******************************************************************************** MEME - Motif discovery tool ******************************************************************************** MEME version 5.3.3 (Release date: Sun Feb 7 15:39:52 2021 -0800) For further information on how to interpret these results please access https://meme-suite.org/meme. To get a copy of the MEME Suite software please access https://meme-suite.org. ******************************************************************************** ******************************************************************************** REFERENCE ******************************************************************************** If you use this program in your research, please cite: Timothy L. Bailey and Charles Elkan, "Fitting a mixture model by expectation maximization to discover motifs in biopolymers", Proceedings of the Second International Conference on Intelligent Systems for Molecular Biology, pp. 28-36, AAAI Press, Menlo Park, California, 1994. ******************************************************************************** ******************************************************************************** TRAINING SET ******************************************************************************** PRIMARY SEQUENCES= ../result/final_prediction/K562/fasta/RankLinear0.6_40/NR0B1.fasta CONTROL SEQUENCES= --none-- ALPHABET= ACGT Sequence name Weight Length Sequence name Weight Length ------------- ------ ------ ------------- ------ ------ chr22:23066217-23066297 1.0000 80 chr22:22354260-22354340 1.0000 80 chr22:19306946-19307026 1.0000 80 chr22:17291747-17291827 1.0000 80 chr22:23187085-23187165 1.0000 80 chr6:160521233-160521313 1.0000 80 chr2:170725110-170725190 1.0000 80 chr18:19322732-19322812 1.0000 80 chr7:149186314-149186394 1.0000 80 chr7:143670551-143670631 1.0000 80 chr22:22847874-22847954 1.0000 80 chr22:23321510-23321590 1.0000 80 chr12:104679689-10467976 1.0000 80 chr22:23320522-23320602 1.0000 80 chr10:52116572-52116652 1.0000 80 chr22:23126502-23126582 1.0000 80 chr1:144911917-144911997 1.0000 80 chr22:23120830-23120910 1.0000 80 chr6:15482649-15482729 1.0000 80 chr22:22938280-22938360 1.0000 80 chr22:23122374-23122454 1.0000 80 chr10:63341367-63341447 1.0000 80 chr22:22425569-22425649 1.0000 80 chr12:77175701-77175781 1.0000 80 chr22:21192729-21192809 1.0000 80 chr22:23071765-23071845 1.0000 80 chr13:90554557-90554637 1.0000 80 chr13:90698722-90698802 1.0000 80 chr15:65825730-65825810 1.0000 80 chr9:66458880-66458960 1.0000 80 chr7:64839576-64839656 1.0000 80 chr22:23184812-23184892 1.0000 80 chr13:92393764-92393844 1.0000 80 chr1:248625829-248625909 1.0000 80 chr6:12013841-12013921 1.0000 80 chr22:23120027-23120107 1.0000 80 chr7:104747311-104747391 1.0000 80 chr7:96318690-96318770 1.0000 80 chr1:142781782-142781862 1.0000 80 chr10:73807979-73808059 1.0000 80 chr2:87591441-87591521 1.0000 80 chr19:6111810-6111890 1.0000 80 chr7:157017983-157018063 1.0000 80 chr5:36983076-36983156 1.0000 80 chr22:22956221-22956301 1.0000 80 chr22:22395440-22395520 1.0000 80 chr22:22957819-22957899 1.0000 80 chr6:161411857-161411937 1.0000 80 chr1:168256965-168257045 1.0000 80 chr7:151668315-151668395 1.0000 80 chr22:23348972-23349052 1.0000 80 chr22:23341820-23341900 1.0000 80 chr13:91468712-91468792 1.0000 80 chr22:22397048-22397128 1.0000 80 chr22:22953307-22953387 1.0000 80 chr22:22944176-22944256 1.0000 80 chr7:106258160-106258240 1.0000 80 chr22:22417231-22417311 1.0000 80 chr1:114347117-114347197 1.0000 80 chr22:20324294-20324374 1.0000 80 chr1:24059581-24059661 1.0000 80 chr7:92263592-92263672 1.0000 80 chr6:99841327-99841407 1.0000 80 chr1:144890354-144890434 1.0000 80 chr22:23174118-23174198 1.0000 80 chr9:115574323-115574403 1.0000 80 chr1:207863293-207863373 1.0000 80 chr6:13679699-13679779 1.0000 80 chr1:114416310-114416390 1.0000 80 chr22:19618069-19618149 1.0000 80 chr22:19078048-19078128 1.0000 80 chr2:170766695-170766775 1.0000 80 chr13:91890991-91891071 1.0000 80 chr2:91739733-91739813 1.0000 80 chr7:130912068-130912148 1.0000 80 chr9:140222796-140222876 1.0000 80 chr22:22852462-22852542 1.0000 80 chr19:19373034-19373114 1.0000 80 chr7:135745851-135745931 1.0000 80 chr1:182227447-182227527 1.0000 80 chr13:92131764-92131844 1.0000 80 chr22:21095198-21095278 1.0000 80 chr22:22436789-22436869 1.0000 80 chr7:126617393-126617473 1.0000 80 chr15:44116365-44116445 1.0000 80 chr2:169833721-169833801 1.0000 80 chr10:76779111-76779191 1.0000 80 chr7:2890260-2890340 1.0000 80 chr22:22381939-22382019 1.0000 80 chr22:19220396-19220476 1.0000 80 chr8:97266541-97266621 1.0000 80 chr22:22248665-22248745 1.0000 80 chr1:172455858-172455938 1.0000 80 chr22:23340315-23340395 1.0000 80 chr6:149645302-149645382 1.0000 80 chrX:70774999-70775079 1.0000 80 chr10:63512483-63512563 1.0000 80 chr1:52202242-52202322 1.0000 80 chr3:169849767-169849847 1.0000 80 chr22:19200157-19200237 1.0000 80 chr22:17109383-17109463 1.0000 80 chr7:107227873-107227953 1.0000 80 chr16:33342462-33342542 1.0000 80 chr1:93814162-93814242 1.0000 80 chr16:32343199-32343279 1.0000 80 chr3:5486031-5486111 1.0000 80 chr1:26452565-26452645 1.0000 80 chr22:20084737-20084817 1.0000 80 chr7:152079648-152079728 1.0000 80 chr17:40405522-40405602 1.0000 80 chr1:121142753-121142833 1.0000 80 chr7:157180439-157180519 1.0000 80 chr7:111126485-111126565 1.0000 80 chr21:39488023-39488103 1.0000 80 chr12:62702410-62702490 1.0000 80 chr1:172712024-172712104 1.0000 80 chr22:23182413-23182493 1.0000 80 chr15:43577769-43577849 1.0000 80 chr13:92364655-92364735 1.0000 80 chr22:23308059-23308139 1.0000 80 chr1:145102116-145102196 1.0000 80 chr1:241970792-241970872 1.0000 80 chr9:126852487-126852567 1.0000 80 chr1:192954811-192954891 1.0000 80 chr22:22815699-22815779 1.0000 80 chr20:34330233-34330313 1.0000 80 chr1:20907130-20907210 1.0000 80 chr10:22519049-22519129 1.0000 80 chr13:91046851-91046931 1.0000 80 chr6:17584866-17584946 1.0000 80 chr1:148850069-148850149 1.0000 80 chr7:100782363-100782443 1.0000 80 chr6:26382937-26383017 1.0000 80 chr8:27062998-27063078 1.0000 80 chr7:64459074-64459154 1.0000 80 chr7:29788410-29788490 1.0000 80 chr22:22168641-22168721 1.0000 80 chr1:231539981-231540061 1.0000 80 chr3:16592930-16593010 1.0000 80 chr1:233771284-233771364 1.0000 80 chr6:119613819-119613899 1.0000 80 chr18:731013-731093 1.0000 80 chr9:104211077-104211157 1.0000 80 chr13:93064167-93064247 1.0000 80 chr11:46016742-46016822 1.0000 80 chr1:142819812-142819892 1.0000 80 chr22:22846248-22846328 1.0000 80 chr2:159071544-159071624 1.0000 80 chr7:150624474-150624554 1.0000 80 chr22:22690694-22690774 1.0000 80 chr7:127029224-127029304 1.0000 80 chr7:128117615-128117695 1.0000 80 chr22:23392690-23392770 1.0000 80 chr8:117768393-117768473 1.0000 80 chr6:135396218-135396298 1.0000 80 chr22:22797491-22797571 1.0000 80 chr22:23083810-23083890 1.0000 80 chr1:100791975-100792055 1.0000 80 chr6:45398822-45398902 1.0000 80 chr7:106240418-106240498 1.0000 80 chr1:113447346-113447426 1.0000 80 chr1:142789789-142789869 1.0000 80 chr13:92163420-92163500 1.0000 80 chr6:13993825-13993905 1.0000 80 chr7:111165733-111165813 1.0000 80 chr2:175259546-175259626 1.0000 80 chr22:22132087-22132167 1.0000 80 chr17:37617678-37617758 1.0000 80 chr3:48031154-48031234 1.0000 80 chr22:21441323-21441403 1.0000 80 chr22:22428031-22428111 1.0000 80 chr17:56736375-56736455 1.0000 80 chr22:19063397-19063477 1.0000 80 chr3:43625308-43625388 1.0000 80 chr6:28304734-28304814 1.0000 80 chr4:57333015-57333095 1.0000 80 chr22:22200002-22200082 1.0000 80 chr13:81366316-81366396 1.0000 80 chr6:13980888-13980968 1.0000 80 chr11:341054-341134 1.0000 80 chr11:112007951-11200803 1.0000 80 chr7:130478390-130478470 1.0000 80 chr6:43872763-43872843 1.0000 80 chr13:91260003-91260083 1.0000 80 chr13:81456644-81456724 1.0000 80 chr22:22483997-22484077 1.0000 80 chr1:180023934-180024014 1.0000 80 chr1:223960321-223960401 1.0000 80 chr21:11057082-11057162 1.0000 80 chr3:41250074-41250154 1.0000 80 chr1:203766723-203766803 1.0000 80 chr5:53459736-53459816 1.0000 80 chr1:233654082-233654162 1.0000 80 chr7:153111505-153111585 1.0000 80 chr8:27541400-27541480 1.0000 80 chr1:224016139-224016219 1.0000 80 chr13:81364237-81364317 1.0000 80 chr1:51657677-51657757 1.0000 80 chr6:15308957-15309037 1.0000 80 chr19:53399089-53399169 1.0000 80 chr6:27257659-27257739 1.0000 80 chr7:158989279-158989359 1.0000 80 chr7:138729596-138729676 1.0000 80 chr6:2416520-2416600 1.0000 80 chr6:37393884-37393964 1.0000 80 chr13:91824578-91824658 1.0000 80 chr7:3310116-3310196 1.0000 80 chr8:90771087-90771167 1.0000 80 chr22:22134372-22134452 1.0000 80 chr1:227568186-227568266 1.0000 80 chr22:22510931-22511011 1.0000 80 chr7:107093120-107093200 1.0000 80 chr1:52961451-52961531 1.0000 80 chr17:63036737-63036817 1.0000 80 chr6:15879238-15879318 1.0000 80 chr1:145085646-145085726 1.0000 80 chr7:138702324-138702404 1.0000 80 chr19:50639102-50639182 1.0000 80 chr7:116106321-116106401 1.0000 80 chr7:106717545-106717625 1.0000 80 chr2:145109055-145109135 1.0000 80 chr1:7629551-7629631 1.0000 80 chr6:36563427-36563507 1.0000 80 chr7:129516737-129516817 1.0000 80 chr1:120676961-120677041 1.0000 80 chr13:92113818-92113898 1.0000 80 chr22:19326707-19326787 1.0000 80 chr10:27446496-27446576 1.0000 80 chr20:52370594-52370674 1.0000 80 chr13:91278216-91278296 1.0000 80 chr17:36370515-36370595 1.0000 80 chr7:158694824-158694904 1.0000 80 chr8:27631359-27631439 1.0000 80 chr22:22404208-22404288 1.0000 80 chr17:72510888-72510968 1.0000 80 chr2:181923888-181923968 1.0000 80 chr22:21015942-21016022 1.0000 80 chr6:27721472-27721552 1.0000 80 chr22:22447511-22447591 1.0000 80 chr1:202451779-202451859 1.0000 80 chr16:90062632-90062712 1.0000 80 chr22:23338031-23338111 1.0000 80 chr1:20163528-20163608 1.0000 80 chr1:109622050-109622130 1.0000 80 chr22:22133685-22133765 1.0000 80 chr15:66112531-66112611 1.0000 80 chr4:127701694-127701774 1.0000 80 chr13:91455444-91455524 1.0000 80 chr6:34643618-34643698 1.0000 80 chr7:155110224-155110304 1.0000 80 ******************************************************************************** ******************************************************************************** COMMAND LINE SUMMARY ******************************************************************************** This information can also be useful in the event you wish to report a problem with the MEME software. command: meme -oc ../result/final_prediction/K562/inference_raw/MEME/RankLinear0.6_40_NR0B1/ -dna -nmotifs 5 -w 8 -maxsize 250000 -nostatus ../result/final_prediction/K562/fasta/RankLinear0.6_40/NR0B1.fasta model: mod= zoops nmotifs= 5 evt= inf objective function: em= E-value of product of p-values starts= E-value of product of p-values strands: + width: minw= 8 maxw= 8 nsites: minsites= 2 maxsites= 250 wnsites= 0.8 theta: spmap= uni spfuzz= 0.5 em: prior= dirichlet b= 0.01 maxiter= 50 distance= 1e-05 trim: wg= 11 ws= 1 endgaps= yes data: n= 20000 N= 250 sample: seed= 0 hsfrac= 0 searchsize= 20000 norand= no csites= 1000 Letter frequencies in dataset: A 0.338 C 0.164 G 0.175 T 0.323 Background letter frequencies (from file dataset with add-one prior applied): A 0.338 C 0.164 G 0.175 T 0.323 Background model order: 0 ******************************************************************************** ******************************************************************************** MOTIF TYTTTCYY MEME-1 width = 8 sites = 42 llr = 337 E-value = 3.5e-002 ******************************************************************************** -------------------------------------------------------------------------------- Motif TYTTTCYY MEME-1 Description -------------------------------------------------------------------------------- Simplified A :::::::: pos.-specific C :522:a64 probability G :::::::: matrix T a588a:46 bits 2.6 * 2.3 * 2.1 * 1.8 * Relative 1.6 * ** Entropy 1.3 * *** (11.6 bits) 1.0 ******** 0.8 ******** 0.5 ******** 0.3 ******** 0.0 -------- Multilevel TCTTTCCT consensus TC TC sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TYTTTCYY MEME-1 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr1:202451779-202451859 21 7.87e-06 ttgcaaattt tctttccc atcctttagg chr9:126852487-126852567 69 7.87e-06 tctttccctt tctttccc ttcc chr6:2416520-2416600 58 2.34e-05 tttctctctt tctttcct tccttccttc chr11:112007951-11200803 60 2.34e-05 cttttttctt tctttcct tcctttcttt chr6:13993825-13993905 46 2.34e-05 CTCCCttctt tctttcct tccttctttc chr1:100791975-100792055 62 2.34e-05 tttctctctc tctttcct tccttccttc chr22:22815699-22815779 46 2.34e-05 CTTGACTAAA tctttcct gcaattgtta chr7:130912068-130912148 38 2.34e-05 ttcttttctt tctttcct tctctctctt chr22:23184812-23184892 48 2.34e-05 ttagttgtgt tctttcct gctcaaataa chr22:22938280-22938360 8 2.34e-05 CCATACT TCTTTCCT GAGAATATAT chr1:233654082-233654162 3 3.93e-05 gt tctctccc caacatctcc chr1:182227447-182227527 9 3.93e-05 tccttcct tctctccc tccctccctc chr13:92163420-92163500 3 5.48e-05 tc tttttccc tcttcggtac chr9:115574323-115574403 56 5.48e-05 CTGGCTCTAC TTTTTCCC TCTGTCCTTG chr19:50639102-50639182 52 9.32e-05 gatcttgtct tttttcct ttattaatct chr13:91890991-91891071 51 9.32e-05 TGTTTTTAAT TTTTTCCT GAGTAATATT chr1:207863293-207863373 52 9.32e-05 tttttgcttc tttttcct taattagttt chr12:77175701-77175781 44 9.32e-05 CACCTTAGCG TTTTTCCT GGAGCCTAAA chr3:41250074-41250154 69 9.52e-05 aacaatcttg tccctccc tggc chr1:223960321-223960401 56 9.52e-05 TTTTCTCTAC TCCCTCCC CGTTTAAGAT chr6:15879238-15879318 34 1.19e-04 ttacctgttt ttcttccc aatagactct chr7:107093120-107093200 37 1.19e-04 aaaccgtttt ttcttccc agtctcgggt chr7:138729596-138729676 27 1.19e-04 GTTATTTCGT TCTTTCTC TTATATACAA chr6:27257659-27257739 31 1.19e-04 AGGAATTGAA TTCTTCCC TTTAAAAATA chr22:23071765-23071845 48 1.23e-04 TTGCTACGTG TCCCTCCT CTAATACGGC chr15:66112531-66112611 66 1.77e-04 ttctctcttt tctttctt tctcttt chr6:43872763-43872843 66 1.77e-04 ttctcttctt tctttctt tcttttc chr13:81366316-81366396 68 1.77e-04 tttctttctt tctttctt tcttt chr3:43625308-43625388 7 1.77e-04 ACAGTA TCTTTCTT AAAGAAAATG chr7:157180439-157180519 22 1.77e-04 TCCTAAGGAA TCTTTCTT GTGAAAATTT chr9:66458880-66458960 4 1.77e-04 ctt ttcttcct gattgaagta chr13:90554557-90554637 70 1.77e-04 atagttttat ttcttcct taa chr13:81364237-81364317 36 1.92e-04 TGTGCACAGG TTTCTCCT AAAGTATAAA chr20:52370594-52370674 12 2.27e-04 tgtctctctc tctctctc tctctctctc chr22:22428031-22428111 46 2.58e-04 TGATATATGT TTTTTCTC TCGAGAAAGT chr22:23320522-23320602 52 2.58e-04 gacctttata tttttctc ttcttaaatt chr22:19063397-19063477 17 2.81e-04 ggtgtacaaa tctctctt caagtctctg chr6:37393884-37393964 12 3.41e-04 gctccagaat tttttctt gtttcttttt chr5:53459736-53459816 39 3.41e-04 gtttaatcca tttttctt ccagttccct chr7:130478390-130478470 39 3.41e-04 aattctggtc tttttctt ccatgttgtg chr16:32343199-32343279 3 3.61e-04 at ttcttctc atctcatttc chr22:17109383-17109463 38 4.15e-04 tagttttcat ttcttctt agattttcat -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TYTTTCYY MEME-1 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr1:202451779-202451859 7.9e-06 20_[+1]_52 chr9:126852487-126852567 7.9e-06 68_[+1]_4 chr6:2416520-2416600 2.3e-05 57_[+1]_15 chr11:112007951-11200803 2.3e-05 59_[+1]_13 chr6:13993825-13993905 2.3e-05 45_[+1]_27 chr1:100791975-100792055 2.3e-05 61_[+1]_11 chr22:22815699-22815779 2.3e-05 45_[+1]_27 chr7:130912068-130912148 2.3e-05 37_[+1]_35 chr22:23184812-23184892 2.3e-05 47_[+1]_25 chr22:22938280-22938360 2.3e-05 7_[+1]_65 chr1:233654082-233654162 3.9e-05 2_[+1]_70 chr1:182227447-182227527 3.9e-05 8_[+1]_64 chr13:92163420-92163500 5.5e-05 2_[+1]_70 chr9:115574323-115574403 5.5e-05 55_[+1]_17 chr19:50639102-50639182 9.3e-05 51_[+1]_21 chr13:91890991-91891071 9.3e-05 50_[+1]_22 chr1:207863293-207863373 9.3e-05 51_[+1]_21 chr12:77175701-77175781 9.3e-05 43_[+1]_29 chr3:41250074-41250154 9.5e-05 68_[+1]_4 chr1:223960321-223960401 9.5e-05 55_[+1]_17 chr6:15879238-15879318 0.00012 33_[+1]_39 chr7:107093120-107093200 0.00012 36_[+1]_36 chr7:138729596-138729676 0.00012 26_[+1]_46 chr6:27257659-27257739 0.00012 30_[+1]_42 chr22:23071765-23071845 0.00012 47_[+1]_25 chr15:66112531-66112611 0.00018 65_[+1]_7 chr6:43872763-43872843 0.00018 65_[+1]_7 chr13:81366316-81366396 0.00018 67_[+1]_5 chr3:43625308-43625388 0.00018 6_[+1]_66 chr7:157180439-157180519 0.00018 21_[+1]_51 chr9:66458880-66458960 0.00018 3_[+1]_69 chr13:90554557-90554637 0.00018 69_[+1]_3 chr13:81364237-81364317 0.00019 35_[+1]_37 chr20:52370594-52370674 0.00023 11_[+1]_61 chr22:22428031-22428111 0.00026 45_[+1]_27 chr22:23320522-23320602 0.00026 51_[+1]_21 chr22:19063397-19063477 0.00028 16_[+1]_56 chr6:37393884-37393964 0.00034 11_[+1]_61 chr5:53459736-53459816 0.00034 38_[+1]_34 chr7:130478390-130478470 0.00034 38_[+1]_34 chr16:32343199-32343279 0.00036 2_[+1]_70 chr22:17109383-17109463 0.00041 37_[+1]_35 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TYTTTCYY MEME-1 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF TYTTTCYY width=8 seqs=42 chr1:202451779-202451859 ( 21) TCTTTCCC 1 chr9:126852487-126852567 ( 69) TCTTTCCC 1 chr6:2416520-2416600 ( 58) TCTTTCCT 1 chr11:112007951-11200803 ( 60) TCTTTCCT 1 chr6:13993825-13993905 ( 46) TCTTTCCT 1 chr1:100791975-100792055 ( 62) TCTTTCCT 1 chr22:22815699-22815779 ( 46) TCTTTCCT 1 chr7:130912068-130912148 ( 38) TCTTTCCT 1 chr22:23184812-23184892 ( 48) TCTTTCCT 1 chr22:22938280-22938360 ( 8) TCTTTCCT 1 chr1:233654082-233654162 ( 3) TCTCTCCC 1 chr1:182227447-182227527 ( 9) TCTCTCCC 1 chr13:92163420-92163500 ( 3) TTTTTCCC 1 chr9:115574323-115574403 ( 56) TTTTTCCC 1 chr19:50639102-50639182 ( 52) TTTTTCCT 1 chr13:91890991-91891071 ( 51) TTTTTCCT 1 chr1:207863293-207863373 ( 52) TTTTTCCT 1 chr12:77175701-77175781 ( 44) TTTTTCCT 1 chr3:41250074-41250154 ( 69) TCCCTCCC 1 chr1:223960321-223960401 ( 56) TCCCTCCC 1 chr6:15879238-15879318 ( 34) TTCTTCCC 1 chr7:107093120-107093200 ( 37) TTCTTCCC 1 chr7:138729596-138729676 ( 27) TCTTTCTC 1 chr6:27257659-27257739 ( 31) TTCTTCCC 1 chr22:23071765-23071845 ( 48) TCCCTCCT 1 chr15:66112531-66112611 ( 66) TCTTTCTT 1 chr6:43872763-43872843 ( 66) TCTTTCTT 1 chr13:81366316-81366396 ( 68) TCTTTCTT 1 chr3:43625308-43625388 ( 7) TCTTTCTT 1 chr7:157180439-157180519 ( 22) TCTTTCTT 1 chr9:66458880-66458960 ( 4) TTCTTCCT 1 chr13:90554557-90554637 ( 70) TTCTTCCT 1 chr13:81364237-81364317 ( 36) TTTCTCCT 1 chr20:52370594-52370674 ( 12) TCTCTCTC 1 chr22:22428031-22428111 ( 46) TTTTTCTC 1 chr22:23320522-23320602 ( 52) TTTTTCTC 1 chr22:19063397-19063477 ( 17) TCTCTCTT 1 chr6:37393884-37393964 ( 12) TTTTTCTT 1 chr5:53459736-53459816 ( 39) TTTTTCTT 1 chr7:130478390-130478470 ( 39) TTTTTCTT 1 chr16:32343199-32343279 ( 3) TTCTTCTC 1 chr22:17109383-17109463 ( 38) TTCTTCTT 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TYTTTCYY MEME-1 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 10.8329 E= 3.5e-002 -1204 -1204 -1204 163 -1204 174 -1204 49 -1204 53 -1204 124 -1204 21 -1204 133 -1204 -1204 -1204 163 -1204 260 -1204 -1204 -1204 197 -1204 15 -1204 121 -1204 94 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TYTTTCYY MEME-1 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 42 E= 3.5e-002 0.000000 0.000000 0.000000 1.000000 0.000000 0.547619 0.000000 0.452381 0.000000 0.238095 0.000000 0.761905 0.000000 0.190476 0.000000 0.809524 0.000000 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.642857 0.000000 0.357143 0.000000 0.380952 0.000000 0.619048 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TYTTTCYY MEME-1 regular expression -------------------------------------------------------------------------------- T[CT][TC]TTC[CT][TC] -------------------------------------------------------------------------------- Time 5.16 secs. ******************************************************************************** ******************************************************************************** MOTIF CCMTCMCC MEME-2 width = 8 sites = 15 llr = 147 E-value = 1.3e+001 ******************************************************************************** -------------------------------------------------------------------------------- Motif CCMTCMCC MEME-2 Description -------------------------------------------------------------------------------- Simplified A ::5::5:: pos.-specific C aa33a38a probability G ::2::::: matrix T :::7:22: bits 2.6 ** * * 2.3 ** * * 2.1 ** * * 1.8 ** * * Relative 1.6 ** * ** Entropy 1.3 ** * ** (14.2 bits) 1.0 ** ** ** 0.8 ** ** ** 0.5 ******** 0.3 ******** 0.0 -------- Multilevel CCATCACC consensus CC CT sequence G T -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCMTCMCC MEME-2 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr17:37617678-37617758 45 1.03e-06 CTGGGATTGC CCCTCCCC CCTTCCCCAA chr7:64839576-64839656 24 1.03e-06 gtgttattta ccctcccc tccccccgcc chr22:23083810-23083890 6 5.80e-06 ggtat ccatcccc tcaagcattt chr7:155110224-155110304 2 1.34e-05 a ccatcacc atcactatca chr1:51657677-51657757 47 1.34e-05 ccatatgttc ccatcacc cccatctaac chr7:2890260-2890340 50 1.34e-05 atcattatca ccatcacc atcatcacca chr2:169833721-169833801 32 1.63e-05 ataattgtca ccgtcacc aaactagact chr1:7629551-7629631 54 1.85e-05 atcatcatca ccaccacc acatcaacat chr17:63036737-63036817 22 2.17e-05 ttacaggtgc ccgccacc acgcccagct chr22:21192729-21192809 35 2.17e-05 ccttgtccta ccctctcc actaaccact chr21:39488023-39488103 3 3.12e-05 ta ccacctcc accattacta chr1:114347117-114347197 9 3.23e-05 cttcCTTT CCGCCTCC ACTATCAGAC chr7:126617393-126617473 50 3.43e-05 GTTTCTGGTA CCCTCCTC TCAGTCCTAC chr1:182227447-182227527 22 3.43e-05 ctccctccct ccctcctc tccttccttc chr8:97266541-97266621 24 5.87e-05 ttattaacta ccatcatc atgctggaca -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCMTCMCC MEME-2 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr17:37617678-37617758 1e-06 44_[+2]_28 chr7:64839576-64839656 1e-06 23_[+2]_49 chr22:23083810-23083890 5.8e-06 5_[+2]_67 chr7:155110224-155110304 1.3e-05 1_[+2]_71 chr1:51657677-51657757 1.3e-05 46_[+2]_26 chr7:2890260-2890340 1.3e-05 49_[+2]_23 chr2:169833721-169833801 1.6e-05 31_[+2]_41 chr1:7629551-7629631 1.8e-05 53_[+2]_19 chr17:63036737-63036817 2.2e-05 21_[+2]_51 chr22:21192729-21192809 2.2e-05 34_[+2]_38 chr21:39488023-39488103 3.1e-05 2_[+2]_70 chr1:114347117-114347197 3.2e-05 8_[+2]_64 chr7:126617393-126617473 3.4e-05 49_[+2]_23 chr1:182227447-182227527 3.4e-05 21_[+2]_51 chr8:97266541-97266621 5.9e-05 23_[+2]_49 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCMTCMCC MEME-2 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF CCMTCMCC width=8 seqs=15 chr17:37617678-37617758 ( 45) CCCTCCCC 1 chr7:64839576-64839656 ( 24) CCCTCCCC 1 chr22:23083810-23083890 ( 6) CCATCCCC 1 chr7:155110224-155110304 ( 2) CCATCACC 1 chr1:51657677-51657757 ( 47) CCATCACC 1 chr7:2890260-2890340 ( 50) CCATCACC 1 chr2:169833721-169833801 ( 32) CCGTCACC 1 chr1:7629551-7629631 ( 54) CCACCACC 1 chr17:63036737-63036817 ( 22) CCGCCACC 1 chr22:21192729-21192809 ( 35) CCCTCTCC 1 chr21:39488023-39488103 ( 3) CCACCTCC 1 chr1:114347117-114347197 ( 9) CCGCCTCC 1 chr7:126617393-126617473 ( 50) CCCTCCTC 1 chr1:182227447-182227527 ( 22) CCCTCCTC 1 chr8:97266541-97266621 ( 24) CCATCATC 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCMTCMCC MEME-2 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 11.5229 E= 1.3e+001 -1055 260 -1055 -1055 -1055 260 -1055 -1055 47 102 19 -1055 -1055 70 -1055 118 -1055 260 -1055 -1055 47 102 -1055 -69 -1055 228 -1055 -69 -1055 260 -1055 -1055 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCMTCMCC MEME-2 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 15 E= 1.3e+001 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.466667 0.333333 0.200000 0.000000 0.000000 0.266667 0.000000 0.733333 0.000000 1.000000 0.000000 0.000000 0.466667 0.333333 0.000000 0.200000 0.000000 0.800000 0.000000 0.200000 0.000000 1.000000 0.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCMTCMCC MEME-2 regular expression -------------------------------------------------------------------------------- CC[ACG][TC]C[ACT][CT]C -------------------------------------------------------------------------------- Time 9.00 secs. ******************************************************************************** ******************************************************************************** MOTIF CCSCCCGC MEME-3 width = 8 sites = 2 llr = 27 E-value = 3.0e+003 ******************************************************************************** -------------------------------------------------------------------------------- Motif CCSCCCGC MEME-3 Description -------------------------------------------------------------------------------- Simplified A :::::::: pos.-specific C aa5aaa:a probability G ::5:::a: matrix T :::::::: bits 2.6 ** ***** 2.3 ** ***** 2.1 ** ***** 1.8 ** ***** Relative 1.6 ******** Entropy 1.3 ******** (19.7 bits) 1.0 ******** 0.8 ******** 0.5 ******** 0.3 ******** 0.0 -------- Multilevel CCCCCCGC consensus G sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCSCCCGC MEME-3 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr7:64839576-64839656 33 5.58e-07 accctcccct ccccccgc caaaaatgca chr1:24059581-24059661 9 1.15e-06 caggtgat ccgcccgc cttggtctct -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCSCCCGC MEME-3 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr7:64839576-64839656 5.6e-07 32_[+3]_40 chr1:24059581-24059661 1.2e-06 8_[+3]_64 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCSCCCGC MEME-3 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF CCSCCCGC width=8 seqs=2 chr7:64839576-64839656 ( 33) CCCCCCGC 1 chr1:24059581-24059661 ( 9) CCGCCCGC 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCSCCCGC MEME-3 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 13.1555 E= 3.0e+003 -765 260 -765 -765 -765 260 -765 -765 -765 160 151 -765 -765 260 -765 -765 -765 260 -765 -765 -765 260 -765 -765 -765 -765 251 -765 -765 260 -765 -765 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCSCCCGC MEME-3 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 2 E= 3.0e+003 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.500000 0.500000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCSCCCGC MEME-3 regular expression -------------------------------------------------------------------------------- CC[CG]CCCGC -------------------------------------------------------------------------------- Time 12.79 secs. ******************************************************************************** ******************************************************************************** MOTIF CCTCCCAG MEME-4 width = 8 sites = 2 llr = 26 E-value = 1.0e+004 ******************************************************************************** -------------------------------------------------------------------------------- Motif CCTCCCAG MEME-4 Description -------------------------------------------------------------------------------- Simplified A ::::::a: pos.-specific C aa:aaa:: probability G :::::::a matrix T ::a::::: bits 2.6 ** *** * 2.3 ** *** * 2.1 ** *** * 1.8 ** *** * Relative 1.6 ******** Entropy 1.3 ******** (18.7 bits) 1.0 ******** 0.8 ******** 0.5 ******** 0.3 ******** 0.0 -------- Multilevel CCTCCCAG consensus sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCTCCCAG MEME-4 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr7:92263592-92263672 23 2.27e-06 gccgttctgt cctcccag atttgtgatt chr22:22847874-22847954 6 2.27e-06 CTCTA CCTCCCAG AAAATGTCAA -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCTCCCAG MEME-4 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr7:92263592-92263672 2.3e-06 22_[+4]_50 chr22:22847874-22847954 2.3e-06 5_[+4]_67 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCTCCCAG MEME-4 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF CCTCCCAG width=8 seqs=2 chr7:92263592-92263672 ( 23) CCTCCCAG 1 chr22:22847874-22847954 ( 6) CCTCCCAG 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCTCCCAG MEME-4 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 13.1555 E= 1.0e+004 -765 260 -765 -765 -765 260 -765 -765 -765 -765 -765 163 -765 260 -765 -765 -765 260 -765 -765 -765 260 -765 -765 156 -765 -765 -765 -765 -765 251 -765 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCTCCCAG MEME-4 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 2 E= 1.0e+004 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCTCCCAG MEME-4 regular expression -------------------------------------------------------------------------------- CCTCCCAG -------------------------------------------------------------------------------- Time 16.58 secs. ******************************************************************************** ******************************************************************************** MOTIF GRRAGARR MEME-5 width = 8 sites = 39 llr = 304 E-value = 7.8e+004 ******************************************************************************** -------------------------------------------------------------------------------- Motif GRRAGARR MEME-5 Description -------------------------------------------------------------------------------- Simplified A :679:747 pos.-specific C :::::::: probability G a431a363 matrix T :::::::: bits 2.6 * * 2.3 * * 2.1 * * 1.8 * * Relative 1.6 * * Entropy 1.3 * ** (11.2 bits) 1.0 ******** 0.8 ******** 0.5 ******** 0.3 ******** 0.0 -------- Multilevel GAAAGAGA consensus GG GAG sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GRRAGARR MEME-5 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr1:20163528-20163608 12 2.82e-05 aaacaaaaga ggaagagg aagaaagaaa chr2:145109055-145109135 45 2.82e-05 AAGATGAGAT GGAAGAGA GGGTGGGAGA chr9:104211077-104211157 5 2.82e-05 GCGA GGGAGAGa aagaaagggc chr6:26382937-26383017 25 2.82e-05 aagagagaaa ggaagaga gaggaaggaa chr1:241970792-241970872 36 2.82e-05 gggagggagg gggagaga gagagaaaga chr22:19220396-19220476 42 2.82e-05 ACATACAGAA GGAAGAGA GGGAGAGAAA chr19:19373034-19373114 20 2.82e-05 gagacagaga ggaagaga cagagaagca chr10:63341367-63341447 54 2.82e-05 gagaaagata gggagaga tgaagggagg chr7:128117615-128117695 17 4.28e-05 AAATATTGTT GGGAGGGG GGCTAATGAC chr10:52116572-52116652 73 4.28e-05 catggacaca ggaagggg chr6:27257659-27257739 16 9.73e-05 AATCAGTAGG GAAAGAGG AATTGAATTC chr11:341054-341134 71 9.73e-05 gaaggaaaag gaaagagg ag chr22:22797491-22797571 1 9.73e-05 . gaaagaga gagaaagaaa chr3:16592930-16593010 10 9.73e-05 agaaagaaa gaaagaga agaaagagga chr6:149645302-149645382 38 9.73e-05 AGGTCCTGCA GAGAGAGA GAGAGAGAAG chr7:127029224-127029304 6 1.25e-04 AGGTA GAGAGGGG AATTggggga chr1:20907130-20907210 28 1.25e-04 atgagaaata gagaggga cattatatac chr1:172712024-172712104 10 1.25e-04 ttaggaact gagagggg tgaaAGTGGG chr22:22852462-22852542 38 1.25e-04 cagaagatag gaaaggga aaatggtgag chr22:23122374-23122454 42 1.25e-04 aaggagaaaa gaaaggga cagaaaaagg chr11:46016742-46016822 69 1.80e-04 CTAATCATAG GGGAGAAA GCAC chr7:152079648-152079728 26 1.80e-04 AGCTGAATGG GGAAGAAA AGGATATTTA chr2:170766695-170766775 44 1.80e-04 agattaaata gggagaaa agagatgtga chr1:144890354-144890434 50 1.80e-04 TTCTCACCTT GGAAGAAA GACAAGGTGG chr1:142789789-142789869 21 2.08e-04 taacatttag ggaaggag gggatgatac chr7:116106321-116106401 14 3.13e-04 AGGAAAAATG GAGAGAAG AAAGTCACGT chr1:227568186-227568266 67 3.13e-04 cagaaaccat gaaagaaa aaagag chr13:91260003-91260083 14 3.13e-04 ttagaaggtg gaaagaaa tgctggtatg chr15:43577769-43577849 55 3.13e-04 GGGGAGGTAT GAAAGAAA TTCGAGGATG chr22:19200157-19200237 11 3.13e-04 aagaaagaaa gaaagaaa agaaagaaag chr1:114416310-114416390 10 3.13e-04 TAACTTTGG GAAAGAAA ATAAAAATAA chr13:91468712-91468792 17 3.13e-04 aagaagaaaa gagagaag aatcaaatag chr7:143670551-143670631 1 3.13e-04 . gaaagaaa agccatcaag chr22:23182413-23182493 68 3.82e-04 cgaaaatgct gaaaggaa aaact chr7:157180439-157180519 48 3.82e-04 TTTTTTTTGA GGAGGAGG GAGCATTCAT chr22:23120027-23120107 51 3.82e-04 aaaactacta gaaaggaa cttagagaac chr1:192954811-192954891 25 4.18e-04 gcaaagactt gaaggagg tgagagaatt chr18:731013-731093 5 4.33e-04 tcat gaaggggg tgagaagcag chr1:51657677-51657757 26 5.58e-04 caggcaacta gaggggaa tttccatatg -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GRRAGARR MEME-5 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr1:20163528-20163608 2.8e-05 11_[+5]_61 chr2:145109055-145109135 2.8e-05 44_[+5]_28 chr9:104211077-104211157 2.8e-05 4_[+5]_68 chr6:26382937-26383017 2.8e-05 24_[+5]_48 chr1:241970792-241970872 2.8e-05 35_[+5]_37 chr22:19220396-19220476 2.8e-05 41_[+5]_31 chr19:19373034-19373114 2.8e-05 19_[+5]_53 chr10:63341367-63341447 2.8e-05 53_[+5]_19 chr7:128117615-128117695 4.3e-05 16_[+5]_56 chr10:52116572-52116652 4.3e-05 72_[+5] chr6:27257659-27257739 9.7e-05 15_[+5]_57 chr11:341054-341134 9.7e-05 70_[+5]_2 chr22:22797491-22797571 9.7e-05 [+5]_72 chr3:16592930-16593010 9.7e-05 9_[+5]_63 chr6:149645302-149645382 9.7e-05 37_[+5]_35 chr7:127029224-127029304 0.00013 5_[+5]_67 chr1:20907130-20907210 0.00013 27_[+5]_45 chr1:172712024-172712104 0.00013 9_[+5]_63 chr22:22852462-22852542 0.00013 37_[+5]_35 chr22:23122374-23122454 0.00013 41_[+5]_31 chr11:46016742-46016822 0.00018 68_[+5]_4 chr7:152079648-152079728 0.00018 25_[+5]_47 chr2:170766695-170766775 0.00018 43_[+5]_29 chr1:144890354-144890434 0.00018 49_[+5]_23 chr1:142789789-142789869 0.00021 20_[+5]_52 chr7:116106321-116106401 0.00031 13_[+5]_59 chr1:227568186-227568266 0.00031 66_[+5]_6 chr13:91260003-91260083 0.00031 13_[+5]_59 chr15:43577769-43577849 0.00031 54_[+5]_18 chr22:19200157-19200237 0.00031 10_[+5]_62 chr1:114416310-114416390 0.00031 9_[+5]_63 chr13:91468712-91468792 0.00031 16_[+5]_56 chr7:143670551-143670631 0.00031 [+5]_72 chr22:23182413-23182493 0.00038 67_[+5]_5 chr7:157180439-157180519 0.00038 47_[+5]_25 chr22:23120027-23120107 0.00038 50_[+5]_22 chr1:192954811-192954891 0.00042 24_[+5]_48 chr18:731013-731093 0.00043 4_[+5]_68 chr1:51657677-51657757 0.00056 25_[+5]_47 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GRRAGARR MEME-5 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF GRRAGARR width=8 seqs=39 chr1:20163528-20163608 ( 12) GGAAGAGG 1 chr2:145109055-145109135 ( 45) GGAAGAGA 1 chr9:104211077-104211157 ( 5) GGGAGAGA 1 chr6:26382937-26383017 ( 25) GGAAGAGA 1 chr1:241970792-241970872 ( 36) GGGAGAGA 1 chr22:19220396-19220476 ( 42) GGAAGAGA 1 chr19:19373034-19373114 ( 20) GGAAGAGA 1 chr10:63341367-63341447 ( 54) GGGAGAGA 1 chr7:128117615-128117695 ( 17) GGGAGGGG 1 chr10:52116572-52116652 ( 73) GGAAGGGG 1 chr6:27257659-27257739 ( 16) GAAAGAGG 1 chr11:341054-341134 ( 71) GAAAGAGG 1 chr22:22797491-22797571 ( 1) GAAAGAGA 1 chr3:16592930-16593010 ( 10) GAAAGAGA 1 chr6:149645302-149645382 ( 38) GAGAGAGA 1 chr7:127029224-127029304 ( 6) GAGAGGGG 1 chr1:20907130-20907210 ( 28) GAGAGGGA 1 chr1:172712024-172712104 ( 10) GAGAGGGG 1 chr22:22852462-22852542 ( 38) GAAAGGGA 1 chr22:23122374-23122454 ( 42) GAAAGGGA 1 chr11:46016742-46016822 ( 69) GGGAGAAA 1 chr7:152079648-152079728 ( 26) GGAAGAAA 1 chr2:170766695-170766775 ( 44) GGGAGAAA 1 chr1:144890354-144890434 ( 50) GGAAGAAA 1 chr1:142789789-142789869 ( 21) GGAAGGAG 1 chr7:116106321-116106401 ( 14) GAGAGAAG 1 chr1:227568186-227568266 ( 67) GAAAGAAA 1 chr13:91260003-91260083 ( 14) GAAAGAAA 1 chr15:43577769-43577849 ( 55) GAAAGAAA 1 chr22:19200157-19200237 ( 11) GAAAGAAA 1 chr1:114416310-114416390 ( 10) GAAAGAAA 1 chr13:91468712-91468792 ( 17) GAGAGAAG 1 chr7:143670551-143670631 ( 1) GAAAGAAA 1 chr22:23182413-23182493 ( 68) GAAAGGAA 1 chr7:157180439-157180519 ( 48) GGAGGAGG 1 chr22:23120027-23120107 ( 51) GAAAGGAA 1 chr1:192954811-192954891 ( 25) GAAGGAGG 1 chr18:731013-731093 ( 5) GAAGGGGG 1 chr1:51657677-51657757 ( 26) GAGGGGAA 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GRRAGARR MEME-5 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 10.6953 E= 7.8e+004 -1193 -1193 251 -1193 80 -1193 123 -1193 98 -1193 93 -1193 141 -1193 -77 -1193 -1193 -1193 251 -1193 104 -1193 81 -1193 28 -1193 175 -1193 98 -1193 93 -1193 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GRRAGARR MEME-5 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 39 E= 7.8e+004 0.000000 0.000000 1.000000 0.000000 0.589744 0.000000 0.410256 0.000000 0.666667 0.000000 0.333333 0.000000 0.897436 0.000000 0.102564 0.000000 0.000000 0.000000 1.000000 0.000000 0.692308 0.000000 0.307692 0.000000 0.410256 0.000000 0.589744 0.000000 0.666667 0.000000 0.333333 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GRRAGARR MEME-5 regular expression -------------------------------------------------------------------------------- G[AG][AG]AG[AG][GA][AG] -------------------------------------------------------------------------------- Time 20.37 secs. ******************************************************************************** ******************************************************************************** SUMMARY OF MOTIFS ******************************************************************************** -------------------------------------------------------------------------------- Combined block diagrams: non-overlapping sites with p-value < 0.0001 -------------------------------------------------------------------------------- SEQUENCE NAME COMBINED P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr22:23066217-23066297 9.99e-01 80 chr22:22354260-22354340 9.19e-01 80 chr22:19306946-19307026 3.10e-01 80 chr22:17291747-17291827 2.21e-01 80 chr22:23187085-23187165 6.68e-01 80 chr6:160521233-160521313 9.98e-01 80 chr2:170725110-170725190 5.67e-02 80 chr18:19322732-19322812 5.31e-01 80 chr7:149186314-149186394 9.60e-01 80 chr7:143670551-143670631 2.02e-01 80 chr22:22847874-22847954 4.30e-04 5_[+4(2.27e-06)]_67 chr22:23321510-23321590 9.99e-01 80 chr12:104679689-10467976 5.54e-01 80 chr22:23320522-23320602 5.20e-01 80 chr10:52116572-52116652 3.03e-02 72_[+5(4.28e-05)] chr22:23126502-23126582 7.40e-01 80 chr1:144911917-144911997 2.70e-01 80 chr22:23120830-23120910 8.41e-01 80 chr6:15482649-15482729 9.57e-01 80 chr22:22938280-22938360 3.78e-05 7_[+1(2.34e-05)]_37_[+4(7.99e-05)]_\ 20 chr22:23122374-23122454 4.87e-01 80 chr10:63341367-63341447 2.61e-01 17_[+5(4.28e-05)]_28_[+5(2.82e-05)]_\ 19 chr22:22425569-22425649 9.96e-01 80 chr12:77175701-77175781 2.09e-01 43_[+1(9.32e-05)]_29 chr22:21192729-21192809 1.14e-03 34_[+2(2.17e-05)]_38 chr22:23071765-23071845 1.53e-04 48_[+2(3.43e-05)]_24 chr13:90554557-90554637 4.65e-01 80 chr13:90698722-90698802 8.78e-01 80 chr15:65825730-65825810 9.91e-01 80 chr9:66458880-66458960 1.20e-01 80 chr7:64839576-64839656 4.03e-08 23_[+2(1.03e-06)]_1_[+3(5.58e-07)]_\ 40 chr22:23184812-23184892 6.86e-02 47_[+1(2.34e-05)]_25 chr13:92393764-92393844 9.98e-01 80 chr1:248625829-248625909 6.43e-01 80 chr6:12013841-12013921 9.56e-01 80 chr22:23120027-23120107 3.02e-01 80 chr7:104747311-104747391 8.37e-01 80 chr7:96318690-96318770 6.88e-01 80 chr1:142781782-142781862 8.46e-01 80 chr10:73807979-73808059 1.20e-02 80 chr2:87591441-87591521 9.97e-01 80 chr19:6111810-6111890 1.69e-02 80 chr7:157017983-157018063 5.79e-01 80 chr5:36983076-36983156 8.59e-01 80 chr22:22956221-22956301 5.24e-01 80 chr22:22395440-22395520 9.91e-01 80 chr22:22957819-22957899 5.89e-01 80 chr6:161411857-161411937 1.00e+00 80 chr1:168256965-168257045 8.56e-01 80 chr7:151668315-151668395 7.41e-01 80 chr22:23348972-23349052 9.99e-01 80 chr22:23341820-23341900 9.19e-01 80 chr13:91468712-91468792 8.98e-02 80 chr22:22397048-22397128 6.72e-01 80 chr22:22953307-22953387 9.97e-01 80 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********************************************************************************