******************************************************************************** MEME - Motif discovery tool ******************************************************************************** MEME version 5.3.3 (Release date: Sun Feb 7 15:39:52 2021 -0800) For further information on how to interpret these results please access https://meme-suite.org/meme. To get a copy of the MEME Suite software please access https://meme-suite.org. ******************************************************************************** ******************************************************************************** REFERENCE ******************************************************************************** If you use this program in your research, please cite: Timothy L. Bailey and Charles Elkan, "Fitting a mixture model by expectation maximization to discover motifs in biopolymers", Proceedings of the Second International Conference on Intelligent Systems for Molecular Biology, pp. 28-36, AAAI Press, Menlo Park, California, 1994. ******************************************************************************** ******************************************************************************** TRAINING SET ******************************************************************************** PRIMARY SEQUENCES= ../result/final_prediction/K562/fasta/RankLinear0.6_40/RB1.fasta CONTROL SEQUENCES= --none-- ALPHABET= ACGT Sequence name Weight Length Sequence name Weight Length ------------- ------ ------ ------------- ------ ------ chr8:12458968-12459048 1.0000 80 chr9:133336721-133336801 1.0000 80 chr5:150036158-150036238 1.0000 80 chr20:656289-656369 1.0000 80 chr19:46532329-46532409 1.0000 80 chr11:75863332-75863412 1.0000 80 chr5:176005456-176005536 1.0000 80 chr3:196729970-196730050 1.0000 80 chr7:54841998-54842078 1.0000 80 chr16:3033778-3033858 1.0000 80 chr16:66785610-66785690 1.0000 80 chr9:33720203-33720283 1.0000 80 chr18:45275647-45275727 1.0000 80 chr15:41234158-41234238 1.0000 80 chr1:9555453-9555533 1.0000 80 chr11:46368922-46369002 1.0000 80 chr1:46269169-46269249 1.0000 80 chr16:50402854-50402934 1.0000 80 chr22:20273396-20273476 1.0000 80 chr8:143808494-143808574 1.0000 80 chr6:140469609-140469689 1.0000 80 chr7:155137674-155137754 1.0000 80 chr1:208042526-208042606 1.0000 80 chr19:18272196-18272276 1.0000 80 chr7:50535861-50535941 1.0000 80 chr21:33104588-33104668 1.0000 80 chr16:30662745-30662825 1.0000 80 chr19:34262589-34262669 1.0000 80 chr7:149484638-149484718 1.0000 80 chr10:79606578-79606658 1.0000 80 chr15:44119181-44119261 1.0000 80 chr12:7126213-7126293 1.0000 80 chr1:29562975-29563055 1.0000 80 chr22:20255935-20256015 1.0000 80 chr6:33739409-33739489 1.0000 80 chr22:18507290-18507370 1.0000 80 chr21:37757676-37757756 1.0000 80 chr20:49411410-49411490 1.0000 80 chr16:88870141-88870221 1.0000 80 chr15:48624363-48624443 1.0000 80 chr19:46282673-46282753 1.0000 80 chr7:2710754-2710834 1.0000 80 chr6:34122628-34122708 1.0000 80 chr10:46951456-46951536 1.0000 80 chr6:34495136-34495216 1.0000 80 chr6:37137547-37137627 1.0000 80 chr1:226309302-226309382 1.0000 80 chr17:33446818-33446898 1.0000 80 chr7:100253999-100254079 1.0000 80 chr6:157695857-157695937 1.0000 80 chr16:85722530-85722610 1.0000 80 chr3:140950571-140950651 1.0000 80 chr1:937330-937410 1.0000 80 chr19:16222141-16222221 1.0000 80 chr11:2554134-2554214 1.0000 80 chr1:805271-805351 1.0000 80 chr12:110318317-11031839 1.0000 80 chr15:66914607-66914687 1.0000 80 chr3:6549395-6549475 1.0000 80 chr1:12719098-12719178 1.0000 80 chr19:10982043-10982123 1.0000 80 chr2:27309460-27309540 1.0000 80 chr16:19897683-19897763 1.0000 80 chr22:20287369-20287449 1.0000 80 chr6:26924704-26924784 1.0000 80 chr13:33160502-33160582 1.0000 80 chr22:23226291-23226371 1.0000 80 chr8:26435184-26435264 1.0000 80 chr1:144886724-144886804 1.0000 80 chr3:58477659-58477739 1.0000 80 chr14:105512173-10551225 1.0000 80 chr17:47653098-47653178 1.0000 80 chr7:105517155-105517235 1.0000 80 chr19:14185985-14186065 1.0000 80 chr19:10138487-10138567 1.0000 80 chr17:60501134-60501214 1.0000 80 chr15:65579199-65579279 1.0000 80 chr1:31867658-31867738 1.0000 80 chr1:181999200-181999280 1.0000 80 chr2:20850875-20850955 1.0000 80 chr1:180502805-180502885 1.0000 80 chr11:69458182-69458262 1.0000 80 chr10:121632313-12163239 1.0000 80 chr20:32274168-32274248 1.0000 80 chr6:34759758-34759838 1.0000 80 chr15:40799366-40799446 1.0000 80 chr3:13461865-13461945 1.0000 80 chr11:9595067-9595147 1.0000 80 chr2:8825988-8826068 1.0000 80 chr7:84509887-84509967 1.0000 80 chr19:15543570-15543650 1.0000 80 chr14:105071189-10507126 1.0000 80 chr8:145597558-145597638 1.0000 80 chr6:90539464-90539544 1.0000 80 chr5:1645114-1645194 1.0000 80 chr1:225662783-225662863 1.0000 80 chr11:93276549-93276629 1.0000 80 chr12:58026939-58027019 1.0000 80 chr2:243153819-243153899 1.0000 80 chr21:40720819-40720899 1.0000 80 chr12:102224701-10222478 1.0000 80 chr19:797868-797948 1.0000 80 chr12:54610945-54611025 1.0000 80 chr16:89641184-89641264 1.0000 80 chr22:19711719-19711799 1.0000 80 chr11:111472785-11147286 1.0000 80 chr9:129622692-129622772 1.0000 80 chr4:57410881-57410961 1.0000 80 chr16:1979819-1979899 1.0000 80 chr16:3019215-3019295 1.0000 80 chr17:34838915-34838995 1.0000 80 chr6:40995861-40995941 1.0000 80 chr15:56285847-56285927 1.0000 80 chr17:79917736-79917816 1.0000 80 chr16:57610432-57610512 1.0000 80 chr17:43971745-43971825 1.0000 80 chr9:132372872-132372952 1.0000 80 chr19:48867540-48867620 1.0000 80 chr16:67189384-67189464 1.0000 80 chr1:33177945-33178025 1.0000 80 chr21:34960941-34961021 1.0000 80 chr16:89160211-89160291 1.0000 80 chr7:100609561-100609641 1.0000 80 chr2:48010233-48010313 1.0000 80 chr1:26490830-26490910 1.0000 80 chr12:27167349-27167429 1.0000 80 chr18:8609356-8609436 1.0000 80 chr12:50101425-50101505 1.0000 80 chr17:79075649-79075729 1.0000 80 chr16:11439266-11439346 1.0000 80 chr1:155197501-155197581 1.0000 80 chr7:75831130-75831210 1.0000 80 chr19:1568482-1568562 1.0000 80 chr6:35420147-35420227 1.0000 80 chr11:9779798-9779878 1.0000 80 chr19:47141933-47142013 1.0000 80 chr1:32966342-32966422 1.0000 80 chr10:49864444-49864524 1.0000 80 chr7:154794926-154795006 1.0000 80 chr3:12851664-12851744 1.0000 80 chr9:140149677-140149757 1.0000 80 chr20:5100006-5100086 1.0000 80 chr1:211307497-211307577 1.0000 80 chr19:13076319-13076399 1.0000 80 chr22:22936652-22936732 1.0000 80 chr1:91966527-91966607 1.0000 80 chr22:35795921-35796001 1.0000 80 chr5:139348485-139348565 1.0000 80 chr19:34269068-34269148 1.0000 80 chr1:23670405-23670485 1.0000 80 chr16:30913595-30913675 1.0000 80 chr1:36348674-36348754 1.0000 80 chr19:14184317-14184397 1.0000 80 chr9:139886931-139887011 1.0000 80 chr19:50184076-50184156 1.0000 80 chr2:136634044-136634124 1.0000 80 chr11:3876262-3876342 1.0000 80 chr4:1242967-1243047 1.0000 80 chr12:56583427-56583507 1.0000 80 chr1:32170905-32170985 1.0000 80 chr6:107435531-107435611 1.0000 80 chr19:982824-982904 1.0000 80 chr7:47294139-47294219 1.0000 80 chr16:21566307-21566387 1.0000 80 chr19:40336347-40336427 1.0000 80 chr3:47563726-47563806 1.0000 80 chr11:67033758-67033838 1.0000 80 chr2:10575183-10575263 1.0000 80 chr22:23053360-23053440 1.0000 80 chr6:107349337-107349417 1.0000 80 chr19:49164342-49164422 1.0000 80 chr1:11741170-11741250 1.0000 80 chr11:74303585-74303665 1.0000 80 chr16:56459473-56459553 1.0000 80 chr2:130939167-130939247 1.0000 80 chr7:43878596-43878676 1.0000 80 chr10:73533302-73533382 1.0000 80 chr22:23412266-23412346 1.0000 80 chr1:211688924-211689004 1.0000 80 chr7:6629577-6629657 1.0000 80 chr11:65790033-65790113 1.0000 80 chr7:36406850-36406930 1.0000 80 chr15:75494343-75494423 1.0000 80 chr10:72142414-72142494 1.0000 80 chr12:1905346-1905426 1.0000 80 chr22:21457229-21457309 1.0000 80 chr19:591681-591761 1.0000 80 chr1:12679988-12680068 1.0000 80 chr2:177005428-177005508 1.0000 80 chr10:76995807-76995887 1.0000 80 chr7:116166243-116166323 1.0000 80 chr17:79196802-79196882 1.0000 80 chr17:62915609-62915689 1.0000 80 chr2:71222022-71222102 1.0000 80 chr1:226150224-226150304 1.0000 80 chr1:223307166-223307246 1.0000 80 chr3:32823079-32823159 1.0000 80 chr6:41754310-41754390 1.0000 80 chr1:212606148-212606228 1.0000 80 chr1:175403566-175403646 1.0000 80 chr11:32914109-32914189 1.0000 80 chr2:132250551-132250631 1.0000 80 chr10:72968935-72969015 1.0000 80 chr9:134615541-134615621 1.0000 80 chr11:65547570-65547650 1.0000 80 chr22:23470728-23470808 1.0000 80 chr13:37573490-37573570 1.0000 80 chr19:1240355-1240435 1.0000 80 chr7:152133864-152133944 1.0000 80 chrX:129194575-129194655 1.0000 80 chr22:23052339-23052419 1.0000 80 chr10:44806611-44806691 1.0000 80 chr8:145669615-145669695 1.0000 80 chr3:196439233-196439313 1.0000 80 chr19:5804097-5804177 1.0000 80 chr5:150827041-150827121 1.0000 80 chr12:1059071-1059151 1.0000 80 chr1:17033975-17034055 1.0000 80 chr20:30200773-30200853 1.0000 80 chr19:41140554-41140634 1.0000 80 chrX:153707392-153707472 1.0000 80 chr12:64237711-64237791 1.0000 80 chr1:114889270-114889350 1.0000 80 chr7:50517977-50518057 1.0000 80 chr12:57146053-57146133 1.0000 80 chr19:19285953-19286033 1.0000 80 chr22:50946647-50946727 1.0000 80 chr22:23027568-23027648 1.0000 80 chr11:129566073-12956615 1.0000 80 chr17:42287881-42287961 1.0000 80 chr11:798248-798328 1.0000 80 chr5:175843561-175843641 1.0000 80 chr11:76510391-76510471 1.0000 80 chr11:46260806-46260886 1.0000 80 chr1:6844896-6844976 1.0000 80 chr2:114341549-114341629 1.0000 80 chr10:70167032-70167112 1.0000 80 chr22:20144667-20144747 1.0000 80 chr5:130500301-130500381 1.0000 80 chr3:196696851-196696931 1.0000 80 chr13:53024820-53024900 1.0000 80 chr16:89894973-89895053 1.0000 80 chr1:16400127-16400207 1.0000 80 chr15:64445882-64445962 1.0000 80 chr2:58468528-58468608 1.0000 80 chr1:1677863-1677943 1.0000 80 chr16:1543424-1543504 1.0000 80 chr22:23112872-23112952 1.0000 80 chr10:103911793-10391187 1.0000 80 chr1:151253798-151253878 1.0000 80 ******************************************************************************** ******************************************************************************** COMMAND LINE SUMMARY ******************************************************************************** This information can also be useful in the event you wish to report a problem with the MEME software. command: meme -oc ../result/final_prediction/K562/inference_raw/MEME/RankLinear0.6_40_RB1/ -dna -nmotifs 5 -w 8 -maxsize 250000 -nostatus ../result/final_prediction/K562/fasta/RankLinear0.6_40/RB1.fasta model: mod= zoops nmotifs= 5 evt= inf objective function: em= E-value of product of p-values starts= E-value of product of p-values strands: + width: minw= 8 maxw= 8 nsites: minsites= 2 maxsites= 250 wnsites= 0.8 theta: spmap= uni spfuzz= 0.5 em: prior= dirichlet b= 0.01 maxiter= 50 distance= 1e-05 trim: wg= 11 ws= 1 endgaps= yes data: n= 20000 N= 250 sample: seed= 0 hsfrac= 0 searchsize= 20000 norand= no csites= 1000 Letter frequencies in dataset: A 0.128 C 0.372 G 0.37 T 0.131 Background letter frequencies (from file dataset with add-one prior applied): A 0.128 C 0.372 G 0.37 T 0.131 Background model order: 0 ******************************************************************************** ******************************************************************************** MOTIF GCGGGAAV MEME-1 width = 8 sites = 45 llr = 411 E-value = 1.2e-026 ******************************************************************************** -------------------------------------------------------------------------------- Motif GCGGGAAV MEME-1 Description -------------------------------------------------------------------------------- Simplified A :::::aa5 pos.-specific C :a:1:::3 probability G a:a9a::3 matrix T :::::::: bits 3.0 ** 2.7 ** 2.4 ** 2.1 ** Relative 1.8 ** Entropy 1.5 *** *** (13.2 bits) 1.2 *** *** 0.9 ******* 0.6 ******** 0.3 ******** 0.0 -------- Multilevel GCGGGAAA consensus C sequence G -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GCGGGAAV MEME-1 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr1:151253798-151253878 8 1.46e-05 ACAAAGC GCGGGAAA ACTCGACCTT chr10:103911793-10391187 19 1.46e-05 CAGCAGGGGC GCGGGAAA CCGCTGCTCT chr2:130939167-130939247 41 1.46e-05 CCGCGGCCGG GCGGGAAA AGCGCTTCCA chr19:40336347-40336427 24 1.46e-05 AGTGCAGAAG GCGGGAAA GTGAGCCGAA chr1:23670405-23670485 13 1.46e-05 GCGAGCGGAG GCGGGAAA AGCACGGCCG chr19:13076319-13076399 68 1.46e-05 AGGGGAGGGC GCGGGAAA GGCTG chr16:11439266-11439346 21 1.46e-05 CTCAAAGTTG GCGGGAAA GCGGAGGCGG chr19:48867540-48867620 55 1.46e-05 GAGCGAAAAG GCGGGAAA AAGCGGAACC chr10:121632313-12163239 44 1.46e-05 TCGCACAATG GCGGGAAA TAGCCGCCGC chr14:105512173-10551225 49 1.46e-05 GCGGCTACTA GCGGGAAA GCGAAACCCG chr1:937330-937410 37 1.46e-05 CTGGGCCCGG GCGGGAAA GCCCGCGAGC chr16:88870141-88870221 21 1.46e-05 cagggcgccc gcgggAAA TTTGGCGGGA chr7:149484638-149484718 26 1.46e-05 GTGAGTGCAG GCGGGAAA GCAGGAAGGG chr16:50402854-50402934 63 1.46e-05 cggcgcAGAG GCGGGAAA GAAGGCCCGC chr1:9555453-9555533 47 1.46e-05 GGCAGGAAGC GCGGGAAA GCGGCCGCGA chr7:54841998-54842078 66 1.46e-05 CTGCTCGGAG GCGGGAAA CCCTGCA chr2:58468528-58468608 25 9.94e-05 CCCAGCCTTG GCGGGAAG ATCCTGGAGG chr11:129566073-12956615 25 9.94e-05 GTGTTTCTGG GCGGGAAG GGCTGGGCCA chr22:50946647-50946727 18 9.94e-05 ATTTTCCTGG GCGGGAAC AGCAAAATGG chr12:57146053-57146133 72 9.94e-05 ACAGGAATTG GCGGGAAC A chr11:32914109-32914189 23 9.94e-05 GCTGCGGAAG GCGGGAAG TCTGCGGTTC chr1:211688924-211689004 35 9.94e-05 CGTCCCGACC GCGGGAAG CCGGCGGGGC chr3:47563726-47563806 2 9.94e-05 A GCGGGAAG CAGCCTTGGG chr6:107435531-107435611 38 9.94e-05 CTCCTGGGCA GCGGGAAC CGCGAACCGC chr19:1568482-1568562 21 9.94e-05 CGGCGCTCGG GCGGGAAC CCGGGCGCAT chr16:3019215-3019295 63 9.94e-05 TGGCCGGCCG GCGGGAAC TAGGAGCCTG chr5:1645114-1645194 12 9.94e-05 GGTGAGAACC GCGGGAAC GAACTAACGC chr6:90539464-90539544 24 9.94e-05 CCTTCCAAAG GCGGGAAC TAGTTGTGGG chr14:105071189-10507126 25 9.94e-05 TCGGCCGAGC GCGGGAAG CGCCTGCGGT chr7:84509887-84509967 25 9.94e-05 agaggcgccg gcgggaac ccgggctgcg chr3:13461865-13461945 15 9.94e-05 GGGCCTGAGC GCGGGAAC TCTGGGGGCC chr1:181999200-181999280 62 9.94e-05 TTTGGAGCGC GCGGGAAC CGGACGCCCG chr11:2554134-2554214 33 9.94e-05 GGGCCAGGCG GCGGGAAG GCCTGTAGAC chr21:37757676-37757756 12 9.94e-05 CCTGCGGCGC GCGGGAAG CGGCGCGCGC chr12:7126213-7126293 36 9.94e-05 TAACGGGGAG GCGGGAAC GCCCGCGCCG chr15:44119181-44119261 17 9.94e-05 CGCAATCTTG GCGGGAAG GCGCCGGCCG chr15:41234158-41234238 8 9.94e-05 cgcggcc gcgggaag cggagccgcg chr9:33720203-33720283 14 9.94e-05 GTGTTTTTGG GCGGGAAG GGCTGGGCCA chr3:196729970-196730050 70 9.94e-05 GCGGCGGTTG GCGGGAAg ggc chr5:176005456-176005536 23 9.94e-05 GCCACAGACG GCGGGAAC CTGTCCTCCT chr20:5100006-5100086 13 1.14e-04 TGTGACTTTG GCGCGAAA AAGCAGGTTC chr8:26435184-26435264 44 1.14e-04 CGAAGAAAGC GCGCGAAA GGCGCGCTCC chr18:45275647-45275727 51 1.14e-04 AAGGGCAGCC GCGCGAAA CCCGACGCTC chr5:150036158-150036238 51 1.14e-04 GGCGCTTCTG GCGCGAAA CATCATCAAT chr20:30200773-30200853 40 1.19e-04 GCCACCGTGG GCGAGAAA GGCGGCCTGG -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GCGGGAAV MEME-1 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr1:151253798-151253878 1.5e-05 7_[+1]_65 chr10:103911793-10391187 1.5e-05 18_[+1]_54 chr2:130939167-130939247 1.5e-05 40_[+1]_32 chr19:40336347-40336427 1.5e-05 23_[+1]_49 chr1:23670405-23670485 1.5e-05 12_[+1]_60 chr19:13076319-13076399 1.5e-05 67_[+1]_5 chr16:11439266-11439346 1.5e-05 20_[+1]_52 chr19:48867540-48867620 1.5e-05 54_[+1]_18 chr10:121632313-12163239 1.5e-05 43_[+1]_29 chr14:105512173-10551225 1.5e-05 48_[+1]_24 chr1:937330-937410 1.5e-05 36_[+1]_36 chr16:88870141-88870221 1.5e-05 20_[+1]_52 chr7:149484638-149484718 1.5e-05 25_[+1]_47 chr16:50402854-50402934 1.5e-05 62_[+1]_10 chr1:9555453-9555533 1.5e-05 46_[+1]_26 chr7:54841998-54842078 1.5e-05 65_[+1]_7 chr2:58468528-58468608 9.9e-05 24_[+1]_48 chr11:129566073-12956615 9.9e-05 24_[+1]_48 chr22:50946647-50946727 9.9e-05 17_[+1]_55 chr12:57146053-57146133 9.9e-05 71_[+1]_1 chr11:32914109-32914189 9.9e-05 22_[+1]_50 chr1:211688924-211689004 9.9e-05 34_[+1]_38 chr3:47563726-47563806 9.9e-05 1_[+1]_71 chr6:107435531-107435611 9.9e-05 37_[+1]_35 chr19:1568482-1568562 9.9e-05 20_[+1]_52 chr16:3019215-3019295 9.9e-05 62_[+1]_10 chr5:1645114-1645194 9.9e-05 11_[+1]_61 chr6:90539464-90539544 9.9e-05 23_[+1]_49 chr14:105071189-10507126 9.9e-05 24_[+1]_48 chr7:84509887-84509967 9.9e-05 24_[+1]_48 chr3:13461865-13461945 9.9e-05 14_[+1]_58 chr1:181999200-181999280 9.9e-05 61_[+1]_11 chr11:2554134-2554214 9.9e-05 32_[+1]_40 chr21:37757676-37757756 9.9e-05 11_[+1]_61 chr12:7126213-7126293 9.9e-05 35_[+1]_37 chr15:44119181-44119261 9.9e-05 16_[+1]_56 chr15:41234158-41234238 9.9e-05 7_[+1]_65 chr9:33720203-33720283 9.9e-05 13_[+1]_59 chr3:196729970-196730050 9.9e-05 69_[+1]_3 chr5:176005456-176005536 9.9e-05 22_[+1]_50 chr20:5100006-5100086 0.00011 12_[+1]_60 chr8:26435184-26435264 0.00011 43_[+1]_29 chr18:45275647-45275727 0.00011 50_[+1]_22 chr5:150036158-150036238 0.00011 50_[+1]_22 chr20:30200773-30200853 0.00012 39_[+1]_33 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GCGGGAAV MEME-1 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF GCGGGAAV width=8 seqs=45 chr1:151253798-151253878 ( 8) GCGGGAAA 1 chr10:103911793-10391187 ( 19) GCGGGAAA 1 chr2:130939167-130939247 ( 41) GCGGGAAA 1 chr19:40336347-40336427 ( 24) GCGGGAAA 1 chr1:23670405-23670485 ( 13) GCGGGAAA 1 chr19:13076319-13076399 ( 68) GCGGGAAA 1 chr16:11439266-11439346 ( 21) GCGGGAAA 1 chr19:48867540-48867620 ( 55) GCGGGAAA 1 chr10:121632313-12163239 ( 44) GCGGGAAA 1 chr14:105512173-10551225 ( 49) GCGGGAAA 1 chr1:937330-937410 ( 37) GCGGGAAA 1 chr16:88870141-88870221 ( 21) GCGGGAAA 1 chr7:149484638-149484718 ( 26) GCGGGAAA 1 chr16:50402854-50402934 ( 63) GCGGGAAA 1 chr1:9555453-9555533 ( 47) GCGGGAAA 1 chr7:54841998-54842078 ( 66) GCGGGAAA 1 chr2:58468528-58468608 ( 25) GCGGGAAG 1 chr11:129566073-12956615 ( 25) GCGGGAAG 1 chr22:50946647-50946727 ( 18) GCGGGAAC 1 chr12:57146053-57146133 ( 72) GCGGGAAC 1 chr11:32914109-32914189 ( 23) GCGGGAAG 1 chr1:211688924-211689004 ( 35) GCGGGAAG 1 chr3:47563726-47563806 ( 2) GCGGGAAG 1 chr6:107435531-107435611 ( 38) GCGGGAAC 1 chr19:1568482-1568562 ( 21) GCGGGAAC 1 chr16:3019215-3019295 ( 63) GCGGGAAC 1 chr5:1645114-1645194 ( 12) GCGGGAAC 1 chr6:90539464-90539544 ( 24) GCGGGAAC 1 chr14:105071189-10507126 ( 25) GCGGGAAG 1 chr7:84509887-84509967 ( 25) GCGGGAAC 1 chr3:13461865-13461945 ( 15) GCGGGAAC 1 chr1:181999200-181999280 ( 62) GCGGGAAC 1 chr11:2554134-2554214 ( 33) GCGGGAAG 1 chr21:37757676-37757756 ( 12) GCGGGAAG 1 chr12:7126213-7126293 ( 36) GCGGGAAC 1 chr15:44119181-44119261 ( 17) GCGGGAAG 1 chr15:41234158-41234238 ( 8) GCGGGAAG 1 chr9:33720203-33720283 ( 14) GCGGGAAG 1 chr3:196729970-196730050 ( 70) GCGGGAAG 1 chr5:176005456-176005536 ( 23) GCGGGAAC 1 chr20:5100006-5100086 ( 13) GCGCGAAA 1 chr8:26435184-26435264 ( 44) GCGCGAAA 1 chr18:45275647-45275727 ( 51) GCGCGAAA 1 chr5:150036158-150036238 ( 51) GCGCGAAA 1 chr20:30200773-30200853 ( 40) GCGAGAAA 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GCGGGAAV MEME-1 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 9.70763 E= 1.2e-026 -1214 -1214 144 -1214 -1214 143 -1214 -1214 -1214 -1214 144 -1214 -252 -206 127 -1214 -1214 -1214 144 -1214 297 -1214 -1214 -1214 297 -1214 -1214 -1214 187 -48 -47 -1214 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GCGGGAAV MEME-1 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 45 E= 1.2e-026 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.022222 0.088889 0.888889 0.000000 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.466667 0.266667 0.266667 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GCGGGAAV MEME-1 regular expression -------------------------------------------------------------------------------- GCGGGAA[ACG] -------------------------------------------------------------------------------- Time 5.29 secs. ******************************************************************************** ******************************************************************************** MOTIF TTCCCGCC MEME-2 width = 8 sites = 53 llr = 439 E-value = 1.3e-017 ******************************************************************************** -------------------------------------------------------------------------------- Motif TTCCCGCC MEME-2 Description -------------------------------------------------------------------------------- Simplified A :::::::: pos.-specific C 1:a99:a8 probability G :::1:a:2 matrix T 9a::1::: bits 3.0 * 2.7 * 2.4 ** 2.1 ** Relative 1.8 ** Entropy 1.5 ** * (11.9 bits) 1.2 *** ** 0.9 ******** 0.6 ******** 0.3 ******** 0.0 -------- Multilevel TTCCCGCC consensus sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTCCCGCC MEME-2 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr3:196696851-196696931 40 4.52e-05 CCGCTGGAGC TTcccgcc cgcgccgccg chr19:19285953-19286033 48 4.52e-05 GAGGCTGAAC TTCCCGCC AACGCTTTGC chrX:153707392-153707472 17 4.52e-05 GCGTGGTCAG TTCCCGCC AAGCGGCCCT chr12:1059071-1059151 17 4.52e-05 TGCCTCCTAC TTCCCGCC AGCTTCCCTC chr2:132250551-132250631 50 4.52e-05 AGAAGCGCTT TTCCCGCC CGGCCGCGGG chr1:175403566-175403646 55 4.52e-05 CACTGTGACC TTCCCGCC ATTTGCCCTG chr19:591681-591761 33 4.52e-05 GCCTGCGGTT TTCCCGCC TGTCTCTCCT chr11:74303585-74303665 50 4.52e-05 GCAAAGACGT TTCCCGCC GGCGGGAGCT chr1:32170905-32170985 2 4.52e-05 T TTCCCGCC TCCAGACCCA chr1:155197501-155197581 28 4.52e-05 TCTCAGCGCT TTCCCGCC AGCACACCCT chr2:48010233-48010313 55 4.52e-05 CCCCCCAGAT TTCCCGCC AGCAGGAGCC chr19:797868-797948 1 4.52e-05 . TTCCCGCC TCCCGTCCGC chr11:9595067-9595147 19 4.52e-05 AGCCAGCGGG TTCCCGCC AAAATCGCGT chr1:180502805-180502885 55 4.52e-05 CATCGCCATT TTCCCGCC TGCCTTCTCT chr17:60501134-60501214 38 4.52e-05 GCCACCCTTT TTCCCGCC CAGACTCCGC chr16:19897683-19897763 38 4.52e-05 CCAAAGTGTG TTCCCGCC AGACTGCGCA chr2:27309460-27309540 51 4.52e-05 GCGCTCTGCG TTCCCGCC ACGTGAGGCT chr3:6549395-6549475 36 4.52e-05 gccccccggg ttcccgcc attctcccgc chr15:66914607-66914687 68 4.52e-05 ccttcccgcc ttcccgcc ttccc chr16:85722530-85722610 55 4.52e-05 GGCCGCCGTT TTCCCGCC ACGGCGAGAG chr6:37137547-37137627 55 4.52e-05 CGCCTTTTCC TTCCCGCC ACGTCGTGGC chr7:2710754-2710834 27 4.52e-05 CTTTCTGCAG TTCCCGCC GTGCTGGGCG chr10:79606578-79606658 51 4.52e-05 CTGCAGCGGC TTCCCGCC TTCCCAGCTC chr19:34262589-34262669 13 4.52e-05 AGGCCACCTA TTCCCGCC ACCCTCTCCC chr6:140469609-140469689 11 4.52e-05 gcagccccgg ttcccgcc cgcgcctctc chr11:75863332-75863412 18 4.52e-05 GCGGGCCCCG TTCCCGCC ATTCCTTCCT chr2:177005428-177005508 33 9.02e-05 CGCTCCTCCC TTCCCGCG CACTCTACCT chr21:34960941-34961021 48 9.02e-05 CTACAGAGAC TTcccgcg cgcgccgggc chr2:8825988-8826068 21 9.02e-05 CGGAGGCGAC TTCCCGCG GCGCCAGCCG chr19:16222141-16222221 14 9.02e-05 CTACCTTGCT TTCCCGCG CTCGCCTCGG chr17:33446818-33446898 13 9.02e-05 TCCGCCGGGA TTCCCGCG CCCAGAGCCC chr6:34122628-34122708 9 9.02e-05 AGCCTCGA TTCCCGCG CGCCCGAGCG chr7:155137674-155137754 5 9.02e-05 AAGC TTCCCGCG CGGGGACTGA chr16:3033778-3033858 2 9.02e-05 G TTCCCGCG AGTCCCACCC chr18:8609356-8609436 60 1.06e-04 gcgccTGCGC TTCCTGCC CCTCCTCGTC chr15:65579199-65579279 19 1.06e-04 CGCGCGCGCC TTCCTGCC CCGCCTCCCG chr11:9779798-9779878 46 1.22e-04 CGCCCGCAGG TTCCAGCC CCGACCCGGG chr3:58477659-58477739 5 1.22e-04 TGGC TTCCAGCC CGCGCTGCCG chr2:136634044-136634124 49 1.67e-04 AGCTGGAGAT TTCGCGCC AAACCTGACC chr22:35795921-35796001 14 1.67e-04 AGCCAGAAGT TTCGCGCC AAATTGTTCC chr11:69458182-69458262 53 1.67e-04 TCCCACCGCG TTCGCGCC CCGCGGTGTG chr2:20850875-20850955 70 1.67e-04 GGCCGCGCAG TTCGCGCC TGT chr16:30662745-30662825 52 1.67e-04 GGGGCGCCCT TTCGCGCC CCAGGGCTGC chr1:91966527-91966607 55 1.83e-04 GACTTCGGTT TTCTCGCC GTGCAGTTCC chr11:3876262-3876342 12 2.14e-04 TTTGCTGATT TTCCCACC AGGGGCCGCT chr1:33177945-33178025 35 2.14e-04 ggggTTGTCT TTTccgcc gcagccgcgc chr17:42287881-42287961 36 3.43e-04 AGCCCAGGCG CTCCCGCC GGCGGGCAGA chrX:129194575-129194655 49 3.43e-04 CCGGGCCACT CTCCCGCC ATCGCTGGCT chr17:79075649-79075729 44 3.43e-04 GAGCGCAGGC CTCCCGCC TGCTAGACCC chr12:50101425-50101505 41 3.43e-04 ATCACAGCGC CTCCCGCC CTTGACGGCC chr16:89641184-89641264 70 3.43e-04 CCTGTGCTGC CTCCCGCC GGC chr6:33739409-33739489 73 3.43e-04 CACTGCGCCT CTCCCGCC chr17:79196802-79196882 12 3.59e-04 CGGCCCGCCT TTCCTGCG CGCGCCGACT -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTCCCGCC MEME-2 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr3:196696851-196696931 4.5e-05 39_[+2]_33 chr19:19285953-19286033 4.5e-05 47_[+2]_25 chrX:153707392-153707472 4.5e-05 16_[+2]_56 chr12:1059071-1059151 4.5e-05 16_[+2]_56 chr2:132250551-132250631 4.5e-05 49_[+2]_23 chr1:175403566-175403646 4.5e-05 54_[+2]_18 chr19:591681-591761 4.5e-05 32_[+2]_40 chr11:74303585-74303665 4.5e-05 49_[+2]_23 chr1:32170905-32170985 4.5e-05 1_[+2]_71 chr1:155197501-155197581 4.5e-05 27_[+2]_45 chr2:48010233-48010313 4.5e-05 54_[+2]_18 chr19:797868-797948 4.5e-05 [+2]_72 chr11:9595067-9595147 4.5e-05 18_[+2]_54 chr1:180502805-180502885 4.5e-05 54_[+2]_18 chr17:60501134-60501214 4.5e-05 37_[+2]_35 chr16:19897683-19897763 4.5e-05 37_[+2]_35 chr2:27309460-27309540 4.5e-05 50_[+2]_22 chr3:6549395-6549475 4.5e-05 35_[+2]_37 chr15:66914607-66914687 4.5e-05 67_[+2]_5 chr16:85722530-85722610 4.5e-05 54_[+2]_18 chr6:37137547-37137627 4.5e-05 54_[+2]_18 chr7:2710754-2710834 4.5e-05 26_[+2]_46 chr10:79606578-79606658 4.5e-05 50_[+2]_22 chr19:34262589-34262669 4.5e-05 12_[+2]_60 chr6:140469609-140469689 4.5e-05 10_[+2]_62 chr11:75863332-75863412 4.5e-05 17_[+2]_55 chr2:177005428-177005508 9e-05 32_[+2]_40 chr21:34960941-34961021 9e-05 47_[+2]_25 chr2:8825988-8826068 9e-05 20_[+2]_52 chr19:16222141-16222221 9e-05 13_[+2]_59 chr17:33446818-33446898 9e-05 12_[+2]_60 chr6:34122628-34122708 9e-05 8_[+2]_64 chr7:155137674-155137754 9e-05 4_[+2]_68 chr16:3033778-3033858 9e-05 1_[+2]_71 chr18:8609356-8609436 0.00011 59_[+2]_13 chr15:65579199-65579279 0.00011 18_[+2]_54 chr11:9779798-9779878 0.00012 45_[+2]_27 chr3:58477659-58477739 0.00012 4_[+2]_68 chr2:136634044-136634124 0.00017 48_[+2]_24 chr22:35795921-35796001 0.00017 13_[+2]_59 chr11:69458182-69458262 0.00017 52_[+2]_20 chr2:20850875-20850955 0.00017 69_[+2]_3 chr16:30662745-30662825 0.00017 51_[+2]_21 chr1:91966527-91966607 0.00018 54_[+2]_18 chr11:3876262-3876342 0.00021 11_[+2]_61 chr1:33177945-33178025 0.00021 34_[+2]_38 chr17:42287881-42287961 0.00034 35_[+2]_37 chrX:129194575-129194655 0.00034 48_[+2]_24 chr17:79075649-79075729 0.00034 43_[+2]_29 chr12:50101425-50101505 0.00034 40_[+2]_32 chr16:89641184-89641264 0.00034 69_[+2]_3 chr6:33739409-33739489 0.00034 72_[+2] chr17:79196802-79196882 0.00036 11_[+2]_61 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTCCCGCC MEME-2 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF TTCCCGCC width=8 seqs=53 chr3:196696851-196696931 ( 40) TTCCCGCC 1 chr19:19285953-19286033 ( 48) TTCCCGCC 1 chrX:153707392-153707472 ( 17) TTCCCGCC 1 chr12:1059071-1059151 ( 17) TTCCCGCC 1 chr2:132250551-132250631 ( 50) TTCCCGCC 1 chr1:175403566-175403646 ( 55) TTCCCGCC 1 chr19:591681-591761 ( 33) TTCCCGCC 1 chr11:74303585-74303665 ( 50) TTCCCGCC 1 chr1:32170905-32170985 ( 2) TTCCCGCC 1 chr1:155197501-155197581 ( 28) TTCCCGCC 1 chr2:48010233-48010313 ( 55) TTCCCGCC 1 chr19:797868-797948 ( 1) TTCCCGCC 1 chr11:9595067-9595147 ( 19) TTCCCGCC 1 chr1:180502805-180502885 ( 55) TTCCCGCC 1 chr17:60501134-60501214 ( 38) TTCCCGCC 1 chr16:19897683-19897763 ( 38) TTCCCGCC 1 chr2:27309460-27309540 ( 51) TTCCCGCC 1 chr3:6549395-6549475 ( 36) TTCCCGCC 1 chr15:66914607-66914687 ( 68) TTCCCGCC 1 chr16:85722530-85722610 ( 55) TTCCCGCC 1 chr6:37137547-37137627 ( 55) TTCCCGCC 1 chr7:2710754-2710834 ( 27) TTCCCGCC 1 chr10:79606578-79606658 ( 51) TTCCCGCC 1 chr19:34262589-34262669 ( 13) TTCCCGCC 1 chr6:140469609-140469689 ( 11) TTCCCGCC 1 chr11:75863332-75863412 ( 18) TTCCCGCC 1 chr2:177005428-177005508 ( 33) TTCCCGCG 1 chr21:34960941-34961021 ( 48) TTCCCGCG 1 chr2:8825988-8826068 ( 21) TTCCCGCG 1 chr19:16222141-16222221 ( 14) TTCCCGCG 1 chr17:33446818-33446898 ( 13) TTCCCGCG 1 chr6:34122628-34122708 ( 9) TTCCCGCG 1 chr7:155137674-155137754 ( 5) TTCCCGCG 1 chr16:3033778-3033858 ( 2) TTCCCGCG 1 chr18:8609356-8609436 ( 60) TTCCTGCC 1 chr15:65579199-65579279 ( 19) TTCCTGCC 1 chr11:9779798-9779878 ( 46) TTCCAGCC 1 chr3:58477659-58477739 ( 5) TTCCAGCC 1 chr2:136634044-136634124 ( 49) TTCGCGCC 1 chr22:35795921-35796001 ( 14) TTCGCGCC 1 chr11:69458182-69458262 ( 53) TTCGCGCC 1 chr2:20850875-20850955 ( 70) TTCGCGCC 1 chr16:30662745-30662825 ( 52) TTCGCGCC 1 chr1:91966527-91966607 ( 55) TTCTCGCC 1 chr11:3876262-3876342 ( 12) TTCCCACC 1 chr1:33177945-33178025 ( 35) TTTCCGCC 1 chr17:42287881-42287961 ( 36) CTCCCGCC 1 chrX:129194575-129194655 ( 49) CTCCCGCC 1 chr17:79075649-79075729 ( 44) CTCCCGCC 1 chr12:50101425-50101505 ( 41) CTCCCGCC 1 chr16:89641184-89641264 ( 70) CTCCCGCC 1 chr6:33739409-33739489 ( 73) CTCCCGCC 1 chr17:79196802-79196882 ( 12) TTCCTGCG 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTCCCGCC MEME-2 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 8.97483 E= 1.3e-017 -1237 -171 -1237 276 -1237 -1237 -1237 293 -1237 140 -1237 -279 -1237 125 -197 -279 -176 129 -1237 -121 -276 -1237 141 -1237 -1237 143 -1237 -1237 -1237 116 -112 -1237 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTCCCGCC MEME-2 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 53 E= 1.3e-017 0.000000 0.113208 0.000000 0.886792 0.000000 0.000000 0.000000 1.000000 0.000000 0.981132 0.000000 0.018868 0.000000 0.886792 0.094340 0.018868 0.037736 0.905660 0.000000 0.056604 0.018868 0.000000 0.981132 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.830189 0.169811 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTCCCGCC MEME-2 regular expression -------------------------------------------------------------------------------- TTCCCGCC -------------------------------------------------------------------------------- Time 9.11 secs. ******************************************************************************** ******************************************************************************** MOTIF YGCCCCCT MEME-3 width = 8 sites = 44 llr = 353 E-value = 6.5e-003 ******************************************************************************** -------------------------------------------------------------------------------- Motif YGCCCCCT MEME-3 Description -------------------------------------------------------------------------------- Simplified A ::::3::: pos.-specific C 6:aa78a: probability G :a:::::: matrix T 4::::2:a bits 3.0 * 2.7 * 2.4 * 2.1 * Relative 1.8 * Entropy 1.5 ** ** (11.6 bits) 1.2 *** ** 0.9 ******** 0.6 ******** 0.3 ******** 0.0 -------- Multilevel CGCCCCCT consensus T AT sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YGCCCCCT MEME-3 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr19:982824-982904 54 1.56e-05 GGCTCGCGCC TGCCACCT GGCGGCCAGC chr5:139348485-139348565 27 1.56e-05 CAGCCTGCCC TGCCACCT GGTGGAGAGA chr1:26490830-26490910 27 1.56e-05 CTGCTGCTGC TGCCACCT GCTGGCGAAC chr1:12719098-12719178 69 1.56e-05 TAGGATGTAC TGCCACCT GGTG chr15:64445882-64445962 37 6.08e-05 TGGCCCCTGC TGCCCCCT AGTGGCCATA chr3:196696851-196696931 67 6.08e-05 ggcccgACGC TGCCCCCT GGCGGG chr12:1059071-1059151 59 6.08e-05 GGATCTCTGC TGCCCCCT GGTGGGCCTG chr22:23470728-23470808 62 6.08e-05 AGTCCTGGGG TGCCCCCT CCTGGTTACT chr2:10575183-10575263 57 6.08e-05 GGGGTGCTGC TGCCCCCT GGTGTCCATA chr16:1979819-1979899 46 6.08e-05 CGAGCGAGCG TGCCCCCT GCTGGTCAGT chr2:20850875-20850955 43 6.08e-05 TGCCCTGGCC TGCCCCCT GGTGGCAGCG chr14:105512173-10551225 20 6.08e-05 TTGCAGCTGC TGCCCCCT GGCGGCCGCG chr22:23226291-23226371 20 6.08e-05 TGGTCTCTTC TGCCCCCT ACTGGATTCT chr19:10982043-10982123 45 8.22e-05 CCCCACGGGG TGCCCTCT CGTTCGCTCG chr22:20273396-20273476 30 8.22e-05 GGCCCTCTGC TGCCCTCT GCCGGCCGCC chr11:76510391-76510471 67 1.26e-04 CGGCCCGCAG CGCCACCT CGTGCT chrX:129194575-129194655 73 1.26e-04 GGCTCGACAG CGCCACCT chr4:57410881-57410961 48 1.26e-04 CCGTCTGGAG CGCCACCT GGCCCGAGGG chr12:102224701-10222478 57 1.26e-04 gggTCTCCAG CGCCACCT GGAGGACGGA chr2:8825988-8826068 69 1.26e-04 GGAGCCCGGG CGCCACCT GCTG chr19:18272196-18272276 35 1.26e-04 GGGCCCTGGG CGCCACCT TTGGgccgct chr19:19285953-19286033 72 2.55e-04 TTGCCTCTTG CGCCCCCT G chr19:41140554-41140634 47 2.55e-04 AAGCCGGCTG CGCCCCCT AGTGGCCGAT chr20:30200773-30200853 1 2.55e-04 . CGCCCCCT CCCGGGCAGA chr10:73533302-73533382 29 2.55e-04 TCCAGGCACC CGCCCCCT TCGCGCAGCG chr7:43878596-43878676 30 2.55e-04 GCGGCTCGCA CGCCCCCT GCTGGTCATC chr7:47294139-47294219 53 2.55e-04 ATGGCGCGCG CGCCCCCT GCCGGCCACA chr1:211307497-211307577 66 2.55e-04 GGGCCGGCGG CGCCCCCT ACCGGGC chr10:49864444-49864524 29 2.55e-04 TGGTGCACGG CGCCCCCT GGCGGGCCTC chr16:67189384-67189464 43 2.55e-04 CGGCGCGCAG CGCCCCCT CGCGGTAGGC chr2:243153819-243153899 22 2.55e-04 tgctgtccag cgccccct gctggcgccg chr1:181999200-181999280 19 2.55e-04 GGTCAGGCGC CGCCCCCT TGTGGTCTCG chr19:14185985-14186065 73 2.55e-04 CAGGTCCTAC CGCCCCCT chr12:7126213-7126293 63 2.55e-04 GCCTTTCGCG CGCCCCCT AACGGCGCCT chr18:45275647-45275727 72 2.55e-04 GACGCTCTGG CGCCCCCT G chr19:34262589-34262669 54 2.70e-04 GGGAGGACCG CGCCATCT TGTGGCCGAA chr10:44806611-44806691 17 3.16e-04 GCTCGGAGCG CGCCCTCT GCTGGACCGG chr6:41754310-41754390 21 3.16e-04 GGGAGGCGGA CGCCCTCT GGTGGAGGCG chr19:50184076-50184156 52 3.16e-04 TGGTCTCTGC CGCCCTCT AGTGACCGGC chr6:40995861-40995941 28 3.16e-04 TGGGCTCCTG CGCCCTCT GCCGGCCAGG chr11:93276549-93276629 33 3.16e-04 CAGCGCCAGG CGCCCTCT GCCGCCGGGA chr6:157695857-157695937 43 3.16e-04 GCGCCTCGGC CGCCCTCT GCTGGGCGAA chr1:226309302-226309382 33 3.16e-04 AGCAGCCGGG CGCCCTCT GGTGGCCGCC chr2:130939167-130939247 54 3.21e-04 GGAAAAGCGC TTCCACCT CTTTGGGCCG -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YGCCCCCT MEME-3 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr19:982824-982904 1.6e-05 53_[+3]_19 chr5:139348485-139348565 1.6e-05 26_[+3]_46 chr1:26490830-26490910 1.6e-05 26_[+3]_46 chr1:12719098-12719178 1.6e-05 68_[+3]_4 chr15:64445882-64445962 6.1e-05 36_[+3]_36 chr3:196696851-196696931 6.1e-05 66_[+3]_6 chr12:1059071-1059151 6.1e-05 58_[+3]_14 chr22:23470728-23470808 6.1e-05 61_[+3]_11 chr2:10575183-10575263 6.1e-05 56_[+3]_16 chr16:1979819-1979899 6.1e-05 45_[+3]_27 chr2:20850875-20850955 6.1e-05 42_[+3]_30 chr14:105512173-10551225 6.1e-05 19_[+3]_53 chr22:23226291-23226371 6.1e-05 19_[+3]_53 chr19:10982043-10982123 8.2e-05 44_[+3]_28 chr22:20273396-20273476 8.2e-05 29_[+3]_43 chr11:76510391-76510471 0.00013 66_[+3]_6 chrX:129194575-129194655 0.00013 72_[+3] chr4:57410881-57410961 0.00013 47_[+3]_25 chr12:102224701-10222478 0.00013 56_[+3]_16 chr2:8825988-8826068 0.00013 68_[+3]_4 chr19:18272196-18272276 0.00013 34_[+3]_38 chr19:19285953-19286033 0.00025 71_[+3]_1 chr19:41140554-41140634 0.00025 46_[+3]_26 chr20:30200773-30200853 0.00025 [+3]_72 chr10:73533302-73533382 0.00025 28_[+3]_44 chr7:43878596-43878676 0.00025 29_[+3]_43 chr7:47294139-47294219 0.00025 52_[+3]_20 chr1:211307497-211307577 0.00025 65_[+3]_7 chr10:49864444-49864524 0.00025 28_[+3]_44 chr16:67189384-67189464 0.00025 42_[+3]_30 chr2:243153819-243153899 0.00025 21_[+3]_51 chr1:181999200-181999280 0.00025 18_[+3]_54 chr19:14185985-14186065 0.00025 72_[+3] chr12:7126213-7126293 0.00025 62_[+3]_10 chr18:45275647-45275727 0.00025 71_[+3]_1 chr19:34262589-34262669 0.00027 53_[+3]_19 chr10:44806611-44806691 0.00032 16_[+3]_56 chr6:41754310-41754390 0.00032 20_[+3]_52 chr19:50184076-50184156 0.00032 51_[+3]_21 chr6:40995861-40995941 0.00032 27_[+3]_45 chr11:93276549-93276629 0.00032 32_[+3]_40 chr6:157695857-157695937 0.00032 42_[+3]_30 chr1:226309302-226309382 0.00032 32_[+3]_40 chr2:130939167-130939247 0.00032 53_[+3]_19 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YGCCCCCT MEME-3 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF YGCCCCCT width=8 seqs=44 chr19:982824-982904 ( 54) TGCCACCT 1 chr5:139348485-139348565 ( 27) TGCCACCT 1 chr1:26490830-26490910 ( 27) TGCCACCT 1 chr1:12719098-12719178 ( 69) TGCCACCT 1 chr15:64445882-64445962 ( 37) TGCCCCCT 1 chr3:196696851-196696931 ( 67) TGCCCCCT 1 chr12:1059071-1059151 ( 59) TGCCCCCT 1 chr22:23470728-23470808 ( 62) TGCCCCCT 1 chr2:10575183-10575263 ( 57) TGCCCCCT 1 chr16:1979819-1979899 ( 46) TGCCCCCT 1 chr2:20850875-20850955 ( 43) TGCCCCCT 1 chr14:105512173-10551225 ( 20) TGCCCCCT 1 chr22:23226291-23226371 ( 20) TGCCCCCT 1 chr19:10982043-10982123 ( 45) TGCCCTCT 1 chr22:20273396-20273476 ( 30) TGCCCTCT 1 chr11:76510391-76510471 ( 67) CGCCACCT 1 chrX:129194575-129194655 ( 73) CGCCACCT 1 chr4:57410881-57410961 ( 48) CGCCACCT 1 chr12:102224701-10222478 ( 57) CGCCACCT 1 chr2:8825988-8826068 ( 69) CGCCACCT 1 chr19:18272196-18272276 ( 35) CGCCACCT 1 chr19:19285953-19286033 ( 72) CGCCCCCT 1 chr19:41140554-41140634 ( 47) CGCCCCCT 1 chr20:30200773-30200853 ( 1) CGCCCCCT 1 chr10:73533302-73533382 ( 29) CGCCCCCT 1 chr7:43878596-43878676 ( 30) CGCCCCCT 1 chr7:47294139-47294219 ( 53) CGCCCCCT 1 chr1:211307497-211307577 ( 66) CGCCCCCT 1 chr10:49864444-49864524 ( 29) CGCCCCCT 1 chr16:67189384-67189464 ( 43) CGCCCCCT 1 chr2:243153819-243153899 ( 22) CGCCCCCT 1 chr1:181999200-181999280 ( 19) CGCCCCCT 1 chr19:14185985-14186065 ( 73) CGCCCCCT 1 chr12:7126213-7126293 ( 63) CGCCCCCT 1 chr18:45275647-45275727 ( 72) CGCCCCCT 1 chr19:34262589-34262669 ( 54) CGCCATCT 1 chr10:44806611-44806691 ( 17) CGCCCTCT 1 chr6:41754310-41754390 ( 21) CGCCCTCT 1 chr19:50184076-50184156 ( 52) CGCCCTCT 1 chr6:40995861-40995941 ( 28) CGCCCTCT 1 chr11:93276549-93276629 ( 33) CGCCCTCT 1 chr6:157695857-157695937 ( 43) CGCCCTCT 1 chr1:226309302-226309382 ( 33) CGCCCTCT 1 chr2:130939167-130939247 ( 54) TTCCACCT 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YGCCCCCT MEME-3 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 9.04855 E= 6.5e-003 -1210 78 -1210 147 -1210 -1210 140 -253 -1210 143 -1210 -1210 -1210 143 -1210 -1210 109 97 -1210 -1210 -1210 106 -1210 79 -1210 143 -1210 -1210 -1210 -1210 -1210 293 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YGCCCCCT MEME-3 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 44 E= 6.5e-003 0.000000 0.636364 0.000000 0.363636 0.000000 0.000000 0.977273 0.022727 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.272727 0.727273 0.000000 0.000000 0.000000 0.772727 0.000000 0.227273 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YGCCCCCT MEME-3 regular expression -------------------------------------------------------------------------------- [CT]GCC[CA][CT]CT -------------------------------------------------------------------------------- Time 12.86 secs. ******************************************************************************** ******************************************************************************** MOTIF AGMAAAAA MEME-4 width = 8 sites = 10 llr = 107 E-value = 3.3e+001 ******************************************************************************** -------------------------------------------------------------------------------- Motif AGMAAAAA MEME-4 Description -------------------------------------------------------------------------------- Simplified A 6:57a9a7 pos.-specific C ::3::1:: probability G 2a23:::: matrix T 2::::::3 bits 3.0 * * 2.7 * * 2.4 *** 2.1 **** Relative 1.8 **** Entropy 1.5 * ***** (15.4 bits) 1.2 ** ***** 0.9 ** ***** 0.6 ******** 0.3 ******** 0.0 -------- Multilevel AGAAAAAA consensus G CG T sequence T G -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AGMAAAAA MEME-4 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr5:150827041-150827121 52 2.08e-07 GAGCTCAGTG AGAAAAAA GGCGCGGCCG chr1:12719098-12719178 1 4.21e-07 . AGAAAAAT TTGCCCATAG chr22:23027568-23027648 11 2.66e-06 GTCACCTGGA AGGAAAAA GCTCCTGGGC chr22:50946647-50946727 26 3.88e-06 GGGCGGGAAC AGCAAAAT GGCGCCAGAA chr10:103911793-10391187 36 6.35e-06 ACCGCTGCTC TGAGAAAA GGTACCTCCC chr10:79606578-79606658 69 8.19e-06 TTCCCAGCTC AGAAACAA ACTC chr19:48867540-48867620 46 9.94e-06 GCTGTGGAGG AGCGAAAA GGCGGGAAAA chr22:23112872-23112952 9 1.23e-05 AGTAACCT GGCAAAAA TCCCTGGAAA chr17:79917736-79917816 53 1.53e-05 CTGTGGTCCG TGGAAAAT CCCCACGTTC chr13:37573490-37573570 72 1.71e-05 GTGGCGAGGC GGAGAAAA C -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AGMAAAAA MEME-4 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr5:150827041-150827121 2.1e-07 51_[+4]_21 chr1:12719098-12719178 4.2e-07 [+4]_72 chr22:23027568-23027648 2.7e-06 10_[+4]_62 chr22:50946647-50946727 3.9e-06 25_[+4]_47 chr10:103911793-10391187 6.4e-06 35_[+4]_37 chr10:79606578-79606658 8.2e-06 68_[+4]_4 chr19:48867540-48867620 9.9e-06 45_[+4]_27 chr22:23112872-23112952 1.2e-05 8_[+4]_64 chr17:79917736-79917816 1.5e-05 52_[+4]_20 chr13:37573490-37573570 1.7e-05 71_[+4]_1 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AGMAAAAA MEME-4 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF AGMAAAAA width=8 seqs=10 chr5:150827041-150827121 ( 52) AGAAAAAA 1 chr1:12719098-12719178 ( 1) AGAAAAAT 1 chr22:23027568-23027648 ( 11) AGGAAAAA 1 chr22:50946647-50946727 ( 26) AGCAAAAT 1 chr10:103911793-10391187 ( 36) TGAGAAAA 1 chr10:79606578-79606658 ( 69) AGAAACAA 1 chr19:48867540-48867620 ( 46) AGCGAAAA 1 chr22:23112872-23112952 ( 9) GGCAAAAA 1 chr17:79917736-79917816 ( 53) TGGAAAAT 1 chr13:37573490-37573570 ( 72) GGAGAAAA 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AGMAAAAA MEME-4 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 12.3073 E= 3.3e+001 223 -997 -88 61 -997 -997 144 -997 197 -31 -88 -997 245 -997 -30 -997 297 -997 -997 -997 281 -189 -997 -997 297 -997 -997 -997 245 -997 -997 119 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AGMAAAAA MEME-4 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 10 E= 3.3e+001 0.600000 0.000000 0.200000 0.200000 0.000000 0.000000 1.000000 0.000000 0.500000 0.300000 0.200000 0.000000 0.700000 0.000000 0.300000 0.000000 1.000000 0.000000 0.000000 0.000000 0.900000 0.100000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.700000 0.000000 0.000000 0.300000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AGMAAAAA MEME-4 regular expression -------------------------------------------------------------------------------- [AGT]G[ACG][AG]AAA[AT] -------------------------------------------------------------------------------- Time 16.56 secs. ******************************************************************************** ******************************************************************************** MOTIF AGGGGGCG MEME-5 width = 8 sites = 52 llr = 389 E-value = 2.1e+002 ******************************************************************************** -------------------------------------------------------------------------------- Motif AGGGGGCG MEME-5 Description -------------------------------------------------------------------------------- Simplified A a:312:12 pos.-specific C ::::::9: probability G :a778a:8 matrix T :::2:::: bits 3.0 * 2.7 * 2.4 * 2.1 * Relative 1.8 * Entropy 1.5 ** * (10.8 bits) 1.2 ** ** 0.9 *** **** 0.6 ******** 0.3 ******** 0.0 -------- Multilevel AGGGGGCG consensus A A sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AGGGGGCG MEME-5 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr11:46260806-46260886 64 4.23e-05 CGCGGCCGGC AGAGGGCG CTGCCGCAC chr1:114889270-114889350 65 4.23e-05 AGTGTCCATT AGAGGGCG CCAGCGCG chr1:17033975-17034055 29 4.23e-05 CGGTGCCAGC AGAgggcg cgcgccccca chr1:223307166-223307246 19 4.23e-05 AGAGACCAGC AGAGGGCG CAAAAGGGGC chr19:13076319-13076399 19 4.23e-05 AGCCGCCGCC AGAGGGCG AGCACGCCGC chr1:225662783-225662863 14 4.23e-05 GTCGGCCGGC AGAGGGCG CTGCGCACCC chr17:60501134-60501214 66 4.23e-05 GTCTTCTGAA AGAGGGCG TGGTCCG chr11:2554134-2554214 54 4.23e-05 TGTAGACGCC AGAGGGCG CTCGTGCTAC chr15:41234158-41234238 71 4.23e-05 gcccggcACT AGAGGGCG CT chr9:133336721-133336801 12 4.23e-05 TGTGGCCACC AGAGGGCG CCAGAGGCTT chr17:42287881-42287961 1 1.64e-04 . AGGGGGCG CGCGCTCCCC chr22:21457229-21457309 28 1.64e-04 CGTGACCATC AGGGGGCG CCCCAACCAC chr1:211688924-211689004 15 1.64e-04 CACAATCAGC AGGGGGCG CCCGTCCCGA chr11:67033758-67033838 53 1.64e-04 CGCGGCCTCC AGGGGGCG CCGTCGCCCG chr12:56583427-56583507 73 1.64e-04 CGCTTCCTGG AGGGGGCG chr19:48867540-48867620 7 1.64e-04 AGAGGG AGGGGGCG GGACTTGGGC chr17:47653098-47653178 54 1.64e-04 ggcgtccgcc agggggcg cgccgcgacg chr3:58477659-58477739 25 1.64e-04 CGCTGCCGTT AGGGGGCG CCCGCGCTCG chr2:27309460-27309540 36 1.64e-04 GGCGTCCGCC AGGGGGCG CTCTGCGTTC chr1:805271-805351 35 1.64e-04 GGCTGCCACC AGGGGGCG CGCCCGCGGT chr3:140950571-140950651 42 1.64e-04 cggggtcggc agggggcg ctgccgggcc chr11:46368922-46369002 21 1.64e-04 CGTGCGGCCG AGGGGGCG TGCTCGGCGG chr1:9555453-9555533 19 1.64e-04 TGCGGCCACC AGGGGGCG CAGCAGCGCC chr3:47563726-47563806 40 1.79e-04 CACACCCACC AGAGGGCA GCAGACACTG chr22:23053360-23053440 29 2.21e-04 AGTGGCCACC AGGGGGCA GCAGAGAGTA chr22:22936652-22936732 25 2.21e-04 TGTGGGCACC AGGGGGCA CTGTGACCCC chr6:33739409-33739489 46 2.21e-04 TGTGGCCGGC AGGGGGCA GCCTGCAGCC chr7:50535861-50535941 41 2.51e-04 TCATGCCACC AGAGAGCG CCAAAGACCT chr13:53024820-53024900 23 3.36e-04 TGAGGGACGG AGGGAGCG GCCTGGCAGC chr19:5804097-5804177 62 3.36e-04 CGGCGCCGCC AGGGAGCG CTGTGGGAGC chr17:62915609-62915689 29 3.36e-04 GGACGGGGCG AGGTGGCG CGGCGGCCGC chr12:1905346-1905426 11 3.36e-04 CTTGGCCACC AGGTGGCG CAGTGGCCCC chr6:107435531-107435611 72 3.36e-04 ACGGCCGGGA AGGGAGCG C chr17:79075649-79075729 21 3.36e-04 GCTGCCAGGC AGGGAGCG CTGTGGAGCG chr17:79917736-79917816 5 3.36e-04 CGGG AGGTGGCG CTCGCGGGGC chr1:46269169-46269249 55 3.36e-04 gcgcggccgg aggtggcg ggcgggctcc chr3:196729970-196730050 48 3.36e-04 GCGCGGCTCC AGGTGGCG GGAGGCGGCG chr6:34495136-34495216 67 3.51e-04 GCCAAGATCG AGAAGGCG TACGGG chr22:20144667-20144747 31 4.04e-04 TCTCACCACC AGATGGCA CCATGCCCCT chr11:65547570-65547650 42 4.04e-04 AGGAGCCGGC AGGAGGCG CCCGAGGTGG chr22:35795921-35796001 53 4.04e-04 GGAGCCCGGA AGGAGGCG AGGTCATGCA chr15:56285847-56285927 16 4.04e-04 gaggaagagg aggaggCG CTCCCTCAGC chr11:74303585-74303665 35 4.33e-04 GGGACCTGGG AGGGAGCA AAGACGTTTC chr1:211307497-211307577 39 4.33e-04 GGGTGGGCGG AGGGAGCA GCGGCGCCTG chr11:9779798-9779878 17 4.33e-04 CTTCGCCGCC AGGTGGCA GGCGTGCGCC chr10:79606578-79606658 6 4.33e-04 CCACA AGGTGGCA GCCGCGGGGA chr15:64445882-64445962 59 4.73e-04 GCCATATGCT AGGAGGCA GGCCTGCTGC chr16:67189384-67189464 65 5.09e-04 GTAGGCGCGG AGGAAGCG GCCACAGG chr6:26924704-26924784 67 5.09e-04 ccccgccggc agagggag cccgct chr10:70167032-70167112 64 5.56e-04 gggcggcccc agggggag cggcgcccc chr3:196696851-196696931 1 5.83e-04 . AGGGGGAA GACGGCACCA chr7:84509887-84509967 11 6.22e-04 agaggcgccg agggagag gcgccggcgg -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AGGGGGCG MEME-5 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr11:46260806-46260886 4.2e-05 63_[+5]_9 chr1:114889270-114889350 4.2e-05 64_[+5]_8 chr1:17033975-17034055 4.2e-05 28_[+5]_44 chr1:223307166-223307246 4.2e-05 18_[+5]_54 chr19:13076319-13076399 4.2e-05 18_[+5]_54 chr1:225662783-225662863 4.2e-05 13_[+5]_59 chr17:60501134-60501214 4.2e-05 65_[+5]_7 chr11:2554134-2554214 4.2e-05 53_[+5]_19 chr15:41234158-41234238 4.2e-05 70_[+5]_2 chr9:133336721-133336801 4.2e-05 11_[+5]_61 chr17:42287881-42287961 0.00016 [+5]_72 chr22:21457229-21457309 0.00016 27_[+5]_45 chr1:211688924-211689004 0.00016 14_[+5]_58 chr11:67033758-67033838 0.00016 52_[+5]_20 chr12:56583427-56583507 0.00016 72_[+5] chr19:48867540-48867620 0.00016 6_[+5]_66 chr17:47653098-47653178 0.00016 53_[+5]_19 chr3:58477659-58477739 0.00016 24_[+5]_48 chr2:27309460-27309540 0.00016 35_[+5]_37 chr1:805271-805351 0.00016 34_[+5]_38 chr3:140950571-140950651 0.00016 41_[+5]_31 chr11:46368922-46369002 0.00016 20_[+5]_52 chr1:9555453-9555533 0.00016 18_[+5]_54 chr3:47563726-47563806 0.00018 39_[+5]_33 chr22:23053360-23053440 0.00022 28_[+5]_44 chr22:22936652-22936732 0.00022 24_[+5]_48 chr6:33739409-33739489 0.00022 45_[+5]_27 chr7:50535861-50535941 0.00025 40_[+5]_32 chr13:53024820-53024900 0.00034 22_[+5]_50 chr19:5804097-5804177 0.00034 61_[+5]_11 chr17:62915609-62915689 0.00034 28_[+5]_44 chr12:1905346-1905426 0.00034 10_[+5]_62 chr6:107435531-107435611 0.00034 71_[+5]_1 chr17:79075649-79075729 0.00034 20_[+5]_52 chr17:79917736-79917816 0.00034 4_[+5]_68 chr1:46269169-46269249 0.00034 54_[+5]_18 chr3:196729970-196730050 0.00034 47_[+5]_25 chr6:34495136-34495216 0.00035 66_[+5]_6 chr22:20144667-20144747 0.0004 30_[+5]_42 chr11:65547570-65547650 0.0004 41_[+5]_31 chr22:35795921-35796001 0.0004 52_[+5]_20 chr15:56285847-56285927 0.0004 15_[+5]_57 chr11:74303585-74303665 0.00043 34_[+5]_38 chr1:211307497-211307577 0.00043 38_[+5]_34 chr11:9779798-9779878 0.00043 16_[+5]_56 chr10:79606578-79606658 0.00043 5_[+5]_67 chr15:64445882-64445962 0.00047 58_[+5]_14 chr16:67189384-67189464 0.00051 64_[+5]_8 chr6:26924704-26924784 0.00051 66_[+5]_6 chr10:70167032-70167112 0.00056 63_[+5]_9 chr3:196696851-196696931 0.00058 [+5]_72 chr7:84509887-84509967 0.00062 10_[+5]_62 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AGGGGGCG MEME-5 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF AGGGGGCG width=8 seqs=52 chr11:46260806-46260886 ( 64) AGAGGGCG 1 chr1:114889270-114889350 ( 65) AGAGGGCG 1 chr1:17033975-17034055 ( 29) AGAGGGCG 1 chr1:223307166-223307246 ( 19) AGAGGGCG 1 chr19:13076319-13076399 ( 19) AGAGGGCG 1 chr1:225662783-225662863 ( 14) AGAGGGCG 1 chr17:60501134-60501214 ( 66) AGAGGGCG 1 chr11:2554134-2554214 ( 54) AGAGGGCG 1 chr15:41234158-41234238 ( 71) AGAGGGCG 1 chr9:133336721-133336801 ( 12) AGAGGGCG 1 chr17:42287881-42287961 ( 1) AGGGGGCG 1 chr22:21457229-21457309 ( 28) AGGGGGCG 1 chr1:211688924-211689004 ( 15) AGGGGGCG 1 chr11:67033758-67033838 ( 53) AGGGGGCG 1 chr12:56583427-56583507 ( 73) AGGGGGCG 1 chr19:48867540-48867620 ( 7) AGGGGGCG 1 chr17:47653098-47653178 ( 54) AGGGGGCG 1 chr3:58477659-58477739 ( 25) AGGGGGCG 1 chr2:27309460-27309540 ( 36) AGGGGGCG 1 chr1:805271-805351 ( 35) AGGGGGCG 1 chr3:140950571-140950651 ( 42) AGGGGGCG 1 chr11:46368922-46369002 ( 21) AGGGGGCG 1 chr1:9555453-9555533 ( 19) AGGGGGCG 1 chr3:47563726-47563806 ( 40) AGAGGGCA 1 chr22:23053360-23053440 ( 29) AGGGGGCA 1 chr22:22936652-22936732 ( 25) AGGGGGCA 1 chr6:33739409-33739489 ( 46) AGGGGGCA 1 chr7:50535861-50535941 ( 41) AGAGAGCG 1 chr13:53024820-53024900 ( 23) AGGGAGCG 1 chr19:5804097-5804177 ( 62) AGGGAGCG 1 chr17:62915609-62915689 ( 29) AGGTGGCG 1 chr12:1905346-1905426 ( 11) AGGTGGCG 1 chr6:107435531-107435611 ( 72) AGGGAGCG 1 chr17:79075649-79075729 ( 21) AGGGAGCG 1 chr17:79917736-79917816 ( 5) AGGTGGCG 1 chr1:46269169-46269249 ( 55) AGGTGGCG 1 chr3:196729970-196730050 ( 48) AGGTGGCG 1 chr6:34495136-34495216 ( 67) AGAAGGCG 1 chr22:20144667-20144747 ( 31) AGATGGCA 1 chr11:65547570-65547650 ( 42) AGGAGGCG 1 chr22:35795921-35796001 ( 53) AGGAGGCG 1 chr15:56285847-56285927 ( 16) AGGAGGCG 1 chr11:74303585-74303665 ( 35) AGGGAGCA 1 chr1:211307497-211307577 ( 39) AGGGAGCA 1 chr11:9779798-9779878 ( 17) AGGTGGCA 1 chr10:79606578-79606658 ( 6) AGGTGGCA 1 chr15:64445882-64445962 ( 59) AGGAGGCA 1 chr16:67189384-67189464 ( 65) AGGAAGCG 1 chr6:26924704-26924784 ( 67) AGAGGGAG 1 chr10:70167032-70167112 ( 64) AGGGGGAG 1 chr3:196696851-196696931 ( 1) AGGGGGAA 1 chr7:84509887-84509967 ( 11) AGGGAGAG 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AGGGGGCG MEME-5 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 8.98284 E= 2.1e+002 297 -1234 -1234 -1234 -1234 -1234 144 -1234 117 -1234 94 -1234 -15 -1234 98 23 44 -1234 116 -1234 -1234 -1234 144 -1234 -73 131 -1234 -1234 73 -1234 109 -1234 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AGGGGGCG MEME-5 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 52 E= 2.1e+002 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.288462 0.000000 0.711538 0.000000 0.115385 0.000000 0.730769 0.153846 0.173077 0.000000 0.826923 0.000000 0.000000 0.000000 1.000000 0.000000 0.076923 0.923077 0.000000 0.000000 0.211538 0.000000 0.788462 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AGGGGGCG MEME-5 regular expression -------------------------------------------------------------------------------- AG[GA]GGGC[GA] -------------------------------------------------------------------------------- Time 20.16 secs. ******************************************************************************** ******************************************************************************** SUMMARY OF MOTIFS ******************************************************************************** -------------------------------------------------------------------------------- Combined block diagrams: non-overlapping sites with p-value < 0.0001 -------------------------------------------------------------------------------- SEQUENCE NAME COMBINED P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr8:12458968-12459048 8.16e-01 80 chr9:133336721-133336801 3.58e-02 11_[+5(4.23e-05)]_61 chr5:150036158-150036238 1.40e-02 80 chr20:656289-656369 8.01e-01 80 chr19:46532329-46532409 1.51e-01 80 chr11:75863332-75863412 4.19e-02 17_[+2(4.52e-05)]_55 chr5:176005456-176005536 1.19e-02 22_[+1(9.94e-05)]_50 chr3:196729970-196730050 1.58e-02 69_[+1(9.94e-05)]_3 chr7:54841998-54842078 1.74e-02 65_[+1(1.46e-05)]_7 chr16:3033778-3033858 1.08e-01 1_[+2(9.02e-05)]_71 chr16:66785610-66785690 4.91e-01 80 chr9:33720203-33720283 4.41e-02 13_[+1(9.94e-05)]_59 chr18:45275647-45275727 2.41e-02 80 chr15:41234158-41234238 1.70e-02 7_[+1(9.94e-05)]_55_[+5(4.23e-05)]_\ 2 chr1:9555453-9555533 1.37e-03 46_[+1(1.46e-05)]_26 chr11:46368922-46369002 7.25e-02 80 chr1:46269169-46269249 2.27e-01 80 chr16:50402854-50402934 6.99e-03 62_[+1(1.46e-05)]_10 chr22:20273396-20273476 3.14e-01 29_[+3(8.22e-05)]_43 chr8:143808494-143808574 3.28e-01 80 chr6:140469609-140469689 6.66e-02 10_[+2(4.52e-05)]_62 chr7:155137674-155137754 7.30e-02 4_[+2(9.02e-05)]_68 chr1:208042526-208042606 4.04e-01 80 chr19:18272196-18272276 2.60e-01 80 chr7:50535861-50535941 3.18e-02 80 chr21:33104588-33104668 5.03e-01 80 chr16:30662745-30662825 4.49e-02 80 chr19:34262589-34262669 4.25e-03 12_[+2(4.52e-05)]_60 chr7:149484638-149484718 3.42e-02 25_[+1(1.46e-05)]_47 chr10:79606578-79606658 3.19e-05 50_[+2(4.52e-05)]_10_[+4(8.19e-06)]_\ 4 chr15:44119181-44119261 4.81e-02 16_[+1(9.94e-05)]_56 chr12:7126213-7126293 1.09e-03 35_[+1(9.94e-05)]_37 chr1:29562975-29563055 8.79e-01 80 chr22:20255935-20256015 4.90e-01 80 chr6:33739409-33739489 8.82e-03 80 chr22:18507290-18507370 8.18e-01 80 chr21:37757676-37757756 1.90e-01 11_[+1(9.94e-05)]_61 chr20:49411410-49411490 5.10e-01 80 chr16:88870141-88870221 4.42e-03 20_[+1(1.46e-05)]_4_[+1(9.94e-05)]_\ 40 chr15:48624363-48624443 6.29e-01 80 chr19:46282673-46282753 9.58e-01 80 chr7:2710754-2710834 6.69e-02 26_[+2(4.52e-05)]_46 chr6:34122628-34122708 1.39e-01 8_[+2(9.02e-05)]_64 chr10:46951456-46951536 4.88e-01 80 chr6:34495136-34495216 1.15e-01 80 chr6:37137547-37137627 3.57e-02 54_[+2(4.52e-05)]_18 chr1:226309302-226309382 6.81e-02 80 chr17:33446818-33446898 2.44e-01 12_[+2(9.02e-05)]_60 chr7:100253999-100254079 6.78e-01 80 chr6:157695857-157695937 3.66e-02 80 chr16:85722530-85722610 4.55e-02 54_[+2(4.52e-05)]_18 chr3:140950571-140950651 3.68e-01 80 chr1:937330-937410 4.41e-02 36_[+1(1.46e-05)]_36 chr19:16222141-16222221 5.26e-03 13_[+2(9.02e-05)]_59 chr11:2554134-2554214 9.97e-04 32_[+1(9.94e-05)]_13_[+5(4.23e-05)]_\ 19 chr1:805271-805351 3.79e-02 80 chr12:110318317-11031839 8.99e-01 80 chr15:66914607-66914687 1.92e-01 59_[+2(4.52e-05)]_[+2(4.52e-05)]_5 chr3:6549395-6549475 5.90e-02 35_[+2(4.52e-05)]_37 chr1:12719098-12719178 2.90e-05 [+4(4.21e-07)]_60_[+3(1.56e-05)]_4 chr19:10982043-10982123 5.29e-02 44_[+3(8.22e-05)]_28 chr2:27309460-27309540 7.22e-03 50_[+2(4.52e-05)]_22 chr16:19897683-19897763 1.38e-02 37_[+2(4.52e-05)]_35 chr22:20287369-20287449 5.41e-01 80 chr6:26924704-26924784 1.06e-01 80 chr13:33160502-33160582 7.35e-01 80 chr22:23226291-23226371 3.78e-02 19_[+3(6.08e-05)]_53 chr8:26435184-26435264 5.19e-03 80 chr1:144886724-144886804 1.35e-01 80 chr3:58477659-58477739 1.86e-02 80 chr14:105512173-10551225 1.56e-04 19_[+3(6.08e-05)]_21_[+1(1.46e-05)]_\ 24 chr17:47653098-47653178 1.83e-01 80 chr7:105517155-105517235 6.34e-01 80 chr19:14185985-14186065 2.73e-01 80 chr19:10138487-10138567 4.02e-01 80 chr17:60501134-60501214 1.45e-03 37_[+2(4.52e-05)]_20_[+5(4.23e-05)]_\ 7 chr15:65579199-65579279 2.64e-01 80 chr1:31867658-31867738 5.08e-01 80 chr1:181999200-181999280 2.89e-02 61_[+1(9.94e-05)]_11 chr2:20850875-20850955 1.91e-02 42_[+3(6.08e-05)]_30 chr1:180502805-180502885 2.81e-02 54_[+2(4.52e-05)]_18 chr11:69458182-69458262 3.38e-02 80 chr10:121632313-12163239 1.32e-02 43_[+1(1.46e-05)]_29 chr20:32274168-32274248 4.92e-02 80 chr6:34759758-34759838 3.49e-01 80 chr15:40799366-40799446 2.08e-01 80 chr3:13461865-13461945 2.26e-01 14_[+1(9.94e-05)]_58 chr11:9595067-9595147 8.37e-03 18_[+2(4.52e-05)]_54 chr2:8825988-8826068 8.90e-03 20_[+2(9.02e-05)]_52 chr7:84509887-84509967 5.90e-02 24_[+1(9.94e-05)]_48 chr19:15543570-15543650 5.50e-01 80 chr14:105071189-10507126 2.39e-01 24_[+1(9.94e-05)]_48 chr8:145597558-145597638 3.01e-01 80 chr6:90539464-90539544 8.89e-02 23_[+1(9.94e-05)]_49 chr5:1645114-1645194 3.61e-02 11_[+1(9.94e-05)]_61 chr1:225662783-225662863 2.07e-01 13_[+5(4.23e-05)]_59 chr11:93276549-93276629 6.30e-02 80 chr12:58026939-58027019 4.63e-02 80 chr2:243153819-243153899 3.49e-01 80 chr21:40720819-40720899 2.76e-01 80 chr12:102224701-10222478 4.84e-02 80 chr19:797868-797948 1.64e-01 [+2(4.52e-05)]_72 chr12:54610945-54611025 2.24e-01 80 chr16:89641184-89641264 1.73e-01 80 chr22:19711719-19711799 6.23e-01 80 chr11:111472785-11147286 3.27e-01 80 chr9:129622692-129622772 9.38e-01 80 chr4:57410881-57410961 7.20e-02 80 chr16:1979819-1979899 7.95e-02 45_[+3(6.08e-05)]_27 chr16:3019215-3019295 1.22e-01 62_[+1(9.94e-05)]_10 chr17:34838915-34838995 1.50e-01 80 chr6:40995861-40995941 1.42e-02 80 chr15:56285847-56285927 7.34e-03 80 chr17:79917736-79917816 8.41e-04 52_[+4(1.53e-05)]_20 chr16:57610432-57610512 2.54e-01 80 chr17:43971745-43971825 9.80e-02 80 chr9:132372872-132372952 5.58e-02 33_[+4(5.75e-05)]_39 chr19:48867540-48867620 5.10e-05 45_[+4(9.94e-06)]_1_[+1(1.46e-05)]_\ 18 chr16:67189384-67189464 3.98e-02 80 chr1:33177945-33178025 4.91e-01 80 chr21:34960941-34961021 1.04e-01 47_[+2(9.02e-05)]_25 chr16:89160211-89160291 8.01e-01 80 chr7:100609561-100609641 8.45e-01 80 chr2:48010233-48010313 8.55e-02 54_[+2(4.52e-05)]_18 chr1:26490830-26490910 9.25e-02 26_[+3(1.56e-05)]_46 chr12:27167349-27167429 1.50e-01 80 chr18:8609356-8609436 1.87e-01 80 chr12:50101425-50101505 5.81e-01 80 chr17:79075649-79075729 4.33e-02 80 chr16:11439266-11439346 1.38e-02 20_[+1(1.46e-05)]_52 chr1:155197501-155197581 9.50e-02 27_[+2(4.52e-05)]_45 chr7:75831130-75831210 7.30e-01 80 chr19:1568482-1568562 3.04e-01 20_[+1(9.94e-05)]_52 chr6:35420147-35420227 7.01e-01 80 chr11:9779798-9779878 5.61e-02 80 chr19:47141933-47142013 2.33e-01 80 chr1:32966342-32966422 1.48e-01 80 chr10:49864444-49864524 6.22e-02 80 chr7:154794926-154795006 6.64e-01 80 chr3:12851664-12851744 9.20e-01 80 chr9:140149677-140149757 3.26e-01 80 chr20:5100006-5100086 1.43e-02 80 chr1:211307497-211307577 7.25e-02 80 chr19:13076319-13076399 1.67e-03 18_[+5(4.23e-05)]_41_[+1(1.46e-05)]_\ 5 chr22:22936652-22936732 7.52e-02 80 chr1:91966527-91966607 9.78e-02 80 chr22:35795921-35796001 5.31e-03 80 chr5:139348485-139348565 1.18e-02 26_[+3(1.56e-05)]_46 chr19:34269068-34269148 6.60e-01 80 chr1:23670405-23670485 8.13e-03 12_[+1(1.46e-05)]_60 chr16:30913595-30913675 5.80e-01 80 chr1:36348674-36348754 6.17e-01 80 chr19:14184317-14184397 9.03e-02 80 chr9:139886931-139887011 7.83e-02 80 chr19:50184076-50184156 1.43e-01 80 chr2:136634044-136634124 1.78e-02 80 chr11:3876262-3876342 8.12e-02 80 chr4:1242967-1243047 9.85e-01 80 chr12:56583427-56583507 5.67e-02 80 chr1:32170905-32170985 4.96e-03 1_[+2(4.52e-05)]_71 chr6:107435531-107435611 1.46e-02 37_[+1(9.94e-05)]_35 chr19:982824-982904 2.46e-02 53_[+3(1.56e-05)]_19 chr7:47294139-47294219 1.93e-01 80 chr16:21566307-21566387 4.11e-01 80 chr19:40336347-40336427 3.53e-03 23_[+1(1.46e-05)]_49 chr3:47563726-47563806 1.50e-02 1_[+1(9.94e-05)]_71 chr11:67033758-67033838 3.13e-01 80 chr2:10575183-10575263 1.62e-01 56_[+3(6.08e-05)]_16 chr22:23053360-23053440 2.38e-01 80 chr6:107349337-107349417 2.91e-01 80 chr19:49164342-49164422 1.29e-01 80 chr1:11741170-11741250 9.08e-01 80 chr11:74303585-74303665 6.81e-04 49_[+2(4.52e-05)]_23 chr16:56459473-56459553 5.49e-01 80 chr2:130939167-130939247 4.20e-04 40_[+1(1.46e-05)]_32 chr7:43878596-43878676 4.80e-02 80 chr10:73533302-73533382 2.17e-02 80 chr22:23412266-23412346 5.72e-01 80 chr1:211688924-211689004 2.96e-02 34_[+1(9.94e-05)]_38 chr7:6629577-6629657 3.07e-01 80 chr11:65790033-65790113 1.32e-01 80 chr7:36406850-36406930 3.84e-01 80 chr15:75494343-75494423 5.62e-01 80 chr10:72142414-72142494 6.78e-01 80 chr12:1905346-1905426 3.25e-01 80 chr22:21457229-21457309 5.96e-02 80 chr19:591681-591761 7.99e-02 32_[+2(4.52e-05)]_40 chr1:12679988-12680068 2.05e-01 80 chr2:177005428-177005508 3.19e-02 32_[+2(9.02e-05)]_40 chr10:76995807-76995887 2.64e-01 80 chr7:116166243-116166323 7.38e-01 80 chr17:79196802-79196882 4.31e-01 80 chr17:62915609-62915689 1.05e-01 80 chr2:71222022-71222102 6.36e-01 80 chr1:226150224-226150304 6.21e-01 80 chr1:223307166-223307246 1.77e-02 18_[+5(4.23e-05)]_54 chr3:32823079-32823159 6.45e-01 80 chr6:41754310-41754390 1.64e-01 80 chr1:212606148-212606228 1.44e-01 80 chr1:175403566-175403646 7.90e-02 54_[+2(4.52e-05)]_18 chr11:32914109-32914189 1.48e-01 22_[+1(9.94e-05)]_50 chr2:132250551-132250631 1.95e-02 49_[+2(4.52e-05)]_23 chr10:72968935-72969015 2.62e-01 80 chr9:134615541-134615621 5.27e-02 80 chr11:65547570-65547650 3.66e-01 80 chr22:23470728-23470808 2.09e-02 61_[+3(6.08e-05)]_11 chr13:37573490-37573570 3.48e-03 71_[+4(1.71e-05)]_1 chr19:1240355-1240435 5.21e-01 80 chr7:152133864-152133944 4.02e-01 80 chrX:129194575-129194655 5.17e-02 80 chr22:23052339-23052419 2.55e-01 80 chr10:44806611-44806691 2.83e-01 80 chr8:145669615-145669695 5.61e-02 80 chr3:196439233-196439313 6.33e-01 80 chr19:5804097-5804177 3.68e-01 80 chr5:150827041-150827121 6.02e-04 51_[+4(2.08e-07)]_21 chr12:1059071-1059151 1.38e-02 16_[+2(4.52e-05)]_34_[+3(6.08e-05)]_\ 14 chr1:17033975-17034055 5.57e-02 28_[+5(4.23e-05)]_44 chr20:30200773-30200853 4.34e-03 80 chr19:41140554-41140634 4.24e-01 80 chrX:153707392-153707472 1.45e-01 16_[+2(4.52e-05)]_56 chr12:64237711-64237791 1.75e-01 80 chr1:114889270-114889350 1.48e-01 64_[+5(4.23e-05)]_8 chr7:50517977-50518057 1.55e-01 80 chr12:57146053-57146133 2.03e-01 71_[+1(9.94e-05)]_1 chr19:19285953-19286033 3.00e-03 47_[+2(4.52e-05)]_25 chr22:50946647-50946727 5.15e-04 17_[+1(9.94e-05)]_[+4(3.88e-06)]_47 chr22:23027568-23027648 6.99e-03 10_[+4(2.66e-06)]_62 chr11:129566073-12956615 6.15e-02 24_[+1(9.94e-05)]_48 chr17:42287881-42287961 3.28e-03 80 chr11:798248-798328 5.39e-01 80 chr5:175843561-175843641 8.75e-01 80 chr11:76510391-76510471 2.57e-01 80 chr11:46260806-46260886 1.14e-01 63_[+5(4.23e-05)]_9 chr1:6844896-6844976 7.25e-01 80 chr2:114341549-114341629 8.98e-01 80 chr10:70167032-70167112 1.71e-01 80 chr22:20144667-20144747 3.28e-01 80 chr5:130500301-130500381 2.85e-01 80 chr3:196696851-196696931 4.00e-05 39_[+2(4.52e-05)]_19_[+3(6.08e-05)]_\ 6 chr13:53024820-53024900 3.23e-01 80 chr16:89894973-89895053 9.49e-01 80 chr1:16400127-16400207 8.39e-02 80 chr15:64445882-64445962 2.85e-02 36_[+3(6.08e-05)]_36 chr2:58468528-58468608 4.14e-02 24_[+1(9.94e-05)]_48 chr1:1677863-1677943 1.55e-01 80 chr16:1543424-1543504 6.94e-01 80 chr22:23112872-23112952 2.53e-02 8_[+4(1.23e-05)]_64 chr10:103911793-10391187 3.54e-04 18_[+1(1.46e-05)]_9_[+4(6.35e-06)]_\ 23_[+1(9.94e-05)]_6 chr1:151253798-151253878 1.26e-03 7_[+1(1.46e-05)]_38_[+4(5.75e-05)]_\ 19 -------------------------------------------------------------------------------- ******************************************************************************** ******************************************************************************** Stopped because requested number of motifs (5) found. ******************************************************************************** CPU: c22n05.farnam.hpc.yale.internal ********************************************************************************