******************************************************************************** MEME - Motif discovery tool ******************************************************************************** MEME version 5.3.3 (Release date: Sun Feb 7 15:39:52 2021 -0800) For further information on how to interpret these results please access https://meme-suite.org/meme. To get a copy of the MEME Suite software please access https://meme-suite.org. ******************************************************************************** ******************************************************************************** REFERENCE ******************************************************************************** If you use this program in your research, please cite: Timothy L. Bailey and Charles Elkan, "Fitting a mixture model by expectation maximization to discover motifs in biopolymers", Proceedings of the Second International Conference on Intelligent Systems for Molecular Biology, pp. 28-36, AAAI Press, Menlo Park, California, 1994. ******************************************************************************** ******************************************************************************** TRAINING SET ******************************************************************************** PRIMARY SEQUENCES= ../result/final_prediction/K562/fasta/RankLinear0.6_40/RBFOX2.fasta CONTROL SEQUENCES= --none-- ALPHABET= ACGT Sequence name Weight Length Sequence name Weight Length ------------- ------ ------ ------------- ------ ------ chr10:126107433-12610751 1.0000 80 chr2:74405871-74405951 1.0000 80 chr3:156272729-156272809 1.0000 80 chr9:80912136-80912216 1.0000 80 chr12:6579789-6579869 1.0000 80 chr8:82644632-82644712 1.0000 80 chr13:27825686-27825766 1.0000 80 chr2:234763073-234763153 1.0000 80 chr2:27255834-27255914 1.0000 80 chr10:5855234-5855314 1.0000 80 chrX:48776211-48776291 1.0000 80 chr14:20937579-20937659 1.0000 80 chr22:22863003-22863083 1.0000 80 chr2:106015366-106015446 1.0000 80 chr22:39916939-39917019 1.0000 80 chr15:44084583-44084663 1.0000 80 chr12:104324261-10432434 1.0000 80 chr5:43313448-43313528 1.0000 80 chr19:14640425-14640505 1.0000 80 chr13:21714682-21714762 1.0000 80 chr17:42143948-42144028 1.0000 80 chr5:148930796-148930876 1.0000 80 chr16:48399750-48399830 1.0000 80 chr16:74640907-74640987 1.0000 80 chr1:184943270-184943350 1.0000 80 chr10:120840198-12084027 1.0000 80 chrX:118925475-118925555 1.0000 80 chrX:16804604-16804684 1.0000 80 chrX:131157370-131157450 1.0000 80 chr8:47529088-47529168 1.0000 80 chr22:29196437-29196517 1.0000 80 chr9:3526599-3526679 1.0000 80 chr8:87520791-87520871 1.0000 80 chr6:83902908-83902988 1.0000 80 chr2:198318286-198318366 1.0000 80 chr13:96329382-96329462 1.0000 80 chr6:26033612-26033692 1.0000 80 chr11:70049468-70049548 1.0000 80 chr16:30456892-30456972 1.0000 80 chr3:169482526-169482606 1.0000 80 chr9:37485965-37486045 1.0000 80 chr6:7313215-7313295 1.0000 80 chr17:16342514-16342594 1.0000 80 chr2:113403534-113403614 1.0000 80 chrX:129116581-129116661 1.0000 80 chr2:227700616-227700696 1.0000 80 chr11:64937665-64937745 1.0000 80 chr7:56119463-56119543 1.0000 80 chr4:24586053-24586133 1.0000 80 chr11:126173818-12617389 1.0000 80 chr1:46050091-46050171 1.0000 80 chrX:24073055-24073135 1.0000 80 chr11:68039368-68039448 1.0000 80 chr5:173315363-173315443 1.0000 80 chr1:151512762-151512842 1.0000 80 chr2:201981296-201981376 1.0000 80 chrX:16737766-16737846 1.0000 80 chr22:36877560-36877640 1.0000 80 chrX:23801276-23801356 1.0000 80 chr13:31191622-31191702 1.0000 80 chr3:150264142-150264222 1.0000 80 chr12:76478330-76478410 1.0000 80 chr17:62501850-62501930 1.0000 80 chr9:130590730-130590810 1.0000 80 chrX:53111538-53111618 1.0000 80 chr14:75593648-75593728 1.0000 80 chr1:59165654-59165734 1.0000 80 chr20:47662944-47663024 1.0000 80 chr20:5100503-5100583 1.0000 80 chr2:128615577-128615657 1.0000 80 chr1:114302060-114302140 1.0000 80 chrX:154444716-154444796 1.0000 80 chr4:178363384-178363464 1.0000 80 chr15:44829350-44829430 1.0000 80 chr12:39836821-39836901 1.0000 80 chr12:58335413-58335493 1.0000 80 chr11:60673918-60673998 1.0000 80 chr12:48592141-48592221 1.0000 80 chr2:223725742-223725822 1.0000 80 chr1:161087760-161087840 1.0000 80 chr4:53578674-53578754 1.0000 80 chr2:219232502-219232582 1.0000 80 chr2:10260694-10260774 1.0000 80 chr1:176176375-176176455 1.0000 80 chr1:25071953-25072033 1.0000 80 chr7:23513859-23513939 1.0000 80 chr5:110848139-110848219 1.0000 80 chr1:118148683-118148763 1.0000 80 chr19:1269643-1269723 1.0000 80 chr6:99963265-99963345 1.0000 80 chr2:32582294-32582374 1.0000 80 chr2:69664489-69664569 1.0000 80 chr9:33025239-33025319 1.0000 80 chr19:34625498-34625578 1.0000 80 chr20:2633280-2633360 1.0000 80 chr17:57970479-57970559 1.0000 80 chr10:101190336-10119041 1.0000 80 chr3:57582979-57583059 1.0000 80 chr11:61100479-61100559 1.0000 80 chr4:186064384-186064464 1.0000 80 chr11:63448946-63449026 1.0000 80 chr10:14880338-14880418 1.0000 80 chr20:45317980-45318060 1.0000 80 chr2:201729295-201729375 1.0000 80 chr12:50236822-50236902 1.0000 80 chr19:42364315-42364395 1.0000 80 chr3:184429653-184429733 1.0000 80 chr15:70391682-70391762 1.0000 80 chr8:55047765-55047845 1.0000 80 chr12:104682634-10468271 1.0000 80 chr3:150321064-150321144 1.0000 80 chrX:41193733-41193813 1.0000 80 chr22:24110075-24110155 1.0000 80 chr4:184365768-184365848 1.0000 80 chrX:71496925-71497005 1.0000 80 chrX:48432999-48433079 1.0000 80 chr21:33032010-33032090 1.0000 80 chr9:35814924-35815004 1.0000 80 chr12:121837913-12183799 1.0000 80 chr11:82868219-82868299 1.0000 80 chr5:151138106-151138186 1.0000 80 chr7:97501512-97501592 1.0000 80 chr2:20101411-20101491 1.0000 80 chr17:78120919-78120999 1.0000 80 chr5:177019197-177019277 1.0000 80 chr5:81574116-81574196 1.0000 80 chr15:59981442-59981522 1.0000 80 chr20:524273-524353 1.0000 80 chr8:59465806-59465886 1.0000 80 chr9:214880-214960 1.0000 80 chr2:45838334-45838414 1.0000 80 chr4:17812612-17812692 1.0000 80 chr12:117628206-11762828 1.0000 80 chr6:26020795-26020875 1.0000 80 chr19:40931824-40931904 1.0000 80 chr2:65283554-65283634 1.0000 80 chr20:21283925-21284005 1.0000 80 chr12:122985273-12298535 1.0000 80 chr3:128968408-128968488 1.0000 80 chr15:75932490-75932570 1.0000 80 chr19:6531153-6531233 1.0000 80 chr3:52719995-52720075 1.0000 80 chr1:236445193-236445273 1.0000 80 chr22:42486685-42486765 1.0000 80 chr14:70234255-70234335 1.0000 80 chr11:47869845-47869925 1.0000 80 chr20:32699837-32699917 1.0000 80 chr10:64893292-64893372 1.0000 80 chr5:140700286-140700366 1.0000 80 chr1:90460721-90460801 1.0000 80 chr11:63953062-63953142 1.0000 80 chr12:53846253-53846333 1.0000 80 chr6:32163847-32163927 1.0000 80 chr3:197518154-197518234 1.0000 80 chr4:7069716-7069796 1.0000 80 chr9:131940477-131940557 1.0000 80 chr3:185655507-185655587 1.0000 80 chr4:139936940-139937020 1.0000 80 chr16:89556939-89557019 1.0000 80 chr1:35658175-35658255 1.0000 80 chr1:76190387-76190467 1.0000 80 chr11:88070782-88070862 1.0000 80 chr17:73851896-73851976 1.0000 80 chr10:64893093-64893173 1.0000 80 chr15:35838182-35838262 1.0000 80 chr17:74068528-74068608 1.0000 80 chrX:118708528-118708608 1.0000 80 chr2:27632342-27632422 1.0000 80 chr5:79552065-79552145 1.0000 80 chr8:94753119-94753199 1.0000 80 chr6:158589393-158589473 1.0000 80 chr17:38975160-38975240 1.0000 80 chr14:100842548-10084262 1.0000 80 chr4:68411072-68411152 1.0000 80 chr9:36190939-36191019 1.0000 80 chr3:49066761-49066841 1.0000 80 chrX:119005687-119005767 1.0000 80 chr19:2950536-2950616 1.0000 80 chr14:70234009-70234089 1.0000 80 chr6:99968928-99969008 1.0000 80 chr10:112632012-11263209 1.0000 80 chr1:43232934-43233014 1.0000 80 chr10:124913941-12491402 1.0000 80 chr1:33430369-33430449 1.0000 80 chr8:42249416-42249496 1.0000 80 chr6:47445722-47445802 1.0000 80 chr5:72794332-72794412 1.0000 80 chr5:176449676-176449756 1.0000 80 chr2:99771489-99771569 1.0000 80 chr1:70876910-70876990 1.0000 80 chr2:192542876-192542956 1.0000 80 chr14:31028355-31028435 1.0000 80 chr1:68962681-68962761 1.0000 80 chr18:19284661-19284741 1.0000 80 chr19:45927057-45927137 1.0000 80 chr17:62207320-62207400 1.0000 80 chr14:73525251-73525331 1.0000 80 chr5:90679139-90679219 1.0000 80 chr2:65454901-65454981 1.0000 80 chr20:49126928-49127008 1.0000 80 chr5:139936966-139937046 1.0000 80 chr16:87350960-87351040 1.0000 80 chr10:28821772-28821852 1.0000 80 chr14:75747976-75748056 1.0000 80 chr12:110939796-11093987 1.0000 80 chr1:207495058-207495138 1.0000 80 chr11:82868418-82868498 1.0000 80 chr1:111506498-111506578 1.0000 80 chr19:38865415-38865495 1.0000 80 chr8:22926171-22926251 1.0000 80 chr19:1269352-1269432 1.0000 80 chr6:8435724-8435804 1.0000 80 chr8:41386776-41386856 1.0000 80 chr12:12510112-12510192 1.0000 80 chr10:81107378-81107458 1.0000 80 chr1:33502310-33502390 1.0000 80 chr17:26926132-26926212 1.0000 80 chr5:133512508-133512588 1.0000 80 chr19:18433798-18433878 1.0000 80 chr12:49075945-49076025 1.0000 80 chr17:34136494-34136574 1.0000 80 chr19:1104048-1104128 1.0000 80 chr17:8113777-8113857 1.0000 80 chr22:47158375-47158455 1.0000 80 chr14:23398501-23398581 1.0000 80 chr19:12845389-12845469 1.0000 80 chr3:48488164-48488244 1.0000 80 chr14:96968591-96968671 1.0000 80 chr17:25621108-25621188 1.0000 80 chr7:115850844-115850924 1.0000 80 chr2:136743013-136743093 1.0000 80 chr19:47363792-47363872 1.0000 80 chr14:90863358-90863438 1.0000 80 chr12:95867903-95867983 1.0000 80 chr18:20513652-20513732 1.0000 80 chr3:52570628-52570708 1.0000 80 chr14:34420176-34420256 1.0000 80 chr5:131826379-131826459 1.0000 80 chr17:73775454-73775534 1.0000 80 chr19:48103867-48103947 1.0000 80 chr16:24550935-24551015 1.0000 80 chr15:75230285-75230365 1.0000 80 chr3:129159206-129159286 1.0000 80 chr2:227700820-227700900 1.0000 80 chr12:104680925-10468100 1.0000 80 chr12:27091401-27091481 1.0000 80 chr18:57026359-57026439 1.0000 80 chr19:58740191-58740271 1.0000 80 chr6:166756090-166756170 1.0000 80 chr11:93474455-93474535 1.0000 80 ******************************************************************************** ******************************************************************************** COMMAND LINE SUMMARY ******************************************************************************** This information can also be useful in the event you wish to report a problem with the MEME software. command: meme -oc ../result/final_prediction/K562/inference_raw/MEME/RankLinear0.6_40_RBFOX2/ -dna -nmotifs 5 -w 8 -maxsize 250000 -nostatus ../result/final_prediction/K562/fasta/RankLinear0.6_40/RBFOX2.fasta model: mod= zoops nmotifs= 5 evt= inf objective function: em= E-value of product of p-values starts= E-value of product of p-values strands: + width: minw= 8 maxw= 8 nsites: minsites= 2 maxsites= 250 wnsites= 0.8 theta: spmap= uni spfuzz= 0.5 em: prior= dirichlet b= 0.01 maxiter= 50 distance= 1e-05 trim: wg= 11 ws= 1 endgaps= yes data: n= 20000 N= 250 sample: seed= 0 hsfrac= 0 searchsize= 20000 norand= no csites= 1000 Letter frequencies in dataset: A 0.152 C 0.344 G 0.351 T 0.153 Background letter frequencies (from file dataset with add-one prior applied): A 0.152 C 0.344 G 0.351 T 0.153 Background model order: 0 ******************************************************************************** ******************************************************************************** MOTIF GCCATCTT MEME-1 width = 8 sites = 17 llr = 184 E-value = 1.2e-008 ******************************************************************************** -------------------------------------------------------------------------------- Motif GCCATCTT MEME-1 Description -------------------------------------------------------------------------------- Simplified A :::a1::: pos.-specific C :aa::9:1 probability G a::::::: matrix T ::::91a9 bits 2.7 * * 2.4 ** * 2.2 ** ** 1.9 ** ** Relative 1.6 ***** ** Entropy 1.4 ***** ** (15.6 bits) 1.1 ******** 0.8 ******** 0.5 ******** 0.3 ******** 0.0 -------- Multilevel GCCATCTT consensus sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GCCATCTT MEME-1 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr14:23398501-23398581 65 7.78e-06 CGCCATCGCC GCCATCTT TCTCCTCG chr12:49075945-49076025 15 7.78e-06 AAAGAGCACC GCCATCTT ACCTCAGGAG chr17:74068528-74068608 40 7.78e-06 CTTCTCAGCA GCCATCTT GCCCCTGCGC chr11:47869845-47869925 21 7.78e-06 TCCCGCCGCC GCCATCTT CCCGCCGTCG chr22:42486685-42486765 59 7.78e-06 GCCGCTCCCC GCCATCTT GCCAAAGCAT chr12:117628206-11762828 51 7.78e-06 tgctgccgcc gccATCTT GTCCGCGTAC chr9:35814924-35815004 48 7.78e-06 CACGGCTGCC GCCATCTT CCCTGAGCCG chr2:69664489-69664569 61 7.78e-06 GGCCGTCGCC GCCATCTT AGTCCGGAGT chr1:161087760-161087840 52 7.78e-06 GCTGTTCTCC GCCATCTT CGCCGCCTGC chr1:46050091-46050171 17 7.78e-06 TTTCGCGGCC GCCATCTT GCCGGGGGCA chr17:42143948-42144028 3 7.78e-06 CC GCCATCTT GGGAGTgcag chr13:27825686-27825766 25 7.78e-06 GGCCGGAACC GCCATCTT CCAGGTAGGG chr17:25621108-25621188 18 1.12e-05 GGCGCCGCCC GCCATTTT GACTCCAGTG chr11:82868219-82868299 12 1.12e-05 CACTGCCGCC GCCATTTT GTGTCTGTGG chr5:110848139-110848219 60 1.90e-05 GGCGACAGCA GCCAACTT GTAAGTCACC chr5:139936966-139937046 67 3.65e-05 GTACAGCTCC GCCATCTC CACTTC chr10:112632012-11263209 45 3.65e-05 CCCTCCCGGA GCCATCTC CCCACTGAGA -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GCCATCTT MEME-1 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr14:23398501-23398581 7.8e-06 64_[+1]_8 chr12:49075945-49076025 7.8e-06 14_[+1]_58 chr17:74068528-74068608 7.8e-06 39_[+1]_33 chr11:47869845-47869925 7.8e-06 20_[+1]_52 chr22:42486685-42486765 7.8e-06 58_[+1]_14 chr12:117628206-11762828 7.8e-06 50_[+1]_22 chr9:35814924-35815004 7.8e-06 47_[+1]_25 chr2:69664489-69664569 7.8e-06 60_[+1]_12 chr1:161087760-161087840 7.8e-06 51_[+1]_21 chr1:46050091-46050171 7.8e-06 16_[+1]_56 chr17:42143948-42144028 7.8e-06 2_[+1]_70 chr13:27825686-27825766 7.8e-06 24_[+1]_48 chr17:25621108-25621188 1.1e-05 17_[+1]_55 chr11:82868219-82868299 1.1e-05 11_[+1]_61 chr5:110848139-110848219 1.9e-05 59_[+1]_13 chr5:139936966-139937046 3.6e-05 66_[+1]_6 chr10:112632012-11263209 3.6e-05 44_[+1]_28 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GCCATCTT MEME-1 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF GCCATCTT width=8 seqs=17 chr14:23398501-23398581 ( 65) GCCATCTT 1 chr12:49075945-49076025 ( 15) GCCATCTT 1 chr17:74068528-74068608 ( 40) GCCATCTT 1 chr11:47869845-47869925 ( 21) GCCATCTT 1 chr22:42486685-42486765 ( 59) GCCATCTT 1 chr12:117628206-11762828 ( 51) GCCATCTT 1 chr9:35814924-35815004 ( 48) GCCATCTT 1 chr2:69664489-69664569 ( 61) GCCATCTT 1 chr1:161087760-161087840 ( 52) GCCATCTT 1 chr1:46050091-46050171 ( 17) GCCATCTT 1 chr17:42143948-42144028 ( 3) GCCATCTT 1 chr13:27825686-27825766 ( 25) GCCATCTT 1 chr17:25621108-25621188 ( 18) GCCATTTT 1 chr11:82868219-82868299 ( 12) GCCATTTT 1 chr5:110848139-110848219 ( 60) GCCAACTT 1 chr5:139936966-139937046 ( 67) GCCATCTC 1 chr10:112632012-11263209 ( 45) GCCATCTC 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GCCATCTT MEME-1 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 10.8621 E= 1.2e-008 -1073 -1073 151 -1073 -1073 154 -1073 -1073 -1073 154 -1073 -1073 272 -1073 -1073 -1073 -137 -1073 -1073 262 -1073 136 -1073 -38 -1073 -1073 -1073 271 -1073 -155 -1073 253 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GCCATCTT MEME-1 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 17 E= 1.2e-008 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.058824 0.000000 0.000000 0.941176 0.000000 0.882353 0.000000 0.117647 0.000000 0.000000 0.000000 1.000000 0.000000 0.117647 0.000000 0.882353 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GCCATCTT MEME-1 regular expression -------------------------------------------------------------------------------- GCCATCTT -------------------------------------------------------------------------------- Time 5.10 secs. ******************************************************************************** ******************************************************************************** MOTIF AGGARRAR MEME-2 width = 8 sites = 26 llr = 230 E-value = 1.4e+000 ******************************************************************************** -------------------------------------------------------------------------------- Motif AGGARRAR MEME-2 Description -------------------------------------------------------------------------------- Simplified A a:3a6477 pos.-specific C ::1::::: probability G :a7:4633 matrix T :::::::: bits 2.7 * * 2.4 * * 2.2 * * 1.9 * * Relative 1.6 ** * Entropy 1.4 ** ** ** (12.7 bits) 1.1 ** ***** 0.8 ** ***** 0.5 ******** 0.3 ******** 0.0 -------- Multilevel AGGAAGAA consensus A GAGG sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AGGARRAR MEME-2 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr2:65454901-65454981 69 5.69e-06 AAGACGCAAG AGGAAGAA GAGA chr11:82868219-82868299 30 7.21e-06 GTGTCTGTGG AGAAAGAA GCTTCTGTGG chr19:2950536-2950616 51 1.07e-05 CAGTACAAGG AGGAGAAA CCGCTCTCAC chrX:154444716-154444796 73 1.07e-05 GTTGTGGCAA AGGAGAAA chr10:5855234-5855314 20 1.57e-05 GACCCGAGCA AGGAAAAG GCGCAGGGGC chr3:185655507-185655587 48 1.73e-05 CGACGGGCCT AGAAAAAG ATGCAAGGAG chr12:49075945-49076025 2 2.08e-05 G AGGAAAGA GCACCGCCAT chr2:128615577-128615657 29 2.08e-05 CCCAACCTTT AGGAAAGA TGAGCTGTGA chr11:88070782-88070862 73 3.04e-05 CAGGGAGCTG AGAAAAGA chr12:58335413-58335493 40 3.04e-05 CGCCTGAGCC AGGAGGAA GCAGCGGCGA chr9:130590730-130590810 13 3.04e-05 GCGCGGCCCC AGGAGGAA GGCGGCGCGG chr3:150264142-150264222 7 3.04e-05 GTGCGC AGGAGGAA GAGAACTGGC chr13:21714682-21714762 58 3.04e-05 CGCAGGCCGT AGGAGGAA GATGGCGGTG chr16:48399750-48399830 8 3.39e-05 CTGGCTG AGAAGGAA GTGCGCTCCC chrX:131157370-131157450 10 4.20e-05 TCGGCGTTC AGGAAGAG GAGCAGCAGC chr11:61100479-61100559 4 4.55e-05 ACT AGAAAGAG GGACACAAGC chr3:57582979-57583059 3 4.55e-05 GA AGAAAGAG GGAGGCAGAA chr5:140700286-140700366 51 5.51e-05 TCGCCTACCC AGCAAAAA CGGAAGTGCT chr5:81574116-81574196 69 5.51e-05 GAAGCACCGC AGGAAGGA GCCA chr11:68039368-68039448 1 5.51e-05 . AGGAAGGA GCCTGAGGCC chr4:68411072-68411152 73 6.20e-05 CAGGAAGCCG AGCAAGAA chr5:173315363-173315443 5 7.02e-05 CCTG AGGAGAAG GACTCAGCCG chr1:236445193-236445273 71 9.34e-05 CGAGTGAGGC AGGAAAGG CG chr5:43313448-43313528 33 9.34e-05 GCGGCAGCAG AGGAAAGG GAGTGAGCCA chr12:12510112-12510192 22 1.24e-04 GCTCCCGGAA AGAAGGAG GGCTAGCCGC chr2:27255834-27255914 30 1.46e-04 GAAGTGGCCG AGGAGGGA GGGCTGCGAG -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AGGARRAR MEME-2 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr2:65454901-65454981 5.7e-06 68_[+2]_4 chr11:82868219-82868299 7.2e-06 29_[+2]_43 chr19:2950536-2950616 1.1e-05 50_[+2]_22 chrX:154444716-154444796 1.1e-05 72_[+2] chr10:5855234-5855314 1.6e-05 19_[+2]_53 chr3:185655507-185655587 1.7e-05 47_[+2]_25 chr12:49075945-49076025 2.1e-05 1_[+2]_71 chr2:128615577-128615657 2.1e-05 28_[+2]_44 chr11:88070782-88070862 3e-05 72_[+2] chr12:58335413-58335493 3e-05 39_[+2]_33 chr9:130590730-130590810 3e-05 12_[+2]_60 chr3:150264142-150264222 3e-05 6_[+2]_66 chr13:21714682-21714762 3e-05 57_[+2]_15 chr16:48399750-48399830 3.4e-05 7_[+2]_65 chrX:131157370-131157450 4.2e-05 9_[+2]_63 chr11:61100479-61100559 4.6e-05 3_[+2]_69 chr3:57582979-57583059 4.6e-05 2_[+2]_70 chr5:140700286-140700366 5.5e-05 50_[+2]_22 chr5:81574116-81574196 5.5e-05 68_[+2]_4 chr11:68039368-68039448 5.5e-05 [+2]_72 chr4:68411072-68411152 6.2e-05 72_[+2] chr5:173315363-173315443 7e-05 4_[+2]_68 chr1:236445193-236445273 9.3e-05 70_[+2]_2 chr5:43313448-43313528 9.3e-05 32_[+2]_40 chr12:12510112-12510192 0.00012 21_[+2]_51 chr2:27255834-27255914 0.00015 29_[+2]_43 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AGGARRAR MEME-2 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF AGGARRAR width=8 seqs=26 chr2:65454901-65454981 ( 69) AGGAAGAA 1 chr11:82868219-82868299 ( 30) AGAAAGAA 1 chr19:2950536-2950616 ( 51) AGGAGAAA 1 chrX:154444716-154444796 ( 73) AGGAGAAA 1 chr10:5855234-5855314 ( 20) AGGAAAAG 1 chr3:185655507-185655587 ( 48) AGAAAAAG 1 chr12:49075945-49076025 ( 2) AGGAAAGA 1 chr2:128615577-128615657 ( 29) AGGAAAGA 1 chr11:88070782-88070862 ( 73) AGAAAAGA 1 chr12:58335413-58335493 ( 40) AGGAGGAA 1 chr9:130590730-130590810 ( 13) AGGAGGAA 1 chr3:150264142-150264222 ( 7) AGGAGGAA 1 chr13:21714682-21714762 ( 58) AGGAGGAA 1 chr16:48399750-48399830 ( 8) AGAAGGAA 1 chrX:131157370-131157450 ( 10) AGGAAGAG 1 chr11:61100479-61100559 ( 4) AGAAAGAG 1 chr3:57582979-57583059 ( 3) AGAAAGAG 1 chr5:140700286-140700366 ( 51) AGCAAAAA 1 chr5:81574116-81574196 ( 69) AGGAAGGA 1 chr11:68039368-68039448 ( 1) AGGAAGGA 1 chr4:68411072-68411152 ( 73) AGCAAGAA 1 chr5:173315363-173315443 ( 5) AGGAGAAG 1 chr1:236445193-236445273 ( 71) AGGAAAGG 1 chr5:43313448-43313528 ( 33) AGGAAAGG 1 chr12:12510112-12510192 ( 22) AGAAGGAG 1 chr2:27255834-27255914 ( 30) AGGAGGGA 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AGGARRAR MEME-2 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 11.3895 E= 1.4e+000 272 -1134 -1134 -1134 -1134 -1134 151 -1134 82 -216 90 -1134 272 -1134 -1134 -1134 202 -1134 13 -1134 148 -1134 72 -1134 219 -1134 -19 -1134 210 -1134 -2 -1134 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AGGARRAR MEME-2 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 26 E= 1.4e+000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.269231 0.076923 0.653846 0.000000 1.000000 0.000000 0.000000 0.000000 0.615385 0.000000 0.384615 0.000000 0.423077 0.000000 0.576923 0.000000 0.692308 0.000000 0.307692 0.000000 0.653846 0.000000 0.346154 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AGGARRAR MEME-2 regular expression -------------------------------------------------------------------------------- AG[GA]A[AG][GA][AG][AG] -------------------------------------------------------------------------------- Time 8.91 secs. ******************************************************************************** ******************************************************************************** MOTIF TCNCCTTY MEME-3 width = 8 sites = 30 llr = 249 E-value = 3.2e+003 ******************************************************************************** -------------------------------------------------------------------------------- Motif TCNCCTTY MEME-3 Description -------------------------------------------------------------------------------- Simplified A ::2::::1 pos.-specific C :735a::6 probability G ::22:::: matrix T a332:aa3 bits 2.7 * ** 2.4 * ** 2.2 * ** 1.9 * ** Relative 1.6 * *** Entropy 1.4 * *** (12.0 bits) 1.1 ** *** 0.8 ** **** 0.5 ** **** 0.3 ******** 0.0 -------- Multilevel TCTCCTTC consensus TCG T sequence AT -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCNCCTTY MEME-3 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr7:56119463-56119543 53 2.19e-06 CTCAGCATCG TTTCCTTT TCCTCCGCTG chr15:44084583-44084663 28 2.19e-06 CTCCTTGCCC TTTTCTTT CCGTTCACCC chr13:27825686-27825766 6 2.19e-06 gccTC TTTCCTTT CGGCCGGAAC chrX:24073055-24073135 10 1.21e-05 CCGGGGTGA TTTCCTTC CTCTTTTGGC chr1:46050091-46050171 62 2.31e-05 CGCCTGCCCC TCTCCTTC CTCCCCCAGC chr2:113403534-113403614 14 2.31e-05 TCTGCGTGGT TCTTCTTC TCGGCCGCTG chr6:7313215-7313295 17 2.31e-05 ATCACTGGCA TCTCCTTC CTGGCCATCC chr12:58335413-58335493 5 2.53e-05 GAGG TTACCTTT CCCAGTCTCG chr2:45838334-45838414 20 5.61e-05 CACGCACAGC TCACCTTC CCGCCCGGCA chr12:104682634-10468271 55 5.61e-05 CACGCTCCGC TCTGCTTT TGTGCCACAC chr19:42364315-42364395 8 5.61e-05 CCCGTCG TTCCCTTT CCCCTGGCTG chr10:101190336-10119041 70 5.61e-05 GAGGAGACAC TCACCTTC ACC chr2:219232502-219232582 52 5.61e-05 GAGGACGTGG TCACCTTC GCCGCCGAGT chr17:73775454-73775534 40 9.18e-05 GAGGAGTCAC TTCCCTTC CTCGACGGGC chr10:81107378-81107458 38 1.23e-04 CGGCGACCCG TCCTCTTC CTCCTCCTCC chrX:118708528-118708608 51 1.23e-04 TGCTTCCGCC TCCCCTTC TCCTGCTTCT chr12:50236822-50236902 6 1.23e-04 TGCGG TCTCCTTA ACACTCCCTC chr1:59165654-59165734 33 1.23e-04 CGCTACCACG TCCCCTTC GATATCCACA chr5:43313448-43313528 73 1.23e-04 CCGCGGCGCC TCCCCTTC chr12:48592141-48592221 51 1.27e-04 GGCGACAGCT TCAGCTTT CAGTGTGAGG chr6:26033612-26033692 69 1.35e-04 CTCGGAGTAG TTGCCTTT GCGG chr11:82868418-82868498 21 1.60e-04 CAGAGCGGCT TCAGCTTC AGCTGCAGCG chr2:227700616-227700696 65 1.73e-04 GGCCGAGCCG TCCGCTTT AAGGCCCT chr14:75747976-75748056 30 2.19e-04 ACGTCTTCCT TCGTCTTC ACCTACCCCG chr1:114302060-114302140 5 2.19e-04 GCGC TCGTCTTC TGCGGGCCGC chr2:234763073-234763153 27 2.19e-04 CAGCAGCTGG TCGTCTTC CACGTCCTCG chr14:96968591-96968671 47 2.45e-04 CCTTAGGAAC TCCGCTTC CCGTGAGGCT chr12:12510112-12510192 2 2.45e-04 G TTCTCTTA GGGCTCCCGG chrX:53111538-53111618 55 2.45e-04 TCTCCTCAGC TCTGCTTA CCGGTGCGAC chrX:48432999-48433079 72 2.59e-04 ACACGTAGGC TTGGCTTT C -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCNCCTTY MEME-3 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr7:56119463-56119543 2.2e-06 52_[+3]_20 chr15:44084583-44084663 2.2e-06 27_[+3]_45 chr13:27825686-27825766 2.2e-06 5_[+3]_67 chrX:24073055-24073135 1.2e-05 9_[+3]_63 chr1:46050091-46050171 2.3e-05 61_[+3]_11 chr2:113403534-113403614 2.3e-05 13_[+3]_59 chr6:7313215-7313295 2.3e-05 16_[+3]_56 chr12:58335413-58335493 2.5e-05 4_[+3]_68 chr2:45838334-45838414 5.6e-05 19_[+3]_53 chr12:104682634-10468271 5.6e-05 54_[+3]_18 chr19:42364315-42364395 5.6e-05 7_[+3]_65 chr10:101190336-10119041 5.6e-05 69_[+3]_3 chr2:219232502-219232582 5.6e-05 51_[+3]_21 chr17:73775454-73775534 9.2e-05 39_[+3]_33 chr10:81107378-81107458 0.00012 37_[+3]_35 chrX:118708528-118708608 0.00012 50_[+3]_22 chr12:50236822-50236902 0.00012 5_[+3]_67 chr1:59165654-59165734 0.00012 32_[+3]_40 chr5:43313448-43313528 0.00012 72_[+3] chr12:48592141-48592221 0.00013 50_[+3]_22 chr6:26033612-26033692 0.00014 68_[+3]_4 chr11:82868418-82868498 0.00016 20_[+3]_52 chr2:227700616-227700696 0.00017 64_[+3]_8 chr14:75747976-75748056 0.00022 29_[+3]_43 chr1:114302060-114302140 0.00022 4_[+3]_68 chr2:234763073-234763153 0.00022 26_[+3]_46 chr14:96968591-96968671 0.00024 46_[+3]_26 chr12:12510112-12510192 0.00024 1_[+3]_71 chrX:53111538-53111618 0.00024 54_[+3]_18 chrX:48432999-48433079 0.00026 71_[+3]_1 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCNCCTTY MEME-3 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF TCNCCTTY width=8 seqs=30 chr7:56119463-56119543 ( 53) TTTCCTTT 1 chr15:44084583-44084663 ( 28) TTTTCTTT 1 chr13:27825686-27825766 ( 6) TTTCCTTT 1 chrX:24073055-24073135 ( 10) TTTCCTTC 1 chr1:46050091-46050171 ( 62) TCTCCTTC 1 chr2:113403534-113403614 ( 14) TCTTCTTC 1 chr6:7313215-7313295 ( 17) TCTCCTTC 1 chr12:58335413-58335493 ( 5) TTACCTTT 1 chr2:45838334-45838414 ( 20) TCACCTTC 1 chr12:104682634-10468271 ( 55) TCTGCTTT 1 chr19:42364315-42364395 ( 8) TTCCCTTT 1 chr10:101190336-10119041 ( 70) TCACCTTC 1 chr2:219232502-219232582 ( 52) TCACCTTC 1 chr17:73775454-73775534 ( 40) TTCCCTTC 1 chr10:81107378-81107458 ( 38) TCCTCTTC 1 chrX:118708528-118708608 ( 51) TCCCCTTC 1 chr12:50236822-50236902 ( 6) TCTCCTTA 1 chr1:59165654-59165734 ( 33) TCCCCTTC 1 chr5:43313448-43313528 ( 73) TCCCCTTC 1 chr12:48592141-48592221 ( 51) TCAGCTTT 1 chr6:26033612-26033692 ( 69) TTGCCTTT 1 chr11:82868418-82868498 ( 21) TCAGCTTC 1 chr2:227700616-227700696 ( 65) TCCGCTTT 1 chr14:75747976-75748056 ( 30) TCGTCTTC 1 chr1:114302060-114302140 ( 5) TCGTCTTC 1 chr2:234763073-234763153 ( 27) TCGTCTTC 1 chr14:96968591-96968671 ( 47) TCCGCTTC 1 chr12:12510112-12510192 ( 2) TTCTCTTA 1 chrX:53111538-53111618 ( 55) TCTGCTTA 1 chrX:48432999-48433079 ( 72) TTGGCTTT 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCNCCTTY MEME-3 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 10.9532 E= 3.2e+003 -1155 -1155 -1155 271 -1155 95 -1155 113 39 -20 -107 113 -1155 63 -59 61 -1155 154 -1155 -1155 -1155 -1155 -1155 271 -1155 -1155 -1155 271 -60 72 -1155 113 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCNCCTTY MEME-3 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 30 E= 3.2e+003 0.000000 0.000000 0.000000 1.000000 0.000000 0.666667 0.000000 0.333333 0.200000 0.300000 0.166667 0.333333 0.000000 0.533333 0.233333 0.233333 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.100000 0.566667 0.000000 0.333333 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCNCCTTY MEME-3 regular expression -------------------------------------------------------------------------------- T[CT][TCA][CGT]CTT[CT] -------------------------------------------------------------------------------- Time 12.65 secs. ******************************************************************************** ******************************************************************************** MOTIF ATGGCGGC MEME-4 width = 8 sites = 13 llr = 126 E-value = 4.3e+004 ******************************************************************************** -------------------------------------------------------------------------------- Motif ATGGCGGC MEME-4 Description -------------------------------------------------------------------------------- Simplified A a:::::3: pos.-specific C ::::a::a probability G ::aa:a7: matrix T :a:::::: bits 2.7 ** 2.4 ** 2.2 ** 1.9 ** Relative 1.6 ****** * Entropy 1.4 ****** * (14.0 bits) 1.1 ******** 0.8 ******** 0.5 ******** 0.3 ******** 0.0 -------- Multilevel ATGGCGGC consensus A sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ATGGCGGC MEME-4 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr19:38865415-38865495 16 5.99e-05 ATCACGCAAG ATGGCGGC CGCGGCGGTG chr1:68962681-68962761 28 5.99e-05 GGTGGCGTCC ATGGCGGC GAAGGCGACA chr15:75932490-75932570 21 5.99e-05 CCGCACCATG ATGGCGGC AGCCGCAGCC chr21:33032010-33032090 73 5.99e-05 CTAGCGAGTT ATGGCGAC chrX:41193733-41193813 40 5.99e-05 GACGAGCACA ATGGCGGC TTTTGTGTGT chr10:14880338-14880418 64 5.99e-05 CTGCTGCCTC ATGGCGGC CATCGGAGT chr17:57970479-57970559 26 5.99e-05 GCAGCCGGTG ATGGCGGC AGCGGCTGTG chr2:32582294-32582374 20 5.99e-05 AGGCCGGAAG ATGGCGGC TGCGGCTGCG chr12:48592141-48592221 39 5.99e-05 CCTCGGAAAT ATGGCGAC AGCTTCAGCT chr15:44829350-44829430 43 5.99e-05 CCGGCTCGAG ATggcggc ggcggcggcg chrX:154444716-154444796 44 5.99e-05 CATCCCCAAG ATGGCGGC CGTTAAGGAC chrX:16804604-16804684 7 5.99e-05 CACCTC ATGGCGAC GCGGGTAGAG chr2:27255834-27255914 50 5.99e-05 GCTGCGAGCC ATGGCGAC CAAGACGGCG -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ATGGCGGC MEME-4 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr19:38865415-38865495 6e-05 15_[+4]_57 chr1:68962681-68962761 6e-05 27_[+4]_45 chr15:75932490-75932570 6e-05 20_[+4]_52 chr21:33032010-33032090 6e-05 72_[+4] chrX:41193733-41193813 6e-05 39_[+4]_33 chr10:14880338-14880418 6e-05 63_[+4]_9 chr17:57970479-57970559 6e-05 25_[+4]_47 chr2:32582294-32582374 6e-05 19_[+4]_53 chr12:48592141-48592221 6e-05 38_[+4]_34 chr15:44829350-44829430 6e-05 42_[+4]_30 chrX:154444716-154444796 6e-05 43_[+4]_29 chrX:16804604-16804684 6e-05 6_[+4]_66 chr2:27255834-27255914 6e-05 49_[+4]_23 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ATGGCGGC MEME-4 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF ATGGCGGC width=8 seqs=13 chr19:38865415-38865495 ( 16) ATGGCGGC 1 chr1:68962681-68962761 ( 28) ATGGCGGC 1 chr15:75932490-75932570 ( 21) ATGGCGGC 1 chr21:33032010-33032090 ( 73) ATGGCGAC 1 chrX:41193733-41193813 ( 40) ATGGCGGC 1 chr10:14880338-14880418 ( 64) ATGGCGGC 1 chr17:57970479-57970559 ( 26) ATGGCGGC 1 chr2:32582294-32582374 ( 20) ATGGCGGC 1 chr12:48592141-48592221 ( 39) ATGGCGAC 1 chr15:44829350-44829430 ( 43) ATGGCGGC 1 chrX:154444716-154444796 ( 44) ATGGCGGC 1 chrX:16804604-16804684 ( 7) ATGGCGAC 1 chr2:27255834-27255914 ( 50) ATGGCGAC 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ATGGCGGC MEME-4 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 10.2095 E= 4.3e+004 272 -1035 -1035 -1035 -1035 -1035 -1035 271 -1035 -1035 151 -1035 -1035 -1035 151 -1035 -1035 154 -1035 -1035 -1035 -1035 151 -1035 102 -1035 98 -1035 -1035 154 -1035 -1035 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ATGGCGGC MEME-4 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 13 E= 4.3e+004 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.307692 0.000000 0.692308 0.000000 0.000000 1.000000 0.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ATGGCGGC MEME-4 regular expression -------------------------------------------------------------------------------- ATGGCG[GA]C -------------------------------------------------------------------------------- Time 16.26 secs. ******************************************************************************** ******************************************************************************** MOTIF TAMWAAAA MEME-5 width = 8 sites = 2 llr = 27 E-value = 4.9e+004 ******************************************************************************** -------------------------------------------------------------------------------- Motif TAMWAAAA MEME-5 Description -------------------------------------------------------------------------------- Simplified A :a55aaaa pos.-specific C ::5::::: probability G :::::::: matrix T a::5:::: bits 2.7 ** **** 2.4 ** **** 2.2 ** **** 1.9 ** **** Relative 1.6 ** ***** Entropy 1.4 ** ***** (19.1 bits) 1.1 ******** 0.8 ******** 0.5 ******** 0.3 ******** 0.0 -------- Multilevel TAAAAAAA consensus CT sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TAMWAAAA MEME-5 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr1:70876910-70876990 11 5.76e-07 GCAGACCCGC TAATAAAA TCCACCCCAA chr5:72794332-72794412 53 1.88e-06 TCCGACAAGG TACAAAAA GGCTCTGGAC -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TAMWAAAA MEME-5 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr1:70876910-70876990 5.8e-07 10_[+5]_62 chr5:72794332-72794412 1.9e-06 52_[+5]_20 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TAMWAAAA MEME-5 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF TAMWAAAA width=8 seqs=2 chr1:70876910-70876990 ( 11) TAATAAAA 1 chr5:72794332-72794412 ( 53) TACAAAAA 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TAMWAAAA MEME-5 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 13.1555 E= 4.9e+004 -765 -765 -765 270 271 -765 -765 -765 171 54 -765 -765 171 -765 -765 171 271 -765 -765 -765 271 -765 -765 -765 271 -765 -765 -765 271 -765 -765 -765 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TAMWAAAA MEME-5 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 2 E= 4.9e+004 0.000000 0.000000 0.000000 1.000000 1.000000 0.000000 0.000000 0.000000 0.500000 0.500000 0.000000 0.000000 0.500000 0.000000 0.000000 0.500000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TAMWAAAA MEME-5 regular expression -------------------------------------------------------------------------------- TA[AC][AT]AAAA -------------------------------------------------------------------------------- Time 19.86 secs. ******************************************************************************** ******************************************************************************** SUMMARY OF MOTIFS ******************************************************************************** -------------------------------------------------------------------------------- Combined block diagrams: non-overlapping sites with p-value < 0.0001 -------------------------------------------------------------------------------- SEQUENCE NAME COMBINED P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr10:126107433-12610751 9.71e-01 80 chr2:74405871-74405951 8.24e-01 80 chr3:156272729-156272809 2.65e-01 80 chr9:80912136-80912216 1.23e-01 80 chr12:6579789-6579869 8.27e-01 80 chr8:82644632-82644712 5.80e-01 80 chr13:27825686-27825766 9.06e-05 5_[+3(2.19e-06)]_11_[+1(7.78e-06)]_\ 48 chr2:234763073-234763153 1.01e-01 80 chr2:27255834-27255914 8.00e-03 49_[+4(5.99e-05)]_23 chr10:5855234-5855314 1.44e-02 19_[+2(1.57e-05)]_53 chrX:48776211-48776291 1.42e-01 80 chr14:20937579-20937659 8.09e-01 80 chr22:22863003-22863083 9.77e-01 80 chr2:106015366-106015446 7.86e-01 80 chr22:39916939-39917019 8.29e-01 80 chr15:44084583-44084663 2.08e-03 27_[+3(2.19e-06)]_45 chr12:104324261-10432434 4.06e-01 80 chr5:43313448-43313528 1.77e-02 32_[+2(9.34e-05)]_40 chr19:14640425-14640505 9.08e-01 80 chr13:21714682-21714762 2.50e-02 57_[+2(3.04e-05)]_15 chr17:42143948-42144028 3.77e-02 2_[+1(7.78e-06)]_70 chr5:148930796-148930876 1.28e-01 80 chr16:48399750-48399830 2.03e-02 7_[+2(3.39e-05)]_65 chr16:74640907-74640987 5.69e-01 80 chr1:184943270-184943350 7.12e-01 80 chr10:120840198-12084027 3.35e-01 80 chrX:118925475-118925555 2.81e-01 80 chrX:16804604-16804684 8.22e-02 6_[+4(5.99e-05)]_66 chrX:131157370-131157450 6.25e-02 9_[+2(4.20e-05)]_63 chr8:47529088-47529168 3.31e-01 80 chr22:29196437-29196517 7.03e-01 80 chr9:3526599-3526679 4.64e-01 80 chr8:87520791-87520871 1.98e-01 80 chr6:83902908-83902988 1.53e-01 80 chr2:198318286-198318366 4.66e-01 80 chr13:96329382-96329462 9.46e-01 80 chr6:26033612-26033692 9.30e-02 80 chr11:70049468-70049548 7.87e-01 80 chr16:30456892-30456972 5.69e-01 80 chr3:169482526-169482606 3.64e-01 80 chr9:37485965-37486045 2.04e-01 80 chr6:7313215-7313295 2.39e-02 16_[+3(2.31e-05)]_56 chr17:16342514-16342594 9.39e-01 80 chr2:113403534-113403614 1.24e-01 13_[+3(2.31e-05)]_59 chrX:129116581-129116661 5.59e-01 80 chr2:227700616-227700696 2.42e-01 80 chr11:64937665-64937745 3.57e-01 80 chr7:56119463-56119543 3.47e-02 52_[+3(2.19e-06)]_20 chr4:24586053-24586133 2.23e-01 80 chr11:126173818-12617389 9.65e-01 80 chr1:46050091-46050171 1.27e-03 16_[+1(7.78e-06)]_37_[+3(2.31e-05)]_\ 11 chrX:24073055-24073135 1.22e-03 9_[+3(1.21e-05)]_63 chr11:68039368-68039448 2.05e-01 [+2(5.51e-05)]_72 chr5:173315363-173315443 8.91e-02 4_[+2(7.02e-05)]_68 chr1:151512762-151512842 8.98e-01 80 chr2:201981296-201981376 9.98e-01 80 chrX:16737766-16737846 5.22e-01 80 chr22:36877560-36877640 7.99e-01 80 chrX:23801276-23801356 7.55e-01 80 chr13:31191622-31191702 9.75e-01 80 chr3:150264142-150264222 1.61e-02 6_[+2(3.04e-05)]_66 chr12:76478330-76478410 6.87e-01 80 chr17:62501850-62501930 3.88e-01 80 chr9:130590730-130590810 1.03e-02 12_[+2(3.04e-05)]_60 chrX:53111538-53111618 1.90e-01 80 chr14:75593648-75593728 5.53e-01 80 chr1:59165654-59165734 1.19e-01 80 chr20:47662944-47663024 2.54e-01 80 chr20:5100503-5100583 3.79e-03 80 chr2:128615577-128615657 7.38e-03 28_[+2(2.08e-05)]_44 chr1:114302060-114302140 2.93e-01 80 chrX:154444716-154444796 1.25e-03 43_[+4(5.99e-05)]_21_[+2(1.07e-05)] chr4:178363384-178363464 9.26e-02 80 chr15:44829350-44829430 4.90e-02 42_[+4(5.99e-05)]_30 chr12:39836821-39836901 7.68e-01 80 chr12:58335413-58335493 4.75e-04 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