******************************************************************************** MEME - Motif discovery tool ******************************************************************************** MEME version 5.3.3 (Release date: Sun Feb 7 15:39:52 2021 -0800) For further information on how to interpret these results please access https://meme-suite.org/meme. To get a copy of the MEME Suite software please access https://meme-suite.org. ******************************************************************************** ******************************************************************************** REFERENCE ******************************************************************************** If you use this program in your research, please cite: Timothy L. Bailey and Charles Elkan, "Fitting a mixture model by expectation maximization to discover motifs in biopolymers", Proceedings of the Second International Conference on Intelligent Systems for Molecular Biology, pp. 28-36, AAAI Press, Menlo Park, California, 1994. ******************************************************************************** ******************************************************************************** TRAINING SET ******************************************************************************** PRIMARY SEQUENCES= ../result/final_prediction/K562/fasta/RankLinear0.6_40/SAFB2.fasta CONTROL SEQUENCES= --none-- ALPHABET= ACGT Sequence name Weight Length Sequence name Weight Length ------------- ------ ------ ------------- ------ ------ chr22:22507161-22507241 1.0000 80 chr21:36251828-36251908 1.0000 80 chr22:22696751-22696831 1.0000 80 chr22:22949258-22949338 1.0000 80 chr22:23204814-23204894 1.0000 80 chr1:145061232-145061312 1.0000 80 chr10:76278424-76278504 1.0000 80 chr22:23173396-23173476 1.0000 80 chr22:21274197-21274277 1.0000 80 chr13:90799327-90799407 1.0000 80 chr9:37803079-37803159 1.0000 80 chr13:91045445-91045525 1.0000 80 chr20:29636358-29636438 1.0000 80 chr8:125827488-125827568 1.0000 80 chr1:59248244-59248324 1.0000 80 chr10:47115648-47115728 1.0000 80 chr7:106144548-106144628 1.0000 80 chr18:23631327-23631407 1.0000 80 chr13:90554597-90554677 1.0000 80 chr8:41347886-41347966 1.0000 80 chr2:184565208-184565288 1.0000 80 chr22:23360877-23360957 1.0000 80 chr22:17281989-17282069 1.0000 80 chr6:26200798-26200878 1.0000 80 chr17:45214266-45214346 1.0000 80 chr22:19419840-19419920 1.0000 80 chr1:168034042-168034122 1.0000 80 chr5:108744287-108744367 1.0000 80 chr1:154531360-154531440 1.0000 80 chr22:23167587-23167667 1.0000 80 chr21:40555343-40555423 1.0000 80 chr22:22251043-22251123 1.0000 80 chr5:137801377-137801457 1.0000 80 chr1:145105413-145105493 1.0000 80 chr22:17289917-17289997 1.0000 80 chr7:111019272-111019352 1.0000 80 chr7:148725675-148725755 1.0000 80 chr8:41866679-41866759 1.0000 80 chr8:22926300-22926380 1.0000 80 chr22:22571641-22571721 1.0000 80 chr1:180773814-180773894 1.0000 80 ******************************************************************************** ******************************************************************************** COMMAND LINE SUMMARY ******************************************************************************** This information can also be useful in the event you wish to report a problem with the MEME software. command: meme -oc ../result/final_prediction/K562/inference_raw/MEME/RankLinear0.6_40_SAFB2/ -dna -nmotifs 5 -w 8 -maxsize 250000 -nostatus ../result/final_prediction/K562/fasta/RankLinear0.6_40/SAFB2.fasta model: mod= zoops nmotifs= 5 evt= inf objective function: em= E-value of product of p-values starts= E-value of product of p-values strands: + width: minw= 8 maxw= 8 nsites: minsites= 2 maxsites= 41 wnsites= 0.8 theta: spmap= uni spfuzz= 0.5 em: prior= dirichlet b= 0.01 maxiter= 50 distance= 1e-05 trim: wg= 11 ws= 1 endgaps= yes data: n= 3280 N= 41 sample: seed= 0 hsfrac= 0 searchsize= 3280 norand= no csites= 1000 Letter frequencies in dataset: A 0.299 C 0.194 G 0.186 T 0.321 Background letter frequencies (from file dataset with add-one prior applied): A 0.299 C 0.194 G 0.186 T 0.321 Background model order: 0 ******************************************************************************** ******************************************************************************** MOTIF CCCCGSGC MEME-1 width = 8 sites = 8 llr = 83 E-value = 3.1e-003 ******************************************************************************** -------------------------------------------------------------------------------- Motif CCCCGSGC MEME-1 Description -------------------------------------------------------------------------------- Simplified A :1:::1:: pos.-specific C a99915:a probability G ::1193a: matrix T :::::1:: bits 2.4 * ** 2.2 * ** 1.9 * *** ** 1.7 ***** ** Relative 1.5 ***** ** Entropy 1.2 ***** ** (14.9 bits) 1.0 ***** ** 0.7 ***** ** 0.5 ******** 0.2 ******** 0.0 -------- Multilevel CCCCGCGC consensus G sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCCCGSGC MEME-1 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr8:22926300-22926380 28 1.84e-06 AGGCCTGGCT CCCCGCGC CTCCCTGGGT chr8:41347886-41347966 19 1.84e-06 CGGAAACAAT CCCCGCGC GGGCGGAAGG chr5:137801377-137801457 20 3.61e-06 GCAGCTCCAG CCCCGGGC TGCACCCCCC chr22:19419840-19419920 35 6.46e-06 GAAGGGAGGA CCCCGAGC CGCGTGAAAC chr7:148725675-148725755 20 1.50e-05 CCGGCACGGA CCGCGCGC GCCTCGGCCG chr21:40555343-40555423 45 1.78e-05 CACGCTCCCT CACCGCGC GGGCAATAAG chr1:154531360-154531440 5 2.30e-05 GTGA CCCGGGGC CTGGGGCTTG chr1:59248244-59248324 41 4.32e-05 GCTGCCGCTG CCCCCTGC CACCGAGGCT -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCCCGSGC MEME-1 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr8:22926300-22926380 1.8e-06 27_[+1]_45 chr8:41347886-41347966 1.8e-06 18_[+1]_54 chr5:137801377-137801457 3.6e-06 19_[+1]_53 chr22:19419840-19419920 6.5e-06 34_[+1]_38 chr7:148725675-148725755 1.5e-05 19_[+1]_53 chr21:40555343-40555423 1.8e-05 44_[+1]_28 chr1:154531360-154531440 2.3e-05 4_[+1]_68 chr1:59248244-59248324 4.3e-05 40_[+1]_32 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCCCGSGC MEME-1 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF CCCCGSGC width=8 seqs=8 chr8:22926300-22926380 ( 28) CCCCGCGC 1 chr8:41347886-41347966 ( 19) CCCCGCGC 1 chr5:137801377-137801457 ( 20) CCCCGGGC 1 chr22:19419840-19419920 ( 35) CCCCGAGC 1 chr7:148725675-148725755 ( 20) CCGCGCGC 1 chr21:40555343-40555423 ( 45) CACCGCGC 1 chr1:154531360-154531440 ( 5) CCCGGGGC 1 chr1:59248244-59248324 ( 41) CCCCCTGC 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCCCGSGC MEME-1 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 2993 bayes= 8.54352 E= 3.1e-003 -965 237 -965 -965 -126 217 -965 -965 -965 217 -57 -965 -965 217 -57 -965 -965 -63 223 -965 -126 137 43 -136 -965 -965 242 -965 -965 237 -965 -965 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCCCGSGC MEME-1 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 8 E= 3.1e-003 0.000000 1.000000 0.000000 0.000000 0.125000 0.875000 0.000000 0.000000 0.000000 0.875000 0.125000 0.000000 0.000000 0.875000 0.125000 0.000000 0.000000 0.125000 0.875000 0.000000 0.125000 0.500000 0.250000 0.125000 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCCCGSGC MEME-1 regular expression -------------------------------------------------------------------------------- CCCCG[CG]GC -------------------------------------------------------------------------------- Time 0.57 secs. ******************************************************************************** ******************************************************************************** MOTIF CCCCGCMC MEME-2 width = 8 sites = 6 llr = 63 E-value = 1.7e+001 ******************************************************************************** -------------------------------------------------------------------------------- Motif CCCCGCMC MEME-2 Description -------------------------------------------------------------------------------- Simplified A :::2::3: pos.-specific C a887:a7a probability G :222a::: matrix T :::::::: bits 2.4 * ** * 2.2 * ** * 1.9 * ** * 1.7 *** ** * Relative 1.5 *** ** * Entropy 1.2 *** **** (15.3 bits) 1.0 ******** 0.7 ******** 0.5 ******** 0.2 ******** 0.0 -------- Multilevel CCCCGCCC consensus A sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCCCGCMC MEME-2 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr5:137801377-137801457 35 1.92e-06 GGCTGCACCC CCCCGCCC CGACACCAGC chr8:41347886-41347966 52 1.92e-06 TCGGCCCTGG CCCCGCCC ACATCATTTC chr21:40555343-40555423 68 4.89e-06 ATAAGTCCCG CCCCGCAC AGGCC chr7:148725675-148725755 52 1.04e-05 GAGTCGGCTC CGCCGCCC TAGGCCCTCC chr8:22926300-22926380 63 2.55e-05 CGTGCCTTTT CCGGGCCC CCGAAGCGGC chr22:19419840-19419920 5 3.00e-05 CGCT CCCAGCAC AGGGCGGGGA -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCCCGCMC MEME-2 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr5:137801377-137801457 1.9e-06 34_[+2]_38 chr8:41347886-41347966 1.9e-06 51_[+2]_21 chr21:40555343-40555423 4.9e-06 67_[+2]_5 chr7:148725675-148725755 1e-05 51_[+2]_21 chr8:22926300-22926380 2.5e-05 62_[+2]_10 chr22:19419840-19419920 3e-05 4_[+2]_68 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCCCGCMC MEME-2 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF CCCCGCMC width=8 seqs=6 chr5:137801377-137801457 ( 35) CCCCGCCC 1 chr8:41347886-41347966 ( 52) CCCCGCCC 1 chr21:40555343-40555423 ( 68) CCCCGCAC 1 chr7:148725675-148725755 ( 52) CGCCGCCC 1 chr8:22926300-22926380 ( 63) CCGGGCCC 1 chr22:19419840-19419920 ( 5) CCCAGCAC 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCCCGCMC MEME-2 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 2993 bayes= 9.40775 E= 1.7e+001 -923 237 -923 -923 -923 210 -16 -923 -923 210 -16 -923 -84 178 -16 -923 -923 -923 242 -923 -923 237 -923 -923 16 178 -923 -923 -923 237 -923 -923 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCCCGCMC MEME-2 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 6 E= 1.7e+001 0.000000 1.000000 0.000000 0.000000 0.000000 0.833333 0.166667 0.000000 0.000000 0.833333 0.166667 0.000000 0.166667 0.666667 0.166667 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.333333 0.666667 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCCCGCMC MEME-2 regular expression -------------------------------------------------------------------------------- CCCCGC[CA]C -------------------------------------------------------------------------------- Time 1.05 secs. ******************************************************************************** ******************************************************************************** MOTIF GCGGGVNC MEME-3 width = 8 sites = 7 llr = 65 E-value = 1.2e+002 ******************************************************************************** -------------------------------------------------------------------------------- Motif GCGGGVNC MEME-3 Description -------------------------------------------------------------------------------- Simplified A :::::33: pos.-specific C 191::33a probability G 9:9aa43: matrix T :1::::1: bits 2.4 ** * 2.2 ** * 1.9 * *** * 1.7 ***** * Relative 1.5 ***** * Entropy 1.2 ***** * (13.4 bits) 1.0 ***** * 0.7 ****** * 0.5 ****** * 0.2 ******** 0.0 -------- Multilevel GCGGGGAC consensus AC sequence CG -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GCGGGVNC MEME-3 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr22:19419840-19419920 16 7.31e-06 CCAGCACAGG GCGGGGAC GGAAGGGAGG chr1:59248244-59248324 62 1.15e-05 CGAGGCTACC GCGGGAGC CACCATGCCT chr21:40555343-40555423 6 1.67e-05 GCGCC GCGGGACC GCACGCCGGC chr8:41347886-41347966 36 1.94e-05 CGGGCGGAAG GCGGGGTC GGCCCTGGCC chr8:22926300-22926380 9 3.29e-05 TTGGGGAC CCGGGGCC CAGGCCTGGC chr7:148725675-148725755 9 7.76e-05 AGACTGAC GCCGGCAC GGACCGCGCG chr1:154531360-154531440 28 7.76e-05 GCTTGCCTCT GTGGGCGC CTCAGTGCGA -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GCGGGVNC MEME-3 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr22:19419840-19419920 7.3e-06 15_[+3]_57 chr1:59248244-59248324 1.2e-05 61_[+3]_11 chr21:40555343-40555423 1.7e-05 5_[+3]_67 chr8:41347886-41347966 1.9e-05 35_[+3]_37 chr8:22926300-22926380 3.3e-05 8_[+3]_64 chr7:148725675-148725755 7.8e-05 8_[+3]_64 chr1:154531360-154531440 7.8e-05 27_[+3]_45 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GCGGGVNC MEME-3 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF GCGGGVNC width=8 seqs=7 chr22:19419840-19419920 ( 16) GCGGGGAC 1 chr1:59248244-59248324 ( 62) GCGGGAGC 1 chr21:40555343-40555423 ( 6) GCGGGACC 1 chr8:41347886-41347966 ( 36) GCGGGGTC 1 chr8:22926300-22926380 ( 9) CCGGGGCC 1 chr7:148725675-148725755 ( 9) GCCGGCAC 1 chr1:154531360-154531440 ( 28) GTGGGCGC 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GCGGGVNC MEME-3 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 2993 bayes= 9.34352 E= 1.2e+002 -945 -44 220 -945 -945 214 -945 -117 -945 -44 220 -945 -945 -945 242 -945 -945 -945 242 -945 -7 56 120 -945 -7 56 62 -117 -945 237 -945 -945 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GCGGGVNC MEME-3 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 7 E= 1.2e+002 0.000000 0.142857 0.857143 0.000000 0.000000 0.857143 0.000000 0.142857 0.000000 0.142857 0.857143 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.285714 0.285714 0.428571 0.000000 0.285714 0.285714 0.285714 0.142857 0.000000 1.000000 0.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GCGGGVNC MEME-3 regular expression -------------------------------------------------------------------------------- GCGGG[GAC][ACG]C -------------------------------------------------------------------------------- Time 1.54 secs. ******************************************************************************** ******************************************************************************** MOTIF CTGGGGCW MEME-4 width = 8 sites = 6 llr = 57 E-value = 4.7e+002 ******************************************************************************** -------------------------------------------------------------------------------- Motif CTGGGGCW MEME-4 Description -------------------------------------------------------------------------------- Simplified A ::::::25 pos.-specific C a:::227: probability G ::aa8822 matrix T :a:::::3 bits 2.4 * ** 2.2 * ** 1.9 * ** 1.7 ****** Relative 1.5 ****** Entropy 1.2 ****** (13.8 bits) 1.0 ******* 0.7 ******* 0.5 ******* 0.2 ******** 0.0 -------- Multilevel CTGGGGCA consensus T sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTGGGGCW MEME-4 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr10:47115648-47115728 33 4.32e-06 tggaccatat ctggggca gaaaacaagt chr1:154531360-154531440 13 8.97e-06 GACCCGGGGC CTGGGGCT TGCCTCTGTG chr5:108744287-108744367 51 1.58e-05 TGGAGTGGGA CTGGGGGA TGAAAAGAAA chr22:23167587-23167667 10 3.59e-05 cagagtaca ctggggaa agtttaaatg chr1:59248244-59248324 14 4.82e-05 GCTGTGCAGG CTGGCGCT GAAGCCGCCG chr8:22926300-22926380 47 6.10e-05 TCCCTGGGTC CTGGGCCG TGCCTTTTCC -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTGGGGCW MEME-4 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr10:47115648-47115728 4.3e-06 32_[+4]_40 chr1:154531360-154531440 9e-06 12_[+4]_60 chr5:108744287-108744367 1.6e-05 50_[+4]_22 chr22:23167587-23167667 3.6e-05 9_[+4]_63 chr1:59248244-59248324 4.8e-05 13_[+4]_59 chr8:22926300-22926380 6.1e-05 46_[+4]_26 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTGGGGCW MEME-4 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF CTGGGGCW width=8 seqs=6 chr10:47115648-47115728 ( 33) CTGGGGCA 1 chr1:154531360-154531440 ( 13) CTGGGGCT 1 chr5:108744287-108744367 ( 51) CTGGGGGA 1 chr22:23167587-23167667 ( 10) CTGGGGAA 1 chr1:59248244-59248324 ( 14) CTGGCGCT 1 chr8:22926300-22926380 ( 47) CTGGGCCG 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTGGGGCW MEME-4 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 2993 bayes= 9.40775 E= 4.7e+002 -923 237 -923 -923 -923 -923 -923 164 -923 -923 242 -923 -923 -923 242 -923 -923 -22 216 -923 -923 -22 216 -923 -84 178 -16 -923 74 -923 -16 5 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTGGGGCW MEME-4 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 6 E= 4.7e+002 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.166667 0.833333 0.000000 0.000000 0.166667 0.833333 0.000000 0.166667 0.666667 0.166667 0.000000 0.500000 0.000000 0.166667 0.333333 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTGGGGCW MEME-4 regular expression -------------------------------------------------------------------------------- CTGGGGC[AT] -------------------------------------------------------------------------------- Time 2.03 secs. ******************************************************************************** ******************************************************************************** MOTIF GTGGGWGG MEME-5 width = 8 sites = 2 llr = 23 E-value = 1.2e+003 ******************************************************************************** -------------------------------------------------------------------------------- Motif GTGGGWGG MEME-5 Description -------------------------------------------------------------------------------- Simplified A :::::5:: pos.-specific C :::::::: probability G a:aaa:aa matrix T :a:::5:: bits 2.4 * *** ** 2.2 * *** ** 1.9 * *** ** 1.7 ***** ** Relative 1.5 ***** ** Entropy 1.2 ***** ** (16.9 bits) 1.0 ***** ** 0.7 ******** 0.5 ******** 0.2 ******** 0.0 -------- Multilevel GTGGGAGG consensus T sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GTGGGWGG MEME-5 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr22:17289917-17289997 32 3.97e-06 GTTAAAAAAA GTGGGAGG GAAGAAGCAG chr7:106144548-106144628 23 8.24e-06 ttttaaaaat gtgggtgg tgggtatgta -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GTGGGWGG MEME-5 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr22:17289917-17289997 4e-06 31_[+5]_41 chr7:106144548-106144628 8.2e-06 22_[+5]_50 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GTGGGWGG MEME-5 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF GTGGGWGG width=8 seqs=2 chr22:17289917-17289997 ( 32) GTGGGAGG 1 chr7:106144548-106144628 ( 23) GTGGGTGG 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GTGGGWGG MEME-5 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 2993 bayes= 10.5464 E= 1.2e+003 -765 -765 242 -765 -765 -765 -765 163 -765 -765 242 -765 -765 -765 242 -765 -765 -765 242 -765 74 -765 -765 64 -765 -765 242 -765 -765 -765 242 -765 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GTGGGWGG MEME-5 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 2 E= 1.2e+003 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.500000 0.000000 0.000000 0.500000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GTGGGWGG MEME-5 regular expression -------------------------------------------------------------------------------- GTGGG[AT]GG -------------------------------------------------------------------------------- Time 2.50 secs. ******************************************************************************** ******************************************************************************** SUMMARY OF MOTIFS ******************************************************************************** -------------------------------------------------------------------------------- Combined block diagrams: non-overlapping sites with p-value < 0.0001 -------------------------------------------------------------------------------- SEQUENCE NAME COMBINED P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr22:22507161-22507241 1.00e+00 80 chr21:36251828-36251908 9.13e-01 80 chr22:22696751-22696831 1.00e+00 80 chr22:22949258-22949338 9.16e-01 80 chr22:23204814-23204894 9.70e-01 80 chr1:145061232-145061312 1.00e+00 80 chr10:76278424-76278504 1.00e+00 80 chr22:23173396-23173476 5.03e-01 80 chr22:21274197-21274277 7.24e-01 80 chr13:90799327-90799407 9.18e-01 80 chr9:37803079-37803159 8.90e-01 80 chr13:91045445-91045525 1.00e+00 80 chr20:29636358-29636438 9.98e-01 80 chr8:125827488-125827568 7.75e-02 80 chr1:59248244-59248324 1.42e-07 13_[+4(4.82e-05)]_19_[+1(4.32e-05)]_\ 13_[+3(1.15e-05)]_11 chr10:47115648-47115728 9.85e-03 32_[+4(4.32e-06)]_40 chr7:106144548-106144628 7.23e-02 22_[+5(8.24e-06)]_50 chr18:23631327-23631407 9.76e-01 80 chr13:90554597-90554677 9.98e-01 80 chr8:41347886-41347966 1.97e-09 18_[+1(1.84e-06)]_9_[+3(1.94e-05)]_\ 8_[+2(1.92e-06)]_21 chr2:184565208-184565288 1.00e+00 80 chr22:23360877-23360957 1.00e+00 80 chr22:17281989-17282069 8.81e-01 80 chr6:26200798-26200878 9.98e-01 80 chr17:45214266-45214346 8.20e-01 80 chr22:19419840-19419920 7.26e-08 4_[+2(3.00e-05)]_3_[+3(7.31e-06)]_\ 11_[+1(6.46e-06)]_38 chr1:168034042-168034122 1.00e+00 80 chr5:108744287-108744367 7.58e-03 50_[+4(1.58e-05)]_22 chr1:154531360-154531440 8.79e-08 4_[+1(2.30e-05)]_[+4(8.97e-06)]_7_\ [+3(7.76e-05)]_45 chr22:23167587-23167667 3.56e-02 9_[+4(3.59e-05)]_63 chr21:40555343-40555423 4.39e-07 5_[+3(1.67e-05)]_31_[+1(1.78e-05)]_\ 15_[+2(4.89e-06)]_5 chr22:22251043-22251123 8.96e-01 80 chr5:137801377-137801457 9.48e-06 19_[+1(3.61e-06)]_7_[+2(1.92e-06)]_\ 38 chr1:145105413-145105493 1.00e+00 80 chr22:17289917-17289997 1.86e-02 31_[+5(3.97e-06)]_41 chr7:111019272-111019352 1.00e+00 80 chr7:148725675-148725755 4.69e-06 8_[+3(7.76e-05)]_3_[+1(1.50e-05)]_\ 24_[+2(1.04e-05)]_21 chr8:41866679-41866759 7.81e-01 80 chr8:22926300-22926380 2.35e-08 7_[+1(2.30e-05)]_12_[+1(1.84e-06)]_\ 11_[+4(6.10e-05)]_8_[+2(2.55e-05)]_10 chr22:22571641-22571721 9.92e-01 80 chr1:180773814-180773894 1.00e+00 80 -------------------------------------------------------------------------------- ******************************************************************************** ******************************************************************************** Stopped because requested number of motifs (5) found. ******************************************************************************** CPU: c22n08.farnam.hpc.yale.internal ********************************************************************************