590-51331670 1.0000 80 chr11:61766882-61766962 1.0000 80 chr1:896827-896907 1.0000 80 chr1:15133446-15133526 1.0000 80 chr3:13974537-13974617 1.0000 80 chr7:138114465-138114545 1.0000 80 chr12:127661501-12766158 1.0000 80 chr9:140597210-140597290 1.0000 80 chr6:30827653-30827733 1.0000 80 chr13:29110041-29110121 1.0000 80 chr9:138658280-138658360 1.0000 80 chr13:45451185-45451265 1.0000 80 chr19:35467639-35467719 1.0000 80 chr19:58126861-58126941 1.0000 80 chr16:10434446-10434526 1.0000 80 chr8:144751399-144751479 1.0000 80 chr3:195039952-195040032 1.0000 80 chr17:159238-159318 1.0000 80 chr16:30108410-30108490 1.0000 80 chr5:154265622-154265702 1.0000 80 chr21:36823251-36823331 1.0000 80 chr11:17393341-17393421 1.0000 80 chr9:90282227-90282307 1.0000 80 chr14:106765261-10676534 1.0000 80 chr15:90922615-90922695 1.0000 80 chr22:25112708-25112788 1.0000 80 chr19:9784627-9784707 1.0000 80 chr15:34446941-34447021 1.0000 80 chr12:28522592-28522672 1.0000 80 chr5:53650163-53650243 1.0000 80 chr6:107308820-107308900 1.0000 80 chr20:40228601-40228681 1.0000 80 chr17:75163941-75164021 1.0000 80 chr19:16993106-16993186 1.0000 80 chr7:86957763-86957843 1.0000 80 chr20:32324952-32325032 1.0000 80 chr2:240857181-240857261 1.0000 80 chr19:35449082-35449162 1.0000 80 chr3:128578549-128578629 1.0000 80 chr6:118895553-118895633 1.0000 80 chr1:12700394-12700474 1.0000 80 chr19:42170152-42170232 1.0000 80 chr22:22813684-22813764 1.0000 80 chr7:158642344-158642424 1.0000 80 chr10:17512358-17512438 1.0000 80 chr16:3433177-3433257 1.0000 80 chr18:77782828-77782908 1.0000 80 chr16:89934484-89934564 1.0000 80 chr19:11717493-11717573 1.0000 80 chr14:50780981-50781061 1.0000 80 chr19:48786845-48786925 1.0000 80 chr1:151880054-151880134 1.0000 80 chr7:94287189-94287269 1.0000 80 chr1:12275762-12275842 1.0000 80 chr6:18266172-18266252 1.0000 80 chr4:84299724-84299804 1.0000 80 chr20:36871384-36871464 1.0000 80 chr10:65280882-65280962 1.0000 80 chr10:94474103-94474183 1.0000 80 chr15:80660147-80660227 1.0000 80 chr4:1740279-1740359 1.0000 80 chr7:46508507-46508587 1.0000 80 chr6:83640901-83640981 1.0000 80 chr7:64869105-64869185 1.0000 80 chr2:129226937-129227017 1.0000 80 chr11:13113017-13113097 1.0000 80 chr6:68522808-68522888 1.0000 80 chr2:12364008-12364088 1.0000 80 chr10:72525944-72526024 1.0000 80 chr3:176723977-176724057 1.0000 80 chr2:171780495-171780575 1.0000 80 chr7:150687732-150687812 1.0000 80 chr4:25225515-25225595 1.0000 80 chr6:35876742-35876822 1.0000 80 chr6:147286408-147286488 1.0000 80 chr21:39595992-39596072 1.0000 80 chr7:152430515-152430595 1.0000 80 chr16:3340131-3340211 1.0000 80 chr11:74582239-74582319 1.0000 80 chr16:75179537-75179617 1.0000 80 chr13:41722995-41723075 1.0000 80 chr2:174210968-174211048 1.0000 80 chr7:111582830-111582910 1.0000 80 chr14:107119921-10712000 1.0000 80 chr6:13287531-13287611 1.0000 80 chr3:10211047-10211127 1.0000 80 chr4:10463064-10463144 1.0000 80 chr2:183934061-183934141 1.0000 80 chr7:75436047-75436127 1.0000 80 chr19:58077949-58078029 1.0000 80 chr12:132678763-13267884 1.0000 80 chr19:21702438-21702518 1.0000 80 chr7:10798949-10799029 1.0000 80 chr1:31931307-31931387 1.0000 80 chr15:85164961-85165041 1.0000 80 chr10:71896933-71897013 1.0000 80 chr7:2068526-2068606 1.0000 80 chr10:72408368-72408448 1.0000 80 chr2:31919125-31919205 1.0000 80 chr2:174163426-174163506 1.0000 80 chr9:139667921-139668001 1.0000 80 chr2:86188281-86188361 1.0000 80 chr3:119758638-119758718 1.0000 80 chr3:10287080-10287160 1.0000 80 chr5:103521905-103521985 1.0000 80 chr14:45508256-45508336 1.0000 80 chr2:122440435-122440515 1.0000 80 chr16:3458778-3458858 1.0000 80 chr8:130810795-130810875 1.0000 80 chr12:10063563-10063643 1.0000 80 chr1:153517482-153517562 1.0000 80 chr3:31648093-31648173 1.0000 80 chr3:183371218-183371298 1.0000 80 chr17:18022987-18023067 1.0000 80 chr19:23128524-23128604 1.0000 80 chr7:111436906-111436986 1.0000 80 chr17:37203349-37203429 1.0000 80 chr1:155613165-155613245 1.0000 80 chr6:30377146-30377226 1.0000 80 chr3:33007449-33007529 1.0000 80 chr12:111742521-11174260 1.0000 80 chr1:192134266-192134346 1.0000 80 chr12:51310226-51310306 1.0000 80 chr1:1168006-1168086 1.0000 80 chr14:67960202-67960282 1.0000 80 chr19:6292189-6292269 1.0000 80 chr3:13856752-13856832 1.0000 80 chr6:122760302-122760382 1.0000 80 chr3:193432494-193432574 1.0000 80 chr10:17304658-17304738 1.0000 80 chr3:15697960-15698040 1.0000 80 chr4:129298300-129298380 1.0000 80 chr15:55491030-55491110 1.0000 80 chr7:156490133-156490213 1.0000 80 chr3:156216259-156216339 1.0000 80 chr18:68110322-68110402 1.0000 80 chr2:6985637-6985717 1.0000 80 chr1:17004337-17004417 1.0000 80 chr10:72411584-72411664 1.0000 80 chr4:7240202-7240282 1.0000 80 chr12:32197028-32197108 1.0000 80 chr21:30899025-30899105 1.0000 80 chr16:57286509-57286589 1.0000 80 chr19:970836-970916 1.0000 80 chr1:205125209-205125289 1.0000 80 chr4:151879256-151879336 1.0000 80 chr3:128573382-128573462 1.0000 80 chr17:1505062-1505142 1.0000 80 chr6:150618651-150618731 1.0000 80 chr19:29630304-29630384 1.0000 80 chr4:184426339-184426419 1.0000 80 chr2:33491693-33491773 1.0000 80 chr19:21518670-21518750 1.0000 80 chr7:128523755-128523835 1.0000 80 chr1:192399974-192400054 1.0000 80 chr2:119502485-119502565 1.0000 80 chr7:149226350-149226430 1.0000 80 chr7:99669063-99669143 1.0000 80 chr19:11943563-11943643 1.0000 80 chr2:171679745-171679825 1.0000 80 chr1:212551105-212551185 1.0000 80 chr14:107120121-10712020 1.0000 80 chr3:142824205-142824285 1.0000 80 ******************************************************************************** ******************************************************************************** COMMAND LINE SUMMARY ******************************************************************************** This information can also be useful in the event you wish to report a problem with the MEME software. command: meme -oc ../result/final_prediction/K562/inference_raw/MEME/RankLinear0.6_40_SETDB1/ -dna -nmotifs 5 -w 8 -maxsize 250000 -nostatus ../result/final_prediction/K562/fasta/RankLinear0.6_40/SETDB1.fasta model: mod= zoops nmotifs= 5 evt= inf objective function: em= E-value of product of p-values starts= E-value of product of p-values strands: + width: minw= 8 maxw= 8 nsites: minsites= 2 maxsites= 250 wnsites= 0.8 theta: spmap= uni spfuzz= 0.5 em: prior= dirichlet b= 0.01 maxiter= 50 distance= 1e-05 trim: wg= 11 ws= 1 endgaps= yes data: n= 20000 N= 250 sample: seed= 0 hsfrac= 0 searchsize= 20000 norand= no csites= 1000 Letter frequencies in dataset: A 0.23 C 0.266 G 0.271 T 0.234 Background letter frequencies (from file dataset with add-one prior applied): A 0.23 C 0.266 G 0.271 T 0.234 Background model order: 0 ******************************************************************************** ******************************************************************************** MOTIF TTCTGCAG MEME-1 width = 8 sites = 133 llr = 956 E-value = 2.6e-071 ******************************************************************************** -------------------------------------------------------------------------------- Motif TTCTGCAG MEME-1 Description -------------------------------------------------------------------------------- Simplified A 1::1::8: pos.-specific C 329:19:: probability G :2::9::a matrix T 65:9:12: bits 2.1 1.9 1.7 * * * 1.5 **** * Relative 1.3 ****** Entropy 1.1 ****** (10.4 bits) 0.8 ****** 0.6 * ****** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel TTCTGCAG consensus CC T sequence G -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTCTGCAG MEME-1 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr19:21518670-21518750 44 1.53e-05 caattttact ttctgcag aaagggtgct chr12:32197028-32197108 27 1.53e-05 gcaaattttc ttctgcag aagggtgcag chr18:68110322-68110402 44 1.53e-05 gcacatttat ttctgcag aagggtgctg chr10:17304658-17304738 42 1.53e-05 ggagcaccct ttctgcag aaagtaaatt chr14:67960202-67960282 25 1.53e-05 ggccgcaccc ttctgcag gagtaaattg chr6:30377146-30377226 14 1.53e-05 ggcaattgac ttctgcag aaaggatgct chr12:10063563-10063643 24 1.53e-05 ggcaatttac ttctgcag aagggtgctg chr3:119758638-119758718 26 1.53e-05 agatacaccc ttctgcag aagtaaattg chr2:86188281-86188361 72 1.53e-05 ggtagctcct ttctgcag c chr1:31931307-31931387 16 1.53e-05 gtagcaccct ttctgcag aaagtaaaat chr7:10798949-10799029 12 1.53e-05 gcaaatttac ttctgcag aagggcaccg chr7:152430515-152430595 26 1.53e-05 caattttact ttctgcag aaagggtgct chr4:1740279-1740359 65 1.53e-05 agtttttact ttctgcag aaagggtg chr22:22813684-22813764 26 1.53e-05 agtggcaccc ttctgcag aagtaaattt chr1:12700394-12700474 45 1.53e-05 gcaaatttac ttctgcag aagggtgctg chr6:118895553-118895633 41 1.53e-05 ggcaccaccc ttctgcag aagtaaattg chr17:75163941-75164021 43 1.53e-05 ggcaatttac ttctgcag aaaggtgctg chr20:40228601-40228681 64 1.53e-05 ggcagcacca ttctgcag aagtaaatg chr6:107308820-107308900 19 1.53e-05 ggtagctcct ttctgcag ctggtcaacc chr15:34446941-34447021 46 1.53e-05 ggcaatttac ttctgcag aagggtgcca chr22:25112708-25112788 40 1.53e-05 tgagcactgt ttctgcag aaaataaaaa chr16:30108410-30108490 33 1.53e-05 agcagcaccc ttctgcag aagtaaagat chr8:144751399-144751479 23 1.53e-05 gcaaatttac ttctgcag aagagtgccg chr7:138114465-138114545 29 1.53e-05 gcaaatttac ttctgcag aagggtgctg chr11:61766882-61766962 51 1.53e-05 gcagcacctt ttctgcag taagtaaaat chr16:10502814-10502894 45 1.53e-05 ggcaatttac ttctgcag aagggtgctg chr15:34453700-34453780 21 1.53e-05 ggcaatttac ttctgcag aagggtgcca chr3:12906930-12907010 26 1.53e-05 agtgacaccc ttctgcag aagtaaattg chr8:17998519-17998599 64 1.53e-05 agtggcacct ttctgcag aaaaaaact chr11:108499699-10849977 48 1.53e-05 ggtagcttct ttctgcag gcaggttgtc chr1:245370519-245370599 28 1.53e-05 gcaaatttac ttctgcag aagggtgctt chr21:34739880-34739960 53 1.53e-05 ggcagcactc ttctgcag aagtaaatgt chr1:192134266-192134346 72 5.01e-05 tgccctggtc tcctgcag c chr14:45508256-45508336 45 5.01e-05 gttttggtgt ctctgcag ccctcagcgg chr6:18266172-18266252 38 5.01e-05 ggtagctcct tcctgcag ctggtaggcc chr1:896827-896907 72 5.01e-05 GGTGCTGGCC TCCTGCAG C chr14:102207416-10220749 24 5.01e-05 ggctccagcc ctctgcag acttctgcct chr1:205125209-205125289 50 6.79e-05 ggcagaagtt tgctgcag gggtggagcc chr6:122760302-122760382 34 6.79e-05 ggcagaagcc tgctgcag agatggagcc chr3:33007449-33007529 54 6.79e-05 ggcagaagtt tgctgcag tggtgaggcc chr6:35876742-35876822 18 6.79e-05 ggcagaagtc tgctgcag gggtggagcc chr10:72525944-72526024 22 6.79e-05 ggcagaagtc tgctgcag gggcagagcc chr5:53650163-53650243 39 6.79e-05 gacagaagtt tgctgcag cagtggagcc chr16:53219837-53219917 22 6.79e-05 ggcagaagtg tgctgcag gagtggagcc chr7:33110042-33110122 36 6.79e-05 ggcataagcc tgctgcag gggcggagcc chr6:161404586-161404666 22 6.79e-05 ggcagaagtc tgctgcag ggttggagcc chr11:76046238-76046318 19 6.79e-05 ggcagaagtc tgctgcag gggtggagcc chr6:83741669-83741749 55 6.79e-05 ggcagaggtg tgctgcag ggccgcagcc chr1:12275762-12275842 71 8.34e-05 tcagctcccc ttctgctg ag chr21:47704257-47704337 14 8.34e-05 GATCCGAATC TTCTGCTG GCTCGTGGCC chr12:51331590-51331670 11 9.85e-05 ggtagctgct atctgcag gcaggttgtc chr1:117291100-117291180 31 9.85e-05 ggcagcaccc atctgcag aagtaaatgt chr5:60289423-60289503 63 9.85e-05 tcatcccaac atctgcag ctgtcaacag chr10:100883677-10088375 9 9.85e-05 tagctcct atctgcag acaagtcatc chr7:128523755-128523835 57 1.18e-04 ACAACTGTCG CCCTGCAG CGCCACCTGC chr4:151879256-151879336 71 1.18e-04 agggctccac ccctgcag ca chr4:129298300-129298380 42 1.18e-04 gggctccacc ccctgcag cagacttctg chr8:130810795-130810875 36 1.18e-04 agggctccac ccctgcag cagacttctg chr7:94287189-94287269 43 1.18e-04 AGCGCGCCTC CCCTGCAG CGCGCCTTCC chr15:90922615-90922695 69 1.18e-04 aaggctccac ccctgcag cagt chr9:140597210-140597290 39 1.18e-04 ggggcttcgc ccctgcag gaagcttctg chr6:30827653-30827733 47 1.38e-04 agagctccac cgctgcag caaacttctg chr11:74538084-74538164 55 1.38e-04 caggctccac cgctgcag cagacttctg chr2:24789216-24789296 58 1.53e-04 gtgctcagct ttcagcag agaggagacc chr14:107120121-10712020 68 1.89e-04 TGTTCTGAGC TCCTGCTG GTGGT chr7:149226350-149226430 27 1.89e-04 gcatgactac tcctgctg actagctctt chr19:29630304-29630384 29 1.89e-04 taaactcttt ctctgctg caacacctgc chr12:51310226-51310306 31 1.89e-04 acatgactct tcctgctg actagcttct chr19:23128524-23128604 20 1.89e-04 gcataacgtg tcctgctg acaaactcct chr7:158642344-158642424 64 1.89e-04 ggtggctcct ctctgctg tcaggttgt chr19:35467639-35467719 44 1.89e-04 gaaactcttt ctctgctg ccaaccctgc chr13:29110041-29110121 36 1.89e-04 agggcctcct ctctgctg agagctgaac chr7:154702812-154702892 14 1.89e-04 taaactcttt ctctgctg caaaccctgc chr18:32864093-32864173 37 1.89e-04 ggtagctcct ctctgctg gcaggtcttc chr1:1168006-1168086 8 2.24e-04 GGGGACC TGCTGCTG CTGCCCGCGC chr1:155613165-155613245 71 2.24e-04 attcatgctc acctgcag aa chr3:183371218-183371298 36 2.24e-04 cttttattta tgctgctg aagtggagtg chr1:212075467-212075547 70 2.42e-04 tgggacaacc agctgcag aga chr9:132276908-132276988 25 2.42e-04 caggaaggcc agctgcag agaggagcta chr6:14488002-14488082 42 2.42e-04 cgggacgacc agctgcag agaggagcta chr1:246384138-246384218 32 2.42e-04 tgggacaacc agctgcag agaggagcta chr7:99669063-99669143 33 2.57e-04 CATAGGGTTT TTCTCCAG TGTGGATTCT chr6:118899936-118900016 31 2.85e-04 ggcagcaccc ttctgtag aagtaaattg chr16:57286509-57286589 33 3.20e-04 CACCCTCTGT TCCAGCAG GCTCTGCATG chr10:94474103-94474183 66 3.20e-04 catctctgct ctcagcag agagggt chr3:142824205-142824285 69 3.57e-04 atgggtggca ccctgctg agat chr17:159238-159318 32 3.57e-04 CTGCCAGCCC CCCTGCTG GGGGTCCGGG chr4:127818345-127818425 61 3.57e-04 ctccacctct tgcagcag acttctacct chr10:29134087-29134167 46 3.57e-04 cagcaggctt tgcagcag agagagggtt chr9:115046348-115046428 63 3.57e-04 tacatatagt ccctgctg aggcactgca chr5:613336-613416 68 3.57e-04 cagtggggtt tgcagcag agaaa chr19:58077949-58078029 72 3.95e-04 tgactctcca cgctgctg g chr17:75170864-75170944 31 4.09e-04 ggcaatttac ttttgcag aagggtgccg chr3:183371512-183371592 64 4.09e-04 ctttgcctgg ttttgcag ataatgtta chr6:150618651-150618731 53 5.04e-04 tctccgacca atcagcag cacccattcc chr7:156490133-156490213 15 5.04e-04 agcctgaggg tactgcag gagaccacag chr13:41722995-41723075 57 5.04e-04 acctatcggt ctctccag tctcctgatt chr1:151880054-151880134 50 5.04e-04 accccatggc ctctccag tcctccttca chr11:17393341-17393421 1 5.04e-04 . ttgtgcag gtgagcacaa chr3:193432494-193432574 47 5.69e-04 aggcacaggg acctgctg ccctgcacaa chr12:28522592-28522672 24 5.69e-04 agggctcctc ctctgtag caaacttctg chr13:45451185-45451265 7 5.69e-04 GATACC CTCTGTAG Cggggaccat chr1:196504987-196505067 55 5.69e-04 tgcactccaa acctgctg agtcacactg chr10:5510430-5510510 52 5.69e-04 atgcagcccc acctgctg ctctctggct chr3:176723977-176724057 14 6.03e-04 ggcacaagac tgctgtag ggttggagcc chr15:80170596-80170676 35 6.22e-04 tgcactcaga cccagcag actcaacatc chr19:6454102-6454182 62 6.57e-04 CACTCCACTG TTCTCCTG GCTTCCAAAG chr4:10463064-10463144 11 7.19e-04 ACCGCCCGCG GCCTGCAG TGTCGCTGCG chr2:129226937-129227017 5 7.19e-04 tggt ttctgttg tagccacaag chr1:117286296-117286376 47 7.19e-04 ggcagcaccc ttctgcaa agtaaatgtg chr12:62631039-62631119 55 7.19e-04 cgtagatcca ttctgttg agagcttcta chr2:172483563-172483643 51 7.19e-04 gggacaacct gcctgcag aaagaagcta chr19:970836-970916 21 8.34e-04 AGAGCAGCCT TGTTGCAG GCCCCCGCCC chr16:89934484-89934564 55 8.34e-04 GCGACTGTTT CTCAGCTG TTTGTGGGCT chr9:138921076-138921156 63 8.34e-04 tgggtctcct ctcagctg agagctgagc chr21:30899025-30899105 49 9.40e-04 ggctacacca ctgtgcag acttctgcct chr6:13287531-13287611 33 9.40e-04 TGCCAAGGGC ACCAGCAG GGCCCTGACT chr4:25225515-25225595 62 9.40e-04 tgcactcaga accagcag attaacatcc chr3:183014155-183014235 56 9.40e-04 gtgccaggct ccctccag ccctgaagcc chr17:1372671-1372751 71 9.40e-04 GGGTAAATGC CCCTCCAG GC chr12:56509243-56509323 33 9.40e-04 CTGcataggt cactgcag cctcgacttc chr4:184426339-184426419 20 1.03e-03 ATGTTAGGGC AGCAGCAG CAGCAACTGT chr5:103521905-103521985 23 1.03e-03 ggcagacatc tggtgcag catgactcag chr10:71896933-71897013 65 1.03e-03 aagagagggc tggtgcag ggaaactc chr19:11717493-11717573 15 1.03e-03 agggctccgc ccctgtag cacacctctg chr1:1048910-1048990 45 1.03e-03 AAAGCATGTT AGCAGCAG TGaacctcaa chr1:67533520-67533600 10 1.03e-03 caggcagaa gtctgctg cacaggggag chr2:240857181-240857261 47 1.18e-03 tcagtaaaga tcctcctg ctttacccca chr19:16993106-16993186 46 1.18e-03 tcaataaaga tcctcctg tatacacccc chr1:15133446-15133526 13 1.39e-03 gtcaggactc ccttgcag ctagggatct chr15:85164749-85164829 49 1.39e-03 CTTCAGCCAG AGCTCCAG TCTGATTGCA chr20:62776953-62777033 15 1.39e-03 gcagcaaagg tgctgcaa aaccagcaag chr7:86957763-86957843 68 1.50e-03 ggaggagcta gtcagcag gagta -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTCTGCAG MEME-1 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr19:21518670-21518750 1.5e-05 43_[+1]_29 chr12:32197028-32197108 1.5e-05 26_[+1]_46 chr18:68110322-68110402 1.5e-05 43_[+1]_29 chr10:17304658-17304738 1.5e-05 41_[+1]_31 chr14:67960202-67960282 1.5e-05 24_[+1]_48 chr6:30377146-30377226 1.5e-05 13_[+1]_59 chr12:10063563-10063643 1.5e-05 23_[+1]_49 chr3:119758638-119758718 1.5e-05 25_[+1]_47 chr2:86188281-86188361 1.5e-05 71_[+1]_1 chr1:31931307-31931387 1.5e-05 15_[+1]_57 chr7:10798949-10799029 1.5e-05 11_[+1]_61 chr7:152430515-152430595 1.5e-05 25_[+1]_47 chr4:1740279-1740359 1.5e-05 64_[+1]_8 chr22:22813684-22813764 1.5e-05 25_[+1]_47 chr1:12700394-12700474 1.5e-05 44_[+1]_28 chr6:118895553-118895633 1.5e-05 40_[+1]_32 chr17:75163941-75164021 1.5e-05 42_[+1]_30 chr20:40228601-40228681 1.5e-05 63_[+1]_9 chr6:107308820-107308900 1.5e-05 18_[+1]_54 chr15:34446941-34447021 1.5e-05 45_[+1]_27 chr22:25112708-25112788 1.5e-05 39_[+1]_33 chr16:30108410-30108490 1.5e-05 32_[+1]_40 chr8:144751399-144751479 1.5e-05 22_[+1]_50 chr7:138114465-138114545 1.5e-05 28_[+1]_44 chr11:61766882-61766962 1.5e-05 50_[+1]_22 chr16:10502814-10502894 1.5e-05 44_[+1]_28 chr15:34453700-34453780 1.5e-05 20_[+1]_52 chr3:12906930-12907010 1.5e-05 25_[+1]_47 chr8:17998519-17998599 1.5e-05 63_[+1]_9 chr11:108499699-10849977 1.5e-05 47_[+1]_25 chr1:245370519-245370599 1.5e-05 27_[+1]_45 chr21:34739880-34739960 1.5e-05 52_[+1]_20 chr1:192134266-192134346 5e-05 71_[+1]_1 chr14:45508256-45508336 5e-05 44_[+1]_28 chr6:18266172-18266252 5e-05 37_[+1]_35 chr1:896827-896907 5e-05 71_[+1]_1 chr14:102207416-10220749 5e-05 23_[+1]_49 chr1:205125209-205125289 6.8e-05 49_[+1]_23 chr6:122760302-122760382 6.8e-05 33_[+1]_39 chr3:33007449-33007529 6.8e-05 53_[+1]_19 chr6:35876742-35876822 6.8e-05 17_[+1]_55 chr10:72525944-72526024 6.8e-05 21_[+1]_51 chr5:53650163-53650243 6.8e-05 38_[+1]_34 chr16:53219837-53219917 6.8e-05 21_[+1]_51 chr7:33110042-33110122 6.8e-05 35_[+1]_37 chr6:161404586-161404666 6.8e-05 21_[+1]_51 chr11:76046238-76046318 6.8e-05 18_[+1]_54 chr6:83741669-83741749 6.8e-05 54_[+1]_18 chr1:12275762-12275842 8.3e-05 70_[+1]_2 chr21:47704257-47704337 8.3e-05 13_[+1]_59 chr12:51331590-51331670 9.8e-05 10_[+1]_62 chr1:117291100-117291180 9.8e-05 30_[+1]_42 chr5:60289423-60289503 9.8e-05 62_[+1]_10 chr10:100883677-10088375 9.8e-05 8_[+1]_64 chr7:128523755-128523835 0.00012 56_[+1]_16 chr4:151879256-151879336 0.00012 70_[+1]_2 chr4:129298300-129298380 0.00012 41_[+1]_31 chr8:130810795-130810875 0.00012 35_[+1]_37 chr7:94287189-94287269 0.00012 42_[+1]_30 chr15:90922615-90922695 0.00012 68_[+1]_4 chr9:140597210-140597290 0.00012 38_[+1]_34 chr6:30827653-30827733 0.00014 46_[+1]_26 chr11:74538084-74538164 0.00014 54_[+1]_18 chr2:24789216-24789296 0.00015 57_[+1]_15 chr14:107120121-10712020 0.00019 67_[+1]_5 chr7:149226350-149226430 0.00019 26_[+1]_46 chr19:29630304-29630384 0.00019 28_[+1]_44 chr12:51310226-51310306 0.00019 30_[+1]_42 chr19:23128524-23128604 0.00019 19_[+1]_53 chr7:158642344-158642424 0.00019 63_[+1]_9 chr19:35467639-35467719 0.00019 43_[+1]_29 chr13:29110041-29110121 0.00019 35_[+1]_37 chr7:154702812-154702892 0.00019 13_[+1]_59 chr18:32864093-32864173 0.00019 36_[+1]_36 chr1:1168006-1168086 0.00022 7_[+1]_65 chr1:155613165-155613245 0.00022 70_[+1]_2 chr3:183371218-183371298 0.00022 35_[+1]_37 chr1:212075467-212075547 0.00024 69_[+1]_3 chr9:132276908-132276988 0.00024 24_[+1]_48 chr6:14488002-14488082 0.00024 41_[+1]_31 chr1:246384138-246384218 0.00024 31_[+1]_41 chr7:99669063-99669143 0.00026 32_[+1]_40 chr6:118899936-118900016 0.00029 30_[+1]_42 chr16:57286509-57286589 0.00032 32_[+1]_40 chr10:94474103-94474183 0.00032 65_[+1]_7 chr3:142824205-142824285 0.00036 68_[+1]_4 chr17:159238-159318 0.00036 31_[+1]_41 chr4:127818345-127818425 0.00036 60_[+1]_12 chr10:29134087-29134167 0.00036 45_[+1]_27 chr9:115046348-115046428 0.00036 62_[+1]_10 chr5:613336-613416 0.00036 67_[+1]_5 chr19:58077949-58078029 0.0004 71_[+1]_1 chr17:75170864-75170944 0.00041 30_[+1]_42 chr3:183371512-183371592 0.00041 63_[+1]_9 chr6:150618651-150618731 0.0005 52_[+1]_20 chr7:156490133-156490213 0.0005 14_[+1]_58 chr13:41722995-41723075 0.0005 56_[+1]_16 chr1:151880054-151880134 0.0005 49_[+1]_23 chr11:17393341-17393421 0.0005 [+1]_72 chr3:193432494-193432574 0.00057 46_[+1]_26 chr12:28522592-28522672 0.00057 23_[+1]_49 chr13:45451185-45451265 0.00057 6_[+1]_66 chr1:196504987-196505067 0.00057 54_[+1]_18 chr10:5510430-5510510 0.00057 51_[+1]_21 chr3:176723977-176724057 0.0006 13_[+1]_59 chr15:80170596-80170676 0.00062 34_[+1]_38 chr19:6454102-6454182 0.00066 61_[+1]_11 chr4:10463064-10463144 0.00072 10_[+1]_62 chr2:129226937-129227017 0.00072 4_[+1]_68 chr1:117286296-117286376 0.00072 46_[+1]_26 chr12:62631039-62631119 0.00072 54_[+1]_18 chr2:172483563-172483643 0.00072 50_[+1]_22 chr19:970836-970916 0.00083 20_[+1]_52 chr16:89934484-89934564 0.00083 54_[+1]_18 chr9:138921076-138921156 0.00083 62_[+1]_10 chr21:30899025-30899105 0.00094 48_[+1]_24 chr6:13287531-13287611 0.00094 32_[+1]_40 chr4:25225515-25225595 0.00094 61_[+1]_11 chr3:183014155-183014235 0.00094 55_[+1]_17 chr17:1372671-1372751 0.00094 70_[+1]_2 chr12:56509243-56509323 0.00094 32_[+1]_40 chr4:184426339-184426419 0.001 19_[+1]_53 chr5:103521905-103521985 0.001 22_[+1]_50 chr10:71896933-71897013 0.001 64_[+1]_8 chr19:11717493-11717573 0.001 14_[+1]_58 chr1:1048910-1048990 0.001 44_[+1]_28 chr1:67533520-67533600 0.001 9_[+1]_63 chr2:240857181-240857261 0.0012 46_[+1]_26 chr19:16993106-16993186 0.0012 45_[+1]_27 chr1:15133446-15133526 0.0014 12_[+1]_60 chr15:85164749-85164829 0.0014 48_[+1]_24 chr20:62776953-62777033 0.0014 14_[+1]_58 chr7:86957763-86957843 0.0015 67_[+1]_5 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTCTGCAG MEME-1 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF TTCTGCAG width=8 seqs=133 chr19:21518670-21518750 ( 44) TTCTGCAG 1 chr12:32197028-32197108 ( 27) TTCTGCAG 1 chr18:68110322-68110402 ( 44) TTCTGCAG 1 chr10:17304658-17304738 ( 42) TTCTGCAG 1 chr14:67960202-67960282 ( 25) TTCTGCAG 1 chr6:30377146-30377226 ( 14) TTCTGCAG 1 chr12:10063563-10063643 ( 24) TTCTGCAG 1 chr3:119758638-119758718 ( 26) TTCTGCAG 1 chr2:86188281-86188361 ( 72) TTCTGCAG 1 chr1:31931307-31931387 ( 16) TTCTGCAG 1 chr7:10798949-10799029 ( 12) TTCTGCAG 1 chr7:152430515-152430595 ( 26) TTCTGCAG 1 chr4:1740279-1740359 ( 65) TTCTGCAG 1 chr22:22813684-22813764 ( 26) TTCTGCAG 1 chr1:12700394-12700474 ( 45) TTCTGCAG 1 chr6:118895553-118895633 ( 41) TTCTGCAG 1 chr17:75163941-75164021 ( 43) TTCTGCAG 1 chr20:40228601-40228681 ( 64) TTCTGCAG 1 chr6:107308820-107308900 ( 19) TTCTGCAG 1 chr15:34446941-34447021 ( 46) TTCTGCAG 1 chr22:25112708-25112788 ( 40) TTCTGCAG 1 chr16:30108410-30108490 ( 33) TTCTGCAG 1 chr8:144751399-144751479 ( 23) TTCTGCAG 1 chr7:138114465-138114545 ( 29) TTCTGCAG 1 chr11:61766882-61766962 ( 51) TTCTGCAG 1 chr16:10502814-10502894 ( 45) TTCTGCAG 1 chr15:34453700-34453780 ( 21) TTCTGCAG 1 chr3:12906930-12907010 ( 26) TTCTGCAG 1 chr8:17998519-17998599 ( 64) TTCTGCAG 1 chr11:108499699-10849977 ( 48) TTCTGCAG 1 chr1:245370519-245370599 ( 28) TTCTGCAG 1 chr21:34739880-34739960 ( 53) TTCTGCAG 1 chr1:192134266-192134346 ( 72) TCCTGCAG 1 chr14:45508256-45508336 ( 45) CTCTGCAG 1 chr6:18266172-18266252 ( 38) TCCTGCAG 1 chr1:896827-896907 ( 72) TCCTGCAG 1 chr14:102207416-10220749 ( 24) CTCTGCAG 1 chr1:205125209-205125289 ( 50) TGCTGCAG 1 chr6:122760302-122760382 ( 34) TGCTGCAG 1 chr3:33007449-33007529 ( 54) TGCTGCAG 1 chr6:35876742-35876822 ( 18) TGCTGCAG 1 chr10:72525944-72526024 ( 22) TGCTGCAG 1 chr5:53650163-53650243 ( 39) TGCTGCAG 1 chr16:53219837-53219917 ( 22) TGCTGCAG 1 chr7:33110042-33110122 ( 36) TGCTGCAG 1 chr6:161404586-161404666 ( 22) TGCTGCAG 1 chr11:76046238-76046318 ( 19) TGCTGCAG 1 chr6:83741669-83741749 ( 55) TGCTGCAG 1 chr1:12275762-12275842 ( 71) TTCTGCTG 1 chr21:47704257-47704337 ( 14) TTCTGCTG 1 chr12:51331590-51331670 ( 11) ATCTGCAG 1 chr1:117291100-117291180 ( 31) ATCTGCAG 1 chr5:60289423-60289503 ( 63) ATCTGCAG 1 chr10:100883677-10088375 ( 9) ATCTGCAG 1 chr7:128523755-128523835 ( 57) CCCTGCAG 1 chr4:151879256-151879336 ( 71) CCCTGCAG 1 chr4:129298300-129298380 ( 42) CCCTGCAG 1 chr8:130810795-130810875 ( 36) CCCTGCAG 1 chr7:94287189-94287269 ( 43) CCCTGCAG 1 chr15:90922615-90922695 ( 69) CCCTGCAG 1 chr9:140597210-140597290 ( 39) CCCTGCAG 1 chr6:30827653-30827733 ( 47) CGCTGCAG 1 chr11:74538084-74538164 ( 55) CGCTGCAG 1 chr2:24789216-24789296 ( 58) TTCAGCAG 1 chr14:107120121-10712020 ( 68) TCCTGCTG 1 chr7:149226350-149226430 ( 27) TCCTGCTG 1 chr19:29630304-29630384 ( 29) CTCTGCTG 1 chr12:51310226-51310306 ( 31) TCCTGCTG 1 chr19:23128524-23128604 ( 20) TCCTGCTG 1 chr7:158642344-158642424 ( 64) CTCTGCTG 1 chr19:35467639-35467719 ( 44) CTCTGCTG 1 chr13:29110041-29110121 ( 36) CTCTGCTG 1 chr7:154702812-154702892 ( 14) CTCTGCTG 1 chr18:32864093-32864173 ( 37) CTCTGCTG 1 chr1:1168006-1168086 ( 8) TGCTGCTG 1 chr1:155613165-155613245 ( 71) ACCTGCAG 1 chr3:183371218-183371298 ( 36) TGCTGCTG 1 chr1:212075467-212075547 ( 70) AGCTGCAG 1 chr9:132276908-132276988 ( 25) AGCTGCAG 1 chr6:14488002-14488082 ( 42) AGCTGCAG 1 chr1:246384138-246384218 ( 32) AGCTGCAG 1 chr7:99669063-99669143 ( 33) TTCTCCAG 1 chr6:118899936-118900016 ( 31) TTCTGTAG 1 chr16:57286509-57286589 ( 33) TCCAGCAG 1 chr10:94474103-94474183 ( 66) CTCAGCAG 1 chr3:142824205-142824285 ( 69) CCCTGCTG 1 chr17:159238-159318 ( 32) CCCTGCTG 1 chr4:127818345-127818425 ( 61) TGCAGCAG 1 chr10:29134087-29134167 ( 46) TGCAGCAG 1 chr9:115046348-115046428 ( 63) CCCTGCTG 1 chr5:613336-613416 ( 68) TGCAGCAG 1 chr19:58077949-58078029 ( 72) CGCTGCTG 1 chr17:75170864-75170944 ( 31) TTTTGCAG 1 chr3:183371512-183371592 ( 64) TTTTGCAG 1 chr6:150618651-150618731 ( 53) ATCAGCAG 1 chr7:156490133-156490213 ( 15) TACTGCAG 1 chr13:41722995-41723075 ( 57) CTCTCCAG 1 chr1:151880054-151880134 ( 50) CTCTCCAG 1 chr11:17393341-17393421 ( 1) TTGTGCAG 1 chr3:193432494-193432574 ( 47) ACCTGCTG 1 chr12:28522592-28522672 ( 24) CTCTGTAG 1 chr13:45451185-45451265 ( 7) CTCTGTAG 1 chr1:196504987-196505067 ( 55) ACCTGCTG 1 chr10:5510430-5510510 ( 52) ACCTGCTG 1 chr3:176723977-176724057 ( 14) TGCTGTAG 1 chr15:80170596-80170676 ( 35) CCCAGCAG 1 chr19:6454102-6454182 ( 62) TTCTCCTG 1 chr4:10463064-10463144 ( 11) GCCTGCAG 1 chr2:129226937-129227017 ( 5) TTCTGTTG 1 chr1:117286296-117286376 ( 47) TTCTGCAA 1 chr12:62631039-62631119 ( 55) TTCTGTTG 1 chr2:172483563-172483643 ( 51) GCCTGCAG 1 chr19:970836-970916 ( 21) TGTTGCAG 1 chr16:89934484-89934564 ( 55) CTCAGCTG 1 chr9:138921076-138921156 ( 63) CTCAGCTG 1 chr21:30899025-30899105 ( 49) CTGTGCAG 1 chr6:13287531-13287611 ( 33) ACCAGCAG 1 chr4:25225515-25225595 ( 62) ACCAGCAG 1 chr3:183014155-183014235 ( 56) CCCTCCAG 1 chr17:1372671-1372751 ( 71) CCCTCCAG 1 chr12:56509243-56509323 ( 33) CACTGCAG 1 chr4:184426339-184426419 ( 20) AGCAGCAG 1 chr5:103521905-103521985 ( 23) TGGTGCAG 1 chr10:71896933-71897013 ( 65) TGGTGCAG 1 chr19:11717493-11717573 ( 15) CCCTGTAG 1 chr1:1048910-1048990 ( 45) AGCAGCAG 1 chr1:67533520-67533600 ( 10) GTCTGCTG 1 chr2:240857181-240857261 ( 47) TCCTCCTG 1 chr19:16993106-16993186 ( 46) TCCTCCTG 1 chr1:15133446-15133526 ( 13) CCTTGCAG 1 chr15:85164749-85164829 ( 49) AGCTCCAG 1 chr20:62776953-62777033 ( 15) TGCTGCAA 1 chr7:86957763-86957843 ( 68) GTCAGCAG 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTCTGCAG MEME-1 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 8.4455 E= 2.6e-071 -76 -1 -317 129 -393 -10 -22 111 -1370 182 -317 -296 -103 -1370 -1370 193 -1370 -197 178 -1370 -1370 183 -1370 -215 177 -1370 -1370 -10 -393 -1370 186 -1370 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTCTGCAG MEME-1 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 133 E= 2.6e-071 0.135338 0.263158 0.030075 0.571429 0.015038 0.248120 0.233083 0.503759 0.000000 0.939850 0.030075 0.030075 0.112782 0.000000 0.000000 0.887218 0.000000 0.067669 0.932331 0.000000 0.000000 0.947368 0.000000 0.052632 0.781955 0.000000 0.000000 0.218045 0.015038 0.000000 0.984962 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTCTGCAG MEME-1 regular expression -------------------------------------------------------------------------------- [TC][TCG]CTGC[AT]G -------------------------------------------------------------------------------- Time 5.63 secs. ******************************************************************************** ******************************************************************************** MOTIF CMAGGCAR MEME-2 width = 8 sites = 54 llr = 449 E-value = 2.7e-021 ******************************************************************************** -------------------------------------------------------------------------------- Motif CMAGGCAR MEME-2 Description -------------------------------------------------------------------------------- Simplified A 15a:1:a4 pos.-specific C 85:::a:1 probability G 1::a9::5 matrix T :::::::1 bits 2.1 * * 1.9 ** ** 1.7 ** ** 1.5 ***** Relative 1.3 ***** Entropy 1.1 ******* (12.0 bits) 0.8 ******* 0.6 ******* 0.4 ******** 0.2 ******** 0.0 -------- Multilevel CCAGGCAG consensus A A sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CMAGGCAR MEME-2 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr19:21518670-21518750 29 6.83e-05 attgtctcag caaggcaa ttttactttc chr1:205125209-205125289 37 6.83e-05 gcctggatat ccaggcag aagtttgctg chr12:32197028-32197108 13 6.83e-05 gatttctcag caaggcaa attttcttct chr6:122760302-122760382 21 6.83e-05 gcctgagtaa ccaggcag aagcctgctg chr3:33007449-33007529 41 6.83e-05 gctgggatgt ccaggcag aagtttgctg chr6:30377146-30377226 1 6.83e-05 . caaggcaa ttgacttctg chr3:31648093-31648173 38 6.83e-05 gcctggatgt ccaggcag aagtttgctg chr12:10063563-10063643 11 6.83e-05 gatttctcag caaggcaa tttacttctg chr7:152430515-152430595 11 6.83e-05 attttctcag caaggcaa ttttactttc chr6:35876742-35876822 5 6.83e-05 atgc ccaggcag aagtctgctg chr10:72525944-72526024 9 6.83e-05 ctggatgt ccaggcag aagtctgctg chr2:12364008-12364088 34 6.83e-05 gcctggatgt ccaggcag aagtttgcca chr6:83640901-83640981 61 6.83e-05 gcctggaaat ccaggcag aagtttgctg chr4:1740279-1740359 49 6.83e-05 attttctcag caaggcag tttttacttt chr1:12700394-12700474 31 6.83e-05 gatttctcgg caaggcaa atttacttct chr17:75163941-75164021 30 6.83e-05 tatttctcag caaggcaa tttacttctg chr15:34446941-34447021 33 6.83e-05 gctttctcag caaggcaa tttacttctg chr19:9784627-9784707 33 6.83e-05 cttttctcag caaggcaa tttacttcta chr9:90282227-90282307 47 6.83e-05 tggttctcag caaggcaa ttttgcctcc chr8:144751399-144751479 9 6.83e-05 Cttctcag caaggcaa atttacttct chr19:58126861-58126941 41 6.83e-05 gttttctcag caaggcaa tttacttctg chr7:138114465-138114545 15 6.83e-05 gatttctcag caaggcaa atttacttct chr16:10502814-10502894 32 6.83e-05 gttttcccag caaggcaa tttacttctg chr17:75170864-75170944 18 6.83e-05 gatttctcag caaggcaa tttacttttg chr16:53219837-53219917 9 6.83e-05 ttggatgt ccaggcag aagtgtgctg chr12:1530452-1530532 39 6.83e-05 ttaattatct caaggcag ctgatcagag chr15:34453700-34453780 8 6.83e-05 ttctcag caaggcaa tttacttctg chr6:161404586-161404666 9 6.83e-05 ctggatgt ccaggcag aagtctgctg chr1:245370519-245370599 14 6.83e-05 gatttctcag caaggcaa atttacttct chr11:76046238-76046318 6 6.83e-05 gatgt ccaggcag aagtctgctg chr6:83741669-83741749 42 6.83e-05 gcctggatgt ccaggcag aggtgtgctg chr19:667513-667593 70 6.83e-05 CAGACCAAGC CCAGGCAG ACC chr15:55491030-55491110 58 1.38e-04 atggatggca gcaggcaa agagaatgaa chr10:71896933-71897013 4 1.38e-04 gcg gaaggcaa ggaggagcag chr16:89934484-89934564 2 1.38e-04 A GAAGGCAA GGATGGTTTG chr20:40228601-40228681 51 1.38e-04 tcagacaggt gcaggcag caccattctg chr6:118899936-118900016 18 1.38e-04 cgtgactgat gcaggcag cacccttctg chr1:117286296-117286376 34 1.38e-04 ttggagggat gcaggcag cacccttctg chr14:45508256-45508336 24 2.29e-04 gctcctatcc acaggcag gtcgttttgg chr12:132678763-13267884 73 2.29e-04 cagcagatgc aaaggcag chr12:28522592-28522672 51 2.29e-04 gcctcgacat ccaggcat ttacctacat chr1:61431112-61431192 37 2.29e-04 gcctggacat ccaggcat ttccatacat chr1:117291100-117291180 18 2.29e-04 tcagagggac acaggcag cacccatctg chr7:33110042-33110122 23 2.29e-04 gcctggatgt ccaggcat aagcctgctg chr21:34739880-34739960 40 2.29e-04 gcagatggac acaggcag cactcttctg chr3:152402184-152402264 42 2.29e-04 gctcctttcc acaggcag gtcatcccaa chr18:68110322-68110402 30 3.23e-04 aatttctcag caaggcac atttatttct chr3:193432494-193432574 35 3.23e-04 gtttcctggg ccaggcac agggacctgc chr3:176723977-176724057 1 3.23e-04 . ccaggcac aagactgctg chr20:32324952-32325032 35 3.23e-04 gccaatttat caagacag gggaattgcg chr5:53650163-53650243 26 3.23e-04 acctggatgt ccagacag aagtttgctg chr10:29134087-29134167 31 3.23e-04 accaatacac caagacag caggctttgc chr9:138921076-138921156 9 3.23e-04 agactcag ccagacaa caggatggcc chr15:30014763-30014843 63 3.23e-04 gagcccccca ccagacag tccccactgg -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CMAGGCAR MEME-2 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr19:21518670-21518750 6.8e-05 28_[+2]_44 chr1:205125209-205125289 6.8e-05 36_[+2]_36 chr12:32197028-32197108 6.8e-05 12_[+2]_60 chr6:122760302-122760382 6.8e-05 20_[+2]_52 chr3:33007449-33007529 6.8e-05 40_[+2]_32 chr6:30377146-30377226 6.8e-05 [+2]_72 chr3:31648093-31648173 6.8e-05 37_[+2]_35 chr12:10063563-10063643 6.8e-05 10_[+2]_62 chr7:152430515-152430595 6.8e-05 10_[+2]_62 chr6:35876742-35876822 6.8e-05 4_[+2]_68 chr10:72525944-72526024 6.8e-05 8_[+2]_64 chr2:12364008-12364088 6.8e-05 33_[+2]_39 chr6:83640901-83640981 6.8e-05 60_[+2]_12 chr4:1740279-1740359 6.8e-05 48_[+2]_24 chr1:12700394-12700474 6.8e-05 30_[+2]_42 chr17:75163941-75164021 6.8e-05 29_[+2]_43 chr15:34446941-34447021 6.8e-05 32_[+2]_40 chr19:9784627-9784707 6.8e-05 32_[+2]_40 chr9:90282227-90282307 6.8e-05 46_[+2]_26 chr8:144751399-144751479 6.8e-05 8_[+2]_64 chr19:58126861-58126941 6.8e-05 40_[+2]_32 chr7:138114465-138114545 6.8e-05 14_[+2]_58 chr16:10502814-10502894 6.8e-05 31_[+2]_41 chr17:75170864-75170944 6.8e-05 17_[+2]_55 chr16:53219837-53219917 6.8e-05 8_[+2]_64 chr12:1530452-1530532 6.8e-05 38_[+2]_34 chr15:34453700-34453780 6.8e-05 7_[+2]_65 chr6:161404586-161404666 6.8e-05 8_[+2]_64 chr1:245370519-245370599 6.8e-05 13_[+2]_59 chr11:76046238-76046318 6.8e-05 5_[+2]_67 chr6:83741669-83741749 6.8e-05 41_[+2]_31 chr19:667513-667593 6.8e-05 69_[+2]_3 chr15:55491030-55491110 0.00014 57_[+2]_15 chr10:71896933-71897013 0.00014 3_[+2]_69 chr16:89934484-89934564 0.00014 1_[+2]_71 chr20:40228601-40228681 0.00014 50_[+2]_22 chr6:118899936-118900016 0.00014 17_[+2]_55 chr1:117286296-117286376 0.00014 33_[+2]_39 chr14:45508256-45508336 0.00023 23_[+2]_49 chr12:132678763-13267884 0.00023 72_[+2] chr12:28522592-28522672 0.00023 50_[+2]_22 chr1:61431112-61431192 0.00023 36_[+2]_36 chr1:117291100-117291180 0.00023 17_[+2]_55 chr7:33110042-33110122 0.00023 22_[+2]_50 chr21:34739880-34739960 0.00023 39_[+2]_33 chr3:152402184-152402264 0.00023 41_[+2]_31 chr18:68110322-68110402 0.00032 29_[+2]_43 chr3:193432494-193432574 0.00032 34_[+2]_38 chr3:176723977-176724057 0.00032 [+2]_72 chr20:32324952-32325032 0.00032 34_[+2]_38 chr5:53650163-53650243 0.00032 25_[+2]_47 chr10:29134087-29134167 0.00032 30_[+2]_42 chr9:138921076-138921156 0.00032 8_[+2]_64 chr15:30014763-30014843 0.00032 62_[+2]_10 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CMAGGCAR MEME-2 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF CMAGGCAR width=8 seqs=54 chr19:21518670-21518750 ( 29) CAAGGCAA 1 chr1:205125209-205125289 ( 37) CCAGGCAG 1 chr12:32197028-32197108 ( 13) CAAGGCAA 1 chr6:122760302-122760382 ( 21) CCAGGCAG 1 chr3:33007449-33007529 ( 41) CCAGGCAG 1 chr6:30377146-30377226 ( 1) CAAGGCAA 1 chr3:31648093-31648173 ( 38) CCAGGCAG 1 chr12:10063563-10063643 ( 11) CAAGGCAA 1 chr7:152430515-152430595 ( 11) CAAGGCAA 1 chr6:35876742-35876822 ( 5) CCAGGCAG 1 chr10:72525944-72526024 ( 9) CCAGGCAG 1 chr2:12364008-12364088 ( 34) CCAGGCAG 1 chr6:83640901-83640981 ( 61) CCAGGCAG 1 chr4:1740279-1740359 ( 49) CAAGGCAG 1 chr1:12700394-12700474 ( 31) CAAGGCAA 1 chr17:75163941-75164021 ( 30) CAAGGCAA 1 chr15:34446941-34447021 ( 33) CAAGGCAA 1 chr19:9784627-9784707 ( 33) CAAGGCAA 1 chr9:90282227-90282307 ( 47) CAAGGCAA 1 chr8:144751399-144751479 ( 9) CAAGGCAA 1 chr19:58126861-58126941 ( 41) CAAGGCAA 1 chr7:138114465-138114545 ( 15) CAAGGCAA 1 chr16:10502814-10502894 ( 32) CAAGGCAA 1 chr17:75170864-75170944 ( 18) CAAGGCAA 1 chr16:53219837-53219917 ( 9) CCAGGCAG 1 chr12:1530452-1530532 ( 39) CAAGGCAG 1 chr15:34453700-34453780 ( 8) CAAGGCAA 1 chr6:161404586-161404666 ( 9) CCAGGCAG 1 chr1:245370519-245370599 ( 14) CAAGGCAA 1 chr11:76046238-76046318 ( 6) CCAGGCAG 1 chr6:83741669-83741749 ( 42) CCAGGCAG 1 chr19:667513-667593 ( 70) CCAGGCAG 1 chr15:55491030-55491110 ( 58) GCAGGCAA 1 chr10:71896933-71897013 ( 4) GAAGGCAA 1 chr16:89934484-89934564 ( 2) GAAGGCAA 1 chr20:40228601-40228681 ( 51) GCAGGCAG 1 chr6:118899936-118900016 ( 18) GCAGGCAG 1 chr1:117286296-117286376 ( 34) GCAGGCAG 1 chr14:45508256-45508336 ( 24) ACAGGCAG 1 chr12:132678763-13267884 ( 73) AAAGGCAG 1 chr12:28522592-28522672 ( 51) CCAGGCAT 1 chr1:61431112-61431192 ( 37) CCAGGCAT 1 chr1:117291100-117291180 ( 18) ACAGGCAG 1 chr7:33110042-33110122 ( 23) CCAGGCAT 1 chr21:34739880-34739960 ( 40) ACAGGCAG 1 chr3:152402184-152402264 ( 42) ACAGGCAG 1 chr18:68110322-68110402 ( 30) CAAGGCAC 1 chr3:193432494-193432574 ( 35) CCAGGCAC 1 chr3:176723977-176724057 ( 1) CCAGGCAC 1 chr20:32324952-32325032 ( 35) CAAGACAG 1 chr5:53650163-53650243 ( 26) CCAGACAG 1 chr10:29134087-29134167 ( 31) CAAGACAG 1 chr9:138921076-138921156 ( 9) CCAGACAA 1 chr15:30014763-30014843 ( 63) CCAGACAG 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CMAGGCAR MEME-2 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 9.59303 E= 2.7e-021 -131 158 -129 -1240 101 102 -1240 -1240 212 -1240 -1240 -1240 -1240 -1240 188 -1240 -131 -1240 174 -1240 -1240 191 -1240 -1240 212 -1240 -1240 -1240 76 -226 88 -207 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CMAGGCAR MEME-2 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 54 E= 2.7e-021 0.092593 0.796296 0.111111 0.000000 0.462963 0.537037 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.092593 0.000000 0.907407 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.388889 0.055556 0.500000 0.055556 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CMAGGCAR MEME-2 regular expression -------------------------------------------------------------------------------- C[CA]AGGCA[GA] -------------------------------------------------------------------------------- Time 9.20 secs. ******************************************************************************** ******************************************************************************** MOTIF AGCMCTCA MEME-3 width = 8 sites = 37 llr = 338 E-value = 6.9e-017 ******************************************************************************** -------------------------------------------------------------------------------- Motif AGCMCTCA MEME-3 Description -------------------------------------------------------------------------------- Simplified A 7::4:::a pos.-specific C ::a5a:9: probability G :a:::::: matrix T 3::2:a1: bits 2.1 * * 1.9 ** ** * 1.7 ** ** * 1.5 ** **** Relative 1.3 *** **** Entropy 1.1 *** **** (13.2 bits) 0.8 *** **** 0.6 *** **** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel AGCCCTCA consensus T A sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AGCMCTCA MEME-3 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr6:122760302-122760382 48 1.68e-05 gcagagatgg agccctca cagagaacct chr6:35876742-35876822 32 1.68e-05 gcaggggtgg agccctca tggagaacct chr3:176723977-176724057 28 1.68e-05 gtagggttgg agccctca cagagaacct chr10:72525944-72526024 36 1.68e-05 gcaggggcag agccctca tggataacct chr2:12364008-12364088 61 1.68e-05 acaggggtgg agccctca tcgagaacct chr5:53650163-53650243 53 1.68e-05 gcagcagtgg agccctca tgaaaaactt chr3:195039952-195040032 23 1.68e-05 gcaggggagg agccctca tggagaacct chr16:53219837-53219917 36 1.68e-05 gcaggagtgg agccctca tggagaacct chr7:33110042-33110122 50 1.68e-05 gcaggggcgg agccctca tggagaacct chr1:67533520-67533600 26 1.68e-05 tgcacagggg agccctca tagagaacgt chr6:161404586-161404666 36 1.68e-05 gcagggttgg agccctca tggagaacct chr5:60289423-60289503 1 1.68e-05 . agccctca gcagatagga chr8:130681935-130682015 42 1.68e-05 ccagggtcag agccctca tggagaacct chr15:30014763-30014843 3 1.68e-05 gg agccctca tggagcacct chr11:76046238-76046318 33 1.68e-05 gcaggggtgg agccctca tggagaacct chr6:83741669-83741749 69 1.68e-05 gcagggccgc agccctca tgga chr7:150687732-150687812 52 3.13e-05 caaaagaaat agcactca gatataaatg chr1:12700394-12700474 6 3.13e-05 aaacg agcactca aacaaaagat chr19:9784627-9784707 2 3.13e-05 a agcactca aatataacat chr19:58126861-58126941 16 3.13e-05 aagtgaaacc agcactca ggcaaaagtt chr2:86188281-86188361 32 4.61e-05 tcatctctgc agctctca gcagagagga chr7:158642344-158642424 24 4.61e-05 tgatgtctgc agctctca gcggagagga chr11:108499699-10849977 9 4.61e-05 cagtgtcc agctctca gtgggaagga chr19:21702438-21702518 60 7.80e-05 tgggtctgag tgcactca ataaaatcct chr21:39595992-39596072 32 7.80e-05 ttttattgag tgcactca gacccggcgg chr4:25225515-25225595 52 7.80e-05 atttattgag tgcactca gaaccagcag chr1:151880054-151880134 14 7.80e-05 tgggtctgag tgcactca ataaagttct chr19:35449082-35449162 68 7.80e-05 CCACATTCGC TGCACTCA TAAGG chr2:240857181-240857261 32 7.80e-05 tggctctgaa tgcactca gtaaagatcc chr19:16993106-16993186 31 7.80e-05 tgggtctgag tgcactca ataaagatcc chr15:80170596-80170676 25 7.80e-05 cttttctgag tgcactca gacccagcag chr4:7240202-7240282 50 9.30e-05 gcagcttggt tgctctca ggagtgaggg chr22:25112708-25112788 4 9.30e-05 gtg tgctctca ccattgttcc chrX:65490019-65490099 67 1.08e-04 gtatctttac agccctta ggtcag chr18:68110322-68110402 9 1.21e-04 gaaaaacc agcactta gagaatttct chr7:149226350-149226430 38 1.34e-04 cctgctgact agctctta cagatcgatg chr5:154265622-154265702 71 1.34e-04 tgtgactctg agctctta tt -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AGCMCTCA MEME-3 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr6:122760302-122760382 1.7e-05 47_[+3]_25 chr6:35876742-35876822 1.7e-05 31_[+3]_41 chr3:176723977-176724057 1.7e-05 27_[+3]_45 chr10:72525944-72526024 1.7e-05 35_[+3]_37 chr2:12364008-12364088 1.7e-05 60_[+3]_12 chr5:53650163-53650243 1.7e-05 52_[+3]_20 chr3:195039952-195040032 1.7e-05 22_[+3]_50 chr16:53219837-53219917 1.7e-05 35_[+3]_37 chr7:33110042-33110122 1.7e-05 49_[+3]_23 chr1:67533520-67533600 1.7e-05 25_[+3]_47 chr6:161404586-161404666 1.7e-05 35_[+3]_37 chr5:60289423-60289503 1.7e-05 [+3]_72 chr8:130681935-130682015 1.7e-05 41_[+3]_31 chr15:30014763-30014843 1.7e-05 2_[+3]_70 chr11:76046238-76046318 1.7e-05 32_[+3]_40 chr6:83741669-83741749 1.7e-05 68_[+3]_4 chr7:150687732-150687812 3.1e-05 51_[+3]_21 chr1:12700394-12700474 3.1e-05 5_[+3]_67 chr19:9784627-9784707 3.1e-05 1_[+3]_71 chr19:58126861-58126941 3.1e-05 15_[+3]_57 chr2:86188281-86188361 4.6e-05 31_[+3]_41 chr7:158642344-158642424 4.6e-05 23_[+3]_49 chr11:108499699-10849977 4.6e-05 8_[+3]_64 chr19:21702438-21702518 7.8e-05 59_[+3]_13 chr21:39595992-39596072 7.8e-05 31_[+3]_41 chr4:25225515-25225595 7.8e-05 51_[+3]_21 chr1:151880054-151880134 7.8e-05 13_[+3]_59 chr19:35449082-35449162 7.8e-05 67_[+3]_5 chr2:240857181-240857261 7.8e-05 31_[+3]_41 chr19:16993106-16993186 7.8e-05 30_[+3]_42 chr15:80170596-80170676 7.8e-05 24_[+3]_48 chr4:7240202-7240282 9.3e-05 49_[+3]_23 chr22:25112708-25112788 9.3e-05 3_[+3]_69 chrX:65490019-65490099 0.00011 66_[+3]_6 chr18:68110322-68110402 0.00012 8_[+3]_64 chr7:149226350-149226430 0.00013 37_[+3]_35 chr5:154265622-154265702 0.00013 70_[+3]_2 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AGCMCTCA MEME-3 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF AGCMCTCA width=8 seqs=37 chr6:122760302-122760382 ( 48) AGCCCTCA 1 chr6:35876742-35876822 ( 32) AGCCCTCA 1 chr3:176723977-176724057 ( 28) AGCCCTCA 1 chr10:72525944-72526024 ( 36) AGCCCTCA 1 chr2:12364008-12364088 ( 61) AGCCCTCA 1 chr5:53650163-53650243 ( 53) AGCCCTCA 1 chr3:195039952-195040032 ( 23) AGCCCTCA 1 chr16:53219837-53219917 ( 36) AGCCCTCA 1 chr7:33110042-33110122 ( 50) AGCCCTCA 1 chr1:67533520-67533600 ( 26) AGCCCTCA 1 chr6:161404586-161404666 ( 36) AGCCCTCA 1 chr5:60289423-60289503 ( 1) AGCCCTCA 1 chr8:130681935-130682015 ( 42) AGCCCTCA 1 chr15:30014763-30014843 ( 3) AGCCCTCA 1 chr11:76046238-76046318 ( 33) AGCCCTCA 1 chr6:83741669-83741749 ( 69) AGCCCTCA 1 chr7:150687732-150687812 ( 52) AGCACTCA 1 chr1:12700394-12700474 ( 6) AGCACTCA 1 chr19:9784627-9784707 ( 2) AGCACTCA 1 chr19:58126861-58126941 ( 16) AGCACTCA 1 chr2:86188281-86188361 ( 32) AGCTCTCA 1 chr7:158642344-158642424 ( 24) AGCTCTCA 1 chr11:108499699-10849977 ( 9) AGCTCTCA 1 chr19:21702438-21702518 ( 60) TGCACTCA 1 chr21:39595992-39596072 ( 32) TGCACTCA 1 chr4:25225515-25225595 ( 52) TGCACTCA 1 chr1:151880054-151880134 ( 14) TGCACTCA 1 chr19:35449082-35449162 ( 68) TGCACTCA 1 chr2:240857181-240857261 ( 32) TGCACTCA 1 chr19:16993106-16993186 ( 31) TGCACTCA 1 chr15:80170596-80170676 ( 25) TGCACTCA 1 chr4:7240202-7240282 ( 50) TGCTCTCA 1 chr22:25112708-25112788 ( 4) TGCTCTCA 1 chrX:65490019-65490099 ( 67) AGCCCTTA 1 chr18:68110322-68110402 ( 9) AGCACTTA 1 chr7:149226350-149226430 ( 38) AGCTCTTA 1 chr5:154265622-154265702 ( 71) AGCTCTTA 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AGCMCTCA MEME-3 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 9.81773 E= 6.9e-017 167 -1185 -1185 21 -1185 -1185 188 -1185 -1185 191 -1185 -1185 61 79 -1185 -30 -1185 191 -1185 -1185 -1185 -1185 -1185 210 -1185 175 -1185 -111 212 -1185 -1185 -1185 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AGCMCTCA MEME-3 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 37 E= 6.9e-017 0.729730 0.000000 0.000000 0.270270 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.351351 0.459459 0.000000 0.189189 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.891892 0.000000 0.108108 1.000000 0.000000 0.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AGCMCTCA MEME-3 regular expression -------------------------------------------------------------------------------- [AT]GC[CA]CTCA -------------------------------------------------------------------------------- Time 12.68 secs. ******************************************************************************** ******************************************************************************** MOTIF TGCCTKGM MEME-4 width = 8 sites = 49 llr = 418 E-value = 3.3e-020 ******************************************************************************** -------------------------------------------------------------------------------- Motif TGCCTKGM MEME-4 Description -------------------------------------------------------------------------------- Simplified A :::::::6 pos.-specific C ::99::24 probability G :a:::58: matrix T a:11a4:: bits 2.1 * * 1.9 ** * 1.7 ** * 1.5 ***** Relative 1.3 ***** * Entropy 1.1 ***** ** (12.3 bits) 0.8 ******** 0.6 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel TGCCTGGA consensus T C sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGCCTKGM MEME-4 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr1:205125209-205125289 26 3.30e-05 tgtatggaaa tgcctgga tatccaggca chr21:30899025-30899105 62 3.30e-05 tgcagacttc tgcctgga catccaagca chr3:31648093-31648173 27 3.30e-05 cgtatggaaa tgcctgga tgtccaggca chr8:130810795-130810875 52 3.30e-05 agcagacttc tgcctgga cattcaggca chr2:12364008-12364088 23 3.30e-05 tatatggaaa tgcctgga tgtccaggca chr6:83640901-83640981 50 3.30e-05 tatatggaag tgcctgga aatccaggca chr19:11717493-11717573 31 3.30e-05 agcacacctc tgcctgga cacccaggcg chr15:34446941-34447021 68 3.30e-05 gtgccaatcg tgcctgga gtggt chr6:30827653-30827733 63 3.30e-05 agcaaacttc tgcctgga catccaggtg chr1:61431112-61431192 26 3.30e-05 acaaaacttc tgcctgga catccaggca chr14:102207416-10220749 37 3.30e-05 tgcagacttc tgcctgga catccagaca chr3:38474505-38474585 44 3.30e-05 agcaaacttc tgcctgga catccatgca chr8:130681935-130682015 4 3.30e-05 aat tgcctgga tgtccaagca chr4:75209904-75209984 43 3.30e-05 agcagtcttc tgcctgga tgcccaggcc chr11:74538084-74538164 71 3.30e-05 agcagacttc tgcctgga ca chr1:192170609-192170689 38 3.30e-05 agcaaacttc tgcctgga catccaagcg chr10:17304658-17304738 60 7.13e-05 aaagtaaatt tgccttgc tgagaaaact chr14:67960202-67960282 41 7.13e-05 aggagtaaat tgccttgc tgagaaaact chr3:119758638-119758718 42 7.13e-05 agaagtaaat tgccttgc tgagaaaact chr1:31931307-31931387 34 7.13e-05 aaagtaaaat tgccttgc tgagaaaact chr2:174210968-174211048 25 7.13e-05 aaagtaaatt tgccttgc tgagaaatcc chr22:22813684-22813764 43 7.13e-05 gaagtaaatt tgccttgc cgagaaatcc chr6:118895553-118895633 57 7.13e-05 agaagtaaat tgccttgc tgagaaaacg chr22:25112708-25112788 59 7.13e-05 aaataaaaac tgccttgc cgagaaaatt chr5:154265622-154265702 20 7.13e-05 gacgtaaatt tgccttgc tgagaagtct chr16:30108410-30108490 50 7.13e-05 gaagtaaaga tgccttgc tgggaagtct chr11:61766882-61766962 69 7.13e-05 taagtaaaat tgccttgc tgtg chr6:118899936-118900016 47 7.13e-05 agaagtaaat tgccttgc tgagaaaact chr1:117286296-117286376 63 7.13e-05 aaagtaaatg tgccttgc tgagaaattt chr1:117291100-117291180 48 7.13e-05 gaagtaaatg tgccttgc tgagaaattt chr3:12906930-12907010 42 7.13e-05 agaagtaaat tgccttgc tgagagaatt chr21:34739880-34739960 70 7.13e-05 gaagtaaatg tgccttgc tga chr7:111436906-111436986 49 1.04e-04 tgcagcacca tgccttca accatgggca chr12:10063563-10063643 40 1.04e-04 agaagggtgc tgcctgca tcagccatgc chr11:74582239-74582319 44 1.04e-04 ctgagggaca tgcctgca tccaagagta chr1:12700394-12700474 61 1.04e-04 agaagggtgc tgcctgca tcagtcatga chr7:138114465-138114545 45 1.04e-04 agaagggtgc tgcctgca tcagtcacaa chr1:196504987-196505067 41 1.04e-04 cagagttgtg tgcctgca ctccaaacct chr7:128523755-128523835 21 1.41e-04 GGCTACCCCC TGCCTGCC TGGGCCTCAC chr19:29630304-29630384 1 1.41e-04 . tgccttcc ctgtgattat chr3:13856752-13856832 72 1.41e-04 CTCAGGACTG TGCCTGCC C chr3:33007449-33007529 2 1.56e-04 c tgcctaga tttcagaaga chr6:142534681-142534761 64 1.56e-04 agcacacttc tgcctaga catctgggc chr4:129298300-129298380 58 2.14e-04 agcagacttc tgcttgga cattcaggca chr7:75436047-75436127 39 2.14e-04 gcaattcccc tgtcttga taaattggct chr11:17393341-17393421 51 2.14e-04 gtgaaggtca tgctttga tccatgggca chr9:140597210-140597290 55 2.14e-04 aggaagcttc tgtctgga catctggaca chr14:106873605-10687368 29 2.14e-04 TGCGCCCTCC TGTCTTGA GAGACCTGGT chr10:17512358-17512438 70 2.99e-04 aacccctttt tgcttggc tct -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGCCTKGM MEME-4 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr1:205125209-205125289 3.3e-05 25_[+4]_47 chr21:30899025-30899105 3.3e-05 61_[+4]_11 chr3:31648093-31648173 3.3e-05 26_[+4]_46 chr8:130810795-130810875 3.3e-05 51_[+4]_21 chr2:12364008-12364088 3.3e-05 22_[+4]_50 chr6:83640901-83640981 3.3e-05 49_[+4]_23 chr19:11717493-11717573 3.3e-05 30_[+4]_42 chr15:34446941-34447021 3.3e-05 67_[+4]_5 chr6:30827653-30827733 3.3e-05 62_[+4]_10 chr1:61431112-61431192 3.3e-05 25_[+4]_47 chr14:102207416-10220749 3.3e-05 36_[+4]_36 chr3:38474505-38474585 3.3e-05 43_[+4]_29 chr8:130681935-130682015 3.3e-05 3_[+4]_69 chr4:75209904-75209984 3.3e-05 42_[+4]_30 chr11:74538084-74538164 3.3e-05 70_[+4]_2 chr1:192170609-192170689 3.3e-05 37_[+4]_35 chr10:17304658-17304738 7.1e-05 59_[+4]_13 chr14:67960202-67960282 7.1e-05 40_[+4]_32 chr3:119758638-119758718 7.1e-05 41_[+4]_31 chr1:31931307-31931387 7.1e-05 33_[+4]_39 chr2:174210968-174211048 7.1e-05 24_[+4]_48 chr22:22813684-22813764 7.1e-05 42_[+4]_30 chr6:118895553-118895633 7.1e-05 56_[+4]_16 chr22:25112708-25112788 7.1e-05 58_[+4]_14 chr5:154265622-154265702 7.1e-05 19_[+4]_53 chr16:30108410-30108490 7.1e-05 49_[+4]_23 chr11:61766882-61766962 7.1e-05 68_[+4]_4 chr6:118899936-118900016 7.1e-05 46_[+4]_26 chr1:117286296-117286376 7.1e-05 62_[+4]_10 chr1:117291100-117291180 7.1e-05 47_[+4]_25 chr3:12906930-12907010 7.1e-05 41_[+4]_31 chr21:34739880-34739960 7.1e-05 69_[+4]_3 chr7:111436906-111436986 0.0001 48_[+4]_24 chr12:10063563-10063643 0.0001 39_[+4]_33 chr11:74582239-74582319 0.0001 43_[+4]_29 chr1:12700394-12700474 0.0001 60_[+4]_12 chr7:138114465-138114545 0.0001 44_[+4]_28 chr1:196504987-196505067 0.0001 40_[+4]_32 chr7:128523755-128523835 0.00014 20_[+4]_52 chr19:29630304-29630384 0.00014 [+4]_72 chr3:13856752-13856832 0.00014 71_[+4]_1 chr3:33007449-33007529 0.00016 1_[+4]_71 chr6:142534681-142534761 0.00016 63_[+4]_9 chr4:129298300-129298380 0.00021 57_[+4]_15 chr7:75436047-75436127 0.00021 38_[+4]_34 chr11:17393341-17393421 0.00021 50_[+4]_22 chr9:140597210-140597290 0.00021 54_[+4]_18 chr14:106873605-10687368 0.00021 28_[+4]_44 chr10:17512358-17512438 0.0003 69_[+4]_3 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGCCTKGM MEME-4 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF TGCCTKGM width=8 seqs=49 chr1:205125209-205125289 ( 26) TGCCTGGA 1 chr21:30899025-30899105 ( 62) TGCCTGGA 1 chr3:31648093-31648173 ( 27) TGCCTGGA 1 chr8:130810795-130810875 ( 52) TGCCTGGA 1 chr2:12364008-12364088 ( 23) TGCCTGGA 1 chr6:83640901-83640981 ( 50) TGCCTGGA 1 chr19:11717493-11717573 ( 31) TGCCTGGA 1 chr15:34446941-34447021 ( 68) TGCCTGGA 1 chr6:30827653-30827733 ( 63) TGCCTGGA 1 chr1:61431112-61431192 ( 26) TGCCTGGA 1 chr14:102207416-10220749 ( 37) TGCCTGGA 1 chr3:38474505-38474585 ( 44) TGCCTGGA 1 chr8:130681935-130682015 ( 4) TGCCTGGA 1 chr4:75209904-75209984 ( 43) TGCCTGGA 1 chr11:74538084-74538164 ( 71) TGCCTGGA 1 chr1:192170609-192170689 ( 38) TGCCTGGA 1 chr10:17304658-17304738 ( 60) TGCCTTGC 1 chr14:67960202-67960282 ( 41) TGCCTTGC 1 chr3:119758638-119758718 ( 42) TGCCTTGC 1 chr1:31931307-31931387 ( 34) TGCCTTGC 1 chr2:174210968-174211048 ( 25) TGCCTTGC 1 chr22:22813684-22813764 ( 43) TGCCTTGC 1 chr6:118895553-118895633 ( 57) TGCCTTGC 1 chr22:25112708-25112788 ( 59) TGCCTTGC 1 chr5:154265622-154265702 ( 20) TGCCTTGC 1 chr16:30108410-30108490 ( 50) TGCCTTGC 1 chr11:61766882-61766962 ( 69) TGCCTTGC 1 chr6:118899936-118900016 ( 47) TGCCTTGC 1 chr1:117286296-117286376 ( 63) TGCCTTGC 1 chr1:117291100-117291180 ( 48) TGCCTTGC 1 chr3:12906930-12907010 ( 42) TGCCTTGC 1 chr21:34739880-34739960 ( 70) TGCCTTGC 1 chr7:111436906-111436986 ( 49) TGCCTTCA 1 chr12:10063563-10063643 ( 40) TGCCTGCA 1 chr11:74582239-74582319 ( 44) TGCCTGCA 1 chr1:12700394-12700474 ( 61) TGCCTGCA 1 chr7:138114465-138114545 ( 45) TGCCTGCA 1 chr1:196504987-196505067 ( 41) TGCCTGCA 1 chr7:128523755-128523835 ( 21) TGCCTGCC 1 chr19:29630304-29630384 ( 1) TGCCTTCC 1 chr3:13856752-13856832 ( 72) TGCCTGCC 1 chr3:33007449-33007529 ( 2) TGCCTAGA 1 chr6:142534681-142534761 ( 64) TGCCTAGA 1 chr4:129298300-129298380 ( 58) TGCTTGGA 1 chr7:75436047-75436127 ( 39) TGTCTTGA 1 chr11:17393341-17393421 ( 51) TGCTTTGA 1 chr9:140597210-140597290 ( 55) TGTCTGGA 1 chr14:106873605-10687368 ( 29) TGTCTTGA 1 chr10:17512358-17512438 ( 70) TGCTTGGC 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGCCTKGM MEME-4 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 9.65557 E= 3.3e-020 -1226 -1226 -1226 210 -1226 -1226 188 -1226 -1226 182 -1226 -193 -1226 182 -1226 -193 -1226 -1226 -1226 210 -249 -1226 97 88 -1226 -53 159 -1226 137 62 -1226 -1226 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGCCTKGM MEME-4 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 49 E= 3.3e-020 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.938776 0.000000 0.061224 0.000000 0.938776 0.000000 0.061224 0.000000 0.000000 0.000000 1.000000 0.040816 0.000000 0.530612 0.428571 0.000000 0.183673 0.816327 0.000000 0.591837 0.408163 0.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGCCTKGM MEME-4 regular expression -------------------------------------------------------------------------------- TGCCT[GT]G[AC] -------------------------------------------------------------------------------- Time 16.10 secs. ******************************************************************************** ******************************************************************************** MOTIF KTTCTCAG MEME-5 width = 8 sites = 56 llr = 431 E-value = 3.2e-008 ******************************************************************************** -------------------------------------------------------------------------------- Motif KTTCTCAG MEME-5 Description -------------------------------------------------------------------------------- Simplified A ::::::9: pos.-specific C 2::a18:: probability G 332::2:a matrix T 578:9:1: bits 2.1 1.9 * 1.7 * * 1.5 *** ** Relative 1.3 ******* Entropy 1.1 ******* (11.1 bits) 0.8 ******* 0.6 ******* 0.4 ******** 0.2 ******** 0.0 -------- Multilevel TTTCTCAG consensus GG sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif KTTCTCAG MEME-5 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr12:32197028-32197108 5 1.32e-05 aaga tttctcag caaggcaaat chr18:68110322-68110402 22 1.32e-05 acttagagaa tttctcag caaggcacat chr12:10063563-10063643 3 1.32e-05 ga tttctcag caaggcaatt chr7:152430515-152430595 3 1.32e-05 at tttctcag caaggcaatt chr4:1740279-1740359 41 1.32e-05 gaacattaat tttctcag caaggcagtt chr17:75163941-75164021 22 1.32e-05 agacaaatta tttctcag caaggcaatt chr15:34446941-34447021 25 1.32e-05 ggcaaaaagc tttctcag caaggcaatt chr19:9784627-9784707 25 1.32e-05 aacattttct tttctcag caaggcaatt chr19:58126861-58126941 33 1.32e-05 aggcaaaagt tttctcag caaggcaatt chr7:138114465-138114545 7 1.32e-05 taagga tttctcag caaggcaaat chr17:75170864-75170944 10 1.32e-05 gacaaagga tttctcag caaggcaatt chr1:245370519-245370599 6 1.32e-05 agaga tttctcag caaggcaaat chr9:90282227-90282307 39 2.85e-05 TAAGGcagtg gttctcag caaggcaatt chr10:100883677-10088375 41 2.85e-05 TGAGTGTGCA GTTCTCAG CAGAGaggag chr19:21518670-21518750 21 5.89e-05 gacaaaaaat tgtctcag caaggcaatt chr19:29630304-29630384 47 5.89e-05 caacacctgc tgtctcag tgtattggct chr2:174210968-174211048 45 5.89e-05 agaaatcctt tgtctcag tgctggttct chr16:30108410-30108490 70 5.89e-05 ggaagtcttc tgtctcag tgc chr8:144751399-144751479 1 5.89e-05 . Cttctcag caaggcaaat chr19:35467639-35467719 62 5.89e-05 ccaaccctgc tgtctcag tggaatggtc chr14:106765261-10676534 62 7.24e-05 TCCCCGAGTG TTTCTGAG CGCCCCCTGG chr15:80170596-80170676 17 7.24e-05 aggaggatct tttctgag tgcactcaga chr6:83741669-83741749 11 7.24e-05 tccaccaaga tttctgag actgtatgga chr16:10434446-10434526 16 1.19e-04 agccctgtct ttgctcag ggctcagcct chr14:107120121-10712020 21 1.34e-04 CCCGCTGGTG GTTCTGAG CGCCCCCTGG chr14:107119921-10712000 47 1.34e-04 CCCGCTGGTG GTTCTGAG CGCCCCCTGG chr14:106873605-10687368 68 1.34e-04 CCCCCTAGTG GTTCTGAG CCCCC chr7:128523755-128523835 38 1.52e-04 CTGGGCCTCA CGTCTCAG CACAACTGTC chr21:36823251-36823331 49 1.52e-04 aggccattcg cgtctcag gcttggccca chr16:10502814-10502894 24 1.67e-04 gggcaaaagt tttcccag caaggcaatt chr4:151879256-151879336 51 2.00e-04 cttagcagag gttctctg tgagggctcc chr12:28522592-28522672 4 2.00e-04 gag gttctctg tgagggctcc chr15:90922615-90922695 49 2.00e-04 cctagtagag gttctctg tgaaggctcc chr12:51331590-51331670 69 2.00e-04 gggactttat gtgctcag aatg chr2:24789216-24789296 48 2.00e-04 gttccattgt gtgctcag ctttcagcag chr16:85242691-85242771 72 2.00e-04 CAGTGTTTCT GTTCTCTg c chr4:75209904-75209984 7 2.00e-04 gtagag gttctctg tgtgggctcc chr9:139667921-139668001 6 3.15e-04 tacaa ctgctcag aggcagccat chr7:75436047-75436127 19 3.15e-04 aattaaattc cttctctg ttgcaattcc chr16:3340131-3340211 16 3.15e-04 GACTTTACCC CTTCTCTG AGTGTGGGGA chr7:150687732-150687812 69 3.15e-04 agatataaat gttcccag caag chr7:64869105-64869185 73 3.15e-04 acaagtgctg tggctcag chr20:40228601-40228681 20 3.15e-04 ctgctctacc ctgctcag tgtgctcttg chr19:24006775-24006855 59 3.15e-04 aggtgcacac tggctcag tggattcaca chr6:142534681-142534761 4 3.15e-04 tat cttctctg cactgctctt chr19:21702438-21702518 52 3.33e-04 taatccactg ggtctgag tgcactcaat chr13:41722995-41723075 13 3.33e-04 aaatccactg ggtctgag tgcactaaaa chr1:151880054-151880134 6 3.33e-04 cgctg ggtctgag tgcactcaat chr19:16993106-16993186 23 3.33e-04 gagtccagtg ggtctgag tgcactcaat chr12:127661501-12766158 52 3.62e-04 taaaattacc ttgctgag aaaagttttt chr2:171679745-171679825 63 3.96e-04 TGCACCTGAT CTTCCCAG CCTCCCTGGG chr7:94287189-94287269 56 3.96e-04 TGCAGCGCGC CTTCCCAG AGCGCGCCTT chr11:108499699-10849977 62 3.96e-04 gcaggcaggt tgtcccag accagtcaag chr4:123899440-123899520 30 3.96e-04 ataggcaggg tgtcccag tgaatgtcct chr6:14488002-14488082 6 4.35e-04 gccct gggctcag ccggagctga chr3:183371512-183371592 16 5.29e-04 agaacttgtt tttctcat acttgctttt -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif KTTCTCAG MEME-5 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr12:32197028-32197108 1.3e-05 4_[+5]_68 chr18:68110322-68110402 1.3e-05 21_[+5]_51 chr12:10063563-10063643 1.3e-05 2_[+5]_70 chr7:152430515-152430595 1.3e-05 2_[+5]_70 chr4:1740279-1740359 1.3e-05 40_[+5]_32 chr17:75163941-75164021 1.3e-05 21_[+5]_51 chr15:34446941-34447021 1.3e-05 24_[+5]_48 chr19:9784627-9784707 1.3e-05 24_[+5]_48 chr19:58126861-58126941 1.3e-05 32_[+5]_40 chr7:138114465-138114545 1.3e-05 6_[+5]_66 chr17:75170864-75170944 1.3e-05 9_[+5]_63 chr1:245370519-245370599 1.3e-05 5_[+5]_67 chr9:90282227-90282307 2.9e-05 38_[+5]_34 chr10:100883677-10088375 2.9e-05 40_[+5]_32 chr19:21518670-21518750 5.9e-05 20_[+5]_52 chr19:29630304-29630384 5.9e-05 46_[+5]_26 chr2:174210968-174211048 5.9e-05 44_[+5]_28 chr16:30108410-30108490 5.9e-05 69_[+5]_3 chr8:144751399-144751479 5.9e-05 [+5]_72 chr19:35467639-35467719 5.9e-05 61_[+5]_11 chr14:106765261-10676534 7.2e-05 61_[+5]_11 chr15:80170596-80170676 7.2e-05 16_[+5]_56 chr6:83741669-83741749 7.2e-05 10_[+5]_62 chr16:10434446-10434526 0.00012 15_[+5]_57 chr14:107120121-10712020 0.00013 20_[+5]_52 chr14:107119921-10712000 0.00013 46_[+5]_26 chr14:106873605-10687368 0.00013 67_[+5]_5 chr7:128523755-128523835 0.00015 37_[+5]_35 chr21:36823251-36823331 0.00015 48_[+5]_24 chr16:10502814-10502894 0.00017 23_[+5]_49 chr4:151879256-151879336 0.0002 50_[+5]_22 chr12:28522592-28522672 0.0002 3_[+5]_69 chr15:90922615-90922695 0.0002 48_[+5]_24 chr12:51331590-51331670 0.0002 68_[+5]_4 chr2:24789216-24789296 0.0002 47_[+5]_25 chr16:85242691-85242771 0.0002 71_[+5]_1 chr4:75209904-75209984 0.0002 6_[+5]_66 chr9:139667921-139668001 0.00031 5_[+5]_67 chr7:75436047-75436127 0.00031 18_[+5]_54 chr16:3340131-3340211 0.00031 15_[+5]_57 chr7:150687732-150687812 0.00031 68_[+5]_4 chr7:64869105-64869185 0.00031 72_[+5] chr20:40228601-40228681 0.00031 19_[+5]_53 chr19:24006775-24006855 0.00031 58_[+5]_14 chr6:142534681-142534761 0.00031 3_[+5]_69 chr19:21702438-21702518 0.00033 51_[+5]_21 chr13:41722995-41723075 0.00033 12_[+5]_60 chr1:151880054-151880134 0.00033 5_[+5]_67 chr19:16993106-16993186 0.00033 22_[+5]_50 chr12:127661501-12766158 0.00036 51_[+5]_21 chr2:171679745-171679825 0.0004 62_[+5]_10 chr7:94287189-94287269 0.0004 55_[+5]_17 chr11:108499699-10849977 0.0004 61_[+5]_11 chr4:123899440-123899520 0.0004 29_[+5]_43 chr6:14488002-14488082 0.00043 5_[+5]_67 chr3:183371512-183371592 0.00053 15_[+5]_57 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif KTTCTCAG MEME-5 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF KTTCTCAG width=8 seqs=56 chr12:32197028-32197108 ( 5) TTTCTCAG 1 chr18:68110322-68110402 ( 22) TTTCTCAG 1 chr12:10063563-10063643 ( 3) TTTCTCAG 1 chr7:152430515-152430595 ( 3) TTTCTCAG 1 chr4:1740279-1740359 ( 41) TTTCTCAG 1 chr17:75163941-75164021 ( 22) TTTCTCAG 1 chr15:34446941-34447021 ( 25) TTTCTCAG 1 chr19:9784627-9784707 ( 25) TTTCTCAG 1 chr19:58126861-58126941 ( 33) TTTCTCAG 1 chr7:138114465-138114545 ( 7) TTTCTCAG 1 chr17:75170864-75170944 ( 10) TTTCTCAG 1 chr1:245370519-245370599 ( 6) TTTCTCAG 1 chr9:90282227-90282307 ( 39) GTTCTCAG 1 chr10:100883677-10088375 ( 41) GTTCTCAG 1 chr19:21518670-21518750 ( 21) TGTCTCAG 1 chr19:29630304-29630384 ( 47) TGTCTCAG 1 chr2:174210968-174211048 ( 45) TGTCTCAG 1 chr16:30108410-30108490 ( 70) TGTCTCAG 1 chr8:144751399-144751479 ( 1) CTTCTCAG 1 chr19:35467639-35467719 ( 62) TGTCTCAG 1 chr14:106765261-10676534 ( 62) TTTCTGAG 1 chr15:80170596-80170676 ( 17) TTTCTGAG 1 chr6:83741669-83741749 ( 11) TTTCTGAG 1 chr16:10434446-10434526 ( 16) TTGCTCAG 1 chr14:107120121-10712020 ( 21) GTTCTGAG 1 chr14:107119921-10712000 ( 47) GTTCTGAG 1 chr14:106873605-10687368 ( 68) GTTCTGAG 1 chr7:128523755-128523835 ( 38) CGTCTCAG 1 chr21:36823251-36823331 ( 49) CGTCTCAG 1 chr16:10502814-10502894 ( 24) TTTCCCAG 1 chr4:151879256-151879336 ( 51) GTTCTCTG 1 chr12:28522592-28522672 ( 4) GTTCTCTG 1 chr15:90922615-90922695 ( 49) GTTCTCTG 1 chr12:51331590-51331670 ( 69) GTGCTCAG 1 chr2:24789216-24789296 ( 48) GTGCTCAG 1 chr16:85242691-85242771 ( 72) GTTCTCTG 1 chr4:75209904-75209984 ( 7) GTTCTCTG 1 chr9:139667921-139668001 ( 6) CTGCTCAG 1 chr7:75436047-75436127 ( 19) CTTCTCTG 1 chr16:3340131-3340211 ( 16) CTTCTCTG 1 chr7:150687732-150687812 ( 69) GTTCCCAG 1 chr7:64869105-64869185 ( 73) TGGCTCAG 1 chr20:40228601-40228681 ( 20) CTGCTCAG 1 chr19:24006775-24006855 ( 59) TGGCTCAG 1 chr6:142534681-142534761 ( 4) CTTCTCTG 1 chr19:21702438-21702518 ( 52) GGTCTGAG 1 chr13:41722995-41723075 ( 13) GGTCTGAG 1 chr1:151880054-151880134 ( 6) GGTCTGAG 1 chr19:16993106-16993186 ( 23) GGTCTGAG 1 chr12:127661501-12766158 ( 52) TTGCTGAG 1 chr2:171679745-171679825 ( 63) CTTCCCAG 1 chr7:94287189-94287269 ( 56) CTTCCCAG 1 chr11:108499699-10849977 ( 62) TGTCCCAG 1 chr4:123899440-123899520 ( 30) TGTCCCAG 1 chr6:14488002-14488082 ( 6) GGGCTCAG 1 chr3:183371512-183371592 ( 16) TTTCTCAT 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif KTTCTCAG MEME-5 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 9.56875 E= 3.2e-008 -1245 -57 25 110 -1245 -1245 8 161 -1245 -1245 -75 185 -1245 191 -1245 -1245 -1245 -131 -1245 193 -1245 160 -46 -1245 190 -1245 -1245 -71 -1245 -1245 186 -371 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif KTTCTCAG MEME-5 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 56 E= 3.2e-008 0.000000 0.178571 0.321429 0.500000 0.000000 0.000000 0.285714 0.714286 0.000000 0.000000 0.160714 0.839286 0.000000 1.000000 0.000000 0.000000 0.000000 0.107143 0.000000 0.892857 0.000000 0.803571 0.196429 0.000000 0.857143 0.000000 0.000000 0.142857 0.000000 0.000000 0.982143 0.017857 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif KTTCTCAG MEME-5 regular expression -------------------------------------------------------------------------------- [TG][TG]TCTCAG -------------------------------------------------------------------------------- Time 19.46 secs. ******************************************************************************** ******************************************************************************** SUMMARY OF MOTIFS ******************************************************************************** -------------------------------------------------------------------------------- Combined block diagrams: non-overlapping sites with p-value < 0.0001 -------------------------------------------------------------------------------- SEQUENCE NAME COMBINED P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr19:667312-667392 3.46e-01 80 chr16:85242490-85242570 6.80e-01 80 chr19:667513-667593 6.24e-02 7_[+2(6.83e-05)]_39_[+2(6.83e-05)]_\ 7_[+2(6.83e-05)]_3 chr21:47704257-47704337 1.78e-01 13_[+1(8.34e-05)]_59 chr1:192170609-192170689 1.81e-02 37_[+4(3.30e-05)]_35 chr3:152402184-152402264 2.96e-01 80 chr4:123899440-123899520 7.39e-03 80 chr11:74538084-74538164 1.64e-03 70_[+4(3.30e-05)]_2 chr9:138658080-138658160 9.00e-01 80 chr9:138657783-138657863 6.89e-01 80 chr6:83741669-83741749 2.79e-07 10_[+5(7.24e-05)]_23_[+2(6.83e-05)]_\ 5_[+1(6.79e-05)]_6_[+3(1.68e-05)]_4 chr11:76046238-76046318 8.99e-05 5_[+2(6.83e-05)]_5_[+1(6.79e-05)]_6_\ [+3(1.68e-05)]_40 chr8:143409959-143410039 1.97e-01 80 chr10:100883677-10088375 7.22e-05 8_[+1(9.85e-05)]_24_[+5(2.85e-05)]_\ 32 chr15:102030460-10203054 9.23e-02 80 chr15:30014763-30014843 3.03e-03 2_[+3(1.68e-05)]_70 chr22:41611690-41611770 9.90e-01 80 chr4:75209904-75209984 8.97e-04 42_[+4(3.30e-05)]_30 chr1:246384138-246384218 1.95e-01 80 chr14:101277399-10127747 9.70e-01 80 chr7:2099917-2099997 8.05e-01 80 chr10:5510430-5510510 2.93e-02 80 chr5:613336-613416 7.20e-02 80 chr3:183371512-183371592 1.63e-02 80 chr9:138921076-138921156 1.42e-02 80 chr16:85242691-85242771 2.77e-01 80 chrX:65490019-65490099 4.60e-02 80 chr3:6591176-6591256 5.60e-01 80 chr7:75701434-75701514 5.41e-01 80 chr15:80170596-80170676 1.91e-04 16_[+5(7.24e-05)]_[+3(7.80e-05)]_48 chr2:172483563-172483643 2.08e-02 80 chr21:34739880-34739960 8.01e-06 52_[+1(1.53e-05)]_9_[+4(7.13e-05)]_\ 3 chr7:107000136-107000216 6.68e-01 80 chr19:35663598-35663678 2.30e-01 80 chr1:245370519-245370599 9.37e-06 5_[+5(1.32e-05)]_[+2(6.83e-05)]_6_\ [+1(1.53e-05)]_45 chr2:24789216-24789296 3.14e-03 80 chr11:108499699-10849977 4.21e-06 8_[+3(4.61e-05)]_31_[+1(1.53e-05)]_\ 25 chr12:62631039-62631119 3.27e-01 80 chr12:56509243-56509323 4.67e-01 80 chr5:65098858-65098938 8.84e-02 80 chr14:101274828-10127490 9.36e-01 80 chr8:130681935-130682015 9.44e-05 3_[+4(3.30e-05)]_30_[+3(1.68e-05)]_\ 31 chr5:60289423-60289503 1.62e-03 [+3(1.68e-05)]_54_[+1(9.85e-05)]_10 chr17:1372671-1372751 7.77e-01 80 chr6:161404586-161404666 1.02e-04 8_[+2(6.83e-05)]_5_[+1(6.79e-05)]_6_\ [+3(1.68e-05)]_37 chr1:196504987-196505067 1.32e-03 80 chr8:17998519-17998599 5.13e-03 63_[+1(1.53e-05)]_9 chr7:99668845-99668925 3.95e-01 80 chr3:12906930-12907010 4.05e-04 25_[+1(1.53e-05)]_8_[+4(7.13e-05)]_\ 31 chr7:64450717-64450797 4.50e-01 80 chr15:34453700-34453780 6.44e-04 7_[+2(6.83e-05)]_5_[+1(1.53e-05)]_\ 52 chr1:67533520-67533600 2.58e-03 25_[+3(1.68e-05)]_47 chr6:142534681-142534761 3.79e-03 80 chr7:71252678-71252758 3.34e-02 80 chr18:32864093-32864173 2.79e-02 80 chr7:158598796-158598876 9.43e-01 80 chr7:33110042-33110122 4.06e-05 35_[+1(6.79e-05)]_6_[+3(1.68e-05)]_\ 23 chr12:1530452-1530532 3.17e-02 38_[+2(6.83e-05)]_34 chr12:51234771-51234851 6.58e-01 80 chr3:38474505-38474585 3.47e-02 43_[+4(3.30e-05)]_29 chr1:117291100-117291180 8.78e-06 30_[+1(9.85e-05)]_9_[+4(7.13e-05)]_\ 25 chr1:117286296-117286376 8.10e-05 62_[+4(7.13e-05)]_10 chr6:14488002-14488082 1.08e-02 80 chr19:6454102-6454182 6.31e-02 80 chr14:102207416-10220749 9.12e-05 23_[+1(5.01e-05)]_5_[+4(3.30e-05)]_\ 36 chr7:6731302-6731382 5.33e-01 80 chr3:183014155-183014235 2.02e-02 80 chr9:132276908-132276988 1.80e-01 80 chr9:115046348-115046428 2.32e-02 80 chr19:22130729-22130809 4.29e-01 80 chr6:118899936-118900016 7.53e-05 46_[+4(7.13e-05)]_26 chr1:1048910-1048990 1.32e-01 80 chr20:62776953-62777033 5.31e-01 80 chr8:102768640-102768720 3.78e-01 80 chr16:53219837-53219917 1.02e-04 8_[+2(6.83e-05)]_5_[+1(6.79e-05)]_6_\ [+3(1.68e-05)]_37 chr15:27422071-27422151 3.60e-01 80 chr11:59936924-59937004 3.23e-01 80 chr17:75170864-75170944 6.42e-05 9_[+5(1.32e-05)]_[+2(6.83e-05)]_55 chr1:212075467-212075547 2.37e-01 80 chr15:85164749-85164829 2.82e-01 80 chr7:154702812-154702892 1.03e-02 80 chr1:61431112-61431192 3.55e-03 25_[+4(3.30e-05)]_47 chr10:29134087-29134167 5.92e-02 80 chr16:10502814-10502894 1.65e-05 31_[+2(6.83e-05)]_5_[+1(1.53e-05)]_\ 28 chr14:106873605-10687368 8.29e-03 80 chr19:24006775-24006855 2.06e-01 80 chr4:127818345-127818425 3.09e-01 80 chr12:51331590-51331670 4.98e-04 10_[+1(9.85e-05)]_62 chr11:61766882-61766962 2.03e-04 50_[+1(1.53e-05)]_10_[+4(7.13e-05)]_\ 4 chr1:896827-896907 5.33e-02 71_[+1(5.01e-05)]_1 chr1:15133446-15133526 2.04e-01 80 chr3:13974537-13974617 8.03e-01 80 chr7:138114465-138114545 2.73e-07 6_[+5(1.32e-05)]_[+2(6.83e-05)]_6_\ [+1(1.53e-05)]_44 chr12:127661501-12766158 5.23e-02 80 chr9:140597210-140597290 9.56e-03 80 chr6:30827653-30827733 9.10e-03 62_[+4(3.30e-05)]_10 chr13:29110041-29110121 4.08e-02 80 chr9:138658280-138658360 7.23e-01 80 chr13:45451185-45451265 1.69e-01 80 chr19:35467639-35467719 3.00e-03 61_[+5(5.89e-05)]_11 chr19:58126861-58126941 1.18e-05 15_[+3(3.13e-05)]_9_[+5(1.32e-05)]_\ [+2(6.83e-05)]_32 chr16:10434446-10434526 1.23e-01 80 chr8:144751399-144751479 6.33e-05 [+5(5.89e-05)]_[+2(6.83e-05)]_6_\ [+1(1.53e-05)]_50 chr3:195039952-195040032 3.44e-02 22_[+3(1.68e-05)]_50 chr17:159238-159318 5.17e-02 80 chr16:30108410-30108490 1.71e-05 32_[+1(1.53e-05)]_9_[+4(7.13e-05)]_\ 12_[+5(5.89e-05)]_3 chr5:154265622-154265702 6.67e-04 19_[+4(7.13e-05)]_53 chr21:36823251-36823331 6.80e-02 80 chr11:17393341-17393421 3.25e-02 80 chr9:90282227-90282307 1.75e-03 38_[+5(2.85e-05)]_[+2(6.83e-05)]_26 chr14:106765261-10676534 5.03e-02 61_[+5(7.24e-05)]_11 chr15:90922615-90922695 1.65e-02 80 chr22:25112708-25112788 1.21e-05 3_[+3(9.30e-05)]_28_[+1(1.53e-05)]_\ 11_[+4(7.13e-05)]_14 chr19:9784627-9784707 4.38e-06 1_[+3(3.13e-05)]_15_[+5(1.32e-05)]_\ [+2(6.83e-05)]_20_[+3(6.32e-05)]_12 chr15:34446941-34447021 2.17e-08 24_[+5(1.32e-05)]_[+2(6.83e-05)]_5_\ [+1(1.53e-05)]_14_[+4(3.30e-05)]_5 chr12:28522592-28522672 9.31e-04 80 chr5:53650163-53650243 1.51e-04 38_[+1(6.79e-05)]_6_[+3(1.68e-05)]_\ 20 chr6:107308820-107308900 2.68e-03 18_[+1(1.53e-05)]_54 chr20:40228601-40228681 1.77e-04 63_[+1(1.53e-05)]_9 chr17:75163941-75164021 1.29e-05 21_[+5(1.32e-05)]_[+2(6.83e-05)]_5_\ [+1(1.53e-05)]_30 chr19:16993106-16993186 6.02e-03 30_[+3(7.80e-05)]_42 chr7:86957763-86957843 9.82e-02 80 chr20:32324952-32325032 1.40e-02 80 chr2:240857181-240857261 4.52e-03 31_[+3(7.80e-05)]_41 chr19:35449082-35449162 1.67e-02 67_[+3(7.80e-05)]_5 chr3:128578549-128578629 7.04e-01 80 chr6:118895553-118895633 1.01e-05 40_[+1(1.53e-05)]_8_[+4(7.13e-05)]_\ 16 chr1:12700394-12700474 3.47e-07 5_[+3(3.13e-05)]_17_[+2(6.83e-05)]_\ 6_[+1(1.53e-05)]_28 chr19:42170152-42170232 4.83e-01 80 chr22:22813684-22813764 8.63e-05 25_[+1(1.53e-05)]_9_[+4(7.13e-05)]_\ 30 chr7:158642344-158642424 6.66e-04 23_[+3(4.61e-05)]_49 chr10:17512358-17512438 4.87e-02 80 chr16:3433177-3433257 4.93e-01 80 chr18:77782828-77782908 8.21e-01 80 chr16:89934484-89934564 1.36e-04 51_[+5(1.32e-05)]_21 chr19:11717493-11717573 1.03e-02 30_[+4(3.30e-05)]_42 chr14:50780981-50781061 2.22e-01 80 chr19:48786845-48786925 8.75e-01 80 chr1:151880054-151880134 1.41e-03 13_[+3(7.80e-05)]_59 chr7:94287189-94287269 2.15e-02 80 chr1:12275762-12275842 1.51e-02 70_[+1(8.34e-05)]_2 chr6:18266172-18266252 8.23e-03 37_[+1(5.01e-05)]_35 chr4:84299724-84299804 1.07e-01 80 chr20:36871384-36871464 4.35e-01 80 chr10:65280882-65280962 4.74e-01 80 chr10:94474103-94474183 5.29e-03 61_[+3(9.30e-05)]_11 chr15:80660147-80660227 6.32e-01 80 chr4:1740279-1740359 1.15e-05 40_[+5(1.32e-05)]_[+2(6.83e-05)]_8_\ [+1(1.53e-05)]_8 chr7:46508507-46508587 4.83e-01 80 chr6:83640901-83640981 1.86e-03 22_[+4(3.30e-05)]_19_[+4(3.30e-05)]_\ 3_[+2(6.83e-05)]_12 chr7:64869105-64869185 2.65e-01 80 chr2:129226937-129227017 9.50e-02 80 chr11:13113017-13113097 1.64e-01 80 chr6:68522808-68522888 1.11e-01 80 chr2:12364008-12364088 9.81e-06 22_[+4(3.30e-05)]_3_[+2(6.83e-05)]_\ 19_[+3(1.68e-05)]_12 chr10:72525944-72526024 8.76e-05 8_[+2(6.83e-05)]_5_[+1(6.79e-05)]_6_\ [+3(1.68e-05)]_37 chr3:176723977-176724057 1.68e-03 27_[+3(1.68e-05)]_45 chr2:171780495-171780575 4.15e-01 80 chr7:150687732-150687812 8.02e-03 51_[+3(3.13e-05)]_21 chr4:25225515-25225595 6.27e-02 51_[+3(7.80e-05)]_21 chr6:35876742-35876822 6.45e-05 4_[+2(6.83e-05)]_5_[+1(6.79e-05)]_6_\ [+3(1.68e-05)]_41 chr6:147286408-147286488 2.41e-01 80 chr21:39595992-39596072 1.31e-01 31_[+3(7.80e-05)]_41 chr7:152430515-152430595 3.25e-06 2_[+5(1.32e-05)]_[+2(6.83e-05)]_7_\ [+1(1.53e-05)]_47 chr16:3340131-3340211 1.77e-01 80 chr11:74582239-74582319 2.52e-02 80 chr16:75179537-75179617 4.49e-01 80 chr13:41722995-41723075 3.33e-02 80 chr2:174210968-174211048 2.19e-03 24_[+4(7.13e-05)]_12_[+5(5.89e-05)]_\ 28 chr7:111582830-111582910 7.56e-01 80 chr14:107119921-10712000 1.05e-01 80 chr6:13287531-13287611 7.12e-03 80 chr3:10211047-10211127 3.82e-01 80 chr4:10463064-10463144 8.00e-02 80 chr2:183934061-183934141 7.73e-02 80 chr7:75436047-75436127 1.43e-02 80 chr19:58077949-58078029 9.44e-02 80 chr12:132678763-13267884 5.36e-02 80 chr19:21702438-21702518 1.98e-02 59_[+3(7.80e-05)]_13 chr7:10798949-10799029 2.80e-02 11_[+1(1.53e-05)]_61 chr1:31931307-31931387 1.46e-04 15_[+1(1.53e-05)]_10_[+4(7.13e-05)]_\ 39 chr15:85164961-85165041 4.67e-01 80 chr10:71896933-71897013 9.54e-02 80 chr7:2068526-2068606 5.72e-01 80 chr10:72408368-72408448 4.25e-01 80 chr2:31919125-31919205 8.57e-01 80 chr2:174163426-174163506 2.42e-01 80 chr9:139667921-139668001 3.35e-02 80 chr2:86188281-86188361 5.75e-05 [+1(5.01e-05)]_23_[+3(4.61e-05)]_32_\ [+1(1.53e-05)]_1 chr3:119758638-119758718 6.63e-05 25_[+1(1.53e-05)]_8_[+4(7.13e-05)]_\ 31 chr3:10287080-10287160 8.40e-01 80 chr5:103521905-103521985 5.50e-02 80 chr14:45508256-45508336 6.11e-06 50_[+3(1.68e-05)]_22 chr2:122440435-122440515 1.81e-01 80 chr16:3458778-3458858 1.47e-01 80 chr8:130810795-130810875 4.09e-03 51_[+4(3.30e-05)]_21 chr12:10063563-10063643 3.50e-07 2_[+5(1.32e-05)]_[+2(6.83e-05)]_5_\ [+1(1.53e-05)]_49 chr1:153517482-153517562 3.28e-01 80 chr3:31648093-31648173 2.16e-04 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chr7:128523755-128523835 5.80e-04 80 chr1:192399974-192400054 7.26e-02 80 chr2:119502485-119502565 1.24e-01 80 chr7:149226350-149226430 2.93e-03 80 chr7:99669063-99669143 2.66e-01 80 chr19:11943563-11943643 2.41e-01 80 chr2:171679745-171679825 9.12e-02 80 chr1:212551105-212551185 5.73e-02 80 chr14:107120121-10712020 1.49e-02 80 chr3:142824205-142824285 6.96e-02 80 -------------------------------------------------------------------------------- ******************************************************************************** ******************************************************************************** Stopped because requested number of motifs (5) found. ******************************************************************************** CPU: c22n08.farnam.hpc.yale.internal ********************************************************************************