******************************************************************************** MEME - Motif discovery tool ******************************************************************************** MEME version 5.3.3 (Release date: Sun Feb 7 15:39:52 2021 -0800) For further information on how to interpret these results please access https://meme-suite.org/meme. To get a copy of the MEME Suite software please access https://meme-suite.org. ******************************************************************************** ******************************************************************************** REFERENCE ******************************************************************************** If you use this program in your research, please cite: Timothy L. Bailey and Charles Elkan, "Fitting a mixture model by expectation maximization to discover motifs in biopolymers", Proceedings of the Second International Conference on Intelligent Systems for Molecular Biology, pp. 28-36, AAAI Press, Menlo Park, California, 1994. ******************************************************************************** ******************************************************************************** TRAINING SET ******************************************************************************** PRIMARY SEQUENCES= ../result/final_prediction/K562/fasta/RankLinear0.6_40/PCBP1.fasta CONTROL SEQUENCES= --none-- ALPHABET= ACGT Sequence name Weight Length Sequence name Weight Length ------------- ------ ------ ------------- ------ ------ chr21:47580943-47581023 1.0000 80 chr16:88857800-88857880 1.0000 80 chr8:22456439-22456519 1.0000 80 chr8:142085752-142085832 1.0000 80 chr4:726015-726095 1.0000 80 chrX:153665440-153665520 1.0000 80 chr15:90545207-90545287 1.0000 80 chr5:180527779-180527859 1.0000 80 chr17:75352636-75352716 1.0000 80 chr10:89623291-89623371 1.0000 80 chr10:70262768-70262848 1.0000 80 chr1:182992134-182992214 1.0000 80 chr8:98748669-98748749 1.0000 80 chr10:35104320-35104400 1.0000 80 chr2:3738086-3738166 1.0000 80 chr4:1769012-1769092 1.0000 80 chr1:1052359-1052439 1.0000 80 chr7:1546072-1546152 1.0000 80 chr7:130895530-130895610 1.0000 80 chr2:170595244-170595324 1.0000 80 chr9:140306231-140306311 1.0000 80 chr20:29647715-29647795 1.0000 80 chr8:144635221-144635301 1.0000 80 chr13:50571159-50571239 1.0000 80 chr2:26699270-26699350 1.0000 80 chr1:1363630-1363710 1.0000 80 chr7:128046207-128046287 1.0000 80 chr5:130614326-130614406 1.0000 80 chr17:44202476-44202556 1.0000 80 chr2:3737792-3737872 1.0000 80 chr5:176559876-176559956 1.0000 80 chr1:32083861-32083941 1.0000 80 chr11:34006997-34007077 1.0000 80 chr9:140410082-140410162 1.0000 80 chr9:37286676-37286756 1.0000 80 chr1:25056852-25056932 1.0000 80 chr6:159364585-159364665 1.0000 80 chr1:232861190-232861270 1.0000 80 chr16:23993262-23993342 1.0000 80 chr7:550427-550507 1.0000 80 chr6:24238433-24238513 1.0000 80 chr12:114450688-11445076 1.0000 80 chr17:7155029-7155109 1.0000 80 chr1:235575337-235575417 1.0000 80 chr5:96272069-96272149 1.0000 80 chr1:32273032-32273112 1.0000 80 chr4:94369979-94370059 1.0000 80 chr9:139591195-139591275 1.0000 80 chr21:38411957-38412037 1.0000 80 chr19:35759842-35759922 1.0000 80 chr1:241838429-241838509 1.0000 80 chr1:27320085-27320165 1.0000 80 chr4:175145847-175145927 1.0000 80 chr22:19746138-19746218 1.0000 80 chr1:1179981-1180061 1.0000 80 chr16:447754-447834 1.0000 80 chr5:1667318-1667398 1.0000 80 chr5:108676228-108676308 1.0000 80 chr9:132372533-132372613 1.0000 80 chr15:102033471-10203355 1.0000 80 chr19:39005868-39005948 1.0000 80 chr6:34941753-34941833 1.0000 80 chr1:156716935-156717015 1.0000 80 chr14:102227447-10222752 1.0000 80 chr7:151574771-151574851 1.0000 80 chr11:4637239-4637319 1.0000 80 chr1:27929568-27929648 1.0000 80 chr19:1827053-1827133 1.0000 80 chr1:221873484-221873564 1.0000 80 chr4:1750626-1750706 1.0000 80 chr8:74790690-74790770 1.0000 80 chr7:152190728-152190808 1.0000 80 chr17:28257197-28257277 1.0000 80 chr19:1123159-1123239 1.0000 80 chr5:34698048-34698128 1.0000 80 chr2:174877694-174877774 1.0000 80 chr22:21311813-21311893 1.0000 80 chr13:23500586-23500666 1.0000 80 chr7:150342888-150342968 1.0000 80 chr7:6543340-6543420 1.0000 80 chr1:28586543-28586623 1.0000 80 chr6:33378572-33378652 1.0000 80 chr7:128341517-128341597 1.0000 80 chr10:32144088-32144168 1.0000 80 chr17:5185440-5185520 1.0000 80 chr19:3367328-3367408 1.0000 80 chr8:68252035-68252115 1.0000 80 chr1:12655578-12655658 1.0000 80 chr9:95821064-95821144 1.0000 80 chr20:33292011-33292091 1.0000 80 chr17:80606749-80606829 1.0000 80 chr10:80826892-80826972 1.0000 80 chr15:38544419-38544499 1.0000 80 chr15:79603361-79603441 1.0000 80 chr19:1161950-1162030 1.0000 80 chr2:61698182-61698262 1.0000 80 chr5:68264382-68264462 1.0000 80 chr6:44095185-44095265 1.0000 80 chr5:176924076-176924156 1.0000 80 chr9:139943096-139943176 1.0000 80 chr5:171881142-171881222 1.0000 80 chr1:87794614-87794694 1.0000 80 chr1:160370211-160370291 1.0000 80 chr5:42978705-42978785 1.0000 80 chr16:78638472-78638552 1.0000 80 chr19:3046839-3046919 1.0000 80 chr17:46089707-46089787 1.0000 80 chr8:28259957-28260037 1.0000 80 chr6:50603335-50603415 1.0000 80 chr12:48744834-48744914 1.0000 80 chr1:42687793-42687873 1.0000 80 chr8:130491160-130491240 1.0000 80 chr12:57916707-57916787 1.0000 80 chr12:121268392-12126847 1.0000 80 chr3:185083562-185083642 1.0000 80 chr8:142425896-142425976 1.0000 80 chr7:128341273-128341353 1.0000 80 chr6:79787980-79788060 1.0000 80 chr22:20767577-20767657 1.0000 80 chr9:132359507-132359587 1.0000 80 chr17:56408770-56408850 1.0000 80 chr12:132579249-13257932 1.0000 80 chr16:89313546-89313626 1.0000 80 chr21:47843802-47843882 1.0000 80 chr9:136223449-136223529 1.0000 80 chr15:75940067-75940147 1.0000 80 chr11:2913886-2913966 1.0000 80 chr13:50570882-50570962 1.0000 80 chr1:90098716-90098796 1.0000 80 chr1:204463858-204463938 1.0000 80 chr2:174829109-174829189 1.0000 80 chr19:55646213-55646293 1.0000 80 chr19:798174-798254 1.0000 80 chr5:34698255-34698335 1.0000 80 chr10:73958149-73958229 1.0000 80 chr19:42637388-42637468 1.0000 80 chr18:74534792-74534872 1.0000 80 chr6:44214187-44214267 1.0000 80 chr17:78564878-78564958 1.0000 80 chr6:20402514-20402594 1.0000 80 chr7:158424609-158424689 1.0000 80 chr10:63491548-63491628 1.0000 80 chr10:81204733-81204813 1.0000 80 chr1:2332594-2332674 1.0000 80 chr7:26241556-26241636 1.0000 80 chr6:165038109-165038189 1.0000 80 chr16:8962331-8962411 1.0000 80 chr18:45456851-45456931 1.0000 80 chr19:40669135-40669215 1.0000 80 chr20:62104414-62104494 1.0000 80 chr19:955141-955221 1.0000 80 chr18:29616631-29616711 1.0000 80 chr2:172017000-172017080 1.0000 80 chr17:20945898-20945978 1.0000 80 chr7:77396247-77396327 1.0000 80 chr2:230786721-230786801 1.0000 80 chr4:174089929-174090009 1.0000 80 chr8:143858776-143858856 1.0000 80 chr6:44010163-44010243 1.0000 80 chr19:3577007-3577087 1.0000 80 chr9:136223681-136223761 1.0000 80 chr5:137803113-137803193 1.0000 80 chr10:23384502-23384582 1.0000 80 chr1:9600007-9600087 1.0000 80 chr8:19675154-19675234 1.0000 80 chr1:895958-896038 1.0000 80 chr5:15411132-15411212 1.0000 80 chr5:44779421-44779501 1.0000 80 chr6:151712009-151712089 1.0000 80 chr1:21713382-21713462 1.0000 80 chr11:77489345-77489425 1.0000 80 chr6:166815843-166815923 1.0000 80 chr4:94370181-94370261 1.0000 80 chr19:42784897-42784977 1.0000 80 chr11:65192506-65192586 1.0000 80 chr17:73775382-73775462 1.0000 80 chr10:70092089-70092169 1.0000 80 chr11:65601036-65601116 1.0000 80 chr22:20786080-20786160 1.0000 80 chr1:153895165-153895245 1.0000 80 chr6:155054899-155054979 1.0000 80 chr7:128864874-128864954 1.0000 80 chr2:163605220-163605300 1.0000 80 chr1:16494444-16494524 1.0000 80 chr19:13265766-13265846 1.0000 80 chr16:46612217-46612297 1.0000 80 chr11:77185060-77185140 1.0000 80 chr2:55711202-55711282 1.0000 80 chr10:65389964-65390044 1.0000 80 chr5:44888712-44888792 1.0000 80 chr1:6453759-6453839 1.0000 80 chr7:138087653-138087733 1.0000 80 chr3:130355483-130355563 1.0000 80 chr8:79100825-79100905 1.0000 80 chr1:167599521-167599601 1.0000 80 chr4:151579571-151579651 1.0000 80 chr14:77413749-77413829 1.0000 80 chr7:23510784-23510864 1.0000 80 chr1:203765039-203765119 1.0000 80 chr1:180992052-180992132 1.0000 80 chr22:20226790-20226870 1.0000 80 chr1:2477805-2477885 1.0000 80 chr3:20081530-20081610 1.0000 80 chr7:75831069-75831149 1.0000 80 chr12:46384141-46384221 1.0000 80 chr12:50987399-50987479 1.0000 80 chr10:43892359-43892439 1.0000 80 chrX:122994040-122994120 1.0000 80 chr3:38495246-38495326 1.0000 80 chr8:4032310-4032390 1.0000 80 chr10:13142153-13142233 1.0000 80 chr1:3816796-3816876 1.0000 80 chr22:38901870-38901950 1.0000 80 chr16:22385330-22385410 1.0000 80 chr15:72523637-72523717 1.0000 80 chr19:1856969-1857049 1.0000 80 chr17:45727795-45727875 1.0000 80 chr22:20778676-20778756 1.0000 80 chr6:32143651-32143731 1.0000 80 chr3:140661054-140661134 1.0000 80 chr19:4328504-4328584 1.0000 80 chr6:74230216-74230296 1.0000 80 chr3:50654554-50654634 1.0000 80 chr1:167906259-167906339 1.0000 80 chr1:30558908-30558988 1.0000 80 chr17:42297484-42297564 1.0000 80 chr14:88237680-88237760 1.0000 80 chr10:75634135-75634215 1.0000 80 chr15:75165681-75165761 1.0000 80 chr3:42696368-42696448 1.0000 80 chr6:53171164-53171244 1.0000 80 chr4:6784301-6784381 1.0000 80 chr2:73511546-73511626 1.0000 80 chr10:60095101-60095181 1.0000 80 chr19:45999832-45999912 1.0000 80 chr9:86237993-86238073 1.0000 80 chr17:74137450-74137530 1.0000 80 chr7:105162271-105162351 1.0000 80 chr21:40050904-40050984 1.0000 80 chr6:49483526-49483606 1.0000 80 chr13:50366782-50366862 1.0000 80 chr11:65190871-65190951 1.0000 80 chr17:47755318-47755398 1.0000 80 chr1:53018677-53018757 1.0000 80 chr12:53297391-53297471 1.0000 80 chr2:27938557-27938637 1.0000 80 chr7:152409674-152409754 1.0000 80 chr1:7765242-7765322 1.0000 80 chr1:6052110-6052190 1.0000 80 chr20:61640578-61640658 1.0000 80 ******************************************************************************** ******************************************************************************** COMMAND LINE SUMMARY ******************************************************************************** This information can also be useful in the event you wish to report a problem with the MEME software. command: meme -oc ../result/final_prediction/K562/inference_raw/MEME/RankLinear0.6_40_PCBP1/ -dna -nmotifs 5 -w 8 -maxsize 250000 -nostatus ../result/final_prediction/K562/fasta/RankLinear0.6_40/PCBP1.fasta model: mod= zoops nmotifs= 5 evt= inf objective function: em= E-value of product of p-values starts= E-value of product of p-values strands: + width: minw= 8 maxw= 8 nsites: minsites= 2 maxsites= 250 wnsites= 0.8 theta: spmap= uni spfuzz= 0.5 em: prior= dirichlet b= 0.01 maxiter= 50 distance= 1e-05 trim: wg= 11 ws= 1 endgaps= yes data: n= 20000 N= 250 sample: seed= 0 hsfrac= 0 searchsize= 20000 norand= no csites= 1000 Letter frequencies in dataset: A 0.181 C 0.319 G 0.319 T 0.181 Background letter frequencies (from file dataset with add-one prior applied): A 0.181 C 0.319 G 0.319 T 0.181 Background model order: 0 ******************************************************************************** ******************************************************************************** MOTIF AAAGAAAA MEME-1 width = 8 sites = 43 llr = 375 E-value = 1.6e-017 ******************************************************************************** -------------------------------------------------------------------------------- Motif AAAGAAAA MEME-1 Description -------------------------------------------------------------------------------- Simplified A a78199a6 pos.-specific C :::1:::1 probability G ::161::: matrix T :313:1:3 bits 2.5 2.2 * * 2.0 * * * 1.7 * *** Relative 1.5 * * *** Entropy 1.2 *** **** (12.6 bits) 1.0 *** **** 0.7 *** **** 0.5 ******** 0.2 ******** 0.0 -------- Multilevel AAAGAAAA consensus T T T sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAAGAAAA MEME-1 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr7:138087653-138087733 9 2.03e-06 ggagggga AAAGAAAA GAAGGGAAGA chr16:46612217-46612297 14 2.03e-06 aggggaaAAG AAAGAAAA CAGAACTCAT chr10:73958149-73958229 21 2.03e-06 ggaaggaagg aaagaaaa gAAAGAAAGA chr19:55646213-55646293 30 2.03e-06 GAAAAGGAAG AAAGAAAA GACCgagccc chr22:20767577-20767657 11 2.03e-06 aaaaagaaaa aaagaaaa gaaaagaaaa chr1:32273032-32273112 37 2.03e-06 cagataggtc aaagaaaa attgtaatta chr11:34006997-34007077 58 2.03e-06 TAGGTAGGTT AAAGAAAA ATATTAACTT chr8:79100825-79100905 69 3.18e-06 attaaattat aaataaaa cata chr5:108676228-108676308 36 3.18e-06 GAGAAGACTG AAATAAAA CACTTCCTTT chr5:44888712-44888792 5 7.24e-06 TCTT ATAGAAAA AAATGAATTA chr17:44202476-44202556 13 7.24e-06 ggagggaggg aaagaaat tgccacagct chr10:70262768-70262848 13 7.24e-06 aaggagaAGG AAAGAAAT TGCTAATCAT chr10:63491548-63491628 55 9.55e-06 CCTCAAAGTC ATATAAAA TCCAGCAGAA chr5:130614326-130614406 39 1.07e-05 ttttatagac aaaaaaaa tgcttgaata chr6:165038109-165038189 6 1.27e-05 aatat atagaaat aaagttaaat chr5:44779421-44779501 11 2.14e-05 TGTAACCAGT AAAGATAA ATTAGAAATT chr1:25056852-25056932 67 2.14e-05 ACAAGGTGGG AAAAAAAT AAGTGT chr1:21713382-21713462 20 2.34e-05 ttcatctcaa aaacaaaa caggatgcag chr4:94370181-94370261 69 3.45e-05 TTGTAATATT ATTTAAAA GCCA chr16:78638472-78638552 68 3.45e-05 tttaATAAAG ATTTAAAA AAGAt chr1:221873484-221873564 71 3.45e-05 agagggaggg aaggaaaa gg chr8:130491160-130491240 72 5.06e-05 TATTAAGATA ATACAAAA T chr3:185083562-185083642 11 5.49e-05 AAAATGCCGG AAATAAAC TTCAGTATTA chr15:90545207-90545287 32 5.85e-05 gGCAAAAATG AAAGGAAA GCGTCgcggc chr11:77489345-77489425 8 6.32e-05 AGGCTTT AGAGAAAA ACAATGTTCC chr5:42978705-42978785 53 6.73e-05 tcttagtagt attgaaat aacgacacat chr8:4032310-4032390 67 6.93e-05 TCAAAATTTC AGATAAAA TATTGA chr6:53171164-53171244 63 7.76e-05 TTAAACATTC AAGGAAAT TTCTTCCCCA chr3:130355483-130355563 30 8.68e-05 ATCTTTATGT ATAGATAT TACTTGTGTA chr6:166815843-166815923 4 8.68e-05 tGT ATAGATAT AGATATATAc chr15:102033471-10203355 16 8.68e-05 CAGGGCCAAG ATAGAAAC CTGATGATTC chr7:128341273-128341353 10 9.92e-05 aaatgttag aagtaaat gctcgcttcc chr6:50603335-50603415 63 9.92e-05 TCTATATGTC AATAAAAT CTTAATAAGA chr8:68252035-68252115 52 9.92e-05 AAGTCTGACA TAAGAAAA TTTGAAAAAC chr18:29616631-29616711 27 1.18e-04 TTTTATAGGG AATTATAA TGTGTCTGGT chr11:4637239-4637319 11 1.18e-04 agagatcttt aaaggaat tgagacccag chr2:163605220-163605300 47 1.32e-04 AACAAAGGAG ATATGAAA CTAACAAAGC chr2:170595244-170595324 14 1.38e-04 AAGTTAGTGG AAAGACAA AACCAACGTT chr7:152190728-152190808 5 1.54e-04 AGGA AAAGAAGT TTGAGATTTC chr7:158424609-158424689 49 1.69e-04 ACTGCCAGGC AATGAAAC GTGCTCACTG chr7:130895530-130895610 72 1.77e-04 GACCATCAAC ATATAAGA C chr11:65192506-65192586 56 1.95e-04 TGGGTGAGCC AAGAAAAT ACTAATTAAT chr9:37286676-37286756 1 2.29e-04 . atacataa atgtttaact -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAAGAAAA MEME-1 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr7:138087653-138087733 2e-06 8_[+1]_64 chr16:46612217-46612297 2e-06 13_[+1]_59 chr10:73958149-73958229 2e-06 20_[+1]_52 chr19:55646213-55646293 2e-06 29_[+1]_43 chr22:20767577-20767657 2e-06 10_[+1]_62 chr1:32273032-32273112 2e-06 36_[+1]_36 chr11:34006997-34007077 2e-06 57_[+1]_15 chr8:79100825-79100905 3.2e-06 68_[+1]_4 chr5:108676228-108676308 3.2e-06 35_[+1]_37 chr5:44888712-44888792 7.2e-06 4_[+1]_68 chr17:44202476-44202556 7.2e-06 12_[+1]_60 chr10:70262768-70262848 7.2e-06 12_[+1]_60 chr10:63491548-63491628 9.5e-06 54_[+1]_18 chr5:130614326-130614406 1.1e-05 38_[+1]_34 chr6:165038109-165038189 1.3e-05 5_[+1]_67 chr5:44779421-44779501 2.1e-05 10_[+1]_62 chr1:25056852-25056932 2.1e-05 66_[+1]_6 chr1:21713382-21713462 2.3e-05 19_[+1]_53 chr4:94370181-94370261 3.5e-05 68_[+1]_4 chr16:78638472-78638552 3.5e-05 67_[+1]_5 chr1:221873484-221873564 3.5e-05 70_[+1]_2 chr8:130491160-130491240 5.1e-05 71_[+1]_1 chr3:185083562-185083642 5.5e-05 10_[+1]_62 chr15:90545207-90545287 5.8e-05 31_[+1]_41 chr11:77489345-77489425 6.3e-05 7_[+1]_65 chr5:42978705-42978785 6.7e-05 52_[+1]_20 chr8:4032310-4032390 6.9e-05 66_[+1]_6 chr6:53171164-53171244 7.8e-05 62_[+1]_10 chr3:130355483-130355563 8.7e-05 29_[+1]_43 chr6:166815843-166815923 8.7e-05 3_[+1]_69 chr15:102033471-10203355 8.7e-05 15_[+1]_57 chr7:128341273-128341353 9.9e-05 9_[+1]_63 chr6:50603335-50603415 9.9e-05 62_[+1]_10 chr8:68252035-68252115 9.9e-05 51_[+1]_21 chr18:29616631-29616711 0.00012 26_[+1]_46 chr11:4637239-4637319 0.00012 10_[+1]_62 chr2:163605220-163605300 0.00013 46_[+1]_26 chr2:170595244-170595324 0.00014 13_[+1]_59 chr7:152190728-152190808 0.00015 4_[+1]_68 chr7:158424609-158424689 0.00017 48_[+1]_24 chr7:130895530-130895610 0.00018 71_[+1]_1 chr11:65192506-65192586 0.0002 55_[+1]_17 chr9:37286676-37286756 0.00023 [+1]_72 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAAGAAAA MEME-1 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF AAAGAAAA width=8 seqs=43 chr7:138087653-138087733 ( 9) AAAGAAAA 1 chr16:46612217-46612297 ( 14) AAAGAAAA 1 chr10:73958149-73958229 ( 21) AAAGAAAA 1 chr19:55646213-55646293 ( 30) AAAGAAAA 1 chr22:20767577-20767657 ( 11) AAAGAAAA 1 chr1:32273032-32273112 ( 37) AAAGAAAA 1 chr11:34006997-34007077 ( 58) AAAGAAAA 1 chr8:79100825-79100905 ( 69) AAATAAAA 1 chr5:108676228-108676308 ( 36) AAATAAAA 1 chr5:44888712-44888792 ( 5) ATAGAAAA 1 chr17:44202476-44202556 ( 13) AAAGAAAT 1 chr10:70262768-70262848 ( 13) AAAGAAAT 1 chr10:63491548-63491628 ( 55) ATATAAAA 1 chr5:130614326-130614406 ( 39) AAAAAAAA 1 chr6:165038109-165038189 ( 6) ATAGAAAT 1 chr5:44779421-44779501 ( 11) AAAGATAA 1 chr1:25056852-25056932 ( 67) AAAAAAAT 1 chr1:21713382-21713462 ( 20) AAACAAAA 1 chr4:94370181-94370261 ( 69) ATTTAAAA 1 chr16:78638472-78638552 ( 68) ATTTAAAA 1 chr1:221873484-221873564 ( 71) AAGGAAAA 1 chr8:130491160-130491240 ( 72) ATACAAAA 1 chr3:185083562-185083642 ( 11) AAATAAAC 1 chr15:90545207-90545287 ( 32) AAAGGAAA 1 chr11:77489345-77489425 ( 8) AGAGAAAA 1 chr5:42978705-42978785 ( 53) ATTGAAAT 1 chr8:4032310-4032390 ( 67) AGATAAAA 1 chr6:53171164-53171244 ( 63) AAGGAAAT 1 chr3:130355483-130355563 ( 30) ATAGATAT 1 chr6:166815843-166815923 ( 4) ATAGATAT 1 chr15:102033471-10203355 ( 16) ATAGAAAC 1 chr7:128341273-128341353 ( 10) AAGTAAAT 1 chr6:50603335-50603415 ( 63) AATAAAAT 1 chr8:68252035-68252115 ( 52) TAAGAAAA 1 chr18:29616631-29616711 ( 27) AATTATAA 1 chr11:4637239-4637319 ( 11) AAAGGAAT 1 chr2:163605220-163605300 ( 47) ATATGAAA 1 chr2:170595244-170595324 ( 14) AAAGACAA 1 chr7:152190728-152190808 ( 5) AAAGAAGT 1 chr7:158424609-158424689 ( 49) AATGAAAC 1 chr7:130895530-130895610 ( 72) ATATAAGA 1 chr11:65192506-65192586 ( 56) AAGAAAAT 1 chr9:37286676-37286756 ( 1) ATACATAA 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAAGAAAA MEME-1 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 10.2475 E= 1.6e-017 244 -1207 -1207 -296 185 -1207 -278 74 209 -1207 -178 -37 -96 -219 86 50 236 -1207 -219 -1207 225 -378 -1207 -64 240 -1207 -278 -1207 180 -219 -1207 74 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAAGAAAA MEME-1 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 43 E= 1.6e-017 0.976744 0.000000 0.000000 0.023256 0.651163 0.000000 0.046512 0.302326 0.767442 0.000000 0.093023 0.139535 0.093023 0.069767 0.581395 0.255814 0.930233 0.000000 0.069767 0.000000 0.860465 0.023256 0.000000 0.116279 0.953488 0.000000 0.046512 0.000000 0.627907 0.069767 0.000000 0.302326 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAAGAAAA MEME-1 regular expression -------------------------------------------------------------------------------- A[AT]A[GT]AAA[AT] -------------------------------------------------------------------------------- Time 5.19 secs. ******************************************************************************** ******************************************************************************** MOTIF TTTTHWWA MEME-2 width = 8 sites = 33 llr = 293 E-value = 6.6e-008 ******************************************************************************** -------------------------------------------------------------------------------- Motif TTTTHWWA MEME-2 Description -------------------------------------------------------------------------------- Simplified A ::124657 pos.-specific C ::1:4:2: probability G :::::::: matrix T aa882433 bits 2.5 ** 2.2 ** 2.0 ** 1.7 ** * * Relative 1.5 **** * * Entropy 1.2 **** * * (12.8 bits) 1.0 **** * * 0.7 **** *** 0.5 ******** 0.2 ******** 0.0 -------- Multilevel TTTTAAAA consensus CTTT sequence T C -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTTTHWWA MEME-2 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr21:40050904-40050984 44 1.15e-06 GAATTTCTAC TTTTAAAA TTCTGGGTAA chr6:49483526-49483606 14 2.30e-06 GGTAATGGTA TTTTATAA TCATAGTAGC chr7:77396247-77396327 40 5.49e-06 TCAAGTTTAA TTTTCAAA GCACATGAAC chr11:34006997-34007077 33 5.49e-06 ATTAAACATC TTTTCAAA GAACCCATAG chr10:63491548-63491628 21 6.64e-06 gaAAGTTTCT TTTTTAAA GGGAGATCTT chr4:175145847-175145927 43 6.64e-06 agctgtccgg tttttaaa gccaaaaatc chr5:44888712-44888792 64 7.79e-06 GGCTGATTAG TTTTATTA TTTTctccc chr8:68252035-68252115 14 1.21e-05 GGATTCTTTC TTTTTTAA CCATTCTTTA chr1:32273032-32273112 17 1.21e-05 gggaagggac ttttaaat aacagatagg chr5:130614326-130614406 28 1.53e-05 gaaattgttg tttttata gacaaaaaaa chr18:29616631-29616711 71 1.85e-05 CTTCCTGCTA TTTTCTTA TG chr5:42978705-42978785 40 1.85e-05 attagcagat ttttctta gtagtattga chr2:61698182-61698262 18 2.40e-05 GCCGCCGCCA TTTTAACA GAGCGCTCGG chr2:3738086-3738166 25 2.40e-05 tgatagtatg ttttaatt gacttttatt chr16:78638472-78638552 58 3.15e-05 taccatttcc tttaATAA AGATTTAAAA chr7:152409674-152409754 7 3.47e-05 CCTCTG TTTTCTAT TAATGACCAA chr16:46612217-46612297 46 3.47e-05 TCAAGAAACC TTATAAAA GTAAGAAATG chr5:108676228-108676308 55 3.70e-05 ACTTCCTTTA TTTAAATA ATTCAAATAT chr9:139591195-139591275 60 5.01e-05 CCCAAAGATG TTTTTATT CAGATTGCAA chr11:77489345-77489425 35 6.00e-05 CTAGCGGTGT TTTACTAA GACTGGGTCC chr6:44010163-44010243 37 6.00e-05 GACCTTTGGC TTTTCTTT GAGGGCTGCA chr7:128341273-128341353 57 6.00e-05 caggcaaaag ttttctca gcaaggcagt chr8:79100825-79100905 43 6.96e-05 aagatagatc tttaaaat atcaagtcat chr21:47843802-47843882 43 6.96e-05 CACAAGGAGT TTTTTTCA TGGATGTCTC chr6:159364585-159364665 8 6.96e-05 agcagaa ttatcaaa ctcagaaaat chr4:151579571-151579651 11 9.10e-05 TGTTATCAAG TTATCATA ATACTTAGCA chr6:24238433-24238513 2 1.04e-04 C TTCTAAAA CCACTGATTG chr10:70262768-70262848 55 1.04e-04 AATGCAACTA TTTTTACT GTATAGGAGC chr7:150342888-150342968 48 1.20e-04 ccttcacagg ttttctct tccctttcct chr1:27320085-27320165 64 1.28e-04 CCGCCCCGTG TTCTATAA GATGCGCGG chr4:94370181-94370261 53 1.34e-04 ACCTGGAATC TTTACATT GTAATATTAT chr5:68264382-68264462 40 1.34e-04 cacaggattc tttacaca ggcaaatagg chr6:165038109-165038189 37 1.44e-04 aatattaaac ttatatca tgtggtctta -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTTTHWWA MEME-2 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr21:40050904-40050984 1.2e-06 43_[+2]_29 chr6:49483526-49483606 2.3e-06 13_[+2]_59 chr7:77396247-77396327 5.5e-06 39_[+2]_33 chr11:34006997-34007077 5.5e-06 32_[+2]_40 chr10:63491548-63491628 6.6e-06 20_[+2]_52 chr4:175145847-175145927 6.6e-06 42_[+2]_30 chr5:44888712-44888792 7.8e-06 63_[+2]_9 chr8:68252035-68252115 1.2e-05 13_[+2]_59 chr1:32273032-32273112 1.2e-05 16_[+2]_56 chr5:130614326-130614406 1.5e-05 27_[+2]_45 chr18:29616631-29616711 1.8e-05 70_[+2]_2 chr5:42978705-42978785 1.8e-05 39_[+2]_33 chr2:61698182-61698262 2.4e-05 17_[+2]_55 chr2:3738086-3738166 2.4e-05 24_[+2]_48 chr16:78638472-78638552 3.1e-05 57_[+2]_15 chr7:152409674-152409754 3.5e-05 6_[+2]_66 chr16:46612217-46612297 3.5e-05 45_[+2]_27 chr5:108676228-108676308 3.7e-05 54_[+2]_18 chr9:139591195-139591275 5e-05 59_[+2]_13 chr11:77489345-77489425 6e-05 34_[+2]_38 chr6:44010163-44010243 6e-05 36_[+2]_36 chr7:128341273-128341353 6e-05 56_[+2]_16 chr8:79100825-79100905 7e-05 42_[+2]_30 chr21:47843802-47843882 7e-05 42_[+2]_30 chr6:159364585-159364665 7e-05 7_[+2]_65 chr4:151579571-151579651 9.1e-05 10_[+2]_62 chr6:24238433-24238513 0.0001 1_[+2]_71 chr10:70262768-70262848 0.0001 54_[+2]_18 chr7:150342888-150342968 0.00012 47_[+2]_25 chr1:27320085-27320165 0.00013 63_[+2]_9 chr4:94370181-94370261 0.00013 52_[+2]_20 chr5:68264382-68264462 0.00013 39_[+2]_33 chr6:165038109-165038189 0.00014 36_[+2]_36 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTTTHWWA MEME-2 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF TTTTHWWA width=8 seqs=33 chr21:40050904-40050984 ( 44) TTTTAAAA 1 chr6:49483526-49483606 ( 14) TTTTATAA 1 chr7:77396247-77396327 ( 40) TTTTCAAA 1 chr11:34006997-34007077 ( 33) TTTTCAAA 1 chr10:63491548-63491628 ( 21) TTTTTAAA 1 chr4:175145847-175145927 ( 43) TTTTTAAA 1 chr5:44888712-44888792 ( 64) TTTTATTA 1 chr8:68252035-68252115 ( 14) TTTTTTAA 1 chr1:32273032-32273112 ( 17) TTTTAAAT 1 chr5:130614326-130614406 ( 28) TTTTTATA 1 chr18:29616631-29616711 ( 71) TTTTCTTA 1 chr5:42978705-42978785 ( 40) TTTTCTTA 1 chr2:61698182-61698262 ( 18) TTTTAACA 1 chr2:3738086-3738166 ( 25) TTTTAATT 1 chr16:78638472-78638552 ( 58) TTTAATAA 1 chr7:152409674-152409754 ( 7) TTTTCTAT 1 chr16:46612217-46612297 ( 46) TTATAAAA 1 chr5:108676228-108676308 ( 55) TTTAAATA 1 chr9:139591195-139591275 ( 60) TTTTTATT 1 chr11:77489345-77489425 ( 35) TTTACTAA 1 chr6:44010163-44010243 ( 37) TTTTCTTT 1 chr7:128341273-128341353 ( 57) TTTTCTCA 1 chr8:79100825-79100905 ( 43) TTTAAAAT 1 chr21:47843802-47843882 ( 43) TTTTTTCA 1 chr6:159364585-159364665 ( 8) TTATCAAA 1 chr4:151579571-151579651 ( 11) TTATCATA 1 chr6:24238433-24238513 ( 2) TTCTAAAA 1 chr10:70262768-70262848 ( 55) TTTTTACT 1 chr7:150342888-150342968 ( 48) TTTTCTCT 1 chr1:27320085-27320165 ( 64) TTCTATAA 1 chr4:94370181-94370261 ( 53) TTTACATT 1 chr5:68264382-68264462 ( 40) TTTACACA 1 chr6:165038109-165038189 ( 37) TTATATCA 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTTTHWWA MEME-2 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 11.1193 E= 6.6e-008 -1169 -1169 -1169 247 -1169 -1169 -1169 247 -57 -240 -1169 218 1 -1169 -1169 218 113 30 -1169 23 167 -1169 -1169 123 142 -59 -1169 74 201 -1169 -1169 59 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTTTHWWA MEME-2 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 33 E= 6.6e-008 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.121212 0.060606 0.000000 0.818182 0.181818 0.000000 0.000000 0.818182 0.393939 0.393939 0.000000 0.212121 0.575758 0.000000 0.000000 0.424242 0.484848 0.212121 0.000000 0.303030 0.727273 0.000000 0.000000 0.272727 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTTTHWWA MEME-2 regular expression -------------------------------------------------------------------------------- TTTT[ACT][AT][ATC][AT] -------------------------------------------------------------------------------- Time 9.04 secs. ******************************************************************************** ******************************************************************************** MOTIF WDAAAWTR MEME-3 width = 8 sites = 24 llr = 212 E-value = 1.3e+001 ******************************************************************************** -------------------------------------------------------------------------------- Motif WDAAAWTR MEME-3 Description -------------------------------------------------------------------------------- Simplified A 6389a4:6 pos.-specific C :::::::: probability G :52::::3 matrix T 43:1:6a1 bits 2.5 * 2.2 * * 2.0 ** * 1.7 *** * Relative 1.5 * ***** Entropy 1.2 * ***** (12.7 bits) 1.0 * ****** 0.7 * ****** 0.5 ******** 0.2 ******** 0.0 -------- Multilevel AGAAATTA consensus TT A G sequence A -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif WDAAAWTR MEME-3 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr8:4032310-4032390 39 3.18e-06 TGTGTGCCAG AGAAATTA CACCTTCGCC chr5:44779421-44779501 22 3.18e-06 AAGATAAATT AGAAATTA CAAGGAGGAA chr8:79100825-79100905 60 5.49e-06 tatcaagtca ttaaatta taaataaaac chr11:77489345-77489425 72 7.52e-06 TCATAAAACA TGAAATTA A chr6:50603335-50603415 35 9.82e-06 AGAATTACCT ATAAAATA AGTGAACTAA chr1:32273032-32273112 61 9.82e-06 attaaaaatg ataaaata ttgagattga chr7:128341273-128341353 34 1.62e-05 ttccaccaag tgaaaata gcactcaggc chr10:63491548-63491628 69 2.29e-05 AAAATCCAGC AGAAATTG CTTC chr5:130614326-130614406 17 3.38e-05 tgggaccata tgaaattg ttgtttttat chr21:40050904-40050984 59 3.90e-05 AAATTCTGGG TAAAATTG TATTCCCCCA chr18:29616631-29616711 8 4.37e-05 gggaagg agAAAATG GTTTTATAGG chr6:165038109-165038189 18 4.37e-05 agaaataaag ttaaattt gaatattaaa chr22:20767577-20767657 23 4.37e-05 agaaaagaaa agaaaaTG CACAGTGAGT chr7:138087653-138087733 58 5.33e-05 ACTCCGCAAA ATAAAATT CCTGTTACTT chr6:159364585-159364665 19 6.09e-05 tatcaaactc agaaaatt taacactcat chr5:44888712-44888792 15 6.73e-05 ATAGAAAAAA ATGAATTA ATTGCTTTTT chr7:77396247-77396327 8 6.73e-05 AATTACC AAATATTA CTTAAATGGT chr1:25056852-25056932 40 6.73e-05 AAGCCTCACC TAAAAATG AAGAGGCAAA chr1:42687793-42687873 7 7.31e-05 AAAATA AGGAATTA CTGTCTTTCT chr8:130491160-130491240 59 7.92e-05 GATAAGATCC TGATATTA AGATAATACA chr3:185083562-185083642 27 9.55e-05 ACTTCAGTAT TAGAATTA CCTGTGGAAC chr11:65192506-65192586 70 1.08e-04 AAATACTAAT TAATAATA GTA chr14:88237680-88237760 23 1.29e-04 TCAGCCCGGA ATGAATTG GGATCCCCAG chr10:32144088-32144168 72 1.29e-04 GAAGACTGGG AAAATTTA G -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif WDAAAWTR MEME-3 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr8:4032310-4032390 3.2e-06 38_[+3]_34 chr5:44779421-44779501 3.2e-06 21_[+3]_51 chr8:79100825-79100905 5.5e-06 59_[+3]_13 chr11:77489345-77489425 7.5e-06 71_[+3]_1 chr6:50603335-50603415 9.8e-06 34_[+3]_38 chr1:32273032-32273112 9.8e-06 60_[+3]_12 chr7:128341273-128341353 1.6e-05 33_[+3]_39 chr10:63491548-63491628 2.3e-05 68_[+3]_4 chr5:130614326-130614406 3.4e-05 16_[+3]_56 chr21:40050904-40050984 3.9e-05 58_[+3]_14 chr18:29616631-29616711 4.4e-05 7_[+3]_65 chr6:165038109-165038189 4.4e-05 17_[+3]_55 chr22:20767577-20767657 4.4e-05 22_[+3]_50 chr7:138087653-138087733 5.3e-05 57_[+3]_15 chr6:159364585-159364665 6.1e-05 18_[+3]_54 chr5:44888712-44888792 6.7e-05 14_[+3]_58 chr7:77396247-77396327 6.7e-05 7_[+3]_65 chr1:25056852-25056932 6.7e-05 39_[+3]_33 chr1:42687793-42687873 7.3e-05 6_[+3]_66 chr8:130491160-130491240 7.9e-05 58_[+3]_14 chr3:185083562-185083642 9.6e-05 26_[+3]_46 chr11:65192506-65192586 0.00011 69_[+3]_3 chr14:88237680-88237760 0.00013 22_[+3]_50 chr10:32144088-32144168 0.00013 71_[+3]_1 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif WDAAAWTR MEME-3 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF WDAAAWTR width=8 seqs=24 chr8:4032310-4032390 ( 39) AGAAATTA 1 chr5:44779421-44779501 ( 22) AGAAATTA 1 chr8:79100825-79100905 ( 60) TTAAATTA 1 chr11:77489345-77489425 ( 72) TGAAATTA 1 chr6:50603335-50603415 ( 35) ATAAAATA 1 chr1:32273032-32273112 ( 61) ATAAAATA 1 chr7:128341273-128341353 ( 34) TGAAAATA 1 chr10:63491548-63491628 ( 69) AGAAATTG 1 chr5:130614326-130614406 ( 17) TGAAATTG 1 chr21:40050904-40050984 ( 59) TAAAATTG 1 chr18:29616631-29616711 ( 8) AGAAAATG 1 chr6:165038109-165038189 ( 18) TTAAATTT 1 chr22:20767577-20767657 ( 23) AGAAAATG 1 chr7:138087653-138087733 ( 58) ATAAAATT 1 chr6:159364585-159364665 ( 19) AGAAAATT 1 chr5:44888712-44888792 ( 15) ATGAATTA 1 chr7:77396247-77396327 ( 8) AAATATTA 1 chr1:25056852-25056932 ( 40) TAAAAATG 1 chr1:42687793-42687873 ( 7) AGGAATTA 1 chr8:130491160-130491240 ( 59) TGATATTA 1 chr3:185083562-185083642 ( 27) TAGAATTA 1 chr11:65192506-65192586 ( 70) TAATAATA 1 chr14:88237680-88237760 ( 23) ATGAATTG 1 chr10:32144088-32144168 ( 72) AAAATTTA 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif WDAAAWTR MEME-3 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 11.477 E= 1.3e+001 169 -1123 -1123 120 47 -1123 52 69 221 -1123 -94 -1123 228 -1123 -1123 -53 241 -1123 -1123 -212 105 -1123 -1123 179 -1123 -1123 -1123 247 169 -1123 -13 -53 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif WDAAAWTR MEME-3 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 24 E= 1.3e+001 0.583333 0.000000 0.000000 0.416667 0.250000 0.000000 0.458333 0.291667 0.833333 0.000000 0.166667 0.000000 0.875000 0.000000 0.000000 0.125000 0.958333 0.000000 0.000000 0.041667 0.375000 0.000000 0.000000 0.625000 0.000000 0.000000 0.000000 1.000000 0.583333 0.000000 0.291667 0.125000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif WDAAAWTR MEME-3 regular expression -------------------------------------------------------------------------------- [AT][GTA]AAA[TA]T[AG] -------------------------------------------------------------------------------- Time 12.87 secs. ******************************************************************************** ******************************************************************************** MOTIF TCCCYTCC MEME-4 width = 8 sites = 33 llr = 287 E-value = 1.2e-004 ******************************************************************************** -------------------------------------------------------------------------------- Motif TCCCYTCC MEME-4 Description -------------------------------------------------------------------------------- Simplified A :::::::: pos.-specific C :8a83:8a probability G :::::::: matrix T a2:27a2: bits 2.5 * 2.2 * * 2.0 * * 1.7 * * * * Relative 1.5 * * * * Entropy 1.2 *** **** (12.6 bits) 1.0 ******** 0.7 ******** 0.5 ******** 0.2 ******** 0.0 -------- Multilevel TCCCTTCC consensus TC sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCCCYTCC MEME-4 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr7:152409674-152409754 66 1.96e-05 tcctttccct tcccttcc cttcctt chr2:55711202-55711282 67 1.96e-05 tcccttccct tcccttcc cttccc chr1:2332594-2332674 71 1.96e-05 tccctcctcc tcccttcc tc chr5:34698255-34698335 35 1.96e-05 cttcccctcc tcccttcc cctccctctc chr3:185083562-185083642 50 1.96e-05 GGAACCTTTT Tcccttcc ctccctacct chr11:4637239-4637319 63 1.96e-05 ctttattggt tcccttcc cttcccctct chr6:34941753-34941833 46 1.96e-05 ctcttccctt tcccttcc cttccccttc chr21:38411957-38412037 66 1.96e-05 cccttccctc tcccttcc ctctccc chr4:94369979-94370059 36 1.96e-05 cccttcccct tcccttcc ccttcccttc chr1:235575337-235575417 73 1.96e-05 tctccaagtt tcccttcc chr16:23993262-23993342 44 1.96e-05 cccttccctt tcccttcc ttttcccttc chr2:3737792-3737872 49 1.96e-05 cccctcccct tcccttcc cttccctccc chr7:77396247-77396327 73 3.07e-05 GCATTATttc tcctttcc chr6:165038109-165038189 71 3.07e-05 tcacctatcc tcctttcc cc chr5:130614326-130614406 70 3.07e-05 gcagttccTT tcctttcc tct chr5:15411132-15411212 67 5.29e-05 AACTcctgtc tccctttc tctctt chr7:150342888-150342968 56 5.29e-05 ggttttctct tccctttc ctctctttTt chr1:241838429-241838509 57 5.29e-05 ccttccttct ttccttcc tcccaacttc chr3:38495246-38495326 72 8.75e-05 AGGGCCCGCC TCCCCTCC C chr19:35759842-35759922 35 8.75e-05 ATCTCCTCCG TCCCCTCC TGCCGCGCGG chr4:1769012-1769092 67 8.75e-05 GGGGCGGGTc tcccctcc tccctc chr5:180527779-180527859 72 8.75e-05 TGGGGtcccg tcccctcc c chr4:726015-726095 22 8.75e-05 GGGCTCCCCC TCCCCTCC CGAGTGGGCG chr22:38901870-38901950 64 1.26e-04 GCCAGGCCTC TCCTCTCC TCCCCCACC chr15:102033471-10203355 42 1.26e-04 TCCTTGCTGT TCCTCTCC ATGGTGGGTT chr2:170595244-170595324 61 1.26e-04 ATCATCTTTC TTCCTTTC TTCATCTTCC chr16:88857800-88857880 18 1.26e-04 GTAAACATCC TCCTCTCC CACCCACCTG chr11:65601036-65601116 4 1.65e-04 cct tccccttc cccttcccca chr1:182992134-182992214 60 1.65e-04 GAGGCCGCCC TTCCCTCC CGGCATGCAC chr21:47580943-47581023 37 1.65e-04 CCTTCCTGGC TTCCCTCC TTGAGCACCG chr6:49483526-49483606 69 1.69e-04 CACCATTCAT TTCTTTTC TTTC chr5:34698048-34698128 70 1.69e-04 ttatTGCTGA TTCTTTTC TCC chr2:230786721-230786801 39 2.43e-04 CCGTGCCGCC TCCCTCCC CGCCTGCTCT -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCCCYTCC MEME-4 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr7:152409674-152409754 2e-05 65_[+4]_7 chr2:55711202-55711282 2e-05 66_[+4]_6 chr1:2332594-2332674 2e-05 70_[+4]_2 chr5:34698255-34698335 2e-05 34_[+4]_38 chr3:185083562-185083642 2e-05 49_[+4]_23 chr11:4637239-4637319 2e-05 62_[+4]_10 chr6:34941753-34941833 2e-05 45_[+4]_27 chr21:38411957-38412037 2e-05 65_[+4]_7 chr4:94369979-94370059 2e-05 35_[+4]_37 chr1:235575337-235575417 2e-05 72_[+4] chr16:23993262-23993342 2e-05 43_[+4]_29 chr2:3737792-3737872 2e-05 48_[+4]_24 chr7:77396247-77396327 3.1e-05 72_[+4] chr6:165038109-165038189 3.1e-05 70_[+4]_2 chr5:130614326-130614406 3.1e-05 69_[+4]_3 chr5:15411132-15411212 5.3e-05 66_[+4]_6 chr7:150342888-150342968 5.3e-05 55_[+4]_17 chr1:241838429-241838509 5.3e-05 56_[+4]_16 chr3:38495246-38495326 8.7e-05 71_[+4]_1 chr19:35759842-35759922 8.7e-05 34_[+4]_38 chr4:1769012-1769092 8.7e-05 66_[+4]_6 chr5:180527779-180527859 8.7e-05 71_[+4]_1 chr4:726015-726095 8.7e-05 21_[+4]_51 chr22:38901870-38901950 0.00013 63_[+4]_9 chr15:102033471-10203355 0.00013 41_[+4]_31 chr2:170595244-170595324 0.00013 60_[+4]_12 chr16:88857800-88857880 0.00013 17_[+4]_55 chr11:65601036-65601116 0.00017 3_[+4]_69 chr1:182992134-182992214 0.00017 59_[+4]_13 chr21:47580943-47581023 0.00017 36_[+4]_36 chr6:49483526-49483606 0.00017 68_[+4]_4 chr5:34698048-34698128 0.00017 69_[+4]_3 chr2:230786721-230786801 0.00024 38_[+4]_34 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCCCYTCC MEME-4 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF TCCCYTCC width=8 seqs=33 chr7:152409674-152409754 ( 66) TCCCTTCC 1 chr2:55711202-55711282 ( 67) TCCCTTCC 1 chr1:2332594-2332674 ( 71) TCCCTTCC 1 chr5:34698255-34698335 ( 35) TCCCTTCC 1 chr3:185083562-185083642 ( 50) TCCCTTCC 1 chr11:4637239-4637319 ( 63) TCCCTTCC 1 chr6:34941753-34941833 ( 46) TCCCTTCC 1 chr21:38411957-38412037 ( 66) TCCCTTCC 1 chr4:94369979-94370059 ( 36) TCCCTTCC 1 chr1:235575337-235575417 ( 73) TCCCTTCC 1 chr16:23993262-23993342 ( 44) TCCCTTCC 1 chr2:3737792-3737872 ( 49) TCCCTTCC 1 chr7:77396247-77396327 ( 73) TCCTTTCC 1 chr6:165038109-165038189 ( 71) TCCTTTCC 1 chr5:130614326-130614406 ( 70) TCCTTTCC 1 chr5:15411132-15411212 ( 67) TCCCTTTC 1 chr7:150342888-150342968 ( 56) TCCCTTTC 1 chr1:241838429-241838509 ( 57) TTCCTTCC 1 chr3:38495246-38495326 ( 72) TCCCCTCC 1 chr19:35759842-35759922 ( 35) TCCCCTCC 1 chr4:1769012-1769092 ( 67) TCCCCTCC 1 chr5:180527779-180527859 ( 72) TCCCCTCC 1 chr4:726015-726095 ( 22) TCCCCTCC 1 chr22:38901870-38901950 ( 64) TCCTCTCC 1 chr15:102033471-10203355 ( 42) TCCTCTCC 1 chr2:170595244-170595324 ( 61) TTCCTTTC 1 chr16:88857800-88857880 ( 18) TCCTCTCC 1 chr11:65601036-65601116 ( 4) TCCCCTTC 1 chr1:182992134-182992214 ( 60) TTCCCTCC 1 chr21:47580943-47581023 ( 37) TTCCCTCC 1 chr6:49483526-49483606 ( 69) TTCTTTTC 1 chr5:34698048-34698128 ( 70) TTCTTTTC 1 chr2:230786721-230786801 ( 39) TCCCTCCC 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCCCYTCC MEME-4 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 11.1193 E= 1.2e-004 -1169 -1169 -1169 247 -1169 136 -1169 1 -1169 165 -1169 -1169 -1169 125 -1169 42 -1169 6 -1169 188 -1169 -339 -1169 242 -1169 136 -1169 1 -1169 165 -1169 -1169 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCCCYTCC MEME-4 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 33 E= 1.2e-004 0.000000 0.000000 0.000000 1.000000 0.000000 0.818182 0.000000 0.181818 0.000000 1.000000 0.000000 0.000000 0.000000 0.757576 0.000000 0.242424 0.000000 0.333333 0.000000 0.666667 0.000000 0.030303 0.000000 0.969697 0.000000 0.818182 0.000000 0.181818 0.000000 1.000000 0.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCCCYTCC MEME-4 regular expression -------------------------------------------------------------------------------- TCC[CT][TC]TCC -------------------------------------------------------------------------------- Time 16.62 secs. ******************************************************************************** ******************************************************************************** MOTIF GGGGAGGG MEME-5 width = 8 sites = 76 llr = 543 E-value = 5.0e-008 ******************************************************************************** -------------------------------------------------------------------------------- Motif GGGGAGGG MEME-5 Description -------------------------------------------------------------------------------- Simplified A 2:3:831: pos.-specific C 1:::2::: probability G 7a7a:79a matrix T :::::::: bits 2.5 2.2 2.0 1.7 * * * Relative 1.5 * ** * Entropy 1.2 * ** ** (10.3 bits) 1.0 ******* 0.7 ******** 0.5 ******** 0.2 ******** 0.0 -------- Multilevel GGGGAGGG consensus A A CA sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GGGGAGGG MEME-5 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr2:73511546-73511626 38 6.08e-05 GCAAGGGAAG GGGGAGGG AGGCAGCACC chr3:42696368-42696448 2 6.08e-05 T GGGGAGGG GGTTAAATTC chr1:167906259-167906339 36 6.08e-05 GCCTAGAGTG GGGGAGGG GGCACGCTGC chr10:43892359-43892439 2 6.08e-05 a ggggaggg gGCCCCTGGC chr19:42784897-42784977 17 6.08e-05 TCGTGAGCGC GGGGAGGG GAGGGGAACG chr6:44010163-44010243 2 6.08e-05 a ggggaggg aaggAAGACA chr19:40669135-40669215 8 6.08e-05 gggggag ggggaggg gggagggggg chr1:2332594-2332674 29 6.08e-05 GTTGTGGCCT GGGGAGGG CAGGCCCTCT chr6:20402514-20402594 4 6.08e-05 GGT GGGGAGGG GGCGGCTGTC chr19:798174-798254 58 6.08e-05 GCGCCGTCAT GGGGAGGG GCCTTCCCGG chr19:55646213-55646293 1 6.08e-05 . ggggaggg gagaggGGAA chr9:132359507-132359587 62 6.08e-05 CTTGGGCCCT GGGGAGGG CGTCAGGCGG chr12:48744834-48744914 66 6.08e-05 CCGCCGCTGT GGGGAGGG TGCGGCC chr1:28586543-28586623 1 6.08e-05 . GGGGAGGG AAAGCCGAGC chr19:1827053-1827133 2 6.08e-05 g ggggaggg gggcggggag chr1:32273032-32273112 2 6.08e-05 a ggggaggg aagggacttt chr17:7155029-7155109 37 6.08e-05 TCGCAGGAAC GGGGAGGG CGGGGGCAGC chr7:550427-550507 1 6.08e-05 . ggggaggg gagggCTCAC chr1:232861190-232861270 6 6.08e-05 gggga ggggaggg AGCCTTGTCA chr1:25056852-25056932 11 6.08e-05 gggaggggag ggggaggg gaCTCCTTCT chr6:53171164-53171244 8 9.54e-05 gggagag ggagaggg gagagagaga chr7:6543340-6543420 64 9.54e-05 GCAGAGGCGG GGAGAGGG CGGACACGG chr12:114450688-11445076 26 9.54e-05 gaaggaggag ggagaggg agagggaggt chr1:7765242-7765322 59 1.64e-04 GAGGGGCTGC AGGGAGGG GTGCGTTTGG chr14:88237680-88237760 52 1.64e-04 GGTGGGGTGG GGGGAAGG ATGGAGGCCC chr10:70092089-70092169 52 1.64e-04 CTCCCACTTC AGGGAGGG CGGCTTGCCG chr5:176924076-176924156 57 1.64e-04 TGCTGAAGAA GGGGAAGG CGGGAGTGGG chr1:12655578-12655658 64 1.64e-04 GGGAGCAGAT AGGGAGGG CTTTGCGGG chr1:221873484-221873564 47 1.64e-04 ggaagggaag agggaggg aaggaaagag chr17:44202476-44202556 5 1.64e-04 aggg agggaggg aaagaaattg chr20:29647715-29647795 47 1.64e-04 ggaaggaggg agggaggg aaggaaggaa chr19:13265766-13265846 72 2.04e-04 CACGTGGGCG AGAGAGGG T chr19:42637388-42637468 58 2.04e-04 GGCCGGCTGC GGAGAAGG GAGCCCCTCC chr1:87794614-87794694 46 2.04e-04 AGTCGGAGGC GGAGAAGG ACGAAGACTG chr1:1179981-1180061 7 2.04e-04 CGGCCA GGAGAAGG ACCCACGGCC chr10:70262768-70262848 5 2.04e-04 gaaa ggagaAGG AAAGAAATTG chr9:136223681-136223761 27 2.23e-04 aggggaggag agggaagg ggGCGCGGCA chr10:73958149-73958229 9 2.23e-04 ggaaggga agggaagg aaggaaagaa chr5:68264382-68264462 7 2.23e-04 aaggga agggaagg gGcaaacatg chr7:128341517-128341597 5 2.23e-04 ggga agggaagg gggtcttatt chr13:23500586-23500666 65 2.23e-04 GGAGCTGCGG AGGGAAGG GGAGGAGC chr4:174089929-174090009 1 2.69e-04 . ggggagag cggtggcggc chr2:172017000-172017080 60 2.69e-04 agggctggga ggggagag tcaaggggat chr12:121268392-12126847 37 2.69e-04 TGCATATGTT GGGGAGAG CAAGGGTGGT chr5:171881142-171881222 18 2.69e-04 gcagagccga ggggagag caggggagga chr7:128046207-128046287 50 2.69e-04 TGGGGCTGCG GGGGAGAG TACCGGGTCA chr5:15411132-15411212 42 2.88e-04 CCTTGTAATA GGAGAGAG AATGCCAAAC chr13:50366782-50366862 49 4.35e-04 CGGGCCGGGT GGGGCGGG AACGGTGCTG chr10:65389964-65390044 44 4.35e-04 AAGAACGCCA GGGGCGGG GCGACCGCGG chr1:16494444-16494524 40 4.35e-04 CATGGAAACC GGGGCGGG GAGGCGGCGG chr10:63491548-63491628 8 4.35e-04 ggaaggg ggggaAAG TTTCTTTTTT chr6:44095185-44095265 47 4.35e-04 GCCGGCGTGC GGGGCGGG ACCTGCGGGG chr9:95821064-95821144 5 4.35e-04 cccg ggggcggg ccggggTCAC chr22:21311813-21311893 73 4.35e-04 GACCTTGCGC GGGGCGGG chr4:1769012-1769092 57 4.35e-04 GCAGCCTGAG GGGGCGGG Tctcccctcc chr11:77185060-77185140 39 4.96e-04 GCTGCAGCCG CGGGAGGG CAGCCTCCCC chr15:75940067-75940147 24 4.96e-04 CCCGGGCCCG CGGGAGGG CGGAGCTGGC chr17:80606749-80606829 28 4.96e-04 AGCACGTTCG CGGGAGGG TCTGGCCTTG chr8:142085752-142085832 52 4.96e-04 CTAGTTACTG CGGGAGGG GCTCCAAGGC chr10:23384502-23384582 24 5.79e-04 gagcggcgcc ggagcggg CGTCATGGCG chr15:38544419-38544499 61 5.79e-04 GGCGGCGGAA GGAGCGGG CGGCGTGAGC chr19:3367328-3367408 61 5.79e-04 GCCGCCGGGA GGAGCGGG AGGCCCGGCG chr8:98748669-98748749 10 5.79e-04 aaggagAAA GGAGAAAG GAGAAACCTT chr1:182992134-182992214 37 5.79e-04 TCCCGCGCGG GGAGCGGG TCTGCGAGGC chr15:90545207-90545287 7 5.79e-04 agagag agagagag agagagagGC chr12:57916707-57916787 58 7.12e-04 GCGACTGCGC AGGGCGGG GCCGGCCGAA chr9:86237993-86238073 71 7.81e-04 cggAAGGCGA CGGGAAGG AG chr7:26241556-26241636 17 7.81e-04 CCGGGAGCTG CGGGAAGG AGTGGAGGGT chr8:142425896-142425976 70 7.81e-04 TGGAGGACTC CGGGAAGG CGT chr12:53297391-53297471 61 8.56e-04 CCGCTGGGGC GGAGCAGG GACAGGACGC chr10:60095101-60095181 58 8.56e-04 AGGTGAGGTG GGAGCAGG GTCAGGTCCC chr1:6453759-6453839 18 8.56e-04 CCTAAGTGGC GGAGCAGG GCGGACTTGG chr2:55711202-55711282 3 8.56e-04 AG AGAGAAAG AGTGGGAATA chr1:895958-896038 21 8.56e-04 TGAGCGACAC AGAGCGGG CCGCCACCGC chr1:160370211-160370291 2 8.56e-04 A AGAGCGGG GCCGCAGACA chr6:74230216-74230296 21 9.30e-04 GCCAGGCACC AGAGCAGG CCGGCCAGCT -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GGGGAGGG MEME-5 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr2:73511546-73511626 6.1e-05 37_[+5]_35 chr3:42696368-42696448 6.1e-05 1_[+5]_71 chr1:167906259-167906339 6.1e-05 35_[+5]_37 chr10:43892359-43892439 6.1e-05 1_[+5]_71 chr19:42784897-42784977 6.1e-05 16_[+5]_56 chr6:44010163-44010243 6.1e-05 1_[+5]_71 chr19:40669135-40669215 6.1e-05 7_[+5]_65 chr1:2332594-2332674 6.1e-05 28_[+5]_44 chr6:20402514-20402594 6.1e-05 3_[+5]_69 chr19:798174-798254 6.1e-05 57_[+5]_15 chr19:55646213-55646293 6.1e-05 [+5]_72 chr9:132359507-132359587 6.1e-05 61_[+5]_11 chr12:48744834-48744914 6.1e-05 65_[+5]_7 chr1:28586543-28586623 6.1e-05 [+5]_72 chr19:1827053-1827133 6.1e-05 1_[+5]_71 chr1:32273032-32273112 6.1e-05 1_[+5]_71 chr17:7155029-7155109 6.1e-05 36_[+5]_36 chr7:550427-550507 6.1e-05 [+5]_72 chr1:232861190-232861270 6.1e-05 5_[+5]_67 chr1:25056852-25056932 6.1e-05 10_[+5]_62 chr6:53171164-53171244 9.5e-05 7_[+5]_65 chr7:6543340-6543420 9.5e-05 63_[+5]_9 chr12:114450688-11445076 9.5e-05 25_[+5]_47 chr1:7765242-7765322 0.00016 58_[+5]_14 chr14:88237680-88237760 0.00016 51_[+5]_21 chr10:70092089-70092169 0.00016 51_[+5]_21 chr5:176924076-176924156 0.00016 56_[+5]_16 chr1:12655578-12655658 0.00016 63_[+5]_9 chr1:221873484-221873564 0.00016 46_[+5]_26 chr17:44202476-44202556 0.00016 4_[+5]_68 chr20:29647715-29647795 0.00016 46_[+5]_26 chr19:13265766-13265846 0.0002 71_[+5]_1 chr19:42637388-42637468 0.0002 57_[+5]_15 chr1:87794614-87794694 0.0002 45_[+5]_27 chr1:1179981-1180061 0.0002 6_[+5]_66 chr10:70262768-70262848 0.0002 4_[+5]_68 chr9:136223681-136223761 0.00022 26_[+5]_46 chr10:73958149-73958229 0.00022 8_[+5]_64 chr5:68264382-68264462 0.00022 6_[+5]_66 chr7:128341517-128341597 0.00022 4_[+5]_68 chr13:23500586-23500666 0.00022 64_[+5]_8 chr4:174089929-174090009 0.00027 [+5]_72 chr2:172017000-172017080 0.00027 59_[+5]_13 chr12:121268392-12126847 0.00027 36_[+5]_36 chr5:171881142-171881222 0.00027 17_[+5]_55 chr7:128046207-128046287 0.00027 49_[+5]_23 chr5:15411132-15411212 0.00029 41_[+5]_31 chr13:50366782-50366862 0.00043 48_[+5]_24 chr10:65389964-65390044 0.00043 43_[+5]_29 chr1:16494444-16494524 0.00043 39_[+5]_33 chr10:63491548-63491628 0.00043 7_[+5]_65 chr6:44095185-44095265 0.00043 46_[+5]_26 chr9:95821064-95821144 0.00043 4_[+5]_68 chr22:21311813-21311893 0.00043 72_[+5] chr4:1769012-1769092 0.00043 56_[+5]_16 chr11:77185060-77185140 0.0005 38_[+5]_34 chr15:75940067-75940147 0.0005 23_[+5]_49 chr17:80606749-80606829 0.0005 27_[+5]_45 chr8:142085752-142085832 0.0005 51_[+5]_21 chr10:23384502-23384582 0.00058 23_[+5]_49 chr15:38544419-38544499 0.00058 60_[+5]_12 chr19:3367328-3367408 0.00058 60_[+5]_12 chr8:98748669-98748749 0.00058 9_[+5]_63 chr1:182992134-182992214 0.00058 36_[+5]_36 chr15:90545207-90545287 0.00058 6_[+5]_66 chr12:57916707-57916787 0.00071 57_[+5]_15 chr9:86237993-86238073 0.00078 70_[+5]_2 chr7:26241556-26241636 0.00078 16_[+5]_56 chr8:142425896-142425976 0.00078 69_[+5]_3 chr12:53297391-53297471 0.00086 60_[+5]_12 chr10:60095101-60095181 0.00086 57_[+5]_15 chr1:6453759-6453839 0.00086 17_[+5]_55 chr2:55711202-55711282 0.00086 2_[+5]_70 chr1:895958-896038 0.00086 20_[+5]_52 chr1:160370211-160370291 0.00086 1_[+5]_71 chr6:74230216-74230296 0.00093 20_[+5]_52 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GGGGAGGG MEME-5 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF GGGGAGGG width=8 seqs=76 chr2:73511546-73511626 ( 38) GGGGAGGG 1 chr3:42696368-42696448 ( 2) GGGGAGGG 1 chr1:167906259-167906339 ( 36) GGGGAGGG 1 chr10:43892359-43892439 ( 2) GGGGAGGG 1 chr19:42784897-42784977 ( 17) GGGGAGGG 1 chr6:44010163-44010243 ( 2) GGGGAGGG 1 chr19:40669135-40669215 ( 8) GGGGAGGG 1 chr1:2332594-2332674 ( 29) GGGGAGGG 1 chr6:20402514-20402594 ( 4) GGGGAGGG 1 chr19:798174-798254 ( 58) GGGGAGGG 1 chr19:55646213-55646293 ( 1) GGGGAGGG 1 chr9:132359507-132359587 ( 62) GGGGAGGG 1 chr12:48744834-48744914 ( 66) GGGGAGGG 1 chr1:28586543-28586623 ( 1) GGGGAGGG 1 chr19:1827053-1827133 ( 2) GGGGAGGG 1 chr1:32273032-32273112 ( 2) GGGGAGGG 1 chr17:7155029-7155109 ( 37) GGGGAGGG 1 chr7:550427-550507 ( 1) GGGGAGGG 1 chr1:232861190-232861270 ( 6) GGGGAGGG 1 chr1:25056852-25056932 ( 11) GGGGAGGG 1 chr6:53171164-53171244 ( 8) GGAGAGGG 1 chr7:6543340-6543420 ( 64) GGAGAGGG 1 chr12:114450688-11445076 ( 26) GGAGAGGG 1 chr1:7765242-7765322 ( 59) AGGGAGGG 1 chr14:88237680-88237760 ( 52) GGGGAAGG 1 chr10:70092089-70092169 ( 52) AGGGAGGG 1 chr5:176924076-176924156 ( 57) GGGGAAGG 1 chr1:12655578-12655658 ( 64) AGGGAGGG 1 chr1:221873484-221873564 ( 47) AGGGAGGG 1 chr17:44202476-44202556 ( 5) AGGGAGGG 1 chr20:29647715-29647795 ( 47) AGGGAGGG 1 chr19:13265766-13265846 ( 72) AGAGAGGG 1 chr19:42637388-42637468 ( 58) GGAGAAGG 1 chr1:87794614-87794694 ( 46) GGAGAAGG 1 chr1:1179981-1180061 ( 7) GGAGAAGG 1 chr10:70262768-70262848 ( 5) GGAGAAGG 1 chr9:136223681-136223761 ( 27) AGGGAAGG 1 chr10:73958149-73958229 ( 9) AGGGAAGG 1 chr5:68264382-68264462 ( 7) AGGGAAGG 1 chr7:128341517-128341597 ( 5) AGGGAAGG 1 chr13:23500586-23500666 ( 65) AGGGAAGG 1 chr4:174089929-174090009 ( 1) GGGGAGAG 1 chr2:172017000-172017080 ( 60) GGGGAGAG 1 chr12:121268392-12126847 ( 37) GGGGAGAG 1 chr5:171881142-171881222 ( 18) GGGGAGAG 1 chr7:128046207-128046287 ( 50) GGGGAGAG 1 chr5:15411132-15411212 ( 42) GGAGAGAG 1 chr13:50366782-50366862 ( 49) GGGGCGGG 1 chr10:65389964-65390044 ( 44) GGGGCGGG 1 chr1:16494444-16494524 ( 40) GGGGCGGG 1 chr10:63491548-63491628 ( 8) GGGGAAAG 1 chr6:44095185-44095265 ( 47) GGGGCGGG 1 chr9:95821064-95821144 ( 5) GGGGCGGG 1 chr22:21311813-21311893 ( 73) GGGGCGGG 1 chr4:1769012-1769092 ( 57) GGGGCGGG 1 chr11:77185060-77185140 ( 39) CGGGAGGG 1 chr15:75940067-75940147 ( 24) CGGGAGGG 1 chr17:80606749-80606829 ( 28) CGGGAGGG 1 chr8:142085752-142085832 ( 52) CGGGAGGG 1 chr10:23384502-23384582 ( 24) GGAGCGGG 1 chr15:38544419-38544499 ( 61) GGAGCGGG 1 chr19:3367328-3367408 ( 61) GGAGCGGG 1 chr8:98748669-98748749 ( 10) GGAGAAAG 1 chr1:182992134-182992214 ( 37) GGAGCGGG 1 chr15:90545207-90545287 ( 7) AGAGAGAG 1 chr12:57916707-57916787 ( 58) AGGGCGGG 1 chr9:86237993-86238073 ( 71) CGGGAAGG 1 chr7:26241556-26241636 ( 17) CGGGAAGG 1 chr8:142425896-142425976 ( 70) CGGGAAGG 1 chr12:53297391-53297471 ( 61) GGAGCAGG 1 chr10:60095101-60095181 ( 58) GGAGCAGG 1 chr1:6453759-6453839 ( 18) GGAGCAGG 1 chr2:55711202-55711282 ( 3) AGAGAAAG 1 chr1:895958-896038 ( 21) AGAGCGGG 1 chr1:160370211-160370291 ( 2) AGAGCGGG 1 chr6:74230216-74230296 ( 21) AGAGCAGG 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GGGGAGGG MEME-5 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 9.34604 E= 5.0e-008 39 -179 107 -1289 -1289 -1289 165 -1289 68 -1289 115 -1289 -1289 -1289 165 -1289 208 -43 -1289 -1289 61 -1289 118 -1289 -46 -1289 144 -1289 -1289 -1289 165 -1289 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GGGGAGGG MEME-5 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 76 E= 5.0e-008 0.236842 0.092105 0.671053 0.000000 0.000000 0.000000 1.000000 0.000000 0.289474 0.000000 0.710526 0.000000 0.000000 0.000000 1.000000 0.000000 0.763158 0.236842 0.000000 0.000000 0.276316 0.000000 0.723684 0.000000 0.131579 0.000000 0.868421 0.000000 0.000000 0.000000 1.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GGGGAGGG MEME-5 regular expression -------------------------------------------------------------------------------- [GA]G[GA]G[AC][GA]GG -------------------------------------------------------------------------------- Time 20.30 secs. ******************************************************************************** ******************************************************************************** SUMMARY OF MOTIFS ******************************************************************************** -------------------------------------------------------------------------------- Combined block diagrams: non-overlapping sites with p-value < 0.0001 -------------------------------------------------------------------------------- SEQUENCE NAME COMBINED P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr21:47580943-47581023 3.14e-01 80 chr16:88857800-88857880 3.16e-01 80 chr8:22456439-22456519 9.99e-01 80 chr8:142085752-142085832 5.76e-01 80 chr4:726015-726095 2.10e-01 21_[+4(8.75e-05)]_51 chrX:153665440-153665520 9.32e-01 80 chr15:90545207-90545287 1.10e-02 31_[+1(5.85e-05)]_41 chr5:180527779-180527859 1.36e-01 71_[+4(8.75e-05)]_1 chr17:75352636-75352716 1.44e-01 80 chr10:89623291-89623371 5.67e-01 80 chr10:70262768-70262848 1.20e-06 12_[+1(7.24e-06)]_60 chr1:182992134-182992214 1.19e-01 80 chr8:98748669-98748749 5.79e-02 80 chr10:35104320-35104400 9.55e-01 80 chr2:3738086-3738166 7.91e-03 24_[+2(2.40e-05)]_3_[+2(3.15e-05)]_\ 37 chr4:1769012-1769092 7.03e-02 66_[+4(8.75e-05)]_6 chr1:1052359-1052439 5.83e-01 80 chr7:1546072-1546152 5.19e-01 80 chr7:130895530-130895610 5.87e-02 80 chr2:170595244-170595324 3.70e-04 80 chr9:140306231-140306311 6.45e-01 80 chr20:29647715-29647795 3.86e-01 80 chr8:144635221-144635301 9.74e-01 80 chr13:50571159-50571239 9.11e-01 80 chr2:26699270-26699350 6.99e-01 80 chr1:1363630-1363710 8.78e-01 80 chr7:128046207-128046287 6.15e-01 80 chr5:130614326-130614406 9.98e-08 16_[+3(3.38e-05)]_3_[+2(1.53e-05)]_\ 3_[+1(1.07e-05)]_18_[+4(3.07e-05)]_8 chr17:44202476-44202556 1.19e-05 12_[+1(7.24e-06)]_60 chr2:3737792-3737872 1.87e-02 37_[+4(8.75e-05)]_3_[+4(1.96e-05)]_\ 13_[+4(8.75e-05)]_3 chr5:176559876-176559956 9.98e-01 80 chr1:32083861-32083941 2.30e-02 80 chr11:34006997-34007077 8.92e-07 32_[+2(5.49e-06)]_17_[+1(2.03e-06)]_\ 15 chr9:140410082-140410162 9.73e-01 80 chr9:37286676-37286756 5.19e-03 80 chr1:25056852-25056932 6.11e-07 4_[+5(6.08e-05)]_27_[+3(6.73e-05)]_\ 20_[+3(1.30e-05)]_5 chr6:159364585-159364665 1.00e-03 7_[+2(6.96e-05)]_3_[+3(6.09e-05)]_\ 54 chr1:232861190-232861270 4.07e-02 [+5(6.08e-05)]_72 chr16:23993262-23993342 2.51e-02 4_[+4(1.96e-05)]_9_[+4(1.96e-05)]_3_\ [+4(1.96e-05)]_3_[+4(1.96e-05)]_3_[+4(1.96e-05)]_10_[+4(1.96e-05)] chr7:550427-550507 1.45e-01 [+5(6.08e-05)]_72 chr6:24238433-24238513 9.84e-02 80 chr12:114450688-11445076 1.03e-01 25_[+5(9.54e-05)]_47 chr17:7155029-7155109 3.45e-01 36_[+5(6.08e-05)]_36 chr1:235575337-235575417 2.20e-03 72_[+4(1.96e-05)] chr5:96272069-96272149 9.17e-01 80 chr1:32273032-32273112 1.32e-08 1_[+5(6.08e-05)]_7_[+2(1.21e-05)]_\ 12_[+1(2.03e-06)]_5_[+1(1.71e-05)]_3_[+3(9.82e-06)]_12 chr4:94369979-94370059 2.10e-01 4_[+4(1.96e-05)]_2_[+4(1.96e-05)]_2_\ [+4(1.96e-05)]_3_[+4(1.96e-05)]_3_[+4(1.96e-05)]_3_[+4(1.96e-05)]_15 chr9:139591195-139591275 3.41e-03 59_[+2(5.01e-05)]_13 chr21:38411957-38412037 1.37e-01 34_[+4(1.96e-05)]_23_[+4(1.96e-05)]_\ 7 chr19:35759842-35759922 3.42e-01 34_[+4(8.75e-05)]_38 chr1:241838429-241838509 2.15e-01 17_[+4(5.29e-05)]_31_[+4(5.29e-05)]_\ 16 chr1:27320085-27320165 3.06e-02 80 chr4:175145847-175145927 3.14e-02 42_[+2(6.64e-06)]_30 chr22:19746138-19746218 8.00e-01 80 chr1:1179981-1180061 5.15e-01 80 chr16:447754-447834 9.27e-01 80 chr5:1667318-1667398 3.14e-01 80 chr5:108676228-108676308 4.99e-06 35_[+1(3.18e-06)]_11_[+2(3.70e-05)]_\ 18 chr9:132372533-132372613 8.13e-01 80 chr15:102033471-10203355 7.82e-04 15_[+1(8.68e-05)]_57 chr19:39005868-39005948 9.41e-01 80 chr6:34941753-34941833 1.07e-01 45_[+4(1.96e-05)]_27 chr1:156716935-156717015 5.28e-01 80 chr14:102227447-10222752 9.59e-01 80 chr7:151574771-151574851 4.85e-01 80 chr11:4637239-4637319 3.96e-05 62_[+4(1.96e-05)]_10 chr1:27929568-27929648 7.36e-01 80 chr19:1827053-1827133 3.13e-01 1_[+5(6.08e-05)]_71 chr1:221873484-221873564 4.76e-03 14_[+5(9.54e-05)]_8_[+5(9.54e-05)]_\ 32_[+1(3.45e-05)]_2 chr4:1750626-1750706 8.36e-01 80 chr8:74790690-74790770 9.81e-01 80 chr7:152190728-152190808 2.46e-03 80 chr17:28257197-28257277 8.75e-01 80 chr19:1123159-1123239 9.21e-01 80 chr5:34698048-34698128 1.08e-02 80 chr2:174877694-174877774 1.37e-01 80 chr22:21311813-21311893 7.08e-01 80 chr13:23500586-23500666 4.52e-01 80 chr7:150342888-150342968 1.47e-02 55_[+4(5.29e-05)]_17 chr7:6543340-6543420 4.37e-01 41_[+5(9.54e-05)]_14_[+5(9.54e-05)]_\ 9 chr1:28586543-28586623 7.44e-02 [+5(6.08e-05)]_72 chr6:33378572-33378652 2.14e-01 80 chr7:128341517-128341597 5.94e-02 80 chr10:32144088-32144168 4.39e-02 80 chr17:5185440-5185520 9.63e-01 80 chr19:3367328-3367408 2.62e-01 80 chr8:68252035-68252115 2.32e-05 13_[+2(1.21e-05)]_32_[+3(6.09e-05)]_\ 19 chr1:12655578-12655658 4.56e-01 80 chr9:95821064-95821144 7.00e-01 80 chr20:33292011-33292091 8.23e-01 80 chr17:80606749-80606829 4.02e-01 80 chr10:80826892-80826972 9.71e-01 80 chr15:38544419-38544499 1.08e-01 80 chr15:79603361-79603441 9.55e-01 80 chr19:1161950-1162030 9.66e-01 80 chr2:61698182-61698262 3.23e-02 17_[+2(2.40e-05)]_55 chr5:68264382-68264462 1.89e-03 80 chr6:44095185-44095265 3.12e-01 80 chr5:176924076-176924156 4.45e-01 80 chr9:139943096-139943176 9.55e-01 80 chr5:171881142-171881222 2.39e-02 80 chr1:87794614-87794694 2.66e-01 80 chr1:160370211-160370291 3.50e-01 80 chr5:42978705-42978785 1.04e-05 25_[+2(5.13e-05)]_6_[+2(1.85e-05)]_\ 5_[+1(6.73e-05)]_20 chr16:78638472-78638552 9.12e-05 57_[+2(3.15e-05)]_3_[+2(2.40e-05)]_\ 4 chr19:3046839-3046919 3.24e-01 80 chr17:46089707-46089787 9.99e-01 80 chr8:28259957-28260037 9.30e-01 80 chr6:50603335-50603415 7.02e-04 34_[+3(9.82e-06)]_20_[+1(9.92e-05)]_\ 10 chr12:48744834-48744914 2.15e-01 65_[+5(6.08e-05)]_7 chr1:42687793-42687873 4.54e-02 6_[+3(7.31e-05)]_66 chr8:130491160-130491240 9.33e-04 58_[+3(7.92e-05)]_5_[+1(5.06e-05)]_\ 1 chr12:57916707-57916787 4.69e-01 80 chr12:121268392-12126847 4.54e-02 80 chr3:185083562-185083642 3.68e-05 10_[+1(5.49e-05)]_8_[+3(9.55e-05)]_\ 15_[+4(1.96e-05)]_23 chr8:142425896-142425976 8.00e-01 80 chr7:128341273-128341353 1.59e-05 9_[+1(9.92e-05)]_16_[+3(1.62e-05)]_\ 15_[+2(6.00e-05)]_16 chr6:79787980-79788060 3.63e-01 80 chr22:20767577-20767657 2.61e-05 2_[+1(2.03e-06)]_[+1(2.03e-06)]_2_\ [+1(2.03e-06)]_52 chr9:132359507-132359587 8.21e-02 61_[+5(6.08e-05)]_11 chr17:56408770-56408850 9.88e-01 80 chr12:132579249-13257932 2.50e-01 80 chr16:89313546-89313626 9.24e-01 80 chr21:47843802-47843882 6.98e-03 42_[+2(6.96e-05)]_30 chr9:136223449-136223529 9.98e-01 80 chr15:75940067-75940147 2.45e-01 80 chr11:2913886-2913966 8.26e-01 80 chr13:50570882-50570962 6.84e-01 80 chr1:90098716-90098796 9.80e-01 80 chr1:204463858-204463938 9.99e-01 80 chr2:174829109-174829189 9.67e-01 80 chr19:55646213-55646293 6.95e-05 [+5(6.08e-05)]_8_[+1(2.03e-06)]_5_\ [+1(2.03e-06)]_43 chr19:798174-798254 1.68e-01 57_[+5(6.08e-05)]_15 chr5:34698255-34698335 2.15e-01 1_[+4(1.96e-05)]_4_[+4(8.75e-05)]_\ [+4(1.96e-05)]_5_[+4(1.96e-05)]_10_[+4(1.96e-05)]_11_[+4(8.75e-05)]_1 chr10:73958149-73958229 4.83e-04 20_[+1(2.03e-06)]_52 chr19:42637388-42637468 1.45e-01 80 chr18:74534792-74534872 5.45e-02 80 chr6:44214187-44214267 1.96e-01 80 chr17:78564878-78564958 3.71e-02 80 chr6:20402514-20402594 5.43e-02 3_[+5(6.08e-05)]_69 chr7:158424609-158424689 1.94e-01 80 chr10:63491548-63491628 7.79e-08 20_[+2(6.64e-06)]_26_[+1(9.55e-06)]_\ 6_[+3(2.29e-05)]_4 chr10:81204733-81204813 9.12e-01 80 chr1:2332594-2332674 4.85e-03 28_[+5(6.08e-05)]_34_[+4(1.96e-05)]_\ 2 chr7:26241556-26241636 7.88e-01 80 chr6:165038109-165038189 1.03e-06 5_[+1(1.27e-05)]_4_[+3(4.37e-05)]_\ 45_[+4(3.07e-05)]_2 chr16:8962331-8962411 9.60e-01 80 chr18:45456851-45456931 1.85e-01 80 chr19:40669135-40669215 1.46e-01 1_[+5(6.08e-05)]_5_[+5(6.08e-05)]_\ 58 chr20:62104414-62104494 9.70e-01 80 chr19:955141-955221 8.02e-01 80 chr18:29616631-29616711 1.35e-05 7_[+3(4.37e-05)]_55_[+2(1.85e-05)]_\ 2 chr2:172017000-172017080 4.11e-01 80 chr17:20945898-20945978 7.92e-01 80 chr7:77396247-77396327 4.77e-06 7_[+3(6.73e-05)]_24_[+2(5.49e-06)]_\ 25_[+4(3.07e-05)] chr2:230786721-230786801 5.07e-01 80 chr4:174089929-174090009 2.29e-01 80 chr8:143858776-143858856 1.00e+00 80 chr6:44010163-44010243 7.03e-04 1_[+5(6.08e-05)]_27_[+2(6.00e-05)]_\ 36 chr19:3577007-3577087 9.97e-01 80 chr9:136223681-136223761 3.42e-01 22_[+5(9.54e-05)]_50 chr5:137803113-137803193 8.98e-01 80 chr10:23384502-23384582 7.12e-01 80 chr1:9600007-9600087 4.18e-01 80 chr8:19675154-19675234 2.87e-01 80 chr1:895958-896038 7.80e-01 80 chr5:15411132-15411212 1.28e-05 66_[+4(5.29e-05)]_6 chr5:44779421-44779501 6.50e-06 14_[+3(1.15e-06)]_58 chr6:151712009-151712089 9.98e-01 80 chr1:21713382-21713462 1.14e-02 19_[+1(2.34e-05)]_53 chr11:77489345-77489425 2.34e-05 7_[+1(6.32e-05)]_19_[+2(6.00e-05)]_\ 29_[+3(7.52e-06)]_1 chr6:166815843-166815923 1.82e-02 3_[+1(8.68e-05)]_69 chr4:94370181-94370261 7.77e-05 68_[+1(3.45e-05)]_4 chr19:42784897-42784977 6.55e-02 16_[+5(6.08e-05)]_56 chr11:65192506-65192586 5.54e-04 56_[+3(1.19e-05)]_16 chr17:73775382-73775462 4.95e-01 80 chr10:70092089-70092169 2.69e-01 80 chr11:65601036-65601116 4.39e-01 80 chr22:20786080-20786160 4.59e-01 80 chr1:153895165-153895245 5.42e-01 80 chr6:155054899-155054979 9.60e-01 80 chr7:128864874-128864954 9.35e-01 80 chr2:163605220-163605300 4.04e-02 80 chr1:16494444-16494524 1.02e-01 80 chr19:13265766-13265846 4.51e-01 80 chr16:46612217-46612297 1.15e-05 13_[+1(2.03e-06)]_24_[+2(3.47e-05)]_\ 27 chr11:77185060-77185140 3.48e-01 80 chr2:55711202-55711282 4.75e-03 56_[+4(1.96e-05)]_2_[+4(1.96e-05)]_\ 6 chr10:65389964-65390044 3.63e-01 80 chr5:44888712-44888792 1.69e-06 4_[+1(7.24e-06)]_2_[+3(6.73e-05)]_\ 41_[+2(7.79e-06)]_9 chr1:6453759-6453839 2.17e-02 80 chr7:138087653-138087733 5.73e-05 8_[+1(2.03e-06)]_39_[+1(3.18e-06)]_\ 17 chr3:130355483-130355563 4.12e-03 31_[+3(6.09e-05)]_41 chr8:79100825-79100905 4.94e-06 1_[+3(3.38e-05)]_34_[+3(1.42e-05)]_\ 8_[+3(5.49e-06)]_1_[+1(3.18e-06)]_4 chr1:167599521-167599601 8.72e-01 80 chr4:151579571-151579651 3.58e-02 10_[+2(9.10e-05)]_62 chr14:77413749-77413829 9.88e-01 80 chr7:23510784-23510864 9.63e-01 80 chr1:203765039-203765119 4.79e-01 80 chr1:180992052-180992132 8.90e-01 80 chr22:20226790-20226870 8.61e-01 80 chr1:2477805-2477885 8.32e-01 80 chr3:20081530-20081610 1.00e+00 80 chr7:75831069-75831149 7.17e-01 80 chr12:46384141-46384221 9.95e-01 80 chr12:50987399-50987479 1.23e-01 80 chr10:43892359-43892439 3.68e-01 1_[+5(6.08e-05)]_71 chrX:122994040-122994120 6.03e-01 80 chr3:38495246-38495326 7.99e-02 71_[+4(8.75e-05)]_1 chr8:4032310-4032390 2.80e-04 38_[+3(3.18e-06)]_22_[+3(9.82e-06)]_\ 4 chr10:13142153-13142233 7.84e-01 80 chr1:3816796-3816876 9.97e-01 80 chr22:38901870-38901950 2.59e-01 80 chr16:22385330-22385410 1.86e-01 80 chr15:72523637-72523717 5.94e-01 80 chr19:1856969-1857049 9.92e-01 80 chr17:45727795-45727875 7.61e-01 80 chr22:20778676-20778756 3.09e-02 80 chr6:32143651-32143731 9.58e-01 80 chr3:140661054-140661134 8.20e-01 80 chr19:4328504-4328584 9.65e-01 80 chr6:74230216-74230296 6.31e-01 80 chr3:50654554-50654634 8.20e-01 80 chr1:167906259-167906339 3.17e-01 35_[+5(6.08e-05)]_37 chr1:30558908-30558988 9.60e-01 80 chr17:42297484-42297564 8.82e-01 80 chr14:88237680-88237760 2.63e-02 80 chr10:75634135-75634215 7.17e-01 80 chr15:75165681-75165761 4.55e-01 80 chr3:42696368-42696448 1.84e-02 1_[+5(6.08e-05)]_71 chr6:53171164-53171244 2.44e-05 1_[+5(9.54e-05)]_18_[+5(9.54e-05)]_\ 27_[+1(7.76e-05)]_10 chr4:6784301-6784381 5.77e-02 80 chr2:73511546-73511626 9.23e-02 37_[+5(6.08e-05)]_35 chr10:60095101-60095181 8.27e-01 80 chr19:45999832-45999912 8.07e-01 80 chr9:86237993-86238073 6.10e-01 80 chr17:74137450-74137530 8.67e-01 80 chr7:105162271-105162351 7.03e-01 80 chr21:40050904-40050984 2.78e-05 43_[+2(1.15e-06)]_7_[+3(3.90e-05)]_\ 14 chr6:49483526-49483606 3.04e-05 13_[+2(2.30e-06)]_50_[+2(6.00e-05)]_\ 1 chr13:50366782-50366862 6.86e-01 80 chr11:65190871-65190951 9.98e-01 80 chr17:47755318-47755398 2.90e-01 80 chr1:53018677-53018757 9.99e-01 80 chr12:53297391-53297471 2.97e-01 80 chr2:27938557-27938637 6.05e-01 80 chr7:152409674-152409754 1.02e-04 6_[+2(3.47e-05)]_36_[+4(1.96e-05)]_\ 2_[+4(1.96e-05)]_2_[+4(1.96e-05)]_2 chr1:7765242-7765322 3.07e-01 80 chr1:6052110-6052190 9.53e-01 80 chr20:61640578-61640658 8.36e-01 80 -------------------------------------------------------------------------------- ******************************************************************************** ******************************************************************************** Stopped because requested number of motifs (5) found. ******************************************************************************** CPU: c22n09.farnam.hpc.yale.internal ********************************************************************************