******************************************************************************** MEME - Motif discovery tool ******************************************************************************** MEME version 5.3.3 (Release date: Sun Feb 7 15:39:52 2021 -0800) For further information on how to interpret these results please access https://meme-suite.org/meme. To get a copy of the MEME Suite software please access https://meme-suite.org. ******************************************************************************** ******************************************************************************** REFERENCE ******************************************************************************** If you use this program in your research, please cite: Timothy L. Bailey and Charles Elkan, "Fitting a mixture model by expectation maximization to discover motifs in biopolymers", Proceedings of the Second International Conference on Intelligent Systems for Molecular Biology, pp. 28-36, AAAI Press, Menlo Park, California, 1994. ******************************************************************************** ******************************************************************************** TRAINING SET ******************************************************************************** PRIMARY SEQUENCES= ../result/final_prediction/K562/fasta/RankLinear0.6_40/NCOA1.fasta CONTROL SEQUENCES= --none-- ALPHABET= ACGT Sequence name Weight Length Sequence name Weight Length ------------- ------ ------ ------------- ------ ------ chr7:6543433-6543513 1.0000 80 chr16:517616-517696 1.0000 80 chr16:517816-517896 1.0000 80 chr19:1123170-1123250 1.0000 80 chr2:17699738-17699818 1.0000 80 chr12:132166853-13216693 1.0000 80 chr13:114428190-11442827 1.0000 80 chr16:22202026-22202106 1.0000 80 chr6:169825686-169825766 1.0000 80 chr16:89359965-89360045 1.0000 80 chr9:130981143-130981223 1.0000 80 chr17:11876215-11876295 1.0000 80 chr19:4328486-4328566 1.0000 80 chr9:102907628-102907708 1.0000 80 chr2:242823863-242823943 1.0000 80 chr14:21852248-21852328 1.0000 80 chr3:152949165-152949245 1.0000 80 chr16:22202235-22202315 1.0000 80 chr17:4843528-4843608 1.0000 80 chr4:95309280-95309360 1.0000 80 chr19:18747420-18747500 1.0000 80 chr17:549357-549437 1.0000 80 chr14:88491085-88491165 1.0000 80 chr16:1393181-1393261 1.0000 80 chr8:144302022-144302102 1.0000 80 chr1:169337252-169337332 1.0000 80 chr2:242824077-242824157 1.0000 80 chr1:35602548-35602628 1.0000 80 chr3:49131519-49131599 1.0000 80 chr4:129566589-129566669 1.0000 80 chr6:142337978-142338058 1.0000 80 chr6:82915905-82915985 1.0000 80 chr14:35122457-35122537 1.0000 80 chr10:51565111-51565191 1.0000 80 chr14:102144480-10214456 1.0000 80 chr9:140044931-140045011 1.0000 80 chr1:25611742-25611822 1.0000 80 chr17:62919208-62919288 1.0000 80 chr11:71639559-71639639 1.0000 80 chr9:98637851-98637931 1.0000 80 chr3:171164805-171164885 1.0000 80 chr7:7082273-7082353 1.0000 80 chr16:89259045-89259125 1.0000 80 chr6:44355224-44355304 1.0000 80 chr19:2151746-2151826 1.0000 80 chr11:68391362-68391442 1.0000 80 chr12:101673920-10167400 1.0000 80 chr1:244436430-244436510 1.0000 80 chrX:40032082-40032162 1.0000 80 chr10:4892023-4892103 1.0000 80 chr17:53046026-53046106 1.0000 80 chr2:178483550-178483630 1.0000 80 chr19:1490729-1490809 1.0000 80 chr20:9129838-9129918 1.0000 80 chr10:51565312-51565392 1.0000 80 chr4:144940578-144940658 1.0000 80 chr6:35995408-35995488 1.0000 80 chr20:23113758-23113838 1.0000 80 chr17:53894317-53894397 1.0000 80 chr15:56612693-56612773 1.0000 80 chr2:219433404-219433484 1.0000 80 chr6:30585391-30585471 1.0000 80 chr5:131450380-131450460 1.0000 80 chr1:25606332-25606412 1.0000 80 chr1:211395910-211395990 1.0000 80 chr9:125209239-125209319 1.0000 80 chr15:78730331-78730411 1.0000 80 chr8:93107702-93107782 1.0000 80 chr19:49999420-49999500 1.0000 80 chr6:42012091-42012171 1.0000 80 chrX:10087619-10087699 1.0000 80 chr9:35004446-35004526 1.0000 80 chr9:73100399-73100479 1.0000 80 chr7:105752869-105752949 1.0000 80 chr22:40316291-40316371 1.0000 80 chr8:98790762-98790842 1.0000 80 chr6:16263865-16263945 1.0000 80 chr8:126954478-126954558 1.0000 80 chr8:38068325-38068405 1.0000 80 chr1:160919195-160919275 1.0000 80 chr9:136159297-136159377 1.0000 80 chr16:70470017-70470097 1.0000 80 chr12:49351266-49351346 1.0000 80 chr19:45909735-45909815 1.0000 80 chr2:192701665-192701745 1.0000 80 chr19:42612812-42612892 1.0000 80 chr2:25479546-25479626 1.0000 80 chr4:54232173-54232253 1.0000 80 chr7:129409107-129409187 1.0000 80 chr19:47760522-47760602 1.0000 80 chr12:29534127-29534207 1.0000 80 chr9:140513122-140513202 1.0000 80 chr2:219712513-219712593 1.0000 80 chr4:25052514-25052594 1.0000 80 chr19:18747625-18747705 1.0000 80 chr11:67764443-67764523 1.0000 80 chr7:104607695-104607775 1.0000 80 chr1:78148349-78148429 1.0000 80 chr9:35728596-35728676 1.0000 80 chr9:4863144-4863224 1.0000 80 chr6:28514944-28515024 1.0000 80 chr3:47388933-47389013 1.0000 80 chr4:17812523-17812603 1.0000 80 chr1:70005893-70005973 1.0000 80 chr5:131651365-131651445 1.0000 80 chr12:123237304-12323738 1.0000 80 chr13:44972132-44972212 1.0000 80 chr3:126630368-126630448 1.0000 80 chr10:5024331-5024411 1.0000 80 chrX:65218094-65218174 1.0000 80 chr17:37617609-37617689 1.0000 80 chr9:4862945-4863025 1.0000 80 chr14:20645713-20645793 1.0000 80 chr13:95923636-95923716 1.0000 80 chr4:69730308-69730388 1.0000 80 chr19:10812040-10812120 1.0000 80 chr12:4262871-4262951 1.0000 80 chr1:15110688-15110768 1.0000 80 chr3:32115890-32115970 1.0000 80 chr2:86416691-86416771 1.0000 80 chr6:27741819-27741899 1.0000 80 chr12:114404045-11440412 1.0000 80 chr1:25739903-25739983 1.0000 80 chr5:131987933-131988013 1.0000 80 chr7:43026528-43026608 1.0000 80 chrX:151345707-151345787 1.0000 80 chr11:12171498-12171578 1.0000 80 chr3:14162496-14162576 1.0000 80 chr17:60311538-60311618 1.0000 80 chr17:4167238-4167318 1.0000 80 chr20:17906256-17906336 1.0000 80 chr16:20685563-20685643 1.0000 80 chrX:119468573-119468653 1.0000 80 chr5:176421945-176422025 1.0000 80 chr4:1884780-1884860 1.0000 80 chr13:95923435-95923515 1.0000 80 chr6:125404414-125404494 1.0000 80 chr8:130594485-130594565 1.0000 80 chr7:65580469-65580549 1.0000 80 chr11:125423010-12542309 1.0000 80 chr2:172865174-172865254 1.0000 80 chr20:33780336-33780416 1.0000 80 chrX:49100807-49100887 1.0000 80 chr18:67693006-67693086 1.0000 80 chr9:101694447-101694527 1.0000 80 chr15:22833365-22833445 1.0000 80 chr5:131332575-131332655 1.0000 80 chr14:36733954-36734034 1.0000 80 chr18:968420-968500 1.0000 80 chr22:23624100-23624180 1.0000 80 chr19:47931506-47931586 1.0000 80 chr5:148018813-148018893 1.0000 80 chr20:46012907-46012987 1.0000 80 chr16:23833435-23833515 1.0000 80 chr13:109421983-10942206 1.0000 80 chr6:119863385-119863465 1.0000 80 chr8:130705177-130705257 1.0000 80 chr2:169990948-169991028 1.0000 80 chr3:195805977-195806057 1.0000 80 chr5:180209025-180209105 1.0000 80 chr5:1067938-1068018 1.0000 80 chr12:58165792-58165872 1.0000 80 chr18:8913728-8913808 1.0000 80 chr9:138842307-138842387 1.0000 80 chr19:516748-516828 1.0000 80 chr14:31291375-31291455 1.0000 80 chr2:198794145-198794225 1.0000 80 chr4:80131432-80131512 1.0000 80 chr2:230786990-230787070 1.0000 80 chr19:52051129-52051209 1.0000 80 chr22:22818576-22818656 1.0000 80 chr5:131649930-131650010 1.0000 80 chr6:37151148-37151228 1.0000 80 chr4:81100942-81101022 1.0000 80 chr1:156571205-156571285 1.0000 80 chr22:32022697-32022777 1.0000 80 chr19:35411469-35411549 1.0000 80 chrX:102356735-102356815 1.0000 80 chr8:37939595-37939675 1.0000 80 chr14:102414492-10241457 1.0000 80 chr9:38171075-38171155 1.0000 80 chr4:68418035-68418115 1.0000 80 chr5:89940148-89940228 1.0000 80 chr3:46530358-46530438 1.0000 80 chr3:49398931-49399011 1.0000 80 chr14:69186595-69186675 1.0000 80 chr4:56596106-56596186 1.0000 80 chr3:98302749-98302829 1.0000 80 chr1:61514693-61514773 1.0000 80 chr22:37948841-37948921 1.0000 80 chr12:116823781-11682386 1.0000 80 chr11:5186199-5186279 1.0000 80 chr2:191049369-191049449 1.0000 80 chr14:55221585-55221665 1.0000 80 chr1:201528951-201529031 1.0000 80 chr7:92515504-92515584 1.0000 80 chr19:21785809-21785889 1.0000 80 chr19:7894851-7894931 1.0000 80 chr12:133047863-13304794 1.0000 80 chr9:138360882-138360962 1.0000 80 chr3:16977885-16977965 1.0000 80 chr13:38533669-38533749 1.0000 80 chr7:75943706-75943786 1.0000 80 chr4:144826750-144826830 1.0000 80 chr8:20809653-20809733 1.0000 80 chr3:125152066-125152146 1.0000 80 chr18:77361320-77361400 1.0000 80 chr12:92798821-92798901 1.0000 80 chr5:39194731-39194811 1.0000 80 chr20:34330251-34330331 1.0000 80 chr16:11196068-11196148 1.0000 80 chr1:19923371-19923451 1.0000 80 chr4:15683210-15683290 1.0000 80 chr13:111617760-11161784 1.0000 80 chr16:25783263-25783343 1.0000 80 chr17:27717290-27717370 1.0000 80 chr17:40714081-40714161 1.0000 80 chr22:36764702-36764782 1.0000 80 chr8:37949384-37949464 1.0000 80 chr2:677400-677480 1.0000 80 chr7:77502870-77502950 1.0000 80 chr3:5468212-5468292 1.0000 80 chr3:195577851-195577931 1.0000 80 chr15:51944717-51944797 1.0000 80 chr19:14618685-14618765 1.0000 80 chr16:15615895-15615975 1.0000 80 chr4:144775958-144776038 1.0000 80 chr2:43154850-43154930 1.0000 80 chrX:11479838-11479918 1.0000 80 chr6:52168905-52168985 1.0000 80 chr3:4266828-4266908 1.0000 80 chr17:65852270-65852350 1.0000 80 chr13:25968978-25969058 1.0000 80 chr15:66097594-66097674 1.0000 80 chr19:4247672-4247752 1.0000 80 chr1:27226906-27226986 1.0000 80 chr6:53224467-53224547 1.0000 80 chr1:5946022-5946102 1.0000 80 chr3:141567992-141568072 1.0000 80 chr3:186589330-186589410 1.0000 80 chr2:38871051-38871131 1.0000 80 chr5:98290521-98290601 1.0000 80 chr11:107885883-10788596 1.0000 80 chr10:29295066-29295146 1.0000 80 chr8:37749448-37749528 1.0000 80 chr1:65696954-65697034 1.0000 80 chr2:145199439-145199519 1.0000 80 chr13:27557249-27557329 1.0000 80 chr17:57367827-57367907 1.0000 80 chr2:32853230-32853310 1.0000 80 ******************************************************************************** ******************************************************************************** COMMAND LINE SUMMARY ******************************************************************************** This information can also be useful in the event you wish to report a problem with the MEME software. command: meme -oc ../result/final_prediction/K562/inference_raw/MEME/RankLinear0.6_40_NCOA1/ -dna -nmotifs 5 -w 8 -maxsize 250000 -nostatus ../result/final_prediction/K562/fasta/RankLinear0.6_40/NCOA1.fasta model: mod= zoops nmotifs= 5 evt= inf objective function: em= E-value of product of p-values starts= E-value of product of p-values strands: + width: minw= 8 maxw= 8 nsites: minsites= 2 maxsites= 250 wnsites= 0.8 theta: spmap= uni spfuzz= 0.5 em: prior= dirichlet b= 0.01 maxiter= 50 distance= 1e-05 trim: wg= 11 ws= 1 endgaps= yes data: n= 20000 N= 250 sample: seed= 0 hsfrac= 0 searchsize= 20000 norand= no csites= 1000 Letter frequencies in dataset: A 0.24 C 0.255 G 0.266 T 0.239 Background letter frequencies (from file dataset with add-one prior applied): A 0.241 C 0.255 G 0.266 T 0.239 Background model order: 0 ******************************************************************************** ******************************************************************************** MOTIF SAGATAAG MEME-1 width = 8 sites = 75 llr = 571 E-value = 7.3e-024 ******************************************************************************** -------------------------------------------------------------------------------- Motif SAGATAAG MEME-1 Description -------------------------------------------------------------------------------- Simplified A 17:a:a91 pos.-specific C 41:::::1 probability G 4:a:::17 matrix T 12::a::1 bits 2.1 * 1.9 **** 1.7 **** 1.4 ***** Relative 1.2 ***** Entropy 1.0 ****** (11.0 bits) 0.8 ****** 0.6 ******* 0.4 ******* 0.2 ******** 0.0 -------- Multilevel CAGATAAG consensus GT sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif SAGATAAG MEME-1 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr8:37949384-37949464 55 1.45e-05 ctggtgagta cagataag gcttgctgag chr16:25783263-25783343 69 1.45e-05 tgtaaaggga cagataag aatt chr19:52051129-52051209 59 1.45e-05 cagtgaaaca cagataag acagctcagg chr2:198794145-198794225 52 1.45e-05 CTGTTATTAG CAGATAAG CAGGAGTGGC chr11:125423010-12542309 41 1.45e-05 gtggtggctc cagataag ggggagtgga chrX:65218094-65218174 60 1.45e-05 GAGGTGGTGG CAGATAAG CCACCCACCC chr4:25052514-25052594 26 1.45e-05 CTGTTAGGGT CAGATAAG TCCTGGTTAG chr9:125209239-125209319 52 1.45e-05 cggtaaaaca cagataag acagcttggg chr20:23113758-23113838 73 1.45e-05 AGTGTGCCGA CAGATAAG chr11:5186199-5186279 32 2.97e-05 tcggggtgca gagataag aggttggggt chr1:61514693-61514773 4 2.97e-05 GAG GAGATAAG CTAGTTATCA chr14:31291375-31291455 22 2.97e-05 tctgttccca gagataag attccctagc chr20:17906256-17906336 31 2.97e-05 GCTGTCGGAG GAGATAAG TAGATTATCT chr17:60311538-60311618 24 2.97e-05 ctgggcaaca gagataag accctatctc chr6:16263865-16263945 24 2.97e-05 atggggtgca gagataag aggtcagggc chr4:129566589-129566669 41 2.97e-05 ctgggacaca gagataag aggtcggggc chr1:35602548-35602628 24 2.97e-05 ttggggcaaa gagataag aggttggggc chr14:88491085-88491165 71 2.97e-05 ctttgcagtt gagataag ag chr4:95309280-95309360 24 2.97e-05 tcagggtgca gagataag aggttggggt chr3:152949165-152949245 27 2.97e-05 ttggggcaca gagataag aggttggggc chr9:102907628-102907708 3 2.97e-05 ca gagataag aggttggggc chr3:141567992-141568072 65 4.41e-05 TAGGCAGAAG CTGATAag gagaagca chr16:11196068-11196148 30 4.41e-05 CACAGCTGTG CTGATAAG ATTGCGTTTC chrX:119468573-119468653 23 4.41e-05 tctgctccta ctgataag gtcccctagc chr14:35122457-35122537 51 4.41e-05 ctttgcatta ctgataag ccctctatca chr17:549357-549437 27 4.41e-05 TGGCCTCTGC CTGATAAG GGTCTTATCT chrX:102356735-102356815 22 7.29e-05 tgggtacact aagataag gaagctaaaa chr11:12171498-12171578 7 7.29e-05 GGCCTC aagataag gccccataag chr7:43026528-43026608 21 7.29e-05 TGTGGAAAAA AAGATAAG ACTGGTGAGA chr5:131987933-131988013 40 7.29e-05 ctgggaggcc aagataag aggatcactt chr1:25739903-25739983 67 7.29e-05 GTGTTCAGGG GTGATAAG AAGTGG chr10:5024331-5024411 40 7.29e-05 TGTGTGTGCT GTGATAAG GAATGCTGAA chr6:28514944-28515024 13 7.29e-05 tctgcacagc aagataag taatcagcag chr19:516748-516828 71 8.66e-05 ttggagagta tagataag gt chr7:104607695-104607775 18 8.66e-05 GTGGGCTGAG TAGATAAG GCAAGCTGGG chr19:21785809-21785889 48 9.98e-05 ggtcactaga cagataaa ctcaagtcgt chr9:4862945-4863025 61 9.98e-05 GTTTTTTAGG CAGATAAA CCTGTGAACT chr9:140044931-140045011 27 9.98e-05 AGTCTCCGCC CAGATAAA AGCCCCGCCC chr10:29295066-29295146 45 1.14e-04 GTGGAAATAA GAGATAAA CGCATGTAGA chr19:4247672-4247752 53 1.27e-04 tctggtcatg cagataac ctctgcctta chr1:5946022-5946102 61 1.58e-04 ATGACAATTG GAGATAAC ATATAATGGA chr7:75943706-75943786 73 1.58e-04 CTCCCAGGCC CAGATAGG chr22:37948841-37948921 31 1.58e-04 CTGGGTGACA CAGATAGG GACGAAGAGC chr16:15615895-15615975 41 2.17e-04 ATCTGGGTTT CAGATAAT TAAGTATCTT chr15:56612693-56612773 50 2.17e-04 ATGCATGAGA GAGATAGG ACTCACCCTG chr19:1490729-1490809 18 2.17e-04 CCCGCCTCCT CCGATAAG CCTCGCCCCG chr1:25611742-25611822 67 2.17e-04 atttttagta gagatagg gtttct chr11:107885883-10788596 47 2.30e-04 tggcttattt ttgataag atagtgaggg chr4:1884780-1884860 11 2.30e-04 tggagtaaaa ttgataag ttgtgttgtt chr17:37617609-37617689 30 2.30e-04 CTCGCGTTGT TTGATAAG CAGGGGAATG chr8:20809653-20809733 7 2.73e-04 GAGGAT CTGATAAA TTCATCTATA chr12:116823781-11682386 40 2.73e-04 TGGGTCATTG GCGATAAG GGCAGGTTGG chr9:138842307-138842387 21 2.73e-04 gaaaaaatca gcgataag cctataagaa chr8:126954478-126954558 61 2.73e-04 ctgattagct gagataat ctctgctctc chrX:40032082-40032162 32 2.73e-04 CTGACACTGG GCGATAAG GAGTTCCTCG chr3:5468212-5468292 46 2.99e-04 AAAGGAGCGC GTGATAAA ATGCTATGGA chr5:131332575-131332655 55 2.99e-04 ctgagaatga aagataaa gatgaaaggg chr7:7082273-7082353 5 3.12e-04 ccta tagataaa accccatctc chr13:27557249-27557329 42 3.25e-04 TTGCAGCTCA CTGATAAC CAGAAATGAG chr3:125152066-125152146 29 3.25e-04 ttgtgcagtg ctgataac accaacgttg chr22:40316291-40316371 70 3.25e-04 AATGTGTGAA CTGATAAC ACA chr4:144826750-144826830 39 3.69e-04 CCATCATCAG CTGATAGG CAGGGGAGGC chr6:52168905-52168985 38 3.82e-04 ctggaatcta tagataac ataaccagtt chr6:119863385-119863465 70 4.71e-04 GTGCTGTTGT CTGATAAT GGT chr13:109421983-10942206 39 4.71e-04 tctggaataa cagattag aaagacagtt chr3:126630368-126630448 8 4.71e-04 GCTTAGG CAGATTAG ATGAGTGGGG chr13:44972132-44972212 2 4.71e-04 T CAGAAAAG GCATGTACAA chr1:70005893-70005973 50 4.71e-04 GGTGAGGACT AAGATAGG GTCGAGTTAT chr12:29534127-29534207 34 4.71e-04 CTGAAAACGT CAGAAAAG AGACAATGTA chr7:92515504-92515584 71 5.88e-04 tctgcaaaca aagataat ct chr2:191049369-191049449 8 5.88e-04 CAATAAG GAGATACG GCTTCCCCTA chr9:136159297-136159377 43 5.88e-04 gtgacagcct gagatacg gcctcgaggg chr2:192701665-192701745 53 6.56e-04 GGCAGTGACT GAGATAGA CCAGGAAGCT chr12:123237304-12323738 51 6.83e-04 CCGGAATCTC GCGATAAA GGCTCATTGT chr22:32022697-32022777 49 6.98e-04 TTGGCCTGCA CAGATAGC GGAAGGAAGA -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif SAGATAAG MEME-1 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr8:37949384-37949464 1.5e-05 54_[+1]_18 chr16:25783263-25783343 1.5e-05 68_[+1]_4 chr19:52051129-52051209 1.5e-05 58_[+1]_14 chr2:198794145-198794225 1.5e-05 51_[+1]_21 chr11:125423010-12542309 1.5e-05 40_[+1]_32 chrX:65218094-65218174 1.5e-05 59_[+1]_13 chr4:25052514-25052594 1.5e-05 25_[+1]_47 chr9:125209239-125209319 1.5e-05 51_[+1]_21 chr20:23113758-23113838 1.5e-05 72_[+1] chr11:5186199-5186279 3e-05 31_[+1]_41 chr1:61514693-61514773 3e-05 3_[+1]_69 chr14:31291375-31291455 3e-05 21_[+1]_51 chr20:17906256-17906336 3e-05 30_[+1]_42 chr17:60311538-60311618 3e-05 23_[+1]_49 chr6:16263865-16263945 3e-05 23_[+1]_49 chr4:129566589-129566669 3e-05 40_[+1]_32 chr1:35602548-35602628 3e-05 23_[+1]_49 chr14:88491085-88491165 3e-05 70_[+1]_2 chr4:95309280-95309360 3e-05 23_[+1]_49 chr3:152949165-152949245 3e-05 26_[+1]_46 chr9:102907628-102907708 3e-05 2_[+1]_70 chr3:141567992-141568072 4.4e-05 64_[+1]_8 chr16:11196068-11196148 4.4e-05 29_[+1]_43 chrX:119468573-119468653 4.4e-05 22_[+1]_50 chr14:35122457-35122537 4.4e-05 50_[+1]_22 chr17:549357-549437 4.4e-05 26_[+1]_46 chrX:102356735-102356815 7.3e-05 21_[+1]_51 chr11:12171498-12171578 7.3e-05 6_[+1]_66 chr7:43026528-43026608 7.3e-05 20_[+1]_52 chr5:131987933-131988013 7.3e-05 39_[+1]_33 chr1:25739903-25739983 7.3e-05 66_[+1]_6 chr10:5024331-5024411 7.3e-05 39_[+1]_33 chr6:28514944-28515024 7.3e-05 12_[+1]_60 chr19:516748-516828 8.7e-05 70_[+1]_2 chr7:104607695-104607775 8.7e-05 17_[+1]_55 chr19:21785809-21785889 0.0001 47_[+1]_25 chr9:4862945-4863025 0.0001 60_[+1]_12 chr9:140044931-140045011 0.0001 26_[+1]_46 chr10:29295066-29295146 0.00011 44_[+1]_28 chr19:4247672-4247752 0.00013 52_[+1]_20 chr1:5946022-5946102 0.00016 60_[+1]_12 chr7:75943706-75943786 0.00016 72_[+1] chr22:37948841-37948921 0.00016 30_[+1]_42 chr16:15615895-15615975 0.00022 40_[+1]_32 chr15:56612693-56612773 0.00022 49_[+1]_23 chr19:1490729-1490809 0.00022 17_[+1]_55 chr1:25611742-25611822 0.00022 66_[+1]_6 chr11:107885883-10788596 0.00023 46_[+1]_26 chr4:1884780-1884860 0.00023 10_[+1]_62 chr17:37617609-37617689 0.00023 29_[+1]_43 chr8:20809653-20809733 0.00027 6_[+1]_66 chr12:116823781-11682386 0.00027 39_[+1]_33 chr9:138842307-138842387 0.00027 20_[+1]_52 chr8:126954478-126954558 0.00027 60_[+1]_12 chrX:40032082-40032162 0.00027 31_[+1]_41 chr3:5468212-5468292 0.0003 45_[+1]_27 chr5:131332575-131332655 0.0003 54_[+1]_18 chr7:7082273-7082353 0.00031 4_[+1]_68 chr13:27557249-27557329 0.00033 41_[+1]_31 chr3:125152066-125152146 0.00033 28_[+1]_44 chr22:40316291-40316371 0.00033 69_[+1]_3 chr4:144826750-144826830 0.00037 38_[+1]_34 chr6:52168905-52168985 0.00038 37_[+1]_35 chr6:119863385-119863465 0.00047 69_[+1]_3 chr13:109421983-10942206 0.00047 38_[+1]_34 chr3:126630368-126630448 0.00047 7_[+1]_65 chr13:44972132-44972212 0.00047 1_[+1]_71 chr1:70005893-70005973 0.00047 49_[+1]_23 chr12:29534127-29534207 0.00047 33_[+1]_39 chr7:92515504-92515584 0.00059 70_[+1]_2 chr2:191049369-191049449 0.00059 7_[+1]_65 chr9:136159297-136159377 0.00059 42_[+1]_30 chr2:192701665-192701745 0.00066 52_[+1]_20 chr12:123237304-12323738 0.00068 50_[+1]_22 chr22:32022697-32022777 0.0007 48_[+1]_24 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif SAGATAAG MEME-1 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF SAGATAAG width=8 seqs=75 chr8:37949384-37949464 ( 55) CAGATAAG 1 chr16:25783263-25783343 ( 69) CAGATAAG 1 chr19:52051129-52051209 ( 59) CAGATAAG 1 chr2:198794145-198794225 ( 52) CAGATAAG 1 chr11:125423010-12542309 ( 41) CAGATAAG 1 chrX:65218094-65218174 ( 60) CAGATAAG 1 chr4:25052514-25052594 ( 26) CAGATAAG 1 chr9:125209239-125209319 ( 52) CAGATAAG 1 chr20:23113758-23113838 ( 73) CAGATAAG 1 chr11:5186199-5186279 ( 32) GAGATAAG 1 chr1:61514693-61514773 ( 4) GAGATAAG 1 chr14:31291375-31291455 ( 22) GAGATAAG 1 chr20:17906256-17906336 ( 31) GAGATAAG 1 chr17:60311538-60311618 ( 24) GAGATAAG 1 chr6:16263865-16263945 ( 24) GAGATAAG 1 chr4:129566589-129566669 ( 41) GAGATAAG 1 chr1:35602548-35602628 ( 24) GAGATAAG 1 chr14:88491085-88491165 ( 71) GAGATAAG 1 chr4:95309280-95309360 ( 24) GAGATAAG 1 chr3:152949165-152949245 ( 27) GAGATAAG 1 chr9:102907628-102907708 ( 3) GAGATAAG 1 chr3:141567992-141568072 ( 65) CTGATAAG 1 chr16:11196068-11196148 ( 30) CTGATAAG 1 chrX:119468573-119468653 ( 23) CTGATAAG 1 chr14:35122457-35122537 ( 51) CTGATAAG 1 chr17:549357-549437 ( 27) CTGATAAG 1 chrX:102356735-102356815 ( 22) AAGATAAG 1 chr11:12171498-12171578 ( 7) AAGATAAG 1 chr7:43026528-43026608 ( 21) AAGATAAG 1 chr5:131987933-131988013 ( 40) AAGATAAG 1 chr1:25739903-25739983 ( 67) GTGATAAG 1 chr10:5024331-5024411 ( 40) GTGATAAG 1 chr6:28514944-28515024 ( 13) AAGATAAG 1 chr19:516748-516828 ( 71) TAGATAAG 1 chr7:104607695-104607775 ( 18) TAGATAAG 1 chr19:21785809-21785889 ( 48) CAGATAAA 1 chr9:4862945-4863025 ( 61) CAGATAAA 1 chr9:140044931-140045011 ( 27) CAGATAAA 1 chr10:29295066-29295146 ( 45) GAGATAAA 1 chr19:4247672-4247752 ( 53) CAGATAAC 1 chr1:5946022-5946102 ( 61) GAGATAAC 1 chr7:75943706-75943786 ( 73) CAGATAGG 1 chr22:37948841-37948921 ( 31) CAGATAGG 1 chr16:15615895-15615975 ( 41) CAGATAAT 1 chr15:56612693-56612773 ( 50) GAGATAGG 1 chr19:1490729-1490809 ( 18) CCGATAAG 1 chr1:25611742-25611822 ( 67) GAGATAGG 1 chr11:107885883-10788596 ( 47) TTGATAAG 1 chr4:1884780-1884860 ( 11) TTGATAAG 1 chr17:37617609-37617689 ( 30) TTGATAAG 1 chr8:20809653-20809733 ( 7) CTGATAAA 1 chr12:116823781-11682386 ( 40) GCGATAAG 1 chr9:138842307-138842387 ( 21) GCGATAAG 1 chr8:126954478-126954558 ( 61) GAGATAAT 1 chrX:40032082-40032162 ( 32) GCGATAAG 1 chr3:5468212-5468292 ( 46) GTGATAAA 1 chr5:131332575-131332655 ( 55) AAGATAAA 1 chr7:7082273-7082353 ( 5) TAGATAAA 1 chr13:27557249-27557329 ( 42) CTGATAAC 1 chr3:125152066-125152146 ( 29) CTGATAAC 1 chr22:40316291-40316371 ( 70) CTGATAAC 1 chr4:144826750-144826830 ( 39) CTGATAGG 1 chr6:52168905-52168985 ( 38) TAGATAAC 1 chr6:119863385-119863465 ( 70) CTGATAAT 1 chr13:109421983-10942206 ( 39) CAGATTAG 1 chr3:126630368-126630448 ( 8) CAGATTAG 1 chr13:44972132-44972212 ( 2) CAGAAAAG 1 chr1:70005893-70005973 ( 50) AAGATAGG 1 chr12:29534127-29534207 ( 34) CAGAAAAG 1 chr7:92515504-92515584 ( 71) AAGATAAT 1 chr2:191049369-191049449 ( 8) GAGATACG 1 chr9:136159297-136159377 ( 43) GAGATACG 1 chr2:192701665-192701745 ( 53) GAGATAGA 1 chr12:123237304-12323738 ( 51) GCGATAAA 1 chr22:32022697-32022777 ( 49) CAGATAGC 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif SAGATAAG MEME-1 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 8.10161 E= 7.3e-024 -117 79 44 -136 155 -193 -1287 -8 -1287 -1287 191 -1287 206 -1287 -1287 -1287 -317 -1287 -1287 203 202 -1287 -1287 -316 185 -325 -132 -1287 -85 -145 144 -216 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif SAGATAAG MEME-1 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 75 E= 7.3e-024 0.106667 0.440000 0.360000 0.093333 0.706667 0.066667 0.000000 0.226667 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.026667 0.000000 0.000000 0.973333 0.973333 0.000000 0.000000 0.026667 0.866667 0.026667 0.106667 0.000000 0.133333 0.093333 0.720000 0.053333 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif SAGATAAG MEME-1 regular expression -------------------------------------------------------------------------------- [CG][AT]GATAAG -------------------------------------------------------------------------------- Time 5.00 secs. ******************************************************************************** ******************************************************************************** MOTIF CTTATCTY MEME-2 width = 8 sites = 58 llr = 459 E-value = 1.4e-016 ******************************************************************************** -------------------------------------------------------------------------------- Motif CTTATCTY MEME-2 Description -------------------------------------------------------------------------------- Simplified A 1::a::21 pos.-specific C 62:::a:4 probability G 2::::::1 matrix T 18a:a:83 bits 2.1 *** 1.9 **** 1.7 **** 1.4 ****** Relative 1.2 ****** Entropy 1.0 ****** (11.4 bits) 0.8 ****** 0.6 ****** 0.4 ******* 0.2 ******** 0.0 -------- Multilevel CTTATCTC consensus T sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTTATCTY MEME-2 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr1:5946022-5946102 20 1.30e-05 TTCCTATGAG CTTATCTC TCTCTTGCAG chr9:101694447-101694527 33 1.30e-05 CCGTCTCTGG CTTATCTC AAGGACACAT chr16:20685563-20685643 6 1.30e-05 tgagc cttatctc tccctttccc chr9:35004446-35004526 28 1.30e-05 gccccgacct cttatctc tgcgccccga chr1:211395910-211395990 53 1.30e-05 atgccttcct cttatctc aactgcaaag chr11:68391362-68391442 46 1.30e-05 gccccgacct cttatctc tgcaccccaa chr3:171164805-171164885 1 1.30e-05 . cttatctc tactaaaaat chr6:142337978-142338058 73 1.30e-05 gccccaacct cttatctc chr17:11876215-11876295 32 1.30e-05 accccaacct cttatctc tgcgccccag chr13:25968978-25969058 55 2.53e-05 ctaaagcagc cttatctt ccattaattt chr17:65852270-65852350 64 2.53e-05 ttaagatttc cttatctt ggtcgtcca chr5:39194731-39194811 30 2.53e-05 TGTTTGCTGG CTTATCTT AGAAGAGCAG chr12:92798821-92798901 53 2.53e-05 CTTCTTCTGC CTTATCTT TGGTCTCCTT chr3:49398931-49399011 17 2.53e-05 TCAAGATTTC CTTATCTT TCAGTTGCCA chr19:52051129-52051209 13 2.53e-05 aaggaaatca cttatctt ctgacaacaa chr2:25479546-25479626 28 2.53e-05 ccttctgtcc cttatctt tcccttctgt chr9:125209239-125209319 6 2.53e-05 aatca cttatctt ctaacaataa chr17:549357-549437 38 2.53e-05 TGATAAGGGT CTTATCTT TTCTAATTCA chr9:73100399-73100479 28 3.89e-05 CTCCGCCAGG CTTATCTG TGCAAAGCAG chr22:36764702-36764782 23 5.25e-05 GTGGAGGAGT GTTATCTC CCCACCCTTA chr8:20809653-20809733 58 8.99e-05 CCTTTAACGT GTTATCTT TCCAAGCAGA chr4:144826750-144826830 1 8.99e-05 . GTTATCTT CCAGGCCCAC chr14:20645713-20645793 36 8.99e-05 gcaactcatg cttatcta tcttgtgacc chr13:44972132-44972212 43 8.99e-05 CCGATTAGTC ATTATCTC CTCTGTGGTC chr9:35728596-35728676 2 8.99e-05 C ATTATCTC AATCACACAG chr3:186589330-186589410 8 1.03e-04 TTGTCAG CTTATCAC TGAGTCTGGC chr3:195805977-195806057 34 1.03e-04 TTACAAAAAG CTTATCAC TACCACTCCA chrX:119468573-119468653 53 1.03e-04 aaaagctctc cttatcac agggatcaga chr1:25606332-25606412 16 1.03e-04 ACATCCACTT CTTATCAC CCCTGAACAC chr2:145199439-145199519 3 1.41e-04 AC ATTATCTT ACAGAGCAGA chr7:77502870-77502950 57 1.41e-04 cagcacaagg tttatctc ttcagacaaa chr4:81100942-81101022 26 1.41e-04 cagtgcagga tttatctc ctcagacaaa chr17:60311538-60311618 34 1.41e-04 gagataagac cctatctc aaaaaaaaaa chr3:32115890-32115970 27 1.41e-04 tcctttactc tttatctc cagaacccag chr5:148018813-148018893 41 1.53e-04 atccaaattc cttatcat agctaaccag chrX:11479838-11479918 35 1.77e-04 AAACCACATT CCTATCTT GTAGGCTAAG chr4:68418035-68418115 48 1.77e-04 ttttagcttc cctatctt agtgcacctg chr20:33780336-33780416 30 1.77e-04 ttttagcttc cctatctt agtgcacctg chrX:151345707-151345787 39 1.77e-04 ggcagaatgt tttatctt cccatgaaca chr5:180209025-180209105 8 1.92e-04 cgattat gttatctg tagattccag chr1:65696954-65697034 23 2.05e-04 AATAAATGCC ATTATCTG TATGTTTCAG chr20:17906256-17906336 42 2.05e-04 AGATAAGTAG ATTATCTG TCAGCCCAAC chr19:7894851-7894931 6 2.31e-04 TTGGT CTTATCAG GTGTTGATCA chr6:27741819-27741899 31 2.31e-04 cactggttat gttatcta tagtttccag chr8:38068325-38068405 6 2.31e-04 ACAGG CTTATCAG AAACCTACCA chr14:102144480-10214456 34 2.31e-04 GAAGAAATAT GTTATCTA CATTGAACAG chr16:15615895-15615975 28 2.72e-04 GCTCCTGCTG TTTATCTG GGTTTCAGAT chr5:131649930-131650010 3 2.72e-04 GG CCTATCTG GCCTCACCCT chr5:1067938-1068018 19 2.72e-04 CGGGGACCCT GTTATCAC AAGTCAGCAC chr8:130705177-130705257 26 2.98e-04 CAGAAGCTTT GCTATCTC TTAAGGGACC chr1:15110688-15110768 35 2.98e-04 acccaccctg attatcta ggacagactc chr6:44355224-44355304 17 2.98e-04 CGCTACCGCC GCTATCTC GCGAGAGCCG chr8:37939595-37939675 9 3.36e-04 aacatacg cttatcaa ccttgtaact chr4:80131432-80131512 4 3.36e-04 tac attatcac aaggtgggag chr12:4262871-4262951 61 3.87e-04 TCAGAACTTT GCTATCTT GTCCTCAGCT chr2:17699738-17699818 59 4.39e-04 TGGCCTTAGC CTAATCTC AGGGTTTgcc chr16:70470017-70470097 4 4.64e-04 gac tctatctc aaaaaaaaaa chr14:69186595-69186675 21 5.01e-04 ttgaagtgca ctaatctt acattagcag -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTTATCTY MEME-2 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr1:5946022-5946102 1.3e-05 19_[+2]_53 chr9:101694447-101694527 1.3e-05 32_[+2]_40 chr16:20685563-20685643 1.3e-05 5_[+2]_67 chr9:35004446-35004526 1.3e-05 27_[+2]_45 chr1:211395910-211395990 1.3e-05 52_[+2]_20 chr11:68391362-68391442 1.3e-05 45_[+2]_27 chr3:171164805-171164885 1.3e-05 [+2]_72 chr6:142337978-142338058 1.3e-05 72_[+2] chr17:11876215-11876295 1.3e-05 31_[+2]_41 chr13:25968978-25969058 2.5e-05 54_[+2]_18 chr17:65852270-65852350 2.5e-05 63_[+2]_9 chr5:39194731-39194811 2.5e-05 29_[+2]_43 chr12:92798821-92798901 2.5e-05 52_[+2]_20 chr3:49398931-49399011 2.5e-05 16_[+2]_56 chr19:52051129-52051209 2.5e-05 12_[+2]_60 chr2:25479546-25479626 2.5e-05 27_[+2]_45 chr9:125209239-125209319 2.5e-05 5_[+2]_67 chr17:549357-549437 2.5e-05 37_[+2]_35 chr9:73100399-73100479 3.9e-05 27_[+2]_45 chr22:36764702-36764782 5.2e-05 22_[+2]_50 chr8:20809653-20809733 9e-05 57_[+2]_15 chr4:144826750-144826830 9e-05 [+2]_72 chr14:20645713-20645793 9e-05 35_[+2]_37 chr13:44972132-44972212 9e-05 42_[+2]_30 chr9:35728596-35728676 9e-05 1_[+2]_71 chr3:186589330-186589410 0.0001 7_[+2]_65 chr3:195805977-195806057 0.0001 33_[+2]_39 chrX:119468573-119468653 0.0001 52_[+2]_20 chr1:25606332-25606412 0.0001 15_[+2]_57 chr2:145199439-145199519 0.00014 2_[+2]_70 chr7:77502870-77502950 0.00014 56_[+2]_16 chr4:81100942-81101022 0.00014 25_[+2]_47 chr17:60311538-60311618 0.00014 33_[+2]_39 chr3:32115890-32115970 0.00014 26_[+2]_46 chr5:148018813-148018893 0.00015 40_[+2]_32 chrX:11479838-11479918 0.00018 34_[+2]_38 chr4:68418035-68418115 0.00018 47_[+2]_25 chr20:33780336-33780416 0.00018 29_[+2]_43 chrX:151345707-151345787 0.00018 38_[+2]_34 chr5:180209025-180209105 0.00019 7_[+2]_65 chr1:65696954-65697034 0.0002 22_[+2]_50 chr20:17906256-17906336 0.0002 41_[+2]_31 chr19:7894851-7894931 0.00023 5_[+2]_67 chr6:27741819-27741899 0.00023 30_[+2]_42 chr8:38068325-38068405 0.00023 5_[+2]_67 chr14:102144480-10214456 0.00023 33_[+2]_39 chr16:15615895-15615975 0.00027 27_[+2]_45 chr5:131649930-131650010 0.00027 2_[+2]_70 chr5:1067938-1068018 0.00027 18_[+2]_54 chr8:130705177-130705257 0.0003 25_[+2]_47 chr1:15110688-15110768 0.0003 34_[+2]_38 chr6:44355224-44355304 0.0003 16_[+2]_56 chr8:37939595-37939675 0.00034 8_[+2]_64 chr4:80131432-80131512 0.00034 3_[+2]_69 chr12:4262871-4262951 0.00039 60_[+2]_12 chr2:17699738-17699818 0.00044 58_[+2]_14 chr16:70470017-70470097 0.00046 3_[+2]_69 chr14:69186595-69186675 0.0005 20_[+2]_52 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTTATCTY MEME-2 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF CTTATCTY width=8 seqs=58 chr1:5946022-5946102 ( 20) CTTATCTC 1 chr9:101694447-101694527 ( 33) CTTATCTC 1 chr16:20685563-20685643 ( 6) CTTATCTC 1 chr9:35004446-35004526 ( 28) CTTATCTC 1 chr1:211395910-211395990 ( 53) CTTATCTC 1 chr11:68391362-68391442 ( 46) CTTATCTC 1 chr3:171164805-171164885 ( 1) CTTATCTC 1 chr6:142337978-142338058 ( 73) CTTATCTC 1 chr17:11876215-11876295 ( 32) CTTATCTC 1 chr13:25968978-25969058 ( 55) CTTATCTT 1 chr17:65852270-65852350 ( 64) CTTATCTT 1 chr5:39194731-39194811 ( 30) CTTATCTT 1 chr12:92798821-92798901 ( 53) CTTATCTT 1 chr3:49398931-49399011 ( 17) CTTATCTT 1 chr19:52051129-52051209 ( 13) CTTATCTT 1 chr2:25479546-25479626 ( 28) CTTATCTT 1 chr9:125209239-125209319 ( 6) CTTATCTT 1 chr17:549357-549437 ( 38) CTTATCTT 1 chr9:73100399-73100479 ( 28) CTTATCTG 1 chr22:36764702-36764782 ( 23) GTTATCTC 1 chr8:20809653-20809733 ( 58) GTTATCTT 1 chr4:144826750-144826830 ( 1) GTTATCTT 1 chr14:20645713-20645793 ( 36) CTTATCTA 1 chr13:44972132-44972212 ( 43) ATTATCTC 1 chr9:35728596-35728676 ( 2) ATTATCTC 1 chr3:186589330-186589410 ( 8) CTTATCAC 1 chr3:195805977-195806057 ( 34) CTTATCAC 1 chrX:119468573-119468653 ( 53) CTTATCAC 1 chr1:25606332-25606412 ( 16) CTTATCAC 1 chr2:145199439-145199519 ( 3) ATTATCTT 1 chr7:77502870-77502950 ( 57) TTTATCTC 1 chr4:81100942-81101022 ( 26) TTTATCTC 1 chr17:60311538-60311618 ( 34) CCTATCTC 1 chr3:32115890-32115970 ( 27) TTTATCTC 1 chr5:148018813-148018893 ( 41) CTTATCAT 1 chrX:11479838-11479918 ( 35) CCTATCTT 1 chr4:68418035-68418115 ( 48) CCTATCTT 1 chr20:33780336-33780416 ( 30) CCTATCTT 1 chrX:151345707-151345787 ( 39) TTTATCTT 1 chr5:180209025-180209105 ( 8) GTTATCTG 1 chr1:65696954-65697034 ( 23) ATTATCTG 1 chr20:17906256-17906336 ( 42) ATTATCTG 1 chr19:7894851-7894931 ( 6) CTTATCAG 1 chr6:27741819-27741899 ( 31) GTTATCTA 1 chr8:38068325-38068405 ( 6) CTTATCAG 1 chr14:102144480-10214456 ( 34) GTTATCTA 1 chr16:15615895-15615975 ( 28) TTTATCTG 1 chr5:131649930-131650010 ( 3) CCTATCTG 1 chr5:1067938-1068018 ( 19) GTTATCAC 1 chr8:130705177-130705257 ( 26) GCTATCTC 1 chr1:15110688-15110768 ( 35) ATTATCTA 1 chr6:44355224-44355304 ( 17) GCTATCTC 1 chr8:37939595-37939675 ( 9) CTTATCAA 1 chr4:80131432-80131512 ( 4) ATTATCAC 1 chr12:4262871-4262951 ( 61) GCTATCTT 1 chr2:17699738-17699818 ( 59) CTAATCTC 1 chr16:70470017-70470097 ( 4) TCTATCTC 1 chr14:69186595-69186675 ( 21) CTAATCTT 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTTATCTY MEME-2 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 9.98426 E= 1.4e-016 -99 124 -63 -121 -1250 -71 -1250 182 -280 -1250 -1250 201 206 -1250 -1250 -1250 -1250 -1250 -1250 207 -1250 197 -1250 -1250 -48 -1250 -1250 179 -148 82 -95 46 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTTATCTY MEME-2 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 58 E= 1.4e-016 0.120690 0.603448 0.172414 0.103448 0.000000 0.155172 0.000000 0.844828 0.034483 0.000000 0.000000 0.965517 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 0.172414 0.000000 0.000000 0.827586 0.086207 0.448276 0.137931 0.327586 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTTATCTY MEME-2 regular expression -------------------------------------------------------------------------------- CTTATCT[CT] -------------------------------------------------------------------------------- Time 8.71 secs. ******************************************************************************** ******************************************************************************** MOTIF TCTCGCGA MEME-3 width = 8 sites = 22 llr = 216 E-value = 2.7e-007 ******************************************************************************** -------------------------------------------------------------------------------- Motif TCTCGCGA MEME-3 Description -------------------------------------------------------------------------------- Simplified A :::::::8 pos.-specific C :a:a:a:: probability G ::::a:a1 matrix T 9:a::::: bits 2.1 * * * 1.9 ****** 1.7 ****** 1.4 ******* Relative 1.2 ******* Entropy 1.0 ******** (14.1 bits) 0.8 ******** 0.6 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel TCTCGCGA consensus sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCTCGCGA MEME-3 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr1:27226906-27226986 60 1.62e-05 TAGAACCAAG TCTCGCGA GAACACCGCG chr17:40714081-40714161 4 1.62e-05 AAA TCTCGCGA GAATCCCGCG chr17:27717290-27717370 20 1.62e-05 AGGCGGAAAA TCTCGCGA GATCGGAGAC chr1:19923371-19923451 41 1.62e-05 CAGCGGATCA TCTCGCGA TATCTGGAGC chr14:102414492-10241457 11 1.62e-05 AGACGCCCAA TCTCGCGA GTGAGCGAGA chr15:22833365-22833445 57 1.62e-05 GAGCGCGAAC TCTCGCGA GAATGCCGCC chr12:123237304-12323738 16 1.62e-05 TCTTCCGGCT TCTCGCGA CATCCGCCCA chr1:78148349-78148429 42 1.62e-05 CCCACTCGCA TCTCGCGA GCTTCCACTA chr12:29534127-29534207 56 1.62e-05 AATGTACAGA TCTCGCGA TATTCCCTTT chr6:35995408-35995488 18 1.62e-05 ATTGTTCTCT TCTCGCGA GAACTGCTCC chr17:53046026-53046106 49 1.62e-05 GCGTGCTCCG TCTCGCGA GATCTGGGTT chr9:98637851-98637931 30 1.62e-05 AAGATTTCGT TCTCGCGA GATCCCAATG chr10:51565111-51565191 36 1.62e-05 CGAGCGGAGA TCTCGCGA GACTGTCAGA chr3:49131519-49131599 2 1.62e-05 C TCTCGCGA TAATCGGGGC chr17:4843528-4843608 26 1.62e-05 GTTGGAGCGC TCTCGCGA TAGACACAGC chr2:677400-677480 67 3.40e-05 GCTTGCTTCC TCTCGCGG TAATTT chr4:17812523-17812603 30 3.40e-05 GATTTCCCCC TCTCGCGG GAATTATTTG chr20:34330251-34330331 63 6.71e-05 CGTAGCCCAA TCTCGCGC AATGATTGCG chr17:37617609-37617689 19 6.71e-05 TGGGACCTGA TCTCGCGT TGTTTGATAA chr17:4167238-4167318 22 8.43e-05 CTGCCTGCAA CCTCGCGA GAAGTGCGCG chr15:78730331-78730411 67 1.02e-04 CTCCGCCCCC GCTCGCGA GAACAG chr12:49351266-49351346 49 1.20e-04 ACCTCCCCGA TCGCGCGA TAGCTGCGCG -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCTCGCGA MEME-3 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr1:27226906-27226986 1.6e-05 59_[+3]_13 chr17:40714081-40714161 1.6e-05 3_[+3]_69 chr17:27717290-27717370 1.6e-05 19_[+3]_53 chr1:19923371-19923451 1.6e-05 40_[+3]_32 chr14:102414492-10241457 1.6e-05 10_[+3]_62 chr15:22833365-22833445 1.6e-05 56_[+3]_16 chr12:123237304-12323738 1.6e-05 15_[+3]_57 chr1:78148349-78148429 1.6e-05 41_[+3]_31 chr12:29534127-29534207 1.6e-05 55_[+3]_17 chr6:35995408-35995488 1.6e-05 17_[+3]_55 chr17:53046026-53046106 1.6e-05 48_[+3]_24 chr9:98637851-98637931 1.6e-05 29_[+3]_43 chr10:51565111-51565191 1.6e-05 35_[+3]_37 chr3:49131519-49131599 1.6e-05 1_[+3]_71 chr17:4843528-4843608 1.6e-05 25_[+3]_47 chr2:677400-677480 3.4e-05 66_[+3]_6 chr4:17812523-17812603 3.4e-05 29_[+3]_43 chr20:34330251-34330331 6.7e-05 62_[+3]_10 chr17:37617609-37617689 6.7e-05 18_[+3]_54 chr17:4167238-4167318 8.4e-05 21_[+3]_51 chr15:78730331-78730411 0.0001 66_[+3]_6 chr12:49351266-49351346 0.00012 48_[+3]_24 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCTCGCGA MEME-3 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF TCTCGCGA width=8 seqs=22 chr1:27226906-27226986 ( 60) TCTCGCGA 1 chr17:40714081-40714161 ( 4) TCTCGCGA 1 chr17:27717290-27717370 ( 20) TCTCGCGA 1 chr1:19923371-19923451 ( 41) TCTCGCGA 1 chr14:102414492-10241457 ( 11) TCTCGCGA 1 chr15:22833365-22833445 ( 57) TCTCGCGA 1 chr12:123237304-12323738 ( 16) TCTCGCGA 1 chr1:78148349-78148429 ( 42) TCTCGCGA 1 chr12:29534127-29534207 ( 56) TCTCGCGA 1 chr6:35995408-35995488 ( 18) TCTCGCGA 1 chr17:53046026-53046106 ( 49) TCTCGCGA 1 chr9:98637851-98637931 ( 30) TCTCGCGA 1 chr10:51565111-51565191 ( 36) TCTCGCGA 1 chr3:49131519-49131599 ( 2) TCTCGCGA 1 chr17:4843528-4843608 ( 26) TCTCGCGA 1 chr2:677400-677480 ( 67) TCTCGCGG 1 chr4:17812523-17812603 ( 30) TCTCGCGG 1 chr20:34330251-34330331 ( 63) TCTCGCGC 1 chr17:37617609-37617689 ( 19) TCTCGCGT 1 chr17:4167238-4167318 ( 22) CCTCGCGA 1 chr15:78730331-78730411 ( 67) GCTCGCGA 1 chr12:49351266-49351346 ( 49) TCGCGCGA 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCTCGCGA MEME-3 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 10.0499 E= 2.7e-007 -1110 -248 -255 193 -1110 197 -1110 -1110 -1110 -1110 -255 200 -1110 197 -1110 -1110 -1110 -1110 191 -1110 -1110 197 -1110 -1110 -1110 -1110 191 -1110 177 -248 -155 -239 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCTCGCGA MEME-3 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 22 E= 2.7e-007 0.000000 0.045455 0.045455 0.909091 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.045455 0.954545 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.818182 0.045455 0.090909 0.045455 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCTCGCGA MEME-3 regular expression -------------------------------------------------------------------------------- TCTCGCGA -------------------------------------------------------------------------------- Time 12.31 secs. ******************************************************************************** ******************************************************************************** MOTIF RRGTGSAG MEME-4 width = 8 sites = 52 llr = 391 E-value = 7.6e+000 ******************************************************************************** -------------------------------------------------------------------------------- Motif RRGTGSAG MEME-4 Description -------------------------------------------------------------------------------- Simplified A 43:3::7: pos.-specific C :::::6:: probability G 67a:a4:a matrix T :::7::3: bits 2.1 1.9 * * 1.7 * * * 1.4 * * * Relative 1.2 *** ** Entropy 1.0 ******** (10.9 bits) 0.8 ******** 0.6 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel GGGTGCAG consensus AA A GT sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif RRGTGSAG MEME-4 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr1:201528951-201529031 13 1.96e-05 CGCCACCAGA GGGTGCAG TTGCCCAGCA chr11:5186199-5186279 46 1.96e-05 taagaggttg gggtgcag aaataaggga chr5:131651365-131651445 27 1.96e-05 GTAAGACCCT GGGTGCAG CAGCCTCGCT chr6:16263865-16263945 59 1.96e-05 taagggattg gggtgcag agataagagg chr7:7082273-7082353 58 1.96e-05 gggcggctgt gggtgcag cttcatcaga chr1:35602548-35602628 59 1.96e-05 taagggattg gggtgcag agataagggg chr4:95309280-95309360 59 1.96e-05 taagggatcg gggtgcag agataagggg chr9:102907628-102907708 37 1.96e-05 ataagggatg gggtgcag agataagaag chr12:133047863-13304794 63 3.73e-05 cagggaacaa aggtgcag ttatgagatt chr8:130594485-130594565 17 3.73e-05 TCAATGCTCA AGGTGCAG AGGGAGATTG chr14:102144480-10214456 50 3.73e-05 TACATTGAAC AGGTGCAG CGGGAAAAGG chr16:517816-517896 6 3.73e-05 GGAGG AGGTGCAG GGGCCTCAGG chr16:517616-517696 52 3.73e-05 CTCAGGGAGG AGGTGCAG GGGCGTCAGG chr7:65580469-65580549 3 5.77e-05 TG GGGTGGAG AAGGGAAGGA chr20:23113758-23113838 31 5.77e-05 GGAAGGTCAT GGGTGGAG TGAGGTCATG chr10:51565312-51565392 3 5.77e-05 CC GGGTGGAG GCTCGATGAC chr19:1123170-1123250 40 5.77e-05 AGGAATGCCT GGGTGGAG GAGTGGTCAG chr22:36764702-36764782 11 9.39e-05 CAGTGCTGGG AGGTGGAG GAGTGTTATC chr3:16977885-16977965 26 9.39e-05 TGCAAGAGTG AGGTGGAG TTTGGTGGCT chr18:968420-968500 62 9.39e-05 gcccaggctg gagtgcag tggcgcgata chr1:25606332-25606412 72 9.39e-05 CAGCTGATGT GAGTGCAG A chr12:132166853-13216693 59 9.39e-05 GGCGGGAGGA AGGTGGAG CAACCCCATG chr2:191049369-191049449 69 1.29e-04 ACAGGGGAAA GGGTGCTG GGTG chr2:38871051-38871131 17 1.85e-04 AACAGGTACA GAGTGGAG GATGTGACAG chr13:25968978-25969058 19 1.85e-04 ccagagcagt gagtggag cctgcatgac chr6:119863385-119863465 58 1.85e-04 ATTCTCTTGA AGGTGCTG TTGTCTGATA chr11:71639559-71639639 49 1.85e-04 GCAAGATGGC AGGTGCTG CAGCCAGGAA chr22:37948841-37948921 13 2.40e-04 CATCACCTCG AGGAGCAG CTGGGTGACA chr19:47931506-47931586 49 2.40e-04 CGGGCGTAGC AAGTGGAG GAGCTTGGCT chrX:65218094-65218174 51 2.96e-04 CCTGGGGTAG AGGTGGTG GCAGATAAGC chr2:242824077-242824157 33 2.96e-04 CTTCCTGTGC AGGTGGTG GTGCCCTCTG chr17:4843528-4843608 71 2.96e-04 GGGACGGGAG AGGTGGTG AG chr16:89359965-89360045 20 2.96e-04 gggctgcgga gggaggag ctggggcaga chr11:107885883-10788596 3 3.49e-04 ca aagtgctg ggattacagg chr20:46012907-46012987 70 3.49e-04 TGGCTCCAGA GAGAGCAG CGT chr1:70005893-70005973 33 3.49e-04 TCCAGACCTC AAGTGCTG GTGAGGACTA chr2:43154850-43154930 72 4.03e-04 GGAGGGGGTG GGGAGCTG T chr17:27717290-27717370 62 4.03e-04 TGGAGGAGGG GAGTGGTG TCGGGTAAAG chr5:39194731-39194811 40 4.03e-04 CTTATCTTAG AAGAGCAG AAGAAAGAAG chr14:55221585-55221665 57 4.03e-04 TCCTGCAATG GGGAGCTG GGGACGTGCA chr19:52051129-52051209 40 4.03e-04 agcagccgga aagagcag acagtgaaac chr22:23624100-23624180 16 4.03e-04 CTGCTGGAGA GGGAGCTG CGTTTCTTGA chr10:5024331-5024411 24 4.03e-04 ACAGGACAGG GAGTGGTG TGTGTGCTGT chr9:125209239-125209319 33 4.03e-04 agcagccaga aagagcag acggtaaaac chr6:53224467-53224547 3 4.56e-04 GG GAGAGGAG GGTTGTGCGG chr8:93107702-93107782 25 4.56e-04 GCGCAGGAGG GAGAGGAG AGAAGCCAAC chr15:56612693-56612773 5 4.56e-04 gata gagaggag aaagagagag chr8:37939595-37939675 41 4.93e-04 agctgcgcta gggaggtg aagcaggaac chr11:125423010-12542309 11 5.46e-04 gtagagatgg aagagctg gtggtgtggt chr10:51565111-51565191 62 5.64e-04 GACGTATGGC GAGAGGTG TGGGAGGAAG chr2:198794145-198794225 34 5.99e-04 AGTTGGAAGT GGCTGCAG CTGTTATTAG chr3:14162496-14162576 46 6.16e-04 atctttctgc agctgcag gcatatcccc -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif RRGTGSAG MEME-4 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr1:201528951-201529031 2e-05 12_[+4]_60 chr11:5186199-5186279 2e-05 45_[+4]_27 chr5:131651365-131651445 2e-05 26_[+4]_46 chr6:16263865-16263945 2e-05 58_[+4]_14 chr7:7082273-7082353 2e-05 57_[+4]_15 chr1:35602548-35602628 2e-05 58_[+4]_14 chr4:95309280-95309360 2e-05 58_[+4]_14 chr9:102907628-102907708 2e-05 36_[+4]_36 chr12:133047863-13304794 3.7e-05 62_[+4]_10 chr8:130594485-130594565 3.7e-05 16_[+4]_56 chr14:102144480-10214456 3.7e-05 49_[+4]_23 chr16:517816-517896 3.7e-05 5_[+4]_67 chr16:517616-517696 3.7e-05 51_[+4]_21 chr7:65580469-65580549 5.8e-05 2_[+4]_70 chr20:23113758-23113838 5.8e-05 30_[+4]_42 chr10:51565312-51565392 5.8e-05 2_[+4]_70 chr19:1123170-1123250 5.8e-05 39_[+4]_33 chr22:36764702-36764782 9.4e-05 10_[+4]_62 chr3:16977885-16977965 9.4e-05 25_[+4]_47 chr18:968420-968500 9.4e-05 61_[+4]_11 chr1:25606332-25606412 9.4e-05 71_[+4]_1 chr12:132166853-13216693 9.4e-05 58_[+4]_14 chr2:191049369-191049449 0.00013 68_[+4]_4 chr2:38871051-38871131 0.00019 16_[+4]_56 chr13:25968978-25969058 0.00019 18_[+4]_54 chr6:119863385-119863465 0.00019 57_[+4]_15 chr11:71639559-71639639 0.00019 48_[+4]_24 chr22:37948841-37948921 0.00024 12_[+4]_60 chr19:47931506-47931586 0.00024 48_[+4]_24 chrX:65218094-65218174 0.0003 50_[+4]_22 chr2:242824077-242824157 0.0003 32_[+4]_40 chr17:4843528-4843608 0.0003 70_[+4]_2 chr16:89359965-89360045 0.0003 19_[+4]_53 chr11:107885883-10788596 0.00035 2_[+4]_70 chr20:46012907-46012987 0.00035 69_[+4]_3 chr1:70005893-70005973 0.00035 32_[+4]_40 chr2:43154850-43154930 0.0004 71_[+4]_1 chr17:27717290-27717370 0.0004 61_[+4]_11 chr5:39194731-39194811 0.0004 39_[+4]_33 chr14:55221585-55221665 0.0004 56_[+4]_16 chr19:52051129-52051209 0.0004 39_[+4]_33 chr22:23624100-23624180 0.0004 15_[+4]_57 chr10:5024331-5024411 0.0004 23_[+4]_49 chr9:125209239-125209319 0.0004 32_[+4]_40 chr6:53224467-53224547 0.00046 2_[+4]_70 chr8:93107702-93107782 0.00046 24_[+4]_48 chr15:56612693-56612773 0.00046 4_[+4]_68 chr8:37939595-37939675 0.00049 40_[+4]_32 chr11:125423010-12542309 0.00055 10_[+4]_62 chr10:51565111-51565191 0.00056 61_[+4]_11 chr2:198794145-198794225 0.0006 33_[+4]_39 chr3:14162496-14162576 0.00062 45_[+4]_27 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif RRGTGSAG MEME-4 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF RRGTGSAG width=8 seqs=52 chr1:201528951-201529031 ( 13) GGGTGCAG 1 chr11:5186199-5186279 ( 46) GGGTGCAG 1 chr5:131651365-131651445 ( 27) GGGTGCAG 1 chr6:16263865-16263945 ( 59) GGGTGCAG 1 chr7:7082273-7082353 ( 58) GGGTGCAG 1 chr1:35602548-35602628 ( 59) GGGTGCAG 1 chr4:95309280-95309360 ( 59) GGGTGCAG 1 chr9:102907628-102907708 ( 37) GGGTGCAG 1 chr12:133047863-13304794 ( 63) AGGTGCAG 1 chr8:130594485-130594565 ( 17) AGGTGCAG 1 chr14:102144480-10214456 ( 50) AGGTGCAG 1 chr16:517816-517896 ( 6) AGGTGCAG 1 chr16:517616-517696 ( 52) AGGTGCAG 1 chr7:65580469-65580549 ( 3) GGGTGGAG 1 chr20:23113758-23113838 ( 31) GGGTGGAG 1 chr10:51565312-51565392 ( 3) GGGTGGAG 1 chr19:1123170-1123250 ( 40) GGGTGGAG 1 chr22:36764702-36764782 ( 11) AGGTGGAG 1 chr3:16977885-16977965 ( 26) AGGTGGAG 1 chr18:968420-968500 ( 62) GAGTGCAG 1 chr1:25606332-25606412 ( 72) GAGTGCAG 1 chr12:132166853-13216693 ( 59) AGGTGGAG 1 chr2:191049369-191049449 ( 69) GGGTGCTG 1 chr2:38871051-38871131 ( 17) GAGTGGAG 1 chr13:25968978-25969058 ( 19) GAGTGGAG 1 chr6:119863385-119863465 ( 58) AGGTGCTG 1 chr11:71639559-71639639 ( 49) AGGTGCTG 1 chr22:37948841-37948921 ( 13) AGGAGCAG 1 chr19:47931506-47931586 ( 49) AAGTGGAG 1 chrX:65218094-65218174 ( 51) AGGTGGTG 1 chr2:242824077-242824157 ( 33) AGGTGGTG 1 chr17:4843528-4843608 ( 71) AGGTGGTG 1 chr16:89359965-89360045 ( 20) GGGAGGAG 1 chr11:107885883-10788596 ( 3) AAGTGCTG 1 chr20:46012907-46012987 ( 70) GAGAGCAG 1 chr1:70005893-70005973 ( 33) AAGTGCTG 1 chr2:43154850-43154930 ( 72) GGGAGCTG 1 chr17:27717290-27717370 ( 62) GAGTGGTG 1 chr5:39194731-39194811 ( 40) AAGAGCAG 1 chr14:55221585-55221665 ( 57) GGGAGCTG 1 chr19:52051129-52051209 ( 40) AAGAGCAG 1 chr22:23624100-23624180 ( 16) GGGAGCTG 1 chr10:5024331-5024411 ( 24) GAGTGGTG 1 chr9:125209239-125209319 ( 33) AAGAGCAG 1 chr6:53224467-53224547 ( 3) GAGAGGAG 1 chr8:93107702-93107782 ( 25) GAGAGGAG 1 chr15:56612693-56612773 ( 5) GAGAGGAG 1 chr8:37939595-37939675 ( 41) GGGAGGTG 1 chr11:125423010-12542309 ( 11) AAGAGCTG 1 chr10:51565111-51565191 ( 62) GAGAGGTG 1 chr2:198794145-198794225 ( 34) GGCTGCAG 1 chr3:14162496-14162576 ( 46) AGCTGCAG 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif RRGTGSAG MEME-4 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 9.61772 E= 7.6e+000 81 -1234 112 -1234 53 -1234 130 -1234 -1234 -273 185 -1234 26 -1234 -1234 157 -1234 -1234 191 -1234 -1234 123 60 -1234 153 -1234 -1234 37 -1234 -1234 191 -1234 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif RRGTGSAG MEME-4 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 52 E= 7.6e+000 0.423077 0.000000 0.576923 0.000000 0.346154 0.000000 0.653846 0.000000 0.000000 0.038462 0.961538 0.000000 0.288462 0.000000 0.000000 0.711538 0.000000 0.000000 1.000000 0.000000 0.000000 0.596154 0.403846 0.000000 0.692308 0.000000 0.000000 0.307692 0.000000 0.000000 1.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif RRGTGSAG MEME-4 regular expression -------------------------------------------------------------------------------- [GA][GA]G[TA]G[CG][AT]G -------------------------------------------------------------------------------- Time 15.89 secs. ******************************************************************************** ******************************************************************************** MOTIF KTWTTTCC MEME-5 width = 8 sites = 11 llr = 110 E-value = 1.2e+004 ******************************************************************************** -------------------------------------------------------------------------------- Motif KTWTTTCC MEME-5 Description -------------------------------------------------------------------------------- Simplified A ::4::::: pos.-specific C ::::::aa probability G 4::::::: matrix T 6a6aaa:: bits 2.1 * ***** 1.9 * ***** 1.7 * ***** 1.4 * ***** Relative 1.2 * ***** Entropy 1.0 ******** (14.4 bits) 0.8 ******** 0.6 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel TTTTTTCC consensus G A sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif KTWTTTCC MEME-5 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr2:169990948-169991028 52 1.21e-05 ccatatttcc ttttttcc tgttcctcac chr2:172865174-172865254 17 1.21e-05 TGTCTGAAGT TTTTTTCC CCAACTTCGG chr14:21852248-21852328 23 1.21e-05 tttgttttgt ttttttCC AACCCTCTTT chr9:35004446-35004526 8 2.43e-05 cgatccc ttatttcc atgccccgac chr11:68391362-68391442 26 2.43e-05 ccctgatccc ttatttcc atgccccgac chr6:142337978-142338058 11 2.43e-05 ccccaatccc ttatttcc acaccccaac chr17:11876215-11876295 12 2.43e-05 ccccaatccc ttatttcc acaccccaac chr3:186589330-186589410 64 3.78e-05 TCTTACCCCT GTTTTTCC CCAAAATCA chr19:21785809-21785889 73 3.78e-05 cgtaaaacat gtttttcc chr8:130594485-130594565 45 3.78e-05 GAGGAAACTT GTTTTTCC GTTGGTTTCT chr19:45909735-45909815 63 3.78e-05 ATTTTCCCCA GTTTTTCC TGCAGATCGG -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif KTWTTTCC MEME-5 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr2:169990948-169991028 1.2e-05 51_[+5]_21 chr2:172865174-172865254 1.2e-05 16_[+5]_56 chr14:21852248-21852328 1.2e-05 22_[+5]_50 chr9:35004446-35004526 2.4e-05 7_[+5]_65 chr11:68391362-68391442 2.4e-05 25_[+5]_47 chr6:142337978-142338058 2.4e-05 10_[+5]_62 chr17:11876215-11876295 2.4e-05 11_[+5]_61 chr3:186589330-186589410 3.8e-05 63_[+5]_9 chr19:21785809-21785889 3.8e-05 72_[+5] chr8:130594485-130594565 3.8e-05 44_[+5]_28 chr19:45909735-45909815 3.8e-05 62_[+5]_10 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif KTWTTTCC MEME-5 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF KTWTTTCC width=8 seqs=11 chr2:169990948-169991028 ( 52) TTTTTTCC 1 chr2:172865174-172865254 ( 17) TTTTTTCC 1 chr14:21852248-21852328 ( 23) TTTTTTCC 1 chr9:35004446-35004526 ( 8) TTATTTCC 1 chr11:68391362-68391442 ( 26) TTATTTCC 1 chr6:142337978-142338058 ( 11) TTATTTCC 1 chr17:11876215-11876295 ( 12) TTATTTCC 1 chr3:186589330-186589410 ( 64) GTTTTTCC 1 chr19:21785809-21785889 ( 73) GTTTTTCC 1 chr8:130594485-130594565 ( 45) GTTTTTCC 1 chr19:45909735-45909815 ( 63) GTTTTTCC 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif KTWTTTCC MEME-5 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 12.2293 E= 1.2e+004 -1010 -1010 45 141 -1010 -1010 -1010 206 60 -1010 -1010 141 -1010 -1010 -1010 206 -1010 -1010 -1010 206 -1010 -1010 -1010 206 -1010 197 -1010 -1010 -1010 197 -1010 -1010 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif KTWTTTCC MEME-5 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 11 E= 1.2e+004 0.000000 0.000000 0.363636 0.636364 0.000000 0.000000 0.000000 1.000000 0.363636 0.000000 0.000000 0.636364 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif KTWTTTCC MEME-5 regular expression -------------------------------------------------------------------------------- [TG]T[TA]TTTCC -------------------------------------------------------------------------------- Time 19.36 secs. ******************************************************************************** ******************************************************************************** SUMMARY OF MOTIFS ******************************************************************************** -------------------------------------------------------------------------------- Combined block diagrams: non-overlapping sites with p-value < 0.0001 -------------------------------------------------------------------------------- SEQUENCE NAME COMBINED P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr7:6543433-6543513 5.47e-01 80 chr16:517616-517696 2.71e-01 51_[+4(3.73e-05)]_21 chr16:517816-517896 2.71e-01 5_[+4(3.73e-05)]_58_[+4(3.73e-05)]_\ 1 chr19:1123170-1123250 3.33e-01 39_[+4(5.77e-05)]_33 chr2:17699738-17699818 3.40e-01 80 chr12:132166853-13216693 3.79e-01 58_[+4(9.39e-05)]_14 chr13:114428190-11442827 9.96e-01 80 chr16:22202026-22202106 8.34e-01 80 chr6:169825686-169825766 9.83e-01 80 chr16:89359965-89360045 6.28e-01 80 chr9:130981143-130981223 8.55e-01 80 chr17:11876215-11876295 2.80e-03 11_[+5(2.43e-05)]_12_[+2(1.30e-05)]_\ 14_[+5(2.43e-05)]_19 chr19:4328486-4328566 9.98e-01 80 chr9:102907628-102907708 4.52e-03 2_[+1(2.97e-05)]_26_[+4(1.96e-05)]_\ 36 chr2:242823863-242823943 6.60e-01 80 chr14:21852248-21852328 3.24e-02 22_[+5(1.21e-05)]_50 chr3:152949165-152949245 1.37e-01 26_[+1(2.97e-05)]_34_[+1(2.97e-05)]_\ 4 chr16:22202235-22202315 9.96e-01 80 chr17:4843528-4843608 3.93e-03 25_[+3(1.62e-05)]_47 chr4:95309280-95309360 4.21e-03 16_[+4(1.96e-05)]_34_[+4(1.96e-05)]_\ 14 chr19:18747420-18747500 9.92e-01 80 chr17:549357-549437 1.19e-04 26_[+1(4.41e-05)]_3_[+2(2.53e-05)]_\ 35 chr14:88491085-88491165 1.14e-01 70_[+1(2.97e-05)]_2 chr16:1393181-1393261 7.69e-01 80 chr8:144302022-144302102 9.98e-01 80 chr1:169337252-169337332 6.19e-01 80 chr2:242824077-242824157 2.88e-01 80 chr1:35602548-35602628 4.68e-03 23_[+1(2.97e-05)]_27_[+4(1.96e-05)]_\ 14 chr3:49131519-49131599 2.13e-02 1_[+3(1.62e-05)]_71 chr4:129566589-129566669 1.07e-01 40_[+1(2.97e-05)]_32 chr6:142337978-142338058 2.98e-03 10_[+5(2.43e-05)]_12_[+2(1.30e-05)]_\ 14_[+5(2.43e-05)]_12_[+2(1.30e-05)] chr6:82915905-82915985 6.06e-01 80 chr14:35122457-35122537 3.22e-02 50_[+1(4.41e-05)]_22 chr10:51565111-51565191 1.95e-02 35_[+3(1.62e-05)]_37 chr14:102144480-10214456 1.02e-02 49_[+4(3.73e-05)]_23 chr9:140044931-140045011 2.60e-01 26_[+1(9.98e-05)]_46 chr1:25611742-25611822 1.95e-01 80 chr17:62919208-62919288 4.84e-01 80 chr11:71639559-71639639 1.46e-01 80 chr9:98637851-98637931 6.42e-03 29_[+3(1.62e-05)]_27_[+3(3.40e-05)]_\ 8 chr3:171164805-171164885 2.24e-02 [+2(1.30e-05)]_72 chr7:7082273-7082353 4.36e-03 57_[+4(1.96e-05)]_15 chr16:89259045-89259125 9.46e-01 80 chr6:44355224-44355304 5.61e-04 20_[+3(1.62e-05)]_52 chr19:2151746-2151826 8.12e-01 80 chr11:68391362-68391442 2.76e-03 3_[+2(1.30e-05)]_14_[+5(2.43e-05)]_\ 12_[+2(1.30e-05)]_27 chr12:101673920-10167400 7.20e-01 80 chr1:244436430-244436510 5.37e-01 80 chrX:40032082-40032162 2.28e-01 80 chr10:4892023-4892103 5.18e-01 80 chr17:53046026-53046106 3.77e-02 29_[+3(1.62e-05)]_11_[+3(1.62e-05)]_\ 24 chr2:178483550-178483630 3.33e-01 80 chr19:1490729-1490809 1.66e-01 80 chr20:9129838-9129918 1.35e-01 80 chr10:51565312-51565392 1.84e-01 2_[+4(5.77e-05)]_70 chr4:144940578-144940658 5.24e-01 80 chr6:35995408-35995488 2.45e-02 17_[+3(1.62e-05)]_55 chr20:23113758-23113838 1.72e-03 30_[+4(5.77e-05)]_34_[+1(1.45e-05)] chr17:53894317-53894397 4.94e-01 80 chr15:56612693-56612773 2.80e-02 80 chr2:219433404-219433484 5.80e-01 80 chr6:30585391-30585471 9.77e-01 80 chr5:131450380-131450460 4.79e-01 80 chr1:25606332-25606412 1.65e-02 71_[+4(9.39e-05)]_1 chr1:211395910-211395990 5.33e-02 52_[+2(1.30e-05)]_20 chr9:125209239-125209319 1.01e-04 5_[+2(2.53e-05)]_38_[+1(1.45e-05)]_\ 21 chr15:78730331-78730411 2.11e-01 80 chr8:93107702-93107782 2.69e-01 80 chr19:49999420-49999500 7.20e-01 80 chr6:42012091-42012171 9.72e-01 80 chrX:10087619-10087699 2.15e-01 80 chr9:35004446-35004526 2.86e-03 7_[+5(2.43e-05)]_12_[+2(1.30e-05)]_\ 14_[+5(2.43e-05)]_12_[+2(1.30e-05)]_3 chr9:73100399-73100479 1.04e-01 27_[+2(3.89e-05)]_45 chr7:105752869-105752949 7.40e-01 80 chr22:40316291-40316371 7.98e-02 80 chr8:98790762-98790842 5.09e-01 80 chr6:16263865-16263945 4.68e-03 16_[+4(1.96e-05)]_34_[+4(1.96e-05)]_\ 14 chr8:126954478-126954558 8.94e-02 80 chr8:38068325-38068405 9.29e-02 80 chr1:160919195-160919275 2.17e-01 80 chr9:136159297-136159377 6.96e-02 80 chr16:70470017-70470097 2.18e-01 80 chr12:49351266-49351346 6.33e-02 80 chr19:45909735-45909815 9.98e-02 62_[+5(3.78e-05)]_10 chr2:192701665-192701745 5.01e-01 80 chr19:42612812-42612892 5.92e-01 80 chr2:25479546-25479626 6.20e-02 7_[+2(2.53e-05)]_12_[+2(2.53e-05)]_\ 12_[+2(2.53e-05)]_25 chr4:54232173-54232253 9.70e-01 80 chr7:129409107-129409187 4.82e-01 80 chr19:47760522-47760602 7.23e-01 80 chr12:29534127-29534207 1.03e-03 55_[+3(1.62e-05)]_17 chr9:140513122-140513202 5.26e-01 80 chr2:219712513-219712593 1.51e-01 80 chr4:25052514-25052594 2.45e-02 25_[+1(1.45e-05)]_47 chr19:18747625-18747705 6.67e-01 80 chr11:67764443-67764523 5.75e-01 80 chr7:104607695-104607775 2.46e-02 17_[+1(8.66e-05)]_55 chr1:78148349-78148429 5.46e-02 17_[+3(1.62e-05)]_16_[+3(1.62e-05)]_\ 31 chr9:35728596-35728676 1.25e-01 1_[+2(8.99e-05)]_71 chr9:4863144-4863224 8.09e-01 80 chr6:28514944-28515024 8.58e-02 12_[+1(7.29e-05)]_41_[+1(7.29e-05)]_\ 11 chr3:47388933-47389013 3.31e-01 80 chr4:17812523-17812603 2.26e-02 11_[+3(3.40e-05)]_10_[+3(3.40e-05)]_\ 43 chr1:70005893-70005973 1.32e-02 80 chr5:131651365-131651445 6.38e-03 26_[+4(1.96e-05)]_46 chr12:123237304-12323738 9.35e-03 15_[+3(1.62e-05)]_23_[+3(1.62e-05)]_\ 13_[+3(3.40e-05)]_5 chr13:44972132-44972212 7.40e-03 42_[+2(8.99e-05)]_30 chr3:126630368-126630448 2.05e-01 80 chr10:5024331-5024411 3.43e-02 39_[+1(7.29e-05)]_33 chrX:65218094-65218174 1.57e-02 59_[+1(1.45e-05)]_13 chr17:37617609-37617689 4.00e-03 18_[+3(6.71e-05)]_54 chr9:4862945-4863025 2.75e-02 60_[+1(9.98e-05)]_12 chr14:20645713-20645793 3.85e-02 35_[+2(8.99e-05)]_37 chr13:95923636-95923716 7.35e-01 80 chr4:69730308-69730388 3.69e-01 80 chr19:10812040-10812120 8.85e-01 80 chr12:4262871-4262951 2.49e-01 80 chr1:15110688-15110768 9.77e-02 80 chr3:32115890-32115970 2.20e-02 80 chr2:86416691-86416771 8.11e-01 80 chr6:27741819-27741899 9.71e-02 80 chr12:114404045-11440412 4.55e-01 80 chr1:25739903-25739983 7.08e-02 66_[+1(7.29e-05)]_6 chr5:131987933-131988013 1.46e-01 39_[+1(7.29e-05)]_33 chr7:43026528-43026608 1.61e-02 20_[+1(7.29e-05)]_52 chrX:151345707-151345787 3.46e-02 80 chr11:12171498-12171578 4.89e-02 6_[+1(7.29e-05)]_66 chr3:14162496-14162576 2.37e-01 80 chr17:60311538-60311618 9.35e-03 23_[+1(2.97e-05)]_49 chr17:4167238-4167318 1.39e-01 21_[+3(8.43e-05)]_51 chr20:17906256-17906336 1.67e-03 30_[+1(2.97e-05)]_42 chr16:20685563-20685643 3.97e-02 5_[+2(1.30e-05)]_67 chrX:119468573-119468653 5.21e-03 22_[+1(4.41e-05)]_50 chr5:176421945-176422025 4.54e-01 80 chr4:1884780-1884860 2.79e-01 80 chr13:95923435-95923515 1.87e-01 80 chr6:125404414-125404494 7.56e-01 80 chr8:130594485-130594565 3.99e-04 16_[+4(3.73e-05)]_20_[+5(3.78e-05)]_\ 28 chr7:65580469-65580549 1.82e-01 2_[+4(5.77e-05)]_70 chr11:125423010-12542309 2.19e-02 40_[+1(1.45e-05)]_32 chr2:172865174-172865254 7.70e-02 16_[+5(1.21e-05)]_56 chr20:33780336-33780416 2.67e-01 80 chrX:49100807-49100887 8.42e-01 80 chr18:67693006-67693086 5.61e-02 80 chr9:101694447-101694527 1.09e-02 32_[+2(1.30e-05)]_40 chr15:22833365-22833445 6.88e-02 56_[+3(1.62e-05)]_16 chr5:131332575-131332655 3.39e-01 80 chr14:36733954-36734034 8.66e-02 80 chr18:968420-968500 2.41e-02 61_[+4(9.39e-05)]_11 chr22:23624100-23624180 5.31e-01 80 chr19:47931506-47931586 3.22e-01 80 chr5:148018813-148018893 3.22e-01 80 chr20:46012907-46012987 1.36e-01 80 chr16:23833435-23833515 5.49e-01 80 chr13:109421983-10942206 1.69e-01 80 chr6:119863385-119863465 7.76e-03 80 chr8:130705177-130705257 5.07e-01 80 chr2:169990948-169991028 4.35e-02 51_[+5(1.21e-05)]_21 chr3:195805977-195806057 1.40e-01 80 chr5:180209025-180209105 1.20e-01 80 chr5:1067938-1068018 5.02e-01 80 chr12:58165792-58165872 9.43e-01 80 chr18:8913728-8913808 6.44e-01 80 chr9:138842307-138842387 7.16e-02 80 chr19:516748-516828 9.42e-02 70_[+1(8.66e-05)]_2 chr14:31291375-31291455 7.88e-03 21_[+1(2.97e-05)]_51 chr2:198794145-198794225 7.22e-03 51_[+1(1.45e-05)]_21 chr4:80131432-80131512 1.65e-01 80 chr2:230786990-230787070 6.03e-01 80 chr19:52051129-52051209 9.91e-05 12_[+2(2.53e-05)]_38_[+1(1.45e-05)]_\ 14 chr22:22818576-22818656 9.83e-01 80 chr5:131649930-131650010 3.44e-01 80 chr6:37151148-37151228 4.71e-01 80 chr4:81100942-81101022 6.33e-03 80 chr1:156571205-156571285 3.89e-01 80 chr22:32022697-32022777 4.77e-01 80 chr19:35411469-35411549 9.48e-01 80 chrX:102356735-102356815 7.16e-02 21_[+1(7.29e-05)]_51 chr8:37939595-37939675 9.57e-02 80 chr14:102414492-10241457 2.43e-03 10_[+3(1.62e-05)]_62 chr9:38171075-38171155 8.74e-01 80 chr4:68418035-68418115 1.96e-01 80 chr5:89940148-89940228 9.03e-01 80 chr3:46530358-46530438 8.62e-01 80 chr3:49398931-49399011 6.16e-02 16_[+2(2.53e-05)]_56 chr14:69186595-69186675 3.39e-02 80 chr4:56596106-56596186 6.96e-01 80 chr3:98302749-98302829 4.04e-01 80 chr1:61514693-61514773 7.67e-03 3_[+1(2.97e-05)]_69 chr22:37948841-37948921 2.44e-02 80 chr12:116823781-11682386 1.13e-01 80 chr11:5186199-5186279 4.21e-03 24_[+4(1.96e-05)]_13_[+4(1.96e-05)]_\ 13_[+4(1.96e-05)]_6 chr2:191049369-191049449 4.57e-02 80 chr14:55221585-55221665 1.71e-01 80 chr1:201528951-201529031 6.54e-02 12_[+4(1.96e-05)]_60 chr7:92515504-92515584 3.30e-01 80 chr19:21785809-21785889 3.83e-03 47_[+1(9.98e-05)]_17_[+5(3.78e-05)] chr19:7894851-7894931 7.22e-02 80 chr12:133047863-13304794 1.70e-01 62_[+4(3.73e-05)]_10 chr9:138360882-138360962 2.55e-01 80 chr3:16977885-16977965 1.80e-01 25_[+4(9.39e-05)]_47 chr13:38533669-38533749 3.30e-01 80 chr7:75943706-75943786 4.26e-01 80 chr4:144826750-144826830 1.91e-02 [+2(8.99e-05)]_72 chr8:20809653-20809733 5.90e-03 57_[+2(8.99e-05)]_15 chr3:125152066-125152146 1.61e-01 80 chr18:77361320-77361400 3.43e-01 80 chr12:92798821-92798901 1.07e-01 52_[+2(2.53e-05)]_20 chr5:39194731-39194811 1.59e-03 29_[+2(2.53e-05)]_43 chr20:34330251-34330331 4.64e-02 62_[+3(6.71e-05)]_10 chr16:11196068-11196148 1.50e-01 29_[+1(4.41e-05)]_43 chr1:19923371-19923451 8.20e-03 40_[+3(1.62e-05)]_32 chr4:15683210-15683290 3.93e-01 80 chr13:111617760-11161784 5.99e-01 80 chr16:25783263-25783343 4.35e-03 68_[+1(1.45e-05)]_4 chr17:27717290-27717370 1.04e-02 19_[+3(1.62e-05)]_53 chr17:40714081-40714161 1.38e-02 3_[+3(1.62e-05)]_69 chr22:36764702-36764782 1.21e-03 10_[+4(9.39e-05)]_4_[+2(5.25e-05)]_\ 50 chr8:37949384-37949464 3.39e-02 54_[+1(1.45e-05)]_18 chr2:677400-677480 1.46e-02 66_[+3(3.40e-05)]_6 chr7:77502870-77502950 1.51e-01 80 chr3:5468212-5468292 1.77e-01 80 chr3:195577851-195577931 6.22e-01 80 chr15:51944717-51944797 1.08e-01 80 chr19:14618685-14618765 1.43e-01 80 chr16:15615895-15615975 3.85e-02 80 chr4:144775958-144776038 1.90e-01 80 chr2:43154850-43154930 2.47e-01 80 chrX:11479838-11479918 1.28e-01 80 chr6:52168905-52168985 2.05e-01 80 chr3:4266828-4266908 2.44e-01 80 chr17:65852270-65852350 5.36e-02 63_[+2(2.53e-05)]_9 chr13:25968978-25969058 1.43e-03 54_[+2(2.53e-05)]_18 chr15:66097594-66097674 6.70e-01 80 chr19:4247672-4247752 3.60e-02 80 chr1:27226906-27226986 7.72e-02 59_[+3(1.62e-05)]_13 chr6:53224467-53224547 4.24e-01 80 chr1:5946022-5946102 1.54e-03 19_[+2(1.30e-05)]_53 chr3:141567992-141568072 1.79e-02 64_[+1(4.41e-05)]_8 chr3:186589330-186589410 4.68e-03 63_[+5(3.78e-05)]_9 chr2:38871051-38871131 2.64e-01 80 chr5:98290521-98290601 7.12e-01 80 chr11:107885883-10788596 1.46e-02 80 chr10:29295066-29295146 3.30e-01 80 chr8:37749448-37749528 6.58e-01 80 chr1:65696954-65697034 3.37e-02 80 chr2:145199439-145199519 1.34e-01 80 chr13:27557249-27557329 4.71e-01 80 chr17:57367827-57367907 2.20e-01 80 chr2:32853230-32853310 4.27e-01 80 -------------------------------------------------------------------------------- ******************************************************************************** ******************************************************************************** Stopped because requested number of motifs (5) found. ******************************************************************************** CPU: c22n04.farnam.hpc.yale.internal ********************************************************************************