******************************************************************************** MEME - Motif discovery tool ******************************************************************************** MEME version 5.3.3 (Release date: Sun Feb 7 15:39:52 2021 -0800) For further information on how to interpret these results please access https://meme-suite.org/meme. To get a copy of the MEME Suite software please access https://meme-suite.org. ******************************************************************************** ******************************************************************************** REFERENCE ******************************************************************************** If you use this program in your research, please cite: Timothy L. Bailey and Charles Elkan, "Fitting a mixture model by expectation maximization to discover motifs in biopolymers", Proceedings of the Second International Conference on Intelligent Systems for Molecular Biology, pp. 28-36, AAAI Press, Menlo Park, California, 1994. ******************************************************************************** ******************************************************************************** TRAINING SET ******************************************************************************** PRIMARY SEQUENCES= ../result/final_prediction/K562/fasta/RankLinear0.6_40/PHF21A.fasta CONTROL SEQUENCES= --none-- ALPHABET= ACGT Sequence name Weight Length Sequence name Weight Length ------------- ------ ------ ------------- ------ ------ chr12:95609919-95609999 1.0000 80 chr14:93651878-93651958 1.0000 80 chr1:207738994-207739074 1.0000 80 chr11:75274438-75274518 1.0000 80 chr17:44842544-44842624 1.0000 80 chr1:6300647-6300727 1.0000 80 chr8:8920939-8921019 1.0000 80 chr9:34701883-34701963 1.0000 80 chr9:46210544-46210624 1.0000 80 chr1:156635013-156635093 1.0000 80 chr15:52093808-52093888 1.0000 80 chr4:6732965-6733045 1.0000 80 chr2:145282391-145282471 1.0000 80 chr13:25588858-25588938 1.0000 80 chr4:4576691-4576771 1.0000 80 chr10:65226289-65226369 1.0000 80 chr7:86849972-86850052 1.0000 80 chr3:49838767-49838847 1.0000 80 chr1:201083332-201083412 1.0000 80 chr19:35581243-35581323 1.0000 80 chr3:193886278-193886358 1.0000 80 chr11:93275650-93275730 1.0000 80 chr1:93914778-93914858 1.0000 80 chr12:95848884-95848964 1.0000 80 chr14:75389950-75390030 1.0000 80 chr12:48591437-48591517 1.0000 80 chr3:167812527-167812607 1.0000 80 chr9:141044419-141044499 1.0000 80 chr8:61566213-61566293 1.0000 80 chr22:19869471-19869551 1.0000 80 chr9:115249995-115250075 1.0000 80 chrX:2610417-2610497 1.0000 80 chr1:53410373-53410453 1.0000 80 chr14:55031659-55031739 1.0000 80 chr21:46974749-46974829 1.0000 80 chr10:5624966-5625046 1.0000 80 chr1:39598791-39598871 1.0000 80 chr1:207872343-207872423 1.0000 80 chr1:9844804-9844884 1.0000 80 chr7:100199877-100199957 1.0000 80 chr12:7104230-7104310 1.0000 80 chr22:29138395-29138475 1.0000 80 chr22:26143545-26143625 1.0000 80 chr1:22710567-22710647 1.0000 80 chr10:60026695-60026775 1.0000 80 chr17:27388172-27388252 1.0000 80 chr12:117627564-11762764 1.0000 80 chr2:148602391-148602471 1.0000 80 chr7:99766126-99766206 1.0000 80 chr2:242295475-242295555 1.0000 80 chr8:95007023-95007103 1.0000 80 chr10:72647900-72647980 1.0000 80 chr20:31170716-31170796 1.0000 80 chr1:113216380-113216460 1.0000 80 chr1:16824086-16824166 1.0000 80 chr3:112281208-112281288 1.0000 80 chr6:30181204-30181284 1.0000 80 chr22:19559057-19559137 1.0000 80 chr19:34262523-34262603 1.0000 80 chr17:1532126-1532206 1.0000 80 chrX:53285637-53285717 1.0000 80 chr19:49933649-49933729 1.0000 80 chr3:155581218-155581298 1.0000 80 chr16:56761023-56761103 1.0000 80 chr4:147262132-147262212 1.0000 80 chr11:16311244-16311324 1.0000 80 chr6:150186165-150186245 1.0000 80 chr22:32865836-32865916 1.0000 80 chr9:139872713-139872793 1.0000 80 chr17:27276229-27276309 1.0000 80 chr6:44365640-44365720 1.0000 80 chr9:133356119-133356199 1.0000 80 chr1:206807817-206807897 1.0000 80 chr6:27689262-27689342 1.0000 80 chr1:207155749-207155829 1.0000 80 chr11:46143409-46143489 1.0000 80 chr16:50188937-50189017 1.0000 80 chr15:96870660-96870740 1.0000 80 chr10:111969049-11196912 1.0000 80 chr1:151430791-151430871 1.0000 80 chr1:29220460-29220540 1.0000 80 chr16:69830615-69830695 1.0000 80 chr2:103235206-103235286 1.0000 80 chr18:73555-73635 1.0000 80 chr1:27190800-27190880 1.0000 80 chr22:22652920-22653000 1.0000 80 chr9:71293505-71293585 1.0000 80 chr7:72350487-72350567 1.0000 80 chr5:176973577-176973657 1.0000 80 chr18:11981113-11981193 1.0000 80 chr22:42476343-42476423 1.0000 80 chr3:126074931-126075011 1.0000 80 chr11:118936158-11893623 1.0000 80 chr1:148556806-148556886 1.0000 80 chr8:143808009-143808089 1.0000 80 chr6:37184709-37184789 1.0000 80 chr1:39572848-39572928 1.0000 80 chr2:220341178-220341258 1.0000 80 chr1:200708272-200708352 1.0000 80 chr10:45454729-45454809 1.0000 80 chr11:96037328-96037408 1.0000 80 chr3:111393437-111393517 1.0000 80 chr18:68004556-68004636 1.0000 80 chr6:27562309-27562389 1.0000 80 chr20:57607767-57607847 1.0000 80 chr8:144852561-144852641 1.0000 80 chr16:71518008-71518088 1.0000 80 chr19:3013024-3013104 1.0000 80 chr19:2977987-2978067 1.0000 80 chr16:87900900-87900980 1.0000 80 chr15:41196373-41196453 1.0000 80 chr20:31169139-31169219 1.0000 80 chr14:24802870-24802950 1.0000 80 chr22:32332393-32332473 1.0000 80 chr17:77776903-77776983 1.0000 80 chr20:30517566-30517646 1.0000 80 chr5:159546917-159546997 1.0000 80 chr9:38062702-38062782 1.0000 80 chr2:113238778-113238858 1.0000 80 chr1:208418786-208418866 1.0000 80 chr19:18303065-18303145 1.0000 80 chr17:46092135-46092215 1.0000 80 chr1:93546102-93546182 1.0000 80 chr18:45938935-45939015 1.0000 80 chr19:6806569-6806649 1.0000 80 chr3:150489546-150489626 1.0000 80 chr21:36356292-36356372 1.0000 80 chr22:18403149-18403229 1.0000 80 chr17:42084542-42084622 1.0000 80 chr22:22973916-22973996 1.0000 80 chr2:39697153-39697233 1.0000 80 chr19:55166475-55166555 1.0000 80 chr12:10902924-10903004 1.0000 80 chr1:39007019-39007099 1.0000 80 chr4:8601548-8601628 1.0000 80 chr11:74203979-74204059 1.0000 80 chr6:86353829-86353909 1.0000 80 chr20:45152724-45152804 1.0000 80 chr22:42665534-42665614 1.0000 80 chr16:15982846-15982926 1.0000 80 chr1:114224722-114224802 1.0000 80 chr5:79704164-79704244 1.0000 80 chr7:2392889-2392969 1.0000 80 chr7:5465263-5465343 1.0000 80 chr14:53257588-53257668 1.0000 80 chr1:20848892-20848972 1.0000 80 chr2:47629567-47629647 1.0000 80 chr16:438117-438197 1.0000 80 chr15:85144444-85144524 1.0000 80 chr19:47117585-47117665 1.0000 80 chr10:82213303-82213383 1.0000 80 chr21:34753141-34753221 1.0000 80 chr1:15116008-15116088 1.0000 80 chr19:47551298-47551378 1.0000 80 chr9:139965077-139965157 1.0000 80 chr1:53166806-53166886 1.0000 80 chr11:11032196-11032276 1.0000 80 chr2:235422111-235422191 1.0000 80 chr15:65394063-65394143 1.0000 80 chr7:1572490-1572570 1.0000 80 chr3:154798185-154798265 1.0000 80 chr12:113795865-11379594 1.0000 80 chr22:20827560-20827640 1.0000 80 chr1:23886543-23886623 1.0000 80 chr6:157615396-157615476 1.0000 80 chr19:1864942-1865022 1.0000 80 chr7:32997641-32997721 1.0000 80 chr15:31781055-31781135 1.0000 80 chr1:40004962-40005042 1.0000 80 chr1:44471570-44471650 1.0000 80 chr14:77428250-77428330 1.0000 80 chr6:119862587-119862667 1.0000 80 chr7:76012516-76012596 1.0000 80 chr19:17033005-17033085 1.0000 80 chr1:110431762-110431842 1.0000 80 chr1:203258910-203258990 1.0000 80 chr20:30410798-30410878 1.0000 80 chr10:52153180-52153260 1.0000 80 chr19:15740197-15740277 1.0000 80 chr6:31937575-31937655 1.0000 80 chr1:70033362-70033442 1.0000 80 chr6:26034192-26034272 1.0000 80 chr4:123654589-123654669 1.0000 80 chr10:126277550-12627763 1.0000 80 chr6:135505008-135505088 1.0000 80 chr7:100202167-100202247 1.0000 80 chr12:48214270-48214350 1.0000 80 chr11:68625290-68625370 1.0000 80 chr2:9893557-9893637 1.0000 80 chr3:17785253-17785333 1.0000 80 chr7:86849093-86849173 1.0000 80 chr12:68752705-68752785 1.0000 80 chr7:30510023-30510103 1.0000 80 chr15:101818526-10181860 1.0000 80 chr19:54372299-54372379 1.0000 80 chr15:22834064-22834144 1.0000 80 chr9:127632054-127632134 1.0000 80 chr6:130539371-130539451 1.0000 80 chr11:12846191-12846271 1.0000 80 chr7:107103765-107103845 1.0000 80 chr19:44100189-44100269 1.0000 80 chr6:7389643-7389723 1.0000 80 chr16:70471370-70471450 1.0000 80 chr2:43454508-43454588 1.0000 80 chr3:4866625-4866705 1.0000 80 chr15:85198431-85198511 1.0000 80 chr1:1828757-1828837 1.0000 80 chr8:80680976-80681056 1.0000 80 chr19:955147-955227 1.0000 80 chr2:66660651-66660731 1.0000 80 chr2:3642628-3642708 1.0000 80 chr11:77013986-77014066 1.0000 80 chr7:100202878-100202958 1.0000 80 chr3:195934849-195934929 1.0000 80 chr1:226296960-226297040 1.0000 80 chr19:40931395-40931475 1.0000 80 chr19:3142425-3142505 1.0000 80 chr12:95466562-95466642 1.0000 80 chr5:95997647-95997727 1.0000 80 chr4:153494101-153494181 1.0000 80 chr6:2926285-2926365 1.0000 80 chr11:6378629-6378709 1.0000 80 chr19:48103652-48103732 1.0000 80 chr5:124060909-124060989 1.0000 80 chr7:2903468-2903548 1.0000 80 chr10:80685764-80685844 1.0000 80 chr19:36195210-36195290 1.0000 80 chr21:35014797-35014877 1.0000 80 chr19:52692733-52692813 1.0000 80 chr19:3580163-3580243 1.0000 80 chr11:47536964-47537044 1.0000 80 chr10:79165623-79165703 1.0000 80 chrX:24072418-24072498 1.0000 80 chr6:89791412-89791492 1.0000 80 chr20:32793449-32793529 1.0000 80 chr19:49141522-49141602 1.0000 80 chr19:36310996-36311076 1.0000 80 chr1:205218368-205218448 1.0000 80 chr12:107485879-10748595 1.0000 80 chr16:85854710-85854790 1.0000 80 chr3:124714313-124714393 1.0000 80 chr19:45982483-45982563 1.0000 80 chr7:138759915-138759995 1.0000 80 chr12:117111771-11711185 1.0000 80 chr6:158589697-158589777 1.0000 80 chr19:50767940-50768020 1.0000 80 chr13:76056710-76056790 1.0000 80 chr7:116593006-116593086 1.0000 80 chr1:52114061-52114141 1.0000 80 chr2:174220029-174220109 1.0000 80 ******************************************************************************** ******************************************************************************** COMMAND LINE SUMMARY ******************************************************************************** This information can also be useful in the event you wish to report a problem with the MEME software. command: meme -oc ../result/final_prediction/K562/inference_raw/MEME/RankLinear0.6_40_PHF21A/ -dna -nmotifs 5 -w 8 -maxsize 250000 -nostatus ../result/final_prediction/K562/fasta/RankLinear0.6_40/PHF21A.fasta model: mod= zoops nmotifs= 5 evt= inf objective function: em= E-value of product of p-values starts= E-value of product of p-values strands: + width: minw= 8 maxw= 8 nsites: minsites= 2 maxsites= 250 wnsites= 0.8 theta: spmap= uni spfuzz= 0.5 em: prior= dirichlet b= 0.01 maxiter= 50 distance= 1e-05 trim: wg= 11 ws= 1 endgaps= yes data: n= 20000 N= 250 sample: seed= 0 hsfrac= 0 searchsize= 20000 norand= no csites= 1000 Letter frequencies in dataset: A 0.238 C 0.261 G 0.26 T 0.241 Background letter frequencies (from file dataset with add-one prior applied): A 0.238 C 0.261 G 0.26 T 0.241 Background model order: 0 ******************************************************************************** ******************************************************************************** MOTIF HSWGATTT MEME-1 width = 8 sites = 115 llr = 849 E-value = 7.1e-060 ******************************************************************************** -------------------------------------------------------------------------------- Motif HSWGATTT MEME-1 Description -------------------------------------------------------------------------------- Simplified A 3:4:a::: pos.-specific C 462::::1 probability G 14:a:::1 matrix T 2:4::aa8 bits 2.1 *** 1.9 **** 1.7 **** 1.5 **** Relative 1.2 **** Entropy 1.0 ***** (10.7 bits) 0.8 * ***** 0.6 ******* 0.4 ******* 0.2 ******** 0.0 -------- Multilevel CCTGATTT consensus AGA sequence T -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif HSWGATTT MEME-1 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr2:220341178-220341258 55 1.42e-05 gatggccagt cctgattt ttcaagagag chr1:205218368-205218448 43 2.83e-05 CACTCCCACA CCAGATTT ATCCAACAAG chr19:3580163-3580243 62 2.83e-05 tgattgtcct ccagattt atccacgctg chr12:95466562-95466642 41 2.83e-05 ACGACCCTGG CCAGATTT GCCGTGAGAG chr3:4866625-4866705 34 2.83e-05 CCTTTGGTGG CCAGATTT GAGAGGTGTC chr3:17785253-17785333 62 2.83e-05 TTTAATCCGG CCAGattt atttatttat chr1:44471570-44471650 45 2.83e-05 GCTCCACCAG CCAGATTT CTTTGAAGGC chr16:438117-438197 30 2.83e-05 tgcacatagg ccagattt atgtttcact chr6:86353829-86353909 61 2.83e-05 GACACGAAGG CCAGATTT GGAAGCGAAA chr16:71518008-71518088 58 2.83e-05 AGTGAAATAA CCAGAttt gattaataca chr1:16824086-16824166 15 2.83e-05 cgcttgtcgg ccagattt ttgctcaaaa chr12:117627564-11762764 51 2.83e-05 gtgtgcaggg ccagattt catcctgggg chr1:39598791-39598871 38 2.83e-05 ATCTGGCTGT CCAGATTT CCTGTCCTCT chr14:55031659-55031739 47 2.83e-05 CGGAGATAGC CCAGATTT AGTCATCCAG chr12:95848884-95848964 67 2.83e-05 actgaggttg ccagattt aataat chr15:22834064-22834144 71 4.12e-05 GTGTCATGAC ACTGATTT AA chr12:68752705-68752785 27 4.12e-05 AGTCTAGGAG ACTGATTT ACTAGGGTTT chr3:154798185-154798265 38 4.12e-05 CTGTACAGAC ACTGATTT TTTTTTCTTC chr1:114224722-114224802 56 4.12e-05 TGCTAACTGC ACTGATTT TTTTTTTTTT chr2:39697153-39697233 22 4.12e-05 AGGAACTGAA ACTGATTT GCCCAAGGTC chr18:11981113-11981193 51 4.12e-05 CAGGCTCGGC ACTGATTT GTGTTCAGGG chr3:49838767-49838847 63 4.12e-05 ctctgactac actgattt cctcccaccc chr6:158589697-158589777 29 6.82e-05 CCGCACGGGA CGTGATTT ATTTAGTGAA chr1:23886543-23886623 23 6.82e-05 AATGAAGAAA ACAGATTT GCGCTAGGCG chr1:53166806-53166886 31 6.82e-05 agtgcagtgg cgtgattt tggctcaccg chr8:143808009-143808089 16 6.82e-05 TCCGCCCGGC CGTGATTT GCTCCGGTTT chr18:73555-73635 57 6.82e-05 TTTTCCAGGC CGTGATTT TGGAAATTTC chr2:242295475-242295555 27 6.82e-05 CGAGCGCTGC ACAGATTT ATATCCTACG chr10:65226289-65226369 24 6.82e-05 TAAGCTATTC ACAGATTT AAATTCGTCA chr1:6300647-6300727 69 6.82e-05 GAGGGGGACA ACAGATTT CTCC chr2:66660651-66660731 39 9.53e-05 GGCTGCCTAC CGAGATTT GGGTGAGCTC chr12:48214270-48214350 14 9.53e-05 AGTTCCAGGA TCTGATTT GAATCACTGC chr15:96870660-96870740 44 9.53e-05 CAGCATATGC TCTGATTT AGCACTGTAA chr6:30181204-30181284 21 9.53e-05 GGCCCTTCGC CGAGATTT CTCCCGGACC chr19:15740197-15740277 31 1.08e-04 AACTACCTTT TCAGATTT CCGGTAATAA chr3:150489546-150489626 29 1.08e-04 CTGCCAGATC TCAGATTT AAGCCAAATC chr6:150186165-150186245 16 1.08e-04 TCACATGCAC TCAGATTT CCACAAATAT chr3:124714313-124714393 49 1.21e-04 CTTGAACTGC AGTGATTT AGAAAACACA chr6:135505008-135505088 60 1.21e-04 agagagagga agtgattt gtccaagtca chr2:47629567-47629647 70 1.21e-04 gaataaaggc agtgattt ttc chr15:41196373-41196453 66 1.21e-04 AGCTGGGAGC AGTGATTT CTGTCAC chr1:200708272-200708352 53 1.21e-04 TGTGAGCCGC AGTGATTT TGACGTTTTC chr2:148602391-148602471 18 1.21e-04 CGGAGCTGAC AGTGATTT TGACAGTGAT chr9:115249995-115250075 29 1.21e-04 GGCTGCGCAC AGTGATTT GTGTTTGTTA chr1:93914778-93914858 67 1.21e-04 TGCGGAGGGC AGTGATTT CTCAGG chr4:4576691-4576771 5 1.21e-04 TTGC AGTGATTT Tacacacaca chr15:52093808-52093888 18 1.21e-04 GTCAATGTGC AGTGATTT AATCAGGTGC chr7:100202878-100202958 26 1.34e-04 TGcagccagc agagattt attgaagatc chr15:85198431-85198511 58 1.34e-04 ATGGAGTAAC AGAGATTT GAGCTCAGGA chr1:39007019-39007099 68 1.34e-04 aattctcagc agagattt ttcac chr16:50188937-50189017 35 1.34e-04 TCTAGGGGGT AGAGATTT ATGCTAATGA chr11:75274438-75274518 42 1.34e-04 GACTCCCAGC AGAGATTT TTTTTTTGTA chr7:107103765-107103845 60 1.47e-04 TAACCAAAGT TGTGATTT TCTTTTCTTC chr8:144852561-144852641 48 1.47e-04 TCTCCTTCGC TGTGATTT TCCCACATGG chr1:148556806-148556886 49 1.47e-04 AAAGAGTTGC TGTGATTT CCCTGTATCT chr22:42476343-42476423 49 1.47e-04 ATttaattca tgtgattt acagtcctga chr9:71293505-71293585 56 1.47e-04 AACCTGCTGC TGTGATTT CTCCTTGGGT chr1:29220460-29220540 19 1.47e-04 GAGGGCACTC TGTGATTT TAGGATCCTA chrX:53285637-53285717 39 1.47e-04 CAGTGCTCGC TGTGATTT CCCTCCCAGT chr8:95007023-95007103 18 1.47e-04 cagtaaatac tgTGATTT ACCTTGTTTA chr1:207872343-207872423 38 1.47e-04 TTCTGGAGGC TGTGATTT TTCCAGAATA chr1:207738994-207739074 36 1.47e-04 TTCTGGAGGC TGTGATTT TTCCAGAATA chr2:174220029-174220109 3 1.75e-04 GT CCCGATTT TGCCTGCCAG chr6:89791412-89791492 5 1.75e-04 CAGC CCCGATTT AGAAGGCTGG chr1:110431762-110431842 49 1.75e-04 caagggaggg cccgattt cacattagag chr21:34753141-34753221 14 1.75e-04 GCTGGGTTGG CCCGATTT CTTCCTGCCT chr15:85144444-85144524 68 1.75e-04 GCCCTGCAGC CCCGATTT ACGCG chr4:8601548-8601628 51 1.75e-04 cccgccaggc cccgattt cctccttgtg chr20:57607767-57607847 57 1.75e-04 TCCTGAGAGC TGAGATTT AGAAAGGCTC chr6:27689262-27689342 55 1.75e-04 AAGGCACTGT CCCGATTT TTTCTTCAGA chr9:133356119-133356199 66 1.75e-04 ACCGTGCAGG CCCGATTT CGTGGTC chr17:27276229-27276309 62 1.75e-04 TCTAACCCGG CCCGATTT CCTAAGAGGC chr16:56761023-56761103 34 1.75e-04 ACACAGGGAC TGAGATTT GGGGCAGGAA chr22:26143545-26143625 33 1.75e-04 CTGGAGGAGC TGAGATTT TTTTTTTCTA chrX:2610417-2610497 39 1.75e-04 ACGGAGGAGG CCCGATTT GTGTTGATAG chr9:46210544-46210624 43 1.89e-04 tccaagctgc accgattt gtaagccccc chr20:32793449-32793529 19 2.62e-04 tttacagagc gctgattt ctccatttta chr9:141044419-141044499 61 2.62e-04 AAATCAAGGC GCTGATTT CCAGAGATTC chr11:12846191-12846271 54 3.07e-04 AGGGTTGGGG CCAGATTG CTAGAGCCCC chr20:30410798-30410878 50 3.07e-04 GGTGGTCTGG CCAGATTG CGGTGTTATT chr20:30517566-30517646 43 3.07e-04 GCCCATCTGG CCAGATTG CTTCCCAGAA chr22:32865836-32865916 33 3.07e-04 TCTGTGTAGC GCAGATTT ATGTGTTTGT chr17:44842544-44842624 55 3.07e-04 acaggctcag ccagattg aagggacaca chr19:50767940-50768020 49 3.36e-04 agagctccag ccagattc ccaggtttca chr19:49141522-49141602 70 3.36e-04 ATCGGGACGT CCAGATTC AGC chr17:46092135-46092215 13 3.36e-04 ATCTTCCTCC CCAGATTC AACTGTTTTC chr21:46974749-46974829 15 3.36e-04 TTTTAACTGT CCAGATTC ATTGAGTCCC chr13:25588858-25588938 54 3.36e-04 acaacgctgc ccagattc taagtgtgag chr11:11032196-11032276 43 3.50e-04 TCTGCTACTC ACTGATTG ATGTTGTCCA chr1:156635013-156635093 22 3.50e-04 TTGTCCTTGC ACTGATTG GAGGGGTGGG chr19:44100189-44100269 55 4.08e-04 GCCAGGGAGC GGTGATTT AGAGATGCCG chr6:130539371-130539451 24 4.08e-04 ttctcgcctc acagattg aattccaagt chr1:40004962-40005042 19 4.08e-04 AGCTTAACTC GGTGATTT CACTGAAAGT chr11:96037328-96037408 31 4.08e-04 AGGAGGGGAC ACTGATTC TACTGCTGAG chr3:155581218-155581298 23 4.80e-04 ggaaaaaggt ggagattt ctcagaaatg chr1:15116008-15116088 48 5.37e-04 CAGGTTCATC TCTGATTC TACATTCTCC chr16:15982846-15982926 39 5.37e-04 ccatagagtt tctgattc tgtaaatctg chr22:29138395-29138475 72 5.37e-04 AGAGAAGTGT CTTGATTT C chr10:45454729-45454809 56 5.77e-04 AAGTGCCTGC AGTGATTG CAGCGCCTGC chr19:45982483-45982563 41 7.17e-04 gacatcctgt cccgattg agtttaaaca chr19:40931395-40931475 34 7.17e-04 GATTCCCGGC TGTGATTC CTGCCGGCCT chr7:2392889-2392969 63 7.17e-04 gctggaaggt cccgattg cagcggcgct chr22:42665534-42665614 18 7.17e-04 GAGGGATCGG CCCGATTG GCCACGCTCC chr6:27562309-27562389 49 7.17e-04 caggcatggc tgagattg cgcatggctg chr7:72350487-72350567 61 7.17e-04 GAGGGAGCGT CCCGATTG CTTGCCGGAG chr3:167812527-167812607 44 7.17e-04 GTTTCCCTGC CCCGATTG CAGCTGGGCC chrX:24072418-24072498 55 7.60e-04 AGCTGGGGAC TTTGATTT TGCTAGCCCT chr10:79165623-79165703 57 7.60e-04 GGAAGCTGGT CCCGATTC CTGCTTCTCT chr19:48103652-48103732 8 7.60e-04 CAGTAGG CCCGATTC AAATCTGGCC chr19:1864942-1865022 39 7.60e-04 GAGGCCCTGA CCCGATTC GGGGCTTCTC chr9:139965077-139965157 39 7.60e-04 TGAGAGGAGG TTTGATTT TTTTTTTTTT chr1:113216380-113216460 57 7.60e-04 CAACACTAGC TTTGATTT ATTTGAAAGT chr1:9844804-9844884 24 7.60e-04 GTTCTCAGGC TTTGATTT TAAAATCCTG chr17:1532126-1532206 61 9.26e-04 ACTGCCGCCC GCTGATTG GCTGAGCGGG chr14:24802870-24802950 60 1.13e-03 AATTTGCTCG GGAGATTC CCGGAGCCGG -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif HSWGATTT MEME-1 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr2:220341178-220341258 1.4e-05 54_[+1]_18 chr1:205218368-205218448 2.8e-05 42_[+1]_30 chr19:3580163-3580243 2.8e-05 61_[+1]_11 chr12:95466562-95466642 2.8e-05 40_[+1]_32 chr3:4866625-4866705 2.8e-05 33_[+1]_39 chr3:17785253-17785333 2.8e-05 61_[+1]_11 chr1:44471570-44471650 2.8e-05 44_[+1]_28 chr16:438117-438197 2.8e-05 29_[+1]_43 chr6:86353829-86353909 2.8e-05 60_[+1]_12 chr16:71518008-71518088 2.8e-05 57_[+1]_15 chr1:16824086-16824166 2.8e-05 14_[+1]_58 chr12:117627564-11762764 2.8e-05 50_[+1]_22 chr1:39598791-39598871 2.8e-05 37_[+1]_35 chr14:55031659-55031739 2.8e-05 46_[+1]_26 chr12:95848884-95848964 2.8e-05 66_[+1]_6 chr15:22834064-22834144 4.1e-05 70_[+1]_2 chr12:68752705-68752785 4.1e-05 26_[+1]_46 chr3:154798185-154798265 4.1e-05 37_[+1]_35 chr1:114224722-114224802 4.1e-05 55_[+1]_17 chr2:39697153-39697233 4.1e-05 21_[+1]_51 chr18:11981113-11981193 4.1e-05 50_[+1]_22 chr3:49838767-49838847 4.1e-05 62_[+1]_10 chr6:158589697-158589777 6.8e-05 28_[+1]_44 chr1:23886543-23886623 6.8e-05 22_[+1]_50 chr1:53166806-53166886 6.8e-05 30_[+1]_42 chr8:143808009-143808089 6.8e-05 15_[+1]_57 chr18:73555-73635 6.8e-05 56_[+1]_16 chr2:242295475-242295555 6.8e-05 26_[+1]_46 chr10:65226289-65226369 6.8e-05 23_[+1]_49 chr1:6300647-6300727 6.8e-05 68_[+1]_4 chr2:66660651-66660731 9.5e-05 38_[+1]_34 chr12:48214270-48214350 9.5e-05 13_[+1]_59 chr15:96870660-96870740 9.5e-05 43_[+1]_29 chr6:30181204-30181284 9.5e-05 20_[+1]_52 chr19:15740197-15740277 0.00011 30_[+1]_42 chr3:150489546-150489626 0.00011 28_[+1]_44 chr6:150186165-150186245 0.00011 15_[+1]_57 chr3:124714313-124714393 0.00012 48_[+1]_24 chr6:135505008-135505088 0.00012 59_[+1]_13 chr2:47629567-47629647 0.00012 69_[+1]_3 chr15:41196373-41196453 0.00012 65_[+1]_7 chr1:200708272-200708352 0.00012 52_[+1]_20 chr2:148602391-148602471 0.00012 17_[+1]_55 chr9:115249995-115250075 0.00012 28_[+1]_44 chr1:93914778-93914858 0.00012 66_[+1]_6 chr4:4576691-4576771 0.00012 4_[+1]_68 chr15:52093808-52093888 0.00012 17_[+1]_55 chr7:100202878-100202958 0.00013 25_[+1]_47 chr15:85198431-85198511 0.00013 57_[+1]_15 chr1:39007019-39007099 0.00013 67_[+1]_5 chr16:50188937-50189017 0.00013 34_[+1]_38 chr11:75274438-75274518 0.00013 41_[+1]_31 chr7:107103765-107103845 0.00015 59_[+1]_13 chr8:144852561-144852641 0.00015 47_[+1]_25 chr1:148556806-148556886 0.00015 48_[+1]_24 chr22:42476343-42476423 0.00015 48_[+1]_24 chr9:71293505-71293585 0.00015 55_[+1]_17 chr1:29220460-29220540 0.00015 18_[+1]_54 chrX:53285637-53285717 0.00015 38_[+1]_34 chr8:95007023-95007103 0.00015 17_[+1]_55 chr1:207872343-207872423 0.00015 37_[+1]_35 chr1:207738994-207739074 0.00015 35_[+1]_37 chr2:174220029-174220109 0.00018 2_[+1]_70 chr6:89791412-89791492 0.00018 4_[+1]_68 chr1:110431762-110431842 0.00018 48_[+1]_24 chr21:34753141-34753221 0.00018 13_[+1]_59 chr15:85144444-85144524 0.00018 67_[+1]_5 chr4:8601548-8601628 0.00018 50_[+1]_22 chr20:57607767-57607847 0.00018 56_[+1]_16 chr6:27689262-27689342 0.00018 54_[+1]_18 chr9:133356119-133356199 0.00018 65_[+1]_7 chr17:27276229-27276309 0.00018 61_[+1]_11 chr16:56761023-56761103 0.00018 33_[+1]_39 chr22:26143545-26143625 0.00018 32_[+1]_40 chrX:2610417-2610497 0.00018 38_[+1]_34 chr9:46210544-46210624 0.00019 42_[+1]_30 chr20:32793449-32793529 0.00026 18_[+1]_54 chr9:141044419-141044499 0.00026 60_[+1]_12 chr11:12846191-12846271 0.00031 53_[+1]_19 chr20:30410798-30410878 0.00031 49_[+1]_23 chr20:30517566-30517646 0.00031 42_[+1]_30 chr22:32865836-32865916 0.00031 32_[+1]_40 chr17:44842544-44842624 0.00031 54_[+1]_18 chr19:50767940-50768020 0.00034 48_[+1]_24 chr19:49141522-49141602 0.00034 69_[+1]_3 chr17:46092135-46092215 0.00034 12_[+1]_60 chr21:46974749-46974829 0.00034 14_[+1]_58 chr13:25588858-25588938 0.00034 53_[+1]_19 chr11:11032196-11032276 0.00035 42_[+1]_30 chr1:156635013-156635093 0.00035 21_[+1]_51 chr19:44100189-44100269 0.00041 54_[+1]_18 chr6:130539371-130539451 0.00041 23_[+1]_49 chr1:40004962-40005042 0.00041 18_[+1]_54 chr11:96037328-96037408 0.00041 30_[+1]_42 chr3:155581218-155581298 0.00048 22_[+1]_50 chr1:15116008-15116088 0.00054 47_[+1]_25 chr16:15982846-15982926 0.00054 38_[+1]_34 chr22:29138395-29138475 0.00054 71_[+1]_1 chr10:45454729-45454809 0.00058 55_[+1]_17 chr19:45982483-45982563 0.00072 40_[+1]_32 chr19:40931395-40931475 0.00072 33_[+1]_39 chr7:2392889-2392969 0.00072 62_[+1]_10 chr22:42665534-42665614 0.00072 17_[+1]_55 chr6:27562309-27562389 0.00072 48_[+1]_24 chr7:72350487-72350567 0.00072 60_[+1]_12 chr3:167812527-167812607 0.00072 43_[+1]_29 chrX:24072418-24072498 0.00076 54_[+1]_18 chr10:79165623-79165703 0.00076 56_[+1]_16 chr19:48103652-48103732 0.00076 7_[+1]_65 chr19:1864942-1865022 0.00076 38_[+1]_34 chr9:139965077-139965157 0.00076 38_[+1]_34 chr1:113216380-113216460 0.00076 56_[+1]_16 chr1:9844804-9844884 0.00076 23_[+1]_49 chr17:1532126-1532206 0.00093 60_[+1]_12 chr14:24802870-24802950 0.0011 59_[+1]_13 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif HSWGATTT MEME-1 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF HSWGATTT width=8 seqs=115 chr2:220341178-220341258 ( 55) CCTGATTT 1 chr1:205218368-205218448 ( 43) CCAGATTT 1 chr19:3580163-3580243 ( 62) CCAGATTT 1 chr12:95466562-95466642 ( 41) CCAGATTT 1 chr3:4866625-4866705 ( 34) CCAGATTT 1 chr3:17785253-17785333 ( 62) CCAGATTT 1 chr1:44471570-44471650 ( 45) CCAGATTT 1 chr16:438117-438197 ( 30) CCAGATTT 1 chr6:86353829-86353909 ( 61) CCAGATTT 1 chr16:71518008-71518088 ( 58) CCAGATTT 1 chr1:16824086-16824166 ( 15) CCAGATTT 1 chr12:117627564-11762764 ( 51) CCAGATTT 1 chr1:39598791-39598871 ( 38) CCAGATTT 1 chr14:55031659-55031739 ( 47) CCAGATTT 1 chr12:95848884-95848964 ( 67) CCAGATTT 1 chr15:22834064-22834144 ( 71) ACTGATTT 1 chr12:68752705-68752785 ( 27) ACTGATTT 1 chr3:154798185-154798265 ( 38) ACTGATTT 1 chr1:114224722-114224802 ( 56) ACTGATTT 1 chr2:39697153-39697233 ( 22) ACTGATTT 1 chr18:11981113-11981193 ( 51) ACTGATTT 1 chr3:49838767-49838847 ( 63) ACTGATTT 1 chr6:158589697-158589777 ( 29) CGTGATTT 1 chr1:23886543-23886623 ( 23) ACAGATTT 1 chr1:53166806-53166886 ( 31) CGTGATTT 1 chr8:143808009-143808089 ( 16) CGTGATTT 1 chr18:73555-73635 ( 57) CGTGATTT 1 chr2:242295475-242295555 ( 27) ACAGATTT 1 chr10:65226289-65226369 ( 24) ACAGATTT 1 chr1:6300647-6300727 ( 69) ACAGATTT 1 chr2:66660651-66660731 ( 39) CGAGATTT 1 chr12:48214270-48214350 ( 14) TCTGATTT 1 chr15:96870660-96870740 ( 44) TCTGATTT 1 chr6:30181204-30181284 ( 21) CGAGATTT 1 chr19:15740197-15740277 ( 31) TCAGATTT 1 chr3:150489546-150489626 ( 29) TCAGATTT 1 chr6:150186165-150186245 ( 16) TCAGATTT 1 chr3:124714313-124714393 ( 49) AGTGATTT 1 chr6:135505008-135505088 ( 60) AGTGATTT 1 chr2:47629567-47629647 ( 70) AGTGATTT 1 chr15:41196373-41196453 ( 66) AGTGATTT 1 chr1:200708272-200708352 ( 53) AGTGATTT 1 chr2:148602391-148602471 ( 18) AGTGATTT 1 chr9:115249995-115250075 ( 29) AGTGATTT 1 chr1:93914778-93914858 ( 67) AGTGATTT 1 chr4:4576691-4576771 ( 5) AGTGATTT 1 chr15:52093808-52093888 ( 18) AGTGATTT 1 chr7:100202878-100202958 ( 26) AGAGATTT 1 chr15:85198431-85198511 ( 58) AGAGATTT 1 chr1:39007019-39007099 ( 68) AGAGATTT 1 chr16:50188937-50189017 ( 35) AGAGATTT 1 chr11:75274438-75274518 ( 42) AGAGATTT 1 chr7:107103765-107103845 ( 60) TGTGATTT 1 chr8:144852561-144852641 ( 48) TGTGATTT 1 chr1:148556806-148556886 ( 49) TGTGATTT 1 chr22:42476343-42476423 ( 49) TGTGATTT 1 chr9:71293505-71293585 ( 56) TGTGATTT 1 chr1:29220460-29220540 ( 19) TGTGATTT 1 chrX:53285637-53285717 ( 39) TGTGATTT 1 chr8:95007023-95007103 ( 18) TGTGATTT 1 chr1:207872343-207872423 ( 38) TGTGATTT 1 chr1:207738994-207739074 ( 36) TGTGATTT 1 chr2:174220029-174220109 ( 3) CCCGATTT 1 chr6:89791412-89791492 ( 5) CCCGATTT 1 chr1:110431762-110431842 ( 49) CCCGATTT 1 chr21:34753141-34753221 ( 14) CCCGATTT 1 chr15:85144444-85144524 ( 68) CCCGATTT 1 chr4:8601548-8601628 ( 51) CCCGATTT 1 chr20:57607767-57607847 ( 57) TGAGATTT 1 chr6:27689262-27689342 ( 55) CCCGATTT 1 chr9:133356119-133356199 ( 66) CCCGATTT 1 chr17:27276229-27276309 ( 62) CCCGATTT 1 chr16:56761023-56761103 ( 34) TGAGATTT 1 chr22:26143545-26143625 ( 33) TGAGATTT 1 chrX:2610417-2610497 ( 39) CCCGATTT 1 chr9:46210544-46210624 ( 43) ACCGATTT 1 chr20:32793449-32793529 ( 19) GCTGATTT 1 chr9:141044419-141044499 ( 61) GCTGATTT 1 chr11:12846191-12846271 ( 54) CCAGATTG 1 chr20:30410798-30410878 ( 50) CCAGATTG 1 chr20:30517566-30517646 ( 43) CCAGATTG 1 chr22:32865836-32865916 ( 33) GCAGATTT 1 chr17:44842544-44842624 ( 55) CCAGATTG 1 chr19:50767940-50768020 ( 49) CCAGATTC 1 chr19:49141522-49141602 ( 70) CCAGATTC 1 chr17:46092135-46092215 ( 13) CCAGATTC 1 chr21:46974749-46974829 ( 15) CCAGATTC 1 chr13:25588858-25588938 ( 54) CCAGATTC 1 chr11:11032196-11032276 ( 43) ACTGATTG 1 chr1:156635013-156635093 ( 22) ACTGATTG 1 chr19:44100189-44100269 ( 55) GGTGATTT 1 chr6:130539371-130539451 ( 24) ACAGATTG 1 chr1:40004962-40005042 ( 19) GGTGATTT 1 chr11:96037328-96037408 ( 31) ACTGATTC 1 chr3:155581218-155581298 ( 23) GGAGATTT 1 chr1:15116008-15116088 ( 48) TCTGATTC 1 chr16:15982846-15982926 ( 39) TCTGATTC 1 chr22:29138395-29138475 ( 72) CTTGATTT 1 chr10:45454729-45454809 ( 56) AGTGATTG 1 chr19:45982483-45982563 ( 41) CCCGATTG 1 chr19:40931395-40931475 ( 34) TGTGATTC 1 chr7:2392889-2392969 ( 63) CCCGATTG 1 chr22:42665534-42665614 ( 18) CCCGATTG 1 chr6:27562309-27562389 ( 49) TGAGATTG 1 chr7:72350487-72350567 ( 61) CCCGATTG 1 chr3:167812527-167812607 ( 44) CCCGATTG 1 chrX:24072418-24072498 ( 55) TTTGATTT 1 chr10:79165623-79165703 ( 57) CCCGATTC 1 chr19:48103652-48103732 ( 8) CCCGATTC 1 chr19:1864942-1865022 ( 39) CCCGATTC 1 chr9:139965077-139965157 ( 39) TTTGATTT 1 chr1:113216380-113216460 ( 57) TTTGATTT 1 chr1:9844804-9844884 ( 24) TTTGATTT 1 chr17:1532126-1532206 ( 61) GCTGATTG 1 chr14:24802870-24802950 ( 60) GGAGATTC 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif HSWGATTT MEME-1 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 8.54888 E= 7.1e-060 23 71 -190 -9 -1349 120 45 -247 72 -66 -1349 88 -1349 -1349 194 -1349 207 -1349 -1349 -1349 -1349 -1349 -1349 205 -1349 -1349 -1349 205 -1349 -121 -100 165 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif HSWGATTT MEME-1 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 115 E= 7.1e-060 0.278261 0.426087 0.069565 0.226087 0.000000 0.600000 0.356522 0.043478 0.391304 0.165217 0.000000 0.443478 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.113043 0.130435 0.756522 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif HSWGATTT MEME-1 regular expression -------------------------------------------------------------------------------- [CAT][CG][TA]GATTT -------------------------------------------------------------------------------- Time 5.05 secs. ******************************************************************************** ******************************************************************************** MOTIF AATCWSDG MEME-2 width = 8 sites = 75 llr = 599 E-value = 7.7e-036 ******************************************************************************** -------------------------------------------------------------------------------- Motif AATCWSDG MEME-2 Description -------------------------------------------------------------------------------- Simplified A aa::412: pos.-specific C :::a:5:2 probability G :::::448 matrix T ::a:6:3: bits 2.1 *** 1.9 **** 1.7 **** 1.5 **** Relative 1.2 **** * Entropy 1.0 ***** * (11.5 bits) 0.8 ***** * 0.6 ****** * 0.4 ******** 0.2 ******** 0.0 -------- Multilevel AATCTCGG consensus AGTC sequence A -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AATCWSDG MEME-2 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr1:20848892-20848972 31 1.52e-05 AGGGTCCTTC AATCTCGG CAGCCTAAAA chr11:118936158-11893623 58 1.52e-05 CTGGCAGGCC AATCTCGG CCTTTGTAAC chr16:15982846-15982926 51 3.02e-05 tgattctgta aatctggg gtgaggccct chr2:113238778-113238858 44 3.02e-05 GGCCCCGTGG AATCTGGG CAACGATGGG chr19:2977987-2978067 24 3.02e-05 cgcCCCCATG AATCTGGG CAGCTGGAGG chr4:6732965-6733045 8 3.02e-05 CCCAGTA AATCTGGG CTGCCCTAAT chr12:117111771-11711185 41 4.43e-05 cctgcacaca aatctctg cctcagaatc chr7:2903468-2903548 29 4.43e-05 tgccctttcc aatctctg cttcctgtcc chr11:11032196-11032276 29 4.43e-05 GAGGCTCCGG AATCTCTG CTACTCACTG chr12:10902924-10903004 34 4.43e-05 GGTTCCAGTA AATCTCTG CTGCTCTTGT chr5:159546917-159546997 8 4.43e-05 TCCCAAG AATCTCTG CGCAGAGATC chr18:73555-73635 21 4.43e-05 AGCTCTGGGG AATCTCTG AAAATCAGCG chr11:16311244-16311324 45 4.43e-05 CCAGGATTTA AATCTCTG TAAGGAATAA chr19:15740197-15740277 48 5.83e-05 TCCGGTAATA AATCTGTG TTGGCCCCTG chr19:47117585-47117665 39 5.83e-05 CCACGGCATA AATCTGTG TGCGCCGGTG chr20:57607767-57607847 25 5.83e-05 GGCTTTTTTA AATCTGTG GACAGACAAG chr22:32865836-32865916 21 5.83e-05 CTGCTAATTG AATCTGTG TAGCGCAGAT chr5:79704164-79704244 54 7.32e-05 CCGGGAGGGC AATCACGG CGGCTGTTTG chr3:111393437-111393517 34 7.32e-05 GCCAGCGGCC AATCACGG GCCGCCTAGC chr3:126074931-126075011 63 7.32e-05 TCAGCGTGCA AATCACGG GGGTGGCGGC chr1:151430791-151430871 53 7.32e-05 CCATTTTATA AATCACGG CGCCATCCCA chr1:22710567-22710647 8 7.32e-05 gaggcaa aatcacgg cgtatctgtt chr14:55031659-55031739 32 7.32e-05 TTTCCTCTGA AATCACGG AGATAGCCCA chr9:141044419-141044499 35 7.32e-05 AAATTTCCAA AATCACGG CCTGGAAAAA chr7:86849093-86849173 26 1.02e-04 CACTTCCTCA AATCTCAG CCCTTGGCGC chr6:119862587-119862667 60 1.02e-04 cagtggttta aatctcag tttatttctc chr10:82213303-82213383 57 1.02e-04 GTTAGGAAGA AATCTCAG CCACGATCCA chr20:45152724-45152804 43 1.02e-04 GGCCAGAAGA AATCTCAG TAGAACTCAG chr3:150489546-150489626 43 1.02e-04 ATTTAAGCCA AATCTCAG AAGAGAGAAT chr6:27562309-27562389 68 1.02e-04 gcatggctgt aatctcag ctact chr1:39572848-39572928 25 1.02e-04 TAGGTGAAGA AATCTCAG CACCTCACTG chr6:37184709-37184789 45 1.02e-04 tgagaaaata aatctcag ctctttataa chr5:176973577-176973657 8 1.02e-04 TGAGAAG AATCTCAG ACTATTCTAA chr4:153494101-153494181 38 1.30e-04 TCACCTTTTA AATCACTG CCTCTTCCAG chr12:48214270-48214350 23 1.30e-04 ATCTGATTTG AATCACTG CCCAGCCCTC chr10:52153180-52153260 11 1.30e-04 AAGAAGCACA AATCACTG CCTGTCACTT chr19:6806569-6806649 70 1.30e-04 gcggagagta aatcactg tcc chr1:208418786-208418866 28 1.30e-04 AAACAACAAA AATCACTG CGAATACCTA chr16:69830615-69830695 9 1.30e-04 CGTGTGTA AATCACTG CACCTCATTT chr4:147262132-147262212 46 1.30e-04 CATTAGTATG AATCACTG CATGTTTAAA chr19:34262523-34262603 52 1.30e-04 AGAGGCCGTA AATCTGAG CCCGCCTGCA chr10:5624966-5625046 29 1.30e-04 GCTCGTCACA AATCACTG CCCAACCAAT chr19:3142425-3142505 31 1.44e-04 AGGAAAAAAA AATCAGTG CATCACAAAA chr15:101818526-10181860 41 1.44e-04 GCGTGAACGC AATCAGTG TTTCTTCAAT chr7:32997641-32997721 69 1.44e-04 AGTGTAAAAT AATCAGTG TAAG chr15:65394063-65394143 45 1.44e-04 tggaaacaaa aatcagtg cgatccagtc chr15:85198431-85198511 38 1.57e-04 CCCAGCCAGA AATCACAG TAATGGAGTA chr6:157615396-157615476 31 1.57e-04 tacaggcatg aatcacag cacTGCCTGC chr2:235422111-235422191 72 1.57e-04 acgtggagat aatcacag t chr12:48591437-48591517 24 1.57e-04 TTACAAAATA AATCACAG ACGAGTGGAG chr1:203258910-203258990 61 1.71e-04 TGGACTCAGA AATCAGAG CGCCTCCCCC chr18:45938935-45939015 26 1.71e-04 GCTTTGAATA AATCAGAG CAGAAGAGAA chr16:87900900-87900980 58 1.71e-04 CAAAAAAAGA AATCAGAG TCATCCCCTA chr19:48103652-48103732 17 2.01e-04 GCCCGATTCA AATCTGGC CAATGATAGT chr11:77013986-77014066 2 2.01e-04 c aatctggc cgtcctgctg chr7:30510023-30510103 39 2.01e-04 CGAATGAATG AATCTGGC CGGGTGCACT chr15:31781055-31781135 52 2.01e-04 GCTTTTCATT AATCTGGC TTGGGATTGG chr12:113795865-11379594 20 2.01e-04 CCATTAAATA AATCTggc cgggcgcggt chr7:1572490-1572570 15 2.01e-04 GGGAAATGGA AATCTGGC CAGCTGAGAG chr22:22973916-22973996 38 2.01e-04 CCTAGGATGG AATCTGGC TGGGCCTCTG chr22:18403149-18403229 24 2.01e-04 CTCCCTCTCC AATCTGGC CTCTGTCTCC chr14:24802870-24802950 41 2.01e-04 AATGTCTCCA AATCTGGC CAATTTGCTC chr22:19559057-19559137 31 2.01e-04 CTGGTCAGTA AATCTGGC CAAGTGAGTC chr3:112281208-112281288 26 2.01e-04 TGTGAAGGGA AATCTGGC CCCCTCCTGT chr12:7104230-7104310 5 2.01e-04 tctc aatctggc ctctaccctt chr1:39598791-39598871 27 2.01e-04 CTGGGACAGG AATCTGGC TGTCCAGATT chr1:53410373-53410453 34 2.01e-04 AGTAATAAGA AATCTggc cgggcatggt chr11:93275650-93275730 48 2.01e-04 GTCTGAGGTG AATCTGGC CGCTGGGGAG chr1:201083332-201083412 17 2.01e-04 CGCCAGCAGC AATCTGGC CTCCCATCCC chr11:47536964-47537044 56 2.29e-04 CATGAGGCCA AATCTGTC TTATCTAGTG chr22:20827560-20827640 19 3.15e-04 tgacagactg aatctagg aggacctggg chr17:42084542-42084622 3 3.42e-04 CA AATCTATG CAGACCACTG chr10:126277550-12627763 16 3.83e-04 AGCGCCCATA AATCAAGG CTTTCCCCAG chr1:110431762-110431842 36 3.83e-04 gaagagatag aatcaagg gagggcccga chr19:52692733-52692813 61 4.20e-04 ATCAAGCACA AATCAAAG TCTCACTCCC -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AATCWSDG MEME-2 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr1:20848892-20848972 1.5e-05 30_[+2]_42 chr11:118936158-11893623 1.5e-05 57_[+2]_15 chr16:15982846-15982926 3e-05 50_[+2]_22 chr2:113238778-113238858 3e-05 43_[+2]_29 chr19:2977987-2978067 3e-05 23_[+2]_49 chr4:6732965-6733045 3e-05 7_[+2]_65 chr12:117111771-11711185 4.4e-05 40_[+2]_32 chr7:2903468-2903548 4.4e-05 28_[+2]_44 chr11:11032196-11032276 4.4e-05 28_[+2]_44 chr12:10902924-10903004 4.4e-05 33_[+2]_39 chr5:159546917-159546997 4.4e-05 7_[+2]_65 chr18:73555-73635 4.4e-05 20_[+2]_52 chr11:16311244-16311324 4.4e-05 44_[+2]_28 chr19:15740197-15740277 5.8e-05 47_[+2]_25 chr19:47117585-47117665 5.8e-05 38_[+2]_34 chr20:57607767-57607847 5.8e-05 24_[+2]_48 chr22:32865836-32865916 5.8e-05 20_[+2]_52 chr5:79704164-79704244 7.3e-05 53_[+2]_19 chr3:111393437-111393517 7.3e-05 33_[+2]_39 chr3:126074931-126075011 7.3e-05 62_[+2]_10 chr1:151430791-151430871 7.3e-05 52_[+2]_20 chr1:22710567-22710647 7.3e-05 7_[+2]_65 chr14:55031659-55031739 7.3e-05 31_[+2]_41 chr9:141044419-141044499 7.3e-05 34_[+2]_38 chr7:86849093-86849173 0.0001 25_[+2]_47 chr6:119862587-119862667 0.0001 59_[+2]_13 chr10:82213303-82213383 0.0001 56_[+2]_16 chr20:45152724-45152804 0.0001 42_[+2]_30 chr3:150489546-150489626 0.0001 42_[+2]_30 chr6:27562309-27562389 0.0001 67_[+2]_5 chr1:39572848-39572928 0.0001 24_[+2]_48 chr6:37184709-37184789 0.0001 44_[+2]_28 chr5:176973577-176973657 0.0001 7_[+2]_65 chr4:153494101-153494181 0.00013 37_[+2]_35 chr12:48214270-48214350 0.00013 22_[+2]_50 chr10:52153180-52153260 0.00013 10_[+2]_62 chr19:6806569-6806649 0.00013 69_[+2]_3 chr1:208418786-208418866 0.00013 27_[+2]_45 chr16:69830615-69830695 0.00013 8_[+2]_64 chr4:147262132-147262212 0.00013 45_[+2]_27 chr19:34262523-34262603 0.00013 51_[+2]_21 chr10:5624966-5625046 0.00013 28_[+2]_44 chr19:3142425-3142505 0.00014 30_[+2]_42 chr15:101818526-10181860 0.00014 40_[+2]_32 chr7:32997641-32997721 0.00014 68_[+2]_4 chr15:65394063-65394143 0.00014 44_[+2]_28 chr15:85198431-85198511 0.00016 37_[+2]_35 chr6:157615396-157615476 0.00016 30_[+2]_42 chr2:235422111-235422191 0.00016 71_[+2]_1 chr12:48591437-48591517 0.00016 23_[+2]_49 chr1:203258910-203258990 0.00017 60_[+2]_12 chr18:45938935-45939015 0.00017 25_[+2]_47 chr16:87900900-87900980 0.00017 57_[+2]_15 chr19:48103652-48103732 0.0002 16_[+2]_56 chr11:77013986-77014066 0.0002 1_[+2]_71 chr7:30510023-30510103 0.0002 38_[+2]_34 chr15:31781055-31781135 0.0002 51_[+2]_21 chr12:113795865-11379594 0.0002 19_[+2]_53 chr7:1572490-1572570 0.0002 14_[+2]_58 chr22:22973916-22973996 0.0002 37_[+2]_35 chr22:18403149-18403229 0.0002 23_[+2]_49 chr14:24802870-24802950 0.0002 40_[+2]_32 chr22:19559057-19559137 0.0002 30_[+2]_42 chr3:112281208-112281288 0.0002 25_[+2]_47 chr12:7104230-7104310 0.0002 4_[+2]_68 chr1:39598791-39598871 0.0002 26_[+2]_46 chr1:53410373-53410453 0.0002 33_[+2]_39 chr11:93275650-93275730 0.0002 47_[+2]_25 chr1:201083332-201083412 0.0002 16_[+2]_56 chr11:47536964-47537044 0.00023 55_[+2]_17 chr22:20827560-20827640 0.00031 18_[+2]_54 chr17:42084542-42084622 0.00034 2_[+2]_70 chr10:126277550-12627763 0.00038 15_[+2]_57 chr1:110431762-110431842 0.00038 35_[+2]_37 chr19:52692733-52692813 0.00042 60_[+2]_12 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AATCWSDG MEME-2 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF AATCWSDG width=8 seqs=75 chr1:20848892-20848972 ( 31) AATCTCGG 1 chr11:118936158-11893623 ( 58) AATCTCGG 1 chr16:15982846-15982926 ( 51) AATCTGGG 1 chr2:113238778-113238858 ( 44) AATCTGGG 1 chr19:2977987-2978067 ( 24) AATCTGGG 1 chr4:6732965-6733045 ( 8) AATCTGGG 1 chr12:117111771-11711185 ( 41) AATCTCTG 1 chr7:2903468-2903548 ( 29) AATCTCTG 1 chr11:11032196-11032276 ( 29) AATCTCTG 1 chr12:10902924-10903004 ( 34) AATCTCTG 1 chr5:159546917-159546997 ( 8) AATCTCTG 1 chr18:73555-73635 ( 21) AATCTCTG 1 chr11:16311244-16311324 ( 45) AATCTCTG 1 chr19:15740197-15740277 ( 48) AATCTGTG 1 chr19:47117585-47117665 ( 39) AATCTGTG 1 chr20:57607767-57607847 ( 25) AATCTGTG 1 chr22:32865836-32865916 ( 21) AATCTGTG 1 chr5:79704164-79704244 ( 54) AATCACGG 1 chr3:111393437-111393517 ( 34) AATCACGG 1 chr3:126074931-126075011 ( 63) AATCACGG 1 chr1:151430791-151430871 ( 53) AATCACGG 1 chr1:22710567-22710647 ( 8) AATCACGG 1 chr14:55031659-55031739 ( 32) AATCACGG 1 chr9:141044419-141044499 ( 35) AATCACGG 1 chr7:86849093-86849173 ( 26) AATCTCAG 1 chr6:119862587-119862667 ( 60) AATCTCAG 1 chr10:82213303-82213383 ( 57) AATCTCAG 1 chr20:45152724-45152804 ( 43) AATCTCAG 1 chr3:150489546-150489626 ( 43) AATCTCAG 1 chr6:27562309-27562389 ( 68) AATCTCAG 1 chr1:39572848-39572928 ( 25) AATCTCAG 1 chr6:37184709-37184789 ( 45) AATCTCAG 1 chr5:176973577-176973657 ( 8) AATCTCAG 1 chr4:153494101-153494181 ( 38) AATCACTG 1 chr12:48214270-48214350 ( 23) AATCACTG 1 chr10:52153180-52153260 ( 11) AATCACTG 1 chr19:6806569-6806649 ( 70) AATCACTG 1 chr1:208418786-208418866 ( 28) AATCACTG 1 chr16:69830615-69830695 ( 9) AATCACTG 1 chr4:147262132-147262212 ( 46) AATCACTG 1 chr19:34262523-34262603 ( 52) AATCTGAG 1 chr10:5624966-5625046 ( 29) AATCACTG 1 chr19:3142425-3142505 ( 31) AATCAGTG 1 chr15:101818526-10181860 ( 41) AATCAGTG 1 chr7:32997641-32997721 ( 69) AATCAGTG 1 chr15:65394063-65394143 ( 45) AATCAGTG 1 chr15:85198431-85198511 ( 38) AATCACAG 1 chr6:157615396-157615476 ( 31) AATCACAG 1 chr2:235422111-235422191 ( 72) AATCACAG 1 chr12:48591437-48591517 ( 24) AATCACAG 1 chr1:203258910-203258990 ( 61) AATCAGAG 1 chr18:45938935-45939015 ( 26) AATCAGAG 1 chr16:87900900-87900980 ( 58) AATCAGAG 1 chr19:48103652-48103732 ( 17) AATCTGGC 1 chr11:77013986-77014066 ( 2) AATCTGGC 1 chr7:30510023-30510103 ( 39) AATCTGGC 1 chr15:31781055-31781135 ( 52) AATCTGGC 1 chr12:113795865-11379594 ( 20) AATCTGGC 1 chr7:1572490-1572570 ( 15) AATCTGGC 1 chr22:22973916-22973996 ( 38) AATCTGGC 1 chr22:18403149-18403229 ( 24) AATCTGGC 1 chr14:24802870-24802950 ( 41) AATCTGGC 1 chr22:19559057-19559137 ( 31) AATCTGGC 1 chr3:112281208-112281288 ( 26) AATCTGGC 1 chr12:7104230-7104310 ( 5) AATCTGGC 1 chr1:39598791-39598871 ( 27) AATCTGGC 1 chr1:53410373-53410453 ( 34) AATCTGGC 1 chr11:93275650-93275730 ( 48) AATCTGGC 1 chr1:201083332-201083412 ( 17) AATCTGGC 1 chr11:47536964-47537044 ( 56) AATCTGTC 1 chr22:20827560-20827640 ( 19) AATCTAGG 1 chr17:42084542-42084622 ( 3) AATCTATG 1 chr10:126277550-12627763 ( 16) AATCAAGG 1 chr1:110431762-110431842 ( 36) AATCAAGG 1 chr19:52692733-52692813 ( 61) AATCAAAG 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AATCWSDG MEME-2 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 9.3564 E= 7.7e-036 207 -1287 -1287 -1287 207 -1287 -1287 -1287 -1287 -1287 -1287 205 -1287 194 -1287 -1287 70 -1287 -1287 135 -183 92 76 -1287 1 -1287 71 47 -1287 -20 157 -1287 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AATCWSDG MEME-2 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 75 E= 7.7e-036 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 0.386667 0.000000 0.000000 0.613333 0.066667 0.493333 0.440000 0.000000 0.240000 0.000000 0.426667 0.333333 0.000000 0.226667 0.773333 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AATCWSDG MEME-2 regular expression -------------------------------------------------------------------------------- AATC[TA][CG][GTA][GC] -------------------------------------------------------------------------------- Time 8.77 secs. ******************************************************************************** ******************************************************************************** MOTIF ACACACAC MEME-3 width = 8 sites = 17 llr = 158 E-value = 5.7e+002 ******************************************************************************** -------------------------------------------------------------------------------- Motif ACACACAC MEME-3 Description -------------------------------------------------------------------------------- Simplified A a1a:8:9: pos.-specific C :9:829:a probability G :::::11: matrix T :::2:::: bits 2.1 * * 1.9 * * * 1.7 * * *** 1.5 *** *** Relative 1.2 ******** Entropy 1.0 ******** (13.4 bits) 0.8 ******** 0.6 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel ACACACAC consensus C sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ACACACAC MEME-3 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr12:117111771-11711185 16 1.49e-05 gtttccaaga acacacac ccataaacct chr3:124714313-124714393 62 1.49e-05 GATTTAGAAA ACACACAC TCCTCTATCC chr19:36310996-36311076 8 1.49e-05 cacacac acacacac atgctcattc chr1:226296960-226297040 23 1.49e-05 aacttctcct acacacac atttcatatc chr2:9893557-9893637 48 1.49e-05 acacacacac acacacac aGCCTGCCTG chr11:68625290-68625370 50 1.49e-05 acacacacac acacacac acacgagatg chr12:48214270-48214350 57 1.49e-05 TGGCACCCCC ACACACAC ACCATGCCTG chr20:31169139-31169219 34 1.49e-05 AGCCTTTGTC ACACACAC CCAGAAAAGC chr4:4576691-4576771 30 1.49e-05 acacacacac acacacac acacacCAGT chr1:15116008-15116088 15 3.12e-05 ATCTATCGGG ACACCCAC CAGTCGGGAC chr22:26143545-26143625 64 3.12e-05 TCTCATAGAA ACACCCAC TGCATGATT chr1:29220460-29220540 59 5.85e-05 CCTACCAATT AAACACAC TGGGTGCTGA chr19:55166475-55166555 41 8.85e-05 AGACCCGGCT ACATCCAC CTGACTGTTT chr1:39598791-39598871 10 8.85e-05 GACTGAGTG ACACAGAC TGGGACAGGA chr2:145282391-145282471 62 8.85e-05 TTGTTTCTTA ACATCCAC TCTTCTCCCT chr7:32997641-32997721 45 1.05e-04 CAGCGCATGG ACACACGC AAAATCAGTG chr12:48591437-48591517 55 1.32e-04 ATAGGAAAGT AAATACAC TCTAAAACAA -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ACACACAC MEME-3 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr12:117111771-11711185 1.5e-05 15_[+3]_57 chr3:124714313-124714393 1.5e-05 61_[+3]_11 chr19:36310996-36311076 1.5e-05 7_[+3]_65 chr1:226296960-226297040 1.5e-05 22_[+3]_50 chr2:9893557-9893637 1.5e-05 47_[+3]_25 chr11:68625290-68625370 1.5e-05 49_[+3]_23 chr12:48214270-48214350 1.5e-05 56_[+3]_16 chr20:31169139-31169219 1.5e-05 33_[+3]_39 chr4:4576691-4576771 1.5e-05 29_[+3]_43 chr1:15116008-15116088 3.1e-05 14_[+3]_58 chr22:26143545-26143625 3.1e-05 63_[+3]_9 chr1:29220460-29220540 5.9e-05 58_[+3]_14 chr19:55166475-55166555 8.8e-05 40_[+3]_32 chr1:39598791-39598871 8.8e-05 9_[+3]_63 chr2:145282391-145282471 8.8e-05 61_[+3]_11 chr7:32997641-32997721 0.0001 44_[+3]_28 chr12:48591437-48591517 0.00013 54_[+3]_18 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ACACACAC MEME-3 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF ACACACAC width=8 seqs=17 chr12:117111771-11711185 ( 16) ACACACAC 1 chr3:124714313-124714393 ( 62) ACACACAC 1 chr19:36310996-36311076 ( 8) ACACACAC 1 chr1:226296960-226297040 ( 23) ACACACAC 1 chr2:9893557-9893637 ( 48) ACACACAC 1 chr11:68625290-68625370 ( 50) ACACACAC 1 chr12:48214270-48214350 ( 57) ACACACAC 1 chr20:31169139-31169219 ( 34) ACACACAC 1 chr4:4576691-4576771 ( 30) ACACACAC 1 chr1:15116008-15116088 ( 15) ACACCCAC 1 chr22:26143545-26143625 ( 64) ACACCCAC 1 chr1:29220460-29220540 ( 59) AAACACAC 1 chr19:55166475-55166555 ( 41) ACATCCAC 1 chr1:39598791-39598871 ( 10) ACACAGAC 1 chr2:145282391-145282471 ( 62) ACATCCAC 1 chr7:32997641-32997721 ( 45) ACACACGC 1 chr12:48591437-48591517 ( 55) AAATACAC 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ACACACAC MEME-3 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 10.8621 E= 5.7e+002 207 -1073 -1073 -1073 -101 176 -1073 -1073 207 -1073 -1073 -1073 -1073 166 -1073 -45 168 -15 -1073 -1073 -1073 185 -214 -1073 198 -1073 -214 -1073 -1073 194 -1073 -1073 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ACACACAC MEME-3 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 17 E= 5.7e+002 1.000000 0.000000 0.000000 0.000000 0.117647 0.882353 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.823529 0.000000 0.176471 0.764706 0.235294 0.000000 0.000000 0.000000 0.941176 0.058824 0.000000 0.941176 0.000000 0.058824 0.000000 0.000000 1.000000 0.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ACACACAC MEME-3 regular expression -------------------------------------------------------------------------------- ACAC[AC]CAC -------------------------------------------------------------------------------- Time 12.28 secs. ******************************************************************************** ******************************************************************************** MOTIF YAGAATAA MEME-4 width = 8 sites = 10 llr = 103 E-value = 5.5e+002 ******************************************************************************** -------------------------------------------------------------------------------- Motif YAGAATAA MEME-4 Description -------------------------------------------------------------------------------- Simplified A :a:aa1aa pos.-specific C 4::::::: probability G ::a::::: matrix T 6::::9:: bits 2.1 * ** ** 1.9 **** ** 1.7 ******* 1.5 ******* Relative 1.2 ******* Entropy 1.0 ******** (14.9 bits) 0.8 ******** 0.6 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel TAGAATAA consensus C sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YAGAATAA MEME-4 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr7:76012516-76012596 39 1.15e-05 tcatcatctt tagaataa aacgcctccc chr2:39697153-39697233 61 1.15e-05 ATATTGAGCC TAGAATAA AGCACAGAAT chr5:159546917-159546997 28 1.15e-05 CAGAGATCCT TAGAATAA ATGTTATTTC chr11:96037328-96037408 72 1.15e-05 TCTCACCCCT TAGAATAA G chr6:44365640-44365720 60 1.15e-05 ATTCAGGCCC TAGAATAA CCTCCCTATC chr6:130539371-130539451 50 2.40e-05 gttcccacac cagaataa gaagggccag chr2:47629567-47629647 58 2.40e-05 agaatgtaag cagaataa aggcagtgat chr1:207872343-207872423 49 2.40e-05 GTGATTTTTC CAGAATAA CGTAGCCTGT chr1:207738994-207739074 47 2.40e-05 GTGATTTTTC CAGAATAA GGTAGCCTGT chr9:38062702-38062782 6 3.54e-05 gagac tagaaaaa tgactcagAT -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YAGAATAA MEME-4 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr7:76012516-76012596 1.2e-05 38_[+4]_34 chr2:39697153-39697233 1.2e-05 60_[+4]_12 chr5:159546917-159546997 1.2e-05 27_[+4]_45 chr11:96037328-96037408 1.2e-05 71_[+4]_1 chr6:44365640-44365720 1.2e-05 59_[+4]_13 chr6:130539371-130539451 2.4e-05 49_[+4]_23 chr2:47629567-47629647 2.4e-05 57_[+4]_15 chr1:207872343-207872423 2.4e-05 48_[+4]_24 chr1:207738994-207739074 2.4e-05 46_[+4]_26 chr9:38062702-38062782 3.5e-05 5_[+4]_67 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YAGAATAA MEME-4 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF YAGAATAA width=8 seqs=10 chr7:76012516-76012596 ( 39) TAGAATAA 1 chr2:39697153-39697233 ( 61) TAGAATAA 1 chr5:159546917-159546997 ( 28) TAGAATAA 1 chr11:96037328-96037408 ( 72) TAGAATAA 1 chr6:44365640-44365720 ( 60) TAGAATAA 1 chr6:130539371-130539451 ( 50) CAGAATAA 1 chr2:47629567-47629647 ( 58) CAGAATAA 1 chr1:207872343-207872423 ( 49) CAGAATAA 1 chr1:207738994-207739074 ( 47) CAGAATAA 1 chr9:38062702-38062782 ( 6) TAGAAAAA 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YAGAATAA MEME-4 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 11.0846 E= 5.5e+002 -997 62 -997 132 207 -997 -997 -997 -997 -997 194 -997 207 -997 -997 -997 207 -997 -997 -997 -125 -997 -997 190 207 -997 -997 -997 207 -997 -997 -997 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YAGAATAA MEME-4 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 10 E= 5.5e+002 0.000000 0.400000 0.000000 0.600000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.100000 0.000000 0.000000 0.900000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YAGAATAA MEME-4 regular expression -------------------------------------------------------------------------------- [TC]AGAATAA -------------------------------------------------------------------------------- Time 15.76 secs. ******************************************************************************** ******************************************************************************** MOTIF AAAAGAAA MEME-5 width = 8 sites = 2 llr = 23 E-value = 1.0e+005 ******************************************************************************** -------------------------------------------------------------------------------- Motif AAAAGAAA MEME-5 Description -------------------------------------------------------------------------------- Simplified A aaaa:aaa pos.-specific C :::::::: probability G ::::a::: matrix T :::::::: bits 2.1 **** *** 1.9 ******** 1.7 ******** 1.5 ******** Relative 1.2 ******** Entropy 1.0 ******** (16.4 bits) 0.8 ******** 0.6 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel AAAAGAAA consensus sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAAAGAAA MEME-5 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr22:22652920-22653000 51 1.12e-05 CCATGGTGAG AAAAGAAA GCGCAGAGAG chr1:151430791-151430871 70 1.12e-05 GCGCCATCCC AAAAGAAA TTT -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAAAGAAA MEME-5 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr22:22652920-22653000 1.1e-05 50_[+5]_22 chr1:151430791-151430871 1.1e-05 69_[+5]_3 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAAAGAAA MEME-5 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF AAAAGAAA width=8 seqs=2 chr22:22652920-22653000 ( 51) AAAAGAAA 1 chr1:151430791-151430871 ( 70) AAAAGAAA 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAAAGAAA MEME-5 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 13.1555 E= 1.0e+005 207 -765 -765 -765 207 -765 -765 -765 207 -765 -765 -765 207 -765 -765 -765 -765 -765 194 -765 207 -765 -765 -765 207 -765 -765 -765 207 -765 -765 -765 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAAAGAAA MEME-5 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 2 E= 1.0e+005 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAAAGAAA MEME-5 regular expression -------------------------------------------------------------------------------- AAAAGAAA -------------------------------------------------------------------------------- Time 19.23 secs. ******************************************************************************** ******************************************************************************** SUMMARY OF MOTIFS ******************************************************************************** -------------------------------------------------------------------------------- Combined block diagrams: non-overlapping sites with p-value < 0.0001 -------------------------------------------------------------------------------- SEQUENCE NAME COMBINED P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr12:95609919-95609999 1.25e-01 80 chr14:93651878-93651958 8.02e-01 80 chr1:207738994-207739074 8.16e-03 46_[+4(2.40e-05)]_26 chr11:75274438-75274518 3.03e-01 80 chr17:44842544-44842624 9.23e-03 80 chr1:6300647-6300727 7.61e-02 68_[+1(6.82e-05)]_4 chr8:8920939-8921019 8.44e-01 80 chr9:34701883-34701963 3.75e-01 80 chr9:46210544-46210624 1.75e-02 80 chr1:156635013-156635093 5.39e-01 80 chr15:52093808-52093888 6.68e-04 80 chr4:6732965-6733045 1.55e-01 7_[+2(3.02e-05)]_65 chr2:145282391-145282471 1.59e-01 61_[+3(8.85e-05)]_11 chr13:25588858-25588938 2.50e-03 80 chr4:4576691-4576771 4.95e-03 13_[+3(1.49e-05)]_[+3(1.49e-05)]_\ [+3(1.49e-05)]_43 chr10:65226289-65226369 1.73e-02 23_[+1(6.82e-05)]_49 chr7:86849972-86850052 6.50e-01 80 chr3:49838767-49838847 8.60e-02 62_[+1(4.12e-05)]_10 chr1:201083332-201083412 2.48e-01 80 chr19:35581243-35581323 7.15e-01 80 chr3:193886278-193886358 9.13e-01 80 chr11:93275650-93275730 2.02e-01 80 chr1:93914778-93914858 4.46e-01 80 chr12:95848884-95848964 3.03e-02 66_[+1(2.83e-05)]_6 chr14:75389950-75390030 9.87e-01 80 chr12:48591437-48591517 4.94e-05 17_[+5(4.33e-05)]_55 chr3:167812527-167812607 6.65e-01 80 chr9:141044419-141044499 7.57e-04 34_[+2(7.32e-05)]_38 chr8:61566213-61566293 8.43e-01 80 chr22:19869471-19869551 1.79e-01 80 chr9:115249995-115250075 7.92e-02 80 chrX:2610417-2610497 3.47e-01 80 chr1:53410373-53410453 1.28e-02 80 chr14:55031659-55031739 4.57e-03 31_[+2(7.32e-05)]_7_[+1(2.83e-05)]_\ 26 chr21:46974749-46974829 3.98e-01 80 chr10:5624966-5625046 1.26e-02 80 chr1:39598791-39598871 4.96e-04 9_[+3(8.85e-05)]_20_[+1(2.83e-05)]_\ 35 chr1:207872343-207872423 7.37e-03 48_[+4(2.40e-05)]_24 chr1:9844804-9844884 6.46e-01 80 chr7:100199877-100199957 9.95e-01 80 chr12:7104230-7104310 5.07e-01 80 chr22:29138395-29138475 4.51e-01 80 chr22:26143545-26143625 3.52e-04 63_[+3(3.12e-05)]_9 chr1:22710567-22710647 9.50e-02 7_[+2(7.32e-05)]_65 chr10:60026695-60026775 5.28e-01 80 chr17:27388172-27388252 2.29e-01 80 chr12:117627564-11762764 6.40e-03 50_[+1(2.83e-05)]_22 chr2:148602391-148602471 6.68e-02 80 chr7:99766126-99766206 5.04e-01 80 chr2:242295475-242295555 2.12e-01 26_[+1(6.82e-05)]_46 chr8:95007023-95007103 1.15e-01 80 chr10:72647900-72647980 2.09e-01 80 chr20:31170716-31170796 6.27e-01 80 chr1:113216380-113216460 1.93e-01 80 chr1:16824086-16824166 1.96e-02 14_[+1(2.83e-05)]_58 chr3:112281208-112281288 1.83e-01 80 chr6:30181204-30181284 3.07e-01 20_[+1(9.53e-05)]_52 chr22:19559057-19559137 2.15e-01 80 chr19:34262523-34262603 4.04e-01 80 chr17:1532126-1532206 1.33e-02 80 chrX:53285637-53285717 3.90e-01 80 chr19:49933649-49933729 7.64e-01 80 chr3:155581218-155581298 3.62e-02 80 chr16:56761023-56761103 1.51e-02 80 chr4:147262132-147262212 6.07e-04 13_[+5(4.33e-05)]_39_[+5(4.33e-05)]_\ 12 chr11:16311244-16311324 8.39e-03 44_[+2(4.43e-05)]_28 chr6:150186165-150186245 1.39e-03 80 chr22:32865836-32865916 2.04e-02 20_[+2(5.83e-05)]_52 chr9:139872713-139872793 8.21e-01 80 chr17:27276229-27276309 6.84e-03 80 chr6:44365640-44365720 1.00e-02 59_[+4(1.15e-05)]_13 chr9:133356119-133356199 4.39e-01 80 chr1:206807817-206807897 4.68e-01 80 chr6:27689262-27689342 8.20e-02 80 chr1:207155749-207155829 6.74e-01 80 chr11:46143409-46143489 2.77e-01 80 chr16:50188937-50189017 1.90e-01 80 chr15:96870660-96870740 1.71e-01 43_[+1(9.53e-05)]_29 chr10:111969049-11196912 9.37e-02 80 chr1:151430791-151430871 1.88e-04 18_[+5(4.33e-05)]_26_[+2(7.32e-05)]_\ 9_[+5(1.12e-05)]_3 chr1:29220460-29220540 1.27e-03 58_[+3(5.85e-05)]_14 chr16:69830615-69830695 7.19e-02 80 chr2:103235206-103235286 8.74e-01 80 chr18:73555-73635 2.95e-03 20_[+2(4.43e-05)]_28_[+1(6.82e-05)]_\ 16 chr1:27190800-27190880 9.99e-01 80 chr22:22652920-22653000 4.09e-02 50_[+5(1.12e-05)]_22 chr9:71293505-71293585 3.18e-01 80 chr7:72350487-72350567 6.70e-01 80 chr5:176973577-176973657 1.59e-02 80 chr18:11981113-11981193 2.18e-01 50_[+1(4.12e-05)]_22 chr22:42476343-42476423 4.79e-01 80 chr3:126074931-126075011 1.42e-01 62_[+2(7.32e-05)]_10 chr11:118936158-11893623 1.53e-02 57_[+2(1.52e-05)]_15 chr1:148556806-148556886 2.77e-01 80 chr8:143808009-143808089 1.46e-01 15_[+1(6.82e-05)]_57 chr6:37184709-37184789 1.69e-03 38_[+5(4.33e-05)]_34 chr1:39572848-39572928 7.87e-02 80 chr2:220341178-220341258 1.27e-01 54_[+1(1.42e-05)]_18 chr1:200708272-200708352 4.02e-01 80 chr10:45454729-45454809 5.33e-01 80 chr11:96037328-96037408 3.02e-03 71_[+4(1.15e-05)]_1 chr3:111393437-111393517 2.50e-01 33_[+2(7.32e-05)]_39 chr18:68004556-68004636 3.85e-01 80 chr6:27562309-27562389 6.48e-04 80 chr20:57607767-57607847 9.47e-03 24_[+2(5.83e-05)]_48 chr8:144852561-144852641 3.33e-01 80 chr16:71518008-71518088 1.46e-02 57_[+1(2.83e-05)]_15 chr19:3013024-3013104 3.63e-01 80 chr19:2977987-2978067 2.30e-01 23_[+2(3.02e-05)]_49 chr16:87900900-87900980 4.02e-04 51_[+5(1.12e-05)]_21 chr15:41196373-41196453 1.72e-01 80 chr20:31169139-31169219 1.87e-03 33_[+3(1.49e-05)]_39 chr14:24802870-24802950 7.82e-02 80 chr22:32332393-32332473 6.63e-01 80 chr17:77776903-77776983 9.97e-01 80 chr20:30517566-30517646 1.77e-01 80 chr5:159546917-159546997 1.96e-04 7_[+2(4.43e-05)]_12_[+4(1.15e-05)]_\ 45 chr9:38062702-38062782 6.49e-03 5_[+4(3.54e-05)]_67 chr2:113238778-113238858 7.05e-02 43_[+2(3.02e-05)]_29 chr1:208418786-208418866 1.14e-02 80 chr19:18303065-18303145 8.32e-01 80 chr17:46092135-46092215 2.92e-01 80 chr1:93546102-93546182 3.55e-01 80 chr18:45938935-45939015 4.05e-03 80 chr19:6806569-6806649 8.08e-02 80 chr3:150489546-150489626 5.04e-03 80 chr21:36356292-36356372 1.46e-01 80 chr22:18403149-18403229 4.26e-01 80 chr17:42084542-42084622 4.71e-01 80 chr22:22973916-22973996 2.51e-01 80 chr2:39697153-39697233 2.56e-05 21_[+1(4.12e-05)]_31_[+4(1.15e-05)]_\ 12 chr19:55166475-55166555 2.57e-01 8_[+3(8.85e-05)]_24_[+3(8.85e-05)]_\ 32 chr12:10902924-10903004 9.07e-02 33_[+2(4.43e-05)]_39 chr1:39007019-39007099 1.40e-02 80 chr4:8601548-8601628 1.66e-01 80 chr11:74203979-74204059 6.12e-01 80 chr6:86353829-86353909 1.01e-01 60_[+1(2.83e-05)]_12 chr20:45152724-45152804 3.23e-03 80 chr22:42665534-42665614 1.03e-01 80 chr16:15982846-15982926 3.18e-02 50_[+2(3.02e-05)]_22 chr1:114224722-114224802 1.38e-01 55_[+1(4.12e-05)]_17 chr5:79704164-79704244 3.04e-01 53_[+2(7.32e-05)]_19 chr7:2392889-2392969 6.62e-01 80 chr7:5465263-5465343 9.99e-01 80 chr14:53257588-53257668 6.67e-02 80 chr1:20848892-20848972 9.84e-03 30_[+2(1.52e-05)]_8_[+2(4.43e-05)]_\ 26 chr2:47629567-47629647 9.75e-04 57_[+4(2.40e-05)]_15 chr16:438117-438197 2.15e-03 29_[+1(2.83e-05)]_43 chr15:85144444-85144524 4.66e-01 80 chr19:47117585-47117665 8.52e-02 38_[+2(5.83e-05)]_34 chr10:82213303-82213383 1.62e-02 80 chr21:34753141-34753221 2.00e-01 80 chr1:15116008-15116088 9.93e-03 14_[+3(3.12e-05)]_58 chr19:47551298-47551378 7.62e-01 80 chr9:139965077-139965157 7.33e-01 80 chr1:53166806-53166886 1.23e-01 30_[+1(6.82e-05)]_42 chr11:11032196-11032276 1.51e-02 28_[+2(4.43e-05)]_44 chr2:235422111-235422191 1.71e-01 80 chr15:65394063-65394143 5.27e-02 80 chr7:1572490-1572570 1.38e-01 80 chr3:154798185-154798265 9.41e-04 37_[+1(4.12e-05)]_35 chr12:113795865-11379594 5.85e-02 80 chr22:20827560-20827640 2.67e-01 80 chr1:23886543-23886623 1.27e-02 22_[+1(6.82e-05)]_50 chr6:157615396-157615476 1.91e-01 80 chr19:1864942-1865022 4.68e-01 80 chr7:32997641-32997721 2.24e-04 80 chr15:31781055-31781135 1.57e-01 80 chr1:40004962-40005042 5.04e-01 80 chr1:44471570-44471650 2.22e-01 44_[+1(2.83e-05)]_18_[+1(9.53e-05)]_\ 2 chr14:77428250-77428330 2.04e-02 80 chr6:119862587-119862667 4.48e-02 80 chr7:76012516-76012596 1.55e-02 38_[+4(1.15e-05)]_34 chr19:17033005-17033085 4.98e-01 80 chr1:110431762-110431842 2.81e-03 80 chr1:203258910-203258990 1.40e-01 80 chr20:30410798-30410878 5.31e-01 80 chr10:52153180-52153260 2.33e-01 80 chr19:15740197-15740277 7.27e-03 47_[+2(5.83e-05)]_25 chr6:31937575-31937655 1.73e-01 80 chr1:70033362-70033442 6.25e-02 80 chr6:26034192-26034272 3.13e-01 80 chr4:123654589-123654669 3.66e-01 80 chr10:126277550-12627763 4.66e-01 80 chr6:135505008-135505088 2.34e-01 80 chr7:100202167-100202247 6.88e-01 80 chr12:48214270-48214350 9.07e-05 13_[+1(9.53e-05)]_35_[+3(1.49e-05)]_\ 16 chr11:68625290-68625370 8.89e-02 19_[+3(1.49e-05)]_[+3(1.49e-05)]_\ [+3(1.49e-05)]_[+3(1.49e-05)]_[+3(1.49e-05)]_21 chr2:9893557-9893637 1.23e-01 29_[+3(1.49e-05)]_[+3(1.49e-05)]_\ [+3(1.49e-05)]_27 chr3:17785253-17785333 2.67e-02 46_[+1(2.83e-05)]_7_[+1(2.83e-05)]_\ 11 chr7:86849093-86849173 3.42e-01 80 chr12:68752705-68752785 2.56e-02 26_[+1(4.12e-05)]_46 chr7:30510023-30510103 1.17e-01 80 chr15:101818526-10181860 2.47e-01 80 chr19:54372299-54372379 9.95e-01 80 chr15:22834064-22834144 7.27e-02 70_[+1(4.12e-05)]_2 chr9:127632054-127632134 8.25e-01 80 chr6:130539371-130539451 6.14e-03 49_[+4(2.40e-05)]_23 chr11:12846191-12846271 5.85e-01 80 chr7:107103765-107103845 2.69e-01 80 chr19:44100189-44100269 5.61e-01 80 chr6:7389643-7389723 9.35e-01 80 chr16:70471370-70471450 1.23e-02 40_[+5(4.33e-05)]_17_[+5(4.33e-05)]_\ 7 chr2:43454508-43454588 8.92e-01 80 chr3:4866625-4866705 4.25e-03 33_[+1(2.83e-05)]_39 chr15:85198431-85198511 5.54e-03 80 chr1:1828757-1828837 1.19e-01 80 chr8:80680976-80681056 6.61e-01 80 chr19:955147-955227 4.36e-01 80 chr2:66660651-66660731 3.39e-01 38_[+1(9.53e-05)]_34 chr2:3642628-3642708 9.98e-01 80 chr11:77013986-77014066 2.14e-01 80 chr7:100202878-100202958 3.30e-01 80 chr3:195934849-195934929 9.97e-01 80 chr1:226296960-226297040 5.79e-02 22_[+3(1.49e-05)]_50 chr19:40931395-40931475 7.01e-01 80 chr19:3142425-3142505 1.33e-03 23_[+5(4.33e-05)]_13_[+5(4.33e-05)]_\ 28 chr12:95466562-95466642 2.49e-02 40_[+1(2.83e-05)]_32 chr5:95997647-95997727 2.62e-01 80 chr4:153494101-153494181 2.25e-02 80 chr6:2926285-2926365 8.47e-02 80 chr11:6378629-6378709 3.11e-01 80 chr19:48103652-48103732 1.36e-03 80 chr5:124060909-124060989 1.39e-01 80 chr7:2903468-2903548 1.45e-01 28_[+2(4.43e-05)]_44 chr10:80685764-80685844 7.29e-01 80 chr19:36195210-36195290 8.44e-01 80 chr21:35014797-35014877 9.86e-01 80 chr19:52692733-52692813 4.44e-02 80 chr19:3580163-3580243 5.82e-02 61_[+1(2.83e-05)]_11 chr11:47536964-47537044 4.14e-01 80 chr10:79165623-79165703 6.87e-01 80 chrX:24072418-24072498 1.87e-01 80 chr6:89791412-89791492 4.99e-01 80 chr20:32793449-32793529 6.06e-01 80 chr19:49141522-49141602 6.49e-02 80 chr19:36310996-36311076 5.98e-02 1_[+3(1.49e-05)]_71 chr1:205218368-205218448 2.40e-02 42_[+1(2.83e-05)]_30 chr12:107485879-10748595 3.29e-01 80 chr16:85854710-85854790 2.63e-01 80 chr3:124714313-124714393 8.04e-05 61_[+3(1.49e-05)]_11 chr19:45982483-45982563 1.24e-01 80 chr7:138759915-138759995 6.52e-01 80 chr12:117111771-11711185 9.35e-04 15_[+3(1.49e-05)]_17_[+2(4.43e-05)]_\ 32 chr6:158589697-158589777 1.65e-01 28_[+1(6.82e-05)]_44 chr19:50767940-50768020 4.73e-01 80 chr13:76056710-76056790 8.80e-01 80 chr7:116593006-116593086 1.66e-01 80 chr1:52114061-52114141 6.34e-01 80 chr2:174220029-174220109 5.10e-01 80 -------------------------------------------------------------------------------- ******************************************************************************** ******************************************************************************** Stopped because requested number of motifs (5) found. ******************************************************************************** CPU: c22n05.farnam.hpc.yale.internal ********************************************************************************