******************************************************************************** MEME - Motif discovery tool ******************************************************************************** MEME version 5.3.3 (Release date: Sun Feb 7 15:39:52 2021 -0800) For further information on how to interpret these results please access https://meme-suite.org/meme. To get a copy of the MEME Suite software please access https://meme-suite.org. ******************************************************************************** ******************************************************************************** REFERENCE ******************************************************************************** If you use this program in your research, please cite: Timothy L. Bailey and Charles Elkan, "Fitting a mixture model by expectation maximization to discover motifs in biopolymers", Proceedings of the Second International Conference on Intelligent Systems for Molecular Biology, pp. 28-36, AAAI Press, Menlo Park, California, 1994. ******************************************************************************** ******************************************************************************** TRAINING SET ******************************************************************************** PRIMARY SEQUENCES= ../result/final_prediction/K562/fasta/RankLinear0.6_40/NBN.fasta CONTROL SEQUENCES= --none-- ALPHABET= ACGT Sequence name Weight Length Sequence name Weight Length ------------- ------ ------ ------------- ------ ------ chr1:10049-10129 1.0000 80 chr2:243153822-243153902 1.0000 80 chr2:11607-11687 1.0000 80 chr18:11674-11754 1.0000 80 chr17:79093597-79093677 1.0000 80 chr11:134945692-13494577 1.0000 80 chr2:19548149-19548229 1.0000 80 chr6:139456066-139456146 1.0000 80 chr19:17728312-17728392 1.0000 80 chr14:68086437-68086517 1.0000 80 chr19:50979516-50979596 1.0000 80 chr4:119512822-119512902 1.0000 80 chr1:249240178-249240258 1.0000 80 chr5:95297753-95297833 1.0000 80 chr2:74781530-74781610 1.0000 80 chr11:77185401-77185481 1.0000 80 chr15:102520935-10252101 1.0000 80 chr19:50862181-50862261 1.0000 80 chr8:21967225-21967305 1.0000 80 chr1:224180298-224180378 1.0000 80 chr7:159128355-159128435 1.0000 80 chr7:45808606-45808686 1.0000 80 chr2:170696738-170696818 1.0000 80 chr21:43430342-43430422 1.0000 80 chr1:4052256-4052336 1.0000 80 chr6:15248926-15249006 1.0000 80 chr7:137686977-137687057 1.0000 80 chr13:49821989-49822069 1.0000 80 chr2:28114101-28114181 1.0000 80 chr4:170541640-170541720 1.0000 80 chr17:38136743-38136823 1.0000 80 chr2:2577813-2577893 1.0000 80 chr19:36103552-36103632 1.0000 80 chr12:64616303-64616383 1.0000 80 chr19:17462815-17462895 1.0000 80 chr6:143381661-143381741 1.0000 80 chr9:33001613-33001693 1.0000 80 chr18:10097-10177 1.0000 80 chr7:65235816-65235896 1.0000 80 chr11:95523546-95523626 1.0000 80 chr6:53213772-53213852 1.0000 80 chr7:6413556-6413636 1.0000 80 chr8:146294970-146295050 1.0000 80 chr11:3818985-3819065 1.0000 80 chr19:56015258-56015338 1.0000 80 chr10:74397398-74397478 1.0000 80 chr18:76829139-76829219 1.0000 80 chr5:137673177-137673257 1.0000 80 chr7:75795866-75795946 1.0000 80 chr18:33647545-33647625 1.0000 80 chr6:44355167-44355247 1.0000 80 chr10:70848851-70848931 1.0000 80 chr17:1196881-1196961 1.0000 80 chr15:34807470-34807550 1.0000 80 chr16:89766723-89766803 1.0000 80 chr5:11540-11620 1.0000 80 chr2:8144533-8144613 1.0000 80 chr7:149469098-149469178 1.0000 80 chr17:76554590-76554670 1.0000 80 chr18:2655138-2655218 1.0000 80 chr7:5492772-5492852 1.0000 80 chr19:47616923-47617003 1.0000 80 chr15:40401490-40401570 1.0000 80 chr9:100395594-100395674 1.0000 80 chr16:3285179-3285259 1.0000 80 chrX:135992426-135992506 1.0000 80 chr14:105219421-10521950 1.0000 80 chr4:120375787-120375867 1.0000 80 chr14:23388096-23388176 1.0000 80 chr7:44646064-44646144 1.0000 80 chr6:151362156-151362236 1.0000 80 chr7:140396442-140396522 1.0000 80 chr19:49164457-49164537 1.0000 80 chr12:31882013-31882093 1.0000 80 chr8:125486895-125486975 1.0000 80 chr14:50053228-50053308 1.0000 80 chr19:46009769-46009849 1.0000 80 chr1:243265037-243265117 1.0000 80 chr22:38576158-38576238 1.0000 80 chr14:55737961-55738041 1.0000 80 chr14:55738809-55738889 1.0000 80 chr19:7571595-7571675 1.0000 80 chr7:65958507-65958587 1.0000 80 chr7:39772934-39773014 1.0000 80 chr20:30192128-30192208 1.0000 80 chr19:51111407-51111487 1.0000 80 chr1:6320120-6320200 1.0000 80 chr19:59092676-59092756 1.0000 80 chr12:10766173-10766253 1.0000 80 chr17:7835466-7835546 1.0000 80 chr7:30174232-30174312 1.0000 80 chr6:148661-148741 1.0000 80 chr7:23571643-23571723 1.0000 80 chr7:149388146-149388226 1.0000 80 chr16:85604599-85604679 1.0000 80 chr18:23806271-23806351 1.0000 80 chr1:17004730-17004810 1.0000 80 chr5:65020530-65020610 1.0000 80 chr12:133022743-13302282 1.0000 80 chr19:59055494-59055574 1.0000 80 chr2:157192251-157192331 1.0000 80 chr1:2111911-2111991 1.0000 80 chr9:132539523-132539603 1.0000 80 chr16:75657141-75657221 1.0000 80 chr14:32030559-32030639 1.0000 80 chr7:55433934-55434014 1.0000 80 chr1:67944999-67945079 1.0000 80 chr17:40829281-40829361 1.0000 80 chr7:140624852-140624932 1.0000 80 chr3:38206506-38206586 1.0000 80 chr5:159436009-159436089 1.0000 80 chr12:131249248-13124932 1.0000 80 chr3:140660528-140660608 1.0000 80 chr11:190104-190184 1.0000 80 chr19:36119873-36119953 1.0000 80 chr8:144536788-144536868 1.0000 80 chr6:28756797-28756877 1.0000 80 chr7:99765621-99765701 1.0000 80 chr1:228296935-228297015 1.0000 80 chr12:123380768-12338084 1.0000 80 chr15:40401288-40401368 1.0000 80 chr7:44646264-44646344 1.0000 80 chr5:13292-13372 1.0000 80 chr11:4115967-4116047 1.0000 80 chr12:120729911-12072999 1.0000 80 chr22:21942495-21942575 1.0000 80 chr1:16872470-16872550 1.0000 80 chr1:156698651-156698731 1.0000 80 chr7:158990402-158990482 1.0000 80 chr11:85869980-85870060 1.0000 80 chr1:32110409-32110489 1.0000 80 chr14:31699034-31699114 1.0000 80 chr9:125027101-125027181 1.0000 80 chr7:129592772-129592852 1.0000 80 chr1:9489019-9489099 1.0000 80 chr16:57334190-57334270 1.0000 80 chr10:43876161-43876241 1.0000 80 chr17:56744256-56744336 1.0000 80 chr6:31939720-31939800 1.0000 80 chr17:45784184-45784264 1.0000 80 chr10:81963156-81963236 1.0000 80 chr12:58138352-58138432 1.0000 80 chr2:127066156-127066236 1.0000 80 chr19:8454834-8454914 1.0000 80 chr6:27125737-27125817 1.0000 80 chr1:714044-714124 1.0000 80 chr5:78810426-78810506 1.0000 80 chr9:111696365-111696445 1.0000 80 chr16:67924458-67924538 1.0000 80 chr12:56521642-56521722 1.0000 80 chr19:2962161-2962241 1.0000 80 chr6:37400923-37401003 1.0000 80 chr7:1546712-1546792 1.0000 80 chr1:110527275-110527355 1.0000 80 chr3:128598287-128598367 1.0000 80 chr8:145682209-145682289 1.0000 80 chr19:51506089-51506169 1.0000 80 chr10:75639463-75639543 1.0000 80 chr3:9464514-9464594 1.0000 80 chr1:147737229-147737309 1.0000 80 chr19:9546217-9546297 1.0000 80 chr6:3002421-3002501 1.0000 80 chr1:4067797-4067877 1.0000 80 chr6:3054188-3054268 1.0000 80 chr8:117768082-117768162 1.0000 80 chr19:51014783-51014863 1.0000 80 chr7:66309958-66310038 1.0000 80 chr16:84627760-84627840 1.0000 80 chr7:124569881-124569961 1.0000 80 chr15:42840942-42841022 1.0000 80 chr19:49004992-49005072 1.0000 80 chr17:38689738-38689818 1.0000 80 chr7:6488065-6488145 1.0000 80 chr1:1790231-1790311 1.0000 80 chr1:40840265-40840345 1.0000 80 chr5:159624897-159624977 1.0000 80 chr6:30028915-30028995 1.0000 80 chr19:55517486-55517566 1.0000 80 chr3:58291936-58292016 1.0000 80 chr7:100464925-100465005 1.0000 80 chr18:77866838-77866918 1.0000 80 chr1:203242454-203242534 1.0000 80 chr1:204675712-204675792 1.0000 80 chr1:27755019-27755099 1.0000 80 chr4:104119584-104119664 1.0000 80 chr20:44420492-44420572 1.0000 80 chr6:2846434-2846514 1.0000 80 chr2:191184683-191184763 1.0000 80 chr11:809824-809904 1.0000 80 chr19:46135924-46136004 1.0000 80 chr7:158990188-158990268 1.0000 80 chr12:132628914-13262899 1.0000 80 chr17:33914242-33914322 1.0000 80 chr1:936243-936323 1.0000 80 chr17:49010940-49011020 1.0000 80 chr16:86588813-86588893 1.0000 80 chr12:132344963-13234504 1.0000 80 chr11:3465439-3465519 1.0000 80 chr17:26662482-26662562 1.0000 80 chr12:110498140-11049822 1.0000 80 chr1:161500990-161501070 1.0000 80 chr6:31705872-31705952 1.0000 80 chr1:161067462-161067542 1.0000 80 chr7:100271186-100271266 1.0000 80 chr7:23230811-23230891 1.0000 80 chr7:143599122-143599202 1.0000 80 chr5:64372397-64372477 1.0000 80 chr6:7119748-7119828 1.0000 80 chr11:59315145-59315225 1.0000 80 chr7:23221562-23221642 1.0000 80 chr1:168147948-168148028 1.0000 80 chr16:68057124-68057204 1.0000 80 chr4:80131394-80131474 1.0000 80 chr4:113558039-113558119 1.0000 80 chr1:70820637-70820717 1.0000 80 chr7:86781388-86781468 1.0000 80 chr3:99536615-99536695 1.0000 80 chr8:54857713-54857793 1.0000 80 chr7:103560023-103560103 1.0000 80 chr6:138227402-138227482 1.0000 80 chr19:56825967-56826047 1.0000 80 chr6:15622026-15622106 1.0000 80 chr1:202522920-202523000 1.0000 80 chr11:111749988-11175006 1.0000 80 chr1:39456869-39456949 1.0000 80 chr19:11646978-11647058 1.0000 80 chr4:146019275-146019355 1.0000 80 chr1:249200547-249200627 1.0000 80 chr7:100076870-100076950 1.0000 80 chr2:105953796-105953876 1.0000 80 chr16:30887892-30887972 1.0000 80 chr11:75946659-75946739 1.0000 80 chr7:65564995-65565075 1.0000 80 chr1:247634573-247634653 1.0000 80 chr2:43823223-43823303 1.0000 80 chr6:27640101-27640181 1.0000 80 chr19:40923028-40923108 1.0000 80 chr15:91537885-91537965 1.0000 80 chr11:118481993-11848207 1.0000 80 chr2:68290122-68290202 1.0000 80 chr1:1655800-1655880 1.0000 80 chr17:44178629-44178709 1.0000 80 chr4:57253606-57253686 1.0000 80 chr6:43670450-43670530 1.0000 80 chr22:19803147-19803227 1.0000 80 chr16:28874671-28874751 1.0000 80 chr10:81205870-81205950 1.0000 80 chr6:34664808-34664888 1.0000 80 chr1:31297143-31297223 1.0000 80 chr15:66130024-66130104 1.0000 80 ******************************************************************************** ******************************************************************************** COMMAND LINE SUMMARY ******************************************************************************** This information can also be useful in the event you wish to report a problem with the MEME software. command: meme -oc ../result/final_prediction/K562/inference_raw/MEME/RankLinear0.6_40_NBN/ -dna -nmotifs 5 -w 8 -maxsize 250000 -nostatus ../result/final_prediction/K562/fasta/RankLinear0.6_40/NBN.fasta model: mod= zoops nmotifs= 5 evt= inf objective function: em= E-value of product of p-values starts= E-value of product of p-values strands: + width: minw= 8 maxw= 8 nsites: minsites= 2 maxsites= 250 wnsites= 0.8 theta: spmap= uni spfuzz= 0.5 em: prior= dirichlet b= 0.01 maxiter= 50 distance= 1e-05 trim: wg= 11 ws= 1 endgaps= yes data: n= 20000 N= 250 sample: seed= 0 hsfrac= 0 searchsize= 20000 norand= no csites= 1000 Letter frequencies in dataset: A 0.207 C 0.291 G 0.289 T 0.213 Background letter frequencies (from file dataset with add-one prior applied): A 0.207 C 0.291 G 0.289 T 0.213 Background model order: 0 ******************************************************************************** ******************************************************************************** MOTIF TGACGTCA MEME-1 width = 8 sites = 134 llr = 1399 E-value = 1.1e-263 ******************************************************************************** -------------------------------------------------------------------------------- Motif TGACGTCA MEME-1 Description -------------------------------------------------------------------------------- Simplified A ::a::::a pos.-specific C :::9::a: probability G :a::a::: matrix T a::1:a:: bits 2.3 * * 2.0 * * * * 1.8 *** *** 1.6 *** **** Relative 1.4 ******** Entropy 1.1 ******** (15.1 bits) 0.9 ******** 0.7 ******** 0.5 ******** 0.2 ******** 0.0 -------- Multilevel TGACGTCA consensus sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGACGTCA MEME-1 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr4:57253606-57253686 72 1.37e-05 CGTCGCTACG TGACGTCA G chr15:91537885-91537965 50 1.37e-05 CGGCGGGGGA TGACGTCA CTGTCTGTGA chr2:43823223-43823303 55 1.37e-05 GAGGAGGTCG TGACGTCA CCGGGGTGGC chr19:11646978-11647058 16 1.37e-05 AGTCATCGCG TGACGTCA CCGCCGCCTG chr1:39456869-39456949 41 1.37e-05 TGTGCGCCCG TGACGTCA CAGAAGGCGG chr19:56825967-56826047 42 1.37e-05 CCTCCGCCAG TGACGTCA CCGCAAGGGC chr3:99536615-99536695 62 1.37e-05 GGCAGAGGTG TGACGTCA TCGCCGCGGG chr4:113558039-113558119 17 1.37e-05 CGAAACAACG TGACGTCA TTAACGCGGG chr16:68057124-68057204 14 1.37e-05 CGCACATCAG TGACGTCA CGGACGCGCC chr1:168147948-168148028 21 1.37e-05 TCCTTCGAGA TGACGTCA CCCAACGAGT chr7:23221562-23221642 32 1.37e-05 CGCGAGAAGA TGACGTCA CAGTAGCCCG chr17:26662482-26662562 16 1.37e-05 TGTTTACCTA TGACGTCA CTACCTTCCT chr16:86588813-86588893 28 1.37e-05 TGGCGCGTAG TGACGTCA CCCGCTCCGC chr1:936243-936323 55 1.37e-05 CCTGCTGGGA TGACGTCA TGTGGCCCGT chr17:33914242-33914322 36 1.37e-05 CGACGTTCTC TGACGTCA GAGTTTCCTG chr12:132628914-13262899 63 1.37e-05 CGCGCAGTGG TGACGTCA CGGGAGCGCC chr19:46135924-46136004 63 1.37e-05 GCCCTCATTG TGACGTCA CAGAGGCGGG chr11:809824-809904 50 1.37e-05 GAGCGCCTCG TGACGTCA CTCTGAGGCG chr4:104119584-104119664 23 1.37e-05 CGTGGCCTCG TGACGTCA TGGGCCATTC chr18:77866838-77866918 51 1.37e-05 ACCCCTTTAG TGACGTCA TTGCCCACTC chr7:100464925-100465005 24 1.37e-05 AGGAATGTGG TGACGTCA TCGGAGGCGT chr3:58291936-58292016 29 1.37e-05 CGCCGCGTGG TGACGTCA TATCCGCCTG chr19:55517486-55517566 61 1.37e-05 AGACAGGAAG TGACGTCA AACCAGGATT chr6:30028915-30028995 52 1.37e-05 CAATTAATTA TGACGTCA CAGCCAATCG chr1:1790231-1790311 23 1.37e-05 cccttcccga tgacgtca catcctaata chr15:42840942-42841022 49 1.37e-05 GAACGCCCTG TGACGTCA TCGAGCCGCG chr7:124569881-124569961 14 1.37e-05 GGCGCGCAGG TGACGTCA CACGCACGCT chr7:66309958-66310038 17 1.37e-05 GCGCCTTCGC TGACGTCA CAGGCGCGGG chr19:51014783-51014863 34 1.37e-05 AGACGCAGCG TGACGTCA CACAAGGGAA chr8:117768082-117768162 19 1.37e-05 AAGTCTCGCG TGACGTCA CTCGCAGGCC chr19:9546217-9546297 42 1.37e-05 CAGCGCTCCG TGACGTCA CTTCCGCCTC chr19:51506089-51506169 35 1.37e-05 TGGCTGTCGG TGACGTCA TAGAGACGGG chr3:128598287-128598367 18 1.37e-05 CGTAGGCGTG TGACGTCA TCAGGCGGCG chr1:110527275-110527355 22 1.37e-05 CCCAGCGTGG TGACGTCA CGACAGAGTG chr6:37400923-37401003 50 1.37e-05 GCGCTGTCCG TGACGTCA TCAGGCTGCG chr19:2962161-2962241 38 1.37e-05 tttaaatgta tgacgtca tcttatgtaa chr12:56521642-56521722 47 1.37e-05 CAGCTCTGCA TGACGTCA TACCACAGGC chr9:111696365-111696445 50 1.37e-05 GGCGCGGGAG TGACGTCA CCAGGCGGAG chr1:714044-714124 49 1.37e-05 CGCACCCTTG TGACGTCA CAGGGGACTA chr19:8454834-8454914 24 1.37e-05 CGCTGACCTA TGACGTCA TCGGGACGTT chr6:31939720-31939800 21 1.37e-05 CGCAGAGCTA TGACGTCA TGGCAGGCAC chr17:56744256-56744336 24 1.37e-05 CCTCCCGGCG TGACGTCA TGCATAGGCC chr1:9489019-9489099 24 1.37e-05 CGCGGGTGTG TGACGTCA TCTGAGAGCG chr7:129592772-129592852 51 1.37e-05 GTCACCTCTG TGACGTCA TCGGAGGGGC chr9:125027101-125027181 42 1.37e-05 CCTGGCTTCG TGACGTCA CGACGTCCGC chr1:32110409-32110489 65 1.37e-05 ATGGTGATTC TGACGTCA CACTCAGG chr12:120729911-12072999 30 1.37e-05 CAAATCAACG TGACGTCA CAGAGATGAC chr19:36119873-36119953 41 1.37e-05 CCCGAATGTA TGACGTCA TGCGCCAGCG chr3:140660528-140660608 33 1.37e-05 GCAGAGTGCG TGACGTCA CGACGCTCAC chr5:159436009-159436089 22 1.37e-05 CGCCGTACAA TGACGTCA CACAGCGACT chr3:38206506-38206586 24 1.37e-05 GGTTACGCCG TGACGTCA CTCCAGAGGA chr17:40829281-40829361 45 1.37e-05 GGGGTGCTAG TGACGTCA CGGAAGCCCG chr7:55433934-55434014 63 1.37e-05 CCGCCAGGCG TGACGTCA CAGGCGCGCG chr14:32030559-32030639 22 1.37e-05 CGTTGCTCCG TGACGTCA TCACTCCGCG chr16:75657141-75657221 49 1.37e-05 AAGGCGGACG TGACGTCA CAAAGCGCCG chr9:132539523-132539603 22 1.37e-05 ATGACCGCAG TGACGTCA CCCGGGAGGC chr12:133022743-13302282 56 1.37e-05 CTCCTGTAGA TGACGTCA CCACAGTAAG chr18:23806271-23806351 35 1.37e-05 CCGTCCCCAG TGACGTCA CGGGCGCGGC chr7:23571643-23571723 25 1.37e-05 GGCGTCTCTG TGACGTCA CGAGGCTCCA chr7:30174232-30174312 53 1.37e-05 GCTCGCGCTG TGACGTCA CCGGGCTCGC chr17:7835466-7835546 24 1.37e-05 CGCGGGCGGG TGACGTCA TCGAGGCGAG chr12:10766173-10766253 17 1.37e-05 CGCCTTGCAG TGACGTCA TCGCGCGGAA chr1:6320120-6320200 46 1.37e-05 GGCCGGGGCG TGACGTCA CAGCTCCGGG chr20:30192128-30192208 38 1.37e-05 TATGAATGGG TGACGTCA CAGGCCTGGC chr7:39772934-39773014 35 1.37e-05 CCAGCTACCG TGACGTCA CGAGACCCCC chr14:55738809-55738889 40 1.37e-05 CGTGTGTCTG TGACGTCA GAAGATGGGT chr1:243265037-243265117 51 1.37e-05 CGCGCCCTTG TGACGTCA CGGAAGGCGC chr19:46009769-46009849 61 1.37e-05 ACCAAATCAG TGACGTCA CTCGGGGCGG chr14:50053228-50053308 19 1.37e-05 GCCCAGTTGA TGACGTCA CCATACCACA chr12:31882013-31882093 31 1.37e-05 TAGGTTTTTG TGACGTCA CACGGATTTT chr19:49164457-49164537 55 1.37e-05 TAGCACCCAA TGACGTCA TAAGAGCGTT chr7:140396442-140396522 13 1.37e-05 AGCGACTCTG TGACGTCA CGGGAGGCGC chr7:44646064-44646144 36 1.37e-05 CGCGGCTCTG TGACGTCA CGAATCGGTC chr14:23388096-23388176 32 1.37e-05 TTTCTGCCCG TGACGTCA GGGGGGAGGC chr4:120375787-120375867 48 1.37e-05 CGCGCCATTG TGACGTCA CGGAAGGCGC chr14:105219421-10521950 51 1.37e-05 CGCGCAGCTG TGACGTCA CGGCGTCGTT chr16:3285179-3285259 25 1.37e-05 TCTGCGGCTG TGACGTCA CAACCGGTGC chr9:100395594-100395674 53 1.37e-05 AGCTCGCTCG TGACGTCA CCAAGCTCCG chr7:5492772-5492852 53 1.37e-05 CAGCATGTGA TGACGTCA CTGTCACCCC chr18:2655138-2655218 17 1.37e-05 GGGGACGCTG TGACGTCA CAGAGCGCCC chr2:8144533-8144613 51 1.37e-05 CTAGTTCTGA TGACGTCA TAGGCTGATT chr16:89766723-89766803 28 1.37e-05 ACGTGCCCAG TGACGTCA TCGGCTTCCT chr6:44355167-44355247 24 1.37e-05 TGCCACTCGG TGACGTCA CGATCAATCC chr7:75795866-75795946 71 1.37e-05 CCCGCGCCTG TGACGTCA GC chr18:76829139-76829219 1 1.37e-05 . TGACGTCA TTGCCCGGAC chr19:56015258-56015338 24 1.37e-05 TCGCACCTCG TGACGTCA CAGGCGCGCT chr11:3818985-3819065 53 1.37e-05 GAGCGTGTCG TGACGTCA CACAGGGCCT chr6:53213772-53213852 17 1.37e-05 GGGCTGACCG TGACGTCA CAATGGCGCG chr11:95523546-95523626 21 1.37e-05 CGCTACCTTG TGACGTCA CCAGGGAAGA chr7:65235816-65235896 35 1.37e-05 GCGCCTTCGG TGACGTCA CAGGGGCGGG chr9:33001613-33001693 51 1.37e-05 TCGCGACCAG TGACGTCA CCAGCACCTC chr12:64616303-64616383 63 1.37e-05 TCAGCGCTGG TGACGTCA TGCAAACGTG chr19:36103552-36103632 55 1.37e-05 CGGCAACCGA TGACGTCA CTGTTGGCGC chr17:38136743-38136823 18 1.37e-05 CGGCAACTCG TGACGTCA TCTCGTCCCG chr4:170541640-170541720 33 1.37e-05 GTCAACGTAG TGACGTCA CGCGTCGACG chr2:28114101-28114181 70 1.37e-05 TTCCGTTCCA TGACGTCA GCA chr13:49821989-49822069 11 1.37e-05 CGCCTCTCTA TGACGTCA CACGAGGAGC chr7:137686977-137687057 27 1.37e-05 GGAGTGTCTG TGACGTCA CCGAGGAACT chr6:15248926-15249006 49 1.37e-05 GTTGTCATTG TGACGTCA CAAAGGGACG chr7:45808606-45808686 49 1.37e-05 GCGCCTTCCG TGACGTCA CAAGGGCGCG chr1:224180298-224180378 48 1.37e-05 CCCGCCCTTG TGACGTCA CGGAAGGCGC chr8:21967225-21967305 51 1.37e-05 GACAATCCGG TGACGTCA CGGAGGCCCG chr19:50862181-50862261 51 1.37e-05 AACCGTCATA TGACGTCA CTATGGCGTC chr11:77185401-77185481 46 1.37e-05 GCTTGCTGCG TGACGTCA TCGCGTCGCG chr2:74781530-74781610 49 1.37e-05 CTTGGGCATA TGACGTCA CGCGCAGCCA chr5:95297753-95297833 31 1.37e-05 TAATCATGTC TGACGTCA CGTCTGGTCG chr4:119512822-119512902 18 1.37e-05 GAGGCTTCCG TGACGTCA CAAGGGTGCG chr19:50979516-50979596 42 1.37e-05 GCGGGCTTTA TGACGTCA CACAAGAGCG chr14:68086437-68086517 28 1.37e-05 CAGAGTGGGG TGACGTCA TCGAAGGCAC chr19:17728312-17728392 15 1.37e-05 TCCAGGCCTG TGACGTCA GAGGCCCCGC chr6:139456066-139456146 48 1.37e-05 GCGCGGGGCG TGACGTCA CGCGGGCGGT chr2:19548149-19548229 60 1.37e-05 GAGGCCTCTG TGACGTCA CGGTGTCTGC chr1:202522920-202523000 42 2.38e-05 TTGCCTCTTC TGATGTCA CTTCCTGGCT chr5:78810426-78810506 27 2.38e-05 GTGCGGGGGA TGATGTCA CGCGGCCGGA chr12:131249248-13124932 61 2.38e-05 acagtgttga tgatgtca tggtgctgat chr22:38576158-38576238 67 2.38e-05 TATCTCTTAG TGATGTCA TTCTGC chr17:1196881-1196961 58 2.38e-05 ttgggtttga tgatgtca tgggctgggt chr5:137673177-137673257 18 2.38e-05 GAACCGCCTA TGATGTCA TAATCACAAT chr2:2577813-2577893 17 2.38e-05 ggtatagtag tgatgtca tggtgacatc chr1:4052256-4052336 67 2.38e-05 atgggagagg tgatgtca tggaga chr17:79093597-79093677 49 2.38e-05 GCTCCTCCCA TGATGTCA CACATTAGGC chr8:145682209-145682289 50 3.37e-05 TCATGGGGGG TGACATCA CGGAATGACA chr17:76554590-76554670 50 3.37e-05 TGCATGTGTA TGACATCA TTGTCATCAC chr2:68290122-68290202 14 7.50e-05 CGGGCAACGA TGACGACA ATGACGCGCC chr7:6488065-6488145 1 7.50e-05 . tgacctca agtgatccgc chr10:75639463-75639543 61 7.50e-05 GGTACTGATG TGACGACA GGCGGGCGGC chr1:156698651-156698731 51 7.50e-05 TCGCGACCTG TGACGTCT GGGGGGCGCC chr8:144536788-144536868 22 7.50e-05 ctcgatctct tgacctca tgatccacct chr19:17462815-17462895 68 7.50e-05 TATCTCTTCG TGACGTCT ACATG chr11:4115967-4116047 37 8.49e-05 CAGCGTCGAG TAACGTCA TTCGAACCCC chr12:58138352-58138432 58 9.85e-05 GGCGTCATCG TGAGGTCA CTGCAGAACA chr1:70820637-70820717 68 1.55e-04 GAATGCAGAA TGACGCCA CGGCA chr1:228296935-228297015 56 1.55e-04 CTGCAGCCCA CGACGTCA CTGGCAGGCG chr7:65958507-65958587 36 1.55e-04 AGCGCCACTG TGACGTCG CCGAAGGCCG -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGACGTCA MEME-1 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr4:57253606-57253686 1.4e-05 71_[+1]_1 chr15:91537885-91537965 1.4e-05 49_[+1]_23 chr2:43823223-43823303 1.4e-05 54_[+1]_18 chr19:11646978-11647058 1.4e-05 15_[+1]_57 chr1:39456869-39456949 1.4e-05 40_[+1]_32 chr19:56825967-56826047 1.4e-05 41_[+1]_31 chr3:99536615-99536695 1.4e-05 61_[+1]_11 chr4:113558039-113558119 1.4e-05 16_[+1]_56 chr16:68057124-68057204 1.4e-05 13_[+1]_59 chr1:168147948-168148028 1.4e-05 20_[+1]_52 chr7:23221562-23221642 1.4e-05 31_[+1]_41 chr17:26662482-26662562 1.4e-05 15_[+1]_57 chr16:86588813-86588893 1.4e-05 27_[+1]_45 chr1:936243-936323 1.4e-05 54_[+1]_18 chr17:33914242-33914322 1.4e-05 35_[+1]_37 chr12:132628914-13262899 1.4e-05 62_[+1]_10 chr19:46135924-46136004 1.4e-05 62_[+1]_10 chr11:809824-809904 1.4e-05 49_[+1]_23 chr4:104119584-104119664 1.4e-05 22_[+1]_50 chr18:77866838-77866918 1.4e-05 50_[+1]_22 chr7:100464925-100465005 1.4e-05 23_[+1]_49 chr3:58291936-58292016 1.4e-05 28_[+1]_44 chr19:55517486-55517566 1.4e-05 60_[+1]_12 chr6:30028915-30028995 1.4e-05 51_[+1]_21 chr1:1790231-1790311 1.4e-05 22_[+1]_50 chr15:42840942-42841022 1.4e-05 48_[+1]_24 chr7:124569881-124569961 1.4e-05 13_[+1]_59 chr7:66309958-66310038 1.4e-05 16_[+1]_56 chr19:51014783-51014863 1.4e-05 33_[+1]_39 chr8:117768082-117768162 1.4e-05 18_[+1]_54 chr19:9546217-9546297 1.4e-05 41_[+1]_31 chr19:51506089-51506169 1.4e-05 34_[+1]_38 chr3:128598287-128598367 1.4e-05 17_[+1]_55 chr1:110527275-110527355 1.4e-05 21_[+1]_51 chr6:37400923-37401003 1.4e-05 49_[+1]_23 chr19:2962161-2962241 1.4e-05 37_[+1]_35 chr12:56521642-56521722 1.4e-05 46_[+1]_26 chr9:111696365-111696445 1.4e-05 49_[+1]_23 chr1:714044-714124 1.4e-05 48_[+1]_24 chr19:8454834-8454914 1.4e-05 23_[+1]_49 chr6:31939720-31939800 1.4e-05 20_[+1]_52 chr17:56744256-56744336 1.4e-05 23_[+1]_49 chr1:9489019-9489099 1.4e-05 23_[+1]_49 chr7:129592772-129592852 1.4e-05 50_[+1]_22 chr9:125027101-125027181 1.4e-05 41_[+1]_31 chr1:32110409-32110489 1.4e-05 64_[+1]_8 chr12:120729911-12072999 1.4e-05 29_[+1]_43 chr19:36119873-36119953 1.4e-05 40_[+1]_32 chr3:140660528-140660608 1.4e-05 32_[+1]_40 chr5:159436009-159436089 1.4e-05 21_[+1]_51 chr3:38206506-38206586 1.4e-05 23_[+1]_49 chr17:40829281-40829361 1.4e-05 44_[+1]_28 chr7:55433934-55434014 1.4e-05 62_[+1]_10 chr14:32030559-32030639 1.4e-05 21_[+1]_51 chr16:75657141-75657221 1.4e-05 48_[+1]_24 chr9:132539523-132539603 1.4e-05 21_[+1]_51 chr12:133022743-13302282 1.4e-05 55_[+1]_17 chr18:23806271-23806351 1.4e-05 34_[+1]_38 chr7:23571643-23571723 1.4e-05 24_[+1]_48 chr7:30174232-30174312 1.4e-05 52_[+1]_20 chr17:7835466-7835546 1.4e-05 23_[+1]_49 chr12:10766173-10766253 1.4e-05 16_[+1]_56 chr1:6320120-6320200 1.4e-05 45_[+1]_27 chr20:30192128-30192208 1.4e-05 37_[+1]_35 chr7:39772934-39773014 1.4e-05 34_[+1]_38 chr14:55738809-55738889 1.4e-05 39_[+1]_33 chr1:243265037-243265117 1.4e-05 50_[+1]_22 chr19:46009769-46009849 1.4e-05 60_[+1]_12 chr14:50053228-50053308 1.4e-05 18_[+1]_54 chr12:31882013-31882093 1.4e-05 30_[+1]_42 chr19:49164457-49164537 1.4e-05 54_[+1]_18 chr7:140396442-140396522 1.4e-05 12_[+1]_60 chr7:44646064-44646144 1.4e-05 35_[+1]_37 chr14:23388096-23388176 1.4e-05 31_[+1]_41 chr4:120375787-120375867 1.4e-05 47_[+1]_25 chr14:105219421-10521950 1.4e-05 50_[+1]_22 chr16:3285179-3285259 1.4e-05 24_[+1]_48 chr9:100395594-100395674 1.4e-05 52_[+1]_20 chr7:5492772-5492852 1.4e-05 52_[+1]_20 chr18:2655138-2655218 1.4e-05 16_[+1]_56 chr2:8144533-8144613 1.4e-05 50_[+1]_22 chr16:89766723-89766803 1.4e-05 27_[+1]_45 chr6:44355167-44355247 1.4e-05 23_[+1]_49 chr7:75795866-75795946 1.4e-05 70_[+1]_2 chr18:76829139-76829219 1.4e-05 [+1]_72 chr19:56015258-56015338 1.4e-05 23_[+1]_49 chr11:3818985-3819065 1.4e-05 52_[+1]_20 chr6:53213772-53213852 1.4e-05 16_[+1]_56 chr11:95523546-95523626 1.4e-05 20_[+1]_52 chr7:65235816-65235896 1.4e-05 34_[+1]_38 chr9:33001613-33001693 1.4e-05 50_[+1]_22 chr12:64616303-64616383 1.4e-05 62_[+1]_10 chr19:36103552-36103632 1.4e-05 54_[+1]_18 chr17:38136743-38136823 1.4e-05 17_[+1]_55 chr4:170541640-170541720 1.4e-05 32_[+1]_40 chr2:28114101-28114181 1.4e-05 69_[+1]_3 chr13:49821989-49822069 1.4e-05 10_[+1]_62 chr7:137686977-137687057 1.4e-05 26_[+1]_46 chr6:15248926-15249006 1.4e-05 48_[+1]_24 chr7:45808606-45808686 1.4e-05 48_[+1]_24 chr1:224180298-224180378 1.4e-05 47_[+1]_25 chr8:21967225-21967305 1.4e-05 50_[+1]_22 chr19:50862181-50862261 1.4e-05 50_[+1]_22 chr11:77185401-77185481 1.4e-05 45_[+1]_27 chr2:74781530-74781610 1.4e-05 48_[+1]_24 chr5:95297753-95297833 1.4e-05 30_[+1]_42 chr4:119512822-119512902 1.4e-05 17_[+1]_55 chr19:50979516-50979596 1.4e-05 41_[+1]_31 chr14:68086437-68086517 1.4e-05 27_[+1]_45 chr19:17728312-17728392 1.4e-05 14_[+1]_58 chr6:139456066-139456146 1.4e-05 47_[+1]_25 chr2:19548149-19548229 1.4e-05 59_[+1]_13 chr1:202522920-202523000 2.4e-05 41_[+1]_31 chr5:78810426-78810506 2.4e-05 26_[+1]_46 chr12:131249248-13124932 2.4e-05 60_[+1]_12 chr22:38576158-38576238 2.4e-05 66_[+1]_6 chr17:1196881-1196961 2.4e-05 57_[+1]_15 chr5:137673177-137673257 2.4e-05 17_[+1]_55 chr2:2577813-2577893 2.4e-05 16_[+1]_56 chr1:4052256-4052336 2.4e-05 66_[+1]_6 chr17:79093597-79093677 2.4e-05 48_[+1]_24 chr8:145682209-145682289 3.4e-05 49_[+1]_23 chr17:76554590-76554670 3.4e-05 49_[+1]_23 chr2:68290122-68290202 7.5e-05 13_[+1]_59 chr7:6488065-6488145 7.5e-05 [+1]_72 chr10:75639463-75639543 7.5e-05 60_[+1]_12 chr1:156698651-156698731 7.5e-05 50_[+1]_22 chr8:144536788-144536868 7.5e-05 21_[+1]_51 chr19:17462815-17462895 7.5e-05 67_[+1]_5 chr11:4115967-4116047 8.5e-05 36_[+1]_36 chr12:58138352-58138432 9.9e-05 57_[+1]_15 chr1:70820637-70820717 0.00016 67_[+1]_5 chr1:228296935-228297015 0.00016 55_[+1]_17 chr7:65958507-65958587 0.00016 35_[+1]_37 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGACGTCA MEME-1 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF TGACGTCA width=8 seqs=134 chr4:57253606-57253686 ( 72) TGACGTCA 1 chr15:91537885-91537965 ( 50) TGACGTCA 1 chr2:43823223-43823303 ( 55) TGACGTCA 1 chr19:11646978-11647058 ( 16) TGACGTCA 1 chr1:39456869-39456949 ( 41) TGACGTCA 1 chr19:56825967-56826047 ( 42) TGACGTCA 1 chr3:99536615-99536695 ( 62) TGACGTCA 1 chr4:113558039-113558119 ( 17) TGACGTCA 1 chr16:68057124-68057204 ( 14) TGACGTCA 1 chr1:168147948-168148028 ( 21) TGACGTCA 1 chr7:23221562-23221642 ( 32) TGACGTCA 1 chr17:26662482-26662562 ( 16) TGACGTCA 1 chr16:86588813-86588893 ( 28) TGACGTCA 1 chr1:936243-936323 ( 55) TGACGTCA 1 chr17:33914242-33914322 ( 36) TGACGTCA 1 chr12:132628914-13262899 ( 63) TGACGTCA 1 chr19:46135924-46136004 ( 63) TGACGTCA 1 chr11:809824-809904 ( 50) TGACGTCA 1 chr4:104119584-104119664 ( 23) TGACGTCA 1 chr18:77866838-77866918 ( 51) TGACGTCA 1 chr7:100464925-100465005 ( 24) TGACGTCA 1 chr3:58291936-58292016 ( 29) TGACGTCA 1 chr19:55517486-55517566 ( 61) TGACGTCA 1 chr6:30028915-30028995 ( 52) TGACGTCA 1 chr1:1790231-1790311 ( 23) TGACGTCA 1 chr15:42840942-42841022 ( 49) TGACGTCA 1 chr7:124569881-124569961 ( 14) TGACGTCA 1 chr7:66309958-66310038 ( 17) TGACGTCA 1 chr19:51014783-51014863 ( 34) TGACGTCA 1 chr8:117768082-117768162 ( 19) TGACGTCA 1 chr19:9546217-9546297 ( 42) TGACGTCA 1 chr19:51506089-51506169 ( 35) TGACGTCA 1 chr3:128598287-128598367 ( 18) TGACGTCA 1 chr1:110527275-110527355 ( 22) TGACGTCA 1 chr6:37400923-37401003 ( 50) TGACGTCA 1 chr19:2962161-2962241 ( 38) TGACGTCA 1 chr12:56521642-56521722 ( 47) TGACGTCA 1 chr9:111696365-111696445 ( 50) TGACGTCA 1 chr1:714044-714124 ( 49) TGACGTCA 1 chr19:8454834-8454914 ( 24) TGACGTCA 1 chr6:31939720-31939800 ( 21) TGACGTCA 1 chr17:56744256-56744336 ( 24) TGACGTCA 1 chr1:9489019-9489099 ( 24) TGACGTCA 1 chr7:129592772-129592852 ( 51) TGACGTCA 1 chr9:125027101-125027181 ( 42) TGACGTCA 1 chr1:32110409-32110489 ( 65) TGACGTCA 1 chr12:120729911-12072999 ( 30) TGACGTCA 1 chr19:36119873-36119953 ( 41) TGACGTCA 1 chr3:140660528-140660608 ( 33) TGACGTCA 1 chr5:159436009-159436089 ( 22) TGACGTCA 1 chr3:38206506-38206586 ( 24) TGACGTCA 1 chr17:40829281-40829361 ( 45) TGACGTCA 1 chr7:55433934-55434014 ( 63) TGACGTCA 1 chr14:32030559-32030639 ( 22) TGACGTCA 1 chr16:75657141-75657221 ( 49) TGACGTCA 1 chr9:132539523-132539603 ( 22) TGACGTCA 1 chr12:133022743-13302282 ( 56) TGACGTCA 1 chr18:23806271-23806351 ( 35) TGACGTCA 1 chr7:23571643-23571723 ( 25) TGACGTCA 1 chr7:30174232-30174312 ( 53) TGACGTCA 1 chr17:7835466-7835546 ( 24) TGACGTCA 1 chr12:10766173-10766253 ( 17) TGACGTCA 1 chr1:6320120-6320200 ( 46) TGACGTCA 1 chr20:30192128-30192208 ( 38) TGACGTCA 1 chr7:39772934-39773014 ( 35) TGACGTCA 1 chr14:55738809-55738889 ( 40) TGACGTCA 1 chr1:243265037-243265117 ( 51) TGACGTCA 1 chr19:46009769-46009849 ( 61) TGACGTCA 1 chr14:50053228-50053308 ( 19) TGACGTCA 1 chr12:31882013-31882093 ( 31) TGACGTCA 1 chr19:49164457-49164537 ( 55) TGACGTCA 1 chr7:140396442-140396522 ( 13) TGACGTCA 1 chr7:44646064-44646144 ( 36) TGACGTCA 1 chr14:23388096-23388176 ( 32) TGACGTCA 1 chr4:120375787-120375867 ( 48) TGACGTCA 1 chr14:105219421-10521950 ( 51) TGACGTCA 1 chr16:3285179-3285259 ( 25) TGACGTCA 1 chr9:100395594-100395674 ( 53) TGACGTCA 1 chr7:5492772-5492852 ( 53) TGACGTCA 1 chr18:2655138-2655218 ( 17) TGACGTCA 1 chr2:8144533-8144613 ( 51) TGACGTCA 1 chr16:89766723-89766803 ( 28) TGACGTCA 1 chr6:44355167-44355247 ( 24) TGACGTCA 1 chr7:75795866-75795946 ( 71) TGACGTCA 1 chr18:76829139-76829219 ( 1) TGACGTCA 1 chr19:56015258-56015338 ( 24) TGACGTCA 1 chr11:3818985-3819065 ( 53) TGACGTCA 1 chr6:53213772-53213852 ( 17) TGACGTCA 1 chr11:95523546-95523626 ( 21) TGACGTCA 1 chr7:65235816-65235896 ( 35) TGACGTCA 1 chr9:33001613-33001693 ( 51) TGACGTCA 1 chr12:64616303-64616383 ( 63) TGACGTCA 1 chr19:36103552-36103632 ( 55) TGACGTCA 1 chr17:38136743-38136823 ( 18) TGACGTCA 1 chr4:170541640-170541720 ( 33) TGACGTCA 1 chr2:28114101-28114181 ( 70) TGACGTCA 1 chr13:49821989-49822069 ( 11) TGACGTCA 1 chr7:137686977-137687057 ( 27) TGACGTCA 1 chr6:15248926-15249006 ( 49) TGACGTCA 1 chr7:45808606-45808686 ( 49) TGACGTCA 1 chr1:224180298-224180378 ( 48) TGACGTCA 1 chr8:21967225-21967305 ( 51) TGACGTCA 1 chr19:50862181-50862261 ( 51) TGACGTCA 1 chr11:77185401-77185481 ( 46) TGACGTCA 1 chr2:74781530-74781610 ( 49) TGACGTCA 1 chr5:95297753-95297833 ( 31) TGACGTCA 1 chr4:119512822-119512902 ( 18) TGACGTCA 1 chr19:50979516-50979596 ( 42) TGACGTCA 1 chr14:68086437-68086517 ( 28) TGACGTCA 1 chr19:17728312-17728392 ( 15) TGACGTCA 1 chr6:139456066-139456146 ( 48) TGACGTCA 1 chr2:19548149-19548229 ( 60) TGACGTCA 1 chr1:202522920-202523000 ( 42) TGATGTCA 1 chr5:78810426-78810506 ( 27) TGATGTCA 1 chr12:131249248-13124932 ( 61) TGATGTCA 1 chr22:38576158-38576238 ( 67) TGATGTCA 1 chr17:1196881-1196961 ( 58) TGATGTCA 1 chr5:137673177-137673257 ( 18) TGATGTCA 1 chr2:2577813-2577893 ( 17) TGATGTCA 1 chr1:4052256-4052336 ( 67) TGATGTCA 1 chr17:79093597-79093677 ( 49) TGATGTCA 1 chr8:145682209-145682289 ( 50) TGACATCA 1 chr17:76554590-76554670 ( 50) TGACATCA 1 chr2:68290122-68290202 ( 14) TGACGACA 1 chr7:6488065-6488145 ( 1) TGACCTCA 1 chr10:75639463-75639543 ( 61) TGACGACA 1 chr1:156698651-156698731 ( 51) TGACGTCT 1 chr8:144536788-144536868 ( 22) TGACCTCA 1 chr19:17462815-17462895 ( 68) TGACGTCT 1 chr11:4115967-4116047 ( 37) TAACGTCA 1 chr12:58138352-58138432 ( 58) TGAGGTCA 1 chr1:70820637-70820717 ( 68) TGACGCCA 1 chr1:228296935-228297015 ( 56) CGACGTCA 1 chr7:65958507-65958587 ( 36) TGACGTCG 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGACGTCA MEME-1 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 8.43997 E= 1.1e-263 -1371 -528 -1371 222 -479 -1371 178 -1371 227 -1371 -1371 -1371 -1371 167 -527 -166 -379 -428 175 -1371 -379 -528 -1371 220 -1371 178 -1371 -1371 224 -1371 -527 -383 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGACGTCA MEME-1 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 134 E= 1.1e-263 0.000000 0.007463 0.000000 0.992537 0.007463 0.000000 0.992537 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.925373 0.007463 0.067164 0.014925 0.014925 0.970149 0.000000 0.014925 0.007463 0.000000 0.977612 0.000000 1.000000 0.000000 0.000000 0.977612 0.000000 0.007463 0.014925 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGACGTCA MEME-1 regular expression -------------------------------------------------------------------------------- TGACGTCA -------------------------------------------------------------------------------- Time 4.64 secs. ******************************************************************************** ******************************************************************************** MOTIF TGACGTCA MEME-2 width = 8 sites = 34 llr = 295 E-value = 1.2e-006 ******************************************************************************** -------------------------------------------------------------------------------- Motif TGACGTCA MEME-2 Description -------------------------------------------------------------------------------- Simplified A ::9:1::7 pos.-specific C :1:9:1a: probability G :91:9::3 matrix T a::1:9:: bits 2.3 * 2.0 * 1.8 * ** 1.6 * * ** Relative 1.4 *** **** Entropy 1.1 ******** (12.5 bits) 0.9 ******** 0.7 ******** 0.5 ******** 0.2 ******** 0.0 -------- Multilevel TGACGTCA consensus G sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGACGTCA MEME-2 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr1:936243-936323 11 1.37e-05 AGCGGGCTGG TGACGTCA CCAGGCACCC chr17:33914242-33914322 13 1.37e-05 CGCACCCCGA TGACGTCA CGCGGCGACG chr1:714044-714124 24 1.37e-05 CCCGCCCTTG TGACGTCA CGGAAGGCGC chr7:129592772-129592852 37 1.37e-05 CTGGGCGCCG TGACGTCA CCTCTGTGAC chr12:133022743-13302282 5 1.37e-05 TATA TGACGTCA CCGCCGTAAG chr9:33001613-33001693 20 1.37e-05 CGCTGCGGGA TGACGTCA GAGGCCGGCT chr2:74781530-74781610 30 1.37e-05 GCTTTCACTC TGACGTCA CCTTGGGCAT chr4:119512822-119512902 43 1.37e-05 GCGCCCTCCG TGACGTCA CAAGGGCGCG chr19:50979516-50979596 15 1.37e-05 ACGCGCACTG TGACGTCA TGATGCGGAG chr6:139456066-139456146 11 1.37e-05 GACGCCTGGA TGACGTCA CTCGAGGTGG chr12:132628914-13262899 38 3.29e-05 CGCGTAGAGA TGACGTCG GGTTCTACGC chr1:243265037-243265117 1 3.29e-05 . TGACGTCG CCAAAGGCCC chr2:2577813-2577893 47 3.29e-05 ggtgatgtgg tgacgtcg tggtgatgtg chr2:28114101-28114181 26 3.29e-05 GTGCGCTGTA TGACGTCG ACGTGACGCA chr1:224180298-224180378 73 3.29e-05 CGCGCTCTTG TGACGTCG chr12:131249248-13124932 44 4.30e-05 gtggtgttga tgatgtca cagtgttgat chr6:53213772-53213852 73 4.30e-05 TCAAGCGCTA TGATGTCA chr1:4052256-4052336 50 4.30e-05 aaaggggaga tgatgtca tgggagaggt chr8:145682209-145682289 63 5.29e-05 CATCACGGAA TGACATCA CAGAGATGAC chr17:76554590-76554670 6 5.29e-05 GTGGA TGACATCA CCCTCATGGG chr19:51014783-51014863 4 7.21e-05 CGA TGGCGTCA TGCGCGGTGC chr12:58138352-58138432 47 7.21e-05 AACAAAACAA TGGCGTCA TCGTGAGGTC chr19:50862181-50862261 62 7.21e-05 GACGTCACTA TGGCGTCA TGGTGATGGC chr14:23388096-23388176 13 9.08e-05 AATCTCTTCG TGACGCCA TTTTCTGCCC chr4:120375787-120375867 73 9.08e-05 CGCGCTCTTG TGACGCCA chr11:77185401-77185481 10 9.08e-05 ATCGGCGCG TGACGCCA GAGGCTGGGG chr5:78810426-78810506 4 1.05e-04 AGC TCACGTCA CCGAGGTGCG chr4:170541640-170541720 19 1.05e-04 GAACGGCCGT TCACGTCA ACGTAGTGAC chr14:55738809-55738889 8 1.29e-04 TCCACGA TGAAGTCA TAGGGCTGTG chr17:1196881-1196961 36 1.29e-04 ttgtgtttga tgatgtcg caggttgggt chr1:147737229-147737309 21 1.52e-04 ACGAAGAGGG TGACATCG CGAGGCTGAG chr19:2962161-2962241 57 1.52e-04 cttatgtaaa ttacgtca acgaagcGCT chr7:75795866-75795946 21 1.52e-04 AGCGTCACTG TGACATCG CCGAAGGCCG chr2:11607-11687 5 1.86e-04 ctgc tggcgtcg gagcattgca -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGACGTCA MEME-2 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr1:936243-936323 1.4e-05 10_[+2]_62 chr17:33914242-33914322 1.4e-05 12_[+2]_60 chr1:714044-714124 1.4e-05 23_[+2]_49 chr7:129592772-129592852 1.4e-05 36_[+2]_36 chr12:133022743-13302282 1.4e-05 4_[+2]_68 chr9:33001613-33001693 1.4e-05 19_[+2]_53 chr2:74781530-74781610 1.4e-05 29_[+2]_43 chr4:119512822-119512902 1.4e-05 42_[+2]_30 chr19:50979516-50979596 1.4e-05 14_[+2]_58 chr6:139456066-139456146 1.4e-05 10_[+2]_62 chr12:132628914-13262899 3.3e-05 37_[+2]_35 chr1:243265037-243265117 3.3e-05 [+2]_72 chr2:2577813-2577893 3.3e-05 46_[+2]_26 chr2:28114101-28114181 3.3e-05 25_[+2]_47 chr1:224180298-224180378 3.3e-05 72_[+2] chr12:131249248-13124932 4.3e-05 43_[+2]_29 chr6:53213772-53213852 4.3e-05 72_[+2] chr1:4052256-4052336 4.3e-05 49_[+2]_23 chr8:145682209-145682289 5.3e-05 62_[+2]_10 chr17:76554590-76554670 5.3e-05 5_[+2]_67 chr19:51014783-51014863 7.2e-05 3_[+2]_69 chr12:58138352-58138432 7.2e-05 46_[+2]_26 chr19:50862181-50862261 7.2e-05 61_[+2]_11 chr14:23388096-23388176 9.1e-05 12_[+2]_60 chr4:120375787-120375867 9.1e-05 72_[+2] chr11:77185401-77185481 9.1e-05 9_[+2]_63 chr5:78810426-78810506 0.0001 3_[+2]_69 chr4:170541640-170541720 0.0001 18_[+2]_54 chr14:55738809-55738889 0.00013 7_[+2]_65 chr17:1196881-1196961 0.00013 35_[+2]_37 chr1:147737229-147737309 0.00015 20_[+2]_52 chr19:2962161-2962241 0.00015 56_[+2]_16 chr7:75795866-75795946 0.00015 20_[+2]_52 chr2:11607-11687 0.00019 4_[+2]_68 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGACGTCA MEME-2 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF TGACGTCA width=8 seqs=34 chr1:936243-936323 ( 11) TGACGTCA 1 chr17:33914242-33914322 ( 13) TGACGTCA 1 chr1:714044-714124 ( 24) TGACGTCA 1 chr7:129592772-129592852 ( 37) TGACGTCA 1 chr12:133022743-13302282 ( 5) TGACGTCA 1 chr9:33001613-33001693 ( 20) TGACGTCA 1 chr2:74781530-74781610 ( 30) TGACGTCA 1 chr4:119512822-119512902 ( 43) TGACGTCA 1 chr19:50979516-50979596 ( 15) TGACGTCA 1 chr6:139456066-139456146 ( 11) TGACGTCA 1 chr12:132628914-13262899 ( 38) TGACGTCG 1 chr1:243265037-243265117 ( 1) TGACGTCG 1 chr2:2577813-2577893 ( 47) TGACGTCG 1 chr2:28114101-28114181 ( 26) TGACGTCG 1 chr1:224180298-224180378 ( 73) TGACGTCG 1 chr12:131249248-13124932 ( 44) TGATGTCA 1 chr6:53213772-53213852 ( 73) TGATGTCA 1 chr1:4052256-4052336 ( 50) TGATGTCA 1 chr8:145682209-145682289 ( 63) TGACATCA 1 chr17:76554590-76554670 ( 6) TGACATCA 1 chr19:51014783-51014863 ( 4) TGGCGTCA 1 chr12:58138352-58138432 ( 47) TGGCGTCA 1 chr19:50862181-50862261 ( 62) TGGCGTCA 1 chr14:23388096-23388176 ( 13) TGACGCCA 1 chr4:120375787-120375867 ( 73) TGACGCCA 1 chr11:77185401-77185481 ( 10) TGACGCCA 1 chr5:78810426-78810506 ( 4) TCACGTCA 1 chr4:170541640-170541720 ( 19) TCACGTCA 1 chr14:55738809-55738889 ( 8) TGAAGTCA 1 chr17:1196881-1196961 ( 36) TGATGTCG 1 chr1:147737229-147737309 ( 21) TGACATCG 1 chr19:2962161-2962241 ( 57) TTACGTCA 1 chr7:75795866-75795946 ( 21) TGACATCG 1 chr2:11607-11687 ( 5) TGGCGTCG 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGACGTCA MEME-2 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 10.4321 E= 1.2e-006 -1173 -1173 -1173 223 -1173 -231 166 -285 209 -1173 -130 -1173 -281 155 -1173 -86 -81 -1173 161 -1173 -1173 -172 -1173 210 -1173 178 -1173 -1173 183 -1173 -13 -1173 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGACGTCA MEME-2 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 34 E= 1.2e-006 0.000000 0.000000 0.000000 1.000000 0.000000 0.058824 0.911765 0.029412 0.882353 0.000000 0.117647 0.000000 0.029412 0.852941 0.000000 0.117647 0.117647 0.000000 0.882353 0.000000 0.000000 0.088235 0.000000 0.911765 0.000000 1.000000 0.000000 0.000000 0.735294 0.000000 0.264706 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGACGTCA MEME-2 regular expression -------------------------------------------------------------------------------- TGACGTC[AG] -------------------------------------------------------------------------------- Time 8.13 secs. ******************************************************************************** ******************************************************************************** MOTIF AMARAAAA MEME-3 width = 8 sites = 17 llr = 170 E-value = 2.2e-003 ******************************************************************************** -------------------------------------------------------------------------------- Motif AMARAAAA MEME-3 Description -------------------------------------------------------------------------------- Simplified A a5a6a99a pos.-specific C :4:::11: probability G :::4:::: matrix T :1:::::: bits 2.3 * * * * 2.0 * * * * 1.8 * * * * 1.6 * * **** Relative 1.4 * * **** Entropy 1.1 * ****** (14.5 bits) 0.9 ******** 0.7 ******** 0.5 ******** 0.2 ******** 0.0 -------- Multilevel AAAAAAAA consensus C G sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AMARAAAA MEME-3 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr17:49010940-49011020 34 3.37e-06 tatcttggaa aaaaaaaa aaGAGGAGGA chr7:100464925-100465005 72 3.37e-06 AGGAAGAGGA AAAAAAAA A chr6:28756797-28756877 48 3.37e-06 aactaaagta aaaaaaaa caaaaaacaa chr19:47616923-47617003 41 3.37e-06 CGGAGAGGGA AAAAAAAA ATAACCGAAA chr11:3465439-3465519 34 8.11e-06 CACCAATGAG ACAAAAAA ACCACAATTA chr10:43876161-43876241 34 8.11e-06 acaaaacaaa acaaaaaa accttacatt chr10:74397398-74397478 35 8.11e-06 gtgggttgcc acaaaaaa gcatatcctt chr6:7119748-7119828 16 1.28e-05 gggtgagagg aaagaaaa agcgtcagaa chr12:132344963-13234504 34 1.28e-05 agagagagag aaagaaaa gaaagagaag chr1:204675712-204675792 62 1.28e-05 ggcgagtaga aaagaaaa cgagagcgga chr1:4067797-4067877 33 1.94e-05 agatacagag acagaaaa agggaagtga chr1:16872470-16872550 62 1.94e-05 CTGCAGGATA ACAGAAAA CAGTATCCAC chr1:1790231-1790311 67 2.29e-05 ggctgctgtg ataaaaaa gcaagc chr1:17004730-17004810 23 3.24e-05 TAGCGAAGTG AAAAACAA CCACgtgcag chr6:3002421-3002501 13 4.57e-05 AGCATTTCAT ACAAACAA CATGATTTCG chr12:58138352-58138432 38 4.57e-05 TGACGCAATA ACAAAACA ATGGCGTCAT chr3:140660528-140660608 13 6.38e-05 GGATCACGTG AAAGAACA CTGCAGAGTG -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AMARAAAA MEME-3 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr17:49010940-49011020 3.4e-06 33_[+3]_39 chr7:100464925-100465005 3.4e-06 71_[+3]_1 chr6:28756797-28756877 3.4e-06 47_[+3]_25 chr19:47616923-47617003 3.4e-06 40_[+3]_32 chr11:3465439-3465519 8.1e-06 33_[+3]_39 chr10:43876161-43876241 8.1e-06 33_[+3]_39 chr10:74397398-74397478 8.1e-06 34_[+3]_38 chr6:7119748-7119828 1.3e-05 15_[+3]_57 chr12:132344963-13234504 1.3e-05 33_[+3]_39 chr1:204675712-204675792 1.3e-05 61_[+3]_11 chr1:4067797-4067877 1.9e-05 32_[+3]_40 chr1:16872470-16872550 1.9e-05 61_[+3]_11 chr1:1790231-1790311 2.3e-05 66_[+3]_6 chr1:17004730-17004810 3.2e-05 22_[+3]_50 chr6:3002421-3002501 4.6e-05 12_[+3]_60 chr12:58138352-58138432 4.6e-05 37_[+3]_35 chr3:140660528-140660608 6.4e-05 12_[+3]_60 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AMARAAAA MEME-3 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF AMARAAAA width=8 seqs=17 chr17:49010940-49011020 ( 34) AAAAAAAA 1 chr7:100464925-100465005 ( 72) AAAAAAAA 1 chr6:28756797-28756877 ( 48) AAAAAAAA 1 chr19:47616923-47617003 ( 41) AAAAAAAA 1 chr11:3465439-3465519 ( 34) ACAAAAAA 1 chr10:43876161-43876241 ( 34) ACAAAAAA 1 chr10:74397398-74397478 ( 35) ACAAAAAA 1 chr6:7119748-7119828 ( 16) AAAGAAAA 1 chr12:132344963-13234504 ( 34) AAAGAAAA 1 chr1:204675712-204675792 ( 62) AAAGAAAA 1 chr1:4067797-4067877 ( 33) ACAGAAAA 1 chr1:16872470-16872550 ( 62) ACAGAAAA 1 chr1:1790231-1790311 ( 67) ATAAAAAA 1 chr1:17004730-17004810 ( 23) AAAAACAA 1 chr6:3002421-3002501 ( 13) ACAAACAA 1 chr12:58138352-58138432 ( 38) ACAAAACA 1 chr3:140660528-140660608 ( 13) AAAGAACA 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AMARAAAA MEME-3 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 11.8333 E= 2.2e-003 227 -1073 -1073 -1073 136 50 -1073 -185 227 -1073 -1073 -1073 165 -1073 29 -1073 227 -1073 -1073 -1073 209 -131 -1073 -1073 209 -131 -1073 -1073 227 -1073 -1073 -1073 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AMARAAAA MEME-3 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 17 E= 2.2e-003 1.000000 0.000000 0.000000 0.000000 0.529412 0.411765 0.000000 0.058824 1.000000 0.000000 0.000000 0.000000 0.647059 0.000000 0.352941 0.000000 1.000000 0.000000 0.000000 0.000000 0.882353 0.117647 0.000000 0.000000 0.882353 0.117647 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AMARAAAA MEME-3 regular expression -------------------------------------------------------------------------------- A[AC]A[AG]AAAA -------------------------------------------------------------------------------- Time 11.90 secs. ******************************************************************************** ******************************************************************************** MOTIF GTGTGTGT MEME-4 width = 8 sites = 13 llr = 128 E-value = 2.9e+003 ******************************************************************************** -------------------------------------------------------------------------------- Motif GTGTGTGT MEME-4 Description -------------------------------------------------------------------------------- Simplified A :::::::: pos.-specific C ::2::11: probability G a:8:a:91 matrix T :a:a:9:9 bits 2.3 * * 2.0 * * 1.8 ** *** * 1.6 ** *** * Relative 1.4 ** ***** Entropy 1.1 ******** (14.2 bits) 0.9 ******** 0.7 ******** 0.5 ******** 0.2 ******** 0.0 -------- Multilevel GTGTGTGT consensus sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GTGTGTGT MEME-4 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr6:43670450-43670530 29 1.44e-05 gtgtgtgtgt gtgtgtgt ttgtgtgtgt chr1:161067462-161067542 72 1.44e-05 ctctgtgtgt gtgtgtgt g chr1:203242454-203242534 55 1.44e-05 CTTACTCTGG GTGTGTGT GGACGGGCGT chr5:159624897-159624977 52 1.44e-05 gtgtgtgtgt gtgtgtgt gtgtatgtgt chr1:40840265-40840345 22 1.44e-05 gtgtgtgtgt gtgtgtgt gtgAGAGAGA chr17:38689738-38689818 67 1.44e-05 Ctgtgtgtgt gtgtgtgt gtgtgt chr11:85869980-85870060 54 1.44e-05 gtgtttgtgt gtgtgtgt gtgtgtACAC chr15:34807470-34807550 68 1.44e-05 ctctctgtgt gtgtgtgt gtgtg chr7:1546712-1546792 67 2.88e-05 CTCTTCTGGA GTCTGTGT GAATGA chr19:17462815-17462895 17 2.88e-05 AGTTCCCCAT GTCTGTGT GCGACGTGCT chr14:55738809-55738889 31 4.33e-05 CTGTGGGTCC GTGTGTCT GTGACGTCAG chr16:68057124-68057204 69 8.24e-05 GCTCAGTACG GTGTGTGG AGCT chr6:7119748-7119828 69 8.24e-05 ttggagagag gtgtgcgt ccag -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GTGTGTGT MEME-4 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr6:43670450-43670530 1.4e-05 28_[+4]_44 chr1:161067462-161067542 1.4e-05 71_[+4]_1 chr1:203242454-203242534 1.4e-05 54_[+4]_18 chr5:159624897-159624977 1.4e-05 51_[+4]_21 chr1:40840265-40840345 1.4e-05 21_[+4]_51 chr17:38689738-38689818 1.4e-05 66_[+4]_6 chr11:85869980-85870060 1.4e-05 53_[+4]_19 chr15:34807470-34807550 1.4e-05 67_[+4]_5 chr7:1546712-1546792 2.9e-05 66_[+4]_6 chr19:17462815-17462895 2.9e-05 16_[+4]_56 chr14:55738809-55738889 4.3e-05 30_[+4]_42 chr16:68057124-68057204 8.2e-05 68_[+4]_4 chr6:7119748-7119828 8.2e-05 68_[+4]_4 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GTGTGTGT MEME-4 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF GTGTGTGT width=8 seqs=13 chr6:43670450-43670530 ( 29) GTGTGTGT 1 chr1:161067462-161067542 ( 72) GTGTGTGT 1 chr1:203242454-203242534 ( 55) GTGTGTGT 1 chr5:159624897-159624977 ( 52) GTGTGTGT 1 chr1:40840265-40840345 ( 22) GTGTGTGT 1 chr17:38689738-38689818 ( 67) GTGTGTGT 1 chr11:85869980-85870060 ( 54) GTGTGTGT 1 chr15:34807470-34807550 ( 68) GTGTGTGT 1 chr7:1546712-1546792 ( 67) GTCTGTGT 1 chr19:17462815-17462895 ( 17) GTCTGTGT 1 chr14:55738809-55738889 ( 31) GTGTGTCT 1 chr16:68057124-68057204 ( 69) GTGTGTGG 1 chr6:7119748-7119828 ( 69) GTGTGCGT 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GTGTGTGT MEME-4 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 10.985 E= 2.9e+003 -1035 -1035 179 -1035 -1035 -1035 -1035 223 -1035 -92 155 -1035 -1035 -1035 -1035 223 -1035 -1035 179 -1035 -1035 -192 -1035 212 -1035 -192 167 -1035 -1035 -1035 -191 212 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GTGTGTGT MEME-4 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 13 E= 2.9e+003 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.153846 0.846154 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.076923 0.000000 0.923077 0.000000 0.076923 0.923077 0.000000 0.000000 0.000000 0.076923 0.923077 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GTGTGTGT MEME-4 regular expression -------------------------------------------------------------------------------- GTGTGTGT -------------------------------------------------------------------------------- Time 15.30 secs. ******************************************************************************** ******************************************************************************** MOTIF AAAATATA MEME-5 width = 8 sites = 2 llr = 25 E-value = 8.6e+003 ******************************************************************************** -------------------------------------------------------------------------------- Motif AAAATATA MEME-5 Description -------------------------------------------------------------------------------- Simplified A aaaa:a:a pos.-specific C :::::::: probability G :::::::: matrix T ::::a:a: bits 2.3 ******** 2.0 ******** 1.8 ******** 1.6 ******** Relative 1.4 ******** Entropy 1.1 ******** (18.1 bits) 0.9 ******** 0.7 ******** 0.5 ******** 0.2 ******** 0.0 -------- Multilevel AAAATATA consensus sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAAATATA MEME-5 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr7:159128355-159128435 50 3.57e-06 catgacaccg aaaatata acacacccca chr15:102520935-10252101 6 3.57e-06 taccc aaaatata acacccacgt -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAAATATA MEME-5 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr7:159128355-159128435 3.6e-06 49_[+5]_23 chr15:102520935-10252101 3.6e-06 5_[+5]_67 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAAATATA MEME-5 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF AAAATATA width=8 seqs=2 chr7:159128355-159128435 ( 50) AAAATATA 1 chr15:102520935-10252101 ( 6) AAAATATA 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAAATATA MEME-5 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 13.1555 E= 8.6e+003 227 -765 -765 -765 227 -765 -765 -765 227 -765 -765 -765 227 -765 -765 -765 -765 -765 -765 223 227 -765 -765 -765 -765 -765 -765 223 227 -765 -765 -765 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAAATATA MEME-5 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 2 E= 8.6e+003 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 1.000000 0.000000 0.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAAATATA MEME-5 regular expression -------------------------------------------------------------------------------- AAAATATA -------------------------------------------------------------------------------- Time 18.70 secs. ******************************************************************************** ******************************************************************************** SUMMARY OF MOTIFS ******************************************************************************** -------------------------------------------------------------------------------- Combined block diagrams: non-overlapping sites with p-value < 0.0001 -------------------------------------------------------------------------------- SEQUENCE NAME COMBINED P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr1:10049-10129 1.00e+00 80 chr2:243153822-243153902 5.70e-01 80 chr2:11607-11687 2.97e-01 80 chr18:11674-11754 9.95e-01 80 chr17:79093597-79093677 1.81e-03 48_[+1(2.38e-05)]_24 chr11:134945692-13494577 5.15e-01 80 chr2:19548149-19548229 9.82e-05 59_[+1(1.37e-05)]_13 chr6:139456066-139456146 1.13e-03 10_[+1(1.37e-05)]_29_[+1(1.37e-05)]_\ 25 chr19:17728312-17728392 1.11e-03 14_[+1(1.37e-05)]_58 chr14:68086437-68086517 2.00e-04 27_[+1(1.37e-05)]_45 chr19:50979516-50979596 6.59e-04 14_[+1(1.37e-05)]_19_[+1(1.37e-05)]_\ 31 chr4:119512822-119512902 9.61e-04 17_[+1(1.37e-05)]_17_[+1(1.37e-05)]_\ 30 chr1:249240178-249240258 1.00e+00 80 chr5:95297753-95297833 6.71e-04 30_[+1(1.37e-05)]_42 chr2:74781530-74781610 1.90e-03 9_[+1(2.38e-05)]_12_[+1(1.37e-05)]_\ 11_[+1(1.37e-05)]_24 chr11:77185401-77185481 1.22e-03 9_[+2(9.08e-05)]_28_[+1(1.37e-05)]_\ 27 chr15:102520935-10252101 5.98e-03 5_[+5(3.57e-06)]_67 chr19:50862181-50862261 1.38e-03 14_[+1(7.50e-05)]_28_[+1(1.37e-05)]_\ 3_[+2(7.21e-05)]_11 chr8:21967225-21967305 1.36e-03 50_[+1(1.37e-05)]_22 chr1:224180298-224180378 1.44e-03 47_[+1(1.37e-05)]_17_[+2(3.29e-05)] chr7:159128355-159128435 2.46e-04 49_[+5(3.57e-06)]_23 chr7:45808606-45808686 4.03e-04 48_[+1(1.37e-05)]_24 chr2:170696738-170696818 7.29e-01 80 chr21:43430342-43430422 9.58e-01 80 chr1:4052256-4052336 6.65e-03 2_[+1(2.38e-05)]_8_[+1(2.38e-05)]_6_\ [+1(2.38e-05)]_9_[+1(2.38e-05)]_9_[+1(2.38e-05)]_6 chr6:15248926-15249006 1.14e-03 48_[+1(1.37e-05)]_24 chr7:137686977-137687057 9.18e-05 26_[+1(1.37e-05)]_46 chr13:49821989-49822069 8.82e-04 10_[+1(1.37e-05)]_62 chr2:28114101-28114181 1.35e-03 25_[+2(3.29e-05)]_36_[+1(1.37e-05)]_\ 3 chr4:170541640-170541720 1.75e-03 32_[+1(1.37e-05)]_40 chr17:38136743-38136823 2.04e-03 17_[+1(1.37e-05)]_55 chr2:2577813-2577893 5.52e-03 16_[+1(2.38e-05)]_22_[+2(3.29e-05)]_\ 26 chr19:36103552-36103632 7.19e-04 54_[+1(1.37e-05)]_18 chr12:64616303-64616383 1.86e-04 62_[+1(1.37e-05)]_10 chr19:17462815-17462895 2.53e-03 16_[+4(2.88e-05)]_43_[+1(7.50e-05)]_\ 5 chr6:143381661-143381741 9.81e-01 80 chr9:33001613-33001693 1.17e-03 19_[+1(1.37e-05)]_23_[+1(1.37e-05)]_\ 22 chr18:10097-10177 1.00e+00 80 chr7:65235816-65235896 1.88e-03 34_[+1(1.37e-05)]_38 chr11:95523546-95523626 6.38e-05 20_[+1(1.37e-05)]_52 chr6:53213772-53213852 1.46e-03 16_[+1(1.37e-05)]_48_[+1(2.38e-05)] chr7:6413556-6413636 9.58e-01 80 chr8:146294970-146295050 4.32e-02 80 chr11:3818985-3819065 6.87e-04 52_[+1(1.37e-05)]_20 chr19:56015258-56015338 6.61e-04 23_[+1(1.37e-05)]_49 chr10:74397398-74397478 9.33e-04 34_[+3(8.11e-06)]_38 chr18:76829139-76829219 8.39e-04 [+1(1.37e-05)]_72 chr5:137673177-137673257 2.49e-03 17_[+1(2.38e-05)]_55 chr7:75795866-75795946 1.22e-03 70_[+1(1.37e-05)]_2 chr18:33647545-33647625 9.55e-01 80 chr6:44355167-44355247 1.31e-03 23_[+1(1.37e-05)]_49 chr10:70848851-70848931 7.36e-01 80 chr17:1196881-1196961 3.09e-03 57_[+1(2.38e-05)]_15 chr15:34807470-34807550 1.55e-01 63_[+4(1.44e-05)]_[+4(1.44e-05)]_1 chr16:89766723-89766803 1.92e-03 27_[+1(1.37e-05)]_45 chr5:11540-11620 9.98e-01 80 chr2:8144533-8144613 2.12e-04 50_[+1(1.37e-05)]_22 chr7:149469098-149469178 1.00e+00 80 chr17:76554590-76554670 4.57e-03 5_[+1(3.37e-05)]_14_[+1(3.37e-05)]_\ 14_[+1(3.37e-05)]_23 chr18:2655138-2655218 1.35e-03 16_[+1(1.37e-05)]_56 chr7:5492772-5492852 3.47e-04 52_[+1(1.37e-05)]_20 chr19:47616923-47617003 1.71e-03 39_[+3(3.37e-06)]_33 chr15:40401490-40401570 9.55e-01 80 chr9:100395594-100395674 1.39e-04 52_[+1(1.37e-05)]_20 chr16:3285179-3285259 7.86e-04 24_[+1(1.37e-05)]_48 chrX:135992426-135992506 9.98e-01 80 chr14:105219421-10521950 1.49e-03 50_[+1(1.37e-05)]_22 chr4:120375787-120375867 1.62e-03 47_[+1(1.37e-05)]_17_[+2(9.08e-05)] chr14:23388096-23388176 1.63e-03 12_[+2(9.08e-05)]_11_[+1(1.37e-05)]_\ 41 chr7:44646064-44646144 1.18e-03 35_[+1(1.37e-05)]_37 chr6:151362156-151362236 4.81e-01 80 chr7:140396442-140396522 1.13e-03 12_[+1(1.37e-05)]_60 chr19:49164457-49164537 9.90e-04 54_[+1(1.37e-05)]_18 chr12:31882013-31882093 8.57e-04 30_[+1(1.37e-05)]_42 chr8:125486895-125486975 8.23e-01 80 chr14:50053228-50053308 1.35e-03 18_[+1(1.37e-05)]_54 chr19:46009769-46009849 1.23e-03 60_[+1(1.37e-05)]_12 chr1:243265037-243265117 1.54e-03 [+2(3.29e-05)]_42_[+1(1.37e-05)]_22 chr22:38576158-38576238 1.27e-03 66_[+1(2.38e-05)]_6 chr14:55737961-55738041 8.57e-01 80 chr14:55738809-55738889 7.23e-06 30_[+4(4.33e-05)]_1_[+1(1.37e-05)]_\ 33 chr19:7571595-7571675 1.00e+00 80 chr7:65958507-65958587 1.85e-02 35_[+2(3.29e-05)]_37 chr7:39772934-39773014 1.44e-03 34_[+1(1.37e-05)]_38 chr20:30192128-30192208 1.08e-03 37_[+1(1.37e-05)]_35 chr19:51111407-51111487 9.38e-01 80 chr1:6320120-6320200 8.84e-04 45_[+1(1.37e-05)]_27 chr19:59092676-59092756 7.30e-01 80 chr12:10766173-10766253 1.46e-03 16_[+1(1.37e-05)]_56 chr17:7835466-7835546 7.15e-04 23_[+1(1.37e-05)]_49 chr7:30174232-30174312 1.78e-03 52_[+1(1.37e-05)]_20 chr6:148661-148741 8.52e-01 80 chr7:23571643-23571723 2.01e-04 24_[+1(1.37e-05)]_48 chr7:149388146-149388226 2.88e-01 80 chr16:85604599-85604679 2.86e-01 80 chr18:23806271-23806351 1.30e-03 34_[+1(1.37e-05)]_38 chr1:17004730-17004810 8.68e-02 22_[+3(3.24e-05)]_50 chr5:65020530-65020610 4.89e-01 80 chr12:133022743-13302282 5.71e-04 4_[+1(1.37e-05)]_43_[+1(1.37e-05)]_\ 17 chr19:59055494-59055574 4.73e-01 80 chr2:157192251-157192331 7.67e-01 80 chr1:2111911-2111991 3.43e-01 80 chr9:132539523-132539603 1.03e-03 21_[+1(1.37e-05)]_51 chr16:75657141-75657221 4.36e-04 48_[+1(1.37e-05)]_24 chr14:32030559-32030639 1.46e-03 21_[+1(1.37e-05)]_51 chr7:55433934-55434014 1.78e-03 62_[+1(1.37e-05)]_10 chr1:67944999-67945079 1.86e-01 80 chr17:40829281-40829361 1.16e-03 44_[+1(1.37e-05)]_28 chr7:140624852-140624932 7.84e-01 80 chr3:38206506-38206586 4.44e-04 23_[+1(1.37e-05)]_49 chr5:159436009-159436089 1.17e-03 21_[+1(1.37e-05)]_51 chr12:131249248-13124932 6.67e-03 43_[+1(2.38e-05)]_9_[+1(2.38e-05)]_\ 12 chr3:140660528-140660608 3.98e-06 12_[+3(6.38e-05)]_12_[+1(1.37e-05)]_\ 40 chr11:190104-190184 3.42e-01 80 chr19:36119873-36119953 2.90e-04 40_[+1(1.37e-05)]_32 chr8:144536788-144536868 9.76e-02 21_[+1(7.50e-05)]_51 chr6:28756797-28756877 1.47e-02 46_[+3(3.37e-06)]_[+3(8.11e-06)]_7_\ [+3(8.11e-06)]_3 chr7:99765621-99765701 5.76e-01 80 chr1:228296935-228297015 1.78e-01 80 chr12:123380768-12338084 9.66e-01 80 chr15:40401288-40401368 9.79e-01 80 chr7:44646264-44646344 8.00e-01 80 chr5:13292-13372 9.94e-01 80 chr11:4115967-4116047 3.74e-02 36_[+1(8.49e-05)]_36 chr12:120729911-12072999 6.83e-04 29_[+1(1.37e-05)]_43 chr22:21942495-21942575 8.83e-01 80 chr1:16872470-16872550 3.67e-02 61_[+3(1.94e-05)]_11 chr1:156698651-156698731 1.98e-02 50_[+1(7.50e-05)]_22 chr7:158990402-158990482 7.13e-01 80 chr11:85869980-85870060 1.31e-01 1_[+4(1.44e-05)]_2_[+4(1.44e-05)]_8_\ [+4(1.44e-05)]_[+4(1.44e-05)]_6_[+4(1.44e-05)]_[+4(1.44e-05)]_15 chr1:32110409-32110489 9.29e-04 64_[+1(1.37e-05)]_8 chr14:31699034-31699114 1.01e-02 80 chr9:125027101-125027181 1.76e-03 41_[+1(1.37e-05)]_31 chr7:129592772-129592852 8.06e-04 36_[+1(1.37e-05)]_6_[+1(1.37e-05)]_\ 22 chr1:9489019-9489099 5.23e-05 23_[+1(1.37e-05)]_49 chr16:57334190-57334270 9.53e-03 80 chr10:43876161-43876241 2.97e-02 8_[+3(4.57e-05)]_7_[+3(4.57e-05)]_2_\ [+3(8.11e-06)]_39 chr17:56744256-56744336 1.51e-03 23_[+1(1.37e-05)]_49 chr6:31939720-31939800 8.62e-04 20_[+1(1.37e-05)]_52 chr17:45784184-45784264 9.39e-01 80 chr10:81963156-81963236 9.88e-01 80 chr12:58138352-58138432 1.41e-04 37_[+3(4.57e-05)]_1_[+2(7.21e-05)]_\ 3_[+1(9.85e-05)]_15 chr2:127066156-127066236 5.88e-01 80 chr19:8454834-8454914 1.95e-03 23_[+1(1.37e-05)]_49 chr6:27125737-27125817 5.50e-02 80 chr1:714044-714124 1.54e-03 23_[+1(1.37e-05)]_17_[+1(1.37e-05)]_\ 24 chr5:78810426-78810506 2.72e-03 26_[+1(2.38e-05)]_46 chr9:111696365-111696445 4.32e-04 49_[+1(1.37e-05)]_23 chr16:67924458-67924538 1.93e-01 80 chr12:56521642-56521722 1.32e-04 46_[+1(1.37e-05)]_26 chr19:2962161-2962241 8.42e-05 37_[+1(1.37e-05)]_35 chr6:37400923-37401003 1.26e-03 49_[+1(1.37e-05)]_23 chr7:1546712-1546792 1.26e-01 66_[+4(2.88e-05)]_6 chr1:110527275-110527355 1.64e-03 21_[+1(1.37e-05)]_51 chr3:128598287-128598367 6.30e-04 17_[+1(1.37e-05)]_55 chr8:145682209-145682289 5.08e-03 2_[+1(3.37e-05)]_39_[+1(3.37e-05)]_\ 5_[+1(3.37e-05)]_10 chr19:51506089-51506169 4.14e-04 34_[+1(1.37e-05)]_38 chr10:75639463-75639543 8.64e-02 60_[+1(7.50e-05)]_12 chr3:9464514-9464594 3.78e-01 80 chr1:147737229-147737309 7.54e-02 80 chr19:9546217-9546297 4.01e-05 41_[+1(1.37e-05)]_31 chr6:3002421-3002501 2.70e-02 12_[+3(4.57e-05)]_60 chr1:4067797-4067877 1.09e-02 32_[+3(1.94e-05)]_40 chr6:3054188-3054268 8.19e-01 80 chr8:117768082-117768162 5.36e-04 18_[+1(1.37e-05)]_54 chr19:51014783-51014863 7.33e-04 3_[+2(7.21e-05)]_22_[+1(1.37e-05)]_\ 39 chr7:66309958-66310038 1.17e-03 16_[+1(1.37e-05)]_56 chr16:84627760-84627840 2.15e-01 80 chr7:124569881-124569961 1.44e-03 13_[+1(1.37e-05)]_59 chr15:42840942-42841022 1.58e-03 48_[+1(1.37e-05)]_24 chr19:49004992-49005072 1.00e+00 80 chr17:38689738-38689818 5.73e-02 58_[+4(1.44e-05)]_[+4(1.44e-05)]_6 chr7:6488065-6488145 1.15e-01 [+1(7.50e-05)]_72 chr1:1790231-1790311 8.11e-06 22_[+1(1.37e-05)]_36_[+3(2.29e-05)]_\ 6 chr1:40840265-40840345 5.47e-02 3_[+4(1.44e-05)]_[+4(1.44e-05)]_\ [+4(1.44e-05)]_53 chr5:159624897-159624977 1.73e-01 31_[+4(1.44e-05)]_[+4(1.44e-05)]_\ [+4(1.44e-05)]_[+4(1.44e-05)]_2_[+4(1.44e-05)]_7 chr6:30028915-30028995 1.83e-04 51_[+1(1.37e-05)]_21 chr19:55517486-55517566 1.70e-04 23_[+1(9.85e-05)]_29_[+1(1.37e-05)]_\ 12 chr3:58291936-58292016 1.51e-03 28_[+1(1.37e-05)]_44 chr7:100464925-100465005 3.05e-07 23_[+1(1.37e-05)]_39_[+3(3.37e-06)]_\ 2 chr18:77866838-77866918 1.15e-03 50_[+1(1.37e-05)]_22 chr1:203242454-203242534 1.35e-01 54_[+4(1.44e-05)]_18 chr1:204675712-204675792 1.17e-02 61_[+3(1.28e-05)]_11 chr1:27755019-27755099 5.23e-01 80 chr4:104119584-104119664 1.60e-03 22_[+1(1.37e-05)]_50 chr20:44420492-44420572 9.97e-01 80 chr6:2846434-2846514 7.70e-01 80 chr2:191184683-191184763 8.89e-01 80 chr11:809824-809904 1.66e-03 49_[+1(1.37e-05)]_23 chr19:46135924-46136004 1.55e-03 62_[+1(1.37e-05)]_10 chr7:158990188-158990268 5.86e-01 80 chr12:132628914-13262899 1.36e-04 37_[+2(3.29e-05)]_17_[+1(1.37e-05)]_\ 10 chr17:33914242-33914322 1.13e-03 12_[+1(1.37e-05)]_15_[+1(1.37e-05)]_\ 37 chr1:936243-936323 1.27e-03 10_[+1(1.37e-05)]_36_[+1(1.37e-05)]_\ 18 chr17:49010940-49011020 5.99e-03 31_[+3(3.37e-06)]_41 chr16:86588813-86588893 1.78e-03 27_[+1(1.37e-05)]_45 chr12:132344963-13234504 4.69e-02 12_[+3(1.28e-05)]_13_[+3(1.28e-05)]_\ 27_[+3(1.28e-05)]_4 chr11:3465439-3465519 7.11e-02 33_[+3(8.11e-06)]_19_[+3(1.94e-05)]_\ 12 chr17:26662482-26662562 8.82e-04 15_[+1(1.37e-05)]_57 chr12:110498140-11049822 2.42e-01 80 chr1:161500990-161501070 7.88e-02 80 chr6:31705872-31705952 8.79e-01 80 chr1:161067462-161067542 1.79e-01 65_[+4(1.44e-05)]_7 chr7:100271186-100271266 3.98e-01 80 chr7:23230811-23230891 6.15e-01 80 chr7:143599122-143599202 9.99e-01 80 chr5:64372397-64372477 9.87e-01 80 chr6:7119748-7119828 2.89e-03 15_[+3(1.28e-05)]_45_[+4(8.24e-05)]_\ 4 chr11:59315145-59315225 1.51e-01 80 chr7:23221562-23221642 5.80e-04 31_[+1(1.37e-05)]_41 chr1:168147948-168148028 8.84e-04 20_[+1(1.37e-05)]_52 chr16:68057124-68057204 3.99e-05 13_[+1(1.37e-05)]_47_[+4(8.24e-05)]_\ 4 chr4:80131394-80131474 8.85e-01 80 chr4:113558039-113558119 4.92e-04 16_[+1(1.37e-05)]_56 chr1:70820637-70820717 4.12e-04 13_[+3(9.21e-05)]_46_[+2(9.08e-05)]_\ 5 chr7:86781388-86781468 8.33e-01 80 chr3:99536615-99536695 2.52e-04 61_[+1(1.37e-05)]_11 chr8:54857713-54857793 9.22e-02 80 chr7:103560023-103560103 5.98e-02 80 chr6:138227402-138227482 2.52e-01 80 chr19:56825967-56826047 1.19e-03 41_[+1(1.37e-05)]_31 chr6:15622026-15622106 6.88e-01 80 chr1:202522920-202523000 4.64e-03 41_[+1(2.38e-05)]_31 chr11:111749988-11175006 1.29e-01 80 chr1:39456869-39456949 1.82e-04 40_[+1(1.37e-05)]_32 chr19:11646978-11647058 1.08e-03 15_[+1(1.37e-05)]_57 chr4:146019275-146019355 9.55e-01 80 chr1:249200547-249200627 7.69e-01 80 chr7:100076870-100076950 1.00e+00 80 chr2:105953796-105953876 2.88e-01 80 chr16:30887892-30887972 4.12e-01 80 chr11:75946659-75946739 4.83e-01 80 chr7:65564995-65565075 2.31e-01 80 chr1:247634573-247634653 7.63e-01 80 chr2:43823223-43823303 3.97e-04 54_[+1(1.37e-05)]_18 chr6:27640101-27640181 4.08e-01 80 chr19:40923028-40923108 8.11e-01 80 chr15:91537885-91537965 2.30e-04 49_[+1(1.37e-05)]_23 chr11:118481993-11848207 9.99e-01 80 chr2:68290122-68290202 1.09e-01 13_[+1(7.50e-05)]_59 chr1:1655800-1655880 1.70e-01 80 chr17:44178629-44178709 8.75e-01 80 chr4:57253606-57253686 1.13e-03 71_[+1(1.37e-05)]_1 chr6:43670450-43670530 4.92e-02 [+4(1.44e-05)]_2_[+4(1.44e-05)]_\ [+4(1.44e-05)]_[+4(1.44e-05)]_4_[+4(1.44e-05)]_34 chr22:19803147-19803227 7.34e-01 80 chr16:28874671-28874751 7.62e-01 80 chr10:81205870-81205950 6.69e-01 80 chr6:34664808-34664888 8.81e-01 80 chr1:31297143-31297223 9.22e-01 80 chr15:66130024-66130104 7.74e-01 80 -------------------------------------------------------------------------------- ******************************************************************************** ******************************************************************************** Stopped because requested number of motifs (5) found. ******************************************************************************** CPU: c17n09.farnam.hpc.yale.internal ********************************************************************************