******************************************************************************** MEME - Motif discovery tool ******************************************************************************** MEME version 5.3.3 (Release date: Sun Feb 7 15:39:52 2021 -0800) For further information on how to interpret these results please access https://meme-suite.org/meme. To get a copy of the MEME Suite software please access https://meme-suite.org. ******************************************************************************** ******************************************************************************** REFERENCE ******************************************************************************** If you use this program in your research, please cite: Timothy L. Bailey and Charles Elkan, "Fitting a mixture model by expectation maximization to discover motifs in biopolymers", Proceedings of the Second International Conference on Intelligent Systems for Molecular Biology, pp. 28-36, AAAI Press, Menlo Park, California, 1994. ******************************************************************************** ******************************************************************************** TRAINING SET ******************************************************************************** PRIMARY SEQUENCES= ../result/final_prediction/K562/fasta/RankLinear0.6_40/SAP30.fasta CONTROL SEQUENCES= --none-- ALPHABET= ACGT Sequence name Weight Length Sequence name Weight Length ------------- ------ ------ ------------- ------ ------ chr6:7312704-7312784 1.0000 80 chr17:1933678-1933758 1.0000 80 chr12:122150789-12215086 1.0000 80 chr1:100435862-100435942 1.0000 80 chr10:95256384-95256464 1.0000 80 chr3:49893861-49893941 1.0000 80 chr10:13203749-13203829 1.0000 80 chr20:42295737-42295817 1.0000 80 chr12:122151009-12215108 1.0000 80 chr15:85524074-85524154 1.0000 80 chr3:20082991-20083071 1.0000 80 chr22:19466342-19466422 1.0000 80 chr2:43822753-43822833 1.0000 80 chr17:1419704-1419784 1.0000 80 chr16:30773253-30773333 1.0000 80 chr4:6785511-6785591 1.0000 80 chr9:139378381-139378461 1.0000 80 chr8:27632104-27632184 1.0000 80 chr3:194392826-194392906 1.0000 80 chr20:3761979-3762059 1.0000 80 chr3:52188330-52188410 1.0000 80 chr19:2785787-2785867 1.0000 80 chr7:137686414-137686494 1.0000 80 chr18:47901475-47901555 1.0000 80 chr6:80714425-80714505 1.0000 80 chr16:4784623-4784703 1.0000 80 chr1:44435931-44436011 1.0000 80 chr4:2243511-2243591 1.0000 80 chr5:172483675-172483755 1.0000 80 chr14:103995601-10399568 1.0000 80 chr4:7044548-7044628 1.0000 80 chr22:31460153-31460233 1.0000 80 chr15:41805904-41805984 1.0000 80 chr4:81256983-81257063 1.0000 80 chrX:152735489-152735569 1.0000 80 chr3:121264686-121264766 1.0000 80 chr16:88773156-88773236 1.0000 80 chr8:117778979-117779059 1.0000 80 chr9:99181361-99181441 1.0000 80 chr16:31045306-31045386 1.0000 80 chr2:230787261-230787341 1.0000 80 chr8:33342905-33342985 1.0000 80 chr3:49966993-49967073 1.0000 80 chr21:33765168-33765248 1.0000 80 chr19:55691529-55691609 1.0000 80 chr10:104001547-10400162 1.0000 80 chr3:14166831-14166911 1.0000 80 chr6:150185062-150185142 1.0000 80 chr1:1821545-1821625 1.0000 80 chr1:229762228-229762308 1.0000 80 chr14:102771364-10277144 1.0000 80 chr15:85143766-85143846 1.0000 80 chr14:105957686-10595776 1.0000 80 chr22:21221607-21221687 1.0000 80 chr7:123174468-123174548 1.0000 80 chr12:125473556-12547363 1.0000 80 chr12:48550952-48551032 1.0000 80 chr10:99160955-99161035 1.0000 80 chr10:70231436-70231516 1.0000 80 chr14:73393244-73393324 1.0000 80 chr9:106856626-106856706 1.0000 80 chr10:43697808-43697888 1.0000 80 chr15:66797665-66797745 1.0000 80 chr3:108308166-108308246 1.0000 80 chr14:106267680-10626776 1.0000 80 chr1:6453325-6453405 1.0000 80 chr4:184427530-184427610 1.0000 80 chr9:131452488-131452568 1.0000 80 chr2:198570132-198570212 1.0000 80 chr11:71159941-71160021 1.0000 80 chr10:26986824-26986904 1.0000 80 chr6:52149273-52149353 1.0000 80 chr3:48229778-48229858 1.0000 80 chr22:51038679-51038759 1.0000 80 chr12:50506169-50506249 1.0000 80 chr12:101674149-10167422 1.0000 80 chr12:49717043-49717123 1.0000 80 chr19:53426249-53426329 1.0000 80 chr7:1498860-1498940 1.0000 80 chr22:21212796-21212876 1.0000 80 chr17:73630124-73630204 1.0000 80 chr9:33473765-33473845 1.0000 80 chr9:131218090-131218170 1.0000 80 chr6:167412458-167412538 1.0000 80 chr10:5726971-5727051 1.0000 80 chr1:161719889-161719969 1.0000 80 chr2:196933444-196933524 1.0000 80 chr4:177116608-177116688 1.0000 80 chr18:77794601-77794681 1.0000 80 chr1:230562402-230562482 1.0000 80 chr19:2165139-2165219 1.0000 80 chr2:173421214-173421294 1.0000 80 chr8:144691429-144691509 1.0000 80 chr10:104474507-10447458 1.0000 80 chr2:68385114-68385194 1.0000 80 chr1:11119483-11119563 1.0000 80 chr21:46961636-46961716 1.0000 80 chr22:21213509-21213589 1.0000 80 chr1:6662444-6662524 1.0000 80 chr15:40886489-40886569 1.0000 80 chr8:22526522-22526602 1.0000 80 chr12:64174043-64174123 1.0000 80 chr11:118272511-11827259 1.0000 80 chr7:133812200-133812280 1.0000 80 chr1:65775582-65775662 1.0000 80 chrX:152735707-152735787 1.0000 80 chr16:50100000-50100080 1.0000 80 chr15:41624544-41624624 1.0000 80 chr8:145743111-145743191 1.0000 80 chr19:49631612-49631692 1.0000 80 chr6:33256890-33256970 1.0000 80 chr8:141474297-141474377 1.0000 80 chr17:42219335-42219415 1.0000 80 chr4:110736949-110737029 1.0000 80 chr1:156542238-156542318 1.0000 80 chr8:145560377-145560457 1.0000 80 chr1:67894846-67894926 1.0000 80 chr4:89514405-89514485 1.0000 80 chr16:87417238-87417318 1.0000 80 chr5:175815511-175815591 1.0000 80 chr19:13002252-13002332 1.0000 80 chr21:47648516-47648596 1.0000 80 chr6:33265957-33266037 1.0000 80 chr4:113557896-113557976 1.0000 80 chr7:139478168-139478248 1.0000 80 chr4:6576986-6577066 1.0000 80 chr1:53792177-53792257 1.0000 80 chr17:4046111-4046191 1.0000 80 chr4:186317945-186318025 1.0000 80 chr19:13002050-13002130 1.0000 80 chr7:99070747-99070827 1.0000 80 chr1:52869960-52870040 1.0000 80 chr13:31040241-31040321 1.0000 80 chr8:27695241-27695321 1.0000 80 chr16:58035105-58035185 1.0000 80 chr7:128865225-128865305 1.0000 80 chr14:31889423-31889503 1.0000 80 chr19:1864282-1864362 1.0000 80 chr22:19166796-19166876 1.0000 80 chr4:178231031-178231111 1.0000 80 chr3:50563572-50563652 1.0000 80 chr18:158909-158989 1.0000 80 chr12:109535656-10953573 1.0000 80 chr16:67193628-67193708 1.0000 80 chr12:100594396-10059447 1.0000 80 chr17:8113818-8113898 1.0000 80 chr17:58217293-58217373 1.0000 80 chr9:139137395-139137475 1.0000 80 chr1:101360609-101360689 1.0000 80 chr14:45605125-45605205 1.0000 80 chr17:58155919-58155999 1.0000 80 chr20:33264727-33264807 1.0000 80 chr9:4792994-4793074 1.0000 80 chr9:95088257-95088337 1.0000 80 chr19:45682086-45682166 1.0000 80 chr22:20105281-20105361 1.0000 80 chr18:39535229-39535309 1.0000 80 chr14:82000019-82000099 1.0000 80 chr1:28845144-28845224 1.0000 80 chr16:58283874-58283954 1.0000 80 chr22:21996705-21996785 1.0000 80 chr13:48611717-48611797 1.0000 80 chr1:156251165-156251245 1.0000 80 chr1:67390406-67390486 1.0000 80 chr6:33359667-33359747 1.0000 80 chr15:41407828-41407908 1.0000 80 chr5:137514993-137515073 1.0000 80 chr7:130791176-130791256 1.0000 80 chr7:65541270-65541350 1.0000 80 chr11:94227281-94227361 1.0000 80 chr15:48624404-48624484 1.0000 80 chr2:17935425-17935505 1.0000 80 chr4:174255953-174256033 1.0000 80 chr11:107436301-10743638 1.0000 80 chr16:4322372-4322452 1.0000 80 chr12:101673945-10167402 1.0000 80 chr19:3185333-3185413 1.0000 80 chr16:84178951-84179031 1.0000 80 chr9:132020903-132020983 1.0000 80 chr15:43810069-43810149 1.0000 80 chr7:65580545-65580625 1.0000 80 chr19:36545853-36545933 1.0000 80 chr3:9792014-9792094 1.0000 80 chr5:137514792-137514872 1.0000 80 chr19:41903161-41903241 1.0000 80 chr1:118471885-118471965 1.0000 80 chr12:110841342-11084142 1.0000 80 chr6:167413125-167413205 1.0000 80 chr17:4458511-4458591 1.0000 80 chr1:45476900-45476980 1.0000 80 chr16:89284205-89284285 1.0000 80 chr10:75911124-75911204 1.0000 80 chr8:41908688-41908768 1.0000 80 chr16:81040221-81040301 1.0000 80 chr7:100450131-100450211 1.0000 80 chr1:26632964-26633044 1.0000 80 chr22:22006537-22006617 1.0000 80 chr20:20033163-20033243 1.0000 80 chr16:29937339-29937419 1.0000 80 chr1:39324769-39324849 1.0000 80 chr2:223520621-223520701 1.0000 80 chr14:105487859-10548793 1.0000 80 chr2:73441467-73441547 1.0000 80 chr1:43424098-43424178 1.0000 80 chr3:52739884-52739964 1.0000 80 chr15:40987432-40987512 1.0000 80 chr1:207818435-207818515 1.0000 80 chr1:211848929-211849009 1.0000 80 chr8:120867889-120867969 1.0000 80 chr18:29523632-29523712 1.0000 80 chr16:4476005-4476085 1.0000 80 chr11:506448-506528 1.0000 80 chr19:19144892-19144972 1.0000 80 chr20:30467647-30467727 1.0000 80 chr11:66057138-66057218 1.0000 80 chr12:64615968-64616048 1.0000 80 chr12:69754055-69754135 1.0000 80 chr6:5260678-5260758 1.0000 80 chr11:119252554-11925263 1.0000 80 chr15:101817397-10181747 1.0000 80 chr21:34100700-34100780 1.0000 80 chr5:99871068-99871148 1.0000 80 chr2:32853285-32853365 1.0000 80 chr17:38255731-38255811 1.0000 80 chr2:170684927-170685007 1.0000 80 chr5:137368179-137368259 1.0000 80 chr6:39082429-39082509 1.0000 80 chr9:111696830-111696910 1.0000 80 chr11:82612791-82612871 1.0000 80 chr19:52408279-52408359 1.0000 80 chr21:34099975-34100055 1.0000 80 chr6:10838591-10838671 1.0000 80 chr22:32058067-32058147 1.0000 80 chr21:44395595-44395675 1.0000 80 chr9:131038077-131038157 1.0000 80 chr19:46195336-46195416 1.0000 80 chr1:28052709-28052789 1.0000 80 chr17:79981417-79981497 1.0000 80 chr10:129924641-12992472 1.0000 80 chr12:122461689-12246176 1.0000 80 chr12:9102040-9102120 1.0000 80 chr19:45394611-45394691 1.0000 80 chr20:10415799-10415879 1.0000 80 chr21:47744255-47744335 1.0000 80 chr9:135545277-135545357 1.0000 80 chr12:122244015-12224409 1.0000 80 chr22:46692799-46692879 1.0000 80 chr11:64511525-64511605 1.0000 80 chr16:89992826-89992906 1.0000 80 chr14:55658204-55658284 1.0000 80 ******************************************************************************** ******************************************************************************** COMMAND LINE SUMMARY ******************************************************************************** This information can also be useful in the event you wish to report a problem with the MEME software. command: meme -oc ../result/final_prediction/K562/inference_raw/MEME/RankLinear0.6_40_SAP30/ -dna -nmotifs 5 -w 8 -maxsize 250000 -nostatus ../result/final_prediction/K562/fasta/RankLinear0.6_40/SAP30.fasta model: mod= zoops nmotifs= 5 evt= inf objective function: em= E-value of product of p-values starts= E-value of product of p-values strands: + width: minw= 8 maxw= 8 nsites: minsites= 2 maxsites= 250 wnsites= 0.8 theta: spmap= uni spfuzz= 0.5 em: prior= dirichlet b= 0.01 maxiter= 50 distance= 1e-05 trim: wg= 11 ws= 1 endgaps= yes data: n= 20000 N= 250 sample: seed= 0 hsfrac= 0 searchsize= 20000 norand= no csites= 1000 Letter frequencies in dataset: A 0.171 C 0.327 G 0.328 T 0.174 Background letter frequencies (from file dataset with add-one prior applied): A 0.171 C 0.327 G 0.328 T 0.174 Background model order: 0 ******************************************************************************** ******************************************************************************** MOTIF AAAGAAAS MEME-1 width = 8 sites = 22 llr = 198 E-value = 4.6e+000 ******************************************************************************** -------------------------------------------------------------------------------- Motif AAAGAAAS MEME-1 Description -------------------------------------------------------------------------------- Simplified A 9a7:77a2 pos.-specific C :::1:::5 probability G 1:39:3:3 matrix T ::::3::: bits 2.5 * * 2.3 * * 2.0 ** * 1.8 ** * Relative 1.5 *** *** Entropy 1.3 *** *** (13.0 bits) 1.0 ******* 0.8 ******* 0.5 ******* 0.3 ******** 0.0 -------- Multilevel AAAGAAAC consensus G TG G sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAAGAAAS MEME-1 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr3:49893861-49893941 56 2.68e-06 CCAGGCAGCC AAAGAAAC TGCTACAGGT chr6:39082429-39082509 41 4.08e-06 CGCGGGCTGG AAAGAAAA TGTCAAAACT chr12:122461689-12246176 71 6.77e-06 GCCCCTGTGC AAAGAAAG AA chr6:5260678-5260758 1 6.77e-06 . AAAGAAAG GCTCCTCCCC chr2:17935425-17935505 52 6.77e-06 TTGCTTGGGT AAAGAAAG AGGACTTTCC chr14:55658204-55658284 14 1.09e-05 AACCAAACAA AAAGTAAA GAACACTCGG chr8:144691429-144691509 45 1.37e-05 CCACGTCAAA AAAGTAAG AGCAAACAGG chr12:69754055-69754135 15 2.40e-05 CGTGGCTGCC AAGGAAAC GGGCGACTCC chr14:45605125-45605205 23 2.40e-05 GTTTTGTGCG AAGGAAAC CGATGGGGAT chr15:40886489-40886569 32 2.40e-05 TTTCCGCTCT AAGGAAAC TCAGAGCGTG chr4:2243511-2243591 13 2.66e-05 CACGCTGACA AAACAAAC GCACAAGCCC chr19:46195336-46195416 64 4.23e-05 ATGAAGACAA AAGGAAAG GCAGTCTGA chr7:139478168-139478248 41 4.23e-05 AACCGACCCG AAAGAGAG CCCCACGCTG chr4:174255953-174256033 17 5.69e-05 TGCTGGCGCT AAGGTAAC AGAAGAGGTC chr4:177116608-177116688 33 5.69e-05 AGCTGTGGCG AAAGTGAC GGTGACTTGT chr11:71159941-71160021 36 5.69e-05 GGAGACCGCC AAAGTGAC ccgagatgga chr19:2165139-2165219 43 6.51e-05 TTTTCGGGGA AAAGTGAA GCAGGCGCTG chr21:44395595-44395675 61 8.07e-05 AACGAAAAAT GAAGAAAC GCGGAGTCTG chr2:68385114-68385194 33 8.07e-05 GCCGACGGGC GAAGAAAC GACAGGCTGA chr17:58155919-58155999 23 8.21e-05 CGCCATCCTG AAACTAAA TCATCAGGCG chr19:3185333-3185413 57 1.13e-04 catatgcaca aaacagac aaaagttttt chr14:102771364-10277144 73 1.33e-04 TGGTCCCTCG AAGGAGAG -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAAGAAAS MEME-1 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr3:49893861-49893941 2.7e-06 55_[+1]_17 chr6:39082429-39082509 4.1e-06 40_[+1]_32 chr12:122461689-12246176 6.8e-06 70_[+1]_2 chr6:5260678-5260758 6.8e-06 [+1]_72 chr2:17935425-17935505 6.8e-06 51_[+1]_21 chr14:55658204-55658284 1.1e-05 13_[+1]_59 chr8:144691429-144691509 1.4e-05 44_[+1]_28 chr12:69754055-69754135 2.4e-05 14_[+1]_58 chr14:45605125-45605205 2.4e-05 22_[+1]_50 chr15:40886489-40886569 2.4e-05 31_[+1]_41 chr4:2243511-2243591 2.7e-05 12_[+1]_60 chr19:46195336-46195416 4.2e-05 63_[+1]_9 chr7:139478168-139478248 4.2e-05 40_[+1]_32 chr4:174255953-174256033 5.7e-05 16_[+1]_56 chr4:177116608-177116688 5.7e-05 32_[+1]_40 chr11:71159941-71160021 5.7e-05 35_[+1]_37 chr19:2165139-2165219 6.5e-05 42_[+1]_30 chr21:44395595-44395675 8.1e-05 60_[+1]_12 chr2:68385114-68385194 8.1e-05 32_[+1]_40 chr17:58155919-58155999 8.2e-05 22_[+1]_50 chr19:3185333-3185413 0.00011 56_[+1]_16 chr14:102771364-10277144 0.00013 72_[+1] -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAAGAAAS MEME-1 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF AAAGAAAS width=8 seqs=22 chr3:49893861-49893941 ( 56) AAAGAAAC 1 chr6:39082429-39082509 ( 41) AAAGAAAA 1 chr12:122461689-12246176 ( 71) AAAGAAAG 1 chr6:5260678-5260758 ( 1) AAAGAAAG 1 chr2:17935425-17935505 ( 52) AAAGAAAG 1 chr14:55658204-55658284 ( 14) AAAGTAAA 1 chr8:144691429-144691509 ( 45) AAAGTAAG 1 chr12:69754055-69754135 ( 15) AAGGAAAC 1 chr14:45605125-45605205 ( 23) AAGGAAAC 1 chr15:40886489-40886569 ( 32) AAGGAAAC 1 chr4:2243511-2243591 ( 13) AAACAAAC 1 chr19:46195336-46195416 ( 64) AAGGAAAG 1 chr7:139478168-139478248 ( 41) AAAGAGAG 1 chr4:174255953-174256033 ( 17) AAGGTAAC 1 chr4:177116608-177116688 ( 33) AAAGTGAC 1 chr11:71159941-71160021 ( 36) AAAGTGAC 1 chr19:2165139-2165219 ( 43) AAAGTGAA 1 chr21:44395595-44395675 ( 61) GAAGAAAC 1 chr2:68385114-68385194 ( 33) GAAGAAAC 1 chr17:58155919-58155999 ( 23) AAACTAAA 1 chr19:3185333-3185413 ( 57) AAACAGAC 1 chr14:102771364-10277144 ( 73) AAGGAGAG 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAAGAAAS MEME-1 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 11.229 E= 4.6e+000 241 -1110 -185 -1110 255 -1110 -1110 -1110 209 -1110 -27 -1110 -1110 -126 139 -1110 200 -1110 -1110 87 209 -1110 -27 -1110 255 -1110 -1110 -1110 9 61 -5 -1110 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAAGAAAS MEME-1 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 22 E= 4.6e+000 0.909091 0.000000 0.090909 0.000000 1.000000 0.000000 0.000000 0.000000 0.727273 0.000000 0.272727 0.000000 0.000000 0.136364 0.863636 0.000000 0.681818 0.000000 0.000000 0.318182 0.727273 0.000000 0.272727 0.000000 1.000000 0.000000 0.000000 0.000000 0.181818 0.500000 0.318182 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAAGAAAS MEME-1 regular expression -------------------------------------------------------------------------------- AA[AG]G[AT][AG]A[CG] -------------------------------------------------------------------------------- Time 5.04 secs. ******************************************************************************** ******************************************************************************** MOTIF AAAACCAA MEME-2 width = 8 sites = 2 llr = 26 E-value = 8.4e+003 ******************************************************************************** -------------------------------------------------------------------------------- Motif AAAACCAA MEME-2 Description -------------------------------------------------------------------------------- Simplified A aaaa::aa pos.-specific C ::::aa:: probability G :::::::: matrix T :::::::: bits 2.5 **** ** 2.3 **** ** 2.0 **** ** 1.8 **** ** Relative 1.5 ******** Entropy 1.3 ******** (18.5 bits) 1.0 ******** 0.8 ******** 0.5 ******** 0.3 ******** 0.0 -------- Multilevel AAAACCAA consensus sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAAACCAA MEME-2 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr18:77794601-77794681 45 2.67e-06 ATTTGCCTCG AAAACCAA GTAATGCGGC chr3:48229778-48229858 55 2.67e-06 CGGGTAGCAG AAAACCAA GCCGACCTAC -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAAACCAA MEME-2 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr18:77794601-77794681 2.7e-06 44_[+2]_28 chr3:48229778-48229858 2.7e-06 54_[+2]_18 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAAACCAA MEME-2 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF AAAACCAA width=8 seqs=2 chr18:77794601-77794681 ( 45) AAAACCAA 1 chr3:48229778-48229858 ( 55) AAAACCAA 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAAACCAA MEME-2 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 13.1555 E= 8.4e+003 254 -765 -765 -765 254 -765 -765 -765 254 -765 -765 -765 254 -765 -765 -765 -765 161 -765 -765 -765 161 -765 -765 254 -765 -765 -765 254 -765 -765 -765 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAAACCAA MEME-2 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 2 E= 8.4e+003 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAAACCAA MEME-2 regular expression -------------------------------------------------------------------------------- AAAACCAA -------------------------------------------------------------------------------- Time 8.83 secs. ******************************************************************************** ******************************************************************************** MOTIF CWGSAGVD MEME-3 width = 8 sites = 59 llr = 423 E-value = 1.0e+004 ******************************************************************************** -------------------------------------------------------------------------------- Motif CWGSAGVD MEME-3 Description -------------------------------------------------------------------------------- Simplified A :4:1a:43 pos.-specific C a::5::4: probability G ::a4:a24 matrix T :6:::::3 bits 2.5 * 2.3 * 2.0 * 1.8 * Relative 1.5 *** ** Entropy 1.3 *** ** (10.3 bits) 1.0 *** ** 0.8 *** ** 0.5 *** **** 0.3 ******** 0.0 -------- Multilevel CTGCAGCG consensus A G AT sequence GA -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CWGSAGVD MEME-3 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr3:20082991-20083071 64 1.02e-05 TCACCTCCAG CTGCAGAT CCAGATGTG chr16:4322372-4322452 6 2.02e-05 GACTG CTGCAGAA CCACGTGGGT chr18:158909-158989 66 2.02e-05 AGTCGTGACT CTGCAGAA TAGTTTC chr10:104474507-10447458 53 2.02e-05 GGACTTCCAC CTGCAGAA GCCACGTGGC chr1:6453325-6453405 72 2.02e-05 CGGCGGGCGG CTGCAGAA G chr4:2243511-2243591 54 2.02e-05 CGACACCGAG CTGCAGAA GACGGGGGTG chr20:3761979-3762059 39 2.02e-05 TTTCTCGCCA CTGCAGAA GCCCATAACT chr21:46961636-46961716 13 5.96e-05 AGACAATGGT CTGGAGAT GTGCCAGGGG chr14:73393244-73393324 67 5.96e-05 CGCGCTCCCG CTGCAGAG CTCGGG chr8:27695241-27695321 24 9.90e-05 CAGCGAGACC CTGCAGCT GCCTCTAGCA chr13:48611717-48611797 34 1.66e-04 CCGCGGACAG CTGGAGAG GCCGAGGCGC chr19:45682086-45682166 49 1.66e-04 TGAGTGCCCC CAGCAGAG TCCAGTCGGA chr19:49631612-49631692 60 1.66e-04 GGAGCAGCTG CTGGAGAG GGAGGAAGAG chr17:73630124-73630204 35 1.66e-04 AGCTGGCTGT CAGCAGAG GAGCTGGGCT chr15:66797665-66797745 34 1.66e-04 CTGAACTGCG CAGCAGAG GACTTTTATT chr12:125473556-12547363 50 1.66e-04 GCGGCCGGAC CAGCAGAG CAATCCGAAA chr12:122244015-12224409 62 2.52e-04 CCCACCCTTC CTGCAGCG TGGGGAGGAC chr20:10415799-10415879 63 2.52e-04 GGCCTCAATC CTGCAGCG AAGCTGCCCA chr17:79981417-79981497 55 2.52e-04 GGCTCCCTTT CAGCAGCT GCGGGAGCAT chr2:32853285-32853365 55 2.52e-04 CCTGTTTTGG CTGCAGCG GTGTCTGGGG chr8:120867889-120867969 29 2.52e-04 AAGTCGCCGG CTGCAGCG CCGCTGGCCC chr20:20033163-20033243 56 2.52e-04 GTGCGGCGTC CTGGAGCT GCGGATGAGG chr13:31040241-31040321 38 2.52e-04 GAGGCAGAGG CAGCAGCT GCTACGGGAA chr5:175815511-175815591 47 2.52e-04 ACCACCGCAC CAGCAGCT CAAACACGCT chr8:22526522-22526602 4 2.52e-04 GTC CAGCAGCT CCCGCCGCCT chr14:106267680-10626776 4 2.52e-04 GGA CAGCAGCT TGGACACCAC chr1:1821545-1821625 51 2.52e-04 CGGGCCTCGG CAGGAGAA GGGCGAGGCC chr21:47744255-47744335 22 3.33e-04 CGCCCCCTGC CAGGAGAG GACGCGGTCC chr11:94227281-94227361 26 3.33e-04 AGGCCGAGCC CTGCAGGT CAGGCCGCTT chr14:82000019-82000099 37 3.33e-04 GCACCGCACA CAGCAGCA GCGTCAGCCC chr16:67193628-67193708 5 3.33e-04 CTGG CTGGAGCA GCCGCCGGTG chr16:58035105-58035185 64 3.33e-04 TGCCGGGAGG CTGCAGGT GACCAGATC chr11:118272511-11827259 43 3.33e-04 GCGGGATGGC CTGCAGGT GGAGGGAGCA chr2:68385114-68385194 65 3.33e-04 CTGTCCGCAG CAGGAGAG GGCGGGGA chr12:49717043-49717123 22 3.33e-04 AAAGTAGCTC CAGCAGCA CCCGAGAGGG chr9:135545277-135545357 69 4.50e-04 ACGCGTGGTG CAGCAGCG AGCC chr1:39324769-39324849 26 4.50e-04 GTAAATGACA CAGGAGCT GGGTCCCAGG chr4:89514405-89514485 59 4.50e-04 GCGGGGGTGT CAGGAGCT GGGACGGCCG chr1:6662444-6662524 44 4.50e-04 CGAGCTGCTG CTGCAGGA AGGCCCCGCA chr22:21221607-21221687 42 4.50e-04 GCCTCGGTAC CTGGAGCG GTTGAGGCCT chr1:229762228-229762308 36 4.50e-04 AGACTCTGGG CTGGAGCG GCTTCGGCAC chr1:44435931-44436011 19 4.50e-04 AGTGTACGAG CTGGAGCG AGTCGCTGGA chr12:122150789-12215086 25 4.50e-04 GTCCGGGCAG CTGGAGCG TTGCGAGCGC chr5:137368179-137368259 6 5.60e-04 AGGGG CTGGAGGT GAGGGGCACG chr21:34100700-34100780 53 5.60e-04 CAGGTGGCGC CTGAAGAG CTGTCCATGG chr6:5260678-5260758 45 5.60e-04 CACCTGTAGG CAGGAGCA CGCTTTTCGA chr7:100450131-100450211 59 5.60e-04 AGACGCTTGT CTGCAGGG CTGCATTGCA chr15:48624404-48624484 55 5.60e-04 ATGCCCTGCT CTGAAGAG ACACCCGCCA chr22:21213509-21213589 69 5.60e-04 CCGCCAGCAC CAGCAGGT CCCT chr6:52149273-52149353 32 5.60e-04 GGCACACGGT CTGGAGGT CTGGCGGGCC chr3:108308166-108308246 21 5.60e-04 GACTGACAGT CAGGAGCA AGGACTTCAA chr3:121264686-121264766 27 5.60e-04 CACTCCGACG CAGAAGAT TCATGGCAAA chr4:81256983-81257063 45 5.60e-04 CTTGTACTAC CTGGAGGT AAGGGCGGAG chr22:21996705-21996785 44 6.49e-04 CGGGTCGGTG CTGAAGCT GCTCAATACG chr2:198570132-198570212 58 6.49e-04 GCTGTCTCTC CTGGAGGA CTTCGGCCCA chr21:34099975-34100055 6 7.62e-04 TGCGC CAGAAGAG ATACCCCGGC chr1:52869960-52870040 54 7.62e-04 TAACCTGCAC CAGCAGGG CTCCTTCTAC chr19:2785787-2785867 5 7.62e-04 CGGG CTGGAGGG GCAGCGGGGG chr5:137514792-137514872 73 8.10e-04 GCCAGTATCC CAGGAGGA -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CWGSAGVD MEME-3 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr3:20082991-20083071 1e-05 63_[+3]_9 chr16:4322372-4322452 2e-05 5_[+3]_67 chr18:158909-158989 2e-05 65_[+3]_7 chr10:104474507-10447458 2e-05 52_[+3]_20 chr1:6453325-6453405 2e-05 71_[+3]_1 chr4:2243511-2243591 2e-05 53_[+3]_19 chr20:3761979-3762059 2e-05 38_[+3]_34 chr21:46961636-46961716 6e-05 12_[+3]_60 chr14:73393244-73393324 6e-05 66_[+3]_6 chr8:27695241-27695321 9.9e-05 23_[+3]_49 chr13:48611717-48611797 0.00017 33_[+3]_39 chr19:45682086-45682166 0.00017 48_[+3]_24 chr19:49631612-49631692 0.00017 59_[+3]_13 chr17:73630124-73630204 0.00017 34_[+3]_38 chr15:66797665-66797745 0.00017 33_[+3]_39 chr12:125473556-12547363 0.00017 49_[+3]_23 chr12:122244015-12224409 0.00025 61_[+3]_11 chr20:10415799-10415879 0.00025 62_[+3]_10 chr17:79981417-79981497 0.00025 54_[+3]_18 chr2:32853285-32853365 0.00025 54_[+3]_18 chr8:120867889-120867969 0.00025 28_[+3]_44 chr20:20033163-20033243 0.00025 55_[+3]_17 chr13:31040241-31040321 0.00025 37_[+3]_35 chr5:175815511-175815591 0.00025 46_[+3]_26 chr8:22526522-22526602 0.00025 3_[+3]_69 chr14:106267680-10626776 0.00025 3_[+3]_69 chr1:1821545-1821625 0.00025 50_[+3]_22 chr21:47744255-47744335 0.00033 21_[+3]_51 chr11:94227281-94227361 0.00033 25_[+3]_47 chr14:82000019-82000099 0.00033 36_[+3]_36 chr16:67193628-67193708 0.00033 4_[+3]_68 chr16:58035105-58035185 0.00033 63_[+3]_9 chr11:118272511-11827259 0.00033 42_[+3]_30 chr2:68385114-68385194 0.00033 64_[+3]_8 chr12:49717043-49717123 0.00033 21_[+3]_51 chr9:135545277-135545357 0.00045 68_[+3]_4 chr1:39324769-39324849 0.00045 25_[+3]_47 chr4:89514405-89514485 0.00045 58_[+3]_14 chr1:6662444-6662524 0.00045 43_[+3]_29 chr22:21221607-21221687 0.00045 41_[+3]_31 chr1:229762228-229762308 0.00045 35_[+3]_37 chr1:44435931-44436011 0.00045 18_[+3]_54 chr12:122150789-12215086 0.00045 24_[+3]_48 chr5:137368179-137368259 0.00056 5_[+3]_67 chr21:34100700-34100780 0.00056 52_[+3]_20 chr6:5260678-5260758 0.00056 44_[+3]_28 chr7:100450131-100450211 0.00056 58_[+3]_14 chr15:48624404-48624484 0.00056 54_[+3]_18 chr22:21213509-21213589 0.00056 68_[+3]_4 chr6:52149273-52149353 0.00056 31_[+3]_41 chr3:108308166-108308246 0.00056 20_[+3]_52 chr3:121264686-121264766 0.00056 26_[+3]_46 chr4:81256983-81257063 0.00056 44_[+3]_28 chr22:21996705-21996785 0.00065 43_[+3]_29 chr2:198570132-198570212 0.00065 57_[+3]_15 chr21:34099975-34100055 0.00076 5_[+3]_67 chr1:52869960-52870040 0.00076 53_[+3]_19 chr19:2785787-2785867 0.00076 4_[+3]_68 chr5:137514792-137514872 0.00081 72_[+3] -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CWGSAGVD MEME-3 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF CWGSAGVD width=8 seqs=59 chr3:20082991-20083071 ( 64) CTGCAGAT 1 chr16:4322372-4322452 ( 6) CTGCAGAA 1 chr18:158909-158989 ( 66) CTGCAGAA 1 chr10:104474507-10447458 ( 53) CTGCAGAA 1 chr1:6453325-6453405 ( 72) CTGCAGAA 1 chr4:2243511-2243591 ( 54) CTGCAGAA 1 chr20:3761979-3762059 ( 39) CTGCAGAA 1 chr21:46961636-46961716 ( 13) CTGGAGAT 1 chr14:73393244-73393324 ( 67) CTGCAGAG 1 chr8:27695241-27695321 ( 24) CTGCAGCT 1 chr13:48611717-48611797 ( 34) CTGGAGAG 1 chr19:45682086-45682166 ( 49) CAGCAGAG 1 chr19:49631612-49631692 ( 60) CTGGAGAG 1 chr17:73630124-73630204 ( 35) CAGCAGAG 1 chr15:66797665-66797745 ( 34) CAGCAGAG 1 chr12:125473556-12547363 ( 50) CAGCAGAG 1 chr12:122244015-12224409 ( 62) CTGCAGCG 1 chr20:10415799-10415879 ( 63) CTGCAGCG 1 chr17:79981417-79981497 ( 55) CAGCAGCT 1 chr2:32853285-32853365 ( 55) CTGCAGCG 1 chr8:120867889-120867969 ( 29) CTGCAGCG 1 chr20:20033163-20033243 ( 56) CTGGAGCT 1 chr13:31040241-31040321 ( 38) CAGCAGCT 1 chr5:175815511-175815591 ( 47) CAGCAGCT 1 chr8:22526522-22526602 ( 4) CAGCAGCT 1 chr14:106267680-10626776 ( 4) CAGCAGCT 1 chr1:1821545-1821625 ( 51) CAGGAGAA 1 chr21:47744255-47744335 ( 22) CAGGAGAG 1 chr11:94227281-94227361 ( 26) CTGCAGGT 1 chr14:82000019-82000099 ( 37) CAGCAGCA 1 chr16:67193628-67193708 ( 5) CTGGAGCA 1 chr16:58035105-58035185 ( 64) CTGCAGGT 1 chr11:118272511-11827259 ( 43) CTGCAGGT 1 chr2:68385114-68385194 ( 65) CAGGAGAG 1 chr12:49717043-49717123 ( 22) CAGCAGCA 1 chr9:135545277-135545357 ( 69) CAGCAGCG 1 chr1:39324769-39324849 ( 26) CAGGAGCT 1 chr4:89514405-89514485 ( 59) CAGGAGCT 1 chr1:6662444-6662524 ( 44) CTGCAGGA 1 chr22:21221607-21221687 ( 42) CTGGAGCG 1 chr1:229762228-229762308 ( 36) CTGGAGCG 1 chr1:44435931-44436011 ( 19) CTGGAGCG 1 chr12:122150789-12215086 ( 25) CTGGAGCG 1 chr5:137368179-137368259 ( 6) CTGGAGGT 1 chr21:34100700-34100780 ( 53) CTGAAGAG 1 chr6:5260678-5260758 ( 45) CAGGAGCA 1 chr7:100450131-100450211 ( 59) CTGCAGGG 1 chr15:48624404-48624484 ( 55) CTGAAGAG 1 chr22:21213509-21213589 ( 69) CAGCAGGT 1 chr6:52149273-52149353 ( 32) CTGGAGGT 1 chr3:108308166-108308246 ( 21) CAGGAGCA 1 chr3:121264686-121264766 ( 27) CAGAAGAT 1 chr4:81256983-81257063 ( 45) CTGGAGGT 1 chr22:21996705-21996785 ( 44) CTGAAGCT 1 chr2:198570132-198570212 ( 58) CTGGAGGA 1 chr21:34099975-34100055 ( 6) CAGAAGAG 1 chr1:52869960-52870040 ( 54) CAGCAGGG 1 chr19:2785787-2785867 ( 5) CTGGAGGG 1 chr5:137514792-137514872 ( 73) CAGGAGGA 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CWGSAGVD MEME-3 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 9.9683 E= 1.0e+004 -1253 161 -1253 -1253 125 -1253 -1253 177 -1253 -1253 161 -1253 -101 73 18 -1253 255 -1253 -1253 -1253 -1253 -1253 161 -1253 112 32 -58 -1253 57 -1253 31 96 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CWGSAGVD MEME-3 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 59 E= 1.0e+004 0.000000 1.000000 0.000000 0.000000 0.406780 0.000000 0.000000 0.593220 0.000000 0.000000 1.000000 0.000000 0.084746 0.542373 0.372881 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.372881 0.406780 0.220339 0.000000 0.254237 0.000000 0.406780 0.338983 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CWGSAGVD MEME-3 regular expression -------------------------------------------------------------------------------- C[TA]G[CG]AG[CAG][GTA] -------------------------------------------------------------------------------- Time 12.61 secs. ******************************************************************************** ******************************************************************************** MOTIF TCAAATCT MEME-4 width = 8 sites = 3 llr = 38 E-value = 1.1e+004 ******************************************************************************** -------------------------------------------------------------------------------- Motif TCAAATCT MEME-4 Description -------------------------------------------------------------------------------- Simplified A ::aaa::: pos.-specific C :a::::a: probability G :::::::: matrix T a::::a:a bits 2.5 * **** * 2.3 * **** * 2.0 * **** * 1.8 * **** * Relative 1.5 ******** Entropy 1.3 ******** (18.4 bits) 1.0 ******** 0.8 ******** 0.5 ******** 0.3 ******** 0.0 -------- Multilevel TCAAATCT consensus sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCAAATCT MEME-4 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr12:100594396-10059447 17 2.82e-06 CACATAGTAG TCAAATCT CGCCACCACA chr8:144691429-144691509 19 2.82e-06 CACGTGTGAC TCAAATCT TCCCGCAGCC chr10:70231436-70231516 66 2.82e-06 GCTCCTTCTT TCAAATCT CCCGCTT -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCAAATCT MEME-4 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr12:100594396-10059447 2.8e-06 16_[+4]_56 chr8:144691429-144691509 2.8e-06 18_[+4]_54 chr10:70231436-70231516 2.8e-06 65_[+4]_7 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCAAATCT MEME-4 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF TCAAATCT width=8 seqs=3 chr12:100594396-10059447 ( 17) TCAAATCT 1 chr8:144691429-144691509 ( 19) TCAAATCT 1 chr10:70231436-70231516 ( 66) TCAAATCT 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCAAATCT MEME-4 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 12.2293 E= 1.1e+004 -823 -823 -823 252 -823 161 -823 -823 254 -823 -823 -823 254 -823 -823 -823 254 -823 -823 -823 -823 -823 -823 252 -823 161 -823 -823 -823 -823 -823 252 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCAAATCT MEME-4 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 3 E= 1.1e+004 0.000000 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCAAATCT MEME-4 regular expression -------------------------------------------------------------------------------- TCAAATCT -------------------------------------------------------------------------------- Time 16.29 secs. ******************************************************************************** ******************************************************************************** MOTIF TAAATDAC MEME-5 width = 8 sites = 4 llr = 48 E-value = 1.0e+004 ******************************************************************************** -------------------------------------------------------------------------------- Motif TAAATDAC MEME-5 Description -------------------------------------------------------------------------------- Simplified A :aaa:3a: pos.-specific C :::::::a probability G :::::5:: matrix T a:::a3:: bits 2.5 ***** * 2.3 ***** * 2.0 ***** * 1.8 ***** * Relative 1.5 ***** ** Entropy 1.3 ***** ** (17.4 bits) 1.0 ***** ** 0.8 ***** ** 0.5 ******** 0.3 ******** 0.0 -------- Multilevel TAAATGAC consensus A sequence T -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TAAATDAC MEME-5 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr1:39324769-39324849 17 2.78e-06 CTCAGTTTCG TAAATGAC ACAGGAGCTG chr10:99160955-99161035 63 2.78e-06 GGAATGAGCT TAAATGAC CGGCTTCCAG chr2:173421214-173421294 48 5.70e-06 GCTGGCGGCG TAAATAAC GGTGGGCGTG chr2:43822753-43822833 3 5.70e-06 AG TAAATTAC ACTCCTCCTA -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TAAATDAC MEME-5 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr1:39324769-39324849 2.8e-06 16_[+5]_56 chr10:99160955-99161035 2.8e-06 62_[+5]_10 chr2:173421214-173421294 5.7e-06 47_[+5]_25 chr2:43822753-43822833 5.7e-06 2_[+5]_70 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TAAATDAC MEME-5 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF TAAATDAC width=8 seqs=4 chr1:39324769-39324849 ( 17) TAAATGAC 1 chr10:99160955-99161035 ( 63) TAAATGAC 1 chr2:173421214-173421294 ( 48) TAAATAAC 1 chr2:43822753-43822833 ( 3) TAAATTAC 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TAAATDAC MEME-5 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 12.1553 E= 1.0e+004 -865 -865 -865 252 255 -865 -865 -865 255 -865 -865 -865 255 -865 -865 -865 -865 -865 -865 252 55 -865 61 52 255 -865 -865 -865 -865 161 -865 -865 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TAAATDAC MEME-5 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 4 E= 1.0e+004 0.000000 0.000000 0.000000 1.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.250000 0.000000 0.500000 0.250000 1.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TAAATDAC MEME-5 regular expression -------------------------------------------------------------------------------- TAAAT[GAT]AC -------------------------------------------------------------------------------- Time 19.96 secs. ******************************************************************************** ******************************************************************************** SUMMARY OF MOTIFS ******************************************************************************** -------------------------------------------------------------------------------- Combined block diagrams: non-overlapping sites with p-value < 0.0001 -------------------------------------------------------------------------------- SEQUENCE NAME COMBINED P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr6:7312704-7312784 1.60e-01 80 chr17:1933678-1933758 3.40e-01 80 chr12:122150789-12215086 8.10e-02 80 chr1:100435862-100435942 2.18e-02 80 chr10:95256384-95256464 6.61e-01 80 chr3:49893861-49893941 4.39e-03 55_[+1(2.68e-06)]_17 chr10:13203749-13203829 2.85e-01 80 chr20:42295737-42295817 7.07e-01 80 chr12:122151009-12215108 5.57e-01 80 chr15:85524074-85524154 5.74e-01 80 chr3:20082991-20083071 1.98e-02 63_[+3(1.02e-05)]_9 chr22:19466342-19466422 5.50e-01 80 chr2:43822753-43822833 2.67e-02 2_[+5(5.70e-06)]_70 chr17:1419704-1419784 9.97e-01 80 chr16:30773253-30773333 3.15e-01 80 chr4:6785511-6785591 9.31e-01 80 chr9:139378381-139378461 6.36e-01 80 chr8:27632104-27632184 3.15e-01 80 chr3:194392826-194392906 9.01e-01 80 chr20:3761979-3762059 2.94e-02 38_[+3(2.02e-05)]_34 chr3:52188330-52188410 9.15e-01 80 chr19:2785787-2785867 1.20e-01 80 chr7:137686414-137686494 7.61e-01 80 chr18:47901475-47901555 4.57e-01 80 chr6:80714425-80714505 5.10e-01 80 chr16:4784623-4784703 8.41e-01 80 chr1:44435931-44436011 3.19e-01 80 chr4:2243511-2243591 7.25e-06 11_[+2(1.37e-05)]_34_[+3(2.02e-05)]_\ 19 chr5:172483675-172483755 2.47e-01 80 chr14:103995601-10399568 9.82e-01 80 chr4:7044548-7044628 8.58e-01 80 chr22:31460153-31460233 1.21e-03 80 chr15:41805904-41805984 3.77e-01 80 chr4:81256983-81257063 5.80e-02 80 chrX:152735489-152735569 1.52e-01 80 chr3:121264686-121264766 2.52e-01 80 chr16:88773156-88773236 6.58e-01 80 chr8:117778979-117779059 8.26e-01 80 chr9:99181361-99181441 9.28e-01 80 chr16:31045306-31045386 2.97e-01 80 chr2:230787261-230787341 4.93e-01 80 chr8:33342905-33342985 9.52e-01 80 chr3:49966993-49967073 4.13e-01 80 chr21:33765168-33765248 8.06e-01 80 chr19:55691529-55691609 9.90e-01 80 chr10:104001547-10400162 4.66e-01 80 chr3:14166831-14166911 9.99e-01 80 chr6:150185062-150185142 8.31e-01 80 chr1:1821545-1821625 2.63e-01 80 chr1:229762228-229762308 1.87e-01 80 chr14:102771364-10277144 1.76e-01 80 chr15:85143766-85143846 9.94e-01 80 chr14:105957686-10595776 6.66e-01 80 chr22:21221607-21221687 7.19e-01 80 chr7:123174468-123174548 1.44e-01 80 chr12:125473556-12547363 1.12e-01 80 chr12:48550952-48551032 1.08e-01 80 chr10:99160955-99161035 3.38e-04 62_[+5(2.78e-06)]_10 chr10:70231436-70231516 2.11e-02 65_[+4(2.82e-06)]_7 chr14:73393244-73393324 8.43e-02 66_[+3(5.96e-05)]_6 chr9:106856626-106856706 7.14e-01 80 chr10:43697808-43697888 8.04e-01 80 chr15:66797665-66797745 6.24e-02 80 chr3:108308166-108308246 1.24e-01 80 chr14:106267680-10626776 3.67e-01 80 chr1:6453325-6453405 1.70e-01 71_[+3(2.02e-05)]_1 chr4:184427530-184427610 1.86e-01 80 chr9:131452488-131452568 6.92e-01 80 chr2:198570132-198570212 7.02e-01 80 chr11:71159941-71160021 3.81e-02 35_[+1(5.69e-05)]_37 chr10:26986824-26986904 9.45e-01 80 chr6:52149273-52149353 7.65e-01 80 chr3:48229778-48229858 2.55e-03 54_[+2(2.67e-06)]_18 chr22:51038679-51038759 9.98e-01 80 chr12:50506169-50506249 4.53e-01 80 chr12:101674149-10167422 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******************************************************************************** Stopped because requested number of motifs (5) found. ******************************************************************************** CPU: c22n05.farnam.hpc.yale.internal ********************************************************************************