******************************************************************************** MEME - Motif discovery tool ******************************************************************************** MEME version 5.3.3 (Release date: Sun Feb 7 15:39:52 2021 -0800) For further information on how to interpret these results please access https://meme-suite.org/meme. To get a copy of the MEME Suite software please access https://meme-suite.org. ******************************************************************************** ******************************************************************************** REFERENCE ******************************************************************************** If you use this program in your research, please cite: Timothy L. Bailey and Charles Elkan, "Fitting a mixture model by expectation maximization to discover motifs in biopolymers", Proceedings of the Second International Conference on Intelligent Systems for Molecular Biology, pp. 28-36, AAAI Press, Menlo Park, California, 1994. ******************************************************************************** ******************************************************************************** TRAINING SET ******************************************************************************** PRIMARY SEQUENCES= ../result/final_prediction/K562/fasta/RankLinear0.6_40/RUNX1.fasta CONTROL SEQUENCES= --none-- ALPHABET= ACGT Sequence name Weight Length Sequence name Weight Length ------------- ------ ------ ------------- ------ ------ chr10:5593769-5593849 1.0000 80 chr5:74677418-74677498 1.0000 80 chr17:4110422-4110502 1.0000 80 chr1:165362392-165362472 1.0000 80 chr11:120215191-12021527 1.0000 80 chr7:127684242-127684322 1.0000 80 chr14:100288194-10028827 1.0000 80 chr2:109830637-109830717 1.0000 80 chr8:142046309-142046389 1.0000 80 chr6:170404951-170405031 1.0000 80 chr1:246588567-246588647 1.0000 80 chr22:19969518-19969598 1.0000 80 chr8:42074684-42074764 1.0000 80 chr1:16478045-16478125 1.0000 80 chr9:126817218-126817298 1.0000 80 chr9:111539305-111539385 1.0000 80 chr2:197324418-197324498 1.0000 80 chr6:90031434-90031514 1.0000 80 chr3:130506665-130506745 1.0000 80 chrX:48794395-48794475 1.0000 80 chr7:142506649-142506729 1.0000 80 chr20:47654647-47654727 1.0000 80 chr10:82532454-82532534 1.0000 80 chr11:72526278-72526358 1.0000 80 chr7:155102380-155102460 1.0000 80 chr19:8634117-8634197 1.0000 80 chr3:5796488-5796568 1.0000 80 chr5:55788787-55788867 1.0000 80 chr22:22053371-22053451 1.0000 80 chr11:46358479-46358559 1.0000 80 chr17:47438816-47438896 1.0000 80 chr9:101002920-101003000 1.0000 80 chr7:91763135-91763215 1.0000 80 chr13:114035492-11403557 1.0000 80 chr1:101251434-101251514 1.0000 80 chr17:36572790-36572870 1.0000 80 chr22:23197983-23198063 1.0000 80 chr8:74660219-74660299 1.0000 80 chr17:72711397-72711477 1.0000 80 chr3:13049195-13049275 1.0000 80 chr6:2974088-2974168 1.0000 80 chr17:25871771-25871851 1.0000 80 chr22:23226273-23226353 1.0000 80 chr2:232410376-232410456 1.0000 80 chr22:21804773-21804853 1.0000 80 chr22:23088302-23088382 1.0000 80 chr4:6927285-6927365 1.0000 80 chr10:100538206-10053828 1.0000 80 chr22:22937138-22937218 1.0000 80 chr2:54798219-54798299 1.0000 80 chr3:126627725-126627805 1.0000 80 chr12:110531903-11053198 1.0000 80 chr6:71021976-71022056 1.0000 80 chrX:153946223-153946303 1.0000 80 chr5:52839380-52839460 1.0000 80 chr2:121049509-121049589 1.0000 80 chr11:70270384-70270464 1.0000 80 chr5:66502916-66502996 1.0000 80 chr7:150674126-150674206 1.0000 80 chr2:20624732-20624812 1.0000 80 chr19:54714723-54714803 1.0000 80 chr9:124813831-124813911 1.0000 80 chr2:64582049-64582129 1.0000 80 chr1:218550823-218550903 1.0000 80 chr3:155546441-155546521 1.0000 80 chr8:141640633-141640713 1.0000 80 chr6:107268390-107268470 1.0000 80 chr11:65195939-65196019 1.0000 80 chr6:2752292-2752372 1.0000 80 chr12:94483804-94483884 1.0000 80 chr11:18715085-18715165 1.0000 80 chr22:23378951-23379031 1.0000 80 chr17:57920555-57920635 1.0000 80 chr16:69899741-69899821 1.0000 80 chr19:41769058-41769138 1.0000 80 chr6:34530798-34530878 1.0000 80 chr11:113953644-11395372 1.0000 80 chr10:127293925-12729400 1.0000 80 chr12:90127536-90127616 1.0000 80 chr22:22465844-22465924 1.0000 80 chr16:85411516-85411596 1.0000 80 chr22:19629750-19629830 1.0000 80 chr11:33906983-33907063 1.0000 80 chr19:33162868-33162948 1.0000 80 chr21:43885725-43885805 1.0000 80 chr8:30031471-30031551 1.0000 80 chr11:124146166-12414624 1.0000 80 chr6:25974324-25974404 1.0000 80 chr22:36864185-36864265 1.0000 80 chr9:139129834-139129914 1.0000 80 chr17:56406893-56406973 1.0000 80 chr1:24648870-24648950 1.0000 80 chr22:23006443-23006523 1.0000 80 chr19:5691653-5691733 1.0000 80 chr15:70384458-70384538 1.0000 80 chr16:9085987-9086067 1.0000 80 chr12:113646077-11364615 1.0000 80 chr22:23262435-23262515 1.0000 80 chr1:95100667-95100747 1.0000 80 chr3:47388853-47388933 1.0000 80 chr11:876042-876122 1.0000 80 chr17:40903161-40903241 1.0000 80 chr8:21366960-21367040 1.0000 80 chr1:8918312-8918392 1.0000 80 chr3:32750982-32751062 1.0000 80 chr22:20749318-20749398 1.0000 80 chr3:167659496-167659576 1.0000 80 chr7:50626284-50626364 1.0000 80 chr12:122087925-12208800 1.0000 80 chr1:207989323-207989403 1.0000 80 chr3:24561738-24561818 1.0000 80 chr22:39632592-39632672 1.0000 80 chr10:49676378-49676458 1.0000 80 chr19:12886465-12886545 1.0000 80 chr10:6515514-6515594 1.0000 80 chr15:80446410-80446490 1.0000 80 chr10:105264217-10526429 1.0000 80 chr19:11244012-11244092 1.0000 80 chr2:16931603-16931683 1.0000 80 chr2:17314469-17314549 1.0000 80 chr1:145443031-145443111 1.0000 80 chr19:39872629-39872709 1.0000 80 chr5:10284223-10284303 1.0000 80 chr5:95220395-95220475 1.0000 80 chr16:75109231-75109311 1.0000 80 chr6:28534094-28534174 1.0000 80 chr6:16224773-16224853 1.0000 80 chr20:30263251-30263331 1.0000 80 chr1:222885479-222885559 1.0000 80 chr5:55457907-55457987 1.0000 80 chr6:43855888-43855968 1.0000 80 chr12:65114778-65114858 1.0000 80 chr6:52166274-52166354 1.0000 80 chr22:43659962-43660042 1.0000 80 chr22:22385028-22385108 1.0000 80 chr1:12043659-12043739 1.0000 80 chr22:20255925-20256005 1.0000 80 chr4:140187965-140188045 1.0000 80 chr3:141765327-141765407 1.0000 80 chr17:74381731-74381811 1.0000 80 chr6:17600487-17600567 1.0000 80 chr15:50552894-50552974 1.0000 80 chr17:56413377-56413457 1.0000 80 chr22:23252961-23253041 1.0000 80 chr10:96059364-96059444 1.0000 80 chr2:133015192-133015272 1.0000 80 chr13:22562089-22562169 1.0000 80 chr1:19239671-19239751 1.0000 80 chrX:153031114-153031194 1.0000 80 chr5:10708849-10708929 1.0000 80 chrX:107801625-107801705 1.0000 80 chr19:39048048-39048128 1.0000 80 chr19:8569207-8569287 1.0000 80 chr5:131450384-131450464 1.0000 80 chr1:206908993-206909073 1.0000 80 chr11:65194724-65194804 1.0000 80 chr22:23450841-23450921 1.0000 80 chr17:40932222-40932302 1.0000 80 chr22:22313504-22313584 1.0000 80 chr22:20941634-20941714 1.0000 80 chr6:15211463-15211543 1.0000 80 chr22:20285391-20285471 1.0000 80 chr1:8686608-8686688 1.0000 80 chr1:220081003-220081083 1.0000 80 chr3:16977887-16977967 1.0000 80 chr20:46008628-46008708 1.0000 80 chr5:133268509-133268589 1.0000 80 chr15:89545664-89545744 1.0000 80 chr10:76995161-76995241 1.0000 80 chr2:152991634-152991714 1.0000 80 chr4:79542717-79542797 1.0000 80 chr7:26228401-26228481 1.0000 80 chr17:56743872-56743952 1.0000 80 chr3:45615766-45615846 1.0000 80 chr1:148604888-148604968 1.0000 80 chr1:22743214-22743294 1.0000 80 chr1:162342672-162342752 1.0000 80 chr6:2543230-2543310 1.0000 80 chr1:16469982-16470062 1.0000 80 chr10:43911139-43911219 1.0000 80 chr3:185694888-185694968 1.0000 80 chr17:31298336-31298416 1.0000 80 chr7:765349-765429 1.0000 80 chr11:61731347-61731427 1.0000 80 chr1:28199502-28199582 1.0000 80 chr6:28303865-28303945 1.0000 80 chr22:23449902-23449982 1.0000 80 chr1:206274320-206274400 1.0000 80 chr7:104771655-104771735 1.0000 80 chr11:61687769-61687849 1.0000 80 chr22:23239670-23239750 1.0000 80 chr22:19006740-19006820 1.0000 80 chr21:46494119-46494199 1.0000 80 chr22:20885053-20885133 1.0000 80 chr20:3890858-3890938 1.0000 80 chr1:234866552-234866632 1.0000 80 chr7:135335818-135335898 1.0000 80 chr6:36922157-36922237 1.0000 80 chr10:105378630-10537871 1.0000 80 chr1:172715569-172715649 1.0000 80 chr1:27371246-27371326 1.0000 80 chr1:12263819-12263899 1.0000 80 chr3:133175004-133175084 1.0000 80 chr1:3691505-3691585 1.0000 80 chr22:36876218-36876298 1.0000 80 chr19:41104593-41104673 1.0000 80 chr2:15870767-15870847 1.0000 80 chr1:19147274-19147354 1.0000 80 chr6:43804457-43804537 1.0000 80 chr7:139935114-139935194 1.0000 80 chr6:13355811-13355891 1.0000 80 chr16:66558871-66558951 1.0000 80 chr22:20144562-20144642 1.0000 80 chr2:169952261-169952341 1.0000 80 chr7:151092670-151092750 1.0000 80 chr3:141348933-141349013 1.0000 80 chr2:30476947-30477027 1.0000 80 chr15:82237467-82237547 1.0000 80 chr12:4430057-4430137 1.0000 80 chr7:142502496-142502576 1.0000 80 chr11:46563394-46563474 1.0000 80 chr17:39834958-39835038 1.0000 80 chr16:58299539-58299619 1.0000 80 chr3:133472785-133472865 1.0000 80 chr22:22454821-22454901 1.0000 80 chr1:201123014-201123094 1.0000 80 chr15:39432277-39432357 1.0000 80 chr6:13381100-13381180 1.0000 80 chr22:20810690-20810770 1.0000 80 chr1:247711569-247711649 1.0000 80 chr11:63862129-63862209 1.0000 80 chr2:159986996-159987076 1.0000 80 chr5:177844567-177844647 1.0000 80 chr14:100609049-10060912 1.0000 80 chr4:122911797-122911877 1.0000 80 chr3:131514381-131514461 1.0000 80 chr11:62618969-62619049 1.0000 80 chr12:53764905-53764985 1.0000 80 chr21:46494996-46495076 1.0000 80 chr17:60996882-60996962 1.0000 80 chr15:70740421-70740501 1.0000 80 chr9:139568717-139568797 1.0000 80 chr22:19183448-19183528 1.0000 80 chr18:11925946-11926026 1.0000 80 chr7:101372839-101372919 1.0000 80 chr6:43753137-43753217 1.0000 80 chr2:28578546-28578626 1.0000 80 chr10:43264390-43264470 1.0000 80 chr1:11847431-11847511 1.0000 80 chr19:49939935-49940015 1.0000 80 ******************************************************************************** ******************************************************************************** COMMAND LINE SUMMARY ******************************************************************************** This information can also be useful in the event you wish to report a problem with the MEME software. command: meme -oc ../result/final_prediction/K562/inference_raw/MEME/RankLinear0.6_40_RUNX1/ -dna -nmotifs 5 -w 8 -maxsize 250000 -nostatus ../result/final_prediction/K562/fasta/RankLinear0.6_40/RUNX1.fasta model: mod= zoops nmotifs= 5 evt= inf objective function: em= E-value of product of p-values starts= E-value of product of p-values strands: + width: minw= 8 maxw= 8 nsites: minsites= 2 maxsites= 250 wnsites= 0.8 theta: spmap= uni spfuzz= 0.5 em: prior= dirichlet b= 0.01 maxiter= 50 distance= 1e-05 trim: wg= 11 ws= 1 endgaps= yes data: n= 20000 N= 250 sample: seed= 0 hsfrac= 0 searchsize= 20000 norand= no csites= 1000 Letter frequencies in dataset: A 0.229 C 0.275 G 0.276 T 0.22 Background letter frequencies (from file dataset with add-one prior applied): A 0.229 C 0.275 G 0.276 T 0.22 Background model order: 0 ******************************************************************************** ******************************************************************************** MOTIF WRACCACA MEME-1 width = 8 sites = 124 llr = 897 E-value = 1.4e-062 ******************************************************************************** -------------------------------------------------------------------------------- Motif WRACCACA MEME-1 Description -------------------------------------------------------------------------------- Simplified A 468::8:9 pos.-specific C 21:aa:a: probability G 142::2:: matrix T 4::::::1 bits 2.2 2.0 * 1.7 ** * 1.5 *** ** Relative 1.3 *** ** Entropy 1.1 ****** (10.4 bits) 0.9 ****** 0.7 ******* 0.4 ******* 0.2 ******** 0.0 -------- Multilevel TAACCACA consensus AG sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif WRACCACA MEME-1 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr2:169952261-169952341 23 1.26e-05 GTGACTCAGC TAACCACA AATGTCTCCT chr12:122087925-12208800 59 1.26e-05 TCACAGTAAC TAACcaca gtaaccccag chr9:139129834-139129914 56 1.26e-05 agctcacgag taaccaca gagcctgggc chr22:36864185-36864265 16 1.26e-05 CTTCCTCCCT TAACCACA AGACTGACTC chr21:43885725-43885805 53 1.26e-05 ACCACCACCA TAACCACA AAATGCTGTG chr1:218550823-218550903 19 1.26e-05 AAAATGTGGT TAACCACA AGGGCATCCC chr19:54714723-54714803 37 1.26e-05 TGGTTAACCA TAACCACA CTCCAGCGTG chr6:71021976-71022056 18 1.26e-05 GCCAACCACC TAACCACA AAACCACAAA chr11:72526278-72526358 50 1.26e-05 GTTGGAAGTC TAACCACA ATCCCTGCGG chr14:100288194-10028827 10 1.26e-05 TTCTGTGGC TAACCACA GACCACTGGC chr17:4110422-4110502 34 1.26e-05 ccgacccgtc taaccaca gagggcccga chr10:43264390-43264470 23 2.57e-05 gcatgaccat aaaccaca aatgacatct chr5:177844567-177844647 15 2.57e-05 ATACAGCAGA AAACCACA GGATCCATAT chr2:30476947-30477027 61 2.57e-05 tggttgcctg aaaccaca gataatacca chr3:185694888-185694968 21 2.57e-05 TCCAGCCACA AAACCACA TCTGGTTATC chr15:89545664-89545744 62 2.57e-05 CAGTCGCCAG AAACCACA GCACTTCCGC chr1:220081003-220081083 57 2.57e-05 GGTGAGAAGG AAACCACA GTGACAGGCT chr5:131450384-131450464 72 2.57e-05 tagtccaccc aaaccaca t chr10:96059364-96059444 48 2.57e-05 GCTGAACCAC AAACCACA GTATGGCCTT chr1:207989323-207989403 73 2.57e-05 TGTGGTCACA AAACCACA chr12:113646077-11364615 54 2.57e-05 GTGGCTGCAG AAACCACA ACTGTTGACA chr16:69899741-69899821 64 2.57e-05 tgctgtgtgg aaaccaca aaagggaag chr11:18715085-18715165 38 2.57e-05 GCAGGGAACG AAACCACA AAACCCACAG chr17:72711397-72711477 55 2.57e-05 TTTGCACAGA AAACCACA GCAGCTGATA chr3:5796488-5796568 51 2.57e-05 gcccagggcc aaaccaca aactgttgtc chr8:42074684-42074764 48 2.57e-05 GTGGCAAGTG AAACCACA GATAAGCAGG chr2:109830637-109830717 55 2.57e-05 tttatgggta aaaccaca agagataaga chr5:74677418-74677498 28 2.57e-05 AAATTGTGGT AAACCACA GAGGTTTGGC chr11:63862129-63862209 51 4.08e-05 TCAGGGAGGC TGACCACA GAGGCCAGAG chr4:79542717-79542797 2 4.08e-05 c tgaccaca cttgggtcag chr1:8686608-8686688 47 4.08e-05 aacccctctc tgaccaca gacatgccag chr19:8569207-8569287 50 4.08e-05 GGACAAGCCC TGACCACA GAGCTCAGCC chr6:52166274-52166354 66 4.08e-05 TGAAGATAGT TGACCACA ACActgc chr10:49676378-49676458 56 4.08e-05 gaaggaagtt tgaccaca gtggaggcgg chr7:50626284-50626364 58 4.08e-05 ctgtttaact tgaccaca gccacacagc chr6:107268390-107268470 36 4.08e-05 gcattcctgc tgaccaca aaccccacac chr9:124813831-124813911 18 4.08e-05 ccacagctgc tgaccaca acaaaaccta chr5:52839380-52839460 4 4.08e-05 agc tgaccaca tttttcttgt chr2:232410376-232410456 37 4.08e-05 GGGCTGTATC TGACCACA CAAACCACCA chr13:114035492-11403557 34 4.08e-05 tgacctctgg tgaccaca aacctgacct chr19:8634117-8634197 41 4.08e-05 tggtcacagt tgaccaca agctgaatat chr10:5593769-5593849 31 4.08e-05 CTCCCCTCGT TGACCACA GCCTCCCCTC chr3:131514381-131514461 67 5.66e-05 tcctgataag agaccaca gactat chr10:105264217-10526429 12 5.66e-05 ttggagtgaa agaccaca gaggtaaagt chr3:155546441-155546521 72 5.66e-05 tgagtagata agaccaca g chr2:197324418-197324498 43 5.66e-05 tcttgataag agaccaca gaccacagag chr12:4430057-4430137 17 7.24e-05 TCAATCGCAA CAACCACA AATCAGTGCG chr6:2543230-2543310 51 7.24e-05 aagaaaccac caaccaca gagtggttct chr22:23006443-23006523 49 7.24e-05 GACCAAGGAT CAACCACA CACAGCAGGG chr6:2752292-2752372 16 7.24e-05 GCTGCTGATC CAACCACA TCCTCCACCC chr8:141640633-141640713 56 7.24e-05 GAGGAGAGAG CAACCACA GGCAGCACAG chr2:64582049-64582129 12 7.24e-05 GTCCCACCTT CAACCACA AGCAAACTTC chr7:91763135-91763215 46 7.24e-05 CAGACCGCTA CAACCACA AATGCCGCAA chr2:16931603-16931683 6 8.81e-05 tctgt gaaccaca ccctaatctt chr8:21366960-21367040 70 8.81e-05 ccaaattact gaaccaca gaa chr7:142506649-142506729 72 8.81e-05 AGCATCATGA GAACCACA C chr1:201123014-201123094 7 1.07e-04 AACACC CGACCACA GCCACCAAAG chr1:162342672-162342752 24 1.07e-04 CTGTGGGGAA CGACCACA AATGAGGTTT chr1:246588567-246588647 25 1.07e-04 CATTCAGAAA CGACCACA GCTCTCCTGG chr16:58299539-58299619 72 1.53e-04 gtgtggctct aagccaca a chr3:45615766-45615846 69 1.53e-04 cccattctac aagccaca ctac chr17:56413377-56413457 28 1.53e-04 AACAAGAGAG AAGCCACA GACTTAACCA chr6:28534094-28534174 53 1.53e-04 acccccaccc taaccgca tgtgcggtta chr12:110531903-11053198 16 1.53e-04 TTGCTGTGGG AAGCCACA GAGCAGACAG chr8:74660219-74660299 42 1.53e-04 GTGTCCtggt taaccgca agggcgccag chr1:16478045-16478125 58 1.53e-04 CTCACCACAA AAGCCACA GAGCAGGCAG chr22:39632592-39632672 46 1.69e-04 TCCTCCAGGG AAACCGCA GGTCCCACAA chr3:24561738-24561818 11 1.69e-04 AAGACCTTGG AAACCGCA ACTTGGTTTT chr11:124146166-12414624 33 1.69e-04 TCATGCACAT AAACCGCA GGACCACTGG chr6:34530798-34530878 27 1.69e-04 GGGCCTTACA AAACCGCA GGCCCAGATA chr1:101251434-101251514 68 1.69e-04 agttgtgtta aaaccgca aaaag chr6:13355811-13355891 7 1.88e-04 GTGGTT GGACCACA GCAATGCTAC chr7:135335818-135335898 9 1.88e-04 AATCGTAG GGACCACA TCAAAGGCAG chr2:28578546-28578626 57 2.18e-04 GAGGTTACTG TGGCCACA GCTGCCACTG chr22:19183448-19183528 15 2.18e-04 AACTGAGGCC TGGCCACA AGGGCGTGGT chr4:122911797-122911877 17 2.18e-04 acgcctcaga taaccact aagtccaagg chr22:19006740-19006820 43 2.18e-04 AGTGCCCAGG TAACCACT CCTGGGAGCA chr1:11847431-11847511 33 2.83e-04 TGCTGGACAC AGGCCACA GAGCTGGTGC chr7:765349-765429 18 2.83e-04 atgcagctag aggccaca agattccaaa chr22:23252961-23253041 40 2.83e-04 CTCCAAGACA AGGCCACA CTGGTGTGTC chr15:50552894-50552974 34 2.83e-04 tgacagagag aggccaca tccctgtggt chr16:75109231-75109311 61 2.83e-04 GGAAGCAGCA TGACCGCA GTGGGTTCCT chrX:153946223-153946303 19 2.83e-04 GGATGACGGC TGACCGCA GGGAGATTTA chr7:155102380-155102460 5 2.83e-04 CTCC TCACCACA GGCACCCGGT chr11:46563394-46563474 19 3.37e-04 ACTCCAGATA CAGCCACA ACATCTATAG chr6:28303865-28303945 54 3.56e-04 AATGACCGAT CAACCGCA AAGGCCGGAA chr1:206908993-206909073 8 3.56e-04 ccatctt caaccgca accttgcatt chr17:47438816-47438896 35 3.56e-04 GGTTTGGGTG CAACCGCA AGGCGGGGGA chr6:43753137-43753217 73 3.86e-04 GTTGCCCAGG AGACCACT chr9:111539305-111539385 73 3.86e-04 tcctgataag agaccact chr11:46358479-46358559 36 4.05e-04 aggctgcggt gagccaca attgcgccac chr1:206274320-206274400 57 4.62e-04 aactgaccac caaccact gactggctct chrX:48794395-48794475 32 4.62e-04 GTGGGTTCTG CGGCCACA CTCTCCCCCG chr7:26228401-26228481 61 5.19e-04 AAGAACCCTC CCACCACA TTCTGTGACC chr20:47654647-47654727 71 5.19e-04 GTCCCTCCCT CCACCACA AA chr1:95100667-95100747 31 5.97e-04 GAGAGATCAG AAACCAGA CTGGGAGCGG chr7:101372839-101372919 73 6.48e-04 CCGGAGGGCT GGGCCACA chr22:22454821-22454901 32 6.48e-04 AAGATGGCAG TAACCTCA CTGCTGAGCT chr1:3691505-3691585 26 6.48e-04 AGCCTAGATT GGGCCACA ATGTCCTCGT chr6:90031434-90031514 17 6.48e-04 cagaactgca gaaccact ctgcggtcag chr7:151092670-151092750 45 7.20e-04 cccagcccca ggaccgca aggcctccgt chr1:148604888-148604968 5 7.20e-04 ATTC GCACCACA GAAGCAccag chr22:22053371-22053451 65 7.20e-04 GTGCCTGCCT GGACCGCA GGTCTGGG chr8:142046309-142046389 27 7.20e-04 GCCTGACCGC GGACCGCA GGCAGCACTT chr9:139568717-139568797 26 7.66e-04 TCTCCAACTT TGACCCCA CTGTCCTGCC chr6:13381100-13381180 42 7.66e-04 ACAAAGCATC TGACCCCA GATTGCCCAG chr22:23449902-23449982 14 8.95e-04 CCCAGGGGGT TGGCCGCA GGGTGTGAAA chr11:65194724-65194804 4 8.95e-04 TGG AAGCCACT GCCAGCCTCT chr3:32750982-32751062 16 8.95e-04 GCTCATGTGG TTACCACA GGACAAGTGG chr15:70384458-70384538 44 8.95e-04 TGCTCAGGCC TAACCACC ATTCGCCAAA chr9:101002920-101003000 72 8.95e-04 GGGGTGTGGG AAAGCACA G chr7:127684242-127684322 16 8.95e-04 AAGTGTCCTG TCGCCACA CTTGGGCCAA chr1:12263819-12263899 40 1.01e-03 acttatctgc tcaccgca gcctccgcct chr15:80446410-80446490 46 1.01e-03 CTGGCCGGGC TGACCAGA TGTTGCAAGG chr1:8918312-8918392 34 1.01e-03 TCAATGTGGT AAACCGCT CAGTCCAGCC chr12:94483804-94483884 32 1.01e-03 ttgattgctc aaaccacc atctgcggtt chr5:133268509-133268589 62 1.07e-03 cttatccggg agaccaga tgcagttcct chr13:22562089-22562169 55 1.07e-03 TGCCTGCGGT CAACCCCA GATCCTCCAG chr10:82532454-82532534 68 1.07e-03 cccatcaccc caacccca accaa chr3:47388853-47388933 26 1.12e-03 TCCCCAAATA CAGCCGCA TTCCAGATCT chr22:23378951-23379031 59 1.12e-03 GCTCTTCCAG TGACCTCA TCCACAGGAA chr19:39872629-39872709 44 1.19e-03 CACACGGTGC TGGCCACT GGGGCTGCAG chr15:39432277-39432357 46 1.29e-03 TGCAGTGATA AGAGCACA GCTGTGGGAA chr5:55788787-55788867 55 1.29e-03 tccgtgctgg tcaccact gataatgtct -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif WRACCACA MEME-1 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr2:169952261-169952341 1.3e-05 22_[+1]_50 chr12:122087925-12208800 1.3e-05 58_[+1]_14 chr9:139129834-139129914 1.3e-05 55_[+1]_17 chr22:36864185-36864265 1.3e-05 15_[+1]_57 chr21:43885725-43885805 1.3e-05 52_[+1]_20 chr1:218550823-218550903 1.3e-05 18_[+1]_54 chr19:54714723-54714803 1.3e-05 36_[+1]_36 chr6:71021976-71022056 1.3e-05 17_[+1]_55 chr11:72526278-72526358 1.3e-05 49_[+1]_23 chr14:100288194-10028827 1.3e-05 9_[+1]_63 chr17:4110422-4110502 1.3e-05 33_[+1]_39 chr10:43264390-43264470 2.6e-05 22_[+1]_50 chr5:177844567-177844647 2.6e-05 14_[+1]_58 chr2:30476947-30477027 2.6e-05 60_[+1]_12 chr3:185694888-185694968 2.6e-05 20_[+1]_52 chr15:89545664-89545744 2.6e-05 61_[+1]_11 chr1:220081003-220081083 2.6e-05 56_[+1]_16 chr5:131450384-131450464 2.6e-05 71_[+1]_1 chr10:96059364-96059444 2.6e-05 47_[+1]_25 chr1:207989323-207989403 2.6e-05 72_[+1] chr12:113646077-11364615 2.6e-05 53_[+1]_19 chr16:69899741-69899821 2.6e-05 63_[+1]_9 chr11:18715085-18715165 2.6e-05 37_[+1]_35 chr17:72711397-72711477 2.6e-05 54_[+1]_18 chr3:5796488-5796568 2.6e-05 50_[+1]_22 chr8:42074684-42074764 2.6e-05 47_[+1]_25 chr2:109830637-109830717 2.6e-05 54_[+1]_18 chr5:74677418-74677498 2.6e-05 27_[+1]_45 chr11:63862129-63862209 4.1e-05 50_[+1]_22 chr4:79542717-79542797 4.1e-05 1_[+1]_71 chr1:8686608-8686688 4.1e-05 46_[+1]_26 chr19:8569207-8569287 4.1e-05 49_[+1]_23 chr6:52166274-52166354 4.1e-05 65_[+1]_7 chr10:49676378-49676458 4.1e-05 55_[+1]_17 chr7:50626284-50626364 4.1e-05 57_[+1]_15 chr6:107268390-107268470 4.1e-05 35_[+1]_37 chr9:124813831-124813911 4.1e-05 17_[+1]_55 chr5:52839380-52839460 4.1e-05 3_[+1]_69 chr2:232410376-232410456 4.1e-05 36_[+1]_36 chr13:114035492-11403557 4.1e-05 33_[+1]_39 chr19:8634117-8634197 4.1e-05 40_[+1]_32 chr10:5593769-5593849 4.1e-05 30_[+1]_42 chr3:131514381-131514461 5.7e-05 66_[+1]_6 chr10:105264217-10526429 5.7e-05 11_[+1]_61 chr3:155546441-155546521 5.7e-05 71_[+1]_1 chr2:197324418-197324498 5.7e-05 42_[+1]_30 chr12:4430057-4430137 7.2e-05 16_[+1]_56 chr6:2543230-2543310 7.2e-05 50_[+1]_22 chr22:23006443-23006523 7.2e-05 48_[+1]_24 chr6:2752292-2752372 7.2e-05 15_[+1]_57 chr8:141640633-141640713 7.2e-05 55_[+1]_17 chr2:64582049-64582129 7.2e-05 11_[+1]_61 chr7:91763135-91763215 7.2e-05 45_[+1]_27 chr2:16931603-16931683 8.8e-05 5_[+1]_67 chr8:21366960-21367040 8.8e-05 69_[+1]_3 chr7:142506649-142506729 8.8e-05 71_[+1]_1 chr1:201123014-201123094 0.00011 6_[+1]_66 chr1:162342672-162342752 0.00011 23_[+1]_49 chr1:246588567-246588647 0.00011 24_[+1]_48 chr16:58299539-58299619 0.00015 71_[+1]_1 chr3:45615766-45615846 0.00015 68_[+1]_4 chr17:56413377-56413457 0.00015 27_[+1]_45 chr6:28534094-28534174 0.00015 52_[+1]_20 chr12:110531903-11053198 0.00015 15_[+1]_57 chr8:74660219-74660299 0.00015 41_[+1]_31 chr1:16478045-16478125 0.00015 57_[+1]_15 chr22:39632592-39632672 0.00017 45_[+1]_27 chr3:24561738-24561818 0.00017 10_[+1]_62 chr11:124146166-12414624 0.00017 32_[+1]_40 chr6:34530798-34530878 0.00017 26_[+1]_46 chr1:101251434-101251514 0.00017 67_[+1]_5 chr6:13355811-13355891 0.00019 6_[+1]_66 chr7:135335818-135335898 0.00019 8_[+1]_64 chr2:28578546-28578626 0.00022 56_[+1]_16 chr22:19183448-19183528 0.00022 14_[+1]_58 chr4:122911797-122911877 0.00022 16_[+1]_56 chr22:19006740-19006820 0.00022 42_[+1]_30 chr1:11847431-11847511 0.00028 32_[+1]_40 chr7:765349-765429 0.00028 17_[+1]_55 chr22:23252961-23253041 0.00028 39_[+1]_33 chr15:50552894-50552974 0.00028 33_[+1]_39 chr16:75109231-75109311 0.00028 60_[+1]_12 chrX:153946223-153946303 0.00028 18_[+1]_54 chr7:155102380-155102460 0.00028 4_[+1]_68 chr11:46563394-46563474 0.00034 18_[+1]_54 chr6:28303865-28303945 0.00036 53_[+1]_19 chr1:206908993-206909073 0.00036 7_[+1]_65 chr17:47438816-47438896 0.00036 34_[+1]_38 chr6:43753137-43753217 0.00039 72_[+1] chr9:111539305-111539385 0.00039 72_[+1] chr11:46358479-46358559 0.0004 35_[+1]_37 chr1:206274320-206274400 0.00046 56_[+1]_16 chrX:48794395-48794475 0.00046 31_[+1]_41 chr7:26228401-26228481 0.00052 60_[+1]_12 chr20:47654647-47654727 0.00052 70_[+1]_2 chr1:95100667-95100747 0.0006 30_[+1]_42 chr7:101372839-101372919 0.00065 72_[+1] chr22:22454821-22454901 0.00065 31_[+1]_41 chr1:3691505-3691585 0.00065 25_[+1]_47 chr6:90031434-90031514 0.00065 16_[+1]_56 chr7:151092670-151092750 0.00072 44_[+1]_28 chr1:148604888-148604968 0.00072 4_[+1]_68 chr22:22053371-22053451 0.00072 64_[+1]_8 chr8:142046309-142046389 0.00072 26_[+1]_46 chr9:139568717-139568797 0.00077 25_[+1]_47 chr6:13381100-13381180 0.00077 41_[+1]_31 chr22:23449902-23449982 0.00089 13_[+1]_59 chr11:65194724-65194804 0.00089 3_[+1]_69 chr3:32750982-32751062 0.00089 15_[+1]_57 chr15:70384458-70384538 0.00089 43_[+1]_29 chr9:101002920-101003000 0.00089 71_[+1]_1 chr7:127684242-127684322 0.00089 15_[+1]_57 chr1:12263819-12263899 0.001 39_[+1]_33 chr15:80446410-80446490 0.001 45_[+1]_27 chr1:8918312-8918392 0.001 33_[+1]_39 chr12:94483804-94483884 0.001 31_[+1]_41 chr5:133268509-133268589 0.0011 61_[+1]_11 chr13:22562089-22562169 0.0011 54_[+1]_18 chr10:82532454-82532534 0.0011 67_[+1]_5 chr3:47388853-47388933 0.0011 25_[+1]_47 chr22:23378951-23379031 0.0011 58_[+1]_14 chr19:39872629-39872709 0.0012 43_[+1]_29 chr15:39432277-39432357 0.0013 45_[+1]_27 chr5:55788787-55788867 0.0013 54_[+1]_18 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif WRACCACA MEME-1 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF WRACCACA width=8 seqs=124 chr2:169952261-169952341 ( 23) TAACCACA 1 chr12:122087925-12208800 ( 59) TAACCACA 1 chr9:139129834-139129914 ( 56) TAACCACA 1 chr22:36864185-36864265 ( 16) TAACCACA 1 chr21:43885725-43885805 ( 53) TAACCACA 1 chr1:218550823-218550903 ( 19) TAACCACA 1 chr19:54714723-54714803 ( 37) TAACCACA 1 chr6:71021976-71022056 ( 18) TAACCACA 1 chr11:72526278-72526358 ( 50) TAACCACA 1 chr14:100288194-10028827 ( 10) TAACCACA 1 chr17:4110422-4110502 ( 34) TAACCACA 1 chr10:43264390-43264470 ( 23) AAACCACA 1 chr5:177844567-177844647 ( 15) AAACCACA 1 chr2:30476947-30477027 ( 61) AAACCACA 1 chr3:185694888-185694968 ( 21) AAACCACA 1 chr15:89545664-89545744 ( 62) AAACCACA 1 chr1:220081003-220081083 ( 57) AAACCACA 1 chr5:131450384-131450464 ( 72) AAACCACA 1 chr10:96059364-96059444 ( 48) AAACCACA 1 chr1:207989323-207989403 ( 73) AAACCACA 1 chr12:113646077-11364615 ( 54) AAACCACA 1 chr16:69899741-69899821 ( 64) AAACCACA 1 chr11:18715085-18715165 ( 38) AAACCACA 1 chr17:72711397-72711477 ( 55) AAACCACA 1 chr3:5796488-5796568 ( 51) AAACCACA 1 chr8:42074684-42074764 ( 48) AAACCACA 1 chr2:109830637-109830717 ( 55) AAACCACA 1 chr5:74677418-74677498 ( 28) AAACCACA 1 chr11:63862129-63862209 ( 51) TGACCACA 1 chr4:79542717-79542797 ( 2) TGACCACA 1 chr1:8686608-8686688 ( 47) TGACCACA 1 chr19:8569207-8569287 ( 50) TGACCACA 1 chr6:52166274-52166354 ( 66) TGACCACA 1 chr10:49676378-49676458 ( 56) TGACCACA 1 chr7:50626284-50626364 ( 58) TGACCACA 1 chr6:107268390-107268470 ( 36) TGACCACA 1 chr9:124813831-124813911 ( 18) TGACCACA 1 chr5:52839380-52839460 ( 4) TGACCACA 1 chr2:232410376-232410456 ( 37) TGACCACA 1 chr13:114035492-11403557 ( 34) TGACCACA 1 chr19:8634117-8634197 ( 41) TGACCACA 1 chr10:5593769-5593849 ( 31) TGACCACA 1 chr3:131514381-131514461 ( 67) AGACCACA 1 chr10:105264217-10526429 ( 12) AGACCACA 1 chr3:155546441-155546521 ( 72) AGACCACA 1 chr2:197324418-197324498 ( 43) AGACCACA 1 chr12:4430057-4430137 ( 17) CAACCACA 1 chr6:2543230-2543310 ( 51) CAACCACA 1 chr22:23006443-23006523 ( 49) CAACCACA 1 chr6:2752292-2752372 ( 16) CAACCACA 1 chr8:141640633-141640713 ( 56) CAACCACA 1 chr2:64582049-64582129 ( 12) CAACCACA 1 chr7:91763135-91763215 ( 46) CAACCACA 1 chr2:16931603-16931683 ( 6) GAACCACA 1 chr8:21366960-21367040 ( 70) GAACCACA 1 chr7:142506649-142506729 ( 72) GAACCACA 1 chr1:201123014-201123094 ( 7) CGACCACA 1 chr1:162342672-162342752 ( 24) CGACCACA 1 chr1:246588567-246588647 ( 25) CGACCACA 1 chr16:58299539-58299619 ( 72) AAGCCACA 1 chr3:45615766-45615846 ( 69) AAGCCACA 1 chr17:56413377-56413457 ( 28) AAGCCACA 1 chr6:28534094-28534174 ( 53) TAACCGCA 1 chr12:110531903-11053198 ( 16) AAGCCACA 1 chr8:74660219-74660299 ( 42) TAACCGCA 1 chr1:16478045-16478125 ( 58) AAGCCACA 1 chr22:39632592-39632672 ( 46) AAACCGCA 1 chr3:24561738-24561818 ( 11) AAACCGCA 1 chr11:124146166-12414624 ( 33) AAACCGCA 1 chr6:34530798-34530878 ( 27) AAACCGCA 1 chr1:101251434-101251514 ( 68) AAACCGCA 1 chr6:13355811-13355891 ( 7) GGACCACA 1 chr7:135335818-135335898 ( 9) GGACCACA 1 chr2:28578546-28578626 ( 57) TGGCCACA 1 chr22:19183448-19183528 ( 15) TGGCCACA 1 chr4:122911797-122911877 ( 17) TAACCACT 1 chr22:19006740-19006820 ( 43) TAACCACT 1 chr1:11847431-11847511 ( 33) AGGCCACA 1 chr7:765349-765429 ( 18) AGGCCACA 1 chr22:23252961-23253041 ( 40) AGGCCACA 1 chr15:50552894-50552974 ( 34) AGGCCACA 1 chr16:75109231-75109311 ( 61) TGACCGCA 1 chrX:153946223-153946303 ( 19) TGACCGCA 1 chr7:155102380-155102460 ( 5) TCACCACA 1 chr11:46563394-46563474 ( 19) CAGCCACA 1 chr6:28303865-28303945 ( 54) CAACCGCA 1 chr1:206908993-206909073 ( 8) CAACCGCA 1 chr17:47438816-47438896 ( 35) CAACCGCA 1 chr6:43753137-43753217 ( 73) AGACCACT 1 chr9:111539305-111539385 ( 73) AGACCACT 1 chr11:46358479-46358559 ( 36) GAGCCACA 1 chr1:206274320-206274400 ( 57) CAACCACT 1 chrX:48794395-48794475 ( 32) CGGCCACA 1 chr7:26228401-26228481 ( 61) CCACCACA 1 chr20:47654647-47654727 ( 71) CCACCACA 1 chr1:95100667-95100747 ( 31) AAACCAGA 1 chr7:101372839-101372919 ( 73) GGGCCACA 1 chr22:22454821-22454901 ( 32) TAACCTCA 1 chr1:3691505-3691585 ( 26) GGGCCACA 1 chr6:90031434-90031514 ( 17) GAACCACT 1 chr7:151092670-151092750 ( 45) GGACCGCA 1 chr1:148604888-148604968 ( 5) GCACCACA 1 chr22:22053371-22053451 ( 65) GGACCGCA 1 chr8:142046309-142046389 ( 27) GGACCGCA 1 chr9:139568717-139568797 ( 26) TGACCCCA 1 chr6:13381100-13381180 ( 42) TGACCCCA 1 chr22:23449902-23449982 ( 14) TGGCCGCA 1 chr11:65194724-65194804 ( 4) AAGCCACT 1 chr3:32750982-32751062 ( 16) TTACCACA 1 chr15:70384458-70384538 ( 44) TAACCACC 1 chr9:101002920-101003000 ( 72) AAAGCACA 1 chr7:127684242-127684322 ( 16) TCGCCACA 1 chr1:12263819-12263899 ( 40) TCACCGCA 1 chr15:80446410-80446490 ( 46) TGACCAGA 1 chr1:8918312-8918392 ( 34) AAACCGCT 1 chr12:94483804-94483884 ( 32) AAACCACC 1 chr5:133268509-133268589 ( 62) AGACCAGA 1 chr13:22562089-22562169 ( 55) CAACCCCA 1 chr10:82532454-82532534 ( 68) CAACCCCA 1 chr3:47388853-47388933 ( 26) CAGCCGCA 1 chr22:23378951-23379031 ( 59) TGACCTCA 1 chr19:39872629-39872709 ( 44) TGGCCACT 1 chr15:39432277-39432357 ( 46) AGAGCACA 1 chr5:55788787-55788867 ( 55) TCACCACT 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif WRACCACA MEME-1 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 7.90166 E= 1.4e-062 63 -70 -140 76 128 -228 46 -476 186 -1360 -70 -1360 -1360 184 -409 -1360 -1360 186 -1360 -1360 180 -309 -85 -377 -1360 183 -351 -1360 198 -409 -1360 -145 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif WRACCACA MEME-1 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 124 E= 1.4e-062 0.354839 0.169355 0.104839 0.370968 0.556452 0.056452 0.379032 0.008065 0.830645 0.000000 0.169355 0.000000 0.000000 0.983871 0.016129 0.000000 0.000000 1.000000 0.000000 0.000000 0.798387 0.032258 0.153226 0.016129 0.000000 0.975806 0.024194 0.000000 0.903226 0.016129 0.000000 0.080645 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif WRACCACA MEME-1 regular expression -------------------------------------------------------------------------------- [TA][AG]ACCACA -------------------------------------------------------------------------------- Time 4.93 secs. ******************************************************************************** ******************************************************************************** MOTIF YTGTGGTY MEME-2 width = 8 sites = 82 llr = 687 E-value = 5.8e-059 ******************************************************************************** -------------------------------------------------------------------------------- Motif YTGTGGTY MEME-2 Description -------------------------------------------------------------------------------- Simplified A :::::::: pos.-specific C 6::2::13 probability G ::a:aa:1 matrix T 3a:8::96 bits 2.2 2.0 * 1.7 ** ** 1.5 ** *** Relative 1.3 ****** Entropy 1.1 ****** (12.1 bits) 0.9 ******** 0.7 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel CTGTGGTT consensus T C C sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YTGTGGTY MEME-2 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr16:66558871-66558951 25 1.35e-05 CCTTCCCCTC CTGTGGTT AGTTCCTGCC chr6:43804457-43804537 57 1.35e-05 AAAGGGTCAG CTGTGGTT ATGACTGGCT chr6:36922157-36922237 5 1.35e-05 GGGT CTGTGGTT TCCTTTCTCT chr2:152991634-152991714 32 1.35e-05 CGCTTTGCCT CTGTGGTT CACTGATGAA chr3:32750982-32751062 51 1.35e-05 TGATAGCGCT CTGTGGTT CTTTGGGAAG chr3:47388853-47388933 61 1.35e-05 CAAGATTACA CTGTGGTT AGTGTGGTTT chr1:24648870-24648950 33 1.35e-05 CGCCTCCCCG CTGTGGTT TTGTGGTCGA chr5:66502916-66502996 3 1.35e-05 GG CTGTGGTT TTTCAGAGAA chrX:153946223-153946303 42 1.35e-05 ATTTATAGCT CTGTGGTT TTTCTCTCCC chr3:126627725-126627805 27 1.35e-05 tgacccttgc ctgtggtt acacacccgg chr4:6927285-6927365 28 1.35e-05 GTGGTGTGGT CTGTGGTT TTGTCGGGAA chr1:101251434-101251514 19 1.35e-05 cagaaccatt ctgtggtt ggcggtctct chr5:55788787-55788867 32 1.35e-05 GTGGTCCAcc ctgtggtt ttccatccgt chr11:72526278-72526358 35 1.35e-05 GATTGTATGT CTGTGGTT GGAAGTCTAA chr9:126817218-126817298 44 1.35e-05 CCCTTCTTTG CTGTGGTT TCCTTGTAGG chr14:100288194-10028827 39 1.35e-05 GGGAATGTAT CTGTGGTT AGATAGCTAG chr11:120215191-12021527 37 1.35e-05 AGTACAGTCT CTGTGGTT TACTGAGAGG chr18:11925946-11926026 33 2.44e-05 ggtgtttatc ttgtggtt ggaatgtttc chr3:131514381-131514461 22 2.44e-05 cccctccctt ttgtggtt ttaacaaaac chr2:159986996-159987076 32 2.44e-05 ATTAGTGTCA TTGTGGTT TAATAGGTGG chr6:2543230-2543310 7 2.44e-05 tccctt ttgtggtt tcaacacaac chr20:30263251-30263331 69 2.44e-05 GAAGTGAGGT TTGTGGTT GGAA chr15:80446410-80446490 22 2.44e-05 AAGAGTCAAC TTGTGGTT TCACATCTGG chr3:167659496-167659576 39 2.44e-05 TCCAGCTTCT TTGTGGTT TCCCCCGCCC chr12:90127536-90127616 12 2.44e-05 CACGAGAGCC TTGTGGTT tggtggataa chr2:121049509-121049589 4 2.44e-05 AGC TTGTGGTT TTGTGTGAAT chr5:52839380-52839460 18 2.44e-05 cacatttttc ttgtggtt ttgcatgccT chr6:2974088-2974168 21 2.44e-05 acccgataac ttgtggtt gtgggggctg chr9:111539305-111539385 28 2.44e-05 ctcgccattt ttgtggtt ttggcacagc chr7:127684242-127684322 40 2.44e-05 CCAATGGCAC TTGTGGTT TGTGTGTTAT chr1:206908993-206909073 38 4.13e-05 tctgatcctt ctgtggtc acttctctga chr15:50552894-50552974 45 4.13e-05 ggccacatcc ctgtggtc acacaTACCC chr3:141765327-141765407 7 4.13e-05 ACAGAG CTGTGGTC ACTAAGGGAA chr4:140187965-140188045 60 4.13e-05 GCACTGACTG CTGTGGTC TCCGGAGCAG chr5:55457907-55457987 33 4.13e-05 AGGAGGTCAG CTGTGGTC CAGTGTGGTT chr5:95220395-95220475 30 4.13e-05 aacacagatg ctgtggtc agacttccca chr11:113953644-11395372 6 4.13e-05 CTCGG CTGTGGTC GTAGCACTAC chr11:70270384-70270464 32 4.13e-05 TTGTGGGTGT CTGTGGTC AGCATTGCTG chr1:165362392-165362472 42 4.13e-05 GCCAGTTCCt ctgtggtc tgtggtctgt chr7:104771655-104771735 15 5.49e-05 CTAGTGGCCA TTGTGGTC TAACCTCCCC chr1:207989323-207989403 62 5.49e-05 CAGTCAGCAC TTGTGGTC ACAAAACCAC chr19:33162868-33162948 24 5.49e-05 ACTCGTGGTT TTGTGGTC TTCAACCGTC chr19:8634117-8634197 28 5.49e-05 AACGaagagc ttgtggtc acagttgacc chr6:170404951-170405031 35 5.49e-05 GGCCTGAGCT TTGTGGTC TGGCGGGGCC chr2:15870767-15870847 51 7.18e-05 ATGCCGGCTG CTGCGGTT TGGCAGTGGG chr6:17600487-17600567 54 7.18e-05 TTGTTGACGC CTGCGGTT GCTGCGGTGG chr12:94483804-94483884 42 7.18e-05 aaaccaccat ctgcggtt tctcttgtta chr2:20624732-20624812 22 7.18e-05 AGCAGGAGGC CTGCGGTT GGAGGGCATT chr3:13049195-13049275 60 7.18e-05 CTGCCTATCT CTGCGGTT TCTGTGCTTG chr3:130506665-130506745 54 7.18e-05 CGGTTTGCAG CTGCGGTT TGCAACCTTG chr22:36876218-36876298 40 8.53e-05 CCAGCCCTTC TTGCGGTT TTCATGGCAG chr1:172715569-172715649 39 8.53e-05 TGATGTGGTT TTGCGGTT ATACAGTAAG chr3:45615766-45615846 23 8.53e-05 actgaaacaa ttgcggtt catcccacag chr17:60996882-60996962 38 1.02e-04 GTCATGGTTT CTGTGGCT GCCCAGCTGT chr2:232410376-232410456 19 1.02e-04 TTGCCTCTTC CTGTGGCT GGGCTGTATC chr7:101372839-101372919 9 1.23e-04 ACCAAAGG CTGCGGTC GCCGTGCATG chr3:133472785-133472865 44 1.23e-04 CTGAAGGCTA CTGCGGTC TACTGATATG chr15:82237467-82237547 23 1.23e-04 tcctcctccc ctgcggtc tcacgatctg chr3:133175004-133175084 40 1.23e-04 TTTGAGGCAT CTGCGGTC AGGAACTTTA chr3:155546441-155546521 13 1.23e-04 taatggctca ctgcggtc tctggctcct chr7:91763135-91763215 24 1.23e-04 GGCACCACTG CTGCGGTC AGTACAGACC chr6:90031434-90031514 25 1.23e-04 cagaaccact ctgcggtc agtggtcact chr15:70740421-70740501 20 1.40e-04 AGCGAGCGCG CTGTGGTG AGCGCGATAA chr1:12043659-12043739 13 1.40e-04 GTGGCAAGGT CTGTGGTG AAGCAGAGAT chr1:247711569-247711649 55 1.54e-04 AGCTTGTGCT TTGTGGCT CTGGTGGGCA chr1:234866552-234866632 41 1.54e-04 GGCCAGGGAG TTGTGGCT TCTGAGATAA chr6:16224773-16224853 53 1.54e-04 ttcctcattt ttgtggct tgctgggcca chr19:8569207-8569287 13 1.84e-04 AGGCAGTCAC TTGTGGTG CCGAGGACTG chr11:33906983-33907063 5 1.84e-04 GGTT TTGTGGTG CAAATAAGGG chr22:20810690-20810770 31 2.31e-04 GGCTGCCCCT CTGTGGCC AAGCTGGAGA chr2:30476947-30477027 48 2.31e-04 ccaggacaca cagtggtt gcctgaaacc chr20:3890858-3890938 2 2.31e-04 G CTGTGGCC TGAGCTTGGT chr22:22313504-22313584 53 2.31e-04 AGGGGCTTGC CTGTGGCC GCCAGGGGCG chr22:36864185-36864265 41 2.31e-04 CTCACTGGCC CAGTGGTT TTGCTGGAAT chr2:109830637-109830717 39 2.31e-04 agctgtcagc atgtggtt tatgggtaaa chr7:142502496-142502576 19 2.59e-04 TATTGGAGGA TAGTGGTT TGTGTGGGCA chr12:110531903-11053198 69 2.59e-04 TTGTCTTATC TTGTGGCC CCCT chr10:127293925-12729400 28 3.12e-04 TAGTGCAGCA ATGTGGTC AGTTAATCTC chr3:5796488-5796568 29 3.12e-04 ctcaaagtgt cagtggtc agaggcccag chr12:113646077-11364615 33 3.47e-04 GCTGACATCT GTGTGGTT AGTGTGGCTG chr2:54798219-54798299 28 3.47e-04 TGTGGGAAGT CTGCGGTG AAGAGTGGTG chr22:21804773-21804853 19 4.53e-04 CCCTGCCCTC CTGCGGCC ATCCTGAGTT -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YTGTGGTY MEME-2 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr16:66558871-66558951 1.4e-05 24_[+2]_48 chr6:43804457-43804537 1.4e-05 56_[+2]_16 chr6:36922157-36922237 1.4e-05 4_[+2]_68 chr2:152991634-152991714 1.4e-05 31_[+2]_41 chr3:32750982-32751062 1.4e-05 50_[+2]_22 chr3:47388853-47388933 1.4e-05 60_[+2]_12 chr1:24648870-24648950 1.4e-05 32_[+2]_40 chr5:66502916-66502996 1.4e-05 2_[+2]_70 chrX:153946223-153946303 1.4e-05 41_[+2]_31 chr3:126627725-126627805 1.4e-05 26_[+2]_46 chr4:6927285-6927365 1.4e-05 27_[+2]_45 chr1:101251434-101251514 1.4e-05 18_[+2]_54 chr5:55788787-55788867 1.4e-05 31_[+2]_41 chr11:72526278-72526358 1.4e-05 34_[+2]_38 chr9:126817218-126817298 1.4e-05 43_[+2]_29 chr14:100288194-10028827 1.4e-05 38_[+2]_34 chr11:120215191-12021527 1.4e-05 36_[+2]_36 chr18:11925946-11926026 2.4e-05 32_[+2]_40 chr3:131514381-131514461 2.4e-05 21_[+2]_51 chr2:159986996-159987076 2.4e-05 31_[+2]_41 chr6:2543230-2543310 2.4e-05 6_[+2]_66 chr20:30263251-30263331 2.4e-05 68_[+2]_4 chr15:80446410-80446490 2.4e-05 21_[+2]_51 chr3:167659496-167659576 2.4e-05 38_[+2]_34 chr12:90127536-90127616 2.4e-05 11_[+2]_61 chr2:121049509-121049589 2.4e-05 3_[+2]_69 chr5:52839380-52839460 2.4e-05 17_[+2]_55 chr6:2974088-2974168 2.4e-05 20_[+2]_52 chr9:111539305-111539385 2.4e-05 27_[+2]_45 chr7:127684242-127684322 2.4e-05 39_[+2]_33 chr1:206908993-206909073 4.1e-05 37_[+2]_35 chr15:50552894-50552974 4.1e-05 44_[+2]_28 chr3:141765327-141765407 4.1e-05 6_[+2]_66 chr4:140187965-140188045 4.1e-05 59_[+2]_13 chr5:55457907-55457987 4.1e-05 32_[+2]_40 chr5:95220395-95220475 4.1e-05 29_[+2]_43 chr11:113953644-11395372 4.1e-05 5_[+2]_67 chr11:70270384-70270464 4.1e-05 31_[+2]_41 chr1:165362392-165362472 4.1e-05 41_[+2]_31 chr7:104771655-104771735 5.5e-05 14_[+2]_58 chr1:207989323-207989403 5.5e-05 61_[+2]_11 chr19:33162868-33162948 5.5e-05 23_[+2]_49 chr19:8634117-8634197 5.5e-05 27_[+2]_45 chr6:170404951-170405031 5.5e-05 34_[+2]_38 chr2:15870767-15870847 7.2e-05 50_[+2]_22 chr6:17600487-17600567 7.2e-05 53_[+2]_19 chr12:94483804-94483884 7.2e-05 41_[+2]_31 chr2:20624732-20624812 7.2e-05 21_[+2]_51 chr3:13049195-13049275 7.2e-05 59_[+2]_13 chr3:130506665-130506745 7.2e-05 53_[+2]_19 chr22:36876218-36876298 8.5e-05 39_[+2]_33 chr1:172715569-172715649 8.5e-05 38_[+2]_34 chr3:45615766-45615846 8.5e-05 22_[+2]_50 chr17:60996882-60996962 0.0001 37_[+2]_35 chr2:232410376-232410456 0.0001 18_[+2]_54 chr7:101372839-101372919 0.00012 8_[+2]_64 chr3:133472785-133472865 0.00012 43_[+2]_29 chr15:82237467-82237547 0.00012 22_[+2]_50 chr3:133175004-133175084 0.00012 39_[+2]_33 chr3:155546441-155546521 0.00012 12_[+2]_60 chr7:91763135-91763215 0.00012 23_[+2]_49 chr6:90031434-90031514 0.00012 24_[+2]_48 chr15:70740421-70740501 0.00014 19_[+2]_53 chr1:12043659-12043739 0.00014 12_[+2]_60 chr1:247711569-247711649 0.00015 54_[+2]_18 chr1:234866552-234866632 0.00015 40_[+2]_32 chr6:16224773-16224853 0.00015 52_[+2]_20 chr19:8569207-8569287 0.00018 12_[+2]_60 chr11:33906983-33907063 0.00018 4_[+2]_68 chr22:20810690-20810770 0.00023 30_[+2]_42 chr2:30476947-30477027 0.00023 47_[+2]_25 chr20:3890858-3890938 0.00023 1_[+2]_71 chr22:22313504-22313584 0.00023 52_[+2]_20 chr22:36864185-36864265 0.00023 40_[+2]_32 chr2:109830637-109830717 0.00023 38_[+2]_34 chr7:142502496-142502576 0.00026 18_[+2]_54 chr12:110531903-11053198 0.00026 68_[+2]_4 chr10:127293925-12729400 0.00031 27_[+2]_45 chr3:5796488-5796568 0.00031 28_[+2]_44 chr12:113646077-11364615 0.00035 32_[+2]_40 chr2:54798219-54798299 0.00035 27_[+2]_45 chr22:21804773-21804853 0.00045 18_[+2]_54 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YTGTGGTY MEME-2 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF YTGTGGTY width=8 seqs=82 chr16:66558871-66558951 ( 25) CTGTGGTT 1 chr6:43804457-43804537 ( 57) CTGTGGTT 1 chr6:36922157-36922237 ( 5) CTGTGGTT 1 chr2:152991634-152991714 ( 32) CTGTGGTT 1 chr3:32750982-32751062 ( 51) CTGTGGTT 1 chr3:47388853-47388933 ( 61) CTGTGGTT 1 chr1:24648870-24648950 ( 33) CTGTGGTT 1 chr5:66502916-66502996 ( 3) CTGTGGTT 1 chrX:153946223-153946303 ( 42) CTGTGGTT 1 chr3:126627725-126627805 ( 27) CTGTGGTT 1 chr4:6927285-6927365 ( 28) CTGTGGTT 1 chr1:101251434-101251514 ( 19) CTGTGGTT 1 chr5:55788787-55788867 ( 32) CTGTGGTT 1 chr11:72526278-72526358 ( 35) CTGTGGTT 1 chr9:126817218-126817298 ( 44) CTGTGGTT 1 chr14:100288194-10028827 ( 39) CTGTGGTT 1 chr11:120215191-12021527 ( 37) CTGTGGTT 1 chr18:11925946-11926026 ( 33) TTGTGGTT 1 chr3:131514381-131514461 ( 22) TTGTGGTT 1 chr2:159986996-159987076 ( 32) TTGTGGTT 1 chr6:2543230-2543310 ( 7) TTGTGGTT 1 chr20:30263251-30263331 ( 69) TTGTGGTT 1 chr15:80446410-80446490 ( 22) TTGTGGTT 1 chr3:167659496-167659576 ( 39) TTGTGGTT 1 chr12:90127536-90127616 ( 12) TTGTGGTT 1 chr2:121049509-121049589 ( 4) TTGTGGTT 1 chr5:52839380-52839460 ( 18) TTGTGGTT 1 chr6:2974088-2974168 ( 21) TTGTGGTT 1 chr9:111539305-111539385 ( 28) TTGTGGTT 1 chr7:127684242-127684322 ( 40) TTGTGGTT 1 chr1:206908993-206909073 ( 38) CTGTGGTC 1 chr15:50552894-50552974 ( 45) CTGTGGTC 1 chr3:141765327-141765407 ( 7) CTGTGGTC 1 chr4:140187965-140188045 ( 60) CTGTGGTC 1 chr5:55457907-55457987 ( 33) CTGTGGTC 1 chr5:95220395-95220475 ( 30) CTGTGGTC 1 chr11:113953644-11395372 ( 6) CTGTGGTC 1 chr11:70270384-70270464 ( 32) CTGTGGTC 1 chr1:165362392-165362472 ( 42) CTGTGGTC 1 chr7:104771655-104771735 ( 15) TTGTGGTC 1 chr1:207989323-207989403 ( 62) TTGTGGTC 1 chr19:33162868-33162948 ( 24) TTGTGGTC 1 chr19:8634117-8634197 ( 28) TTGTGGTC 1 chr6:170404951-170405031 ( 35) TTGTGGTC 1 chr2:15870767-15870847 ( 51) CTGCGGTT 1 chr6:17600487-17600567 ( 54) CTGCGGTT 1 chr12:94483804-94483884 ( 42) CTGCGGTT 1 chr2:20624732-20624812 ( 22) CTGCGGTT 1 chr3:13049195-13049275 ( 60) CTGCGGTT 1 chr3:130506665-130506745 ( 54) CTGCGGTT 1 chr22:36876218-36876298 ( 40) TTGCGGTT 1 chr1:172715569-172715649 ( 39) TTGCGGTT 1 chr3:45615766-45615846 ( 23) TTGCGGTT 1 chr17:60996882-60996962 ( 38) CTGTGGCT 1 chr2:232410376-232410456 ( 19) CTGTGGCT 1 chr7:101372839-101372919 ( 9) CTGCGGTC 1 chr3:133472785-133472865 ( 44) CTGCGGTC 1 chr15:82237467-82237547 ( 23) CTGCGGTC 1 chr3:133175004-133175084 ( 40) CTGCGGTC 1 chr3:155546441-155546521 ( 13) CTGCGGTC 1 chr7:91763135-91763215 ( 24) CTGCGGTC 1 chr6:90031434-90031514 ( 25) CTGCGGTC 1 chr15:70740421-70740501 ( 20) CTGTGGTG 1 chr1:12043659-12043739 ( 13) CTGTGGTG 1 chr1:247711569-247711649 ( 55) TTGTGGCT 1 chr1:234866552-234866632 ( 41) TTGTGGCT 1 chr6:16224773-16224853 ( 53) TTGTGGCT 1 chr19:8569207-8569287 ( 13) TTGTGGTG 1 chr11:33906983-33907063 ( 5) TTGTGGTG 1 chr22:20810690-20810770 ( 31) CTGTGGCC 1 chr2:30476947-30477027 ( 48) CAGTGGTT 1 chr20:3890858-3890938 ( 2) CTGTGGCC 1 chr22:22313504-22313584 ( 53) CTGTGGCC 1 chr22:36864185-36864265 ( 41) CAGTGGTT 1 chr2:109830637-109830717 ( 39) ATGTGGTT 1 chr7:142502496-142502576 ( 19) TAGTGGTT 1 chr12:110531903-11053198 ( 69) TTGTGGCC 1 chr10:127293925-12729400 ( 28) ATGTGGTC 1 chr3:5796488-5796568 ( 29) CAGTGGTC 1 chr12:113646077-11364615 ( 33) GTGTGGTT 1 chr2:54798219-54798299 ( 28) CTGCGGTG 1 chr22:21804773-21804853 ( 19) CTGCGGCC 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YTGTGGTY MEME-2 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 9.64284 E= 5.8e-059 -323 118 -450 64 -223 -1300 -1300 211 -1300 -1300 186 -1300 -1300 -33 -1300 183 -1300 -1300 186 -1300 -1300 -1300 186 -1300 -1300 -117 -1300 200 -1300 31 -218 144 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YTGTGGTY MEME-2 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 82 E= 5.8e-059 0.024390 0.621951 0.012195 0.341463 0.048780 0.000000 0.000000 0.951220 0.000000 0.000000 1.000000 0.000000 0.000000 0.219512 0.000000 0.780488 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.121951 0.000000 0.878049 0.000000 0.341463 0.060976 0.597561 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YTGTGGTY MEME-2 regular expression -------------------------------------------------------------------------------- [CT]TG[TC]GGT[TC] -------------------------------------------------------------------------------- Time 8.51 secs. ******************************************************************************** ******************************************************************************** MOTIF CWGATAAG MEME-3 width = 8 sites = 49 llr = 405 E-value = 7.8e-015 ******************************************************************************** -------------------------------------------------------------------------------- Motif CWGATAAG MEME-3 Description -------------------------------------------------------------------------------- Simplified A 26:a:a92 pos.-specific C 5::::::1 probability G 2:a:1:18 matrix T 14::9::: bits 2.2 * * 2.0 * * 1.7 ***** 1.5 ***** Relative 1.3 ***** Entropy 1.1 ****** (11.9 bits) 0.9 ******* 0.7 ******* 0.4 ******* 0.2 ******** 0.0 -------- Multilevel CAGATAAG consensus GT sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CWGATAAG MEME-3 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr19:8569207-8569287 33 1.27e-05 GAGGACTGGC CAGATAAG GACAAGCCCT chr5:10708849-10708929 34 1.27e-05 TTGGGGTCAA CAGATAAG GCTCTGGATG chr19:39872629-39872709 65 1.27e-05 GCTGCAGAGA CAGATAAG GCTCGTCT chr19:33162868-33162948 51 1.27e-05 CCTGCTAGCC CAGATAAG TCTGGGTGGT chr6:34530798-34530878 39 1.27e-05 ACCGCAGGCC CAGATAAG AGCACAATCG chr17:36572790-36572870 54 1.27e-05 gtctggttta cagataag ggagctgcag chr17:60996882-60996962 21 2.48e-05 TGCTCCTGTC CTGATAAG TCATGGTTTC chr3:131514381-131514461 59 2.48e-05 gcatttcttc ctgataag agaccacaga chr6:2543230-2543310 36 2.48e-05 gcgttccttc ctgataag aaaccaccaa chr1:162342672-162342752 52 2.48e-05 TAGCAGCACA CTGATAAG CAGAGCAGCT chrX:107801625-107801705 27 2.48e-05 TGTAAAGGTG CTGATAAG ATATGATGGG chr6:25974324-25974404 38 2.48e-05 tgcttagggt ctgataag gctgcagtta chr17:72711397-72711477 67 2.48e-05 ACCACAGCAG CTGATAAG CCATGG chr9:101002920-101003000 43 2.48e-05 TGTCCTGGGT CTGATAAG CAGTCACCCC chr9:111539305-111539385 65 2.48e-05 gcattccttc ctgataag agaccact chr14:100609049-10060912 28 3.76e-05 CTGGGCTGGG GAGATAAG GAGTTAACAA chr1:234866552-234866632 52 3.76e-05 TGTGGCTTCT GAGATAAG GACTTTGTGC chr10:43911139-43911219 59 3.76e-05 tcagaagttc gagataag cctaaccaac chr3:45615766-45615846 1 3.76e-05 . gagataag caatactgaa chr8:21366960-21367040 33 3.76e-05 atgtggaaca gagataag ccatccaagc chr11:113953644-11395372 54 3.76e-05 GTGGCATGGG GAGATAAG GGCCCCAACG chr2:109830637-109830717 64 3.76e-05 aaaaccacaa gagataag atcacccaa chr1:201123014-201123094 22 4.81e-05 ACAGCCACCA AAGATAAG AGCTTCATGC chr2:121049509-121049589 27 4.81e-05 TGAATGTCTG AAGATAAG GGCTGTGCTC chr1:206908993-206909073 66 6.03e-05 cccagctggt gtgataag attgagc chr19:11244012-11244092 70 6.03e-05 GCAGGGAACC GTGATAAG CCT chr3:141765327-141765407 36 7.05e-05 TACAGAGGTA ATGATAAG AGAGATGGGA chr11:124146166-12414624 55 7.05e-05 CACTGGACTC ATGATAAG TAGAACACTG chr3:24561738-24561818 46 9.11e-05 TCTGAGGAGT CTGATAAA CCCGGAGGCA chr15:70384458-70384538 20 9.11e-05 AACAGGTCAG CTGATAAA CTTGTTTGCT chr5:52839380-52839460 70 1.01e-04 TCATCCCAGC TAGATAAG CAA chr2:197324418-197324498 35 1.11e-04 gcattccttc ttgataag agaccacaga chr8:74660219-74660299 63 1.34e-04 gcgccagagt cagataac caaggctgga chr10:43264390-43264470 64 1.43e-04 ttgcaaccct aagataaa cccctctcc chr6:43804457-43804537 42 1.43e-04 GCTTGTAGTC AAGATAAA GGGTCAGCTG chr1:220081003-220081083 23 1.43e-04 TCTGCTGAAG AAGATAAA CCCTGGGGGG chr1:8686608-8686688 31 1.43e-04 ttccaatcct aagataaa cccctctctg chr22:36876218-36876298 16 1.65e-04 ccggccGACA CTGATAAC TTTTTGCCAG chr1:206274320-206274400 42 1.65e-04 ccgtcctgtc ctgataac tgaccaccaa chr1:27371246-27371326 36 1.90e-04 GAAAAAGGGC CAGAGAAG CAGGTAGGCT chrX:153946223-153946303 2 1.90e-04 A CAGAGAAG GATGACGGCT chr11:65194724-65194804 25 2.20e-04 AGCCTCTGTG CTGAGAAG GAAGGTGCTT chr11:33906983-33907063 42 2.20e-04 CTCATGGGGG CAGATAGG AGGCCCAACA chr4:6927285-6927365 68 2.20e-04 AATGTGCTGA CAGATAGG TATCT chr8:30031471-30031551 30 2.28e-04 CAGCCTGTGG TAGATAAA GCTGGGAGGG chr3:141348933-141349013 39 2.56e-04 gcagcaagcc ctgatagg tgaagtctgc chr5:74677418-74677498 67 2.56e-04 AACGGCTTAA GAGATAAC TGTGGG chr20:3890858-3890938 69 2.74e-04 TGTTTGAAGG TTGATAAA TGCT chr7:135335818-135335898 63 3.13e-04 ACACTCCAAG GAGAGAAG GCCATAGAGT -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CWGATAAG MEME-3 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr19:8569207-8569287 1.3e-05 32_[+3]_40 chr5:10708849-10708929 1.3e-05 33_[+3]_39 chr19:39872629-39872709 1.3e-05 64_[+3]_8 chr19:33162868-33162948 1.3e-05 50_[+3]_22 chr6:34530798-34530878 1.3e-05 38_[+3]_34 chr17:36572790-36572870 1.3e-05 53_[+3]_19 chr17:60996882-60996962 2.5e-05 20_[+3]_52 chr3:131514381-131514461 2.5e-05 58_[+3]_14 chr6:2543230-2543310 2.5e-05 35_[+3]_37 chr1:162342672-162342752 2.5e-05 51_[+3]_21 chrX:107801625-107801705 2.5e-05 26_[+3]_46 chr6:25974324-25974404 2.5e-05 37_[+3]_35 chr17:72711397-72711477 2.5e-05 66_[+3]_6 chr9:101002920-101003000 2.5e-05 42_[+3]_30 chr9:111539305-111539385 2.5e-05 64_[+3]_8 chr14:100609049-10060912 3.8e-05 27_[+3]_45 chr1:234866552-234866632 3.8e-05 51_[+3]_21 chr10:43911139-43911219 3.8e-05 58_[+3]_14 chr3:45615766-45615846 3.8e-05 [+3]_72 chr8:21366960-21367040 3.8e-05 32_[+3]_40 chr11:113953644-11395372 3.8e-05 53_[+3]_19 chr2:109830637-109830717 3.8e-05 63_[+3]_9 chr1:201123014-201123094 4.8e-05 21_[+3]_51 chr2:121049509-121049589 4.8e-05 26_[+3]_46 chr1:206908993-206909073 6e-05 65_[+3]_7 chr19:11244012-11244092 6e-05 69_[+3]_3 chr3:141765327-141765407 7e-05 35_[+3]_37 chr11:124146166-12414624 7e-05 54_[+3]_18 chr3:24561738-24561818 9.1e-05 45_[+3]_27 chr15:70384458-70384538 9.1e-05 19_[+3]_53 chr5:52839380-52839460 0.0001 69_[+3]_3 chr2:197324418-197324498 0.00011 34_[+3]_38 chr8:74660219-74660299 0.00013 62_[+3]_10 chr10:43264390-43264470 0.00014 63_[+3]_9 chr6:43804457-43804537 0.00014 41_[+3]_31 chr1:220081003-220081083 0.00014 22_[+3]_50 chr1:8686608-8686688 0.00014 30_[+3]_42 chr22:36876218-36876298 0.00017 15_[+3]_57 chr1:206274320-206274400 0.00017 41_[+3]_31 chr1:27371246-27371326 0.00019 35_[+3]_37 chrX:153946223-153946303 0.00019 1_[+3]_71 chr11:65194724-65194804 0.00022 24_[+3]_48 chr11:33906983-33907063 0.00022 41_[+3]_31 chr4:6927285-6927365 0.00022 67_[+3]_5 chr8:30031471-30031551 0.00023 29_[+3]_43 chr3:141348933-141349013 0.00026 38_[+3]_34 chr5:74677418-74677498 0.00026 66_[+3]_6 chr20:3890858-3890938 0.00027 68_[+3]_4 chr7:135335818-135335898 0.00031 62_[+3]_10 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CWGATAAG MEME-3 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF CWGATAAG width=8 seqs=49 chr19:8569207-8569287 ( 33) CAGATAAG 1 chr5:10708849-10708929 ( 34) CAGATAAG 1 chr19:39872629-39872709 ( 65) CAGATAAG 1 chr19:33162868-33162948 ( 51) CAGATAAG 1 chr6:34530798-34530878 ( 39) CAGATAAG 1 chr17:36572790-36572870 ( 54) CAGATAAG 1 chr17:60996882-60996962 ( 21) CTGATAAG 1 chr3:131514381-131514461 ( 59) CTGATAAG 1 chr6:2543230-2543310 ( 36) CTGATAAG 1 chr1:162342672-162342752 ( 52) CTGATAAG 1 chrX:107801625-107801705 ( 27) CTGATAAG 1 chr6:25974324-25974404 ( 38) CTGATAAG 1 chr17:72711397-72711477 ( 67) CTGATAAG 1 chr9:101002920-101003000 ( 43) CTGATAAG 1 chr9:111539305-111539385 ( 65) CTGATAAG 1 chr14:100609049-10060912 ( 28) GAGATAAG 1 chr1:234866552-234866632 ( 52) GAGATAAG 1 chr10:43911139-43911219 ( 59) GAGATAAG 1 chr3:45615766-45615846 ( 1) GAGATAAG 1 chr8:21366960-21367040 ( 33) GAGATAAG 1 chr11:113953644-11395372 ( 54) GAGATAAG 1 chr2:109830637-109830717 ( 64) GAGATAAG 1 chr1:201123014-201123094 ( 22) AAGATAAG 1 chr2:121049509-121049589 ( 27) AAGATAAG 1 chr1:206908993-206909073 ( 66) GTGATAAG 1 chr19:11244012-11244092 ( 70) GTGATAAG 1 chr3:141765327-141765407 ( 36) ATGATAAG 1 chr11:124146166-12414624 ( 55) ATGATAAG 1 chr3:24561738-24561818 ( 46) CTGATAAA 1 chr15:70384458-70384538 ( 20) CTGATAAA 1 chr5:52839380-52839460 ( 70) TAGATAAG 1 chr2:197324418-197324498 ( 35) TTGATAAG 1 chr8:74660219-74660299 ( 63) CAGATAAC 1 chr10:43264390-43264470 ( 64) AAGATAAA 1 chr6:43804457-43804537 ( 42) AAGATAAA 1 chr1:220081003-220081083 ( 23) AAGATAAA 1 chr1:8686608-8686688 ( 31) AAGATAAA 1 chr22:36876218-36876298 ( 16) CTGATAAC 1 chr1:206274320-206274400 ( 42) CTGATAAC 1 chr1:27371246-27371326 ( 36) CAGAGAAG 1 chrX:153946223-153946303 ( 2) CAGAGAAG 1 chr11:65194724-65194804 ( 25) CTGAGAAG 1 chr11:33906983-33907063 ( 42) CAGATAGG 1 chr4:6927285-6927365 ( 68) CAGATAGG 1 chr8:30031471-30031551 ( 30) TAGATAAA 1 chr3:141348933-141349013 ( 39) CTGATAGG 1 chr5:74677418-74677498 ( 67) GAGATAAC 1 chr20:3890858-3890938 ( 69) TTGATAAA 1 chr7:135335818-135335898 ( 63) GAGAGAAG 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CWGATAAG MEME-3 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 9.65557 E= 7.8e-015 -49 95 -30 -143 132 -1226 -1226 96 -1226 -1226 186 -1226 212 -1226 -1226 -1226 -1226 -1226 -176 206 212 -1226 -1226 -1226 203 -1226 -217 -1226 -49 -175 145 -1226 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CWGATAAG MEME-3 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 49 E= 7.8e-015 0.163265 0.530612 0.224490 0.081633 0.571429 0.000000 0.000000 0.428571 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.081633 0.918367 1.000000 0.000000 0.000000 0.000000 0.938776 0.000000 0.061224 0.000000 0.163265 0.081633 0.755102 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CWGATAAG MEME-3 regular expression -------------------------------------------------------------------------------- [CG][AT]GATAAG -------------------------------------------------------------------------------- Time 11.94 secs. ******************************************************************************** ******************************************************************************** MOTIF CTTATCWG MEME-4 width = 8 sites = 25 llr = 225 E-value = 2.2e-002 ******************************************************************************** -------------------------------------------------------------------------------- Motif CTTATCWG MEME-4 Description -------------------------------------------------------------------------------- Simplified A ::2a::3: pos.-specific C 9::::a:1 probability G ::::::17 matrix T 1a8:a:62 bits 2.2 * ** 2.0 * *** 1.7 * *** 1.5 ****** Relative 1.3 ****** Entropy 1.1 ****** (13.0 bits) 0.9 ******* 0.7 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel CTTATCTG consensus AT sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTTATCWG MEME-4 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr12:4430057-4430137 43 1.12e-05 CGCCGGCTTC CTTATCTG CCCCGAACGC chr22:36876218-36876298 72 1.12e-05 TTAACATCAG CTTATCTG C chr1:12263819-12263899 31 1.12e-05 tcttggctga cttatctg ctcaccgcag chr17:40932222-40932302 49 1.12e-05 GTGGTGCTGC CTTATCTG GGGTGTGCAG chr10:6515514-6515594 9 1.12e-05 AAAAGAGG CTTATCTG TCACTACAGA chr1:201123014-201123094 39 2.29e-05 GAGCTTCATG CTTATCAG GCTTGCTGGG chr22:22465844-22465924 20 2.29e-05 TCCCCTCTCA CTTATCAG GTAGGGACAG chr16:69899741-69899821 28 2.29e-05 tcagtggcct cttatcag aaaggaatgc chr1:101251434-101251514 35 2.29e-05 ttggcggtct cttatcag gaaggaatgc chr6:90031434-90031514 41 2.29e-05 tcagtggtca cttatcag gaaggaatgc chr4:122911797-122911877 59 3.18e-05 atagaccagg cttatctt gcatacccac chr7:151092670-151092750 22 3.18e-05 ctgcggaccc cttatctt ggattcccag chr16:85411516-85411596 32 3.18e-05 GCCTCTCAGC CTTATCTT GGCCTTCTGC chr9:126817218-126817298 18 3.18e-05 GTTCTGAGTC CTTATCTT GGCCCTGGCC chr6:16224773-16224853 20 6.39e-05 tagtctaaag ctaatctg ttctgataga chr12:122087925-12208800 37 6.39e-05 aaaccaccgC CTTATCTC ATCCTCACAG chr7:150674126-150674206 26 6.39e-05 GGACATTTGC CTAATCTG GGACCCTTCT chr20:47654647-47654727 51 6.39e-05 AGGTTAACCT CTTATCTC TTGTCCCTCC chr3:133175004-133175084 54 8.69e-05 GGTCAGGAAC TTTATCTG AGCTGTAACC chr16:75109231-75109311 27 8.69e-05 CTCTGCACCC CTTATCGG AACTGCGGGT chr6:170404951-170405031 3 8.69e-05 CT CTTATCGG CCTTCTGCGG chr20:30263251-30263331 16 1.11e-04 ACGGAGAGGC CTTATCAC TCTTTTGGCA chr17:72711397-72711477 12 1.11e-04 CCCTCACACC CTAATCAG GAATGAGTGG chr2:16931603-16931683 16 1.20e-04 gaaccacacc ctaatctt ctcttctttt chr5:131450384-131450464 40 1.29e-04 ctacaacatc tttatcag ttactcccac -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTTATCWG MEME-4 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr12:4430057-4430137 1.1e-05 42_[+4]_30 chr22:36876218-36876298 1.1e-05 71_[+4]_1 chr1:12263819-12263899 1.1e-05 30_[+4]_42 chr17:40932222-40932302 1.1e-05 48_[+4]_24 chr10:6515514-6515594 1.1e-05 8_[+4]_64 chr1:201123014-201123094 2.3e-05 38_[+4]_34 chr22:22465844-22465924 2.3e-05 19_[+4]_53 chr16:69899741-69899821 2.3e-05 27_[+4]_45 chr1:101251434-101251514 2.3e-05 34_[+4]_38 chr6:90031434-90031514 2.3e-05 40_[+4]_32 chr4:122911797-122911877 3.2e-05 58_[+4]_14 chr7:151092670-151092750 3.2e-05 21_[+4]_51 chr16:85411516-85411596 3.2e-05 31_[+4]_41 chr9:126817218-126817298 3.2e-05 17_[+4]_55 chr6:16224773-16224853 6.4e-05 19_[+4]_53 chr12:122087925-12208800 6.4e-05 36_[+4]_36 chr7:150674126-150674206 6.4e-05 25_[+4]_47 chr20:47654647-47654727 6.4e-05 50_[+4]_22 chr3:133175004-133175084 8.7e-05 53_[+4]_19 chr16:75109231-75109311 8.7e-05 26_[+4]_46 chr6:170404951-170405031 8.7e-05 2_[+4]_70 chr20:30263251-30263331 0.00011 15_[+4]_57 chr17:72711397-72711477 0.00011 11_[+4]_61 chr2:16931603-16931683 0.00012 15_[+4]_57 chr5:131450384-131450464 0.00013 39_[+4]_33 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTTATCWG MEME-4 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF CTTATCWG width=8 seqs=25 chr12:4430057-4430137 ( 43) CTTATCTG 1 chr22:36876218-36876298 ( 72) CTTATCTG 1 chr1:12263819-12263899 ( 31) CTTATCTG 1 chr17:40932222-40932302 ( 49) CTTATCTG 1 chr10:6515514-6515594 ( 9) CTTATCTG 1 chr1:201123014-201123094 ( 39) CTTATCAG 1 chr22:22465844-22465924 ( 20) CTTATCAG 1 chr16:69899741-69899821 ( 28) CTTATCAG 1 chr1:101251434-101251514 ( 35) CTTATCAG 1 chr6:90031434-90031514 ( 41) CTTATCAG 1 chr4:122911797-122911877 ( 59) CTTATCTT 1 chr7:151092670-151092750 ( 22) CTTATCTT 1 chr16:85411516-85411596 ( 32) CTTATCTT 1 chr9:126817218-126817298 ( 18) CTTATCTT 1 chr6:16224773-16224853 ( 20) CTAATCTG 1 chr12:122087925-12208800 ( 37) CTTATCTC 1 chr7:150674126-150674206 ( 26) CTAATCTG 1 chr20:47654647-47654727 ( 51) CTTATCTC 1 chr3:133175004-133175084 ( 54) TTTATCTG 1 chr16:75109231-75109311 ( 27) CTTATCGG 1 chr6:170404951-170405031 ( 3) CTTATCGG 1 chr20:30263251-30263331 ( 16) CTTATCAC 1 chr17:72711397-72711477 ( 12) CTAATCAG 1 chr2:16931603-16931683 ( 16) CTAATCTT 1 chr5:131450384-131450464 ( 40) TTTATCAG 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTTATCWG MEME-4 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 11.1193 E= 2.2e-002 -1129 174 -1129 -146 -1129 -1129 -1129 219 -52 -1129 -1129 193 212 -1129 -1129 -1129 -1129 -1129 -1129 219 -1129 186 -1129 -1129 48 -1129 -178 145 -1129 -120 130 -14 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTTATCWG MEME-4 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 25 E= 2.2e-002 0.000000 0.920000 0.000000 0.080000 0.000000 0.000000 0.000000 1.000000 0.160000 0.000000 0.000000 0.840000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 0.320000 0.000000 0.080000 0.600000 0.000000 0.120000 0.680000 0.200000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTTATCWG MEME-4 regular expression -------------------------------------------------------------------------------- CTTATC[TA][GT] -------------------------------------------------------------------------------- Time 15.31 secs. ******************************************************************************** ******************************************************************************** MOTIF CTGCWGCY MEME-5 width = 8 sites = 34 llr = 276 E-value = 3.5e+002 ******************************************************************************** -------------------------------------------------------------------------------- Motif CTGCWGCY MEME-5 Description -------------------------------------------------------------------------------- Simplified A ::::5::: pos.-specific C 9:2a:3a4 probability G 1:8::7:: matrix T :a::5::6 bits 2.2 * 2.0 * * * 1.7 * * * 1.5 ** * * Relative 1.3 ** * * Entropy 1.1 ******** (11.7 bits) 0.9 ******** 0.7 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel CTGCAGCT consensus C TC C sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTGCWGCY MEME-5 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr5:10284223-10284303 35 1.76e-05 CGGCCACGCT CTGCAGCT CACGCACTAC chr22:23006443-23006523 26 1.76e-05 TGGGACAAGG CTGCAGCT GGGGAGACCA chr22:20810690-20810770 50 3.44e-05 AGCTGGAGAA CTGCTGCT TCCCCAGCTG chr15:39432277-39432357 18 3.44e-05 GCAGATGTGA CTGCTGCT CTGCTCGCCC chr22:22385028-22385108 44 3.44e-05 TGCTGTTGGT CTGCTGCT GAGGGCTCTG chr6:25974324-25974404 24 3.44e-05 ttagttgggc ctgctgct tagggtctga chr22:22465844-22465924 3 3.44e-05 CC CTGCTGCT CCCCTCTCAC chr6:2752292-2752372 4 3.44e-05 GGG CTGCTGCT GATCCAACCA chr3:13049195-13049275 3 3.44e-05 TG CTGCTGCT TGAAAGCCTC chr6:13381100-13381180 68 5.64e-05 AGGCTTCCTC CTGCAGCC CAGAA chr1:3691505-3691585 12 5.64e-05 TTATCAGGGG CTGCAGCC TAGATTGGGC chr10:105378630-10537871 49 5.64e-05 GGGGCCCTGT CTGCAGCC CTGTGCTGAG chrX:153031114-153031194 11 5.64e-05 GACATACAGG CTGCAGCC TCCCTCATGG chr1:145443031-145443111 4 5.64e-05 tca ctgcagcc ttgatttcct chr22:23088302-23088382 47 5.64e-05 GGCAGCAGAG CTGCAGCC AGGAGCTTTC chr7:155102380-155102460 73 7.75e-05 GGCAGCTTCC CTGCTGCC chr1:16469982-16470062 32 9.50e-05 GGCACAGTGG CTGCACCT CCGGCTATAC chr8:74660219-74660299 11 9.50e-05 AATCTCATGT CTGCACCT GGGAAGGTAG chr17:60996882-60996962 10 1.12e-04 TTCATTATT CTGCTCCT GTCCTGATAA chr10:96059364-96059444 68 1.29e-04 ATGGCCTTGT CTCCAGCT GAGGT chr3:167659496-167659576 28 1.29e-04 TTGCGGTTTC CTCCAGCT TCTTTGTGGT chr22:20749318-20749398 24 1.46e-04 cgctcctggc cTCCTGCT TCTTTCTTCC chr19:5691653-5691733 35 1.46e-04 AGCCCTGGCT CTCCTGCT GTCCGTGGGT chr17:31298336-31298416 60 1.68e-04 agaagacatg ctgcaccc aagctgggaa chr16:75109231-75109311 19 1.68e-04 TGATCGTTCT CTGCACCC CTTATCGGAA chr7:104771655-104771735 50 1.89e-04 GAAATGGCCC CTGCTCCC CGACTCCCAC chr1:222885479-222885559 47 1.89e-04 CCGGTCTGGC CTGCTCCC GCGGTTAGTC chr9:101002920-101003000 16 1.89e-04 TAACCAGGAA CTGCTCCC TCCCTGACAT chr19:12886465-12886545 3 2.11e-04 GC CTCCAGCC CCGCCATCTT chr1:247711569-247711649 2 2.32e-04 T CTCCTGCC GCTGATATTG chr5:133268509-133268589 6 2.49e-04 tcccc ctccacct ctgttcctgt chr3:133472785-133472865 22 2.84e-04 AGCAGGCTGT GTGCAGCT TGACCTGAAG chr12:113646077-11364615 13 2.84e-04 GTAGGTGTGA GTGCAGCT GTGCTGACAT chr3:5796488-5796568 13 3.01e-04 TCCCTGTATT gtgctgct caaagtgtca -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTGCWGCY MEME-5 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr5:10284223-10284303 1.8e-05 34_[+5]_38 chr22:23006443-23006523 1.8e-05 25_[+5]_47 chr22:20810690-20810770 3.4e-05 49_[+5]_23 chr15:39432277-39432357 3.4e-05 17_[+5]_55 chr22:22385028-22385108 3.4e-05 43_[+5]_29 chr6:25974324-25974404 3.4e-05 23_[+5]_49 chr22:22465844-22465924 3.4e-05 2_[+5]_70 chr6:2752292-2752372 3.4e-05 3_[+5]_69 chr3:13049195-13049275 3.4e-05 2_[+5]_70 chr6:13381100-13381180 5.6e-05 67_[+5]_5 chr1:3691505-3691585 5.6e-05 11_[+5]_61 chr10:105378630-10537871 5.6e-05 48_[+5]_24 chrX:153031114-153031194 5.6e-05 10_[+5]_62 chr1:145443031-145443111 5.6e-05 3_[+5]_69 chr22:23088302-23088382 5.6e-05 46_[+5]_26 chr7:155102380-155102460 7.7e-05 72_[+5] chr1:16469982-16470062 9.5e-05 31_[+5]_41 chr8:74660219-74660299 9.5e-05 10_[+5]_62 chr17:60996882-60996962 0.00011 9_[+5]_63 chr10:96059364-96059444 0.00013 67_[+5]_5 chr3:167659496-167659576 0.00013 27_[+5]_45 chr22:20749318-20749398 0.00015 23_[+5]_49 chr19:5691653-5691733 0.00015 34_[+5]_38 chr17:31298336-31298416 0.00017 59_[+5]_13 chr16:75109231-75109311 0.00017 18_[+5]_54 chr7:104771655-104771735 0.00019 49_[+5]_23 chr1:222885479-222885559 0.00019 46_[+5]_26 chr9:101002920-101003000 0.00019 15_[+5]_57 chr19:12886465-12886545 0.00021 2_[+5]_70 chr1:247711569-247711649 0.00023 1_[+5]_71 chr5:133268509-133268589 0.00025 5_[+5]_67 chr3:133472785-133472865 0.00028 21_[+5]_51 chr12:113646077-11364615 0.00028 12_[+5]_60 chr3:5796488-5796568 0.0003 12_[+5]_60 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTGCWGCY MEME-5 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF CTGCWGCY width=8 seqs=34 chr5:10284223-10284303 ( 35) CTGCAGCT 1 chr22:23006443-23006523 ( 26) CTGCAGCT 1 chr22:20810690-20810770 ( 50) CTGCTGCT 1 chr15:39432277-39432357 ( 18) CTGCTGCT 1 chr22:22385028-22385108 ( 44) CTGCTGCT 1 chr6:25974324-25974404 ( 24) CTGCTGCT 1 chr22:22465844-22465924 ( 3) CTGCTGCT 1 chr6:2752292-2752372 ( 4) CTGCTGCT 1 chr3:13049195-13049275 ( 3) CTGCTGCT 1 chr6:13381100-13381180 ( 68) CTGCAGCC 1 chr1:3691505-3691585 ( 12) CTGCAGCC 1 chr10:105378630-10537871 ( 49) CTGCAGCC 1 chrX:153031114-153031194 ( 11) CTGCAGCC 1 chr1:145443031-145443111 ( 4) CTGCAGCC 1 chr22:23088302-23088382 ( 47) CTGCAGCC 1 chr7:155102380-155102460 ( 73) CTGCTGCC 1 chr1:16469982-16470062 ( 32) CTGCACCT 1 chr8:74660219-74660299 ( 11) CTGCACCT 1 chr17:60996882-60996962 ( 10) CTGCTCCT 1 chr10:96059364-96059444 ( 68) CTCCAGCT 1 chr3:167659496-167659576 ( 28) CTCCAGCT 1 chr22:20749318-20749398 ( 24) CTCCTGCT 1 chr19:5691653-5691733 ( 35) CTCCTGCT 1 chr17:31298336-31298416 ( 60) CTGCACCC 1 chr16:75109231-75109311 ( 19) CTGCACCC 1 chr7:104771655-104771735 ( 50) CTGCTCCC 1 chr1:222885479-222885559 ( 47) CTGCTCCC 1 chr9:101002920-101003000 ( 16) CTGCTCCC 1 chr19:12886465-12886545 ( 3) CTCCAGCC 1 chr1:247711569-247711649 ( 2) CTCCTGCC 1 chr5:133268509-133268589 ( 6) CTCCACCT 1 chr3:133472785-133472865 ( 22) GTGCAGCT 1 chr12:113646077-11364615 ( 13) GTGCAGCT 1 chr3:5796488-5796568 ( 13) GTGCTGCT 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTGCWGCY MEME-5 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 9.13512 E= 3.5e+002 -1173 173 -164 -1173 -1173 -1173 -1173 219 -1173 -42 152 -1173 -1173 186 -1173 -1173 121 -1173 -1173 110 -1173 -5 141 -1173 -1173 186 -1173 -1173 -1173 58 -1173 142 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTGCWGCY MEME-5 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 34 E= 3.5e+002 0.000000 0.911765 0.088235 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.205882 0.794118 0.000000 0.000000 1.000000 0.000000 0.000000 0.529412 0.000000 0.000000 0.470588 0.000000 0.264706 0.735294 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.411765 0.000000 0.588235 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTGCWGCY MEME-5 regular expression -------------------------------------------------------------------------------- CT[GC]C[AT][GC]C[TC] -------------------------------------------------------------------------------- Time 18.62 secs. ******************************************************************************** ******************************************************************************** SUMMARY OF MOTIFS ******************************************************************************** -------------------------------------------------------------------------------- Combined block diagrams: non-overlapping sites with p-value < 0.0001 -------------------------------------------------------------------------------- SEQUENCE NAME COMBINED P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr10:5593769-5593849 1.15e-01 30_[+1(4.08e-05)]_12_[+1(4.08e-05)]_\ 22 chr5:74677418-74677498 2.54e-03 27_[+1(2.57e-05)]_45 chr17:4110422-4110502 5.70e-02 9_[+1(1.26e-05)]_16_[+1(1.26e-05)]_\ 16_[+1(1.26e-05)]_15 chr1:165362392-165362472 8.30e-02 41_[+2(4.13e-05)]_6_[+2(4.13e-05)]_\ 17 chr11:120215191-12021527 1.96e-02 13_[+2(2.44e-05)]_15_[+2(1.35e-05)]_\ 36 chr7:127684242-127684322 6.22e-03 39_[+2(2.44e-05)]_33 chr14:100288194-10028827 1.67e-05 9_[+1(1.26e-05)]_21_[+2(1.35e-05)]_\ 34 chr2:109830637-109830717 1.17e-04 54_[+1(2.57e-05)]_1_[+3(3.76e-05)]_\ 9 chr8:142046309-142046389 6.59e-02 80 chr6:170404951-170405031 9.06e-03 2_[+4(8.69e-05)]_24_[+2(5.49e-05)]_\ 38 chr1:246588567-246588647 1.09e-02 80 chr22:19969518-19969598 1.93e-01 80 chr8:42074684-42074764 4.74e-04 53_[+3(1.27e-05)]_19 chr1:16478045-16478125 1.03e-01 80 chr9:126817218-126817298 3.27e-04 17_[+4(3.18e-05)]_18_[+2(1.35e-05)]_\ 29 chr9:111539305-111539385 8.22e-05 27_[+2(2.44e-05)]_29_[+3(2.48e-05)]_\ 8 chr2:197324418-197324498 2.79e-03 42_[+1(5.66e-05)]_30 chr6:90031434-90031514 6.45e-04 40_[+4(2.29e-05)]_32 chr3:130506665-130506745 2.20e-02 40_[+2(8.53e-05)]_5_[+2(7.18e-05)]_\ 19 chrX:48794395-48794475 3.85e-02 80 chr7:142506649-142506729 2.88e-03 71_[+1(8.81e-05)]_1 chr20:47654647-47654727 2.83e-03 50_[+4(6.39e-05)]_22 chr10:82532454-82532534 4.45e-01 80 chr11:72526278-72526358 6.73e-05 34_[+2(1.35e-05)]_7_[+1(1.26e-05)]_\ 23 chr7:155102380-155102460 1.78e-02 72_[+5(7.75e-05)] chr19:8634117-8634197 1.49e-03 27_[+2(5.49e-05)]_5_[+1(4.08e-05)]_\ 32 chr3:5796488-5796568 1.31e-03 50_[+1(2.57e-05)]_22 chr5:55788787-55788867 4.90e-04 19_[+2(4.13e-05)]_4_[+2(1.35e-05)]_\ 41 chr22:22053371-22053451 5.22e-01 80 chr11:46358479-46358559 4.02e-03 80 chr17:47438816-47438896 2.39e-01 80 chr9:101002920-101003000 4.01e-04 42_[+3(2.48e-05)]_30 chr7:91763135-91763215 4.30e-03 45_[+1(7.24e-05)]_27 chr13:114035492-11403557 8.14e-02 33_[+1(4.08e-05)]_14_[+1(4.08e-05)]_\ 17 chr1:101251434-101251514 3.52e-05 18_[+2(1.35e-05)]_8_[+4(2.29e-05)]_\ 38 chr17:36572790-36572870 7.06e-03 53_[+3(1.27e-05)]_19 chr22:23197983-23198063 5.92e-01 80 chr8:74660219-74660299 5.81e-04 10_[+5(9.50e-05)]_62 chr17:72711397-72711477 1.29e-05 54_[+1(2.57e-05)]_4_[+3(2.48e-05)]_\ 6 chr3:13049195-13049275 6.25e-04 2_[+5(3.44e-05)]_49_[+2(7.18e-05)]_\ 13 chr6:2974088-2974168 5.85e-03 20_[+2(2.44e-05)]_52 chr17:25871771-25871851 3.61e-01 80 chr22:23226273-23226353 6.39e-01 80 chr2:232410376-232410456 3.48e-04 36_[+1(4.08e-05)]_36 chr22:21804773-21804853 1.39e-01 80 chr22:23088302-23088382 1.15e-02 46_[+5(5.64e-05)]_26 chr4:6927285-6927365 2.89e-03 27_[+2(1.35e-05)]_45 chr10:100538206-10053828 5.31e-01 80 chr22:22937138-22937218 4.47e-01 80 chr2:54798219-54798299 2.76e-01 80 chr3:126627725-126627805 6.71e-02 26_[+2(1.35e-05)]_46 chr12:110531903-11053198 3.97e-04 62_[+4(3.18e-05)]_10 chr6:71021976-71022056 4.04e-02 17_[+1(1.26e-05)]_[+1(2.57e-05)]_35_\ [+1(7.24e-05)]_4 chrX:153946223-153946303 2.23e-04 41_[+2(1.35e-05)]_31 chr5:52839380-52839460 2.03e-05 3_[+1(4.08e-05)]_6_[+2(2.44e-05)]_\ 55 chr2:121049509-121049589 4.15e-03 3_[+2(2.44e-05)]_15_[+3(4.81e-05)]_\ 46 chr11:70270384-70270464 3.29e-02 31_[+2(4.13e-05)]_41 chr5:66502916-66502996 1.65e-03 2_[+2(1.35e-05)]_32_[+2(7.18e-05)]_\ 30 chr7:150674126-150674206 1.38e-01 25_[+4(6.39e-05)]_47 chr2:20624732-20624812 1.32e-02 21_[+2(7.18e-05)]_51 chr19:54714723-54714803 1.00e-02 36_[+1(1.26e-05)]_36 chr9:124813831-124813911 4.32e-03 17_[+1(4.08e-05)]_55 chr2:64582049-64582129 1.26e-01 11_[+1(7.24e-05)]_61 chr1:218550823-218550903 1.91e-04 18_[+1(1.26e-05)]_54 chr3:155546441-155546521 1.97e-04 71_[+1(5.66e-05)]_1 chr8:141640633-141640713 1.93e-02 55_[+1(7.24e-05)]_17 chr6:107268390-107268470 4.27e-02 35_[+1(4.08e-05)]_37 chr11:65195939-65196019 8.08e-01 80 chr6:2752292-2752372 1.08e-03 3_[+5(3.44e-05)]_4_[+1(7.24e-05)]_\ 57 chr12:94483804-94483884 5.23e-03 41_[+2(7.18e-05)]_31 chr11:18715085-18715165 3.28e-02 37_[+1(2.57e-05)]_35 chr22:23378951-23379031 3.45e-01 80 chr17:57920555-57920635 2.68e-01 80 chr16:69899741-69899821 1.57e-04 3_[+1(8.81e-05)]_16_[+4(2.29e-05)]_\ 28_[+1(2.57e-05)]_9 chr19:41769058-41769138 3.66e-01 80 chr6:34530798-34530878 7.98e-03 38_[+3(1.27e-05)]_34 chr11:113953644-11395372 2.20e-03 5_[+2(4.13e-05)]_40_[+3(3.76e-05)]_\ 19 chr10:127293925-12729400 4.20e-02 80 chr12:90127536-90127616 1.92e-02 11_[+2(2.44e-05)]_61 chr22:22465844-22465924 3.01e-04 2_[+5(3.44e-05)]_9_[+4(2.29e-05)]_\ 53 chr16:85411516-85411596 2.03e-02 31_[+4(3.18e-05)]_41 chr22:19629750-19629830 4.88e-01 80 chr11:33906983-33907063 1.23e-03 80 chr19:33162868-33162948 3.18e-04 23_[+2(5.49e-05)]_19_[+3(1.27e-05)]_\ 22 chr21:43885725-43885805 5.20e-02 52_[+1(1.26e-05)]_20 chr8:30031471-30031551 2.13e-02 80 chr11:124146166-12414624 1.87e-02 54_[+3(7.05e-05)]_18 chr6:25974324-25974404 2.39e-04 23_[+5(3.44e-05)]_6_[+3(2.48e-05)]_\ 35 chr22:36864185-36864265 1.10e-03 15_[+1(1.26e-05)]_57 chr9:139129834-139129914 1.11e-02 55_[+1(1.26e-05)]_17 chr17:56406893-56406973 5.26e-01 80 chr1:24648870-24648950 3.89e-03 32_[+2(1.35e-05)]_[+2(5.49e-05)]_32 chr22:23006443-23006523 2.83e-03 25_[+5(1.76e-05)]_15_[+1(7.24e-05)]_\ 24 chr19:5691653-5691733 6.57e-02 80 chr15:70384458-70384538 1.25e-02 19_[+3(9.11e-05)]_53 chr16:9085987-9086067 7.30e-01 80 chr12:113646077-11364615 1.45e-03 53_[+1(2.57e-05)]_19 chr22:23262435-23262515 7.40e-01 80 chr1:95100667-95100747 3.42e-02 80 chr3:47388853-47388933 3.33e-03 60_[+2(1.35e-05)]_12 chr11:876042-876122 2.44e-01 80 chr17:40903161-40903241 6.29e-02 80 chr8:21366960-21367040 7.19e-03 32_[+3(3.76e-05)]_29_[+1(8.81e-05)]_\ 3 chr1:8918312-8918392 5.62e-02 80 chr3:32750982-32751062 2.42e-03 50_[+2(1.35e-05)]_22 chr22:20749318-20749398 1.96e-01 80 chr3:167659496-167659576 8.04e-03 17_[+2(8.53e-05)]_13_[+2(2.44e-05)]_\ 34 chr7:50626284-50626364 3.56e-02 57_[+1(4.08e-05)]_15 chr12:122087925-12208800 2.19e-03 36_[+4(6.39e-05)]_14_[+1(1.26e-05)]_\ 14 chr1:207989323-207989403 7.95e-04 61_[+2(5.49e-05)]_3_[+1(2.57e-05)] chr3:24561738-24561818 2.20e-02 45_[+3(9.11e-05)]_27 chr22:39632592-39632672 1.93e-01 80 chr10:49676378-49676458 3.86e-02 55_[+1(4.08e-05)]_17 chr19:12886465-12886545 3.07e-01 80 chr10:6515514-6515594 2.83e-02 8_[+4(1.12e-05)]_64 chr15:80446410-80446490 2.23e-02 21_[+2(2.44e-05)]_51 chr10:105264217-10526429 6.42e-02 11_[+1(5.66e-05)]_61 chr19:11244012-11244092 1.17e-01 69_[+3(6.03e-05)]_3 chr2:16931603-16931683 6.21e-03 5_[+1(8.81e-05)]_67 chr2:17314469-17314549 6.17e-02 80 chr1:145443031-145443111 7.93e-02 3_[+5(5.64e-05)]_69 chr19:39872629-39872709 5.75e-03 64_[+3(1.27e-05)]_8 chr5:10284223-10284303 9.90e-03 34_[+5(1.76e-05)]_38 chr5:95220395-95220475 1.98e-02 29_[+2(4.13e-05)]_43 chr16:75109231-75109311 7.92e-04 26_[+4(8.69e-05)]_46 chr6:28534094-28534174 1.39e-02 80 chr6:16224773-16224853 6.16e-04 19_[+4(6.39e-05)]_53 chr20:30263251-30263331 5.37e-03 68_[+2(2.44e-05)]_4 chr1:222885479-222885559 7.16e-02 80 chr5:55457907-55457987 5.19e-02 32_[+2(4.13e-05)]_40 chr6:43855888-43855968 8.39e-01 80 chr12:65114778-65114858 3.92e-01 80 chr6:52166274-52166354 5.99e-02 65_[+1(4.08e-05)]_7 chr22:43659962-43660042 1.25e-01 80 chr22:22385028-22385108 1.55e-02 43_[+5(3.44e-05)]_29 chr1:12043659-12043739 4.12e-02 80 chr22:20255925-20256005 3.45e-01 80 chr4:140187965-140188045 1.93e-02 59_[+2(4.13e-05)]_13 chr3:141765327-141765407 8.62e-03 6_[+2(4.13e-05)]_21_[+3(7.05e-05)]_\ 37 chr17:74381731-74381811 5.65e-01 80 chr6:17600487-17600567 1.16e-01 53_[+2(7.18e-05)]_19 chr15:50552894-50552974 3.02e-03 44_[+2(4.13e-05)]_28 chr17:56413377-56413457 4.45e-02 80 chr22:23252961-23253041 1.12e-01 80 chr10:96059364-96059444 1.78e-03 47_[+1(2.57e-05)]_25 chr2:133015192-133015272 2.12e-01 80 chr13:22562089-22562169 2.90e-02 80 chr1:19239671-19239751 6.79e-01 80 chrX:153031114-153031194 2.63e-02 10_[+5(5.64e-05)]_62 chr5:10708849-10708929 8.23e-03 33_[+3(1.27e-05)]_39 chrX:107801625-107801705 6.59e-02 26_[+3(2.48e-05)]_46 chr19:39048048-39048128 5.63e-01 80 chr19:8569207-8569287 6.20e-05 32_[+3(1.27e-05)]_9_[+1(4.08e-05)]_\ 23 chr5:131450384-131450464 1.20e-03 71_[+1(2.57e-05)]_1 chr1:206908993-206909073 1.72e-05 37_[+2(4.13e-05)]_20_[+3(6.03e-05)]_\ 7 chr11:65194724-65194804 5.08e-02 80 chr22:23450841-23450921 2.63e-01 80 chr17:40932222-40932302 2.60e-03 48_[+4(1.12e-05)]_24 chr22:22313504-22313584 5.28e-02 80 chr22:20941634-20941714 5.89e-01 80 chr6:15211463-15211543 5.74e-01 80 chr22:20285391-20285471 4.37e-01 80 chr1:8686608-8686688 4.36e-03 8_[+1(7.24e-05)]_30_[+1(4.08e-05)]_\ 26 chr1:220081003-220081083 3.55e-04 56_[+1(2.57e-05)]_16 chr3:16977887-16977967 2.28e-01 80 chr20:46008628-46008708 9.22e-01 80 chr5:133268509-133268589 1.69e-03 80 chr15:89545664-89545744 3.89e-02 61_[+1(2.57e-05)]_11 chr10:76995161-76995241 7.71e-01 80 chr2:152991634-152991714 3.70e-03 31_[+2(1.35e-05)]_41 chr4:79542717-79542797 6.89e-02 1_[+1(4.08e-05)]_71 chr7:26228401-26228481 1.68e-01 80 chr17:56743872-56743952 1.78e-01 80 chr3:45615766-45615846 3.96e-04 [+3(3.76e-05)]_14_[+2(8.53e-05)]_50 chr1:148604888-148604968 3.41e-01 80 chr1:22743214-22743294 2.66e-01 80 chr1:162342672-162342752 6.28e-04 51_[+3(2.48e-05)]_21 chr6:2543230-2543310 1.64e-05 6_[+2(2.44e-05)]_21_[+3(2.48e-05)]_\ 7_[+1(7.24e-05)]_22 chr1:16469982-16470062 3.82e-02 31_[+5(9.50e-05)]_41 chr10:43911139-43911219 2.19e-02 58_[+3(3.76e-05)]_14 chr3:185694888-185694968 7.74e-03 20_[+1(2.57e-05)]_52 chr17:31298336-31298416 5.54e-02 80 chr7:765349-765429 4.97e-02 80 chr11:61731347-61731427 8.07e-01 80 chr1:28199502-28199582 1.67e-01 80 chr6:28303865-28303945 1.50e-01 80 chr22:23449902-23449982 4.95e-01 80 chr1:206274320-206274400 1.71e-02 80 chr7:104771655-104771735 4.62e-03 14_[+2(5.49e-05)]_58 chr11:61687769-61687849 3.25e-01 80 chr22:23239670-23239750 5.95e-01 80 chr22:19006740-19006820 1.98e-01 80 chr21:46494119-46494199 7.71e-01 80 chr22:20885053-20885133 3.72e-01 80 chr20:3890858-3890938 1.58e-02 80 chr1:234866552-234866632 1.02e-02 51_[+3(3.76e-05)]_21 chr7:135335818-135335898 2.83e-02 80 chr6:36922157-36922237 3.49e-03 4_[+2(1.35e-05)]_68 chr10:105378630-10537871 5.89e-03 48_[+5(5.64e-05)]_24 chr1:172715569-172715649 9.17e-03 38_[+2(8.53e-05)]_34 chr1:27371246-27371326 1.65e-02 80 chr1:12263819-12263899 1.41e-03 30_[+4(1.12e-05)]_42 chr3:133175004-133175084 4.94e-03 53_[+4(8.69e-05)]_19 chr1:3691505-3691585 3.14e-03 11_[+5(5.64e-05)]_61 chr22:36876218-36876298 1.40e-04 39_[+2(8.53e-05)]_24_[+4(1.12e-05)]_\ 1 chr19:41104593-41104673 1.59e-01 80 chr2:15870767-15870847 1.77e-02 50_[+2(7.18e-05)]_22 chr1:19147274-19147354 2.85e-01 80 chr6:43804457-43804537 6.01e-03 56_[+2(1.35e-05)]_16 chr7:139935114-139935194 5.45e-01 80 chr6:13355811-13355891 3.71e-01 80 chr16:66558871-66558951 2.54e-02 24_[+2(1.35e-05)]_48 chr22:20144562-20144642 7.42e-01 80 chr2:169952261-169952341 9.45e-03 22_[+1(1.26e-05)]_50 chr7:151092670-151092750 1.51e-02 21_[+4(3.18e-05)]_51 chr3:141348933-141349013 4.65e-03 80 chr2:30476947-30477027 4.69e-04 60_[+1(2.57e-05)]_12 chr15:82237467-82237547 1.64e-02 80 chr12:4430057-4430137 2.89e-03 16_[+1(7.24e-05)]_18_[+4(1.12e-05)]_\ 30 chr7:142502496-142502576 8.19e-02 80 chr11:46563394-46563474 1.36e-01 80 chr17:39834958-39835038 4.47e-01 80 chr16:58299539-58299619 4.25e-03 80 chr3:133472785-133472865 1.72e-03 80 chr22:22454821-22454901 4.08e-01 80 chr1:201123014-201123094 1.49e-04 21_[+3(4.81e-05)]_9_[+4(2.29e-05)]_\ 34 chr15:39432277-39432357 4.73e-04 17_[+5(3.44e-05)]_14_[+3(6.03e-05)]_\ 33 chr6:13381100-13381180 1.81e-02 67_[+5(5.64e-05)]_5 chr22:20810690-20810770 3.45e-03 49_[+5(3.44e-05)]_23 chr1:247711569-247711649 9.16e-03 80 chr11:63862129-63862209 2.07e-03 50_[+1(4.08e-05)]_22 chr2:159986996-159987076 5.86e-02 31_[+2(2.44e-05)]_41 chr5:177844567-177844647 1.67e-02 14_[+1(2.57e-05)]_58 chr14:100609049-10060912 2.10e-01 27_[+3(3.76e-05)]_45 chr4:122911797-122911877 5.45e-04 58_[+4(3.18e-05)]_14 chr3:131514381-131514461 5.97e-06 21_[+2(2.44e-05)]_29_[+3(2.48e-05)]_\ [+1(5.66e-05)]_6 chr11:62618969-62619049 8.08e-01 80 chr12:53764905-53764985 9.12e-01 80 chr21:46494996-46495076 7.20e-01 80 chr17:60996882-60996962 1.25e-04 20_[+3(2.48e-05)]_52 chr15:70740421-70740501 1.65e-01 80 chr9:139568717-139568797 1.26e-01 80 chr22:19183448-19183528 2.47e-01 80 chr18:11925946-11926026 4.49e-03 32_[+2(2.44e-05)]_26_[+2(2.44e-05)]_\ 6 chr7:101372839-101372919 8.48e-02 80 chr6:43753137-43753217 1.04e-01 80 chr2:28578546-28578626 5.98e-03 80 chr10:43264390-43264470 2.37e-03 22_[+1(2.57e-05)]_50 chr1:11847431-11847511 4.87e-02 80 chr19:49939935-49940015 6.84e-01 80 -------------------------------------------------------------------------------- ******************************************************************************** ******************************************************************************** Stopped because requested number of motifs (5) found. ******************************************************************************** CPU: c22n04.farnam.hpc.yale.internal ********************************************************************************