******************************************************************************** MEME - Motif discovery tool ******************************************************************************** MEME version 5.3.3 (Release date: Sun Feb 7 15:39:52 2021 -0800) For further information on how to interpret these results please access https://meme-suite.org/meme. To get a copy of the MEME Suite software please access https://meme-suite.org. ******************************************************************************** ******************************************************************************** REFERENCE ******************************************************************************** If you use this program in your research, please cite: Timothy L. Bailey and Charles Elkan, "Fitting a mixture model by expectation maximization to discover motifs in biopolymers", Proceedings of the Second International Conference on Intelligent Systems for Molecular Biology, pp. 28-36, AAAI Press, Menlo Park, California, 1994. ******************************************************************************** ******************************************************************************** TRAINING SET ******************************************************************************** PRIMARY SEQUENCES= ../result/final_prediction/K562/fasta/RankLinear0.6_40/RLF.fasta CONTROL SEQUENCES= --none-- ALPHABET= ACGT Sequence name Weight Length Sequence name Weight Length ------------- ------ ------ ------------- ------ ------ chr7:65112472-65112552 1.0000 80 chr7:64601230-64601310 1.0000 80 chr7:64974272-64974352 1.0000 80 chr1:121138464-121138544 1.0000 80 chr16:32127586-32127666 1.0000 80 chr19:4585038-4585118 1.0000 80 chr19:40910015-40910095 1.0000 80 chr12:57853645-57853725 1.0000 80 chr14:106765289-10676536 1.0000 80 chr5:108906321-108906401 1.0000 80 chr2:132796274-132796354 1.0000 80 chr7:302918-302998 1.0000 80 chr6:16238537-16238617 1.0000 80 chr16:15743852-15743932 1.0000 80 chr20:1247315-1247395 1.0000 80 chr3:170626229-170626309 1.0000 80 chr19:1249961-1250041 1.0000 80 chr14:106873621-10687370 1.0000 80 chr19:35455058-35455138 1.0000 80 chr19:17403085-17403165 1.0000 80 chr15:22461192-22461272 1.0000 80 chr7:303693-303773 1.0000 80 chr6:12013216-12013296 1.0000 80 chr19:14168202-14168282 1.0000 80 chr1:109791947-109792027 1.0000 80 chr17:41174283-41174363 1.0000 80 chr19:566596-566676 1.0000 80 chr17:81153469-81153549 1.0000 80 chr10:17496690-17496770 1.0000 80 chr22:19157215-19157295 1.0000 80 chr7:106656902-106656982 1.0000 80 chr2:114361704-114361784 1.0000 80 chr12:108522901-10852298 1.0000 80 chr16:88905532-88905612 1.0000 80 chr17:47308065-47308145 1.0000 80 chr9:33167033-33167113 1.0000 80 chr5:79704186-79704266 1.0000 80 chr7:64974768-64974848 1.0000 80 chr19:39465867-39465947 1.0000 80 chr19:2475705-2475785 1.0000 80 chr19:11650762-11650842 1.0000 80 chr1:121138663-121138743 1.0000 80 chr16:85361990-85362070 1.0000 80 chr6:138725119-138725199 1.0000 80 chr5:154062529-154062609 1.0000 80 chr10:73078802-73078882 1.0000 80 chr16:33040174-33040254 1.0000 80 chr15:96900421-96900501 1.0000 80 chr16:85202388-85202468 1.0000 80 chr20:30196422-30196502 1.0000 80 chr12:118810498-11881057 1.0000 80 chr3:20081534-20081614 1.0000 80 chr22:25201894-25201974 1.0000 80 chrX:122648192-122648272 1.0000 80 chr7:103630442-103630522 1.0000 80 chr1:45750685-45750765 1.0000 80 chr17:42402493-42402573 1.0000 80 chr5:149109884-149109964 1.0000 80 chr4:2956819-2956899 1.0000 80 chr19:13905743-13905823 1.0000 80 chrX:10087674-10087754 1.0000 80 chr16:86609640-86609720 1.0000 80 chr7:98822052-98822132 1.0000 80 chr1:41267903-41267983 1.0000 80 chr6:32223190-32223270 1.0000 80 chr19:10527117-10527197 1.0000 80 chr22:29702521-29702601 1.0000 80 chr6:148646-148726 1.0000 80 chr22:39541986-39542066 1.0000 80 chr1:27929842-27929922 1.0000 80 chr16:11391500-11391580 1.0000 80 chr1:145209834-145209914 1.0000 80 chr11:85565806-85565886 1.0000 80 chr1:117909227-117909307 1.0000 80 chr9:132259037-132259117 1.0000 80 chr6:111580791-111580871 1.0000 80 chr12:32112197-32112277 1.0000 80 chr2:91670338-91670418 1.0000 80 chr20:45317804-45317884 1.0000 80 chr6:84743887-84743967 1.0000 80 chr5:150603404-150603484 1.0000 80 chr3:152878708-152878788 1.0000 80 chr21:38739308-38739388 1.0000 80 chr3:196366878-196366958 1.0000 80 chr16:33619142-33619222 1.0000 80 chr19:7716989-7717069 1.0000 80 chr1:211752338-211752418 1.0000 80 chr1:12079712-12079792 1.0000 80 chr5:61602446-61602526 1.0000 80 chr16:68119445-68119525 1.0000 80 chr1:90099099-90099179 1.0000 80 chr19:47750726-47750806 1.0000 80 chr15:22462158-22462238 1.0000 80 chr3:10206731-10206811 1.0000 80 chr19:10025594-10025674 1.0000 80 chr3:138663915-138663995 1.0000 80 chr16:67597155-67597235 1.0000 80 chr1:185015056-185015136 1.0000 80 chr1:32713866-32713946 1.0000 80 chr19:48113509-48113589 1.0000 80 chr2:179278380-179278460 1.0000 80 chr6:34359706-34359786 1.0000 80 chr10:51572501-51572581 1.0000 80 chr4:123843662-123843742 1.0000 80 chr11:190029-190109 1.0000 80 chr15:40615662-40615742 1.0000 80 chr16:28858200-28858280 1.0000 80 chr6:157041082-157041162 1.0000 80 chr15:96874168-96874248 1.0000 80 chr9:132199410-132199490 1.0000 80 chr6:86388906-86388986 1.0000 80 chr19:18229036-18229116 1.0000 80 chr5:177557655-177557735 1.0000 80 chrX:19003048-19003128 1.0000 80 chr8:21999575-21999655 1.0000 80 chr7:112726700-112726780 1.0000 80 chr17:4901025-4901105 1.0000 80 chr17:40706645-40706725 1.0000 80 chr19:14142722-14142802 1.0000 80 chr7:149570512-149570592 1.0000 80 chr2:30934647-30934727 1.0000 80 chr3:197476353-197476433 1.0000 80 chr9:33677270-33677350 1.0000 80 chr5:180258148-180258228 1.0000 80 chr19:3388830-3388910 1.0000 80 chr22:22652176-22652256 1.0000 80 chr19:610878-610958 1.0000 80 chr6:33247909-33247989 1.0000 80 chr17:46178596-46178676 1.0000 80 chrX:71792815-71792895 1.0000 80 chr1:227505934-227506014 1.0000 80 chr4:90032809-90032889 1.0000 80 chr11:64795035-64795115 1.0000 80 chr11:33280017-33280097 1.0000 80 chr6:17987097-17987177 1.0000 80 chr19:1512820-1512900 1.0000 80 chr1:22109213-22109293 1.0000 80 chr7:73081816-73081896 1.0000 80 chr1:150521383-150521463 1.0000 80 chr16:3314064-3314144 1.0000 80 chr2:43451419-43451499 1.0000 80 chr4:113153157-113153237 1.0000 80 chr1:23895029-23895109 1.0000 80 chr19:47017015-47017095 1.0000 80 chr7:138793942-138794022 1.0000 80 chr10:97051183-97051263 1.0000 80 chr1:28696534-28696614 1.0000 80 chr7:2599068-2599148 1.0000 80 chr11:67275347-67275427 1.0000 80 chr3:20082230-20082310 1.0000 80 chr10:114206759-11420683 1.0000 80 chr11:17375105-17375185 1.0000 80 chr13:114103642-11410372 1.0000 80 chr7:8008583-8008663 1.0000 80 chr7:148787588-148787668 1.0000 80 chr19:9879072-9879152 1.0000 80 chr1:108742601-108742681 1.0000 80 chr1:145209074-145209154 1.0000 80 chr11:86666170-86666250 1.0000 80 chr17:62915814-62915894 1.0000 80 chr19:1676022-1676102 1.0000 80 chr12:125230699-12523077 1.0000 80 chr6:4647937-4648017 1.0000 80 chr3:195475042-195475122 1.0000 80 chr19:633960-634040 1.0000 80 chr3:15247968-15248048 1.0000 80 chr19:2282030-2282110 1.0000 80 chr7:32767643-32767723 1.0000 80 chr7:100836074-100836154 1.0000 80 chr1:173990889-173990969 1.0000 80 chr18:9334971-9335051 1.0000 80 chr17:73400462-73400542 1.0000 80 chr7:2442736-2442816 1.0000 80 chr2:63277529-63277609 1.0000 80 chr12:116714517-11671459 1.0000 80 chr16:27121332-27121412 1.0000 80 chr15:59062971-59063051 1.0000 80 chr19:3036546-3036626 1.0000 80 chr6:35655801-35655881 1.0000 80 chr14:19614559-19614639 1.0000 80 chr7:5526443-5526523 1.0000 80 chr10:60144791-60144871 1.0000 80 chr1:85667161-85667241 1.0000 80 chr16:9184182-9184262 1.0000 80 chr19:13958700-13958780 1.0000 80 chr2:202298451-202298531 1.0000 80 chr19:5322225-5322305 1.0000 80 chr1:55681219-55681299 1.0000 80 chr3:72495899-72495979 1.0000 80 chr1:213224697-213224777 1.0000 80 chr1:235491206-235491286 1.0000 80 chr19:4007290-4007370 1.0000 80 chr7:32982416-32982496 1.0000 80 chr17:37793562-37793642 1.0000 80 chr16:1701752-1701832 1.0000 80 chr4:56412037-56412117 1.0000 80 chr6:17601032-17601112 1.0000 80 chr5:56470025-56470105 1.0000 80 chr17:80231406-80231486 1.0000 80 chr12:46123662-46123742 1.0000 80 chr16:3451378-3451458 1.0000 80 chr6:26234937-26235017 1.0000 80 chr13:29107070-29107150 1.0000 80 chr1:19717557-19717637 1.0000 80 chr19:54605743-54605823 1.0000 80 chr7:121078667-121078747 1.0000 80 chr10:104180884-10418096 1.0000 80 chr10:95462395-95462475 1.0000 80 chr3:132379018-132379098 1.0000 80 chr5:10307730-10307810 1.0000 80 chr16:2389995-2390075 1.0000 80 chr1:67518987-67519067 1.0000 80 chr19:4555917-4555997 1.0000 80 chr12:80328592-80328672 1.0000 80 chr19:10535362-10535442 1.0000 80 chr8:30515306-30515386 1.0000 80 chr17:48229490-48229570 1.0000 80 chr14:24835896-24835976 1.0000 80 chr7:44121893-44121973 1.0000 80 chr19:18155946-18156026 1.0000 80 chr3:150126273-150126353 1.0000 80 chr13:41345339-41345419 1.0000 80 chr1:1655850-1655930 1.0000 80 chr1:6673032-6673112 1.0000 80 chr18:67873105-67873185 1.0000 80 chr1:228555976-228556056 1.0000 80 chr2:201936606-201936686 1.0000 80 chr5:159615649-159615729 1.0000 80 chr1:20208942-20209022 1.0000 80 chr11:14379825-14379905 1.0000 80 chr19:12780316-12780396 1.0000 80 chrX:122899070-122899150 1.0000 80 chr1:1590529-1590609 1.0000 80 chr9:115141955-115142035 1.0000 80 chr19:17858736-17858816 1.0000 80 chr3:24563161-24563241 1.0000 80 chr9:123477175-123477255 1.0000 80 chr15:68156069-68156149 1.0000 80 chr6:15246278-15246358 1.0000 80 chr12:75723967-75724047 1.0000 80 chr1:246887985-246888065 1.0000 80 chr20:31270440-31270520 1.0000 80 chr12:58258986-58259066 1.0000 80 chr20:48895765-48895845 1.0000 80 chr15:55611212-55611292 1.0000 80 chr1:61519614-61519694 1.0000 80 chr3:17783806-17783886 1.0000 80 chr18:32924600-32924680 1.0000 80 chr7:5590183-5590263 1.0000 80 chr2:243153844-243153924 1.0000 80 ******************************************************************************** ******************************************************************************** COMMAND LINE SUMMARY ******************************************************************************** This information can also be useful in the event you wish to report a problem with the MEME software. command: meme -oc ../result/final_prediction/K562/inference_raw/MEME/RankLinear0.6_40_RLF/ -dna -nmotifs 5 -w 8 -maxsize 250000 -nostatus ../result/final_prediction/K562/fasta/RankLinear0.6_40/RLF.fasta model: mod= zoops nmotifs= 5 evt= inf objective function: em= E-value of product of p-values starts= E-value of product of p-values strands: + width: minw= 8 maxw= 8 nsites: minsites= 2 maxsites= 250 wnsites= 0.8 theta: spmap= uni spfuzz= 0.5 em: prior= dirichlet b= 0.01 maxiter= 50 distance= 1e-05 trim: wg= 11 ws= 1 endgaps= yes data: n= 20000 N= 250 sample: seed= 0 hsfrac= 0 searchsize= 20000 norand= no csites= 1000 Letter frequencies in dataset: A 0.17 C 0.331 G 0.328 T 0.172 Background letter frequencies (from file dataset with add-one prior applied): A 0.17 C 0.331 G 0.328 T 0.172 Background model order: 0 ******************************************************************************** ******************************************************************************** MOTIF RSAAAAAR MEME-1 width = 8 sites = 26 llr = 240 E-value = 5.0e-006 ******************************************************************************** -------------------------------------------------------------------------------- Motif RSAAAAAR MEME-1 Description -------------------------------------------------------------------------------- Simplified A 3:a8a986 pos.-specific C :4:::1:: probability G 66::::23 matrix T 1::2:::: bits 2.6 * * 2.3 * * 2.0 * ** 1.8 ***** Relative 1.5 ***** Entropy 1.3 ***** (13.3 bits) 1.0 ****** 0.8 ******** 0.5 ******** 0.3 ******** 0.0 -------- Multilevel GGAAAAAA consensus AC G sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif RSAAAAAR MEME-1 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr18:67873105-67873185 34 3.94e-06 AGAAGCGGAG GGAAAAAA AAAAGCAACA chr12:116714517-11671459 3 3.94e-06 GG GGAAAAAA AGGGGGGAAA chr19:9879072-9879152 31 3.94e-06 CGGTGGTTGG AGAAAAAA ACACGTCTCC chr10:114206759-11420683 47 3.94e-06 CACGAAGGGG GGAAAAAA CGCTTCTAAT chr19:7716989-7717069 5 3.94e-06 AAAA AGAAAAAA AAACATTTAA chr8:21999575-21999655 28 7.92e-06 GGAAGCTGTA ACAAAAAA GCAGGGGGAG chr3:152878708-152878788 50 7.92e-06 CCCACTCCCT GCAAAAAA ACTTGGCAAC chr7:64974272-64974352 58 7.92e-06 GGGAGCTGGG GCAAAAAA CCACAAAAAG chr17:73400462-73400542 46 1.55e-05 CTCTTCCCGA GGAAAAAG ACGGAATCTT chr20:31270440-31270520 19 2.09e-05 CTTATCTGGG AGATAAAA TGCAGGCTGC chr16:33040174-33040254 18 2.86e-05 GCAAAAAGCC GCAAAAAG CCGGGGCGGC chr7:64974768-64974848 68 2.86e-05 CGCGGTGGGG GCAAAAAG CAGTG chr2:132796274-132796354 63 2.86e-05 ggcggcggag gcaaaaag ccgcggcggc chr1:1590529-1590609 49 3.40e-05 GGATGATGAC GCATAAAA CAGCGCTTGC chr1:1655850-1655930 29 3.40e-05 GGATGATGAC GCATAAAA CAGCGCTTGC chr13:29107070-29107150 54 4.16e-05 GCCCCTCGCA GGAAAAGA TAAATAACAT chr9:33677270-33677350 14 4.16e-05 CTGCACAGTT AGAAAAGA CGAAGAAGAA chr16:27121332-27121412 69 5.19e-05 CCCTACTCTC TGAAAAAG GATA chr1:45750685-45750765 18 5.19e-05 aggcttgagt agataaag cggccaggaa chr16:85361990-85362070 15 5.19e-05 CGGCTGAGCC AGATAAAG GCACAGCGGG chr19:3036546-3036626 72 6.36e-05 TGTGCCCCCC GGAAAAAT C chr1:27929842-27929922 2 6.36e-05 C ACAAAAGA GCCTGGCCGG chr10:95462395-95462475 37 8.30e-05 AACAGCTCCG GGAAACAA GGGCAGCGGG chr19:2282030-2282110 7 8.30e-05 CCAACC TCAAAAAG TGGCCGCTTC chr16:33619142-33619222 17 8.30e-05 GATGCGCTCA GGAAACAA GGAGGCGCTC chrX:71792815-71792895 22 1.03e-04 CACAGTTCAA GGAAAAGG GTTTGGCAGA -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif RSAAAAAR MEME-1 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr18:67873105-67873185 3.9e-06 33_[+1]_39 chr12:116714517-11671459 3.9e-06 2_[+1]_70 chr19:9879072-9879152 3.9e-06 30_[+1]_42 chr10:114206759-11420683 3.9e-06 46_[+1]_26 chr19:7716989-7717069 3.9e-06 4_[+1]_68 chr8:21999575-21999655 7.9e-06 27_[+1]_45 chr3:152878708-152878788 7.9e-06 49_[+1]_23 chr7:64974272-64974352 7.9e-06 57_[+1]_15 chr17:73400462-73400542 1.6e-05 45_[+1]_27 chr20:31270440-31270520 2.1e-05 18_[+1]_54 chr16:33040174-33040254 2.9e-05 17_[+1]_55 chr7:64974768-64974848 2.9e-05 67_[+1]_5 chr2:132796274-132796354 2.9e-05 62_[+1]_10 chr1:1590529-1590609 3.4e-05 48_[+1]_24 chr1:1655850-1655930 3.4e-05 28_[+1]_44 chr13:29107070-29107150 4.2e-05 53_[+1]_19 chr9:33677270-33677350 4.2e-05 13_[+1]_59 chr16:27121332-27121412 5.2e-05 68_[+1]_4 chr1:45750685-45750765 5.2e-05 17_[+1]_55 chr16:85361990-85362070 5.2e-05 14_[+1]_58 chr19:3036546-3036626 6.4e-05 71_[+1]_1 chr1:27929842-27929922 6.4e-05 1_[+1]_71 chr10:95462395-95462475 8.3e-05 36_[+1]_36 chr19:2282030-2282110 8.3e-05 6_[+1]_66 chr16:33619142-33619222 8.3e-05 16_[+1]_56 chrX:71792815-71792895 0.0001 21_[+1]_51 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif RSAAAAAR MEME-1 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF RSAAAAAR width=8 seqs=26 chr18:67873105-67873185 ( 34) GGAAAAAA 1 chr12:116714517-11671459 ( 3) GGAAAAAA 1 chr19:9879072-9879152 ( 31) AGAAAAAA 1 chr10:114206759-11420683 ( 47) GGAAAAAA 1 chr19:7716989-7717069 ( 5) AGAAAAAA 1 chr8:21999575-21999655 ( 28) ACAAAAAA 1 chr3:152878708-152878788 ( 50) GCAAAAAA 1 chr7:64974272-64974352 ( 58) GCAAAAAA 1 chr17:73400462-73400542 ( 46) GGAAAAAG 1 chr20:31270440-31270520 ( 19) AGATAAAA 1 chr16:33040174-33040254 ( 18) GCAAAAAG 1 chr7:64974768-64974848 ( 68) GCAAAAAG 1 chr2:132796274-132796354 ( 63) GCAAAAAG 1 chr1:1590529-1590609 ( 49) GCATAAAA 1 chr1:1655850-1655930 ( 29) GCATAAAA 1 chr13:29107070-29107150 ( 54) GGAAAAGA 1 chr9:33677270-33677350 ( 14) AGAAAAGA 1 chr16:27121332-27121412 ( 69) TGAAAAAG 1 chr1:45750685-45750765 ( 18) AGATAAAG 1 chr16:85361990-85362070 ( 15) AGATAAAG 1 chr19:3036546-3036626 ( 72) GGAAAAAT 1 chr1:27929842-27929922 ( 2) ACAAAAGA 1 chr10:95462395-95462475 ( 37) GGAAACAA 1 chr19:2282030-2282110 ( 7) TCAAAAAG 1 chr16:33619142-33619222 ( 17) GGAAACAA 1 chrX:71792815-71792895 ( 22) GGAAAAGG 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif RSAAAAAR MEME-1 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 11.0846 E= 5.0e-006 86 -1134 91 -116 -1134 22 91 -1134 256 -1134 -1134 -1134 225 -1134 -1134 16 256 -1134 -1134 -1134 244 -210 -1134 -1134 232 -1134 -109 -1134 186 -1134 8 -216 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif RSAAAAAR MEME-1 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 26 E= 5.0e-006 0.307692 0.000000 0.615385 0.076923 0.000000 0.384615 0.615385 0.000000 1.000000 0.000000 0.000000 0.000000 0.807692 0.000000 0.000000 0.192308 1.000000 0.000000 0.000000 0.000000 0.923077 0.076923 0.000000 0.000000 0.846154 0.000000 0.153846 0.000000 0.615385 0.000000 0.346154 0.038462 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif RSAAAAAR MEME-1 regular expression -------------------------------------------------------------------------------- [GA][GC]AAAAA[AG] -------------------------------------------------------------------------------- Time 4.95 secs. ******************************************************************************** ******************************************************************************** MOTIF YTYYTSCY MEME-2 width = 8 sites = 76 llr = 534 E-value = 4.8e-004 ******************************************************************************** -------------------------------------------------------------------------------- Motif YTYYTSCY MEME-2 Description -------------------------------------------------------------------------------- Simplified A :::::::2 pos.-specific C 6:56:586 probability G :::::4:: matrix T 4a54a133 bits 2.6 * * 2.3 * * 2.0 * * 1.8 * * Relative 1.5 * * Entropy 1.3 * * (10.1 bits) 1.0 ***** * 0.8 ***** * 0.5 ***** ** 0.3 ******** 0.0 -------- Multilevel CTTCTCCC consensus T CT GTT sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YTYYTSCY MEME-2 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr19:18155946-18156026 53 8.30e-06 GCTGTCGCTG TTTTTCCT CCCTGTGAGA chr7:32767643-32767723 3 8.30e-06 CG TTTTTCCT CTTTCTCCGT chr7:103630442-103630522 31 8.30e-06 GTGTGCCCTG TTTTTCCT GGGAGGATGC chr16:32127586-32127666 42 8.30e-06 TGCCGCGGCT TTTTTCCC GACCAGGCTT chr1:246887985-246888065 1 3.25e-05 . TTTCTCCC GCAGGGATGC chr16:27121332-27121412 35 3.25e-05 CTCCCGTAGC TTTCTCCC GAAAACGTTT chr15:96874168-96874248 58 3.25e-05 TCTTTTATCA TTTCTCCC CCGCCGCCGG chr2:91670338-91670418 45 3.25e-05 CCACCGCGGC TTTTTGCC CGCTGCGGGT chr1:121138663-121138743 22 3.25e-05 ccgccgcggc tttttgct gccgcgactt chr1:121138464-121138544 24 3.25e-05 CCGCCGTGGC TTTTTGCC CGCCGCAGCT chr7:64601230-64601310 70 3.25e-05 CCGCCGCGGC TTTTTGCC CCC chr7:65112472-65112552 47 3.25e-05 CCGCCGCGGC TTTTTGCC CCCGTCGCCG chr3:195475042-195475122 48 4.84e-05 ACTGCAGGTT CTTTTCCC ACAAGGAGAC chr1:23895029-23895109 43 4.84e-05 GCGCCCCCTG CTTTTCCT CCCCTAGTCA chr3:170626229-170626309 70 4.84e-05 TCCCCACCAG CTTTTCCC CAC chr1:19717557-19717637 15 6.86e-05 ACACTTTTTT TTTTTCTT AAATCATCCA chr10:73078802-73078882 36 6.86e-05 GGTGACTCAC TTTTTCTC CTATAAAATG chr19:35455058-35455138 32 6.86e-05 GGATCGCGAG TTTCTGCC CAGCCTCTCG chr5:159615649-159615729 11 1.18e-04 CTTTGGCCGG CTTCTCCC TGCGGAGAAG chr19:54605743-54605823 18 1.18e-04 agtcattcac cttctccc gggctcagtt chr6:34359706-34359786 38 1.18e-04 AGCCCACTGC CTTCTCCC GCGGCCGCTC chr19:14168202-14168282 36 1.18e-04 GCAGCCGCCG CTTCTCCT GCGCACAGAG chr3:132379018-132379098 1 1.30e-04 . TTTCTCTT AGATACCCGG chr6:15246278-15246358 32 1.98e-04 GGAGTTGACT CTTCTGCT CGCACTGCTG chr1:67518987-67519067 8 1.98e-04 CAACCAA CTTCTGCC TCTGGGTCCC chr5:149109884-149109964 70 1.98e-04 GCTCTCCTCC TTCTTCCT CAA chr7:106656902-106656982 18 1.98e-04 ATTCTTCTGG TTCTTCCC ACACacttgg chr19:14142722-14142802 38 2.11e-04 GTTGTGGGTG CTTTTCCA GCGGACGCGT chr13:41345339-41345419 29 2.97e-04 GCCTGGCGCC TTCCTCCC CCTTTGCGCT chr11:67275347-67275427 67 2.97e-04 ctCAGGCCGT CTTCTCTT CGAGAC chr1:28696534-28696614 73 2.97e-04 TGGCTGGGCC CTTTTGTC chr2:43451419-43451499 13 2.97e-04 CCGCCTTCCC TTCCTCCT CACTGGCGCC chr7:112726700-112726780 62 2.97e-04 CAGCATTAAG CTTTTGTC CCTTCGTGGC chr6:84743887-84743967 15 2.97e-04 TTGGGTGGGC TTCCTCCC CTCCGCTGGG chr1:117909227-117909307 69 2.97e-04 GATCGGCGAC CTTCTCTT CTTT chr1:55681219-55681299 27 3.52e-04 GCGAGGAAGG CTTCTCCA TCGTCGCCAC chr17:73400462-73400542 36 3.52e-04 GAAAGAGAGT CTCTTCCC GAGGAAAAAG chr19:2282030-2282110 21 4.13e-04 AAAGTGGCCG CTTCTGTC CAGCTCCCCG chr19:633960-634040 4 4.13e-04 gcT TTTTTTTT TTTTTTTTCA chr10:97051183-97051263 2 4.13e-04 C TTTTTGTA ATCGGTAATG chr19:610878-610958 64 4.13e-04 gggaggatcc ttcctgcc tcttccggc chr19:3388830-3388910 5 4.13e-04 aCCG TTTTTTTT AAGGGGTGAT chr21:38739308-38739388 8 4.13e-04 gctgctg ttcctgct gctgctgttg chr2:243153844-243153924 30 5.38e-04 cggcagggct ctcttgct cgcagtatag chrX:122899070-122899150 6 5.38e-04 AGCCG CTTCTTcc gccgccgccg chr17:48229490-48229570 73 5.38e-04 CGGcctctgc ctcctccc chr1:235491206-235491286 17 5.38e-04 GCTCCGGCTC CTCCTCCT CCCGCGGCGG chr2:63277529-63277609 67 5.38e-04 AGCACCTCGC CTCCTCCC TGCCAC chr17:62915814-62915894 38 5.38e-04 CCGGCCGGAC CTCCTCCC TGCGTCTCCC chr2:30934647-30934727 69 5.38e-04 AGAGGACGAG CTCCTCCT CTTG chr17:40706645-40706725 24 5.38e-04 GGCCACAGCT CTCCTCCC GCCGCCGCAG chr11:190029-190109 65 5.38e-04 ctgcatggtc ctcttgct catggtgt chr16:86609640-86609720 55 5.38e-04 ACTTTGCACA CTTCTGCA AACGCGCGGG chr16:85202388-85202468 37 5.38e-04 CCTTACCTGG CTCCTCCC GCGTCCTGAT chr2:114361704-114361784 48 5.38e-04 ctacagggcc ctcttgct tacagtgctg chr12:118810498-11881057 2 5.70e-04 c TTCCTCTC CCACACTTGT chr20:31270440-31270520 38 6.84e-04 GCAGGCTGCT CTCCTGCT GAAGATGTTA chr1:20208942-20209022 34 6.84e-04 GCGCCTTTCC CTCCTGCC GCTGGGGACT chr17:42402493-42402573 53 6.84e-04 tcaagcgatc ctcctgcc tcagcctccg chr6:138725119-138725199 12 6.84e-04 CAGCCGCCAC CTCCTGCC TTTCTCTGCC chr19:5322225-5322305 57 7.13e-04 GGTGGCTGGG CTTTTTCA GGCTTAAAAG chr6:32223190-32223270 8 8.03e-04 GGTAGGT TTCCTTCC TCCGCCTGCC chr22:25201894-25201974 68 8.03e-04 GACGGACGCT TTCCTTCC CCGCC chr17:81153469-81153549 6 8.03e-04 GGCAT CTCCTCTC CTGCAGCGCC chr14:106765289-10676536 9 8.03e-04 AGTACCCC CTCTTGTC CTGAGTGTCC chr16:3314064-3314144 25 8.54e-04 GCACAGCCGT CTCCTCCA GGACCCCTCC chr1:227505934-227506014 6 8.54e-04 TCCCC CTTCTTCA CACCCCTGGG chr16:67597155-67597235 11 8.54e-04 CGGGCTGCCC CTCCTCCA GCCAGCCCCG chr19:1676022-1676102 8 8.99e-04 GCGCCGC TTCTTGTA AACGGTTCCC chr19:48113509-48113589 17 8.99e-04 GCTTCCCCGA CTCCTGTC ACGGGCGGCC chrX:10087674-10087754 7 8.99e-04 GATGAA TTCTTGTA TGGCACTGCC chr14:106873621-10687370 9 8.99e-04 AGTGCGCC CTCCTGTC TTGAGAGACC chr3:15247968-15248048 1 9.59e-04 . CTCCTTCC CTGCCCCGGC chr1:108742601-108742681 22 9.59e-04 TCCTGAGCCC CTCCTGCA GCTCGCCGAT chr6:111580791-111580871 5 9.59e-04 GCGG CTCCTGCA GGCGGAGGCC chr1:22109213-22109293 28 9.72e-04 GGCTGCCGTC TTCCTTTC CCCTACCCCG -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YTYYTSCY MEME-2 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr19:18155946-18156026 8.3e-06 52_[+2]_20 chr7:32767643-32767723 8.3e-06 2_[+2]_70 chr7:103630442-103630522 8.3e-06 30_[+2]_42 chr16:32127586-32127666 8.3e-06 41_[+2]_31 chr1:246887985-246888065 3.2e-05 [+2]_72 chr16:27121332-27121412 3.2e-05 34_[+2]_38 chr15:96874168-96874248 3.2e-05 57_[+2]_15 chr2:91670338-91670418 3.2e-05 44_[+2]_28 chr1:121138663-121138743 3.2e-05 21_[+2]_51 chr1:121138464-121138544 3.2e-05 23_[+2]_49 chr7:64601230-64601310 3.2e-05 69_[+2]_3 chr7:65112472-65112552 3.2e-05 46_[+2]_26 chr3:195475042-195475122 4.8e-05 47_[+2]_25 chr1:23895029-23895109 4.8e-05 42_[+2]_30 chr3:170626229-170626309 4.8e-05 69_[+2]_3 chr1:19717557-19717637 6.9e-05 14_[+2]_58 chr10:73078802-73078882 6.9e-05 35_[+2]_37 chr19:35455058-35455138 6.9e-05 31_[+2]_41 chr5:159615649-159615729 0.00012 10_[+2]_62 chr19:54605743-54605823 0.00012 17_[+2]_55 chr6:34359706-34359786 0.00012 37_[+2]_35 chr19:14168202-14168282 0.00012 35_[+2]_37 chr3:132379018-132379098 0.00013 [+2]_72 chr6:15246278-15246358 0.0002 31_[+2]_41 chr1:67518987-67519067 0.0002 7_[+2]_65 chr5:149109884-149109964 0.0002 69_[+2]_3 chr7:106656902-106656982 0.0002 17_[+2]_55 chr19:14142722-14142802 0.00021 37_[+2]_35 chr13:41345339-41345419 0.0003 28_[+2]_44 chr11:67275347-67275427 0.0003 66_[+2]_6 chr1:28696534-28696614 0.0003 72_[+2] chr2:43451419-43451499 0.0003 12_[+2]_60 chr7:112726700-112726780 0.0003 61_[+2]_11 chr6:84743887-84743967 0.0003 14_[+2]_58 chr1:117909227-117909307 0.0003 68_[+2]_4 chr1:55681219-55681299 0.00035 26_[+2]_46 chr17:73400462-73400542 0.00035 35_[+2]_37 chr19:2282030-2282110 0.00041 20_[+2]_52 chr19:633960-634040 0.00041 3_[+2]_69 chr10:97051183-97051263 0.00041 1_[+2]_71 chr19:610878-610958 0.00041 63_[+2]_9 chr19:3388830-3388910 0.00041 4_[+2]_68 chr21:38739308-38739388 0.00041 7_[+2]_65 chr2:243153844-243153924 0.00054 29_[+2]_43 chrX:122899070-122899150 0.00054 5_[+2]_67 chr17:48229490-48229570 0.00054 72_[+2] chr1:235491206-235491286 0.00054 16_[+2]_56 chr2:63277529-63277609 0.00054 66_[+2]_6 chr17:62915814-62915894 0.00054 37_[+2]_35 chr2:30934647-30934727 0.00054 68_[+2]_4 chr17:40706645-40706725 0.00054 23_[+2]_49 chr11:190029-190109 0.00054 64_[+2]_8 chr16:86609640-86609720 0.00054 54_[+2]_18 chr16:85202388-85202468 0.00054 36_[+2]_36 chr2:114361704-114361784 0.00054 47_[+2]_25 chr12:118810498-11881057 0.00057 1_[+2]_71 chr20:31270440-31270520 0.00068 37_[+2]_35 chr1:20208942-20209022 0.00068 33_[+2]_39 chr17:42402493-42402573 0.00068 52_[+2]_20 chr6:138725119-138725199 0.00068 11_[+2]_61 chr19:5322225-5322305 0.00071 56_[+2]_16 chr6:32223190-32223270 0.0008 7_[+2]_65 chr22:25201894-25201974 0.0008 67_[+2]_5 chr17:81153469-81153549 0.0008 5_[+2]_67 chr14:106765289-10676536 0.0008 8_[+2]_64 chr16:3314064-3314144 0.00085 24_[+2]_48 chr1:227505934-227506014 0.00085 5_[+2]_67 chr16:67597155-67597235 0.00085 10_[+2]_62 chr19:1676022-1676102 0.0009 7_[+2]_65 chr19:48113509-48113589 0.0009 16_[+2]_56 chrX:10087674-10087754 0.0009 6_[+2]_66 chr14:106873621-10687370 0.0009 8_[+2]_64 chr3:15247968-15248048 0.00096 [+2]_72 chr1:108742601-108742681 0.00096 21_[+2]_51 chr6:111580791-111580871 0.00096 4_[+2]_68 chr1:22109213-22109293 0.00097 27_[+2]_45 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YTYYTSCY MEME-2 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF YTYYTSCY width=8 seqs=76 chr19:18155946-18156026 ( 53) TTTTTCCT 1 chr7:32767643-32767723 ( 3) TTTTTCCT 1 chr7:103630442-103630522 ( 31) TTTTTCCT 1 chr16:32127586-32127666 ( 42) TTTTTCCC 1 chr1:246887985-246888065 ( 1) TTTCTCCC 1 chr16:27121332-27121412 ( 35) TTTCTCCC 1 chr15:96874168-96874248 ( 58) TTTCTCCC 1 chr2:91670338-91670418 ( 45) TTTTTGCC 1 chr1:121138663-121138743 ( 22) TTTTTGCT 1 chr1:121138464-121138544 ( 24) TTTTTGCC 1 chr7:64601230-64601310 ( 70) TTTTTGCC 1 chr7:65112472-65112552 ( 47) TTTTTGCC 1 chr3:195475042-195475122 ( 48) CTTTTCCC 1 chr1:23895029-23895109 ( 43) CTTTTCCT 1 chr3:170626229-170626309 ( 70) CTTTTCCC 1 chr1:19717557-19717637 ( 15) TTTTTCTT 1 chr10:73078802-73078882 ( 36) TTTTTCTC 1 chr19:35455058-35455138 ( 32) TTTCTGCC 1 chr5:159615649-159615729 ( 11) CTTCTCCC 1 chr19:54605743-54605823 ( 18) CTTCTCCC 1 chr6:34359706-34359786 ( 38) CTTCTCCC 1 chr19:14168202-14168282 ( 36) CTTCTCCT 1 chr3:132379018-132379098 ( 1) TTTCTCTT 1 chr6:15246278-15246358 ( 32) CTTCTGCT 1 chr1:67518987-67519067 ( 8) CTTCTGCC 1 chr5:149109884-149109964 ( 70) TTCTTCCT 1 chr7:106656902-106656982 ( 18) TTCTTCCC 1 chr19:14142722-14142802 ( 38) CTTTTCCA 1 chr13:41345339-41345419 ( 29) TTCCTCCC 1 chr11:67275347-67275427 ( 67) CTTCTCTT 1 chr1:28696534-28696614 ( 73) CTTTTGTC 1 chr2:43451419-43451499 ( 13) TTCCTCCT 1 chr7:112726700-112726780 ( 62) CTTTTGTC 1 chr6:84743887-84743967 ( 15) TTCCTCCC 1 chr1:117909227-117909307 ( 69) CTTCTCTT 1 chr1:55681219-55681299 ( 27) CTTCTCCA 1 chr17:73400462-73400542 ( 36) CTCTTCCC 1 chr19:2282030-2282110 ( 21) CTTCTGTC 1 chr19:633960-634040 ( 4) TTTTTTTT 1 chr10:97051183-97051263 ( 2) TTTTTGTA 1 chr19:610878-610958 ( 64) TTCCTGCC 1 chr19:3388830-3388910 ( 5) TTTTTTTT 1 chr21:38739308-38739388 ( 8) TTCCTGCT 1 chr2:243153844-243153924 ( 30) CTCTTGCT 1 chrX:122899070-122899150 ( 6) CTTCTTCC 1 chr17:48229490-48229570 ( 73) CTCCTCCC 1 chr1:235491206-235491286 ( 17) CTCCTCCT 1 chr2:63277529-63277609 ( 67) CTCCTCCC 1 chr17:62915814-62915894 ( 38) CTCCTCCC 1 chr2:30934647-30934727 ( 69) CTCCTCCT 1 chr17:40706645-40706725 ( 24) CTCCTCCC 1 chr11:190029-190109 ( 65) CTCTTGCT 1 chr16:86609640-86609720 ( 55) CTTCTGCA 1 chr16:85202388-85202468 ( 37) CTCCTCCC 1 chr2:114361704-114361784 ( 48) CTCTTGCT 1 chr12:118810498-11881057 ( 2) TTCCTCTC 1 chr20:31270440-31270520 ( 38) CTCCTGCT 1 chr1:20208942-20209022 ( 34) CTCCTGCC 1 chr17:42402493-42402573 ( 53) CTCCTGCC 1 chr6:138725119-138725199 ( 12) CTCCTGCC 1 chr19:5322225-5322305 ( 57) CTTTTTCA 1 chr6:32223190-32223270 ( 8) TTCCTTCC 1 chr22:25201894-25201974 ( 68) TTCCTTCC 1 chr17:81153469-81153549 ( 6) CTCCTCTC 1 chr14:106765289-10676536 ( 9) CTCTTGTC 1 chr16:3314064-3314144 ( 25) CTCCTCCA 1 chr1:227505934-227506014 ( 6) CTTCTTCA 1 chr16:67597155-67597235 ( 11) CTCCTCCA 1 chr19:1676022-1676102 ( 8) TTCTTGTA 1 chr19:48113509-48113589 ( 17) CTCCTGTC 1 chrX:10087674-10087754 ( 7) TTCTTGTA 1 chr14:106873621-10687370 ( 9) CTCCTGTC 1 chr3:15247968-15248048 ( 1) CTCCTTCC 1 chr1:108742601-108742681 ( 22) CTCCTGCA 1 chr6:111580791-111580871 ( 5) CTCCTGCA 1 chr1:22109213-22109293 ( 28) TTCCTTTC 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YTYYTSCY MEME-2 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 9.72094 E= 4.8e-004 -1289 81 -1289 129 -1289 -1289 -1289 254 -1289 56 -1289 158 -1289 87 -1289 120 -1289 -1289 -1289 254 -1289 60 22 -54 -1289 118 -1289 54 -10 74 -1289 75 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YTYYTSCY MEME-2 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 76 E= 4.8e-004 0.000000 0.578947 0.000000 0.421053 0.000000 0.000000 0.000000 1.000000 0.000000 0.486842 0.000000 0.513158 0.000000 0.605263 0.000000 0.394737 0.000000 0.000000 0.000000 1.000000 0.000000 0.500000 0.381579 0.118421 0.000000 0.750000 0.000000 0.250000 0.157895 0.552632 0.000000 0.289474 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YTYYTSCY MEME-2 regular expression -------------------------------------------------------------------------------- [CT]T[TC][CT]T[CG][CT][CT] -------------------------------------------------------------------------------- Time 8.65 secs. ******************************************************************************** ******************************************************************************** MOTIF RRRAGRAR MEME-3 width = 8 sites = 65 llr = 469 E-value = 9.2e-002 ******************************************************************************** -------------------------------------------------------------------------------- Motif RRRAGRAR MEME-3 Description -------------------------------------------------------------------------------- Simplified A 353a:3a4 pos.-specific C 2::::2:: probability G 547:a5:6 matrix T :1:::::: bits 2.6 * * 2.3 * * 2.0 * * 1.8 * * Relative 1.5 ** * Entropy 1.3 ** * (10.4 bits) 1.0 *** ** 0.8 **** ** 0.5 ******** 0.3 ******** 0.0 -------- Multilevel GAGAGGAG consensus AGA A A sequence C -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif RRRAGRAR MEME-3 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr1:1655850-1655930 63 1.15e-05 CCAGGACTCC AAAAGAAA CTGCGCCGTG chr4:56412037-56412117 2 1.15e-05 G AAGAGAAA CCGAGCGCCT chr16:11391500-11391580 22 1.15e-05 CTTGACGGGA AAGAGAAA CTCAGCTGCC chr7:303693-303773 26 1.15e-05 CAGGACAGAG AAGAGGAA GCCGCAGCAG chr7:302918-302998 59 1.15e-05 CAGGACAGAG AAGAGGAA GCGGCAGCAG chr15:55611212-55611292 67 3.38e-05 CGGAAACGGC GAAAGGAA ACCGCA chr17:73400462-73400542 69 3.38e-05 ATCTTGAAAT GAGAGAAA ACGA chr17:62915814-62915894 69 3.38e-05 CCGCGGCTCG GAGAGGAA GGCA chr6:17987097-17987177 28 3.38e-05 GGCGAGGGAG GAGAGGAA CTTGGACTTG chr17:46178596-46178676 57 3.38e-05 CCAAGAGCCC GAGAGGAA TCGGTGCTGC chr1:246887985-246888065 54 5.61e-05 TGAGGACAAG AAGAGGAG AGGGAGAGAT chr3:150126273-150126353 56 9.91e-05 GCCCCTCTCT GAGAGAAG CCGCGAGGGG chr19:13958700-13958780 32 9.91e-05 CCTCAGCCGG GAGAGGAG GCCCCCTGAG chr16:27121332-27121412 14 9.91e-05 GGAAGAGAGA GAGAGGAG CTCCTCCCGT chr10:17496690-17496770 73 9.91e-05 GCGGAGAGAG GAGAGGAG chr11:33280017-33280097 19 1.21e-04 ATTGTTGGGG AGGAGAAA TGTGATCCGC chr10:95462395-95462475 52 1.64e-04 CAAGGGCAGC GGGAGAAA CGGCCCGGAA chr1:32713866-32713946 45 1.64e-04 TTGCCAGGAA GGGAGAAA CGGCGCGCGG chr19:12780316-12780396 58 2.07e-04 ACGGAGATTT AGGAGAAG CCAGAAGTCT chr5:159615649-159615729 24 2.07e-04 CTCCCTGCGG AGAAGGAG GCAGCGCCGG chr12:116714517-11671459 25 2.07e-04 GGGAAAGGGG AGGAGAAG GGGAGTGCGA chr7:8008583-8008663 30 2.07e-04 GCGAGGGCTG AGGAGAAG GCTGCGAGCG chr4:113153157-113153237 57 2.07e-04 GAGCGGGAGG AGGAGGAG GAGCGGCGGC chr1:227505934-227506014 67 2.07e-04 GGCCCGGCGC AGGAGGAG GGGTCG chr9:33677270-33677350 25 2.07e-04 GAAAAGACGA AGAAGAAG CGAGAAAcgc chr19:47750726-47750806 3 2.07e-04 ct agaaggag gcccggcaca chr7:98822052-98822132 31 2.07e-04 tgaacccagg aggaggag gttgcagtga chr19:566596-566676 56 2.07e-04 gggaaacgga aggaggag tctggttctt chr18:67873105-67873185 42 2.98e-04 AGGGAAAAAA AAAAGCAA CAAGCAGGGA chr5:56470025-56470105 50 2.98e-04 CCGAGCCCGG GGGAGGAG GGGAGTGCCC chr18:9334971-9335051 63 2.98e-04 CGCGGGGGCC GGGAGAAG CCTGGGCCCG chr7:32767643-32767723 42 2.98e-04 GGGTGGCTGG GGGAGGAG GGAAGGTGGC chr1:145209074-145209154 3 2.98e-04 GT GGGAGGAG GCGGCTGAGG chr13:114103642-11410372 72 2.98e-04 AGGCTCACCC GGAAGGAG G chr19:10025594-10025674 33 2.98e-04 GCTCTGGCTG GGGAGGAG CGCCAAGCAt chr1:27929842-27929922 47 2.98e-04 TCTGGGGCTG GGGAGGAG GCGCCACTCA chr7:103630442-103630522 54 2.98e-04 GATGCGTGAG GGAAGGAG AGGGGCGGCA chr19:35455058-35455138 71 2.98e-04 GTCCAGGGCG GGAAGGAG AG chr1:6673032-6673112 3 3.13e-04 CA GAAAGCAA ACTGAACGCA chr5:150603404-150603484 49 3.13e-04 CCTCTCCTCT GAAAGCAA ACTTCTCCGC chr2:132796274-132796354 44 3.28e-04 aaaagccgca aaaagcag cggcggcgga chr7:64974272-64974352 39 3.28e-04 GGGGGGAGCG AAAAGCAG TGGGAGCTGG chr19:17858736-17858816 7 3.79e-04 GGGATG GAGAGCAG GGGGTTGGGG chr1:20208942-20209022 72 3.79e-04 GCCATGTCCC GAAAGCAG G chr6:26234937-26235017 45 3.79e-04 TAAGCGCGGC CAGAGAAA CGCCGCTGCG chr12:46123662-46123742 52 3.79e-04 AGCAGAGGGT GAGAGCAG AACCGGGGGG chr8:21999575-21999655 62 3.79e-04 GGTCGGCACA CAAAGAAA ATCTGGACTC chr5:154062529-154062609 53 3.79e-04 GCCGTGCTGG GAGAGCAG GCGAGCAGGT chr16:85361990-85362070 56 3.79e-04 CGTTTTCCAA CAAAGGAA GCCTGCGGAG chr5:10307730-10307810 54 4.22e-04 AGGCCGAACC CAGAGGAG GCGGCGTGGC chr22:25201894-25201974 43 4.22e-04 GCCTGGCCCA CAGAGGAG GGTTCAGGAC chr19:18155946-18156026 65 4.71e-04 TTTCCTCCCT GTGAGAAA GTCCCCCA chr7:44121893-44121973 2 4.71e-04 T GTGAGGAA GGCCCGGCGG chr15:59062971-59063051 7 4.71e-04 CATCTC GTAAGAAA TGCCTTAATT chr6:84743887-84743967 65 4.71e-04 TTTCCCGCTG GTGAGAAA ACTTTCCT chr10:104180884-10418096 31 5.22e-04 CCGTCCGGAG GGGAGCAA GAGCCCGGAG chr6:35655801-35655881 9 5.22e-04 AGAAGAGC ATAAGGAG CCCTGGCACA chr7:149570512-149570592 69 5.94e-04 AGTCCTGGGA GTGAGGAG AACG chr14:19614559-19614639 34 6.93e-04 CTTGGGCCTG GGAAGCAG ATCCTGGGCG chr2:63277529-63277609 39 6.93e-04 CGCGGGAGAG CGAAGGAA CCGGTTCTCC chr3:195475042-195475122 71 6.93e-04 GAGACAGCAG GGAAGCAG CA chr1:145209834-145209914 29 6.93e-04 AGGGGCTGAG CGAAGGAA TGCCAGATTC chr6:86388906-86388986 18 7.77e-04 CGGAGGCCGC CGGAGGAG CGGGCGAGCC chr19:10527117-10527197 64 7.77e-04 CCCAACAGCT CGGAGGAG ACGCTTCCT chr22:22652176-22652256 15 8.20e-04 aaggtctgtg cagagcag aacgcagctc -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif RRRAGRAR MEME-3 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr1:1655850-1655930 1.2e-05 62_[+3]_10 chr4:56412037-56412117 1.2e-05 1_[+3]_71 chr16:11391500-11391580 1.2e-05 21_[+3]_51 chr7:303693-303773 1.2e-05 25_[+3]_47 chr7:302918-302998 1.2e-05 58_[+3]_14 chr15:55611212-55611292 3.4e-05 66_[+3]_6 chr17:73400462-73400542 3.4e-05 68_[+3]_4 chr17:62915814-62915894 3.4e-05 68_[+3]_4 chr6:17987097-17987177 3.4e-05 27_[+3]_45 chr17:46178596-46178676 3.4e-05 56_[+3]_16 chr1:246887985-246888065 5.6e-05 53_[+3]_19 chr3:150126273-150126353 9.9e-05 55_[+3]_17 chr19:13958700-13958780 9.9e-05 31_[+3]_41 chr16:27121332-27121412 9.9e-05 13_[+3]_59 chr10:17496690-17496770 9.9e-05 72_[+3] chr11:33280017-33280097 0.00012 18_[+3]_54 chr10:95462395-95462475 0.00016 51_[+3]_21 chr1:32713866-32713946 0.00016 44_[+3]_28 chr19:12780316-12780396 0.00021 57_[+3]_15 chr5:159615649-159615729 0.00021 23_[+3]_49 chr12:116714517-11671459 0.00021 24_[+3]_48 chr7:8008583-8008663 0.00021 29_[+3]_43 chr4:113153157-113153237 0.00021 56_[+3]_16 chr1:227505934-227506014 0.00021 66_[+3]_6 chr9:33677270-33677350 0.00021 24_[+3]_48 chr19:47750726-47750806 0.00021 2_[+3]_70 chr7:98822052-98822132 0.00021 30_[+3]_42 chr19:566596-566676 0.00021 55_[+3]_17 chr18:67873105-67873185 0.0003 41_[+3]_31 chr5:56470025-56470105 0.0003 49_[+3]_23 chr18:9334971-9335051 0.0003 62_[+3]_10 chr7:32767643-32767723 0.0003 41_[+3]_31 chr1:145209074-145209154 0.0003 2_[+3]_70 chr13:114103642-11410372 0.0003 71_[+3]_1 chr19:10025594-10025674 0.0003 32_[+3]_40 chr1:27929842-27929922 0.0003 46_[+3]_26 chr7:103630442-103630522 0.0003 53_[+3]_19 chr19:35455058-35455138 0.0003 70_[+3]_2 chr1:6673032-6673112 0.00031 2_[+3]_70 chr5:150603404-150603484 0.00031 48_[+3]_24 chr2:132796274-132796354 0.00033 43_[+3]_29 chr7:64974272-64974352 0.00033 38_[+3]_34 chr19:17858736-17858816 0.00038 6_[+3]_66 chr1:20208942-20209022 0.00038 71_[+3]_1 chr6:26234937-26235017 0.00038 44_[+3]_28 chr12:46123662-46123742 0.00038 51_[+3]_21 chr8:21999575-21999655 0.00038 61_[+3]_11 chr5:154062529-154062609 0.00038 52_[+3]_20 chr16:85361990-85362070 0.00038 55_[+3]_17 chr5:10307730-10307810 0.00042 53_[+3]_19 chr22:25201894-25201974 0.00042 42_[+3]_30 chr19:18155946-18156026 0.00047 64_[+3]_8 chr7:44121893-44121973 0.00047 1_[+3]_71 chr15:59062971-59063051 0.00047 6_[+3]_66 chr6:84743887-84743967 0.00047 64_[+3]_8 chr10:104180884-10418096 0.00052 30_[+3]_42 chr6:35655801-35655881 0.00052 8_[+3]_64 chr7:149570512-149570592 0.00059 68_[+3]_4 chr14:19614559-19614639 0.00069 33_[+3]_39 chr2:63277529-63277609 0.00069 38_[+3]_34 chr3:195475042-195475122 0.00069 70_[+3]_2 chr1:145209834-145209914 0.00069 28_[+3]_44 chr6:86388906-86388986 0.00078 17_[+3]_55 chr19:10527117-10527197 0.00078 63_[+3]_9 chr22:22652176-22652256 0.00082 14_[+3]_58 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif RRRAGRAR MEME-3 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF RRRAGRAR width=8 seqs=65 chr1:1655850-1655930 ( 63) AAAAGAAA 1 chr4:56412037-56412117 ( 2) AAGAGAAA 1 chr16:11391500-11391580 ( 22) AAGAGAAA 1 chr7:303693-303773 ( 26) AAGAGGAA 1 chr7:302918-302998 ( 59) AAGAGGAA 1 chr15:55611212-55611292 ( 67) GAAAGGAA 1 chr17:73400462-73400542 ( 69) GAGAGAAA 1 chr17:62915814-62915894 ( 69) GAGAGGAA 1 chr6:17987097-17987177 ( 28) GAGAGGAA 1 chr17:46178596-46178676 ( 57) GAGAGGAA 1 chr1:246887985-246888065 ( 54) AAGAGGAG 1 chr3:150126273-150126353 ( 56) GAGAGAAG 1 chr19:13958700-13958780 ( 32) GAGAGGAG 1 chr16:27121332-27121412 ( 14) GAGAGGAG 1 chr10:17496690-17496770 ( 73) GAGAGGAG 1 chr11:33280017-33280097 ( 19) AGGAGAAA 1 chr10:95462395-95462475 ( 52) GGGAGAAA 1 chr1:32713866-32713946 ( 45) GGGAGAAA 1 chr19:12780316-12780396 ( 58) AGGAGAAG 1 chr5:159615649-159615729 ( 24) AGAAGGAG 1 chr12:116714517-11671459 ( 25) AGGAGAAG 1 chr7:8008583-8008663 ( 30) AGGAGAAG 1 chr4:113153157-113153237 ( 57) AGGAGGAG 1 chr1:227505934-227506014 ( 67) AGGAGGAG 1 chr9:33677270-33677350 ( 25) AGAAGAAG 1 chr19:47750726-47750806 ( 3) AGAAGGAG 1 chr7:98822052-98822132 ( 31) AGGAGGAG 1 chr19:566596-566676 ( 56) AGGAGGAG 1 chr18:67873105-67873185 ( 42) AAAAGCAA 1 chr5:56470025-56470105 ( 50) GGGAGGAG 1 chr18:9334971-9335051 ( 63) GGGAGAAG 1 chr7:32767643-32767723 ( 42) GGGAGGAG 1 chr1:145209074-145209154 ( 3) GGGAGGAG 1 chr13:114103642-11410372 ( 72) GGAAGGAG 1 chr19:10025594-10025674 ( 33) GGGAGGAG 1 chr1:27929842-27929922 ( 47) GGGAGGAG 1 chr7:103630442-103630522 ( 54) GGAAGGAG 1 chr19:35455058-35455138 ( 71) GGAAGGAG 1 chr1:6673032-6673112 ( 3) GAAAGCAA 1 chr5:150603404-150603484 ( 49) GAAAGCAA 1 chr2:132796274-132796354 ( 44) AAAAGCAG 1 chr7:64974272-64974352 ( 39) AAAAGCAG 1 chr19:17858736-17858816 ( 7) GAGAGCAG 1 chr1:20208942-20209022 ( 72) GAAAGCAG 1 chr6:26234937-26235017 ( 45) CAGAGAAA 1 chr12:46123662-46123742 ( 52) GAGAGCAG 1 chr8:21999575-21999655 ( 62) CAAAGAAA 1 chr5:154062529-154062609 ( 53) GAGAGCAG 1 chr16:85361990-85362070 ( 56) CAAAGGAA 1 chr5:10307730-10307810 ( 54) CAGAGGAG 1 chr22:25201894-25201974 ( 43) CAGAGGAG 1 chr19:18155946-18156026 ( 65) GTGAGAAA 1 chr7:44121893-44121973 ( 2) GTGAGGAA 1 chr15:59062971-59063051 ( 7) GTAAGAAA 1 chr6:84743887-84743967 ( 65) GTGAGAAA 1 chr10:104180884-10418096 ( 31) GGGAGCAA 1 chr6:35655801-35655881 ( 9) ATAAGGAG 1 chr7:149570512-149570592 ( 69) GTGAGGAG 1 chr14:19614559-19614639 ( 34) GGAAGCAG 1 chr2:63277529-63277609 ( 39) CGAAGGAA 1 chr3:195475042-195475122 ( 71) GGAAGCAG 1 chr1:145209834-145209914 ( 29) CGAAGGAA 1 chr6:86388906-86388986 ( 18) CGGAGGAG 1 chr19:10527117-10527197 ( 64) CGGAGGAG 1 chr22:22652176-22652256 ( 15) CAGAGCAG 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif RRRAGRAR MEME-3 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 9.46427 E= 9.2e-002 93 -110 67 -1267 144 -1267 44 -89 99 -1267 101 -1267 256 -1267 -1267 -1267 -1267 -1267 161 -1267 71 -72 67 -1267 256 -1267 -1267 -1267 124 -1267 87 -1267 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif RRRAGRAR MEME-3 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 65 E= 9.2e-002 0.323077 0.153846 0.523077 0.000000 0.461538 0.000000 0.446154 0.092308 0.338462 0.000000 0.661538 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.276923 0.200000 0.523077 0.000000 1.000000 0.000000 0.000000 0.000000 0.400000 0.000000 0.600000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif RRRAGRAR MEME-3 regular expression -------------------------------------------------------------------------------- [GA][AG][GA]AG[GAC]A[GA] -------------------------------------------------------------------------------- Time 12.23 secs. ******************************************************************************** ******************************************************************************** MOTIF TDYTTAAA MEME-4 width = 8 sites = 18 llr = 170 E-value = 8.2e-001 ******************************************************************************** -------------------------------------------------------------------------------- Motif TDYTTAAA MEME-4 Description -------------------------------------------------------------------------------- Simplified A :2:1:999 pos.-specific C 2:5::1:: probability G 23:::::: matrix T 6459a:11 bits 2.6 * 2.3 * ** 2.0 ***** 1.8 ***** Relative 1.5 ***** Entropy 1.3 ***** (13.6 bits) 1.0 ****** 0.8 ******** 0.5 ******** 0.3 ******** 0.0 -------- Multilevel TTCTTAAA consensus GGT sequence A -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TDYTTAAA MEME-4 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr12:58258986-58259066 28 7.40e-07 TCTGCCGCCG TTTTTAAA CGGCCCCGAA chr5:108906321-108906401 12 2.89e-06 ATTGTGTTAA TTCTTAAA AAGATAAACC chr10:97051183-97051263 21 4.30e-06 TCGGTAATGA Tgtttaaa aggtgctttc chr16:85202388-85202468 62 5.71e-06 GATTGACCTT TACTTAAA GACCAGCTCC chr2:202298451-202298531 60 9.84e-06 TAATTCACCA TGCTTAAA GTTCTTGAAC chr19:9879072-9879152 3 1.13e-05 TG CTTTTAAA CAGAGGGGCA chr19:11650762-11650842 27 1.20e-05 GCCGGTTTGC TTTATAAA GCCGGGCTGG chr22:39541986-39542066 70 1.34e-05 TCCCCACTCC GATTTAAA GCT chr19:7716989-7717069 16 2.02e-05 GAAAAAAAAA CATTTAAA CTCAATTTCC chr6:32223190-32223270 25 2.29e-05 CTCCGCCTGC CTCTTAAA TAACGTGGTA chr1:6673032-6673112 56 2.66e-05 TGGCCCGGTG TTTTTAAT GCACGAACCC chr19:633960-634040 15 2.66e-05 TTTTTTTTTT TTTTTCAA GGCATACTCA chr1:228555976-228556056 2 4.27e-05 G GGCTTAAA GTGGAGAGGG chr19:5322225-5322305 65 4.27e-05 GGCTTTTTCA GGCTTAAA AGGGAGGT chr19:10527117-10527197 44 4.27e-05 TCGGGTTTAA GGCTTAAA AGCCCAACAG chr19:54605743-54605823 61 5.26e-05 tgggCTTTCA TACATAAA CTATAAAATG chrX:10087674-10087754 38 5.26e-05 TGGTGGCGGA TTCTTATA TGACACCGCC chr1:246887985-246888065 71 6.34e-05 GAGGGAGAGA TGTTTCAA AT -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TDYTTAAA MEME-4 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr12:58258986-58259066 7.4e-07 27_[+4]_45 chr5:108906321-108906401 2.9e-06 11_[+4]_61 chr10:97051183-97051263 4.3e-06 20_[+4]_52 chr16:85202388-85202468 5.7e-06 61_[+4]_11 chr2:202298451-202298531 9.8e-06 59_[+4]_13 chr19:9879072-9879152 1.1e-05 2_[+4]_70 chr19:11650762-11650842 1.2e-05 26_[+4]_46 chr22:39541986-39542066 1.3e-05 69_[+4]_3 chr19:7716989-7717069 2e-05 15_[+4]_57 chr6:32223190-32223270 2.3e-05 24_[+4]_48 chr1:6673032-6673112 2.7e-05 55_[+4]_17 chr19:633960-634040 2.7e-05 14_[+4]_58 chr1:228555976-228556056 4.3e-05 1_[+4]_71 chr19:5322225-5322305 4.3e-05 64_[+4]_8 chr19:10527117-10527197 4.3e-05 43_[+4]_29 chr19:54605743-54605823 5.3e-05 60_[+4]_12 chrX:10087674-10087754 5.3e-05 37_[+4]_35 chr1:246887985-246888065 6.3e-05 70_[+4]_2 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TDYTTAAA MEME-4 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF TDYTTAAA width=8 seqs=18 chr12:58258986-58259066 ( 28) TTTTTAAA 1 chr5:108906321-108906401 ( 12) TTCTTAAA 1 chr10:97051183-97051263 ( 21) TGTTTAAA 1 chr16:85202388-85202468 ( 62) TACTTAAA 1 chr2:202298451-202298531 ( 60) TGCTTAAA 1 chr19:9879072-9879152 ( 3) CTTTTAAA 1 chr19:11650762-11650842 ( 27) TTTATAAA 1 chr22:39541986-39542066 ( 70) GATTTAAA 1 chr19:7716989-7717069 ( 16) CATTTAAA 1 chr6:32223190-32223270 ( 25) CTCTTAAA 1 chr1:6673032-6673112 ( 56) TTTTTAAT 1 chr19:633960-634040 ( 15) TTTTTCAA 1 chr1:228555976-228556056 ( 2) GGCTTAAA 1 chr19:5322225-5322305 ( 65) GGCTTAAA 1 chr19:10527117-10527197 ( 44) GGCTTAAA 1 chr19:54605743-54605823 ( 61) TACATAAA 1 chrX:10087674-10087754 ( 38) TTCTTATA 1 chr1:246887985-246888065 ( 71) TGTTTCAA 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TDYTTAAA MEME-4 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 10.8329 E= 8.2e-001 -1081 -99 -56 183 39 -1081 2 137 -1081 60 -1081 154 -61 -1081 -1081 237 -1081 -1081 -1081 254 239 -157 -1081 -1081 247 -1081 -1081 -163 247 -1081 -1081 -163 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TDYTTAAA MEME-4 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 18 E= 8.2e-001 0.000000 0.166667 0.222222 0.611111 0.222222 0.000000 0.333333 0.444444 0.000000 0.500000 0.000000 0.500000 0.111111 0.000000 0.000000 0.888889 0.000000 0.000000 0.000000 1.000000 0.888889 0.111111 0.000000 0.000000 0.944444 0.000000 0.000000 0.055556 0.944444 0.000000 0.000000 0.055556 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TDYTTAAA MEME-4 regular expression -------------------------------------------------------------------------------- [TG][TGA][CT]TTAAA -------------------------------------------------------------------------------- Time 15.73 secs. ******************************************************************************** ******************************************************************************** MOTIF WATAAAAT MEME-5 width = 8 sites = 6 llr = 69 E-value = 2.4e+003 ******************************************************************************** -------------------------------------------------------------------------------- Motif WATAAAAT MEME-5 Description -------------------------------------------------------------------------------- Simplified A 58:8a88: pos.-specific C :::::2:: probability G :2:::::: matrix T 5:a2::2a bits 2.6 * * * 2.3 * * * 2.0 * * * 1.8 ******* Relative 1.5 ******** Entropy 1.3 ******** (16.5 bits) 1.0 ******** 0.8 ******** 0.5 ******** 0.3 ******** 0.0 -------- Multilevel AATAAAAT consensus T sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif WATAAAAT MEME-5 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr19:54605743-54605823 70 1.44e-06 ATACATAAAC TATAAAAT GGG chr10:73078802-73078882 45 1.44e-06 CTTTTTCTCC TATAAAAT GGGCGCACGC chr6:32223190-32223270 66 2.88e-06 CTGAAACCTG AATTAAAT GCAATGC chrX:10087674-10087754 56 2.88e-06 TGACACCGCC AATAAATT CCTGAGTGAC chr13:29107070-29107150 64 7.11e-06 GGAAAAGATA AATAACAT CTGAGGCGC chr16:28858200-28858280 30 9.91e-06 ttttctaatc tgtaaaat gggaatagta -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif WATAAAAT MEME-5 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr19:54605743-54605823 1.4e-06 69_[+5]_3 chr10:73078802-73078882 1.4e-06 44_[+5]_28 chr6:32223190-32223270 2.9e-06 65_[+5]_7 chrX:10087674-10087754 2.9e-06 55_[+5]_17 chr13:29107070-29107150 7.1e-06 63_[+5]_9 chr16:28858200-28858280 9.9e-06 29_[+5]_43 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif WATAAAAT MEME-5 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF WATAAAAT width=8 seqs=6 chr19:54605743-54605823 ( 70) TATAAAAT 1 chr10:73078802-73078882 ( 45) TATAAAAT 1 chr6:32223190-32223270 ( 66) AATTAAAT 1 chrX:10087674-10087754 ( 56) AATAAATT 1 chr13:29107070-29107150 ( 64) AATAACAT 1 chr16:28858200-28858280 ( 30) TGTAAAAT 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif WATAAAAT MEME-5 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 12.67 E= 2.4e+003 156 -923 -923 154 229 -923 -97 -923 -923 -923 -923 254 229 -923 -923 -4 256 -923 -923 -923 229 -99 -923 -923 229 -923 -923 -4 -923 -923 -923 254 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif WATAAAAT MEME-5 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 6 E= 2.4e+003 0.500000 0.000000 0.000000 0.500000 0.833333 0.000000 0.166667 0.000000 0.000000 0.000000 0.000000 1.000000 0.833333 0.000000 0.000000 0.166667 1.000000 0.000000 0.000000 0.000000 0.833333 0.166667 0.000000 0.000000 0.833333 0.000000 0.000000 0.166667 0.000000 0.000000 0.000000 1.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif WATAAAAT MEME-5 regular expression -------------------------------------------------------------------------------- [AT]ATAAAAT -------------------------------------------------------------------------------- Time 19.12 secs. ******************************************************************************** ******************************************************************************** SUMMARY OF MOTIFS ******************************************************************************** -------------------------------------------------------------------------------- Combined block diagrams: non-overlapping sites with p-value < 0.0001 -------------------------------------------------------------------------------- SEQUENCE NAME COMBINED P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr7:65112472-65112552 1.93e-01 2_[+2(3.25e-05)]_14_[+2(3.25e-05)]_\ 14_[+2(3.25e-05)]_14_[+2(3.25e-05)]_4 chr7:64601230-64601310 2.03e-01 32_[+2(3.25e-05)]_13_[+2(3.25e-05)]_\ 8_[+2(3.25e-05)]_3 chr7:64974272-64974352 2.12e-03 13_[+1(2.86e-05)]_36_[+1(7.92e-06)]_\ 2_[+1(2.86e-05)]_5 chr1:121138464-121138544 5.33e-02 23_[+2(3.25e-05)]_9_[+2(3.25e-05)]_\ 32 chr16:32127586-32127666 8.89e-02 14_[+2(3.25e-05)]_19_[+2(8.30e-06)]_\ 8_[+2(3.25e-05)]_15 chr19:4585038-4585118 9.95e-01 80 chr19:40910015-40910095 1.00e+00 80 chr12:57853645-57853725 2.33e-02 80 chr14:106765289-10676536 5.64e-01 80 chr5:108906321-108906401 7.76e-06 11_[+4(2.89e-06)]_61 chr2:132796274-132796354 1.13e-02 8_[+1(2.86e-05)]_24_[+1(2.86e-05)]_\ 14_[+1(2.86e-05)]_10 chr7:302918-302998 4.31e-02 5_[+3(1.15e-05)]_45_[+3(1.15e-05)]_\ 14 chr6:16238537-16238617 9.15e-02 80 chr16:15743852-15743932 7.12e-01 80 chr20:1247315-1247395 9.98e-01 80 chr3:170626229-170626309 3.11e-01 69_[+2(4.84e-05)]_3 chr19:1249961-1250041 9.95e-01 80 chr14:106873621-10687370 7.44e-01 80 chr19:35455058-35455138 2.82e-02 31_[+2(6.86e-05)]_41 chr19:17403085-17403165 7.51e-01 80 chr15:22461192-22461272 9.57e-01 80 chr7:303693-303773 4.31e-02 25_[+3(1.15e-05)]_47 chr6:12013216-12013296 9.93e-01 80 chr19:14168202-14168282 1.66e-01 80 chr1:109791947-109792027 5.68e-01 80 chr17:41174283-41174363 6.04e-01 80 chr19:566596-566676 2.01e-03 80 chr17:81153469-81153549 4.16e-01 80 chr10:17496690-17496770 2.64e-01 67_[+3(9.91e-05)]_5 chr22:19157215-19157295 7.43e-01 80 chr7:106656902-106656982 1.88e-01 80 chr2:114361704-114361784 1.02e-01 80 chr12:108522901-10852298 9.98e-01 80 chr16:88905532-88905612 1.00e+00 80 chr17:47308065-47308145 3.13e-01 80 chr9:33167033-33167113 4.56e-01 80 chr5:79704186-79704266 8.84e-01 80 chr7:64974768-64974848 5.07e-03 13_[+1(2.86e-05)]_24_[+1(2.86e-05)]_\ 14_[+1(2.86e-05)]_5 chr19:39465867-39465947 9.22e-01 80 chr19:2475705-2475785 4.66e-01 80 chr19:11650762-11650842 8.89e-03 26_[+4(1.20e-05)]_46 chr1:121138663-121138743 1.99e-01 21_[+2(3.25e-05)]_8_[+2(3.25e-05)]_\ 35 chr16:85361990-85362070 1.43e-03 14_[+1(5.19e-05)]_58 chr6:138725119-138725199 7.97e-01 80 chr5:154062529-154062609 6.19e-01 80 chr10:73078802-73078882 6.00e-05 44_[+5(1.44e-06)]_28 chr16:33040174-33040254 1.39e-02 7_[+1(2.86e-05)]_2_[+1(2.86e-05)]_\ 55 chr15:96900421-96900501 9.96e-01 80 chr16:85202388-85202468 3.95e-04 61_[+4(5.71e-06)]_11 chr20:30196422-30196502 2.56e-01 80 chr12:118810498-11881057 5.35e-01 80 chr3:20081534-20081614 9.99e-01 80 chr22:25201894-25201974 2.77e-02 80 chrX:122648192-122648272 9.10e-01 80 chr7:103630442-103630522 3.47e-03 30_[+2(8.30e-06)]_42 chr1:45750685-45750765 3.03e-02 17_[+1(5.19e-05)]_55 chr17:42402493-42402573 1.91e-01 80 chr5:149109884-149109964 3.82e-02 80 chr4:2956819-2956899 9.88e-01 80 chr19:13905743-13905823 7.89e-01 80 chrX:10087674-10087754 1.31e-04 37_[+4(5.26e-05)]_10_[+5(2.88e-06)]_\ 17 chr16:86609640-86609720 1.20e-01 80 chr7:98822052-98822132 1.15e-01 80 chr1:41267903-41267983 9.43e-01 80 chr6:32223190-32223270 2.42e-05 24_[+4(2.29e-05)]_33_[+5(2.88e-06)]_\ 7 chr19:10527117-10527197 5.74e-03 43_[+4(4.27e-05)]_29 chr22:29702521-29702601 2.09e-01 80 chr6:148646-148726 6.58e-01 80 chr22:39541986-39542066 2.29e-02 69_[+4(1.34e-05)]_3 chr1:27929842-27929922 3.33e-02 1_[+1(6.36e-05)]_71 chr16:11391500-11391580 4.68e-03 21_[+3(1.15e-05)]_51 chr1:145209834-145209914 6.82e-01 80 chr11:85565806-85565886 2.42e-01 80 chr1:117909227-117909307 1.52e-01 80 chr9:132259037-132259117 9.14e-01 80 chr6:111580791-111580871 4.80e-01 80 chr12:32112197-32112277 6.54e-01 80 chr2:91670338-91670418 1.32e-01 20_[+2(3.25e-05)]_16_[+2(3.25e-05)]_\ 28 chr20:45317804-45317884 6.37e-01 80 chr6:84743887-84743967 8.19e-03 80 chr5:150603404-150603484 1.65e-02 80 chr3:152878708-152878788 4.64e-04 49_[+1(7.92e-06)]_23 chr21:38739308-38739388 3.84e-01 80 chr3:196366878-196366958 3.48e-01 80 chr16:33619142-33619222 1.27e-01 16_[+1(8.30e-05)]_56 chr19:7716989-7717069 6.32e-08 4_[+1(3.94e-06)]_3_[+4(2.02e-05)]_\ 57 chr1:211752338-211752418 7.12e-01 80 chr1:12079712-12079792 6.42e-02 54_[+5(5.30e-05)]_18 chr5:61602446-61602526 5.99e-01 80 chr16:68119445-68119525 2.77e-01 80 chr1:90099099-90099179 9.91e-01 80 chr19:47750726-47750806 2.01e-03 80 chr15:22462158-22462238 1.00e+00 80 chr3:10206731-10206811 9.77e-01 80 chr19:10025594-10025674 4.68e-01 80 chr3:138663915-138663995 7.33e-01 80 chr16:67597155-67597235 7.25e-01 80 chr1:185015056-185015136 9.71e-01 80 chr1:32713866-32713946 8.45e-02 80 chr19:48113509-48113589 2.34e-01 80 chr2:179278380-179278460 4.31e-01 80 chr6:34359706-34359786 9.72e-02 80 chr10:51572501-51572581 9.57e-01 80 chr4:123843662-123843742 9.28e-01 80 chr11:190029-190109 3.83e-01 80 chr15:40615662-40615742 4.66e-01 80 chr16:28858200-28858280 1.32e-03 29_[+5(9.91e-06)]_43 chr6:157041082-157041162 4.75e-02 80 chr15:96874168-96874248 3.87e-03 57_[+2(3.25e-05)]_15 chr9:132199410-132199490 2.62e-01 80 chr6:86388906-86388986 2.90e-01 80 chr19:18229036-18229116 6.39e-02 80 chr5:177557655-177557735 8.59e-01 80 chrX:19003048-19003128 9.93e-01 80 chr8:21999575-21999655 1.14e-04 27_[+1(7.92e-06)]_28_[+5(8.29e-05)]_\ 9 chr7:112726700-112726780 1.24e-02 80 chr17:4901025-4901105 5.78e-01 80 chr17:40706645-40706725 5.36e-01 80 chr19:14142722-14142802 1.99e-01 80 chr7:149570512-149570592 2.93e-01 80 chr2:30934647-30934727 4.34e-02 80 chr3:197476353-197476433 6.66e-01 80 chr9:33677270-33677350 1.81e-03 13_[+1(4.16e-05)]_59 chr5:180258148-180258228 7.04e-01 80 chr19:3388830-3388910 4.72e-02 80 chr22:22652176-22652256 6.50e-01 80 chr19:610878-610958 6.86e-02 80 chr6:33247909-33247989 7.06e-01 80 chr17:46178596-46178676 8.68e-02 56_[+3(3.38e-05)]_16 chrX:71792815-71792895 4.59e-03 80 chr1:227505934-227506014 2.41e-02 80 chr4:90032809-90032889 1.00e+00 80 chr11:64795035-64795115 4.88e-01 80 chr11:33280017-33280097 1.32e-01 80 chr6:17987097-17987177 1.61e-03 27_[+3(3.38e-05)]_45 chr19:1512820-1512900 3.81e-01 80 chr1:22109213-22109293 6.76e-02 80 chr7:73081816-73081896 2.46e-02 80 chr1:150521383-150521463 9.91e-01 80 chr16:3314064-3314144 5.68e-01 80 chr2:43451419-43451499 2.15e-01 80 chr4:113153157-113153237 2.24e-01 80 chr1:23895029-23895109 2.48e-02 42_[+2(4.84e-05)]_30 chr19:47017015-47017095 6.96e-01 80 chr7:138793942-138794022 8.16e-01 80 chr10:97051183-97051263 1.97e-04 20_[+4(4.30e-06)]_52 chr1:28696534-28696614 4.57e-01 80 chr7:2599068-2599148 9.62e-01 80 chr11:67275347-67275427 8.93e-02 80 chr3:20082230-20082310 2.01e-01 80 chr10:114206759-11420683 1.35e-03 46_[+1(3.94e-06)]_26 chr11:17375105-17375185 9.97e-01 80 chr13:114103642-11410372 4.83e-01 80 chr7:8008583-8008663 2.58e-01 80 chr7:148787588-148787668 9.82e-01 80 chr19:9879072-9879152 1.25e-05 2_[+4(1.13e-05)]_20_[+1(3.94e-06)]_\ 42 chr1:108742601-108742681 8.49e-01 80 chr1:145209074-145209154 1.42e-01 80 chr11:86666170-86666250 8.57e-01 80 chr17:62915814-62915894 3.60e-02 68_[+3(3.38e-05)]_4 chr19:1676022-1676102 6.80e-02 80 chr12:125230699-12523077 7.94e-01 80 chr6:4647937-4648017 5.59e-01 80 chr3:195475042-195475122 1.73e-02 47_[+2(4.84e-05)]_25 chr19:633960-634040 5.15e-03 14_[+4(2.66e-05)]_58 chr3:15247968-15248048 7.82e-01 80 chr19:2282030-2282110 1.53e-02 6_[+1(8.30e-05)]_66 chr7:32767643-32767723 1.52e-03 2_[+2(8.30e-06)]_70 chr7:100836074-100836154 8.96e-01 80 chr1:173990889-173990969 7.07e-01 80 chr18:9334971-9335051 5.75e-01 80 chr17:73400462-73400542 4.29e-05 45_[+1(1.55e-05)]_15_[+3(3.38e-05)]_\ 4 chr7:2442736-2442816 3.18e-01 80 chr2:63277529-63277609 1.48e-01 80 chr12:116714517-11671459 4.05e-04 2_[+1(3.94e-06)]_70 chr16:27121332-27121412 1.52e-05 13_[+3(9.91e-05)]_13_[+2(3.25e-05)]_\ 26_[+1(5.19e-05)]_4 chr15:59062971-59063051 1.35e-02 80 chr19:3036546-3036626 9.98e-02 71_[+1(6.36e-05)]_1 chr6:35655801-35655881 4.14e-02 80 chr14:19614559-19614639 1.33e-01 80 chr7:5526443-5526523 5.72e-01 80 chr10:60144791-60144871 3.52e-01 80 chr1:85667161-85667241 1.00e+00 80 chr16:9184182-9184262 7.76e-01 80 chr19:13958700-13958780 2.86e-01 31_[+3(9.91e-05)]_41 chr2:202298451-202298531 4.94e-04 59_[+4(9.84e-06)]_13 chr19:5322225-5322305 2.26e-03 64_[+4(4.27e-05)]_8 chr1:55681219-55681299 6.47e-02 80 chr3:72495899-72495979 3.97e-01 80 chr1:213224697-213224777 4.12e-01 80 chr1:235491206-235491286 6.00e-01 80 chr19:4007290-4007370 6.01e-01 80 chr7:32982416-32982496 3.20e-01 80 chr17:37793562-37793642 9.80e-01 80 chr16:1701752-1701832 3.83e-01 80 chr4:56412037-56412117 3.13e-02 1_[+3(1.15e-05)]_71 chr6:17601032-17601112 9.92e-01 80 chr5:56470025-56470105 1.11e-01 80 chr17:80231406-80231486 9.62e-01 80 chr12:46123662-46123742 2.82e-01 80 chr16:3451378-3451458 9.92e-01 80 chr6:26234937-26235017 4.86e-02 80 chr13:29107070-29107150 2.57e-04 53_[+1(4.16e-05)]_2_[+5(7.11e-06)]_\ 9 chr1:19717557-19717637 3.75e-07 17_[+4(2.89e-06)]_55 chr19:54605743-54605823 1.90e-06 43_[+5(9.91e-06)]_9_[+4(5.26e-05)]_\ 1_[+5(1.44e-06)]_3 chr7:121078667-121078747 8.48e-01 80 chr10:104180884-10418096 6.63e-01 80 chr10:95462395-95462475 6.02e-03 36_[+1(8.30e-05)]_36 chr3:132379018-132379098 1.98e-02 80 chr5:10307730-10307810 2.00e-01 80 chr16:2389995-2390075 7.97e-01 80 chr1:67518987-67519067 3.28e-02 80 chr19:4555917-4555997 5.43e-01 80 chr12:80328592-80328672 5.29e-01 80 chr19:10535362-10535442 9.32e-01 80 chr8:30515306-30515386 1.46e-01 80 chr17:48229490-48229570 9.28e-02 80 chr14:24835896-24835976 1.00e+00 80 chr7:44121893-44121973 4.86e-01 80 chr19:18155946-18156026 5.33e-04 52_[+2(8.30e-06)]_20 chr3:150126273-150126353 2.77e-01 55_[+3(9.91e-05)]_17 chr13:41345339-41345419 3.47e-01 80 chr1:1655850-1655930 7.05e-06 28_[+1(3.40e-05)]_26_[+3(1.15e-05)]_\ 10 chr1:6673032-6673112 2.50e-03 55_[+4(2.66e-05)]_17 chr18:67873105-67873185 1.43e-03 33_[+1(3.94e-06)]_39 chr1:228555976-228556056 2.21e-02 1_[+4(4.27e-05)]_71 chr2:201936606-201936686 8.18e-01 80 chr5:159615649-159615729 1.17e-02 80 chr1:20208942-20209022 1.02e-01 80 chr11:14379825-14379905 9.99e-01 80 chr19:12780316-12780396 8.89e-02 80 chrX:122899070-122899150 3.08e-01 80 chr1:1590529-1590609 1.56e-03 48_[+1(3.40e-05)]_24 chr9:115141955-115142035 3.75e-01 80 chr19:17858736-17858816 1.13e-01 80 chr3:24563161-24563241 9.70e-01 80 chr9:123477175-123477255 9.96e-01 80 chr15:68156069-68156149 9.65e-01 80 chr6:15246278-15246358 2.65e-02 80 chr12:75723967-75724047 4.05e-01 80 chr1:246887985-246888065 4.52e-06 [+2(3.25e-05)]_45_[+3(5.61e-05)]_9_\ [+4(6.34e-05)]_2 chr20:31270440-31270520 2.92e-05 18_[+1(2.09e-05)]_24_[+5(4.47e-05)]_\ 22 chr12:58258986-58259066 3.03e-03 27_[+4(7.40e-07)]_45 chr20:48895765-48895845 2.73e-01 80 chr15:55611212-55611292 1.68e-02 66_[+3(3.38e-05)]_6 chr1:61519614-61519694 2.87e-01 80 chr3:17783806-17783886 9.85e-01 80 chr18:32924600-32924680 1.55e-01 80 chr7:5590183-5590263 3.85e-01 80 chr2:243153844-243153924 4.08e-01 80 -------------------------------------------------------------------------------- ******************************************************************************** ******************************************************************************** Stopped because requested number of motifs (5) found. ******************************************************************************** CPU: c17n10.farnam.hpc.yale.internal ********************************************************************************