******************************************************************************** MEME - Motif discovery tool ******************************************************************************** MEME version 5.3.3 (Release date: Sun Feb 7 15:39:52 2021 -0800) For further information on how to interpret these results please access https://meme-suite.org/meme. To get a copy of the MEME Suite software please access https://meme-suite.org. ******************************************************************************** ******************************************************************************** REFERENCE ******************************************************************************** If you use this program in your research, please cite: Timothy L. Bailey and Charles Elkan, "Fitting a mixture model by expectation maximization to discover motifs in biopolymers", Proceedings of the Second International Conference on Intelligent Systems for Molecular Biology, pp. 28-36, AAAI Press, Menlo Park, California, 1994. ******************************************************************************** ******************************************************************************** TRAINING SET ******************************************************************************** PRIMARY SEQUENCES= ../result/final_prediction/K562/fasta/RankLinear0.6_40/PHF20.fasta CONTROL SEQUENCES= --none-- ALPHABET= ACGT Sequence name Weight Length Sequence name Weight Length ------------- ------ ------ ------------- ------ ------ chr17:77801103-77801183 1.0000 80 chr1:155179085-155179165 1.0000 80 chr17:36453168-36453248 1.0000 80 chr15:74392520-74392600 1.0000 80 chr9:131133705-131133785 1.0000 80 chr14:23938966-23939046 1.0000 80 chr1:42922457-42922537 1.0000 80 chr9:33076567-33076647 1.0000 80 chr2:20386449-20386529 1.0000 80 chr17:45569699-45569779 1.0000 80 chr14:68283253-68283333 1.0000 80 chr22:45128729-45128809 1.0000 80 chr2:128051580-128051660 1.0000 80 chr20:8012319-8012399 1.0000 80 chr20:18447979-18448059 1.0000 80 chr2:32502980-32503060 1.0000 80 chr3:127279266-127279346 1.0000 80 chr1:156265390-156265470 1.0000 80 chrX:101975569-101975649 1.0000 80 chrX:102809792-102809872 1.0000 80 chr7:2598540-2598620 1.0000 80 chr11:66774066-66774146 1.0000 80 chr3:127279466-127279546 1.0000 80 chr7:6865937-6866017 1.0000 80 chr17:42767030-42767110 1.0000 80 chr19:56092329-56092409 1.0000 80 chr14:23790112-23790192 1.0000 80 chr14:102149882-10214996 1.0000 80 chr16:14014133-14014213 1.0000 80 chr10:102027360-10202744 1.0000 80 chr2:61921698-61921778 1.0000 80 chr7:112580374-112580454 1.0000 80 chr12:53541142-53541222 1.0000 80 chr12:53645953-53646033 1.0000 80 chr8:30013906-30013986 1.0000 80 chr1:155188788-155188868 1.0000 80 chr17:7218745-7218825 1.0000 80 chr17:42422381-42422461 1.0000 80 chr1:151735902-151735982 1.0000 80 chr3:195426117-195426197 1.0000 80 chr5:1345357-1345437 1.0000 80 chrX:48659877-48659957 1.0000 80 chr14:71067290-71067370 1.0000 80 chr3:66271487-66271567 1.0000 80 chr16:5083856-5083936 1.0000 80 chr1:155211017-155211097 1.0000 80 chr16:16177770-16177850 1.0000 80 chrX:102024111-102024191 1.0000 80 chr15:42500355-42500435 1.0000 80 chr7:30155363-30155443 1.0000 80 chr2:68290051-68290131 1.0000 80 chr17:40976189-40976269 1.0000 80 chr12:39932573-39932653 1.0000 80 chr16:69796070-69796150 1.0000 80 chr19:18747917-18747997 1.0000 80 chr14:75179829-75179909 1.0000 80 chr22:19615313-19615393 1.0000 80 chr10:51827657-51827737 1.0000 80 chr11:6640590-6640670 1.0000 80 chr9:99776071-99776151 1.0000 80 chr19:9649231-9649311 1.0000 80 chr1:7887471-7887551 1.0000 80 chr13:114103560-11410364 1.0000 80 chr3:75834523-75834603 1.0000 80 chr9:125675519-125675599 1.0000 80 chr14:55878453-55878533 1.0000 80 chr4:37003435-37003515 1.0000 80 chr17:56709487-56709567 1.0000 80 chr11:94227238-94227318 1.0000 80 chr22:26908381-26908461 1.0000 80 chr1:241987387-241987467 1.0000 80 chr16:69556889-69556969 1.0000 80 chr4:148538592-148538672 1.0000 80 chr12:114184986-11418506 1.0000 80 chr13:49684334-49684414 1.0000 80 chr1:7831373-7831453 1.0000 80 chr10:26986390-26986470 1.0000 80 chr8:48173254-48173334 1.0000 80 chr4:100815466-100815546 1.0000 80 chr6:10723082-10723162 1.0000 80 chr1:25031788-25031868 1.0000 80 chr19:55663507-55663587 1.0000 80 chr12:101673985-10167406 1.0000 80 chrX:130037025-130037105 1.0000 80 chr7:1199798-1199878 1.0000 80 chr13:64650069-64650149 1.0000 80 chr13:111805829-11180590 1.0000 80 chr6:148466267-148466347 1.0000 80 chr15:63413811-63413891 1.0000 80 chr20:2644835-2644915 1.0000 80 chr4:6727464-6727544 1.0000 80 chr15:89010455-89010535 1.0000 80 chr5:93447399-93447479 1.0000 80 chr2:143688671-143688751 1.0000 80 chr7:149034-149114 1.0000 80 chr2:27851948-27852028 1.0000 80 chr15:65426182-65426262 1.0000 80 chr13:45563676-45563756 1.0000 80 chr22:24336008-24336088 1.0000 80 chr4:6576966-6577046 1.0000 80 chr15:75628371-75628451 1.0000 80 chr3:15469084-15469164 1.0000 80 chr12:131239198-13123927 1.0000 80 chr14:74551717-74551797 1.0000 80 chr11:107436327-10743640 1.0000 80 chr8:37605543-37605623 1.0000 80 chr19:51373847-51373927 1.0000 80 chr4:6727669-6727749 1.0000 80 chr13:32889461-32889541 1.0000 80 chr19:8617796-8617876 1.0000 80 chr3:119396033-119396113 1.0000 80 chr1:143467499-143467579 1.0000 80 chr6:107077473-107077553 1.0000 80 chr16:70834994-70835074 1.0000 80 chr8:146277879-146277959 1.0000 80 chr21:45395087-45395167 1.0000 80 chr2:85581961-85582041 1.0000 80 chr10:15902615-15902695 1.0000 80 chr4:177116901-177116981 1.0000 80 chr11:94706611-94706691 1.0000 80 chr7:45808654-45808734 1.0000 80 chr10:113943488-11394356 1.0000 80 chr15:74988326-74988406 1.0000 80 chr6:5261779-5261859 1.0000 80 chr18:1509005-1509085 1.0000 80 chr1:236030456-236030536 1.0000 80 chr20:5093644-5093724 1.0000 80 chr16:89283918-89283998 1.0000 80 chr7:111846817-111846897 1.0000 80 chr8:182443-182523 1.0000 80 chr1:203652043-203652123 1.0000 80 chr10:103825178-10382525 1.0000 80 chr14:23775949-23776029 1.0000 80 chr17:73258044-73258124 1.0000 80 chr5:28809228-28809308 1.0000 80 chr19:34012568-34012648 1.0000 80 chr17:21427518-21427598 1.0000 80 chr10:127408351-12740843 1.0000 80 chr11:66206166-66206246 1.0000 80 chr6:116574637-116574717 1.0000 80 chr9:131267125-131267205 1.0000 80 chr14:100150138-10015021 1.0000 80 chr2:175260310-175260390 1.0000 80 chr20:55926375-55926455 1.0000 80 chr1:154600493-154600573 1.0000 80 chr2:96068448-96068528 1.0000 80 chr3:124449318-124449398 1.0000 80 chr8:144623753-144623833 1.0000 80 chr19:32836569-32836649 1.0000 80 chr5:132362047-132362127 1.0000 80 chr2:3605810-3605890 1.0000 80 chr5:78908376-78908456 1.0000 80 chr6:52463188-52463268 1.0000 80 chr13:52768537-52768617 1.0000 80 chr6:71122828-71122908 1.0000 80 chr3:122101941-122102021 1.0000 80 chr11:28131808-28131888 1.0000 80 chr19:11639822-11639902 1.0000 80 chr6:33388961-33389041 1.0000 80 chr10:75910441-75910521 1.0000 80 chr7:102212874-102212954 1.0000 80 chr7:99069299-99069379 1.0000 80 chr12:42719932-42720012 1.0000 80 chr13:103498046-10349812 1.0000 80 chr20:45810037-45810117 1.0000 80 chr3:47462769-47462849 1.0000 80 chr15:75165521-75165601 1.0000 80 chr1:45477764-45477844 1.0000 80 chr5:139682544-139682624 1.0000 80 chr9:99983961-99984041 1.0000 80 chr12:66524430-66524510 1.0000 80 chr9:34049045-34049125 1.0000 80 chr15:62682446-62682526 1.0000 80 chr3:194047454-194047534 1.0000 80 chr13:53191601-53191681 1.0000 80 chr16:1020816-1020896 1.0000 80 chr16:25118474-25118554 1.0000 80 chr4:107237475-107237555 1.0000 80 chr6:10747698-10747778 1.0000 80 chr17:21454550-21454630 1.0000 80 chr16:5121849-5121929 1.0000 80 chr11:66112491-66112571 1.0000 80 chr14:69291620-69291700 1.0000 80 chr16:3156455-3156535 1.0000 80 chr17:38210561-38210641 1.0000 80 chr9:97136543-97136623 1.0000 80 chr6:28220010-28220090 1.0000 80 chr11:36310897-36310977 1.0000 80 chr15:49462086-49462166 1.0000 80 chr11:69489992-69490072 1.0000 80 chr12:121454166-12145424 1.0000 80 chr10:120101707-12010178 1.0000 80 chr14:32030638-32030718 1.0000 80 chr9:86323001-86323081 1.0000 80 chr4:152682081-152682161 1.0000 80 chr9:6015565-6015645 1.0000 80 chr1:70671299-70671379 1.0000 80 chr7:38948698-38948778 1.0000 80 chr9:140100171-140100251 1.0000 80 chr17:1227594-1227674 1.0000 80 chr19:18132983-18133063 1.0000 80 chr2:108364809-108364889 1.0000 80 chr12:65153132-65153212 1.0000 80 chr3:158519790-158519870 1.0000 80 chr7:6617179-6617259 1.0000 80 chr16:86588767-86588847 1.0000 80 chr3:53164370-53164450 1.0000 80 chr16:57219747-57219827 1.0000 80 chr17:73663263-73663343 1.0000 80 chr19:51728323-51728403 1.0000 80 chr1:32110245-32110325 1.0000 80 chr1:762766-762846 1.0000 80 chr12:69864153-69864233 1.0000 80 chr19:44100604-44100684 1.0000 80 chr8:146078294-146078374 1.0000 80 chr7:23145248-23145328 1.0000 80 chr16:71496087-71496167 1.0000 80 chr16:48644231-48644311 1.0000 80 chr3:194048462-194048542 1.0000 80 chr19:10426575-10426655 1.0000 80 chr19:41331480-41331560 1.0000 80 chr20:37591035-37591115 1.0000 80 chr16:70333144-70333224 1.0000 80 chr22:46957478-46957558 1.0000 80 chr5:137548849-137548929 1.0000 80 chr14:50583234-50583314 1.0000 80 chr7:100728841-100728921 1.0000 80 chr2:113931365-113931445 1.0000 80 chr20:16710646-16710726 1.0000 80 chr13:41345308-41345388 1.0000 80 chr3:58292026-58292106 1.0000 80 chr18:29671690-29671770 1.0000 80 chr9:99329330-99329410 1.0000 80 chr13:21476745-21476825 1.0000 80 chr20:61408503-61408583 1.0000 80 chr11:130786211-13078629 1.0000 80 chr18:12703043-12703123 1.0000 80 chr2:237994510-237994590 1.0000 80 chr7:26904493-26904573 1.0000 80 chr17:26684646-26684726 1.0000 80 chr13:26796481-26796561 1.0000 80 chr10:114206804-11420688 1.0000 80 chr14:24912131-24912211 1.0000 80 chr4:119606420-119606500 1.0000 80 chr16:58718582-58718662 1.0000 80 chr10:17428819-17428899 1.0000 80 chr2:219536546-219536626 1.0000 80 chr2:183943478-183943558 1.0000 80 chr15:40861512-40861592 1.0000 80 chr12:133657594-13365767 1.0000 80 ******************************************************************************** ******************************************************************************** COMMAND LINE SUMMARY ******************************************************************************** This information can also be useful in the event you wish to report a problem with the MEME software. command: meme -oc ../result/final_prediction/K562/inference_raw/MEME/RankLinear0.6_40_PHF20/ -dna -nmotifs 5 -w 8 -maxsize 250000 -nostatus ../result/final_prediction/K562/fasta/RankLinear0.6_40/PHF20.fasta model: mod= zoops nmotifs= 5 evt= inf objective function: em= E-value of product of p-values starts= E-value of product of p-values strands: + width: minw= 8 maxw= 8 nsites: minsites= 2 maxsites= 250 wnsites= 0.8 theta: spmap= uni spfuzz= 0.5 em: prior= dirichlet b= 0.01 maxiter= 50 distance= 1e-05 trim: wg= 11 ws= 1 endgaps= yes data: n= 20000 N= 250 sample: seed= 0 hsfrac= 0 searchsize= 20000 norand= no csites= 1000 Letter frequencies in dataset: A 0.194 C 0.312 G 0.298 T 0.196 Background letter frequencies (from file dataset with add-one prior applied): A 0.194 C 0.312 G 0.298 T 0.196 Background model order: 0 ******************************************************************************** ******************************************************************************** MOTIF TCATGTGA MEME-1 width = 8 sites = 11 llr = 123 E-value = 1.0e-002 ******************************************************************************** -------------------------------------------------------------------------------- Motif TCATGTGA MEME-1 Description -------------------------------------------------------------------------------- Simplified A ::a::::a pos.-specific C :a:::::: probability G :::2a:a: matrix T a::8:a:: bits 2.4 * * * * 2.1 * * * * 1.9 * * * * 1.7 ******** Relative 1.4 ******** Entropy 1.2 ******** (16.2 bits) 0.9 ******** 0.7 ******** 0.5 ******** 0.2 ******** 0.0 -------- Multilevel TCATGTGA consensus sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCATGTGA MEME-1 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr1:45477764-45477844 50 7.85e-06 TGGAGTCCGA TCATGTGA TCTTCAACAT chr17:21427518-21427598 19 7.85e-06 AATCCTCCAG TCATGTGA GGGAGGATGG chr12:114184986-11418506 9 7.85e-06 AGAGCTGG TCATGTGA CCACGGGGTC chr11:6640590-6640670 65 7.85e-06 GGATCTGCTG TCATGTGA CGGATCAC chr1:155211017-155211097 44 7.85e-06 TGTGGATGGG TCATGTGA TGACTAGGAG chr1:155188788-155188868 35 7.85e-06 TGTGGATGGG TCATGTGA TGACTAGGAG chr14:23790112-23790192 68 7.85e-06 GACTGGCTAG TCATGTGA CCTCG chrX:101975569-101975649 54 7.85e-06 TGACGGTGGG TCATGTGA CCAGGCTCTG chr2:20386449-20386529 3 7.85e-06 TA TCATGTGA TCGCTGCGGC chr4:152682081-152682161 73 1.98e-05 AGGGTCTTGG TCAGGTGA chr14:68283253-68283333 53 1.98e-05 TTGAGCCGAG TCAGGTGA CAGAACCCAC -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCATGTGA MEME-1 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr1:45477764-45477844 7.9e-06 49_[+1]_23 chr17:21427518-21427598 7.9e-06 18_[+1]_54 chr12:114184986-11418506 7.9e-06 8_[+1]_64 chr11:6640590-6640670 7.9e-06 64_[+1]_8 chr1:155211017-155211097 7.9e-06 43_[+1]_29 chr1:155188788-155188868 7.9e-06 34_[+1]_38 chr14:23790112-23790192 7.9e-06 67_[+1]_5 chrX:101975569-101975649 7.9e-06 53_[+1]_19 chr2:20386449-20386529 7.9e-06 2_[+1]_70 chr4:152682081-152682161 2e-05 72_[+1] chr14:68283253-68283333 2e-05 52_[+1]_20 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCATGTGA MEME-1 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF TCATGTGA width=8 seqs=11 chr1:45477764-45477844 ( 50) TCATGTGA 1 chr17:21427518-21427598 ( 19) TCATGTGA 1 chr12:114184986-11418506 ( 9) TCATGTGA 1 chr11:6640590-6640670 ( 65) TCATGTGA 1 chr1:155211017-155211097 ( 44) TCATGTGA 1 chr1:155188788-155188868 ( 35) TCATGTGA 1 chr14:23790112-23790192 ( 68) TCATGTGA 1 chrX:101975569-101975649 ( 54) TCATGTGA 1 chr2:20386449-20386529 ( 3) TCATGTGA 1 chr4:152682081-152682161 ( 73) TCAGGTGA 1 chr14:68283253-68283333 ( 53) TCAGGTGA 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCATGTGA MEME-1 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 11.0506 E= 1.0e-002 -1010 -1010 -1010 235 -1010 168 -1010 -1010 236 -1010 -1010 -1010 -1010 -1010 -71 206 -1010 -1010 175 -1010 -1010 -1010 -1010 235 -1010 -1010 175 -1010 236 -1010 -1010 -1010 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCATGTGA MEME-1 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 11 E= 1.0e-002 0.000000 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.181818 0.818182 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCATGTGA MEME-1 regular expression -------------------------------------------------------------------------------- TCATGTGA -------------------------------------------------------------------------------- Time 5.10 secs. ******************************************************************************** ******************************************************************************** MOTIF AAAAAGAA MEME-2 width = 8 sites = 13 llr = 136 E-value = 1.2e-001 ******************************************************************************** -------------------------------------------------------------------------------- Motif AAAAAGAA MEME-2 Description -------------------------------------------------------------------------------- Simplified A a9aa8199 pos.-specific C :1:::2:1 probability G ::::271: matrix T :::::::: bits 2.4 * ** 2.1 * ** 1.9 **** ** 1.7 ***** ** Relative 1.4 ***** ** Entropy 1.2 ***** ** (15.1 bits) 0.9 ***** ** 0.7 ******** 0.5 ******** 0.2 ******** 0.0 -------- Multilevel AAAAAGAA consensus C sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAAAAGAA MEME-2 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr16:57219747-57219827 66 3.08e-06 CTCGCTCTTa aaaaagaa aaaaaaa chr9:97136543-97136623 50 3.08e-06 GATTCTCCGG AAAAAGAA ATCAGTCGTA chr5:139682544-139682624 44 3.08e-06 CTCAGCCTCC AAAAAGAA GACCTCCGCC chr15:75628371-75628451 25 3.08e-06 GCGGGACCGG AAAAAGAA ATTCCCGGGC chr7:6865937-6866017 13 3.08e-06 GCAGGCCCGG AAAAAGAA TCCGCCTCGC chr15:49462086-49462166 7 6.31e-06 TAACTA AAaaacaa acaaacaaac chr15:63413811-63413891 66 6.31e-06 gacagaaagg aaaaacaa ggaagag chr7:99069299-99069379 30 8.32e-06 acacacacac aaaaaaaa ttagccggga chr6:148466267-148466347 59 1.30e-05 GGAATAGAAG AAAAGGAA AAACGAAATA chr16:69556889-69556969 41 2.77e-05 AAGGTCAATT ACAAAGAA GGGGTGTGCA chr19:9649231-9649311 51 2.77e-05 TCTGAAAGGC AAAAAGAC TCTCAGGCGC chr2:61921698-61921778 70 2.77e-05 CCTGTCCCCC AAAAAGGA GGA chr9:86323001-86323081 41 3.27e-05 GTGAAGGACT AAAAGCAA AATGGGGCGG -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAAAAGAA MEME-2 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr16:57219747-57219827 3.1e-06 65_[+2]_7 chr9:97136543-97136623 3.1e-06 49_[+2]_23 chr5:139682544-139682624 3.1e-06 43_[+2]_29 chr15:75628371-75628451 3.1e-06 24_[+2]_48 chr7:6865937-6866017 3.1e-06 12_[+2]_60 chr15:49462086-49462166 6.3e-06 6_[+2]_66 chr15:63413811-63413891 6.3e-06 65_[+2]_7 chr7:99069299-99069379 8.3e-06 29_[+2]_43 chr6:148466267-148466347 1.3e-05 58_[+2]_14 chr16:69556889-69556969 2.8e-05 40_[+2]_32 chr19:9649231-9649311 2.8e-05 50_[+2]_22 chr2:61921698-61921778 2.8e-05 69_[+2]_3 chr9:86323001-86323081 3.3e-05 40_[+2]_32 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAAAAGAA MEME-2 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF AAAAAGAA width=8 seqs=13 chr16:57219747-57219827 ( 66) AAAAAGAA 1 chr9:97136543-97136623 ( 50) AAAAAGAA 1 chr5:139682544-139682624 ( 44) AAAAAGAA 1 chr15:75628371-75628451 ( 25) AAAAAGAA 1 chr7:6865937-6866017 ( 13) AAAAAGAA 1 chr15:49462086-49462166 ( 7) AAAAACAA 1 chr15:63413811-63413891 ( 66) AAAAACAA 1 chr7:99069299-99069379 ( 30) AAAAAAAA 1 chr6:148466267-148466347 ( 59) AAAAGGAA 1 chr16:69556889-69556969 ( 41) ACAAAGAA 1 chr19:9649231-9649311 ( 51) AAAAAGAC 1 chr2:61921698-61921778 ( 70) AAAAAGGA 1 chr9:86323001-86323081 ( 41) AAAAGCAA 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAAAAGAA MEME-2 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 12.0849 E= 1.2e-001 236 -1035 -1035 -1035 225 -202 -1035 -1035 236 -1035 -1035 -1035 236 -1035 -1035 -1035 212 -1035 -95 -1035 -134 -44 122 -1035 225 -1035 -195 -1035 225 -202 -1035 -1035 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAAAAGAA MEME-2 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 13 E= 1.2e-001 1.000000 0.000000 0.000000 0.000000 0.923077 0.076923 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.846154 0.000000 0.153846 0.000000 0.076923 0.230769 0.692308 0.000000 0.923077 0.000000 0.076923 0.000000 0.923077 0.076923 0.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAAAAGAA MEME-2 regular expression -------------------------------------------------------------------------------- AAAAA[GC]AA -------------------------------------------------------------------------------- Time 8.97 secs. ******************************************************************************** ******************************************************************************** MOTIF GCMGGAAG MEME-3 width = 8 sites = 32 llr = 267 E-value = 1.5e+001 ******************************************************************************** -------------------------------------------------------------------------------- Motif GCMGGAAG MEME-3 Description -------------------------------------------------------------------------------- Simplified A 2351:aa: pos.-specific C 185::::: probability G 7::9a::a matrix T :::::::: bits 2.4 ** 2.1 ** 1.9 ** 1.7 **** Relative 1.4 **** Entropy 1.2 ***** (12.0 bits) 0.9 ******* 0.7 ******** 0.5 ******** 0.2 ******** 0.0 -------- Multilevel GCAGGAAG consensus AC sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GCMGGAAG MEME-3 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr20:61408503-61408583 69 1.80e-05 aggagatgag gcaggaag gagg chr2:113931365-113931445 68 1.80e-05 TATCTTGTGG GCAGGAAG TGTGA chr19:8617796-8617876 71 1.80e-05 GGGACCATGA GCAGGAAG TG chr12:131239198-13123927 6 1.80e-05 aagga gcaggaag taaagcagga chr20:2644835-2644915 7 1.80e-05 TTTCCC GCAGGAAG TCGCGTGGGA chr4:37003435-37003515 3 1.80e-05 aa gcaggaag agagccagca chr16:71496087-71496167 53 4.69e-05 CCCCGGCGCT GCCGGAAG TGCGTCACCA chr12:42719932-42720012 24 4.69e-05 CATTGCGCGC GCCGGAAG TACCTACCTG chr15:74988326-74988406 23 4.69e-05 CGCCGCCGCT GCCGGAAG CGCCCCCACG chr9:125675519-125675599 58 4.69e-05 GTCTGCCCAA GCCGGAAG ATGGACTTAG chr12:39932573-39932653 37 4.69e-05 acctaccctg gccggaag acagctaccc chr19:56092329-56092409 21 4.69e-05 TGGCTGGGAA GCCGGAAG CGGGAGGACG chr17:73258044-73258124 60 5.80e-05 GCGCTGCGAG GAAGGAAG GGGGCCACAG chr16:16177770-16177850 2 5.80e-05 a gaaggaag tacattctac chr19:51728323-51728403 21 6.97e-05 TTCTGCTCAC ACAGGAAG CCCTGGAAGC chr6:28220010-28220090 43 6.97e-05 AGGCTGGGGC ACAGGAAG TCTCGATGGG chr1:155211017-155211097 73 6.97e-05 GTCACATGAC ACAGGAAG chr1:155188788-155188868 64 6.97e-05 GTCACATGAC ACAGGAAG TGAGGCAAT chr13:103498046-10349812 1 8.77e-05 . GACGGAAG CAAGTAACCA chr15:65426182-65426262 1 8.77e-05 . GACGGAAG TGACGTCGTT chr1:156265390-156265470 64 8.77e-05 CAATTCAGCC GACGGAAG AGGTGCCAG chr1:7887471-7887551 2 1.06e-04 C ACCGGAAG GCCTGCATGG chr17:56709487-56709567 58 1.25e-04 ATGATCGGAA GCAAGAAG GCCCTTCGAG chr16:1020816-1020896 14 1.75e-04 ATCCGGGTCA GCCAGAAG GTGCCCGTGT chr13:53191601-53191681 12 1.75e-04 CCAGACCAGA AACGGAAG AGAGCGCGGG chr5:132362047-132362127 18 1.75e-04 CCCCCCGGGA GCCAGAAG AGTGTTTGAG chr17:7218745-7218825 15 1.82e-04 CCTCACAGGT GAAAGAAG GCGGAAGCGC chr19:10426575-10426655 2 2.12e-04 A CCCGGAAG TGCCCCCAGG chr22:26908381-26908461 50 2.12e-04 TACACCAGAA CCCGGAAG CACCGTGGCC chr13:114103560-11410364 50 2.12e-04 GAGAGACACA CCCGGAAG GAGTGAGCCC chr20:18447979-18448059 29 2.32e-04 CGCCGAAAGG CAAGGAAG GACCGGCTGC chr17:73663263-73663343 56 2.91e-04 GGAGCCAGGC GCAGGAAA CTGCCGTTTT -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GCMGGAAG MEME-3 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr20:61408503-61408583 1.8e-05 68_[+3]_4 chr2:113931365-113931445 1.8e-05 67_[+3]_5 chr19:8617796-8617876 1.8e-05 70_[+3]_2 chr12:131239198-13123927 1.8e-05 5_[+3]_67 chr20:2644835-2644915 1.8e-05 6_[+3]_66 chr4:37003435-37003515 1.8e-05 2_[+3]_70 chr16:71496087-71496167 4.7e-05 52_[+3]_20 chr12:42719932-42720012 4.7e-05 23_[+3]_49 chr15:74988326-74988406 4.7e-05 22_[+3]_50 chr9:125675519-125675599 4.7e-05 57_[+3]_15 chr12:39932573-39932653 4.7e-05 36_[+3]_36 chr19:56092329-56092409 4.7e-05 20_[+3]_52 chr17:73258044-73258124 5.8e-05 59_[+3]_13 chr16:16177770-16177850 5.8e-05 1_[+3]_71 chr19:51728323-51728403 7e-05 20_[+3]_52 chr6:28220010-28220090 7e-05 42_[+3]_30 chr1:155211017-155211097 7e-05 72_[+3] chr1:155188788-155188868 7e-05 63_[+3]_9 chr13:103498046-10349812 8.8e-05 [+3]_72 chr15:65426182-65426262 8.8e-05 [+3]_72 chr1:156265390-156265470 8.8e-05 63_[+3]_9 chr1:7887471-7887551 0.00011 1_[+3]_71 chr17:56709487-56709567 0.00013 57_[+3]_15 chr16:1020816-1020896 0.00017 13_[+3]_59 chr13:53191601-53191681 0.00017 11_[+3]_61 chr5:132362047-132362127 0.00017 17_[+3]_55 chr17:7218745-7218825 0.00018 14_[+3]_58 chr19:10426575-10426655 0.00021 1_[+3]_71 chr22:26908381-26908461 0.00021 49_[+3]_23 chr13:114103560-11410364 0.00021 49_[+3]_23 chr20:18447979-18448059 0.00023 28_[+3]_44 chr17:73663263-73663343 0.00029 55_[+3]_17 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GCMGGAAG MEME-3 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF GCMGGAAG width=8 seqs=32 chr20:61408503-61408583 ( 69) GCAGGAAG 1 chr2:113931365-113931445 ( 68) GCAGGAAG 1 chr19:8617796-8617876 ( 71) GCAGGAAG 1 chr12:131239198-13123927 ( 6) GCAGGAAG 1 chr20:2644835-2644915 ( 7) GCAGGAAG 1 chr4:37003435-37003515 ( 3) GCAGGAAG 1 chr16:71496087-71496167 ( 53) GCCGGAAG 1 chr12:42719932-42720012 ( 24) GCCGGAAG 1 chr15:74988326-74988406 ( 23) GCCGGAAG 1 chr9:125675519-125675599 ( 58) GCCGGAAG 1 chr12:39932573-39932653 ( 37) GCCGGAAG 1 chr19:56092329-56092409 ( 21) GCCGGAAG 1 chr17:73258044-73258124 ( 60) GAAGGAAG 1 chr16:16177770-16177850 ( 2) GAAGGAAG 1 chr19:51728323-51728403 ( 21) ACAGGAAG 1 chr6:28220010-28220090 ( 43) ACAGGAAG 1 chr1:155211017-155211097 ( 73) ACAGGAAG 1 chr1:155188788-155188868 ( 64) ACAGGAAG 1 chr13:103498046-10349812 ( 1) GACGGAAG 1 chr15:65426182-65426262 ( 1) GACGGAAG 1 chr1:156265390-156265470 ( 64) GACGGAAG 1 chr1:7887471-7887551 ( 2) ACCGGAAG 1 chr17:56709487-56709567 ( 58) GCAAGAAG 1 chr16:1020816-1020896 ( 14) GCCAGAAG 1 chr13:53191601-53191681 ( 12) AACGGAAG 1 chr5:132362047-132362127 ( 18) GCCAGAAG 1 chr17:7218745-7218825 ( 15) GAAAGAAG 1 chr19:10426575-10426655 ( 2) CCCGGAAG 1 chr22:26908381-26908461 ( 50) CCCGGAAG 1 chr13:114103560-11410364 ( 50) CCCGGAAG 1 chr20:18447979-18448059 ( 29) CAAGGAAG 1 chr17:73663263-73663343 ( 56) GCAGGAAA 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GCMGGAAG MEME-3 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 9.89106 E= 1.5e+001 -5 -132 121 -1164 36 126 -1164 -1164 136 68 -1164 -1164 -64 -1164 156 -1164 -1164 -1164 175 -1164 236 -1164 -1164 -1164 236 -1164 -1164 -1164 -263 -1164 170 -1164 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GCMGGAAG MEME-3 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 32 E= 1.5e+001 0.187500 0.125000 0.687500 0.000000 0.250000 0.750000 0.000000 0.000000 0.500000 0.500000 0.000000 0.000000 0.125000 0.000000 0.875000 0.000000 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.031250 0.000000 0.968750 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GCMGGAAG MEME-3 regular expression -------------------------------------------------------------------------------- G[CA][AC]GGAAG -------------------------------------------------------------------------------- Time 12.80 secs. ******************************************************************************** ******************************************************************************** MOTIF TTTTTDKT MEME-4 width = 8 sites = 17 llr = 160 E-value = 2.1e+002 ******************************************************************************** -------------------------------------------------------------------------------- Motif TTTTTDKT MEME-4 Description -------------------------------------------------------------------------------- Simplified A :::::311 pos.-specific C ::3::::: probability G ::::143: matrix T aa7a9469 bits 2.4 ** * 2.1 ** * * 1.9 ** * * 1.7 ** ** * Relative 1.4 ** ** * Entropy 1.2 ***** * (13.5 bits) 0.9 ***** ** 0.7 ***** ** 0.5 ******** 0.2 ******** 0.0 -------- Multilevel TTTTTGTT consensus C TG sequence A -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTTTTDKT MEME-4 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr2:108364809-108364889 28 2.18e-06 gccaggctga tttttttt gtattttgta chr13:49684334-49684414 8 2.18e-06 CGTTTGC TTTTTTTT CCCCCTTGCC chr1:154600493-154600573 52 7.65e-06 GAAATTAAGG TTTTTGTT GCTACGTCTT chr22:19615313-19615393 64 1.10e-05 gcctggctaa ttttttgt atttttagt chr9:140100171-140100251 23 1.42e-05 TGCCTTCTAG TTTTTAGT CTCAGACCAG chr6:116574637-116574717 68 1.42e-05 GATGGCGCGT TTTTTAGT CGTCA chr13:45563676-45563756 48 1.77e-05 GATCGCGGGA TTCTTTTT GGATAGGGTT chr9:99776071-99776151 21 1.77e-05 TACGACTAAT TTCTTTTT CCGGAGAATC chr15:74392520-74392600 57 1.77e-05 GCCCGGGAAT TTCTTTTT CCGGTCCCGC chr14:32030638-32030718 33 2.83e-05 CGTCTGCTGC TTTTTGGT GGGGTGTCGC chr5:137548849-137548929 52 3.05e-05 CAGCAGTTGC TTTTTAAT TTCCCGCAAA chr1:241987387-241987467 55 3.05e-05 TGAGAGACAT TTTTTAAT GCTACACACC chr6:71122828-71122908 11 3.57e-05 TTTTGCCCTC TTCTTGTT CACTACTCTT chr17:73663263-73663343 70 5.61e-05 GAAACTGCCG TTTTGATT GGT chr20:16710646-16710726 30 7.69e-05 CGTTTCCTGC TTTTGGTT CTTACAGTAG chr3:119396033-119396113 33 7.69e-05 ATCGCGCGCC TTCTTGGT CTCCGGGCAA chr10:15902615-15902695 55 8.35e-05 GGGGTGGTAG TTTTTGTA TTGGGAAGGG -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTTTTDKT MEME-4 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr2:108364809-108364889 2.2e-06 27_[+4]_45 chr13:49684334-49684414 2.2e-06 7_[+4]_65 chr1:154600493-154600573 7.6e-06 51_[+4]_21 chr22:19615313-19615393 1.1e-05 63_[+4]_9 chr9:140100171-140100251 1.4e-05 22_[+4]_50 chr6:116574637-116574717 1.4e-05 67_[+4]_5 chr13:45563676-45563756 1.8e-05 47_[+4]_25 chr9:99776071-99776151 1.8e-05 20_[+4]_52 chr15:74392520-74392600 1.8e-05 56_[+4]_16 chr14:32030638-32030718 2.8e-05 32_[+4]_40 chr5:137548849-137548929 3e-05 51_[+4]_21 chr1:241987387-241987467 3e-05 54_[+4]_18 chr6:71122828-71122908 3.6e-05 10_[+4]_62 chr17:73663263-73663343 5.6e-05 69_[+4]_3 chr20:16710646-16710726 7.7e-05 29_[+4]_43 chr3:119396033-119396113 7.7e-05 32_[+4]_40 chr10:15902615-15902695 8.4e-05 54_[+4]_18 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTTTTDKT MEME-4 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF TTTTTDKT width=8 seqs=17 chr2:108364809-108364889 ( 28) TTTTTTTT 1 chr13:49684334-49684414 ( 8) TTTTTTTT 1 chr1:154600493-154600573 ( 52) TTTTTGTT 1 chr22:19615313-19615393 ( 64) TTTTTTGT 1 chr9:140100171-140100251 ( 23) TTTTTAGT 1 chr6:116574637-116574717 ( 68) TTTTTAGT 1 chr13:45563676-45563756 ( 48) TTCTTTTT 1 chr9:99776071-99776151 ( 21) TTCTTTTT 1 chr15:74392520-74392600 ( 57) TTCTTTTT 1 chr14:32030638-32030718 ( 33) TTTTTGGT 1 chr5:137548849-137548929 ( 52) TTTTTAAT 1 chr1:241987387-241987467 ( 55) TTTTTAAT 1 chr6:71122828-71122908 ( 11) TTCTTGTT 1 chr17:73663263-73663343 ( 70) TTTTGATT 1 chr20:16710646-16710726 ( 30) TTTTGGTT 1 chr3:119396033-119396113 ( 33) TTCTTGGT 1 chr10:15902615-15902695 ( 55) TTTTTGTA 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTTTTDKT MEME-4 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 11.4326 E= 2.1e+002 -1073 -1073 -1073 235 -1073 -1073 -1073 235 -1073 -9 -1073 185 -1073 -1073 -1073 235 -1073 -1073 -134 217 60 -1073 25 85 -72 -1073 -2 159 -172 -1073 -1073 227 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTTTTDKT MEME-4 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 17 E= 2.1e+002 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.294118 0.000000 0.705882 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.117647 0.882353 0.294118 0.000000 0.352941 0.352941 0.117647 0.000000 0.294118 0.588235 0.058824 0.000000 0.000000 0.941176 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTTTTDKT MEME-4 regular expression -------------------------------------------------------------------------------- TT[TC]TT[GTA][TG]T -------------------------------------------------------------------------------- Time 16.57 secs. ******************************************************************************** ******************************************************************************** MOTIF CACACACA MEME-5 width = 8 sites = 17 llr = 157 E-value = 1.5e+003 ******************************************************************************** -------------------------------------------------------------------------------- Motif CACACACA MEME-5 Description -------------------------------------------------------------------------------- Simplified A :a19:8:a pos.-specific C 9:9191a: probability G ::::1::: matrix T 1:::11:: bits 2.4 * * 2.1 * * 1.9 * * 1.7 * * ** Relative 1.4 *** *** Entropy 1.2 ******** (13.4 bits) 0.9 ******** 0.7 ******** 0.5 ******** 0.2 ******** 0.0 -------- Multilevel CACACACA consensus sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CACACACA MEME-5 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr3:194048462-194048542 57 1.34e-05 caccacacac cacacaca accacacacc chr3:194047454-194047534 69 1.34e-05 tcacacatac cacacaca ccac chr7:99069299-99069379 21 1.34e-05 ctactaaaaa cacacaca caaaaaaaat chr4:6727669-6727749 61 1.34e-05 gcacacacat cacacaca gtcataccac chr4:6727464-6727544 54 1.34e-05 tcacacacat cacacaca atcatacgac chr14:102149882-10214996 58 1.34e-05 tacacacatg cacacaca tacacacaca chr22:45128729-45128809 28 1.34e-05 ctacacactg cacacaca caccacacac chr17:77801103-77801183 44 1.34e-05 cacacacacg cacacaca tgcacacatg chr6:148466267-148466347 6 2.19e-05 TTTTA TACACACA AGCACATTGA chr11:130786211-13078629 23 3.54e-05 ACCGCGCGCC CACACTCA GCCCCGACCT chr10:75910441-75910521 63 3.54e-05 TCCCGCCCCT CACACTCA CCCCAACACC chr7:30155363-30155443 44 4.38e-05 TACATACGTG CACATACA TGTATACACG chr13:52768537-52768617 29 5.22e-05 GTCCCCATGC CAAACACA TCCCCCGCGC chr12:66524430-66524510 67 7.38e-05 GAGAAACGAA CACCCACA CCTCAC chr14:71067290-71067370 3 8.66e-05 TC CACAGACA ATCAAGAGAC chr1:241987387-241987467 67 1.08e-04 TTTAATGCTA CACACCCA GTGTCA chr1:143467499-143467579 69 1.41e-04 CCCTCGCACC TACCCACA GGGA -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CACACACA MEME-5 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr3:194048462-194048542 1.3e-05 56_[+5]_16 chr3:194047454-194047534 1.3e-05 68_[+5]_4 chr7:99069299-99069379 1.3e-05 20_[+5]_52 chr4:6727669-6727749 1.3e-05 60_[+5]_12 chr4:6727464-6727544 1.3e-05 53_[+5]_19 chr14:102149882-10214996 1.3e-05 57_[+5]_15 chr22:45128729-45128809 1.3e-05 27_[+5]_45 chr17:77801103-77801183 1.3e-05 43_[+5]_29 chr6:148466267-148466347 2.2e-05 5_[+5]_67 chr11:130786211-13078629 3.5e-05 22_[+5]_50 chr10:75910441-75910521 3.5e-05 62_[+5]_10 chr7:30155363-30155443 4.4e-05 43_[+5]_29 chr13:52768537-52768617 5.2e-05 28_[+5]_44 chr12:66524430-66524510 7.4e-05 66_[+5]_6 chr14:71067290-71067370 8.7e-05 2_[+5]_70 chr1:241987387-241987467 0.00011 66_[+5]_6 chr1:143467499-143467579 0.00014 68_[+5]_4 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CACACACA MEME-5 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF CACACACA width=8 seqs=17 chr3:194048462-194048542 ( 57) CACACACA 1 chr3:194047454-194047534 ( 69) CACACACA 1 chr7:99069299-99069379 ( 21) CACACACA 1 chr4:6727669-6727749 ( 61) CACACACA 1 chr4:6727464-6727544 ( 54) CACACACA 1 chr14:102149882-10214996 ( 58) CACACACA 1 chr22:45128729-45128809 ( 28) CACACACA 1 chr17:77801103-77801183 ( 44) CACACACA 1 chr6:148466267-148466347 ( 6) TACACACA 1 chr11:130786211-13078629 ( 23) CACACTCA 1 chr10:75910441-75910521 ( 63) CACACTCA 1 chr7:30155363-30155443 ( 44) CACATACA 1 chr13:52768537-52768617 ( 29) CAAACACA 1 chr12:66524430-66524510 ( 67) CACCCACA 1 chr14:71067290-71067370 ( 3) CACAGACA 1 chr1:241987387-241987467 ( 67) CACACCCA 1 chr1:143467499-143467579 ( 69) TACCCACA 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CACACACA MEME-5 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 10.8621 E= 1.5e+003 -1073 150 -1073 -73 236 -1073 -1073 -1073 -172 159 -1073 -1073 218 -141 -1073 -1073 -1073 150 -234 -173 208 -241 -1073 -73 -1073 168 -1073 -1073 236 -1073 -1073 -1073 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CACACACA MEME-5 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 17 E= 1.5e+003 0.000000 0.882353 0.000000 0.117647 1.000000 0.000000 0.000000 0.000000 0.058824 0.941176 0.000000 0.000000 0.882353 0.117647 0.000000 0.000000 0.000000 0.882353 0.058824 0.058824 0.823529 0.058824 0.000000 0.117647 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CACACACA MEME-5 regular expression -------------------------------------------------------------------------------- CACACACA -------------------------------------------------------------------------------- Time 20.30 secs. ******************************************************************************** ******************************************************************************** SUMMARY OF MOTIFS ******************************************************************************** -------------------------------------------------------------------------------- Combined block diagrams: non-overlapping sites with p-value < 0.0001 -------------------------------------------------------------------------------- SEQUENCE NAME COMBINED P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr17:77801103-77801183 6.22e-02 5_[+5(1.34e-05)]_6_[+5(1.34e-05)]_6_\ [+5(1.34e-05)]_2_[+5(1.34e-05)]_29 chr1:155179085-155179165 9.08e-01 80 chr17:36453168-36453248 4.78e-01 80 chr15:74392520-74392600 1.34e-02 56_[+4(1.77e-05)]_16 chr9:131133705-131133785 9.48e-01 80 chr14:23938966-23939046 3.62e-01 80 chr1:42922457-42922537 3.63e-01 80 chr9:33076567-33076647 8.51e-01 80 chr2:20386449-20386529 3.46e-03 2_[+1(7.85e-06)]_70 chr17:45569699-45569779 9.44e-01 80 chr14:68283253-68283333 8.03e-03 52_[+1(1.98e-05)]_20 chr22:45128729-45128809 6.46e-02 27_[+5(1.34e-05)]_45 chr2:128051580-128051660 7.26e-01 80 chr20:8012319-8012399 9.91e-01 80 chr20:18447979-18448059 6.83e-02 80 chr2:32502980-32503060 3.82e-02 80 chr3:127279266-127279346 8.44e-01 80 chr1:156265390-156265470 3.56e-02 63_[+3(8.77e-05)]_9 chrX:101975569-101975649 4.02e-02 53_[+1(7.85e-06)]_19 chrX:102809792-102809872 1.81e-01 80 chr7:2598540-2598620 9.94e-01 80 chr11:66774066-66774146 1.08e-01 80 chr3:127279466-127279546 7.94e-01 80 chr7:6865937-6866017 1.14e-03 12_[+2(3.08e-06)]_60 chr17:42767030-42767110 9.06e-01 80 chr19:56092329-56092409 2.25e-01 20_[+3(4.69e-05)]_52 chr14:23790112-23790192 4.32e-02 67_[+1(7.85e-06)]_5 chr14:102149882-10214996 7.69e-02 9_[+5(1.34e-05)]_4_[+5(1.34e-05)]_\ 10_[+5(1.34e-05)]_[+5(2.19e-05)]_2_[+5(1.34e-05)]_2_[+5(1.34e-05)]_5 chr16:14014133-14014213 9.88e-01 80 chr10:102027360-10202744 1.43e-01 80 chr2:61921698-61921778 3.34e-02 69_[+2(2.77e-05)]_3 chr7:112580374-112580454 1.28e-01 80 chr12:53541142-53541222 1.05e-01 80 chr12:53645953-53646033 7.01e-01 80 chr8:30013906-30013986 3.06e-01 80 chr1:155188788-155188868 2.49e-04 34_[+1(7.85e-06)]_21_[+3(6.97e-05)]_\ 9 chr17:7218745-7218825 2.13e-02 80 chr17:42422381-42422461 1.44e-01 80 chr1:151735902-151735982 5.57e-01 80 chr3:195426117-195426197 8.21e-01 80 chr5:1345357-1345437 1.00e+00 80 chrX:48659877-48659957 3.28e-01 80 chr14:71067290-71067370 1.18e-02 2_[+5(8.66e-05)]_70 chr3:66271487-66271567 9.96e-01 80 chr16:5083856-5083936 7.26e-01 80 chr1:155211017-155211097 8.36e-04 43_[+1(7.85e-06)]_21_[+3(6.97e-05)] chr16:16177770-16177850 4.96e-04 1_[+3(5.80e-05)]_71 chrX:102024111-102024191 4.41e-01 80 chr15:42500355-42500435 9.74e-01 80 chr7:30155363-30155443 2.04e-01 5_[+5(4.38e-05)]_30_[+5(4.38e-05)]_\ 29 chr2:68290051-68290131 7.45e-02 80 chr17:40976189-40976269 1.00e+00 80 chr12:39932573-39932653 4.80e-02 36_[+3(4.69e-05)]_36 chr16:69796070-69796150 3.85e-03 80 chr19:18747917-18747997 2.83e-01 80 chr14:75179829-75179909 2.87e-01 80 chr22:19615313-19615393 7.71e-02 63_[+4(1.10e-05)]_1_[+4(1.42e-05)] chr10:51827657-51827737 9.95e-01 80 chr11:6640590-6640670 8.59e-02 64_[+1(7.85e-06)]_8 chr9:99776071-99776151 2.18e-02 20_[+4(1.77e-05)]_52 chr19:9649231-9649311 8.54e-03 50_[+2(2.77e-05)]_22 chr1:7887471-7887551 2.19e-01 80 chr13:114103560-11410364 1.22e-01 80 chr3:75834523-75834603 9.40e-01 80 chr9:125675519-125675599 5.51e-02 57_[+3(4.69e-05)]_15 chr14:55878453-55878533 8.84e-01 80 chr4:37003435-37003515 1.65e-02 2_[+3(1.80e-05)]_27_[+3(1.80e-05)]_\ 35 chr17:56709487-56709567 5.25e-02 80 chr11:94227238-94227318 7.87e-01 80 chr22:26908381-26908461 1.87e-01 80 chr1:241987387-241987467 2.11e-03 54_[+4(3.05e-05)]_18 chr16:69556889-69556969 3.15e-04 40_[+2(2.77e-05)]_32 chr4:148538592-148538672 2.90e-01 80 chr12:114184986-11418506 3.15e-02 8_[+1(7.85e-06)]_64 chr13:49684334-49684414 5.02e-04 7_[+4(2.18e-06)]_30_[+1(9.44e-05)]_\ 6_[+1(9.44e-05)]_13 chr1:7831373-7831453 7.06e-01 80 chr10:26986390-26986470 9.56e-01 80 chr8:48173254-48173334 6.85e-01 80 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