******************************************************************************** MEME - Motif discovery tool ******************************************************************************** MEME version 5.3.3 (Release date: Sun Feb 7 15:39:52 2021 -0800) For further information on how to interpret these results please access https://meme-suite.org/meme. To get a copy of the MEME Suite software please access https://meme-suite.org. ******************************************************************************** ******************************************************************************** REFERENCE ******************************************************************************** If you use this program in your research, please cite: Timothy L. Bailey and Charles Elkan, "Fitting a mixture model by expectation maximization to discover motifs in biopolymers", Proceedings of the Second International Conference on Intelligent Systems for Molecular Biology, pp. 28-36, AAAI Press, Menlo Park, California, 1994. ******************************************************************************** ******************************************************************************** TRAINING SET ******************************************************************************** PRIMARY SEQUENCES= ../result/final_prediction/K562/fasta/RankLinear0.6_40/MNT.fasta CONTROL SEQUENCES= --none-- ALPHABET= ACGT Sequence name Weight Length Sequence name Weight Length ------------- ------ ------ ------------- ------ ------ chr19:30335300-30335380 1.0000 80 chr1:167191653-167191733 1.0000 80 chr12:4378612-4378692 1.0000 80 chr19:54666170-54666250 1.0000 80 chr4:90032286-90032366 1.0000 80 chr8:95907981-95908061 1.0000 80 chr9:140444862-140444942 1.0000 80 chrX:106920099-106920179 1.0000 80 chr11:66336092-66336172 1.0000 80 chr9:35116316-35116396 1.0000 80 chr12:48152906-48152986 1.0000 80 chr16:70148043-70148123 1.0000 80 chr21:47609219-47609299 1.0000 80 chr8:124553528-124553608 1.0000 80 chr22:41777511-41777591 1.0000 80 chr17:49336702-49336782 1.0000 80 chr19:50037104-50037184 1.0000 80 chr2:11919416-11919496 1.0000 80 chr19:55691518-55691598 1.0000 80 chr11:45868783-45868863 1.0000 80 chr17:2303037-2303117 1.0000 80 chr4:186317807-186317887 1.0000 80 chr16:14728077-14728157 1.0000 80 chr15:68522409-68522489 1.0000 80 chr16:74402183-74402263 1.0000 80 chr15:85524117-85524197 1.0000 80 chr8:144025193-144025273 1.0000 80 chr12:56513308-56513388 1.0000 80 chr11:9594378-9594458 1.0000 80 chr9:132020876-132020956 1.0000 80 chr17:7184770-7184850 1.0000 80 chr5:175963612-175963692 1.0000 80 chr16:56966970-56967050 1.0000 80 chr10:103893360-10389344 1.0000 80 chr10:104474508-10447458 1.0000 80 chr10:104677816-10467789 1.0000 80 chr2:239197523-239197603 1.0000 80 chr19:55768869-55768949 1.0000 80 chr17:7747483-7747563 1.0000 80 chr16:4784752-4784832 1.0000 80 chr17:37558909-37558989 1.0000 80 chr12:120763357-12076343 1.0000 80 chr18:23807913-23807993 1.0000 80 chr3:49966997-49967077 1.0000 80 chr7:155090786-155090866 1.0000 80 chr2:30369408-30369488 1.0000 80 chr19:18547744-18547824 1.0000 80 chr19:14115774-14115854 1.0000 80 chr15:85143708-85143788 1.0000 80 chr1:156251164-156251244 1.0000 80 chr19:46270851-46270931 1.0000 80 chr20:39657118-39657198 1.0000 80 chr3:66271349-66271429 1.0000 80 chr8:81397755-81397835 1.0000 80 chr12:107487495-10748757 1.0000 80 chr17:42404342-42404422 1.0000 80 chr21:33765248-33765328 1.0000 80 chr15:41407817-41407897 1.0000 80 chr1:24120008-24120088 1.0000 80 chr12:26267443-26267523 1.0000 80 chr17:5323318-5323398 1.0000 80 chr17:44269101-44269181 1.0000 80 chr3:183353354-183353434 1.0000 80 chr16:30418599-30418679 1.0000 80 chr17:2303883-2303963 1.0000 80 chr19:1864267-1864347 1.0000 80 chr1:6661285-6661365 1.0000 80 chr4:57302508-57302588 1.0000 80 chr6:11112062-11112142 1.0000 80 chr5:139927199-139927279 1.0000 80 chr19:17580250-17580330 1.0000 80 chr3:167814046-167814126 1.0000 80 chr16:3202254-3202334 1.0000 80 chr17:75316972-75317052 1.0000 80 chr3:67048544-67048624 1.0000 80 chr10:104001484-10400156 1.0000 80 chr3:186648864-186648944 1.0000 80 chr12:122461414-12246149 1.0000 80 chr17:25853698-25853778 1.0000 80 chr16:31045663-31045743 1.0000 80 chr17:4268536-4268616 1.0000 80 chr19:18452167-18452247 1.0000 80 chr4:52710951-52711031 1.0000 80 chr17:2305017-2305097 1.0000 80 chr2:232328534-232328614 1.0000 80 chr4:87952118-87952198 1.0000 80 chr11:3663824-3663904 1.0000 80 chr2:75062121-75062201 1.0000 80 chr12:53765220-53765300 1.0000 80 chr10:11916876-11916956 1.0000 80 chr9:127963007-127963087 1.0000 80 chr16:29605738-29605818 1.0000 80 chr19:49655096-49655176 1.0000 80 chr19:1847775-1847855 1.0000 80 chr19:30433691-30433771 1.0000 80 chr20:30467594-30467674 1.0000 80 chr12:132380705-13238078 1.0000 80 chr19:47733585-47733665 1.0000 80 chr8:145800926-145801006 1.0000 80 chr17:66453941-66454021 1.0000 80 chr19:1672499-1672579 1.0000 80 chr6:42016722-42016802 1.0000 80 chr11:120894731-12089481 1.0000 80 chr19:45909116-45909196 1.0000 80 chr1:42800131-42800211 1.0000 80 chr12:110151420-11015150 1.0000 80 chr16:88519030-88519110 1.0000 80 chr2:85766880-85766960 1.0000 80 chr11:94226537-94226617 1.0000 80 chr9:140429452-140429532 1.0000 80 chr12:109535789-10953586 1.0000 80 chr3:38495175-38495255 1.0000 80 chr9:6007106-6007186 1.0000 80 chr2:113403223-113403303 1.0000 80 chr1:12203863-12203943 1.0000 80 chr1:110162327-110162407 1.0000 80 chr17:8055855-8055935 1.0000 80 chr19:18350288-18350368 1.0000 80 chr10:99094492-99094572 1.0000 80 chr20:44992642-44992722 1.0000 80 chr4:2264036-2264116 1.0000 80 chr17:34890805-34890885 1.0000 80 chr17:33307430-33307510 1.0000 80 chr11:65624483-65624563 1.0000 80 chr20:305106-305186 1.0000 80 chr2:191746736-191746816 1.0000 80 chr5:176739254-176739334 1.0000 80 chr11:118851021-11885110 1.0000 80 chr10:120924970-12092505 1.0000 80 chr12:104354526-10435460 1.0000 80 chr7:65580511-65580591 1.0000 80 chr6:5261357-5261437 1.0000 80 chr17:71088795-71088875 1.0000 80 chr17:36831359-36831439 1.0000 80 chr4:109087760-109087840 1.0000 80 chr1:44445511-44445591 1.0000 80 chr11:77531990-77532070 1.0000 80 chr11:12131916-12131996 1.0000 80 chr7:100450152-100450232 1.0000 80 chr16:22960172-22960252 1.0000 80 chr1:25758746-25758826 1.0000 80 chr17:4635124-4635204 1.0000 80 chr10:102747302-10274738 1.0000 80 chr3:122512698-122512778 1.0000 80 chr8:99129449-99129529 1.0000 80 chr16:27246710-27246790 1.0000 80 chr19:2977363-2977443 1.0000 80 chr8:26240466-26240546 1.0000 80 chr19:2346177-2346257 1.0000 80 chr1:155243341-155243421 1.0000 80 chr19:2151825-2151905 1.0000 80 chr19:1045089-1045169 1.0000 80 chr16:83986630-83986710 1.0000 80 chr22:31686769-31686849 1.0000 80 chr11:107729295-10772937 1.0000 80 chr12:62654825-62654905 1.0000 80 chr4:57301611-57301691 1.0000 80 chr8:109455753-109455833 1.0000 80 chr11:537305-537385 1.0000 80 chr16:58549328-58549408 1.0000 80 chr16:75267965-75268045 1.0000 80 chr17:38269599-38269679 1.0000 80 chr5:154062178-154062258 1.0000 80 chr17:38255627-38255707 1.0000 80 chr10:99161011-99161091 1.0000 80 chr9:73029013-73029093 1.0000 80 chr17:17109832-17109912 1.0000 80 chr4:89514398-89514478 1.0000 80 chr16:89283045-89283125 1.0000 80 chr11:119252508-11925258 1.0000 80 chr12:50813523-50813603 1.0000 80 chr3:183967325-183967405 1.0000 80 chr12:123848118-12384819 1.0000 80 chr16:89766698-89766778 1.0000 80 chr12:113659616-11365969 1.0000 80 chr20:42839576-42839656 1.0000 80 chr11:123940245-12394032 1.0000 80 chr4:110736922-110737002 1.0000 80 chr9:140563962-140564042 1.0000 80 chr1:211752937-211753017 1.0000 80 chr17:53315698-53315778 1.0000 80 chr19:5341040-5341120 1.0000 80 chr17:58754771-58754851 1.0000 80 chr1:33501781-33501861 1.0000 80 chr3:12909893-12909973 1.0000 80 chr12:49463690-49463770 1.0000 80 chr16:88877868-88877948 1.0000 80 chr19:41903292-41903372 1.0000 80 chr10:75911098-75911178 1.0000 80 chr19:4327290-4327370 1.0000 80 chr2:68385006-68385086 1.0000 80 chr22:39541778-39541858 1.0000 80 chr5:78642360-78642440 1.0000 80 chr17:4458609-4458689 1.0000 80 chr5:90628226-90628306 1.0000 80 chr19:13096198-13096278 1.0000 80 chr19:10400007-10400087 1.0000 80 chr8:11660056-11660136 1.0000 80 chr3:69788420-69788500 1.0000 80 chr1:31654643-31654723 1.0000 80 chr6:109704113-109704193 1.0000 80 chr12:120755569-12075564 1.0000 80 chr19:7570833-7570913 1.0000 80 chr7:30323892-30323972 1.0000 80 chr22:24181346-24181426 1.0000 80 chr16:79867620-79867700 1.0000 80 chrX:129216521-129216601 1.0000 80 chr4:17579035-17579115 1.0000 80 chr12:131324045-13132412 1.0000 80 chr5:170815538-170815618 1.0000 80 chr16:128043-128123 1.0000 80 chr12:104682569-10468264 1.0000 80 chr4:83351705-83351785 1.0000 80 chr15:75497201-75497281 1.0000 80 chr22:41763217-41763297 1.0000 80 chr3:50563567-50563647 1.0000 80 chr14:77279230-77279310 1.0000 80 chr9:140565420-140565500 1.0000 80 chrX:153991776-153991856 1.0000 80 chr12:8380264-8380344 1.0000 80 chr10:50747182-50747262 1.0000 80 chr19:4968834-4968914 1.0000 80 chr2:88991322-88991402 1.0000 80 chr5:175815548-175815628 1.0000 80 chr10:26986846-26986926 1.0000 80 chr1:6454167-6454247 1.0000 80 chr16:69166527-69166607 1.0000 80 chr5:137690800-137690880 1.0000 80 chr15:98503705-98503785 1.0000 80 chr19:50180739-50180819 1.0000 80 chr22:29949800-29949880 1.0000 80 chr4:103266662-103266742 1.0000 80 chr11:114310015-11431009 1.0000 80 chr6:97345678-97345758 1.0000 80 chr4:4291771-4291851 1.0000 80 chr21:46961665-46961745 1.0000 80 chr20:20033178-20033258 1.0000 80 chr8:103425154-103425234 1.0000 80 chr1:159750735-159750815 1.0000 80 chr11:71159706-71159786 1.0000 80 chr7:77485128-77485208 1.0000 80 chr5:172410732-172410812 1.0000 80 chr19:36605861-36605941 1.0000 80 chr1:227128125-227128205 1.0000 80 chr1:3541337-3541417 1.0000 80 chr1:31628299-31628379 1.0000 80 chr1:44457189-44457269 1.0000 80 chr2:157189160-157189240 1.0000 80 chr22:40742713-40742793 1.0000 80 chr3:182817397-182817477 1.0000 80 ******************************************************************************** ******************************************************************************** COMMAND LINE SUMMARY ******************************************************************************** This information can also be useful in the event you wish to report a problem with the MEME software. command: meme -oc ../result/final_prediction/K562/inference_raw/MEME/RankLinear0.6_40_MNT/ -dna -nmotifs 5 -w 8 -maxsize 250000 -nostatus ../result/final_prediction/K562/fasta/RankLinear0.6_40/MNT.fasta model: mod= zoops nmotifs= 5 evt= inf objective function: em= E-value of product of p-values starts= E-value of product of p-values strands: + width: minw= 8 maxw= 8 nsites: minsites= 2 maxsites= 250 wnsites= 0.8 theta: spmap= uni spfuzz= 0.5 em: prior= dirichlet b= 0.01 maxiter= 50 distance= 1e-05 trim: wg= 11 ws= 1 endgaps= yes data: n= 20000 N= 250 sample: seed= 0 hsfrac= 0 searchsize= 20000 norand= no csites= 1000 Letter frequencies in dataset: A 0.181 C 0.319 G 0.319 T 0.181 Background letter frequencies (from file dataset with add-one prior applied): A 0.181 C 0.319 G 0.319 T 0.182 Background model order: 0 ******************************************************************************** ******************************************************************************** MOTIF CCACGTGS MEME-1 width = 8 sites = 213 llr = 1625 E-value = 1.2e-238 ******************************************************************************** -------------------------------------------------------------------------------- Motif CCACGTGS MEME-1 Description -------------------------------------------------------------------------------- Simplified A 1:a:1::: pos.-specific C 6a:9:::3 probability G 3:::9:a5 matrix T :::1:a:1 bits 2.5 2.2 * * 2.0 * * 1.7 ** ** Relative 1.5 ****** Entropy 1.2 ****** (11.0 bits) 1.0 ****** 0.7 ****** 0.5 ****** 0.2 ******** 0.0 -------- Multilevel CCACGTGG consensus G C sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCACGTGS MEME-1 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr1:31628299-31628379 47 3.47e-05 GGCGCCGGGG CCACGTGG AGTCTGCGCG chr7:77485128-77485208 25 3.47e-05 tctgtccaca ccacgtgg ctgctgctgg chr11:71159706-71159786 15 3.47e-05 GGCGGAGTGG CCACGTGG GCCGCGCGGA chr1:159750735-159750815 20 3.47e-05 GCCCTGCAGA CCACGTGG CCCGGGAGGC chr19:50180739-50180819 59 3.47e-05 ATCCCCCCTC CCACGTGG AGGAGGGCTG chr10:50747182-50747262 28 3.47e-05 ACGGGCAAGA CCACGTGG TTTGGAGGGA chr12:8380264-8380344 12 3.47e-05 GGGCCTGGGG CCACGTGG CACGGAGAGA chrX:153991776-153991856 24 3.47e-05 TCTGCCATAG CCACGTGG TGAACCGGAA chr14:77279230-77279310 26 3.47e-05 ccggtccggc ccACGTGG TGCCGCCGCC chr4:83351705-83351785 31 3.47e-05 CTTTTCCTGC CCACGTGG TCTCGGGCTC chr5:170815538-170815618 50 3.47e-05 CACGTGGTTG CCACGTGG TTGGGGGAGG chr12:120755569-12075564 53 3.47e-05 GTAAATAAGG CCACGTGG CTTTTTCTCC chr19:13096198-13096278 45 3.47e-05 CTCCGTGTGG CCACGTGG CTAGCACAGC chr5:90628226-90628306 38 3.47e-05 tcagttaagg ccacgtgg tcagtgctaa chr10:75911098-75911178 59 3.47e-05 AAGCCAGGGC CCACGTGG GGTTGCACGG chr1:211752937-211753017 30 3.47e-05 CGAGCCCAGT CCACGTgg gggcgggccg chr12:50813523-50813603 22 3.47e-05 aacaacctat ccacgtgg tggctcaaac chr11:119252508-11925258 24 3.47e-05 ACACAGAGAA CCACGTGG AGGAAAAGCA chr10:99161011-99161091 48 3.47e-05 CGCTCAGAAC CCACGTGG ATACCCTGTA chr17:38269599-38269679 67 3.47e-05 GAAGGGAGGT CCACGTGG AGTGGG chr16:58549328-58549408 26 3.47e-05 AAAACAGGCA CCACGTGG TTCCGGCGCC chr11:537305-537385 61 3.47e-05 ACGTGCCAGT CCACGTGG CCCCGCCCTA chr12:62654825-62654905 68 3.47e-05 TTATGAGAGA CCACGTGG TCTTG chr19:2151825-2151905 65 3.47e-05 GGCGGGGCGC CCACGTGG AGCTTAGC chr19:2346177-2346257 54 3.47e-05 ACCCTGCCCT CCACGTGG CTCCCTAAAC chr16:27246710-27246790 61 3.47e-05 AACGCCAATG CCACGTGG CTTCTTTCTT chr8:99129449-99129529 43 3.47e-05 ACGCTCCAGG CCACGTGG AGGAAGCGCC chr16:22960172-22960252 41 3.47e-05 GGATCATGCG CCACGTGG CTTAACAGCA chr7:65580511-65580591 68 3.47e-05 CAGTTTAACT CCACGTGG TCTTT chr11:118851021-11885110 5 3.47e-05 CGCA CCACGTGG ATGCTTTGCC chr17:33307430-33307510 28 3.47e-05 CAACTACGAC CCACGTGG CAGACGGGGG chr1:110162327-110162407 54 3.47e-05 TGGTGGCTGC CCACGTGG CGCCCAGGAA chr9:140429452-140429532 48 3.47e-05 gcaagagaga ccacgtgg cccataaagc chr17:66453941-66454021 46 3.47e-05 GGCAGCAGGC CCACGTGG CGGTGTTTTC chr16:29605738-29605818 13 3.47e-05 TTCAATATTA CCACGTGG GGGTCACAGA chr9:127963007-127963087 57 3.47e-05 CCTAGAACTG CCACGTGG GGATGAGATT chr10:11916876-11916956 43 3.47e-05 GAACCCAGCT CCACGTGG CCTACCTCCC chr19:18452167-18452247 52 3.47e-05 CGCCTCGGGG CCACGTGG GGCGCCAACT chr10:104001484-10400156 20 3.47e-05 GCGCCCCTCC CCACGTGG CAGAGACCGC chr17:5323318-5323398 69 3.47e-05 AAATCTGTCT CCACGTGG GGCC chr1:24120008-24120088 37 3.47e-05 GCCTCCAGCC CCACGTGG CAGGTTGCCT chr20:39657118-39657198 24 3.47e-05 TAAAGGCCCA CCACGTGG CTGCGCGGCC chr3:49966997-49967077 20 3.47e-05 TGCCTCCAGG CCACGTGG GCTGGCAGTC chr10:104474508-10447458 61 3.47e-05 CCTGCAGAAG CCACGTGG CGCGAAGTGC chr10:103893360-10389344 40 3.47e-05 GCCCGGGCAT CCACGTGG GTCGGGCTCC chr16:74402183-74402263 41 3.47e-05 CCCGCCCCTG CCACGTGG GCTTGTTTGG chr2:11919416-11919496 33 3.47e-05 GGCGGGCGAC CCACGTGG AGCGCCTTCC chr8:124553528-124553608 19 3.47e-05 GGCCCGGAGG CCACGTGG CTTTGTTTAT chr21:47609219-47609299 21 3.47e-05 TGCTGCTACC CCACGTGG GGGAGAACAC chr16:70148043-70148123 32 3.47e-05 CCAAACAAGC CCACGTGG CAGGGGCGGG chr12:48152906-48152986 47 3.47e-05 GCACTGGCCG CCACGTGG CCGGGAGGAG chr3:182817397-182817477 48 6.94e-05 GGCAGTCTGG CCACGTGC TCGTGGGGGT chr2:88991322-88991402 11 6.94e-05 TCCCGGGTTC CCACGTGC GGCTGCCGGG chr22:41763217-41763297 46 6.94e-05 CGCGACAGCT CCACGTGC TGCAGCTGGC chr4:17579035-17579115 10 6.94e-05 CACCGCTCT CCACGTGC TCGCTGGAGG chrX:129216521-129216601 22 6.94e-05 TCCTCTCGCC CCACGTGC CCTCAGCGCT chr7:30323892-30323972 36 6.94e-05 CGTCGGCGGG CCACGTGC GGGAGGAGGG chr19:7570833-7570913 46 6.94e-05 CACCCAGCCG CCACGTGC CTCATGAGAA chr16:88877868-88877948 26 6.94e-05 CGCGCAGAGC CCACGTGC TGCCCTCGGC chr17:58754771-58754851 11 6.94e-05 GCTGCCATGT CCACGTGC TCCGAGCTTG chr16:89766698-89766778 41 6.94e-05 CGTAGCTCGC CCACGTGC CCAGTGACGT chr17:17109832-17109912 65 6.94e-05 ccaccaACGG CCACGTGC AAGGTCAC chr11:107729295-10772937 20 6.94e-05 TGCTCCTTGT CCACGTGC GCGCAGGGCC chr1:155243341-155243421 20 6.94e-05 GCGCGCGCCA CCACGTGC TCACGTAGTT chr19:2977363-2977443 58 6.94e-05 GAGCCCGAAC CCACGTGC AGCTACTGCG chr19:18350288-18350368 43 6.94e-05 acaatgggac ccacgtgc gccagacaca chr1:12203863-12203943 39 6.94e-05 CATCGGGCAG CCACGTGC TCTCTGGAGG chr19:45909116-45909196 26 6.94e-05 AAATCTGTGT CCACGTGC CGCTGTTTAC chr6:42016722-42016802 5 6.94e-05 TCCT CCACGTGC TATCCAGGAA chr19:1672499-1672579 23 6.94e-05 CGGGCGCTCC CCACGTGC GCGCTCACAC chr19:49655096-49655176 23 6.94e-05 AGGCCCCGGC CCACGTGC TCAGAGCCTT chr11:3663824-3663904 15 6.94e-05 ACACCCTGGG CCACGTGC TCCAGCATCT chr4:87952118-87952198 32 6.94e-05 TGACAGTTTT CCACGTGC ACAGTAATTT chr12:122461414-12246149 22 6.94e-05 TCAATAAAGT CCACGTGC TCCCCGGCCT chr3:186648864-186648944 19 6.94e-05 CACAACAAAC CCACGTGC GCACAGCCCC chr4:57302508-57302588 48 6.94e-05 GAGCTCGCGG CCACGTGC GAGCCGCGAA chr17:2303883-2303963 50 6.94e-05 CGGCCGCTCA CCACGTGC TCTCTGTTGT chr15:41407817-41407897 49 6.94e-05 CCACCGGGTC CCACGTGC ACCTGGTCTA chr11:9594378-9594458 17 6.94e-05 CAACGCATGC CCACGTGC TGGCGAACAA chr8:144025193-144025273 54 6.94e-05 CCTGTAATGC CCACGTGC ATGTCCATTC chr4:186317807-186317887 25 6.94e-05 gcgccgggcT CCACGTGC CAGTGTTTGT chr17:49336702-49336782 28 6.94e-05 ATTTCCACCT CCACGTGC AAACCGCCTC chr9:35116316-35116396 56 6.94e-05 CCCACCCCGG CCACGTGC GGCTTCTGTG chr4:90032286-90032366 17 6.94e-05 TAAACACGCC CCACGTGC GCTCGCCCTG chr19:30335300-30335380 58 6.94e-05 AGGCTGCGCT CCACGTGC GCCGTGTTTA chr4:4291771-4291851 35 1.24e-04 GCCGCGGGGA GCACGTGG ACTCGCCGCC chr6:97345678-97345758 33 1.24e-04 GGTTCAGGCC GCACGTGG GAACACCGGC chr4:103266662-103266742 39 1.24e-04 CGCCTCCGTA GCACGTGG TGACCCATTT chr16:69166527-69166607 8 1.24e-04 CGCGCGC GCACGTGG GGCCGGGGCG chr19:4968834-4968914 48 1.24e-04 CGGTCAGCGG GCACGTGG GTGGGCGCCG chr9:140565420-140565500 48 1.24e-04 AAGCCGCTGT GCACGTGG TTGAATGTAA chr22:24181346-24181426 50 1.24e-04 CCAAGGTTGA GCACGTGG CGGTTGTTGT chr1:31654643-31654723 60 1.24e-04 GGGCCGTGAC CCACGTGT ACAGAGGCTG chr19:41903292-41903372 55 1.24e-04 CTGGGCGTCC GCACGTGG CTTAGCGTTT chr1:33501781-33501861 69 1.24e-04 TCACTCTGCC CCACGTGT TGGA chr4:110736922-110737002 26 1.24e-04 GGCCAGAGGG GCACGTGG CGCCGGTGAG chr12:113659616-11365969 66 1.24e-04 GGGGCTGGGA GCACGTGG AGCTGGA chr3:183967325-183967405 37 1.24e-04 GACGGAAGTT CCACGTGT TTGTGTTGAG chr17:38255627-38255707 64 1.24e-04 AACAAACGCA GCACGTGG GCCCGGCTC chr5:154062178-154062258 4 1.24e-04 GAA CCACGTGT ACCCACGGGA chr4:57301611-57301691 46 1.24e-04 GCCGCCGAAA GCACGTGG AAGGACCTGC chr7:100450152-100450232 65 1.24e-04 ATCCCCGGGC GCACGTGG AGCTGGAG chr1:44445511-44445591 34 1.24e-04 TCCGCGGGTG CCACGTGT TCAGCCTGCC chr4:109087760-109087840 22 1.24e-04 TAGCCAGCAC CCACGTGT CTCTATTTAC chr17:36831359-36831439 73 1.24e-04 ATGCGCCGCC GCACGTGG chr5:176739254-176739334 22 1.24e-04 CCCAGCCGCT GCACGTGG GTgccgcggg chr17:34890805-34890885 27 1.24e-04 CGCGGGGCGC GCACGTGG CTTGGCCGGG chr4:2264036-2264116 32 1.24e-04 CTTAGCAACA GCACGTGG TGGCCCGGCC chr17:8055855-8055935 34 1.24e-04 ACACACGGGC GCACGTGG ACCTGGGTGC chr2:85766880-85766960 50 1.24e-04 GCAGCGGCGA CCACGTGT TTGCCGCATG chr16:88519030-88519110 59 1.24e-04 CCCCCACCGC GCACGTGG AGCGTGCGGC chr2:75062121-75062201 26 1.24e-04 TCCGGCGAGA GCACGTGG AGAGAATCGT chr2:232328534-232328614 28 1.24e-04 CCGGGGCCCA CCACGTGT CGGCTTGCCA chr4:52710951-52711031 37 1.24e-04 TGGGTTGGGT GCACGTGG GTAACTGTGG chr17:4268536-4268616 39 1.24e-04 AAATCTGGCA GCACGTGG GGCTGCATTG chr3:167814046-167814126 43 1.24e-04 CGTTCGGAAC GCACGTGG AGAGCGGAGT chr5:139927199-139927279 34 1.24e-04 GCCAGCAGCT GCACGTGG TCGGCTGAGT chr16:30418599-30418679 7 1.24e-04 GGGAGC GCACGTGG CCTATTTCGG chr17:42404342-42404422 27 1.24e-04 TGCCGGGTTA GCACGTGG ACTCCGAGGG chr15:85524117-85524197 56 1.24e-04 GCGAGGGAGC GCACGTGG GCTGCGGCTT chr15:68522409-68522489 53 1.24e-04 GCGTGGTGCA GCACGTGG GTTGCAGATG chr19:55691518-55691598 37 1.24e-04 CCCACCCCCT GCACGTGG GCGGTGGCGC chr11:66336092-66336172 30 1.24e-04 TTTACAGGAG GCACGTGG GGCGCGCAGG chr11:114310015-11431009 9 1.44e-04 CCAGAAAA ACACGTGG CGGGGGTGGG chr3:50563567-50563647 34 1.44e-04 GACTCAGCAG ACACGTGG CTGGGCTCAG chr19:5341040-5341120 17 1.44e-04 GCTTCGCGGG ACACGTGg gcggctgggg chr16:75267965-75268045 22 1.44e-04 acacactagc acacgtgg acacacacac chr3:122512698-122512778 53 1.44e-04 GGAAATACAA ACACGTGG TCTGAGTTGT chr17:4635124-4635204 32 1.44e-04 CTTCAGTGCA ACACGTGG AGGCGGAGCT chr17:71088795-71088875 53 1.44e-04 TCCCTCCCGC ACACGTGG CCCTCCCGCC chr20:305106-305186 28 1.44e-04 GAACTGGCTC ACACGTGG TGAGCCGGGA chr11:94226537-94226617 17 1.44e-04 AAATAAACAA ACACGTGG TCTGCGGAGG chr8:145800926-145801006 46 1.44e-04 agaaagcaac acacgtgg agccatcacc chr12:120763357-12076343 29 1.44e-04 CTAGAAAATG ACACGTGG ATAGTTGCTG chr17:7184770-7184850 5 1.44e-04 CCTA ACACGTGG GTGGGCGGGG chr12:56513308-56513388 51 1.44e-04 GGGAGGTCAG ACACGTGG TAGCAGGGAC chr22:40742713-40742793 54 1.78e-04 GCCCGCCCCA GCACGTGC CGGGCTCTGT chr15:98503705-98503785 17 1.78e-04 AACGGCCTGT GCACGTGC ACGCCGGAGC chr10:26986846-26986926 8 1.78e-04 GCGGGGA GCACGTGC GTCGCGACGC chr17:53315698-53315778 50 1.78e-04 GCAGGACCAG GCACGTGC GATTCCACGT chr9:140563962-140564042 44 1.78e-04 GCCCCGCACA GCACgtgc actcaccgac chr20:42839576-42839656 31 1.78e-04 CCCCTCAGAA GCACGTGC GCCTTACGTA chr3:66271349-66271429 27 1.78e-04 GTCTCGCGTT GCACGTGC AGTTGTTGTG chr19:55768869-55768949 55 1.78e-04 tgacatatct gcacgtgc tgctccttcc chr16:14728077-14728157 23 1.78e-04 GGCAGGGACT GCACGTGC TGATGGGGTT chr19:50037104-50037184 25 1.78e-04 GAGAGGTGCA GCACGTGC AGGCCGAGGG chr19:36605861-36605941 10 2.18e-04 GAGCTGCGC ACACGTGC TGGCTCCCCG chr8:103425154-103425234 36 2.18e-04 GTTCCGGAGA GCACGTGT TAGGGAAGGA chr21:46961665-46961745 57 2.18e-04 TCCCGAAGCA ACACGTGC CTGGGCGCGA chr1:6454167-6454247 32 2.18e-04 GCCTGGAGGT GCACGTGT TGCAGTGAGG chr5:78642360-78642440 68 2.18e-04 CGTGGCAAAT GCACGTGT GCGGA chr2:68385006-68385086 22 2.18e-04 GTGCAGCTGC GCACGTGT TTCAGCCGGC chr2:191746736-191746816 29 2.18e-04 GCTACCTCAG GCACGTGT AGAGCCATCT chr9:6007106-6007186 28 2.18e-04 CCATCCTCGG GCACGTGT GAGTGTGTGT chr11:120894731-12089481 36 2.18e-04 AGCGGACGTG ACACGTGC GGCGGGGTCA chr8:81397755-81397835 25 2.18e-04 cccagtgaac gcacgtgt tcgacctttt chr1:156251164-156251244 41 2.18e-04 ATGATAAGGC ACACGTGC CACCCCCAGC chr18:23807913-23807993 33 2.18e-04 CTGACTGGGA ACACGTGC CACAGTTGAC chr19:10400007-10400087 51 2.29e-04 GCGCGCACGC ACACGTGT CCTCGGCTCG chr17:4458609-4458689 37 2.29e-04 GAAACACGAA ACACGTGT GCTCCGGCCC chr12:123848118-12384819 25 2.29e-04 CCTTCCCTCA ACACGTGT TCAGTACAAA chr16:3202254-3202334 40 2.29e-04 GGAAAATAAC ACACGTGT TGGGGCAGGA chr19:17580250-17580330 62 2.29e-04 AGGCTGCAGG ACACGTGT GTTTCCTAAA chr9:132020876-132020956 11 2.29e-04 GGGCTCCCAG ACACGTGT CCCCGGGAGC chr5:172410732-172410812 14 2.49e-04 GGCGCGCGGG TCACGTGG GGGCGCGGGA chr8:26240466-26240546 33 2.49e-04 TGTGTTGTCA TCACGTGG CCTGGGCGGG chr2:30369408-30369488 24 2.49e-04 AGAAGCTGAC TCACGTGG ATGCTGTGTT chr9:140444862-140444942 28 2.49e-04 TAAACAGCCC TCACGTGG CTGTCCCGGA chr16:79867620-79867700 6 2.88e-04 CTTAT CCACATGG TCAGGATGTT chr22:39541778-39541858 5 2.88e-04 ACGG CCACGTGA CCTCCCCGCC chr12:49463690-49463770 44 2.88e-04 CCGGAGCTGC CCACGTGA TCACAACACA chr11:65624483-65624563 16 2.88e-04 AAGAAGCCGG CCACGTGA CTCGGCCGCA chr17:2305017-2305097 23 2.88e-04 TGGAGCAGCT CCACATGG ACACCCCGCG chr17:44269101-44269181 47 2.88e-04 TGATTGCTAG CCACGTGA CAAAGGAGAT chr21:33765248-33765328 61 2.88e-04 CGCTTCAGGC CCACATgg cgcaggaaga chr16:56966970-56967050 45 2.88e-04 GCCCTGGCCA CCACGTGA TGAGGCTGTA chr19:30433691-30433771 10 3.28e-04 AAACTTTTG TCACGTGC TTCTGTTGTC chr20:44992642-44992722 33 3.39e-04 CCTTGTTTGC TCACGTGT TTACTGCCCG chr17:25853698-25853778 55 3.39e-04 AGAGGTCCTC TCACGTGT TGGAAAACGT chrX:106920099-106920179 27 3.59e-04 GCATGGAGGC CCACATGC CTTACGCTCC chr15:75497201-75497281 1 4.29e-04 . CCATGTGC CTAGGAATCG chr19:1847775-1847855 33 4.29e-04 GCGGCCACAA GCACATGG GGTCCGGGAA chr6:11112062-11112142 25 4.29e-04 ttgggaggag ccacatgt gcatttgttt chr2:239197523-239197603 60 4.29e-04 TACATAAGAC GCACATGG AACTCCATGT chr5:175963612-175963692 32 4.29e-04 GGATCCCGGA CCATGTGC TCGGCGTGAG chr1:167191653-167191733 41 4.29e-04 TACATTCGCC CCATGTGC TTTTGTGGTT chr12:104354526-10435460 37 4.83e-04 ctgtcaaaca ccatgtgt ccgtggtgat chr12:26267443-26267523 31 4.83e-04 ATGTGCGGGC ACACGTGA CAGCGCCGCG chr11:45868783-45868863 43 4.83e-04 GGGCGGACCC ACACATGG TAGGAACGTG chr16:89283045-89283125 70 4.94e-04 tgaacacttc acaTGTGg ttt chr1:25758746-25758826 23 5.14e-04 TGTACACCTT GCACATGC TCTTGTTTAC chr22:29949800-29949880 47 5.56e-04 AAAAACAAAG ACACATGC Ttctcgttca chr10:102747302-10274738 20 5.56e-04 AAGGCGAGTA GCATGTGC GGGAGACTCA chr3:67048544-67048624 62 5.56e-04 TTCCCGACAC GCATGTGC TCGCGTCGTG chr12:53765220-53765300 30 6.20e-04 CCTCTGGGCA CCTCGTGG CCCGGGCAGG chr17:75316972-75317052 1 6.20e-04 . gcatgtgt gtgcgtgtgt chr15:85143708-85143788 36 6.20e-04 AAGACCGGGT GCATGTGT ACAGCTGCAA chr19:14115774-14115854 58 6.26e-04 TGACACAAAA ACATGTGT CTGGCCAAGA chr1:44457189-44457269 73 6.87e-04 CGGGTGATGG CCACGCGG chr10:120924970-12092505 22 6.87e-04 cagcccgact ccacgcgg cccggcccgc chr7:155090786-155090866 65 7.09e-04 AACAAACCCG TCACATGG GTTCAGGA chr9:73029013-73029093 30 7.56e-04 CGTTTCGCTG CCTCGTGC TACCCCTACA chr5:175815548-175815628 44 8.22e-04 GTCTCTCAGA CCTCGTGT AACAAACTCC chr11:77531990-77532070 46 8.22e-04 CTTGCCACTG CCTCGTGT GACAGGGGGA chr12:131324045-13132412 73 9.25e-04 CTTTAAGGGT CCACGCGC chr1:6661285-6661365 62 9.25e-04 AGCCTAAACA CCATGTGA CCAGAGCACA chr8:95907981-95908061 55 9.25e-04 CACCACTCAG CCACGCGC CTGGCCAAGT chr12:104682569-10468264 30 1.02e-03 TCAACAGAGG GCACGCGG TGCCTGCGGG chr3:69788420-69788500 19 1.09e-03 GCGGTGTCCA CCACGTTG CCTCTCCCCC chr3:183353354-183353434 42 1.10e-03 GCCCGGACGG TCACATGT TTCCTTTGTT chr3:38495175-38495255 32 1.31e-03 GCAAGTTGGT GCACGCGC GTCCTCCCAC chr19:47733585-47733665 24 1.42e-03 ACAACCCCGC ACACGCGC GCTCCCACGG chr11:123940245-12394032 41 1.60e-03 ggggctccga cctcatgg cagcgtctaa -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCACGTGS MEME-1 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr1:31628299-31628379 3.5e-05 46_[+1]_26 chr7:77485128-77485208 3.5e-05 24_[+1]_48 chr11:71159706-71159786 3.5e-05 14_[+1]_58 chr1:159750735-159750815 3.5e-05 19_[+1]_53 chr19:50180739-50180819 3.5e-05 58_[+1]_14 chr10:50747182-50747262 3.5e-05 27_[+1]_45 chr12:8380264-8380344 3.5e-05 11_[+1]_61 chrX:153991776-153991856 3.5e-05 23_[+1]_49 chr14:77279230-77279310 3.5e-05 25_[+1]_47 chr4:83351705-83351785 3.5e-05 30_[+1]_42 chr5:170815538-170815618 3.5e-05 49_[+1]_23 chr12:120755569-12075564 3.5e-05 52_[+1]_20 chr19:13096198-13096278 3.5e-05 44_[+1]_28 chr5:90628226-90628306 3.5e-05 37_[+1]_35 chr10:75911098-75911178 3.5e-05 58_[+1]_14 chr1:211752937-211753017 3.5e-05 29_[+1]_43 chr12:50813523-50813603 3.5e-05 21_[+1]_51 chr11:119252508-11925258 3.5e-05 23_[+1]_49 chr10:99161011-99161091 3.5e-05 47_[+1]_25 chr17:38269599-38269679 3.5e-05 66_[+1]_6 chr16:58549328-58549408 3.5e-05 25_[+1]_47 chr11:537305-537385 3.5e-05 60_[+1]_12 chr12:62654825-62654905 3.5e-05 67_[+1]_5 chr19:2151825-2151905 3.5e-05 64_[+1]_8 chr19:2346177-2346257 3.5e-05 53_[+1]_19 chr16:27246710-27246790 3.5e-05 60_[+1]_12 chr8:99129449-99129529 3.5e-05 42_[+1]_30 chr16:22960172-22960252 3.5e-05 40_[+1]_32 chr7:65580511-65580591 3.5e-05 67_[+1]_5 chr11:118851021-11885110 3.5e-05 4_[+1]_68 chr17:33307430-33307510 3.5e-05 27_[+1]_45 chr1:110162327-110162407 3.5e-05 53_[+1]_19 chr9:140429452-140429532 3.5e-05 47_[+1]_25 chr17:66453941-66454021 3.5e-05 45_[+1]_27 chr16:29605738-29605818 3.5e-05 12_[+1]_60 chr9:127963007-127963087 3.5e-05 56_[+1]_16 chr10:11916876-11916956 3.5e-05 42_[+1]_30 chr19:18452167-18452247 3.5e-05 51_[+1]_21 chr10:104001484-10400156 3.5e-05 19_[+1]_53 chr17:5323318-5323398 3.5e-05 68_[+1]_4 chr1:24120008-24120088 3.5e-05 36_[+1]_36 chr20:39657118-39657198 3.5e-05 23_[+1]_49 chr3:49966997-49967077 3.5e-05 19_[+1]_53 chr10:104474508-10447458 3.5e-05 60_[+1]_12 chr10:103893360-10389344 3.5e-05 39_[+1]_33 chr16:74402183-74402263 3.5e-05 40_[+1]_32 chr2:11919416-11919496 3.5e-05 32_[+1]_40 chr8:124553528-124553608 3.5e-05 18_[+1]_54 chr21:47609219-47609299 3.5e-05 20_[+1]_52 chr16:70148043-70148123 3.5e-05 31_[+1]_41 chr12:48152906-48152986 3.5e-05 46_[+1]_26 chr3:182817397-182817477 6.9e-05 47_[+1]_25 chr2:88991322-88991402 6.9e-05 10_[+1]_62 chr22:41763217-41763297 6.9e-05 45_[+1]_27 chr4:17579035-17579115 6.9e-05 9_[+1]_63 chrX:129216521-129216601 6.9e-05 21_[+1]_51 chr7:30323892-30323972 6.9e-05 35_[+1]_37 chr19:7570833-7570913 6.9e-05 45_[+1]_27 chr16:88877868-88877948 6.9e-05 25_[+1]_47 chr17:58754771-58754851 6.9e-05 10_[+1]_62 chr16:89766698-89766778 6.9e-05 40_[+1]_32 chr17:17109832-17109912 6.9e-05 64_[+1]_8 chr11:107729295-10772937 6.9e-05 19_[+1]_53 chr1:155243341-155243421 6.9e-05 19_[+1]_53 chr19:2977363-2977443 6.9e-05 57_[+1]_15 chr19:18350288-18350368 6.9e-05 42_[+1]_30 chr1:12203863-12203943 6.9e-05 38_[+1]_34 chr19:45909116-45909196 6.9e-05 25_[+1]_47 chr6:42016722-42016802 6.9e-05 4_[+1]_68 chr19:1672499-1672579 6.9e-05 22_[+1]_50 chr19:49655096-49655176 6.9e-05 22_[+1]_50 chr11:3663824-3663904 6.9e-05 14_[+1]_58 chr4:87952118-87952198 6.9e-05 31_[+1]_41 chr12:122461414-12246149 6.9e-05 21_[+1]_51 chr3:186648864-186648944 6.9e-05 18_[+1]_54 chr4:57302508-57302588 6.9e-05 47_[+1]_25 chr17:2303883-2303963 6.9e-05 49_[+1]_23 chr15:41407817-41407897 6.9e-05 48_[+1]_24 chr11:9594378-9594458 6.9e-05 16_[+1]_56 chr8:144025193-144025273 6.9e-05 53_[+1]_19 chr4:186317807-186317887 6.9e-05 24_[+1]_48 chr17:49336702-49336782 6.9e-05 27_[+1]_45 chr9:35116316-35116396 6.9e-05 55_[+1]_17 chr4:90032286-90032366 6.9e-05 16_[+1]_56 chr19:30335300-30335380 6.9e-05 57_[+1]_15 chr4:4291771-4291851 0.00012 34_[+1]_38 chr6:97345678-97345758 0.00012 32_[+1]_40 chr4:103266662-103266742 0.00012 38_[+1]_34 chr16:69166527-69166607 0.00012 7_[+1]_65 chr19:4968834-4968914 0.00012 47_[+1]_25 chr9:140565420-140565500 0.00012 47_[+1]_25 chr22:24181346-24181426 0.00012 49_[+1]_23 chr1:31654643-31654723 0.00012 59_[+1]_13 chr19:41903292-41903372 0.00012 54_[+1]_18 chr1:33501781-33501861 0.00012 68_[+1]_4 chr4:110736922-110737002 0.00012 25_[+1]_47 chr12:113659616-11365969 0.00012 65_[+1]_7 chr3:183967325-183967405 0.00012 36_[+1]_36 chr17:38255627-38255707 0.00012 63_[+1]_9 chr5:154062178-154062258 0.00012 3_[+1]_69 chr4:57301611-57301691 0.00012 45_[+1]_27 chr7:100450152-100450232 0.00012 64_[+1]_8 chr1:44445511-44445591 0.00012 33_[+1]_39 chr4:109087760-109087840 0.00012 21_[+1]_51 chr17:36831359-36831439 0.00012 72_[+1] chr5:176739254-176739334 0.00012 21_[+1]_51 chr17:34890805-34890885 0.00012 26_[+1]_46 chr4:2264036-2264116 0.00012 31_[+1]_41 chr17:8055855-8055935 0.00012 33_[+1]_39 chr2:85766880-85766960 0.00012 49_[+1]_23 chr16:88519030-88519110 0.00012 58_[+1]_14 chr2:75062121-75062201 0.00012 25_[+1]_47 chr2:232328534-232328614 0.00012 27_[+1]_45 chr4:52710951-52711031 0.00012 36_[+1]_36 chr17:4268536-4268616 0.00012 38_[+1]_34 chr3:167814046-167814126 0.00012 42_[+1]_30 chr5:139927199-139927279 0.00012 33_[+1]_39 chr16:30418599-30418679 0.00012 6_[+1]_66 chr17:42404342-42404422 0.00012 26_[+1]_46 chr15:85524117-85524197 0.00012 55_[+1]_17 chr15:68522409-68522489 0.00012 52_[+1]_20 chr19:55691518-55691598 0.00012 36_[+1]_36 chr11:66336092-66336172 0.00012 29_[+1]_43 chr11:114310015-11431009 0.00014 8_[+1]_64 chr3:50563567-50563647 0.00014 33_[+1]_39 chr19:5341040-5341120 0.00014 16_[+1]_56 chr16:75267965-75268045 0.00014 21_[+1]_51 chr3:122512698-122512778 0.00014 52_[+1]_20 chr17:4635124-4635204 0.00014 31_[+1]_41 chr17:71088795-71088875 0.00014 52_[+1]_20 chr20:305106-305186 0.00014 27_[+1]_45 chr11:94226537-94226617 0.00014 16_[+1]_56 chr8:145800926-145801006 0.00014 45_[+1]_27 chr12:120763357-12076343 0.00014 28_[+1]_44 chr17:7184770-7184850 0.00014 4_[+1]_68 chr12:56513308-56513388 0.00014 50_[+1]_22 chr22:40742713-40742793 0.00018 53_[+1]_19 chr15:98503705-98503785 0.00018 16_[+1]_56 chr10:26986846-26986926 0.00018 7_[+1]_65 chr17:53315698-53315778 0.00018 49_[+1]_23 chr9:140563962-140564042 0.00018 43_[+1]_29 chr20:42839576-42839656 0.00018 30_[+1]_42 chr3:66271349-66271429 0.00018 26_[+1]_46 chr19:55768869-55768949 0.00018 54_[+1]_18 chr16:14728077-14728157 0.00018 22_[+1]_50 chr19:50037104-50037184 0.00018 24_[+1]_48 chr19:36605861-36605941 0.00022 9_[+1]_63 chr8:103425154-103425234 0.00022 35_[+1]_37 chr21:46961665-46961745 0.00022 56_[+1]_16 chr1:6454167-6454247 0.00022 31_[+1]_41 chr5:78642360-78642440 0.00022 67_[+1]_5 chr2:68385006-68385086 0.00022 21_[+1]_51 chr2:191746736-191746816 0.00022 28_[+1]_44 chr9:6007106-6007186 0.00022 27_[+1]_45 chr11:120894731-12089481 0.00022 35_[+1]_37 chr8:81397755-81397835 0.00022 24_[+1]_48 chr1:156251164-156251244 0.00022 40_[+1]_32 chr18:23807913-23807993 0.00022 32_[+1]_40 chr19:10400007-10400087 0.00023 50_[+1]_22 chr17:4458609-4458689 0.00023 36_[+1]_36 chr12:123848118-12384819 0.00023 24_[+1]_48 chr16:3202254-3202334 0.00023 39_[+1]_33 chr19:17580250-17580330 0.00023 61_[+1]_11 chr9:132020876-132020956 0.00023 10_[+1]_62 chr5:172410732-172410812 0.00025 13_[+1]_59 chr8:26240466-26240546 0.00025 32_[+1]_40 chr2:30369408-30369488 0.00025 23_[+1]_49 chr9:140444862-140444942 0.00025 27_[+1]_45 chr16:79867620-79867700 0.00029 5_[+1]_67 chr22:39541778-39541858 0.00029 4_[+1]_68 chr12:49463690-49463770 0.00029 43_[+1]_29 chr11:65624483-65624563 0.00029 15_[+1]_57 chr17:2305017-2305097 0.00029 22_[+1]_50 chr17:44269101-44269181 0.00029 46_[+1]_26 chr21:33765248-33765328 0.00029 60_[+1]_12 chr16:56966970-56967050 0.00029 44_[+1]_28 chr19:30433691-30433771 0.00033 9_[+1]_63 chr20:44992642-44992722 0.00034 32_[+1]_40 chr17:25853698-25853778 0.00034 54_[+1]_18 chrX:106920099-106920179 0.00036 26_[+1]_46 chr15:75497201-75497281 0.00043 [+1]_72 chr19:1847775-1847855 0.00043 32_[+1]_40 chr6:11112062-11112142 0.00043 24_[+1]_48 chr2:239197523-239197603 0.00043 59_[+1]_13 chr5:175963612-175963692 0.00043 31_[+1]_41 chr1:167191653-167191733 0.00043 40_[+1]_32 chr12:104354526-10435460 0.00048 36_[+1]_36 chr12:26267443-26267523 0.00048 30_[+1]_42 chr11:45868783-45868863 0.00048 42_[+1]_30 chr16:89283045-89283125 0.00049 69_[+1]_3 chr1:25758746-25758826 0.00051 22_[+1]_50 chr22:29949800-29949880 0.00056 46_[+1]_26 chr10:102747302-10274738 0.00056 19_[+1]_53 chr3:67048544-67048624 0.00056 61_[+1]_11 chr12:53765220-53765300 0.00062 29_[+1]_43 chr17:75316972-75317052 0.00062 [+1]_72 chr15:85143708-85143788 0.00062 35_[+1]_37 chr19:14115774-14115854 0.00063 57_[+1]_15 chr1:44457189-44457269 0.00069 72_[+1] chr10:120924970-12092505 0.00069 21_[+1]_51 chr7:155090786-155090866 0.00071 64_[+1]_8 chr9:73029013-73029093 0.00076 29_[+1]_43 chr5:175815548-175815628 0.00082 43_[+1]_29 chr11:77531990-77532070 0.00082 45_[+1]_27 chr12:131324045-13132412 0.00092 72_[+1] chr1:6661285-6661365 0.00092 61_[+1]_11 chr8:95907981-95908061 0.00092 54_[+1]_18 chr12:104682569-10468264 0.001 29_[+1]_43 chr3:69788420-69788500 0.0011 18_[+1]_54 chr3:183353354-183353434 0.0011 41_[+1]_31 chr3:38495175-38495255 0.0013 31_[+1]_41 chr19:47733585-47733665 0.0014 23_[+1]_49 chr11:123940245-12394032 0.0016 40_[+1]_32 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCACGTGS MEME-1 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF CCACGTGS width=8 seqs=213 chr1:31628299-31628379 ( 47) CCACGTGG 1 chr7:77485128-77485208 ( 25) CCACGTGG 1 chr11:71159706-71159786 ( 15) CCACGTGG 1 chr1:159750735-159750815 ( 20) CCACGTGG 1 chr19:50180739-50180819 ( 59) CCACGTGG 1 chr10:50747182-50747262 ( 28) CCACGTGG 1 chr12:8380264-8380344 ( 12) CCACGTGG 1 chrX:153991776-153991856 ( 24) CCACGTGG 1 chr14:77279230-77279310 ( 26) CCACGTGG 1 chr4:83351705-83351785 ( 31) CCACGTGG 1 chr5:170815538-170815618 ( 50) CCACGTGG 1 chr12:120755569-12075564 ( 53) CCACGTGG 1 chr19:13096198-13096278 ( 45) CCACGTGG 1 chr5:90628226-90628306 ( 38) CCACGTGG 1 chr10:75911098-75911178 ( 59) CCACGTGG 1 chr1:211752937-211753017 ( 30) CCACGTGG 1 chr12:50813523-50813603 ( 22) CCACGTGG 1 chr11:119252508-11925258 ( 24) CCACGTGG 1 chr10:99161011-99161091 ( 48) CCACGTGG 1 chr17:38269599-38269679 ( 67) CCACGTGG 1 chr16:58549328-58549408 ( 26) CCACGTGG 1 chr11:537305-537385 ( 61) CCACGTGG 1 chr12:62654825-62654905 ( 68) CCACGTGG 1 chr19:2151825-2151905 ( 65) CCACGTGG 1 chr19:2346177-2346257 ( 54) CCACGTGG 1 chr16:27246710-27246790 ( 61) CCACGTGG 1 chr8:99129449-99129529 ( 43) CCACGTGG 1 chr16:22960172-22960252 ( 41) CCACGTGG 1 chr7:65580511-65580591 ( 68) CCACGTGG 1 chr11:118851021-11885110 ( 5) CCACGTGG 1 chr17:33307430-33307510 ( 28) CCACGTGG 1 chr1:110162327-110162407 ( 54) CCACGTGG 1 chr9:140429452-140429532 ( 48) CCACGTGG 1 chr17:66453941-66454021 ( 46) CCACGTGG 1 chr16:29605738-29605818 ( 13) CCACGTGG 1 chr9:127963007-127963087 ( 57) CCACGTGG 1 chr10:11916876-11916956 ( 43) CCACGTGG 1 chr19:18452167-18452247 ( 52) CCACGTGG 1 chr10:104001484-10400156 ( 20) CCACGTGG 1 chr17:5323318-5323398 ( 69) CCACGTGG 1 chr1:24120008-24120088 ( 37) CCACGTGG 1 chr20:39657118-39657198 ( 24) CCACGTGG 1 chr3:49966997-49967077 ( 20) CCACGTGG 1 chr10:104474508-10447458 ( 61) CCACGTGG 1 chr10:103893360-10389344 ( 40) CCACGTGG 1 chr16:74402183-74402263 ( 41) CCACGTGG 1 chr2:11919416-11919496 ( 33) CCACGTGG 1 chr8:124553528-124553608 ( 19) CCACGTGG 1 chr21:47609219-47609299 ( 21) CCACGTGG 1 chr16:70148043-70148123 ( 32) CCACGTGG 1 chr12:48152906-48152986 ( 47) CCACGTGG 1 chr3:182817397-182817477 ( 48) CCACGTGC 1 chr2:88991322-88991402 ( 11) CCACGTGC 1 chr22:41763217-41763297 ( 46) CCACGTGC 1 chr4:17579035-17579115 ( 10) CCACGTGC 1 chrX:129216521-129216601 ( 22) CCACGTGC 1 chr7:30323892-30323972 ( 36) CCACGTGC 1 chr19:7570833-7570913 ( 46) CCACGTGC 1 chr16:88877868-88877948 ( 26) CCACGTGC 1 chr17:58754771-58754851 ( 11) CCACGTGC 1 chr16:89766698-89766778 ( 41) CCACGTGC 1 chr17:17109832-17109912 ( 65) CCACGTGC 1 chr11:107729295-10772937 ( 20) CCACGTGC 1 chr1:155243341-155243421 ( 20) CCACGTGC 1 chr19:2977363-2977443 ( 58) CCACGTGC 1 chr19:18350288-18350368 ( 43) CCACGTGC 1 chr1:12203863-12203943 ( 39) CCACGTGC 1 chr19:45909116-45909196 ( 26) CCACGTGC 1 chr6:42016722-42016802 ( 5) CCACGTGC 1 chr19:1672499-1672579 ( 23) CCACGTGC 1 chr19:49655096-49655176 ( 23) CCACGTGC 1 chr11:3663824-3663904 ( 15) CCACGTGC 1 chr4:87952118-87952198 ( 32) CCACGTGC 1 chr12:122461414-12246149 ( 22) CCACGTGC 1 chr3:186648864-186648944 ( 19) CCACGTGC 1 chr4:57302508-57302588 ( 48) CCACGTGC 1 chr17:2303883-2303963 ( 50) CCACGTGC 1 chr15:41407817-41407897 ( 49) CCACGTGC 1 chr11:9594378-9594458 ( 17) CCACGTGC 1 chr8:144025193-144025273 ( 54) CCACGTGC 1 chr4:186317807-186317887 ( 25) CCACGTGC 1 chr17:49336702-49336782 ( 28) CCACGTGC 1 chr9:35116316-35116396 ( 56) CCACGTGC 1 chr4:90032286-90032366 ( 17) CCACGTGC 1 chr19:30335300-30335380 ( 58) CCACGTGC 1 chr4:4291771-4291851 ( 35) GCACGTGG 1 chr6:97345678-97345758 ( 33) GCACGTGG 1 chr4:103266662-103266742 ( 39) GCACGTGG 1 chr16:69166527-69166607 ( 8) GCACGTGG 1 chr19:4968834-4968914 ( 48) GCACGTGG 1 chr9:140565420-140565500 ( 48) GCACGTGG 1 chr22:24181346-24181426 ( 50) GCACGTGG 1 chr1:31654643-31654723 ( 60) CCACGTGT 1 chr19:41903292-41903372 ( 55) GCACGTGG 1 chr1:33501781-33501861 ( 69) CCACGTGT 1 chr4:110736922-110737002 ( 26) GCACGTGG 1 chr12:113659616-11365969 ( 66) GCACGTGG 1 chr3:183967325-183967405 ( 37) CCACGTGT 1 chr17:38255627-38255707 ( 64) GCACGTGG 1 chr5:154062178-154062258 ( 4) CCACGTGT 1 chr4:57301611-57301691 ( 46) GCACGTGG 1 chr7:100450152-100450232 ( 65) GCACGTGG 1 chr1:44445511-44445591 ( 34) CCACGTGT 1 chr4:109087760-109087840 ( 22) CCACGTGT 1 chr17:36831359-36831439 ( 73) GCACGTGG 1 chr5:176739254-176739334 ( 22) GCACGTGG 1 chr17:34890805-34890885 ( 27) GCACGTGG 1 chr4:2264036-2264116 ( 32) GCACGTGG 1 chr17:8055855-8055935 ( 34) GCACGTGG 1 chr2:85766880-85766960 ( 50) CCACGTGT 1 chr16:88519030-88519110 ( 59) GCACGTGG 1 chr2:75062121-75062201 ( 26) GCACGTGG 1 chr2:232328534-232328614 ( 28) CCACGTGT 1 chr4:52710951-52711031 ( 37) GCACGTGG 1 chr17:4268536-4268616 ( 39) GCACGTGG 1 chr3:167814046-167814126 ( 43) GCACGTGG 1 chr5:139927199-139927279 ( 34) GCACGTGG 1 chr16:30418599-30418679 ( 7) GCACGTGG 1 chr17:42404342-42404422 ( 27) GCACGTGG 1 chr15:85524117-85524197 ( 56) GCACGTGG 1 chr15:68522409-68522489 ( 53) GCACGTGG 1 chr19:55691518-55691598 ( 37) GCACGTGG 1 chr11:66336092-66336172 ( 30) GCACGTGG 1 chr11:114310015-11431009 ( 9) ACACGTGG 1 chr3:50563567-50563647 ( 34) ACACGTGG 1 chr19:5341040-5341120 ( 17) ACACGTGG 1 chr16:75267965-75268045 ( 22) ACACGTGG 1 chr3:122512698-122512778 ( 53) ACACGTGG 1 chr17:4635124-4635204 ( 32) ACACGTGG 1 chr17:71088795-71088875 ( 53) ACACGTGG 1 chr20:305106-305186 ( 28) ACACGTGG 1 chr11:94226537-94226617 ( 17) ACACGTGG 1 chr8:145800926-145801006 ( 46) ACACGTGG 1 chr12:120763357-12076343 ( 29) ACACGTGG 1 chr17:7184770-7184850 ( 5) ACACGTGG 1 chr12:56513308-56513388 ( 51) ACACGTGG 1 chr22:40742713-40742793 ( 54) GCACGTGC 1 chr15:98503705-98503785 ( 17) GCACGTGC 1 chr10:26986846-26986926 ( 8) GCACGTGC 1 chr17:53315698-53315778 ( 50) GCACGTGC 1 chr9:140563962-140564042 ( 44) GCACGTGC 1 chr20:42839576-42839656 ( 31) GCACGTGC 1 chr3:66271349-66271429 ( 27) GCACGTGC 1 chr19:55768869-55768949 ( 55) GCACGTGC 1 chr16:14728077-14728157 ( 23) GCACGTGC 1 chr19:50037104-50037184 ( 25) GCACGTGC 1 chr19:36605861-36605941 ( 10) ACACGTGC 1 chr8:103425154-103425234 ( 36) GCACGTGT 1 chr21:46961665-46961745 ( 57) ACACGTGC 1 chr1:6454167-6454247 ( 32) GCACGTGT 1 chr5:78642360-78642440 ( 68) GCACGTGT 1 chr2:68385006-68385086 ( 22) GCACGTGT 1 chr2:191746736-191746816 ( 29) GCACGTGT 1 chr9:6007106-6007186 ( 28) GCACGTGT 1 chr11:120894731-12089481 ( 36) ACACGTGC 1 chr8:81397755-81397835 ( 25) GCACGTGT 1 chr1:156251164-156251244 ( 41) ACACGTGC 1 chr18:23807913-23807993 ( 33) ACACGTGC 1 chr19:10400007-10400087 ( 51) ACACGTGT 1 chr17:4458609-4458689 ( 37) ACACGTGT 1 chr12:123848118-12384819 ( 25) ACACGTGT 1 chr16:3202254-3202334 ( 40) ACACGTGT 1 chr19:17580250-17580330 ( 62) ACACGTGT 1 chr9:132020876-132020956 ( 11) ACACGTGT 1 chr5:172410732-172410812 ( 14) TCACGTGG 1 chr8:26240466-26240546 ( 33) TCACGTGG 1 chr2:30369408-30369488 ( 24) TCACGTGG 1 chr9:140444862-140444942 ( 28) TCACGTGG 1 chr16:79867620-79867700 ( 6) CCACATGG 1 chr22:39541778-39541858 ( 5) CCACGTGA 1 chr12:49463690-49463770 ( 44) CCACGTGA 1 chr11:65624483-65624563 ( 16) CCACGTGA 1 chr17:2305017-2305097 ( 23) CCACATGG 1 chr17:44269101-44269181 ( 47) CCACGTGA 1 chr21:33765248-33765328 ( 61) CCACATGG 1 chr16:56966970-56967050 ( 45) CCACGTGA 1 chr19:30433691-30433771 ( 10) TCACGTGC 1 chr20:44992642-44992722 ( 33) TCACGTGT 1 chr17:25853698-25853778 ( 55) TCACGTGT 1 chrX:106920099-106920179 ( 27) CCACATGC 1 chr15:75497201-75497281 ( 1) CCATGTGC 1 chr19:1847775-1847855 ( 33) GCACATGG 1 chr6:11112062-11112142 ( 25) CCACATGT 1 chr2:239197523-239197603 ( 60) GCACATGG 1 chr5:175963612-175963692 ( 32) CCATGTGC 1 chr1:167191653-167191733 ( 41) CCATGTGC 1 chr12:104354526-10435460 ( 37) CCATGTGT 1 chr12:26267443-26267523 ( 31) ACACGTGA 1 chr11:45868783-45868863 ( 43) ACACATGG 1 chr16:89283045-89283125 ( 70) ACATGTGG 1 chr1:25758746-25758826 ( 23) GCACATGC 1 chr22:29949800-29949880 ( 47) ACACATGC 1 chr10:102747302-10274738 ( 20) GCATGTGC 1 chr3:67048544-67048624 ( 62) GCATGTGC 1 chr12:53765220-53765300 ( 30) CCTCGTGG 1 chr17:75316972-75317052 ( 1) GCATGTGT 1 chr15:85143708-85143788 ( 36) GCATGTGT 1 chr19:14115774-14115854 ( 58) ACATGTGT 1 chr1:44457189-44457269 ( 73) CCACGCGG 1 chr10:120924970-12092505 ( 22) CCACGCGG 1 chr7:155090786-155090866 ( 65) TCACATGG 1 chr9:73029013-73029093 ( 30) CCTCGTGC 1 chr5:175815548-175815628 ( 44) CCTCGTGT 1 chr11:77531990-77532070 ( 46) CCTCGTGT 1 chr12:131324045-13132412 ( 73) CCACGCGC 1 chr1:6661285-6661365 ( 62) CCATGTGA 1 chr8:95907981-95908061 ( 55) CCACGCGC 1 chr12:104682569-10468264 ( 30) GCACGCGG 1 chr3:69788420-69788500 ( 19) CCACGTTG 1 chr3:183353354-183353434 ( 42) TCACATGT 1 chr3:38495175-38495255 ( 32) GCACGCGC 1 chr19:47733585-47733665 ( 24) ACACGCGC 1 chr11:123940245-12394032 ( 41) CCTCATGG 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCACGTGS MEME-1 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 6.96419 E= 1.2e-238 -36 79 -28 -210 -1438 165 -1438 -1438 243 -1438 -1438 -295 -1438 157 -1438 -181 -157 -1438 156 -1438 -1438 -328 -1438 241 -1438 -1438 164 -527 -246 -11 72 -32 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCACGTGS MEME-1 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 213 E= 1.2e-238 0.140845 0.553991 0.262911 0.042254 0.000000 1.000000 0.000000 0.000000 0.976526 0.000000 0.000000 0.023474 0.000000 0.948357 0.000000 0.051643 0.061033 0.000000 0.938967 0.000000 0.000000 0.032864 0.000000 0.967136 0.000000 0.000000 0.995305 0.004695 0.032864 0.295775 0.525822 0.145540 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCACGTGS MEME-1 regular expression -------------------------------------------------------------------------------- [CG]CACGTG[GC] -------------------------------------------------------------------------------- Time 4.89 secs. ******************************************************************************** ******************************************************************************** MOTIF HAAACAAR MEME-2 width = 8 sites = 49 llr = 396 E-value = 1.1e-010 ******************************************************************************** -------------------------------------------------------------------------------- Motif HAAACAAR MEME-2 Description -------------------------------------------------------------------------------- Simplified A 38aa:a64 pos.-specific C 22::9:21 probability G 1:::::24 matrix T 4:::1::1 bits 2.5 ** * 2.2 ** * 2.0 ** * 1.7 *** * Relative 1.5 *** * Entropy 1.2 *** * (11.7 bits) 1.0 ***** 0.7 ****** 0.5 ******* 0.2 ******** 0.0 -------- Multilevel TAAACAAA consensus A CG sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif HAAACAAR MEME-2 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr22:29949800-29949880 38 4.07e-06 TGAGACTGTA AAAACAAA GACACATGCT chr12:50813523-50813603 4 4.07e-06 aca aaaacaaa aacaacctat chr17:38255627-38255707 52 4.07e-06 CTGCTGAATG AAAACAAA CGCAGCACGT chr17:44269101-44269181 16 4.07e-06 CACACACCCC AAAACAAA CAAAAAAACA chr15:85143708-85143788 8 4.07e-06 ACGTGCG AAAACAAA GGGGTGTGCG chr7:155090786-155090866 53 4.07e-06 TGGATAACTG AAAACAAA CCCGTCACAT chr22:39541778-39541858 39 7.67e-06 CACGGCCGGG TAAACAAG CCCCGGCCGC chr19:1847775-1847855 14 7.67e-06 GTCATGGAAA TAAACAAG GGCGGCCACA chr12:49463690-49463770 18 1.12e-05 GAAGGAAACC AAAACAAG CGCCGCGCCC chr11:77531990-77532070 67 1.12e-05 AGGGGGAATG AAAACAAG GGAAGC chr12:104354526-10435460 62 1.84e-05 gatgctggtg taaacaca ccatgctgcc chr1:24120008-24120088 65 1.84e-05 GGCAACACCT TAAACACA GGCCCTGC chr11:94226537-94226617 6 2.32e-05 GAGTG TAAATAAA CAAACACGTG chr5:90628226-90628306 53 3.00e-05 tggtcagtgc taaacaat gaaatgtgag chr10:99094492-99094572 17 3.00e-05 GGTTGATTTG TAAACAAT GGGTGACGTC chr17:58754771-58754851 55 4.19e-05 GAATTCGATG TAAACAGA CCAGTCTCCC chr19:18350288-18350368 30 4.19e-05 tgttgatgat aaaacaat gggacccacg chr16:70148043-70148123 23 4.19e-05 TCGCGAGACC CAAACAAG CCCACGTGGC chr12:48152906-48152986 70 4.19e-05 AGGAGAAATG CAAACAAG GAA chr11:9594378-9594458 38 5.18e-05 CGAACAAATG TAAACACG GAGATCGTGT chr4:90032286-90032366 7 5.18e-05 TGTTTG TAAACACG CCCCACGTGC chr12:120755569-12075564 44 6.38e-05 CACGAAAAGG TAAATAAG GCCACGTGGC chr6:42016722-42016802 24 7.93e-05 ATCCAGGAAG TAAACAAC ATCATGAGGA chr3:186648864-186648944 10 7.93e-05 TGCGGATCC ACAACAAA CCCACGTGCG chr19:46270851-46270931 11 7.93e-05 TTCACGTTTC ACAACAAA GGCAGAAGAC chr17:37558909-37558989 32 7.93e-05 TTTGGCGGGA GAAACAAG CGTGTGTGAG chr5:175963612-175963692 59 7.93e-05 GACAAAAGCA ACAACAAA GGAAGTGGCG chr1:3541337-3541417 13 9.04e-05 TCTCGTTGTG TAAACAGG AAGTGAGCCT chr16:58549328-58549408 16 9.78e-05 CGTGGACGAC AAAACAGG CACCACGTGG chr21:47609219-47609299 50 9.78e-05 TGGGCTGAGA AAAAAAAA CAGCATGTGC chrX:129216521-129216601 2 1.04e-04 C CAAACACA CCTCCTCTCG chr1:211752937-211753017 1 1.41e-04 . CAAACAGA CTTTGATCCT chr16:3202254-3202334 23 1.41e-04 ACAGATTTTT TAAAAAAG GAAAATAACA chr18:23807913-23807993 50 1.41e-04 CCACAGTTGA CAAACAGA TCAGTCATGC chr1:44457189-44457269 18 1.65e-04 CCCGCCGGAC CAAACACG GGAGGGGGCG chr5:175815548-175815628 18 1.65e-04 ACCAGCAGCT CAAACACG CTGCCTCTGT chr4:103266662-103266742 2 1.81e-04 A CAAATAAG GGGAGGAGGG chr2:191746736-191746816 56 1.81e-04 TGGGGCACCG GAAACAAT GTTTCAGAAG chr17:4458609-4458689 27 2.56e-04 CACACTCACC GAAACACG AAACACGTGT chr3:12909893-12909973 51 2.56e-04 cctccgctgc caaacagg gaagggcccc chr10:99161011-99161091 32 2.56e-04 CAGGGACGTA GAAACACG CTCAGAACCC chr12:122461414-12246149 12 2.56e-04 AAGAGGAAAA TCAATAAA GTCCACGTGC chr8:95907981-95908061 41 2.56e-04 CTGCAGAATG TAAACACC ACTCAGCCAC chr16:22960172-22960252 56 2.76e-04 TGGCTTAACA GCAACAAA GGTGACAGAT chr12:104682569-10468264 20 3.17e-04 TGCAAGGGAG TCAACAGA GGGCACGCGG chr9:140444862-140444942 18 3.46e-04 CTTCCCTCTG TAAACAGC CCTCACGTGG chr17:2305017-2305097 2 3.90e-04 G ACAACACG GCATGGAGCA chr14:77279230-77279310 52 4.31e-04 CCGCGCTTCA ACAACAAC TTTATTGGGA chr3:122512698-122512778 44 4.55e-04 CCCGGGTGTG GAAATACA AACACGTGGT -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif HAAACAAR MEME-2 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr22:29949800-29949880 4.1e-06 37_[+2]_35 chr12:50813523-50813603 4.1e-06 3_[+2]_69 chr17:38255627-38255707 4.1e-06 51_[+2]_21 chr17:44269101-44269181 4.1e-06 15_[+2]_57 chr15:85143708-85143788 4.1e-06 7_[+2]_65 chr7:155090786-155090866 4.1e-06 52_[+2]_20 chr22:39541778-39541858 7.7e-06 38_[+2]_34 chr19:1847775-1847855 7.7e-06 13_[+2]_59 chr12:49463690-49463770 1.1e-05 17_[+2]_55 chr11:77531990-77532070 1.1e-05 66_[+2]_6 chr12:104354526-10435460 1.8e-05 61_[+2]_11 chr1:24120008-24120088 1.8e-05 64_[+2]_8 chr11:94226537-94226617 2.3e-05 5_[+2]_67 chr5:90628226-90628306 3e-05 52_[+2]_20 chr10:99094492-99094572 3e-05 16_[+2]_56 chr17:58754771-58754851 4.2e-05 54_[+2]_18 chr19:18350288-18350368 4.2e-05 29_[+2]_43 chr16:70148043-70148123 4.2e-05 22_[+2]_50 chr12:48152906-48152986 4.2e-05 69_[+2]_3 chr11:9594378-9594458 5.2e-05 37_[+2]_35 chr4:90032286-90032366 5.2e-05 6_[+2]_66 chr12:120755569-12075564 6.4e-05 43_[+2]_29 chr6:42016722-42016802 7.9e-05 23_[+2]_49 chr3:186648864-186648944 7.9e-05 9_[+2]_63 chr19:46270851-46270931 7.9e-05 10_[+2]_62 chr17:37558909-37558989 7.9e-05 31_[+2]_41 chr5:175963612-175963692 7.9e-05 58_[+2]_14 chr1:3541337-3541417 9e-05 12_[+2]_60 chr16:58549328-58549408 9.8e-05 15_[+2]_57 chr21:47609219-47609299 9.8e-05 49_[+2]_23 chrX:129216521-129216601 0.0001 1_[+2]_71 chr1:211752937-211753017 0.00014 [+2]_72 chr16:3202254-3202334 0.00014 22_[+2]_50 chr18:23807913-23807993 0.00014 49_[+2]_23 chr1:44457189-44457269 0.00016 17_[+2]_55 chr5:175815548-175815628 0.00016 17_[+2]_55 chr4:103266662-103266742 0.00018 1_[+2]_71 chr2:191746736-191746816 0.00018 55_[+2]_17 chr17:4458609-4458689 0.00026 26_[+2]_46 chr3:12909893-12909973 0.00026 50_[+2]_22 chr10:99161011-99161091 0.00026 31_[+2]_41 chr12:122461414-12246149 0.00026 11_[+2]_61 chr8:95907981-95908061 0.00026 40_[+2]_32 chr16:22960172-22960252 0.00028 55_[+2]_17 chr12:104682569-10468264 0.00032 19_[+2]_53 chr9:140444862-140444942 0.00035 17_[+2]_55 chr17:2305017-2305097 0.00039 1_[+2]_71 chr14:77279230-77279310 0.00043 51_[+2]_21 chr3:122512698-122512778 0.00046 43_[+2]_29 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif HAAACAAR MEME-2 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF HAAACAAR width=8 seqs=49 chr22:29949800-29949880 ( 38) AAAACAAA 1 chr12:50813523-50813603 ( 4) AAAACAAA 1 chr17:38255627-38255707 ( 52) AAAACAAA 1 chr17:44269101-44269181 ( 16) AAAACAAA 1 chr15:85143708-85143788 ( 8) AAAACAAA 1 chr7:155090786-155090866 ( 53) AAAACAAA 1 chr22:39541778-39541858 ( 39) TAAACAAG 1 chr19:1847775-1847855 ( 14) TAAACAAG 1 chr12:49463690-49463770 ( 18) AAAACAAG 1 chr11:77531990-77532070 ( 67) AAAACAAG 1 chr12:104354526-10435460 ( 62) TAAACACA 1 chr1:24120008-24120088 ( 65) TAAACACA 1 chr11:94226537-94226617 ( 6) TAAATAAA 1 chr5:90628226-90628306 ( 53) TAAACAAT 1 chr10:99094492-99094572 ( 17) TAAACAAT 1 chr17:58754771-58754851 ( 55) TAAACAGA 1 chr19:18350288-18350368 ( 30) AAAACAAT 1 chr16:70148043-70148123 ( 23) CAAACAAG 1 chr12:48152906-48152986 ( 70) CAAACAAG 1 chr11:9594378-9594458 ( 38) TAAACACG 1 chr4:90032286-90032366 ( 7) TAAACACG 1 chr12:120755569-12075564 ( 44) TAAATAAG 1 chr6:42016722-42016802 ( 24) TAAACAAC 1 chr3:186648864-186648944 ( 10) ACAACAAA 1 chr19:46270851-46270931 ( 11) ACAACAAA 1 chr17:37558909-37558989 ( 32) GAAACAAG 1 chr5:175963612-175963692 ( 59) ACAACAAA 1 chr1:3541337-3541417 ( 13) TAAACAGG 1 chr16:58549328-58549408 ( 16) AAAACAGG 1 chr21:47609219-47609299 ( 50) AAAAAAAA 1 chrX:129216521-129216601 ( 2) CAAACACA 1 chr1:211752937-211753017 ( 1) CAAACAGA 1 chr16:3202254-3202334 ( 23) TAAAAAAG 1 chr18:23807913-23807993 ( 50) CAAACAGA 1 chr1:44457189-44457269 ( 18) CAAACACG 1 chr5:175815548-175815628 ( 18) CAAACACG 1 chr4:103266662-103266742 ( 2) CAAATAAG 1 chr2:191746736-191746816 ( 56) GAAACAAT 1 chr17:4458609-4458689 ( 27) GAAACACG 1 chr3:12909893-12909973 ( 51) CAAACAGG 1 chr10:99161011-99161091 ( 32) GAAACACG 1 chr12:122461414-12246149 ( 12) TCAATAAA 1 chr8:95907981-95908061 ( 41) TAAACACC 1 chr16:22960172-22960252 ( 56) GCAACAAA 1 chr12:104682569-10468264 ( 20) TCAACAGA 1 chr9:140444862-140444942 ( 18) TAAACAGC 1 chr17:2305017-2305097 ( 2) ACAACACG 1 chr14:77279230-77279310 ( 52) ACAACAAC 1 chr3:122512698-122512778 ( 44) GAAATACA 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif HAAACAAR MEME-2 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 10.4541 E= 1.1e-010 85 -80 -138 102 221 -97 -1226 -1226 247 -1226 -1226 -1226 247 -1226 -1226 -1226 -214 142 -1226 -83 247 -1226 -1226 -1226 171 -38 -96 -1226 125 -197 36 -115 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif HAAACAAR MEME-2 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 49 E= 1.1e-010 0.326531 0.183673 0.122449 0.367347 0.836735 0.163265 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.040816 0.857143 0.000000 0.102041 1.000000 0.000000 0.000000 0.000000 0.591837 0.244898 0.163265 0.000000 0.428571 0.081633 0.408163 0.081633 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif HAAACAAR MEME-2 regular expression -------------------------------------------------------------------------------- [TA]AAACA[AC][AG] -------------------------------------------------------------------------------- Time 8.33 secs. ******************************************************************************** ******************************************************************************** MOTIF YTTGTTTW MEME-3 width = 8 sites = 35 llr = 306 E-value = 1.5e-008 ******************************************************************************** -------------------------------------------------------------------------------- Motif YTTGTTTW MEME-3 Description -------------------------------------------------------------------------------- Simplified A :1:::::5 pos.-specific C 3::::::1 probability G 2::9:121 matrix T 59a1a984 bits 2.5 * * 2.2 * * 2.0 ** ** 1.7 ** ** Relative 1.5 ** *** Entropy 1.2 ** *** (12.6 bits) 1.0 ****** 0.7 ******* 0.5 ******** 0.2 ******** 0.0 -------- Multilevel TTTGTTTA consensus C GT sequence G -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YTTGTTTW MEME-3 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr2:157189160-157189240 58 2.10e-06 CCAATGTGCC TTTGTTTA TGTGGCTTGC chr12:53765220-53765300 48 2.10e-06 CCCGGGCAGG TTTGTTTA CGAATCCGGC chr6:11112062-11112142 36 2.10e-06 cacatgtgca tttgttta ctgaagttgt chr8:124553528-124553608 28 2.10e-06 GCCACGTGGC TTTGTTTA TGGGCTCGGC chr10:50747182-50747262 5 4.21e-06 AGCG TTTGTTTT TAAGCACGGG chr3:122512698-122512778 21 4.21e-06 ACCACGCAGC TTTGTTTT GATACCCCGG chr1:25758746-25758826 32 7.89e-06 TGCACATGCT CTTGTTTA CAGATGTGGA chr11:66336092-66336172 16 7.89e-06 TGCGCGTTCT CTTGTTTA CAGGAGGCAC chr16:14728077-14728157 38 2.02e-05 TGCTGATGGG GTTGTTTT GTTTGTTCTT chr9:140429452-140429532 1 2.14e-05 . TTTTTTTT GGAACACTAG chr6:42016722-42016802 62 2.14e-05 tttctttttc tttttttt gagatggagt chr1:167191653-167191733 69 2.14e-05 CGATATGATT TTTTTTTT CCTT chr5:137690800-137690880 68 2.71e-05 TTCATTCAGT TATGTTTA AGATG chr12:132380705-13238078 20 2.71e-05 AGGCCGTGTG TTTGTTGA CATTGCTCCT chr16:31045663-31045743 69 2.71e-05 GCCAGAGTGG TTTGTTGA GGTG chr3:182817397-182817477 72 3.66e-05 GGGTGTGGCC TTTGTTTC T chr3:183353354-183353434 54 3.66e-05 ACATGTTTCC TTTGTTGT GAGCTGCGGC chr6:109704113-109704193 55 4.78e-05 AGGACCCCTT CTTTTTTT CTTGAAGATT chr8:81397755-81397835 40 4.78e-05 tgttcgacct tttattta aatttccatt chr1:6661285-6661365 27 6.16e-05 AACATGTGAC CATGTTTA CAGGCTCCGG chr12:107487495-10748757 11 6.16e-05 TGATCCCAAA CTTGTTGA CCCTCGTCCA chr4:186317807-186317887 38 6.16e-05 CGTGCCAGTG TTTGTGTA CGTGCGGCCG chrX:153991776-153991856 3 9.54e-05 GG GATGTTTA AGCTCTGCCA chr11:123940245-12394032 64 9.54e-05 tctaagggtg gatgttta cagctgaag chr16:89283045-89283125 31 9.54e-05 ctgggcacat cttgtttc ttaatcagcc chr8:26240466-26240546 18 9.54e-05 CGTCCGGTCG CTTGTTGT GTTGTCATCA chr6:5261357-5261437 72 9.54e-05 GGCGGAGACA TTTGTGTT T chr12:120763357-12076343 48 9.54e-05 TAGTTGCTGT GATGTTTA CTGTTGCTAC chr22:24181346-24181426 60 1.15e-04 GCACGTGGCG GTTGTTGT GGCTGCGGTG chr11:120894731-12089481 57 1.15e-04 GGGGTCACGT GTTGTTGT TGGGCCGGGA chr4:87952118-87952198 56 1.15e-04 ATTTGAGATC GTTGTTTC AGGCTGAGGA chr3:66271349-66271429 36 1.15e-04 TGCACGTGCA GTTGTTGT GGTTCTACGT chr20:44992642-44992722 24 1.45e-04 CTGACGTTTC CTTGTTTG CTCACGTGTT chr16:74402183-74402263 50 1.45e-04 GCCACGTGGG CTTGTTTG GGTCTCGCGA chr9:6007106-6007186 45 3.05e-04 TGAGTGTGTG TTTGTGTC AGTCTGTCAG -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YTTGTTTW MEME-3 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr2:157189160-157189240 2.1e-06 57_[+3]_15 chr12:53765220-53765300 2.1e-06 47_[+3]_25 chr6:11112062-11112142 2.1e-06 35_[+3]_37 chr8:124553528-124553608 2.1e-06 27_[+3]_45 chr10:50747182-50747262 4.2e-06 4_[+3]_68 chr3:122512698-122512778 4.2e-06 20_[+3]_52 chr1:25758746-25758826 7.9e-06 31_[+3]_41 chr11:66336092-66336172 7.9e-06 15_[+3]_57 chr16:14728077-14728157 2e-05 37_[+3]_35 chr9:140429452-140429532 2.1e-05 [+3]_72 chr6:42016722-42016802 2.1e-05 61_[+3]_11 chr1:167191653-167191733 2.1e-05 68_[+3]_4 chr5:137690800-137690880 2.7e-05 67_[+3]_5 chr12:132380705-13238078 2.7e-05 19_[+3]_53 chr16:31045663-31045743 2.7e-05 68_[+3]_4 chr3:182817397-182817477 3.7e-05 71_[+3]_1 chr3:183353354-183353434 3.7e-05 53_[+3]_19 chr6:109704113-109704193 4.8e-05 54_[+3]_18 chr8:81397755-81397835 4.8e-05 39_[+3]_33 chr1:6661285-6661365 6.2e-05 26_[+3]_46 chr12:107487495-10748757 6.2e-05 10_[+3]_62 chr4:186317807-186317887 6.2e-05 37_[+3]_35 chrX:153991776-153991856 9.5e-05 2_[+3]_70 chr11:123940245-12394032 9.5e-05 63_[+3]_9 chr16:89283045-89283125 9.5e-05 30_[+3]_42 chr8:26240466-26240546 9.5e-05 17_[+3]_55 chr6:5261357-5261437 9.5e-05 71_[+3]_1 chr12:120763357-12076343 9.5e-05 47_[+3]_25 chr22:24181346-24181426 0.00012 59_[+3]_13 chr11:120894731-12089481 0.00012 56_[+3]_16 chr4:87952118-87952198 0.00012 55_[+3]_17 chr3:66271349-66271429 0.00012 35_[+3]_37 chr20:44992642-44992722 0.00014 23_[+3]_49 chr16:74402183-74402263 0.00014 49_[+3]_23 chr9:6007106-6007186 0.0003 44_[+3]_28 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YTTGTTTW MEME-3 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF YTTGTTTW width=8 seqs=35 chr2:157189160-157189240 ( 58) TTTGTTTA 1 chr12:53765220-53765300 ( 48) TTTGTTTA 1 chr6:11112062-11112142 ( 36) TTTGTTTA 1 chr8:124553528-124553608 ( 28) TTTGTTTA 1 chr10:50747182-50747262 ( 5) TTTGTTTT 1 chr3:122512698-122512778 ( 21) TTTGTTTT 1 chr1:25758746-25758826 ( 32) CTTGTTTA 1 chr11:66336092-66336172 ( 16) CTTGTTTA 1 chr16:14728077-14728157 ( 38) GTTGTTTT 1 chr9:140429452-140429532 ( 1) TTTTTTTT 1 chr6:42016722-42016802 ( 62) TTTTTTTT 1 chr1:167191653-167191733 ( 69) TTTTTTTT 1 chr5:137690800-137690880 ( 68) TATGTTTA 1 chr12:132380705-13238078 ( 20) TTTGTTGA 1 chr16:31045663-31045743 ( 69) TTTGTTGA 1 chr3:182817397-182817477 ( 72) TTTGTTTC 1 chr3:183353354-183353434 ( 54) TTTGTTGT 1 chr6:109704113-109704193 ( 55) CTTTTTTT 1 chr8:81397755-81397835 ( 40) TTTATTTA 1 chr1:6661285-6661365 ( 27) CATGTTTA 1 chr12:107487495-10748757 ( 11) CTTGTTGA 1 chr4:186317807-186317887 ( 38) TTTGTGTA 1 chrX:153991776-153991856 ( 3) GATGTTTA 1 chr11:123940245-12394032 ( 64) GATGTTTA 1 chr16:89283045-89283125 ( 31) CTTGTTTC 1 chr8:26240466-26240546 ( 18) CTTGTTGT 1 chr6:5261357-5261437 ( 72) TTTGTGTT 1 chr12:120763357-12076343 ( 48) GATGTTTA 1 chr22:24181346-24181426 ( 60) GTTGTTGT 1 chr11:120894731-12089481 ( 57) GTTGTTGT 1 chr4:87952118-87952198 ( 56) GTTGTTTC 1 chr3:66271349-66271429 ( 36) GTTGTTGT 1 chr20:44992642-44992722 ( 24) CTTGTTTG 1 chr16:74402183-74402263 ( 50) CTTGTTTG 1 chr9:6007106-6007186 ( 45) TTTGTGTC 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YTTGTTTW MEME-3 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 10.8043 E= 1.5e-008 -1177 -31 -48 150 -34 -1177 -1177 224 -1177 -1177 -1177 246 -266 -1177 143 -67 -1177 -1177 -1177 246 -1177 -1177 -189 233 -1177 -1177 -48 209 134 -148 -248 103 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YTTGTTTW MEME-3 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 35 E= 1.5e-008 0.000000 0.257143 0.228571 0.514286 0.142857 0.000000 0.000000 0.857143 0.000000 0.000000 0.000000 1.000000 0.028571 0.000000 0.857143 0.114286 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.085714 0.914286 0.000000 0.000000 0.228571 0.771429 0.457143 0.114286 0.057143 0.371429 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YTTGTTTW MEME-3 regular expression -------------------------------------------------------------------------------- [TCG]TTGTT[TG][AT] -------------------------------------------------------------------------------- Time 11.73 secs. ******************************************************************************** ******************************************************************************** MOTIF CTTTAARR MEME-4 width = 8 sites = 10 llr = 105 E-value = 5.2e+003 ******************************************************************************** -------------------------------------------------------------------------------- Motif CTTTAARR MEME-4 Description -------------------------------------------------------------------------------- Simplified A 11::aa56 pos.-specific C 9::::::: probability G ::::::53 matrix T :9aa:::1 bits 2.5 **** 2.2 **** 2.0 ***** 1.7 ***** Relative 1.5 ***** Entropy 1.2 ****** (15.1 bits) 1.0 ******** 0.7 ******** 0.5 ******** 0.2 ******** 0.0 -------- Multilevel CTTTAAAA consensus GG sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTTTAARR MEME-4 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr16:4784752-4784832 55 2.06e-06 ACTTCCACAG CTTTAAAA TTTAAAAGCT chr2:68385006-68385086 44 5.70e-06 GCCGGCAGCG CTTTAAGA TTTCCGGGGA chr2:30369408-30369488 9 5.70e-06 GCCTTCGC CTTTAAGA AGCTGACTCA chr5:175963612-175963692 9 5.70e-06 CGCTGCGA CTTTAAGA GCCGAGGATC chr20:39657118-39657198 11 9.34e-06 CCGCCGCGGC CTTTAAAG GCCCACCACG chr9:73029013-73029093 63 1.05e-05 GAACACTGAC ATTTAAAA GGGTAACAGC chr17:4268536-4268616 25 1.26e-05 GTTCATTTCT CTTTAAAT CTGGCAGCAC chr12:131324045-13132412 63 1.90e-05 CGAACCTTCT CTTTAAGG GTCCACGCGC chr16:83986630-83986710 45 1.90e-05 AGCAGGGGCC CTTTAAGG CTGGCCATGA chr16:3202254-3202334 4 2.31e-05 CGT CATTAAAA TACAGATTTT -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTTTAARR MEME-4 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr16:4784752-4784832 2.1e-06 54_[+4]_18 chr2:68385006-68385086 5.7e-06 43_[+4]_29 chr2:30369408-30369488 5.7e-06 8_[+4]_64 chr5:175963612-175963692 5.7e-06 8_[+4]_64 chr20:39657118-39657198 9.3e-06 10_[+4]_62 chr9:73029013-73029093 1.1e-05 62_[+4]_10 chr17:4268536-4268616 1.3e-05 24_[+4]_48 chr12:131324045-13132412 1.9e-05 62_[+4]_10 chr16:83986630-83986710 1.9e-05 44_[+4]_28 chr16:3202254-3202334 2.3e-05 3_[+4]_69 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTTTAARR MEME-4 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF CTTTAARR width=8 seqs=10 chr16:4784752-4784832 ( 55) CTTTAAAA 1 chr2:68385006-68385086 ( 44) CTTTAAGA 1 chr2:30369408-30369488 ( 9) CTTTAAGA 1 chr5:175963612-175963692 ( 9) CTTTAAGA 1 chr20:39657118-39657198 ( 11) CTTTAAAG 1 chr9:73029013-73029093 ( 63) ATTTAAAA 1 chr17:4268536-4268616 ( 25) CTTTAAAT 1 chr12:131324045-13132412 ( 63) CTTTAAGG 1 chr16:83986630-83986710 ( 45) CTTTAAGG 1 chr16:3202254-3202334 ( 4) CATTAAAA 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTTTAARR MEME-4 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 12.3073 E= 5.2e+003 -85 149 -997 -997 -85 -997 -997 231 -997 -997 -997 246 -997 -997 -997 246 247 -997 -997 -997 247 -997 -997 -997 147 -997 65 -997 173 -997 -9 -86 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTTTAARR MEME-4 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 10 E= 5.2e+003 0.100000 0.900000 0.000000 0.000000 0.100000 0.000000 0.000000 0.900000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.500000 0.000000 0.500000 0.000000 0.600000 0.000000 0.300000 0.100000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTTTAARR MEME-4 regular expression -------------------------------------------------------------------------------- CTTTAA[AG][AG] -------------------------------------------------------------------------------- Time 15.09 secs. ******************************************************************************** ******************************************************************************** MOTIF TTTHCATT MEME-5 width = 8 sites = 9 llr = 92 E-value = 5.2e+004 ******************************************************************************** -------------------------------------------------------------------------------- Motif TTTHCATT MEME-5 Description -------------------------------------------------------------------------------- Simplified A :::4:9:1 pos.-specific C :::29:2: probability G :::::::: matrix T aaa31189 bits 2.5 *** 2.2 *** 2.0 *** * * 1.7 *** * * Relative 1.5 *** *** Entropy 1.2 *** **** (14.8 bits) 1.0 *** **** 0.7 ******** 0.5 ******** 0.2 ******** 0.0 -------- Multilevel TTTACATT consensus T C sequence C -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTTHCATT MEME-5 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr1:167191653-167191733 29 2.09e-06 GTGTTTATAT TTTACATT CGCCCCATGT chr5:137690800-137690880 56 4.19e-06 ATTGGGCAGA TTTTCATT CAGTTATGTT chr17:66453941-66454021 59 4.19e-06 CGTGGCGGTG TTTTCATT GCCGGAGCCG chr8:81397755-81397835 50 7.86e-06 tttatttaaa tttccatt tcatcacagc chr2:191746736-191746816 2 9.05e-06 C TTTATATT TCGGGAGTGG chr9:140429452-140429532 73 1.27e-05 agctgaaata tttacact chr2:239197523-239197603 48 2.18e-05 CGTCGCTCTT TTTACATA AGACGCACAT chr6:42016722-42016802 51 2.60e-05 AGCGACttct ttttcttt ttcttttttt chr16:4784752-4784832 40 3.45e-05 AGCGATGGGC TTTCCACT TCCACAGCTT -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTTHCATT MEME-5 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr1:167191653-167191733 2.1e-06 28_[+5]_44 chr5:137690800-137690880 4.2e-06 55_[+5]_17 chr17:66453941-66454021 4.2e-06 58_[+5]_14 chr8:81397755-81397835 7.9e-06 49_[+5]_23 chr2:191746736-191746816 9.1e-06 1_[+5]_71 chr9:140429452-140429532 1.3e-05 72_[+5] chr2:239197523-239197603 2.2e-05 47_[+5]_25 chr6:42016722-42016802 2.6e-05 50_[+5]_22 chr16:4784752-4784832 3.5e-05 39_[+5]_33 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTTHCATT MEME-5 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF TTTHCATT width=8 seqs=9 chr1:167191653-167191733 ( 29) TTTACATT 1 chr5:137690800-137690880 ( 56) TTTTCATT 1 chr17:66453941-66454021 ( 59) TTTTCATT 1 chr8:81397755-81397835 ( 50) TTTCCATT 1 chr2:191746736-191746816 ( 2) TTTATATT 1 chr9:140429452-140429532 ( 73) TTTACACT 1 chr2:239197523-239197603 ( 48) TTTACATA 1 chr6:42016722-42016802 ( 51) TTTTCTTT 1 chr16:4784752-4784832 ( 40) TTTCCACT 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTTHCATT MEME-5 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 12.3898 E= 5.2e+004 -982 -982 -982 246 -982 -982 -982 246 -982 -982 -982 246 130 -52 -982 88 -982 148 -982 -71 230 -982 -982 -71 -982 -52 -982 210 -70 -982 -982 229 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTTHCATT MEME-5 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 9 E= 5.2e+004 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.444444 0.222222 0.000000 0.333333 0.000000 0.888889 0.000000 0.111111 0.888889 0.000000 0.000000 0.111111 0.000000 0.222222 0.000000 0.777778 0.111111 0.000000 0.000000 0.888889 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTTHCATT MEME-5 regular expression -------------------------------------------------------------------------------- TTT[ATC]CA[TC]T -------------------------------------------------------------------------------- Time 18.42 secs. ******************************************************************************** ******************************************************************************** SUMMARY OF MOTIFS ******************************************************************************** -------------------------------------------------------------------------------- Combined block diagrams: non-overlapping sites with p-value < 0.0001 -------------------------------------------------------------------------------- SEQUENCE NAME COMBINED P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr19:30335300-30335380 3.02e-02 57_[+1(6.94e-05)]_15 chr1:167191653-167191733 1.19e-05 28_[+5(2.09e-06)]_30_[+3(2.14e-05)]_\ 6 chr12:4378612-4378692 1.00e+00 80 chr19:54666170-54666250 4.80e-01 80 chr4:90032286-90032366 3.39e-03 6_[+2(5.18e-05)]_2_[+1(6.94e-05)]_\ 56 chr8:95907981-95908061 6.80e-02 80 chr9:140444862-140444942 7.78e-03 80 chrX:106920099-106920179 3.01e-01 80 chr11:66336092-66336172 5.57e-04 15_[+3(7.89e-06)]_57 chr9:35116316-35116396 1.03e-01 55_[+1(6.94e-05)]_17 chr12:48152906-48152986 4.92e-03 46_[+1(3.47e-05)]_15_[+2(4.19e-05)]_\ 3 chr16:70148043-70148123 7.40e-03 22_[+2(4.19e-05)]_1_[+1(3.47e-05)]_\ 41 chr21:47609219-47609299 6.07e-03 20_[+1(3.47e-05)]_20_[+2(9.78e-05)]_\ 24 chr8:124553528-124553608 7.55e-05 18_[+1(3.47e-05)]_1_[+3(2.10e-06)]_\ 9_[+3(1.53e-05)]_28 chr22:41777511-41777591 9.93e-01 80 chr17:49336702-49336782 3.00e-03 27_[+1(6.94e-05)]_45 chr19:50037104-50037184 4.82e-01 80 chr2:11919416-11919496 9.93e-02 32_[+1(3.47e-05)]_40 chr19:55691518-55691598 4.53e-01 80 chr11:45868783-45868863 5.19e-01 80 chr17:2303037-2303117 6.14e-01 80 chr4:186317807-186317887 1.09e-02 24_[+1(6.94e-05)]_5_[+3(6.16e-05)]_\ 35 chr16:14728077-14728157 2.44e-04 37_[+3(2.02e-05)]_35 chr15:68522409-68522489 1.24e-01 80 chr16:74402183-74402263 1.97e-02 40_[+1(3.47e-05)]_32 chr15:85524117-85524197 1.32e-01 80 chr8:144025193-144025273 7.45e-03 53_[+1(6.94e-05)]_19 chr12:56513308-56513388 2.19e-01 80 chr11:9594378-9594458 9.83e-04 16_[+1(6.94e-05)]_13_[+2(5.18e-05)]_\ 35 chr9:132020876-132020956 1.11e-01 80 chr17:7184770-7184850 5.54e-04 80 chr5:175963612-175963692 1.59e-04 8_[+4(5.70e-06)]_42_[+2(7.93e-05)]_\ 14 chr16:56966970-56967050 1.25e-01 80 chr10:103893360-10389344 1.28e-01 39_[+1(3.47e-05)]_33 chr10:104474508-10447458 1.57e-01 60_[+1(3.47e-05)]_12 chr10:104677816-10467789 6.15e-02 80 chr2:239197523-239197603 8.33e-04 47_[+5(2.18e-05)]_25 chr19:55768869-55768949 1.17e-02 80 chr17:7747483-7747563 9.95e-01 80 chr16:4784752-4784832 6.55e-04 39_[+5(3.45e-05)]_7_[+4(2.06e-06)]_\ 18 chr17:37558909-37558989 1.62e-01 31_[+2(7.93e-05)]_41 chr12:120763357-12076343 5.53e-04 47_[+3(9.54e-05)]_25 chr18:23807913-23807993 2.53e-04 80 chr3:49966997-49967077 1.26e-02 19_[+1(3.47e-05)]_53 chr7:155090786-155090866 3.59e-03 52_[+2(4.07e-06)]_20 chr2:30369408-30369488 5.54e-04 8_[+4(5.70e-06)]_64 chr19:18547744-18547824 8.22e-01 80 chr19:14115774-14115854 3.21e-03 80 chr15:85143708-85143788 6.17e-04 7_[+2(4.07e-06)]_65 chr1:156251164-156251244 2.53e-01 80 chr19:46270851-46270931 1.95e-02 10_[+2(7.93e-05)]_62 chr20:39657118-39657198 1.59e-03 10_[+4(9.34e-06)]_5_[+1(3.47e-05)]_\ 49 chr3:66271349-66271429 3.35e-03 80 chr8:81397755-81397835 1.09e-07 49_[+5(7.86e-06)]_23 chr12:107487495-10748757 1.55e-02 10_[+3(6.16e-05)]_62 chr17:42404342-42404422 1.53e-01 80 chr21:33765248-33765328 3.02e-01 80 chr15:41407817-41407897 7.77e-02 48_[+1(6.94e-05)]_24 chr1:24120008-24120088 4.82e-04 36_[+1(3.47e-05)]_20_[+2(1.84e-05)]_\ 8 chr12:26267443-26267523 5.52e-01 80 chr17:5323318-5323398 1.05e-01 68_[+1(3.47e-05)]_4 chr17:44269101-44269181 3.01e-03 1_[+2(1.84e-05)]_6_[+2(4.07e-06)]_4_\ [+2(2.32e-05)]_45 chr3:183353354-183353434 1.38e-03 53_[+3(3.66e-05)]_19 chr16:30418599-30418679 2.81e-01 80 chr17:2303883-2303963 1.50e-02 49_[+1(6.94e-05)]_23 chr19:1864267-1864347 9.81e-01 80 chr1:6661285-6661365 6.03e-04 26_[+3(6.16e-05)]_46 chr4:57302508-57302588 1.75e-01 47_[+1(6.94e-05)]_25 chr6:11112062-11112142 4.99e-04 35_[+3(2.10e-06)]_37 chr5:139927199-139927279 4.27e-02 80 chr19:17580250-17580330 4.69e-02 80 chr3:167814046-167814126 4.28e-02 80 chr16:3202254-3202334 5.14e-06 3_[+4(2.31e-05)]_8_[+4(7.61e-05)]_\ 53 chr17:75316972-75317052 9.95e-03 80 chr3:67048544-67048624 8.46e-02 80 chr10:104001484-10400156 2.42e-01 19_[+1(3.47e-05)]_53 chr3:186648864-186648944 3.04e-03 9_[+2(7.93e-05)]_1_[+1(6.94e-05)]_\ 54 chr12:122461414-12246149 6.67e-03 21_[+1(6.94e-05)]_51 chr17:25853698-25853778 5.60e-02 80 chr16:31045663-31045743 1.04e-01 68_[+3(2.71e-05)]_4 chr17:4268536-4268616 3.73e-04 24_[+4(1.26e-05)]_48 chr19:18452167-18452247 2.08e-02 51_[+1(3.47e-05)]_21 chr4:52710951-52711031 1.83e-01 80 chr17:2305017-2305097 7.40e-03 80 chr2:232328534-232328614 3.27e-01 80 chr4:87952118-87952198 1.09e-04 31_[+1(6.94e-05)]_41 chr11:3663824-3663904 2.01e-01 14_[+1(6.94e-05)]_58 chr2:75062121-75062201 3.79e-01 80 chr12:53765220-53765300 4.28e-04 47_[+3(2.10e-06)]_25 chr10:11916876-11916956 2.02e-02 42_[+1(3.47e-05)]_30 chr9:127963007-127963087 1.11e-02 56_[+1(3.47e-05)]_16 chr16:29605738-29605818 3.33e-03 12_[+1(3.47e-05)]_60 chr19:49655096-49655176 2.85e-01 22_[+1(6.94e-05)]_50 chr19:1847775-1847855 6.63e-03 13_[+2(7.67e-06)]_59 chr19:30433691-30433771 1.63e-02 80 chr20:30467594-30467674 5.35e-01 80 chr12:132380705-13238078 1.21e-02 19_[+3(2.71e-05)]_53 chr19:47733585-47733665 6.79e-01 80 chr8:145800926-145801006 5.66e-03 80 chr17:66453941-66454021 2.47e-04 45_[+1(3.47e-05)]_5_[+5(4.19e-06)]_\ 14 chr19:1672499-1672579 2.44e-01 22_[+1(6.94e-05)]_50 chr6:42016722-42016802 2.44e-07 4_[+1(6.94e-05)]_11_[+2(7.93e-05)]_\ 19_[+5(2.60e-05)]_3_[+3(2.14e-05)]_11 chr11:120894731-12089481 1.78e-02 80 chr19:45909116-45909196 1.14e-02 25_[+1(6.94e-05)]_47 chr1:42800131-42800211 3.62e-01 80 chr12:110151420-11015150 1.75e-01 80 chr16:88519030-88519110 4.68e-02 80 chr2:85766880-85766960 8.42e-02 80 chr11:94226537-94226617 1.94e-05 9_[+2(2.04e-06)]_63 chr9:140429452-140429532 2.18e-06 [+3(2.14e-05)]_39_[+1(3.47e-05)]_17_\ [+5(1.27e-05)] chr12:109535789-10953586 9.99e-01 80 chr3:38495175-38495255 4.62e-01 80 chr9:6007106-6007186 5.63e-02 80 chr2:113403223-113403303 9.71e-01 80 chr1:12203863-12203943 3.79e-03 38_[+1(6.94e-05)]_34 chr1:110162327-110162407 5.98e-02 53_[+1(3.47e-05)]_19 chr17:8055855-8055935 3.71e-02 80 chr19:18350288-18350368 3.13e-03 29_[+2(4.19e-05)]_5_[+1(6.94e-05)]_\ 30 chr10:99094492-99094572 1.49e-02 16_[+2(3.00e-05)]_56 chr20:44992642-44992722 1.06e-02 80 chr4:2264036-2264116 1.31e-02 80 chr17:34890805-34890885 8.02e-02 80 chr17:33307430-33307510 1.08e-01 27_[+1(3.47e-05)]_45 chr11:65624483-65624563 6.14e-01 80 chr20:305106-305186 4.42e-01 80 chr2:191746736-191746816 2.45e-06 1_[+5(9.05e-06)]_71 chr5:176739254-176739334 3.52e-01 80 chr11:118851021-11885110 2.06e-02 4_[+1(3.47e-05)]_8_[+1(6.94e-05)]_\ 52 chr10:120924970-12092505 8.08e-01 80 chr12:104354526-10435460 8.31e-04 61_[+2(1.84e-05)]_11 chr7:65580511-65580591 1.45e-03 67_[+1(3.47e-05)]_5 chr6:5261357-5261437 5.46e-02 71_[+3(9.54e-05)]_1 chr17:71088795-71088875 3.70e-01 80 chr17:36831359-36831439 4.87e-01 80 chr4:109087760-109087840 5.62e-03 34_[+5(5.57e-05)]_38 chr1:44445511-44445591 1.76e-01 80 chr11:77531990-77532070 4.91e-04 66_[+2(1.12e-05)]_6 chr11:12131916-12131996 9.98e-01 80 chr7:100450152-100450232 1.95e-01 80 chr16:22960172-22960252 6.56e-03 40_[+1(3.47e-05)]_32 chr1:25758746-25758826 4.86e-05 31_[+3(7.89e-06)]_18_[+5(9.04e-05)]_\ 15 chr17:4635124-4635204 8.99e-02 80 chr10:102747302-10274738 5.05e-01 80 chr3:122512698-122512778 7.68e-06 20_[+3(4.21e-06)]_52 chr8:99129449-99129529 5.76e-02 42_[+1(3.47e-05)]_30 chr16:27246710-27246790 2.23e-02 60_[+1(3.47e-05)]_12 chr19:2977363-2977443 2.43e-01 57_[+1(6.94e-05)]_15 chr8:26240466-26240546 9.72e-03 17_[+3(9.54e-05)]_55 chr19:2346177-2346257 1.23e-01 53_[+1(3.47e-05)]_19 chr1:155243341-155243421 9.98e-02 19_[+1(6.94e-05)]_53 chr19:2151825-2151905 7.61e-02 64_[+1(3.47e-05)]_8 chr19:1045089-1045169 8.83e-01 80 chr16:83986630-83986710 1.08e-01 44_[+4(1.90e-05)]_28 chr22:31686769-31686849 4.89e-01 80 chr11:107729295-10772937 2.26e-01 19_[+1(6.94e-05)]_53 chr12:62654825-62654905 5.91e-03 67_[+1(3.47e-05)]_5 chr4:57301611-57301691 1.65e-01 80 chr8:109455753-109455833 6.19e-01 80 chr11:537305-537385 1.59e-01 60_[+1(3.47e-05)]_12 chr16:58549328-58549408 1.05e-02 15_[+2(9.78e-05)]_2_[+1(3.47e-05)]_\ 47 chr16:75267965-75268045 1.16e-01 80 chr17:38269599-38269679 7.86e-03 66_[+1(3.47e-05)]_6 chr5:154062178-154062258 1.22e-01 80 chr17:38255627-38255707 4.17e-04 51_[+2(4.07e-06)]_21 chr10:99161011-99161091 2.07e-03 47_[+1(3.47e-05)]_25 chr9:73029013-73029093 3.54e-03 62_[+4(1.05e-05)]_10 chr17:17109832-17109912 2.75e-01 64_[+1(6.94e-05)]_8 chr4:89514398-89514478 7.66e-01 80 chr16:89283045-89283125 3.50e-03 30_[+3(9.54e-05)]_42 chr11:119252508-11925258 1.74e-02 23_[+1(3.47e-05)]_49 chr12:50813523-50813603 4.01e-04 3_[+2(4.07e-06)]_10_[+1(3.47e-05)]_\ 51 chr3:183967325-183967405 5.62e-03 43_[+3(9.54e-05)]_29 chr12:123848118-12384819 5.81e-03 80 chr16:89766698-89766778 1.14e-01 40_[+1(6.94e-05)]_32 chr12:113659616-11365969 3.48e-01 80 chr20:42839576-42839656 2.88e-02 80 chr11:123940245-12394032 2.07e-02 63_[+3(9.54e-05)]_9 chr4:110736922-110737002 3.73e-02 80 chr9:140563962-140564042 3.38e-01 80 chr1:211752937-211753017 7.36e-03 29_[+1(3.47e-05)]_43 chr17:53315698-53315778 4.19e-01 80 chr19:5341040-5341120 4.04e-01 80 chr17:58754771-58754851 3.23e-03 10_[+1(6.94e-05)]_36_[+2(4.19e-05)]_\ 18 chr1:33501781-33501861 3.17e-02 80 chr3:12909893-12909973 2.98e-01 80 chr12:49463690-49463770 4.98e-03 17_[+2(1.12e-05)]_55 chr16:88877868-88877948 1.85e-01 25_[+1(6.94e-05)]_47 chr19:41903292-41903372 1.44e-01 80 chr10:75911098-75911178 6.39e-02 58_[+1(3.47e-05)]_14 chr19:4327290-4327370 5.66e-01 80 chr2:68385006-68385086 4.62e-04 43_[+4(5.70e-06)]_29 chr22:39541778-39541858 1.16e-02 38_[+2(7.67e-06)]_34 chr5:78642360-78642440 1.62e-01 80 chr17:4458609-4458689 2.14e-02 80 chr5:90628226-90628306 5.26e-05 37_[+1(3.47e-05)]_7_[+2(3.00e-05)]_\ 20 chr19:13096198-13096278 5.55e-02 44_[+1(3.47e-05)]_28 chr19:10400007-10400087 4.23e-02 80 chr8:11660056-11660136 9.27e-01 80 chr3:69788420-69788500 1.65e-01 80 chr1:31654643-31654723 8.46e-02 80 chr6:109704113-109704193 1.07e-03 54_[+3(4.78e-05)]_18 chr12:120755569-12075564 1.08e-04 43_[+2(6.38e-05)]_1_[+1(3.47e-05)]_\ 20 chr19:7570833-7570913 4.67e-02 45_[+1(6.94e-05)]_27 chr7:30323892-30323972 1.39e-01 35_[+1(6.94e-05)]_37 chr22:24181346-24181426 3.29e-02 80 chr16:79867620-79867700 6.08e-03 80 chrX:129216521-129216601 2.38e-03 21_[+1(6.94e-05)]_51 chr4:17579035-17579115 6.79e-02 9_[+1(6.94e-05)]_63 chr12:131324045-13132412 1.16e-03 62_[+4(1.90e-05)]_10 chr5:170815538-170815618 1.10e-01 49_[+1(3.47e-05)]_23 chr16:128043-128123 1.00e+00 80 chr12:104682569-10468264 1.19e-01 80 chr4:83351705-83351785 6.12e-02 30_[+1(3.47e-05)]_42 chr15:75497201-75497281 5.58e-01 80 chr22:41763217-41763297 8.05e-02 45_[+1(6.94e-05)]_27 chr3:50563567-50563647 7.17e-02 80 chr14:77279230-77279310 6.20e-04 25_[+1(3.47e-05)]_47 chr9:140565420-140565500 1.55e-02 80 chrX:153991776-153991856 1.01e-03 2_[+3(9.54e-05)]_13_[+1(3.47e-05)]_\ 49 chr12:8380264-8380344 2.13e-03 11_[+1(3.47e-05)]_33_[+5(6.76e-05)]_\ 20 chr10:50747182-50747262 1.32e-06 4_[+3(4.21e-06)]_15_[+1(3.47e-05)]_\ 26_[+5(7.34e-05)]_11 chr19:4968834-4968914 1.31e-01 80 chr2:88991322-88991402 5.30e-02 10_[+1(6.94e-05)]_62 chr5:175815548-175815628 2.35e-02 80 chr10:26986846-26986926 5.56e-01 80 chr1:6454167-6454247 1.52e-02 80 chr16:69166527-69166607 3.72e-01 80 chr5:137690800-137690880 1.66e-05 55_[+5(4.19e-06)]_4_[+3(2.71e-05)]_\ 5 chr15:98503705-98503785 8.96e-02 80 chr19:50180739-50180819 1.19e-01 58_[+1(3.47e-05)]_14 chr22:29949800-29949880 6.37e-05 37_[+2(4.07e-06)]_35 chr4:103266662-103266742 2.24e-03 80 chr11:114310015-11431009 1.23e-03 5_[+2(6.38e-05)]_67 chr6:97345678-97345758 1.05e-01 80 chr4:4291771-4291851 1.77e-01 80 chr21:46961665-46961745 1.38e-01 80 chr20:20033178-20033258 9.62e-01 80 chr8:103425154-103425234 3.14e-01 80 chr1:159750735-159750815 1.26e-01 19_[+1(3.47e-05)]_53 chr11:71159706-71159786 1.53e-01 14_[+1(3.47e-05)]_58 chr7:77485128-77485208 2.01e-03 24_[+1(3.47e-05)]_48 chr5:172410732-172410812 7.41e-02 80 chr19:36605861-36605941 1.36e-01 80 chr1:227128125-227128205 1.94e-01 80 chr1:3541337-3541417 5.39e-03 12_[+2(9.04e-05)]_60 chr1:31628299-31628379 2.34e-01 46_[+1(3.47e-05)]_26 chr1:44457189-44457269 5.42e-02 80 chr2:157189160-157189240 3.54e-03 57_[+3(2.10e-06)]_15 chr22:40742713-40742793 4.39e-01 80 chr3:182817397-182817477 1.07e-03 47_[+1(6.94e-05)]_16_[+3(3.66e-05)]_\ 1 -------------------------------------------------------------------------------- ******************************************************************************** ******************************************************************************** Stopped because requested number of motifs (5) found. ******************************************************************************** CPU: c22n07.farnam.hpc.yale.internal ********************************************************************************