******************************************************************************** MEME - Motif discovery tool ******************************************************************************** MEME version 5.3.3 (Release date: Sun Feb 7 15:39:52 2021 -0800) For further information on how to interpret these results please access https://meme-suite.org/meme. To get a copy of the MEME Suite software please access https://meme-suite.org. ******************************************************************************** ******************************************************************************** REFERENCE ******************************************************************************** If you use this program in your research, please cite: Timothy L. Bailey and Charles Elkan, "Fitting a mixture model by expectation maximization to discover motifs in biopolymers", Proceedings of the Second International Conference on Intelligent Systems for Molecular Biology, pp. 28-36, AAAI Press, Menlo Park, California, 1994. ******************************************************************************** ******************************************************************************** TRAINING SET ******************************************************************************** PRIMARY SEQUENCES= ../result/final_prediction/K562/fasta/RankLinear0.6_40/NUFIP1.fasta CONTROL SEQUENCES= --none-- ALPHABET= ACGT Sequence name Weight Length Sequence name Weight Length ------------- ------ ------ ------------- ------ ------ chr7:158317045-158317125 1.0000 80 chr9:132164077-132164157 1.0000 80 chr12:54388541-54388621 1.0000 80 chr19:14318414-14318494 1.0000 80 chr1:10739817-10739897 1.0000 80 chr17:19015575-19015655 1.0000 80 chr18:61034946-61035026 1.0000 80 chr17:19091383-19091463 1.0000 80 chr12:108999511-10899959 1.0000 80 chr2:96917555-96917635 1.0000 80 chr15:70403732-70403812 1.0000 80 chr19:12947212-12947292 1.0000 80 chrX:65383971-65384051 1.0000 80 chr1:46867979-46868059 1.0000 80 chr6:160147314-160147394 1.0000 80 chrX:152419847-152419927 1.0000 80 chr3:197071907-197071987 1.0000 80 chr17:74016050-74016130 1.0000 80 chr12:108999974-10900005 1.0000 80 chr1:17566023-17566103 1.0000 80 chr7:66395436-66395516 1.0000 80 chr9:2241973-2242053 1.0000 80 chr17:29035871-29035951 1.0000 80 chr17:44269422-44269502 1.0000 80 chr12:54682650-54682730 1.0000 80 chr8:144152496-144152576 1.0000 80 chr15:93444566-93444646 1.0000 80 chr17:36754955-36755035 1.0000 80 chr12:53297256-53297336 1.0000 80 chr7:32702205-32702285 1.0000 80 chr1:10039-10119 1.0000 80 chr5:81253972-81254052 1.0000 80 chr17:18967112-18967192 1.0000 80 chr3:197161044-197161124 1.0000 80 chr17:39656109-39656189 1.0000 80 chr1:142783033-142783113 1.0000 80 chr1:114491684-114491764 1.0000 80 chr1:28655094-28655174 1.0000 80 chr11:61348959-61349039 1.0000 80 chr6:37017304-37017384 1.0000 80 chr22:39925317-39925397 1.0000 80 chr1:27013471-27013551 1.0000 80 chr22:20115745-20115825 1.0000 80 chrX:129300133-129300213 1.0000 80 chr12:74686555-74686635 1.0000 80 chr6:26193856-26193936 1.0000 80 chr8:38008417-38008497 1.0000 80 chr1:21672981-21673061 1.0000 80 chrX:153236079-153236159 1.0000 80 chr1:249184753-249184833 1.0000 80 chr6:34244784-34244864 1.0000 80 chr3:156271870-156271950 1.0000 80 chr6:28986045-28986125 1.0000 80 chr1:179851218-179851298 1.0000 80 chr17:38225323-38225403 1.0000 80 chrX:47077918-47077998 1.0000 80 chr1:25755481-25755561 1.0000 80 chr8:19674774-19674854 1.0000 80 chr6:157935171-157935251 1.0000 80 chr10:89622139-89622219 1.0000 80 chr1:31574171-31574251 1.0000 80 chr1:32253501-32253581 1.0000 80 chr12:65063059-65063139 1.0000 80 chr6:44042400-44042480 1.0000 80 chr22:23284995-23285075 1.0000 80 chr1:39851449-39851529 1.0000 80 chr16:85340472-85340552 1.0000 80 chr1:249240177-249240257 1.0000 80 chr11:96055543-96055623 1.0000 80 chr14:50328919-50328999 1.0000 80 chr1:43424904-43424984 1.0000 80 chr5:42586906-42586986 1.0000 80 chr21:38729169-38729249 1.0000 80 chr14:23775972-23776052 1.0000 80 chr6:36095447-36095527 1.0000 80 chr11:3531032-3531112 1.0000 80 chr1:52200540-52200620 1.0000 80 chr7:106806524-106806604 1.0000 80 chr8:33330656-33330736 1.0000 80 chr19:14317732-14317812 1.0000 80 chr8:42645222-42645302 1.0000 80 chr9:47187866-47187946 1.0000 80 chr8:87354633-87354713 1.0000 80 chr2:232526931-232527011 1.0000 80 chr11:125933044-12593312 1.0000 80 chr1:220263219-220263299 1.0000 80 chr18:32676044-32676124 1.0000 80 chr5:140092251-140092331 1.0000 80 chr5:96271676-96271756 1.0000 80 chr8:125488459-125488539 1.0000 80 chr10:52352823-52352903 1.0000 80 chr7:129483921-129484001 1.0000 80 chr11:62598939-62599019 1.0000 80 chr9:100809025-100809105 1.0000 80 chr19:46149481-46149561 1.0000 80 chr20:33873628-33873708 1.0000 80 chr1:155658684-155658764 1.0000 80 chr1:51985175-51985255 1.0000 80 chr17:7589717-7589797 1.0000 80 chr1:154973379-154973459 1.0000 80 chr8:107669952-107670032 1.0000 80 chr1:93250999-93251079 1.0000 80 chr6:16892166-16892246 1.0000 80 chr1:16467427-16467507 1.0000 80 chr1:142816381-142816461 1.0000 80 chr1:1677859-1677939 1.0000 80 chr16:55786929-55787009 1.0000 80 chr8:144043107-144043187 1.0000 80 chr17:81006503-81006583 1.0000 80 chr16:302824-302904 1.0000 80 chr15:89482167-89482247 1.0000 80 chr13:76112083-76112163 1.0000 80 chr6:27115917-27115997 1.0000 80 chr21:38711057-38711137 1.0000 80 chr1:182308970-182309050 1.0000 80 chr17:61072953-61073033 1.0000 80 chr10:52115958-52116038 1.0000 80 chr6:28923485-28923565 1.0000 80 chr22:23391142-23391222 1.0000 80 chr9:126091863-126091943 1.0000 80 chr6:27568920-27569000 1.0000 80 chr2:10423745-10423825 1.0000 80 chr1:100731235-100731315 1.0000 80 chr6:37175902-37175982 1.0000 80 chr8:38226182-38226262 1.0000 80 chr2:167214300-167214380 1.0000 80 chr17:17140630-17140710 1.0000 80 chr6:6886800-6886880 1.0000 80 chr19:55678320-55678400 1.0000 80 chr7:126307672-126307752 1.0000 80 chr17:4153206-4153286 1.0000 80 chr3:195891508-195891588 1.0000 80 chr5:95043432-95043512 1.0000 80 chr5:141062015-141062095 1.0000 80 chr12:107349204-10734928 1.0000 80 chr11:1331147-1331227 1.0000 80 chr12:56695088-56695168 1.0000 80 chr1:206612636-206612716 1.0000 80 chr20:33292780-33292860 1.0000 80 chr2:136287233-136287313 1.0000 80 chr15:64385300-64385380 1.0000 80 chr1:45205104-45205184 1.0000 80 chr1:65945696-65945776 1.0000 80 chr1:43609308-43609388 1.0000 80 chr7:16305941-16306021 1.0000 80 chr6:15037208-15037288 1.0000 80 chr6:37096423-37096503 1.0000 80 chrX:135968533-135968613 1.0000 80 chr19:42806730-42806810 1.0000 80 chr7:158658399-158658479 1.0000 80 chr22:20881331-20881411 1.0000 80 chr4:42659401-42659481 1.0000 80 chr19:51871227-51871307 1.0000 80 chr15:64752644-64752724 1.0000 80 chr10:76968189-76968269 1.0000 80 chr22:21295198-21295278 1.0000 80 chr7:158624472-158624552 1.0000 80 chr1:100715628-100715708 1.0000 80 chr19:49631190-49631270 1.0000 80 chr16:78133398-78133478 1.0000 80 chr19:345050-345130 1.0000 80 chr3:23987756-23987836 1.0000 80 chr2:70298081-70298161 1.0000 80 chr5:11546-11626 1.0000 80 chr21:33959478-33959558 1.0000 80 chr6:52860625-52860705 1.0000 80 chr15:75016482-75016562 1.0000 80 chr6:28909389-28909469 1.0000 80 chr12:106696399-10669647 1.0000 80 chr1:109841444-109841524 1.0000 80 chr15:78569194-78569274 1.0000 80 chr6:3443276-3443356 1.0000 80 chr1:27018817-27018897 1.0000 80 chr2:15693825-15693905 1.0000 80 chr1:161582527-161582607 1.0000 80 chr19:51868932-51869012 1.0000 80 chr17:34136218-34136298 1.0000 80 chr6:143489691-143489771 1.0000 80 chr19:39353232-39353312 1.0000 80 chr6:28924295-28924375 1.0000 80 chr1:148604897-148604977 1.0000 80 chr6:139696482-139696562 1.0000 80 chr15:64188260-64188340 1.0000 80 chr2:11606377-11606457 1.0000 80 chr2:219152193-219152273 1.0000 80 chr6:42194140-42194220 1.0000 80 chr7:111202695-111202775 1.0000 80 chr8:30770540-30770620 1.0000 80 chr7:132766072-132766152 1.0000 80 chr11:125495381-12549546 1.0000 80 chr6:26331741-26331821 1.0000 80 chr16:4674489-4674569 1.0000 80 chr7:106122685-106122765 1.0000 80 chr11:71423995-71424075 1.0000 80 chr12:107378603-10737868 1.0000 80 chr7:158938842-158938922 1.0000 80 chr10:98549730-98549810 1.0000 80 chr22:22378207-22378287 1.0000 80 chr6:28365614-28365694 1.0000 80 chr10:81107832-81107912 1.0000 80 chr3:179039674-179039754 1.0000 80 chr1:41177197-41177277 1.0000 80 chr5:73887728-73887808 1.0000 80 chr7:16685575-16685655 1.0000 80 chr6:34274050-34274130 1.0000 80 chr9:99181762-99181842 1.0000 80 chr9:131894152-131894232 1.0000 80 chr3:193788414-193788494 1.0000 80 chr12:121432720-12143280 1.0000 80 chr3:194277265-194277345 1.0000 80 chr15:64211387-64211467 1.0000 80 chr3:12851701-12851781 1.0000 80 chr2:135809538-135809618 1.0000 80 chr20:45264176-45264256 1.0000 80 chr16:29874632-29874712 1.0000 80 chr5:43042662-43042742 1.0000 80 chr20:42219390-42219470 1.0000 80 chr8:108323197-108323277 1.0000 80 chr3:9828332-9828412 1.0000 80 chr19:4724688-4724768 1.0000 80 chr14:75745307-75745387 1.0000 80 chr17:40896293-40896373 1.0000 80 chr11:85955695-85955775 1.0000 80 chr7:142699372-142699452 1.0000 80 chr7:92676171-92676251 1.0000 80 chr2:120301854-120301934 1.0000 80 chr6:53409857-53409937 1.0000 80 chr1:36850227-36850307 1.0000 80 chr3:141033493-141033573 1.0000 80 chr22:19157127-19157207 1.0000 80 chr19:18700336-18700416 1.0000 80 chr16:2265320-2265400 1.0000 80 chr3:44482948-44483028 1.0000 80 chr8:129569158-129569238 1.0000 80 chr15:100781934-10078201 1.0000 80 chr11:97844172-97844252 1.0000 80 chr11:59324962-59325042 1.0000 80 chr19:35656531-35656611 1.0000 80 chr1:153755875-153755955 1.0000 80 chr19:49653046-49653126 1.0000 80 chr19:39165441-39165521 1.0000 80 chr7:84451373-84451453 1.0000 80 chr3:47544755-47544835 1.0000 80 chr15:90605432-90605512 1.0000 80 chr12:116996323-11699640 1.0000 80 chr3:13690052-13690132 1.0000 80 chr2:55182799-55182879 1.0000 80 chr1:185254923-185255003 1.0000 80 chr21:38939227-38939307 1.0000 80 chr8:111907117-111907197 1.0000 80 ******************************************************************************** ******************************************************************************** COMMAND LINE SUMMARY ******************************************************************************** This information can also be useful in the event you wish to report a problem with the MEME software. command: meme -oc ../result/final_prediction/K562/inference_raw/MEME/RankLinear0.6_40_NUFIP1/ -dna -nmotifs 5 -w 8 -maxsize 250000 -nostatus ../result/final_prediction/K562/fasta/RankLinear0.6_40/NUFIP1.fasta model: mod= zoops nmotifs= 5 evt= inf objective function: em= E-value of product of p-values starts= E-value of product of p-values strands: + width: minw= 8 maxw= 8 nsites: minsites= 2 maxsites= 250 wnsites= 0.8 theta: spmap= uni spfuzz= 0.5 em: prior= dirichlet b= 0.01 maxiter= 50 distance= 1e-05 trim: wg= 11 ws= 1 endgaps= yes data: n= 20000 N= 250 sample: seed= 0 hsfrac= 0 searchsize= 20000 norand= no csites= 1000 Letter frequencies in dataset: A 0.238 C 0.27 G 0.244 T 0.248 Background letter frequencies (from file dataset with add-one prior applied): A 0.238 C 0.27 G 0.244 T 0.248 Background model order: 0 ******************************************************************************** ******************************************************************************** MOTIF AAARGAAA MEME-1 width = 8 sites = 18 llr = 168 E-value = 1.7e+001 ******************************************************************************** -------------------------------------------------------------------------------- Motif AAARGAAA MEME-1 Description -------------------------------------------------------------------------------- Simplified A aa872aaa pos.-specific C ::::2::: probability G ::236::: matrix T :::::::: bits 2.1 ** *** 1.9 ** *** 1.7 ** *** 1.4 ** *** Relative 1.2 **** *** Entropy 1.0 **** *** (13.5 bits) 0.8 **** *** 0.6 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel AAAAGAAA consensus GGA sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAARGAAA MEME-1 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr6:3443276-3443356 59 1.06e-05 GCTTTTTACC AAAAGAAA TCTAGAAAAA chr13:76112083-76112163 44 1.06e-05 ACATTGAGCT AAAAGAAA ATTATTTTAT chr11:3531032-3531112 43 1.06e-05 ctaggtgatt aaaagaaa gggagagtct chr6:157935171-157935251 9 1.06e-05 CAGAGATT AAAAGAAA AACAGTTGGG chr16:29874632-29874712 58 2.14e-05 TAGAAACGGA AAAGGAAA GGGTAAAAGA chr2:11606377-11606457 20 2.14e-05 AGAGGCTGGC AAAGGAAA AGGAAGAGGT chr4:42659401-42659481 24 2.14e-05 TCTTGCTCAG AAAGGAAA GACTGCTCTG chr7:126307672-126307752 32 2.14e-05 ACCTTAATGA AAAGGAAA AAGAATGATG chr6:26193856-26193936 32 2.14e-05 ATTTGGCAAC AAAGGAAA GGGAATAATT chr12:54682650-54682730 44 3.17e-05 ccccctgccc aaaaaaaa tacaaacatt chr6:34274050-34274130 64 4.25e-05 CCATGGAATT AAGAGAAA GCTGTTAAG chr19:39353232-39353312 2 4.25e-05 c aagagaaa gagagcaaat chr2:135809538-135809618 16 5.42e-05 GGGTTGAATG AAAACAAA CCCAACATGC chr6:27568920-27569000 50 5.42e-05 TTGAAGACCA AAAACAAA AACAACAGCA chr22:23391142-23391222 33 5.42e-05 catatcagac aaaacaaa ctttaaagca chr1:142783033-142783113 32 6.47e-05 GGTACTGGAG AAAGAAAA GGTGTACAAG chr10:52115958-52116038 12 9.83e-05 gttctctact aagaaaaa ttcttctgcc chr8:107669952-107670032 25 9.83e-05 TAGAAGCCAC AAGAAAAA CTTTTCGAAA -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAARGAAA MEME-1 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr6:3443276-3443356 1.1e-05 58_[+1]_14 chr13:76112083-76112163 1.1e-05 43_[+1]_29 chr11:3531032-3531112 1.1e-05 42_[+1]_30 chr6:157935171-157935251 1.1e-05 8_[+1]_64 chr16:29874632-29874712 2.1e-05 57_[+1]_15 chr2:11606377-11606457 2.1e-05 19_[+1]_53 chr4:42659401-42659481 2.1e-05 23_[+1]_49 chr7:126307672-126307752 2.1e-05 31_[+1]_41 chr6:26193856-26193936 2.1e-05 31_[+1]_41 chr12:54682650-54682730 3.2e-05 43_[+1]_29 chr6:34274050-34274130 4.2e-05 63_[+1]_9 chr19:39353232-39353312 4.2e-05 1_[+1]_71 chr2:135809538-135809618 5.4e-05 15_[+1]_57 chr6:27568920-27569000 5.4e-05 49_[+1]_23 chr22:23391142-23391222 5.4e-05 32_[+1]_40 chr1:142783033-142783113 6.5e-05 31_[+1]_41 chr10:52115958-52116038 9.8e-05 11_[+1]_61 chr8:107669952-107670032 9.8e-05 24_[+1]_48 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAARGAAA MEME-1 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF AAARGAAA width=8 seqs=18 chr6:3443276-3443356 ( 59) AAAAGAAA 1 chr13:76112083-76112163 ( 44) AAAAGAAA 1 chr11:3531032-3531112 ( 43) AAAAGAAA 1 chr6:157935171-157935251 ( 9) AAAAGAAA 1 chr16:29874632-29874712 ( 58) AAAGGAAA 1 chr2:11606377-11606457 ( 20) AAAGGAAA 1 chr4:42659401-42659481 ( 24) AAAGGAAA 1 chr7:126307672-126307752 ( 32) AAAGGAAA 1 chr6:26193856-26193936 ( 32) AAAGGAAA 1 chr12:54682650-54682730 ( 44) AAAAAAAA 1 chr6:34274050-34274130 ( 64) AAGAGAAA 1 chr19:39353232-39353312 ( 2) AAGAGAAA 1 chr2:135809538-135809618 ( 16) AAAACAAA 1 chr6:27568920-27569000 ( 50) AAAACAAA 1 chr22:23391142-23391222 ( 33) AAAACAAA 1 chr1:142783033-142783113 ( 32) AAAGAAAA 1 chr10:52115958-52116038 ( 12) AAGAAAAA 1 chr8:107669952-107670032 ( 25) AAGAAAAA 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAARGAAA MEME-1 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 11.7767 E= 1.7e+001 207 -1081 -1081 -1081 207 -1081 -1081 -1081 171 -1081 -13 -1081 149 -1081 45 -1081 -10 -69 132 -1081 207 -1081 -1081 -1081 207 -1081 -1081 -1081 207 -1081 -1081 -1081 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAARGAAA MEME-1 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 18 E= 1.7e+001 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.777778 0.000000 0.222222 0.000000 0.666667 0.000000 0.333333 0.000000 0.222222 0.166667 0.611111 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAARGAAA MEME-1 regular expression -------------------------------------------------------------------------------- AA[AG][AG][GA]AAA -------------------------------------------------------------------------------- Time 5.07 secs. ******************************************************************************** ******************************************************************************** MOTIF AGGGARAG MEME-2 width = 8 sites = 26 llr = 223 E-value = 1.9e+002 ******************************************************************************** -------------------------------------------------------------------------------- Motif AGGGARAG MEME-2 Description -------------------------------------------------------------------------------- Simplified A 6::2a47: pos.-specific C :::::::: probability G 3aa8:63a matrix T 2::::::: bits 2.1 ** * * 1.9 ** * * 1.7 ** * * 1.4 ** * * Relative 1.2 **** ** Entropy 1.0 ******* (12.4 bits) 0.8 ******* 0.6 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel AGGGAGAG consensus G A AG sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AGGGARAG MEME-2 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr19:42806730-42806810 41 1.17e-05 GGGTGGGGGG AGGGAGAG GCGAGACCAT chr5:141062015-141062095 9 1.17e-05 acaacctc agggagag ggacaaagag chr5:95043432-95043512 64 1.17e-05 ctcttagcta agggagag tcaattcag chr8:42645222-42645302 28 1.17e-05 tgcctgggaa agggagag ataaggctca chr11:3531032-3531112 4 1.17e-05 cta agggagag tcaattcagg chr12:54388541-54388621 33 1.17e-05 CGCGCgaggg agggagag agagggaggg chr3:13690052-13690132 20 2.30e-05 GTGTGGCTGG AGGGAAAG GTGCGGTGGG chr2:167214300-167214380 59 2.30e-05 aataccaaac agggaaag atgccacctt chr19:51871227-51871307 56 3.50e-05 CAGCGTGGCT GGGGAGAG CGGGCGCATC chr3:9828332-9828412 43 5.86e-05 ggctaccttt ggggaaag ttggagaaaa chr1:148604897-148604977 13 5.86e-05 AGAAGCAcca ggggaaag cgcgaacgca chr11:1331147-1331227 52 5.86e-05 CGCTCGGAGA AGGGAGGG AACTGTGGCC chr1:46867979-46868059 59 5.86e-05 AGGGACTGCC AGGGAGGG AAGGAGCCAG chr2:11606377-11606457 28 7.00e-05 GCAAAGGAAA AGGAAGAG GTGGAGCCGA chr17:19091383-19091463 26 7.00e-05 gaaaaccacg aggaagag aggtagcgtt chr7:66395436-66395516 12 9.38e-05 GAGTGGAAAC TGGGAGAG GATCCACCCC chr3:194277265-194277345 29 1.05e-04 GTGGTGGTGA AGGAAAAG CTTTgctttc chr9:126091863-126091943 49 1.05e-04 tctgagttct aggaaaag gtgtcaccac chr10:52352823-52352903 69 1.17e-04 gagatacacg tgggaaag aact chr21:38729169-38729249 10 1.17e-04 tgtttagcc tgggaaag tcacagcttg chr17:7589717-7589797 60 1.29e-04 ATTCAAAGAA GGGGAGGG ATTGAGGTTT chr19:46149481-46149561 70 1.29e-04 TGGGGGAAAA GGGGAGGG TAC chr2:55182799-55182879 54 1.53e-04 TGACCTCCCA GGGGAAGG TTAGAGGAGC chr6:3443276-3443356 18 1.76e-04 GCTGTTCCCT GGGAAAAG TAGGCCCTCA chr7:132766072-132766152 36 1.88e-04 ACTGTGGGGC TGGGAGGG AGGATGACAG chr15:70403732-70403812 60 1.99e-04 ACAGCTCTGG AGGAAAGG ACTCCAGTAC -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AGGGARAG MEME-2 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr19:42806730-42806810 1.2e-05 40_[+2]_32 chr5:141062015-141062095 1.2e-05 8_[+2]_64 chr5:95043432-95043512 1.2e-05 63_[+2]_9 chr8:42645222-42645302 1.2e-05 27_[+2]_45 chr11:3531032-3531112 1.2e-05 3_[+2]_69 chr12:54388541-54388621 1.2e-05 32_[+2]_40 chr3:13690052-13690132 2.3e-05 19_[+2]_53 chr2:167214300-167214380 2.3e-05 58_[+2]_14 chr19:51871227-51871307 3.5e-05 55_[+2]_17 chr3:9828332-9828412 5.9e-05 42_[+2]_30 chr1:148604897-148604977 5.9e-05 12_[+2]_60 chr11:1331147-1331227 5.9e-05 51_[+2]_21 chr1:46867979-46868059 5.9e-05 58_[+2]_14 chr2:11606377-11606457 7e-05 27_[+2]_45 chr17:19091383-19091463 7e-05 25_[+2]_47 chr7:66395436-66395516 9.4e-05 11_[+2]_61 chr3:194277265-194277345 0.0001 28_[+2]_44 chr9:126091863-126091943 0.0001 48_[+2]_24 chr10:52352823-52352903 0.00012 68_[+2]_4 chr21:38729169-38729249 0.00012 9_[+2]_63 chr17:7589717-7589797 0.00013 59_[+2]_13 chr19:46149481-46149561 0.00013 69_[+2]_3 chr2:55182799-55182879 0.00015 53_[+2]_19 chr6:3443276-3443356 0.00018 17_[+2]_55 chr7:132766072-132766152 0.00019 35_[+2]_37 chr15:70403732-70403812 0.0002 59_[+2]_13 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AGGGARAG MEME-2 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF AGGGARAG width=8 seqs=26 chr19:42806730-42806810 ( 41) AGGGAGAG 1 chr5:141062015-141062095 ( 9) AGGGAGAG 1 chr5:95043432-95043512 ( 64) AGGGAGAG 1 chr8:42645222-42645302 ( 28) AGGGAGAG 1 chr11:3531032-3531112 ( 4) AGGGAGAG 1 chr12:54388541-54388621 ( 33) AGGGAGAG 1 chr3:13690052-13690132 ( 20) AGGGAAAG 1 chr2:167214300-167214380 ( 59) AGGGAAAG 1 chr19:51871227-51871307 ( 56) GGGGAGAG 1 chr3:9828332-9828412 ( 43) GGGGAAAG 1 chr1:148604897-148604977 ( 13) GGGGAAAG 1 chr11:1331147-1331227 ( 52) AGGGAGGG 1 chr1:46867979-46868059 ( 59) AGGGAGGG 1 chr2:11606377-11606457 ( 28) AGGAAGAG 1 chr17:19091383-19091463 ( 26) AGGAAGAG 1 chr7:66395436-66395516 ( 12) TGGGAGAG 1 chr3:194277265-194277345 ( 29) AGGAAAAG 1 chr9:126091863-126091943 ( 49) AGGAAAAG 1 chr10:52352823-52352903 ( 69) TGGGAAAG 1 chr21:38729169-38729249 ( 10) TGGGAAAG 1 chr17:7589717-7589797 ( 60) GGGGAGGG 1 chr19:46149481-46149561 ( 70) GGGGAGGG 1 chr2:55182799-55182879 ( 54) GGGGAAGG 1 chr6:3443276-3443356 ( 18) GGGAAAAG 1 chr7:132766072-132766152 ( 36) TGGGAGGG 1 chr15:70403732-70403812 ( 60) AGGAAAGG 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AGGGARAG MEME-2 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 11.3895 E= 1.9e+002 128 -1134 14 -69 -1134 -1134 204 -1134 -1134 -1134 204 -1134 -4 -1134 166 -1134 207 -1134 -1134 -1134 83 -1134 124 -1134 162 -1134 14 -1134 -1134 -1134 204 -1134 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AGGGARAG MEME-2 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 26 E= 1.9e+002 0.576923 0.000000 0.269231 0.153846 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.230769 0.000000 0.769231 0.000000 1.000000 0.000000 0.000000 0.000000 0.423077 0.000000 0.576923 0.000000 0.730769 0.000000 0.269231 0.000000 0.000000 0.000000 1.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AGGGARAG MEME-2 regular expression -------------------------------------------------------------------------------- [AG]GG[GA]A[GA][AG]G -------------------------------------------------------------------------------- Time 8.90 secs. ******************************************************************************** ******************************************************************************** MOTIF AGGARGGA MEME-3 width = 8 sites = 13 llr = 126 E-value = 5.6e+003 ******************************************************************************** -------------------------------------------------------------------------------- Motif AGGARGGA MEME-3 Description -------------------------------------------------------------------------------- Simplified A a::84::8 pos.-specific C :::2:::: probability G :aa:6aa2 matrix T :::::::: bits 2.1 *** ** 1.9 *** ** 1.7 *** ** 1.4 **** ** Relative 1.2 **** *** Entropy 1.0 ******** (14.0 bits) 0.8 ******** 0.6 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel AGGAGGGA consensus A G sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AGGARGGA MEME-3 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr5:95043432-95043512 8 1.17e-05 gtccttg aggaggga gctgccagtg chr6:37175902-37175982 33 1.17e-05 accggagtag aggaggga cttgatctga chr9:126091863-126091943 71 1.17e-05 caccacaata aggaggga gg chr12:54388541-54388621 56 1.17e-05 gagggcgaga aggaggga gggagggaag chr16:29874632-29874712 19 2.30e-05 GAGGAGAGGG AGGAAGGA ACCATTAACG chrX:135968533-135968613 64 2.30e-05 TGTGCAAAGC AGGAAGGA AGAAGGGAA chr17:39656109-39656189 67 2.30e-05 AGTTAGGACC AGGAAGGA CATTAT chr17:29035871-29035951 4 2.30e-05 GAA AGGAAGGA AACTCCAGCA chr7:132766072-132766152 73 3.50e-05 AGTGGGTGGG AGGAGGGG chr8:19674774-19674854 53 3.50e-05 TTCTCAGAAG AGGAGGGG ACCGGGCGGT chr2:11606377-11606457 53 4.66e-05 CGAATTCCAG AGGAAGGG AACAGGGGTG chr3:193788414-193788494 73 5.99e-05 GCTACCGTGC AGGCGGGA chr16:85340472-85340552 21 5.99e-05 TGTTCATAAA AGGCGGGA GCATACAGGC -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AGGARGGA MEME-3 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr5:95043432-95043512 1.2e-05 7_[+3]_65 chr6:37175902-37175982 1.2e-05 32_[+3]_40 chr9:126091863-126091943 1.2e-05 70_[+3]_2 chr12:54388541-54388621 1.2e-05 55_[+3]_17 chr16:29874632-29874712 2.3e-05 18_[+3]_54 chrX:135968533-135968613 2.3e-05 63_[+3]_9 chr17:39656109-39656189 2.3e-05 66_[+3]_6 chr17:29035871-29035951 2.3e-05 3_[+3]_69 chr7:132766072-132766152 3.5e-05 72_[+3] chr8:19674774-19674854 3.5e-05 52_[+3]_20 chr2:11606377-11606457 4.7e-05 52_[+3]_20 chr3:193788414-193788494 6e-05 72_[+3] chr16:85340472-85340552 6e-05 20_[+3]_52 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AGGARGGA MEME-3 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF AGGARGGA width=8 seqs=13 chr5:95043432-95043512 ( 8) AGGAGGGA 1 chr6:37175902-37175982 ( 33) AGGAGGGA 1 chr9:126091863-126091943 ( 71) AGGAGGGA 1 chr12:54388541-54388621 ( 56) AGGAGGGA 1 chr16:29874632-29874712 ( 19) AGGAAGGA 1 chrX:135968533-135968613 ( 64) AGGAAGGA 1 chr17:39656109-39656189 ( 67) AGGAAGGA 1 chr17:29035871-29035951 ( 4) AGGAAGGA 1 chr7:132766072-132766152 ( 73) AGGAGGGG 1 chr8:19674774-19674854 ( 53) AGGAGGGG 1 chr2:11606377-11606457 ( 53) AGGAAGGG 1 chr3:193788414-193788494 ( 73) AGGCGGGA 1 chr16:85340472-85340552 ( 21) AGGCGGGA 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AGGARGGA MEME-3 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 11.6191 E= 5.6e+003 207 -1035 -1035 -1035 -1035 -1035 204 -1035 -1035 -1035 204 -1035 183 -81 -1035 -1035 69 -1035 133 -1035 -1035 -1035 204 -1035 -1035 -1035 204 -1035 169 -1035 -8 -1035 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AGGARGGA MEME-3 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 13 E= 5.6e+003 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.846154 0.153846 0.000000 0.000000 0.384615 0.000000 0.615385 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.769231 0.000000 0.230769 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AGGARGGA MEME-3 regular expression -------------------------------------------------------------------------------- AGGA[GA]GG[AG] -------------------------------------------------------------------------------- Time 12.68 secs. ******************************************************************************** ******************************************************************************** MOTIF AGGCWGGT MEME-4 width = 8 sites = 9 llr = 95 E-value = 4.9e+003 ******************************************************************************** -------------------------------------------------------------------------------- Motif AGGCWGGT MEME-4 Description -------------------------------------------------------------------------------- Simplified A a:::3::: pos.-specific C :::a:::: probability G :aa::aa: matrix T ::::7::a bits 2.1 *** *** 1.9 **** *** 1.7 **** *** 1.4 **** *** Relative 1.2 **** *** Entropy 1.0 ******** (15.2 bits) 0.8 ******** 0.6 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel AGGCTGGT consensus A sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AGGCWGGT MEME-4 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr3:23987756-23987836 40 1.40e-05 GCGCCTGGGG AGGCTGGT AGCTGCATAC chr2:136287233-136287313 61 1.40e-05 catgttgccc aggctggt ctcgaactcc chr7:126307672-126307752 51 1.40e-05 AGAATGATGT AGGCTGGT GAGCCAGGCC chr1:16467427-16467507 8 1.40e-05 gttgccc aggctggt ctcttgacct chr22:39925317-39925397 67 1.40e-05 TCCTCGAGCC AGGCTGGT CCTGCA chr1:28655094-28655174 34 1.40e-05 catcttggcc aggctggt ctcgaactcc chr7:132766072-132766152 10 2.75e-05 AGCCGCCCC AGGCAGGT CAGAAAAGAC chr2:219152193-219152273 7 2.75e-05 aggccg aggcaggt ggatcacgag chr17:36754955-36755035 5 2.75e-05 ACCG AGGCAGGT GGCCTGGGCT -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AGGCWGGT MEME-4 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr3:23987756-23987836 1.4e-05 39_[+4]_33 chr2:136287233-136287313 1.4e-05 60_[+4]_12 chr7:126307672-126307752 1.4e-05 50_[+4]_22 chr1:16467427-16467507 1.4e-05 7_[+4]_65 chr22:39925317-39925397 1.4e-05 66_[+4]_6 chr1:28655094-28655174 1.4e-05 33_[+4]_39 chr7:132766072-132766152 2.7e-05 9_[+4]_63 chr2:219152193-219152273 2.7e-05 6_[+4]_66 chr17:36754955-36755035 2.7e-05 4_[+4]_68 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AGGCWGGT MEME-4 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF AGGCWGGT width=8 seqs=9 chr3:23987756-23987836 ( 40) AGGCTGGT 1 chr2:136287233-136287313 ( 61) AGGCTGGT 1 chr7:126307672-126307752 ( 51) AGGCTGGT 1 chr1:16467427-16467507 ( 8) AGGCTGGT 1 chr22:39925317-39925397 ( 67) AGGCTGGT 1 chr1:28655094-28655174 ( 34) AGGCTGGT 1 chr7:132766072-132766152 ( 10) AGGCAGGT 1 chr2:219152193-219152273 ( 7) AGGCAGGT 1 chr17:36754955-36755035 ( 5) AGGCAGGT 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AGGCWGGT MEME-4 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 11.1193 E= 4.9e+003 207 -982 -982 -982 -982 -982 203 -982 -982 -982 203 -982 -982 189 -982 -982 49 -982 -982 142 -982 -982 203 -982 -982 -982 203 -982 -982 -982 -982 201 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AGGCWGGT MEME-4 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 9 E= 4.9e+003 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.333333 0.000000 0.000000 0.666667 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 1.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AGGCWGGT MEME-4 regular expression -------------------------------------------------------------------------------- AGGC[TA]GGT -------------------------------------------------------------------------------- Time 16.45 secs. ******************************************************************************** ******************************************************************************** MOTIF GGAGCCAG MEME-5 width = 8 sites = 8 llr = 85 E-value = 1.4e+004 ******************************************************************************** -------------------------------------------------------------------------------- Motif GGAGCCAG MEME-5 Description -------------------------------------------------------------------------------- Simplified A ::a:::a: pos.-specific C ::::8a:: probability G aa:a3::a matrix T :::::::: bits 2.1 **** ** 1.9 **** *** 1.7 **** *** 1.4 **** *** Relative 1.2 **** *** Entropy 1.0 ******** (15.3 bits) 0.8 ******** 0.6 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel GGAGCCAG consensus G sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GGAGCCAG MEME-5 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr2:55182799-55182879 67 1.46e-05 GAAGGTTAGA GGAGCCAG GGCTTT chr8:30770540-30770620 29 1.46e-05 CGCCGGGGGC GGAGCCAG AGGCCCTGCA chr8:33330656-33330736 71 1.46e-05 GCGTTCCGGC GGAGCCAG CC chr12:53297256-53297336 64 1.46e-05 ATGCCTCCCA GGAGCCAG TCAGCGTGA chr17:36754955-36755035 27 1.46e-05 TGGGCTACCA GGAGCCAG GATAAGGCTG chr1:46867979-46868059 69 1.46e-05 AGGGAGGGAA GGAGCCAG Agcg chr16:55786929-55787009 58 2.79e-05 gacacagtga ggaggcag cagtctgcaa chr17:39656109-39656189 14 2.79e-05 TGTGGAGCAT GGAGGCAG GGAGGCCAGT -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GGAGCCAG MEME-5 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr2:55182799-55182879 1.5e-05 66_[+5]_6 chr8:30770540-30770620 1.5e-05 28_[+5]_44 chr8:33330656-33330736 1.5e-05 70_[+5]_2 chr12:53297256-53297336 1.5e-05 63_[+5]_9 chr17:36754955-36755035 1.5e-05 26_[+5]_46 chr1:46867979-46868059 1.5e-05 68_[+5]_4 chr16:55786929-55787009 2.8e-05 57_[+5]_15 chr17:39656109-39656189 2.8e-05 13_[+5]_59 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GGAGCCAG MEME-5 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF GGAGCCAG width=8 seqs=8 chr2:55182799-55182879 ( 67) GGAGCCAG 1 chr8:30770540-30770620 ( 29) GGAGCCAG 1 chr8:33330656-33330736 ( 71) GGAGCCAG 1 chr12:53297256-53297336 ( 64) GGAGCCAG 1 chr17:36754955-36755035 ( 27) GGAGCCAG 1 chr1:46867979-46868059 ( 69) GGAGCCAG 1 chr16:55786929-55787009 ( 58) GGAGGCAG 1 chr17:39656109-39656189 ( 14) GGAGGCAG 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GGAGCCAG MEME-5 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 10.3065 E= 1.4e+004 -965 -965 203 -965 -965 -965 203 -965 207 -965 -965 -965 -965 -965 203 -965 -965 147 4 -965 -965 189 -965 -965 207 -965 -965 -965 -965 -965 203 -965 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GGAGCCAG MEME-5 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 8 E= 1.4e+004 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.750000 0.250000 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GGAGCCAG MEME-5 regular expression -------------------------------------------------------------------------------- GGAG[CG]CAG -------------------------------------------------------------------------------- Time 20.18 secs. ******************************************************************************** ******************************************************************************** SUMMARY OF MOTIFS ******************************************************************************** -------------------------------------------------------------------------------- Combined block diagrams: non-overlapping sites with p-value < 0.0001 -------------------------------------------------------------------------------- SEQUENCE NAME COMBINED P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr7:158317045-158317125 7.16e-01 80 chr9:132164077-132164157 1.00e+00 80 chr12:54388541-54388621 2.29e-05 32_[+2(1.17e-05)]_2_[+2(5.86e-05)]_\ 5_[+3(1.17e-05)]_3_[+2(8.16e-05)]_6 chr19:14318414-14318494 4.37e-02 80 chr1:10739817-10739897 3.91e-01 80 chr17:19015575-19015655 2.76e-01 80 chr18:61034946-61035026 5.81e-01 80 chr17:19091383-19091463 1.46e-02 25_[+2(7.00e-05)]_47 chr12:108999511-10899959 3.59e-01 80 chr2:96917555-96917635 3.34e-01 80 chr15:70403732-70403812 5.36e-02 80 chr19:12947212-12947292 3.48e-03 80 chrX:65383971-65384051 5.40e-01 80 chr1:46867979-46868059 1.07e-04 58_[+2(5.86e-05)]_2_[+5(1.46e-05)]_\ 4 chr6:160147314-160147394 1.00e+00 80 chrX:152419847-152419927 9.54e-01 80 chr3:197071907-197071987 9.99e-01 80 chr17:74016050-74016130 8.12e-01 80 chr12:108999974-10900005 4.19e-01 80 chr1:17566023-17566103 9.46e-01 80 chr7:66395436-66395516 7.60e-02 11_[+2(9.38e-05)]_61 chr9:2241973-2242053 3.51e-01 80 chr17:29035871-29035951 6.68e-04 3_[+3(2.30e-05)]_69 chr17:44269422-44269502 5.71e-01 80 chr12:54682650-54682730 9.81e-03 43_[+1(3.17e-05)]_29 chr8:144152496-144152576 5.73e-02 80 chr15:93444566-93444646 5.39e-01 80 chr17:36754955-36755035 1.12e-04 4_[+4(2.75e-05)]_14_[+5(1.46e-05)]_\ 46 chr12:53297256-53297336 8.62e-02 63_[+5(1.46e-05)]_9 chr7:32702205-32702285 7.18e-01 80 chr1:10039-10119 1.00e+00 80 chr5:81253972-81254052 9.62e-01 80 chr17:18967112-18967192 9.39e-02 80 chr3:197161044-197161124 1.00e+00 80 chr17:39656109-39656189 2.58e-05 13_[+5(2.79e-05)]_45_[+3(2.30e-05)]_\ 6 chr1:142783033-142783113 8.15e-03 31_[+1(6.47e-05)]_41 chr1:114491684-114491764 4.49e-01 80 chr1:28655094-28655174 6.65e-03 33_[+4(1.40e-05)]_39 chr11:61348959-61349039 6.68e-01 80 chr6:37017304-37017384 8.55e-01 80 chr22:39925317-39925397 1.15e-02 66_[+4(1.40e-05)]_6 chr1:27013471-27013551 9.16e-01 80 chr22:20115745-20115825 9.48e-01 80 chrX:129300133-129300213 5.88e-01 80 chr12:74686555-74686635 1.00e+00 80 chr6:26193856-26193936 1.49e-03 31_[+1(2.14e-05)]_41 chr8:38008417-38008497 6.61e-01 80 chr1:21672981-21673061 9.44e-01 80 chrX:153236079-153236159 1.00e+00 80 chr1:249184753-249184833 3.18e-01 80 chr6:34244784-34244864 1.00e+00 80 chr3:156271870-156271950 9.41e-01 80 chr6:28986045-28986125 9.49e-01 80 chr1:179851218-179851298 1.86e-01 80 chr17:38225323-38225403 1.00e+00 80 chrX:47077918-47077998 9.99e-01 80 chr1:25755481-25755561 1.83e-01 80 chr8:19674774-19674854 2.60e-02 52_[+3(3.50e-05)]_20 chr6:157935171-157935251 2.38e-03 8_[+1(1.06e-05)]_64 chr10:89622139-89622219 8.55e-01 80 chr1:31574171-31574251 5.63e-02 80 chr1:32253501-32253581 8.38e-02 80 chr12:65063059-65063139 7.85e-01 80 chr6:44042400-44042480 2.26e-01 80 chr22:23284995-23285075 1.00e+00 80 chr1:39851449-39851529 5.79e-01 80 chr16:85340472-85340552 2.74e-02 20_[+3(5.99e-05)]_52 chr1:249240177-249240257 7.76e-01 80 chr11:96055543-96055623 7.59e-02 80 chr14:50328919-50328999 6.62e-02 80 chr1:43424904-43424984 8.64e-02 80 chr5:42586906-42586986 2.18e-01 80 chr21:38729169-38729249 4.26e-02 80 chr14:23775972-23776052 9.87e-01 80 chr6:36095447-36095527 1.40e-01 80 chr11:3531032-3531112 3.51e-05 3_[+2(1.17e-05)]_31_[+1(1.06e-05)]_\ 30 chr1:52200540-52200620 5.03e-01 80 chr7:106806524-106806604 6.76e-01 80 chr8:33330656-33330736 3.17e-03 70_[+5(1.46e-05)]_2 chr19:14317732-14317812 2.32e-01 80 chr8:42645222-42645302 5.64e-03 27_[+2(1.17e-05)]_45 chr9:47187866-47187946 9.80e-01 80 chr8:87354633-87354713 9.27e-01 80 chr2:232526931-232527011 6.57e-01 80 chr11:125933044-12593312 6.32e-02 80 chr1:220263219-220263299 5.12e-01 80 chr18:32676044-32676124 2.26e-01 80 chr5:140092251-140092331 2.83e-01 80 chr5:96271676-96271756 9.17e-01 80 chr8:125488459-125488539 3.49e-01 80 chr10:52352823-52352903 4.88e-03 80 chr7:129483921-129484001 1.00e+00 80 chr11:62598939-62599019 1.47e-01 80 chr9:100809025-100809105 2.07e-01 80 chr19:46149481-46149561 2.50e-02 80 chr20:33873628-33873708 6.48e-01 80 chr1:155658684-155658764 5.71e-01 80 chr1:51985175-51985255 4.25e-01 80 chr17:7589717-7589797 1.30e-02 80 chr1:154973379-154973459 3.12e-02 80 chr8:107669952-107670032 1.53e-01 24_[+1(9.83e-05)]_48 chr1:93250999-93251079 1.74e-01 80 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