******************************************************************************** MEME - Motif discovery tool ******************************************************************************** MEME version 5.3.3 (Release date: Sun Feb 7 15:39:52 2021 -0800) For further information on how to interpret these results please access https://meme-suite.org/meme. To get a copy of the MEME Suite software please access https://meme-suite.org. ******************************************************************************** ******************************************************************************** REFERENCE ******************************************************************************** If you use this program in your research, please cite: Timothy L. Bailey and Charles Elkan, "Fitting a mixture model by expectation maximization to discover motifs in biopolymers", Proceedings of the Second International Conference on Intelligent Systems for Molecular Biology, pp. 28-36, AAAI Press, Menlo Park, California, 1994. ******************************************************************************** ******************************************************************************** TRAINING SET ******************************************************************************** PRIMARY SEQUENCES= ../result/final_prediction/K562/fasta/RankLinear0.6_40/MCM7.fasta CONTROL SEQUENCES= --none-- ALPHABET= ACGT Sequence name Weight Length Sequence name Weight Length ------------- ------ ------ ------------- ------ ------ chr22:20948959-20949039 1.0000 80 chr22:23439522-23439602 1.0000 80 chr22:23165343-23165423 1.0000 80 chr22:17197483-17197563 1.0000 80 chr22:23100767-23100847 1.0000 80 chr22:19612681-19612761 1.0000 80 chr16:85052817-85052897 1.0000 80 chr21:33769146-33769226 1.0000 80 chr22:22732891-22732971 1.0000 80 chr1:172584831-172584911 1.0000 80 chr7:111208624-111208704 1.0000 80 chr2:169134657-169134737 1.0000 80 chr22:23159043-23159123 1.0000 80 chr13:90503975-90504055 1.0000 80 chr19:54929563-54929643 1.0000 80 chr13:92270043-92270123 1.0000 80 chr5:110103997-110104077 1.0000 80 chr7:137690841-137690921 1.0000 80 chr22:22077702-22077782 1.0000 80 chr10:47015549-47015629 1.0000 80 chr21:46968182-46968262 1.0000 80 chr6:6721141-6721221 1.0000 80 chr13:92231711-92231791 1.0000 80 chr2:174859491-174859571 1.0000 80 chr8:12404300-12404380 1.0000 80 chr1:29464626-29464706 1.0000 80 chr22:20175758-20175838 1.0000 80 chr10:59946741-59946821 1.0000 80 chr22:21053237-21053317 1.0000 80 chr9:125101388-125101468 1.0000 80 chr7:127754091-127754171 1.0000 80 chr6:140152670-140152750 1.0000 80 chr13:92309314-92309394 1.0000 80 chr19:8197792-8197872 1.0000 80 chr13:90661321-90661401 1.0000 80 chr3:46041236-46041316 1.0000 80 chr22:23502597-23502677 1.0000 80 chr17:56763701-56763781 1.0000 80 chr22:22761549-22761629 1.0000 80 chr13:81462934-81463014 1.0000 80 chr22:22506189-22506269 1.0000 80 chr7:139889609-139889689 1.0000 80 chr7:138995401-138995481 1.0000 80 chr7:151080882-151080962 1.0000 80 chr21:33947463-33947543 1.0000 80 chr22:20787297-20787377 1.0000 80 chr6:130504905-130504985 1.0000 80 chr2:157267821-157267901 1.0000 80 chr10:76842639-76842719 1.0000 80 chr17:28428985-28429065 1.0000 80 chr22:23004569-23004649 1.0000 80 chr2:25155761-25155841 1.0000 80 chr6:38684164-38684244 1.0000 80 chr2:91764658-91764738 1.0000 80 chr7:73858766-73858846 1.0000 80 chr22:23423970-23424050 1.0000 80 chr22:21330736-21330816 1.0000 80 chr22:23287573-23287653 1.0000 80 chr7:143098688-143098768 1.0000 80 chr1:17024028-17024108 1.0000 80 chr22:21018983-21019063 1.0000 80 chr22:22751695-22751775 1.0000 80 chr1:40600459-40600539 1.0000 80 chr12:71671427-71671507 1.0000 80 chr22:22424989-22425069 1.0000 80 chr22:22410142-22410222 1.0000 80 chr22:23165927-23166007 1.0000 80 chr1:192252891-192252971 1.0000 80 chr13:92382259-92382339 1.0000 80 chr6:31682144-31682224 1.0000 80 chr2:91770643-91770723 1.0000 80 chr22:23135412-23135492 1.0000 80 chr22:23118883-23118963 1.0000 80 chr22:23454818-23454898 1.0000 80 chr7:138137973-138138053 1.0000 80 chr1:162460781-162460861 1.0000 80 chr13:91796467-91796547 1.0000 80 chr22:23141231-23141311 1.0000 80 chr12:101917302-10191738 1.0000 80 chr1:145080541-145080621 1.0000 80 chr1:31107202-31107282 1.0000 80 chrX:9379883-9379963 1.0000 80 chr17:28799748-28799828 1.0000 80 chr22:22390362-22390442 1.0000 80 chr22:22362796-22362876 1.0000 80 chr22:21329431-21329511 1.0000 80 chr22:22382974-22383054 1.0000 80 chr22:23214811-23214891 1.0000 80 chr1:180569496-180569576 1.0000 80 chr13:92450109-92450189 1.0000 80 chr10:47084373-47084453 1.0000 80 chr7:158517360-158517440 1.0000 80 chr21:46967451-46967531 1.0000 80 chr5:12113-12193 1.0000 80 chr6:36279100-36279180 1.0000 80 chr12:66658469-66658549 1.0000 80 chr6:39828348-39828428 1.0000 80 chr22:22520868-22520948 1.0000 80 chr1:32202868-32202948 1.0000 80 chr22:22693329-22693409 1.0000 80 chr17:27042735-27042815 1.0000 80 chr3:150789702-150789782 1.0000 80 chr19:54387130-54387210 1.0000 80 chr1:48080800-48080880 1.0000 80 chr18:3294508-3294588 1.0000 80 chr1:101212056-101212136 1.0000 80 chr22:23381775-23381855 1.0000 80 chr2:169841634-169841714 1.0000 80 chr22:23451098-23451178 1.0000 80 chr1:4188372-4188452 1.0000 80 chr22:22471940-22472020 1.0000 80 chr22:22564256-22564336 1.0000 80 chr18:9326197-9326277 1.0000 80 chr22:20723811-20723891 1.0000 80 chr1:17040147-17040227 1.0000 80 chr3:14376240-14376320 1.0000 80 chr15:45081092-45081172 1.0000 80 chr22:23280898-23280978 1.0000 80 chr19:16217266-16217346 1.0000 80 chr13:91946847-91946927 1.0000 80 chr12:62821411-62821491 1.0000 80 chr6:112430584-112430664 1.0000 80 chr10:46955145-46955225 1.0000 80 chr13:91717001-91717081 1.0000 80 chr1:20255665-20255745 1.0000 80 chr22:22426591-22426671 1.0000 80 chr6:29527886-29527966 1.0000 80 chr6:27590800-27590880 1.0000 80 chr7:155389832-155389912 1.0000 80 chr8:2272284-2272364 1.0000 80 chr7:150846871-150846951 1.0000 80 chr22:22434558-22434638 1.0000 80 chr11:34453438-34453518 1.0000 80 chr22:23329940-23330020 1.0000 80 chr22:19138611-19138691 1.0000 80 chr2:149365343-149365423 1.0000 80 chr13:91039741-91039821 1.0000 80 chr3:170402799-170402879 1.0000 80 chr22:23158413-23158493 1.0000 80 chr5:71186298-71186378 1.0000 80 chr22:20282423-20282503 1.0000 80 chr13:91456631-91456711 1.0000 80 chr7:121063038-121063118 1.0000 80 chr15:39803446-39803526 1.0000 80 chr22:23327020-23327100 1.0000 80 chr22:18977937-18978017 1.0000 80 chr22:23380507-23380587 1.0000 80 chr22:23002482-23002562 1.0000 80 chr1:37228236-37228316 1.0000 80 chr22:23235421-23235501 1.0000 80 chr1:197835621-197835701 1.0000 80 chr7:112768562-112768642 1.0000 80 chr22:23140251-23140331 1.0000 80 chr6:11398123-11398203 1.0000 80 chr22:20294231-20294311 1.0000 80 chr16:24541168-24541248 1.0000 80 chr7:92179406-92179486 1.0000 80 chr21:44368757-44368837 1.0000 80 chr12:131733822-13173390 1.0000 80 chr13:81310125-81310205 1.0000 80 chr22:23361658-23361738 1.0000 80 chr7:130822322-130822402 1.0000 80 chr1:227746872-227746952 1.0000 80 chr3:41287641-41287721 1.0000 80 chr10:47133578-47133658 1.0000 80 chr8:103032982-103033062 1.0000 80 chr21:46965536-46965616 1.0000 80 chr7:111361125-111361205 1.0000 80 chr1:1520586-1520666 1.0000 80 chr22:22504504-22504584 1.0000 80 chr1:110284530-110284610 1.0000 80 chr13:92401126-92401206 1.0000 80 chr22:21387233-21387313 1.0000 80 chr6:111192713-111192793 1.0000 80 chr7:152434122-152434202 1.0000 80 chr17:63123766-63123846 1.0000 80 chr7:143046983-143047063 1.0000 80 chr1:225705518-225705598 1.0000 80 chr22:22097940-22098020 1.0000 80 chr1:116621631-116621711 1.0000 80 chr19:51311654-51311734 1.0000 80 chr15:20501658-20501738 1.0000 80 chr6:39268581-39268661 1.0000 80 chr1:3676822-3676902 1.0000 80 chr11:56981520-56981600 1.0000 80 chr2:91778050-91778130 1.0000 80 chr22:21419607-21419687 1.0000 80 chr2:149553883-149553963 1.0000 80 chr13:91768175-91768255 1.0000 80 chr22:23017208-23017288 1.0000 80 chr13:91489048-91489128 1.0000 80 chr22:23261312-23261392 1.0000 80 chr13:90662359-90662439 1.0000 80 chr21:43812448-43812528 1.0000 80 chr2:55925975-55926055 1.0000 80 chr7:150059078-150059158 1.0000 80 chr22:19757333-19757413 1.0000 80 chr22:23242764-23242844 1.0000 80 chr13:90946173-90946253 1.0000 80 chr22:23081571-23081651 1.0000 80 chr22:23372984-23373064 1.0000 80 chr15:20864827-20864907 1.0000 80 chr17:74006031-74006111 1.0000 80 chr17:44328239-44328319 1.0000 80 chr16:31109757-31109837 1.0000 80 chr22:17008725-17008805 1.0000 80 chr1:223413749-223413829 1.0000 80 chr10:47014275-47014355 1.0000 80 chr22:23463992-23464072 1.0000 80 chr16:33418464-33418544 1.0000 80 chr13:81457347-81457427 1.0000 80 chr6:170725382-170725462 1.0000 80 chr2:100116290-100116370 1.0000 80 chr13:91561196-91561276 1.0000 80 chr1:22141659-22141739 1.0000 80 chr22:22365170-22365250 1.0000 80 chr12:94930056-94930136 1.0000 80 chr22:23468704-23468784 1.0000 80 chr11:108508187-10850826 1.0000 80 chr2:183940950-183941030 1.0000 80 chr15:79329093-79329173 1.0000 80 chr7:100643412-100643492 1.0000 80 chr22:23378980-23379060 1.0000 80 chr6:7322162-7322242 1.0000 80 chr7:138711875-138711955 1.0000 80 chr22:21248925-21249005 1.0000 80 chr7:116073060-116073140 1.0000 80 chr13:90655944-90656024 1.0000 80 chr22:20955517-20955597 1.0000 80 chr7:117612058-117612138 1.0000 80 chr13:81256343-81256423 1.0000 80 chr22:22756009-22756089 1.0000 80 chr22:23469436-23469516 1.0000 80 chr1:234455956-234456036 1.0000 80 chr22:23418194-23418274 1.0000 80 chr7:140116339-140116419 1.0000 80 chr22:23271913-23271993 1.0000 80 chr22:22569614-22569694 1.0000 80 chr1:22372037-22372117 1.0000 80 chr12:93859051-93859131 1.0000 80 chr1:206285175-206285255 1.0000 80 chr9:140811202-140811282 1.0000 80 chr7:139915101-139915181 1.0000 80 chr1:12606621-12606701 1.0000 80 chr22:23465394-23465474 1.0000 80 chr6:35756501-35756581 1.0000 80 chr9:95566952-95567032 1.0000 80 chr22:23336245-23336325 1.0000 80 chr22:21913507-21913587 1.0000 80 chr6:6700019-6700099 1.0000 80 ******************************************************************************** ******************************************************************************** COMMAND LINE SUMMARY ******************************************************************************** This information can also be useful in the event you wish to report a problem with the MEME software. command: meme -oc ../result/final_prediction/K562/inference_raw/MEME/RankLinear0.6_40_MCM7/ -dna -nmotifs 5 -w 8 -maxsize 250000 -nostatus ../result/final_prediction/K562/fasta/RankLinear0.6_40/MCM7.fasta model: mod= zoops nmotifs= 5 evt= inf objective function: em= E-value of product of p-values starts= E-value of product of p-values strands: + width: minw= 8 maxw= 8 nsites: minsites= 2 maxsites= 250 wnsites= 0.8 theta: spmap= uni spfuzz= 0.5 em: prior= dirichlet b= 0.01 maxiter= 50 distance= 1e-05 trim: wg= 11 ws= 1 endgaps= yes data: n= 20000 N= 250 sample: seed= 0 hsfrac= 0 searchsize= 20000 norand= no csites= 1000 Letter frequencies in dataset: A 0.257 C 0.241 G 0.251 T 0.251 Background letter frequencies (from file dataset with add-one prior applied): A 0.257 C 0.241 G 0.251 T 0.251 Background model order: 0 ******************************************************************************** ******************************************************************************** MOTIF CTCTKCCT MEME-1 width = 8 sites = 42 llr = 364 E-value = 2.8e-015 ******************************************************************************** -------------------------------------------------------------------------------- Motif CTCTKCCT MEME-1 Description -------------------------------------------------------------------------------- Simplified A :::2:::2 pos.-specific C a:a:17a: probability G ::::6::: matrix T :a:843:8 bits 2.1 *** * 1.8 *** * 1.6 *** * 1.4 *** * Relative 1.2 **** *** Entropy 1.0 **** *** (12.5 bits) 0.8 ******** 0.6 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel CTCTGCCT consensus ATT A sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTCTKCCT MEME-1 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr13:81256343-81256423 18 1.34e-05 gtttttctat ctctgcct gactgcttga chr7:117612058-117612138 47 1.34e-05 tctctgcaac ctctgcct tccaggttca chr22:17008725-17008805 37 1.34e-05 cctggccctg ctctgcct tgttcctggc chr7:152434122-152434202 12 1.34e-05 tcactgcaac ctctgcct cccaggttca chr21:44368757-44368837 73 1.34e-05 ctcttcctct ctctgcct chr11:34453438-34453518 70 1.34e-05 TTAGCTAAGT CTCTGCCT GCC chr7:155389832-155389912 20 1.34e-05 tcactgcaac ctctgcct cccaggttca chr22:22426591-22426671 30 1.34e-05 TTTGAAGCAG CTCTGCCT TCTTTTTGGG chr1:4188372-4188452 34 1.34e-05 ctgactcttt ctctgcct ccctgtctgt chr22:22693329-22693409 24 1.34e-05 tcactgcaac ctctgcct cctgggttca chr22:22077702-22077782 37 1.34e-05 tcactgcagt ctctgcct cctgggttca chr7:137690841-137690921 58 1.34e-05 CTCTAATGTT CTCTGCCT CCTCTCTTTC chr19:54929563-54929643 12 1.34e-05 cccttttgct ctctgcct ttttctgact chr12:94930056-94930136 35 2.68e-05 ggcttcctca ctcttcct caatcatacc chr17:44328239-44328319 14 2.68e-05 cctcttcctt ctcttcct cttcctcttc chr22:23158413-23158493 31 2.68e-05 TATACACATC CTCTTCCT AGATGGGGTA chr1:40600459-40600539 60 2.68e-05 cctcatcctc ctcttcct cctcctcctc chr22:23004569-23004649 59 2.68e-05 ggtctcaaga ctcttcct cagtataaca chr19:8197792-8197872 4 2.68e-05 ctc ctcttcct cgccgtccct chr7:139889609-139889689 62 4.07e-05 cagagcaaga ctctgtct caaaaagaaa chr13:90503975-90504055 63 4.07e-05 tggagtcttg ctctgtct tccaggctgg chr13:91489048-91489128 39 8.21e-05 attctcctgc ctcagcct cccaagtagc chr1:1520586-1520666 27 8.21e-05 attctcctgc ctcagcct ctagactagc chr1:227746872-227746952 64 8.21e-05 ttacctcgcg ctctttct gtcaccttt chr22:23361658-23361738 67 8.21e-05 atcctcccac ctcagcct cccaag chr13:81310125-81310205 26 8.21e-05 tttttctttt ctctttct ttttttttca chr6:29527886-29527966 25 8.21e-05 accccaatct ctctgcca tctccacgcc chr17:28428985-28429065 15 8.21e-05 agttagcatc ctctttct ctctcaagtg chr22:23378980-23379060 21 1.10e-04 TTGGCCCTGG CTCTTCCA GTGACCTCAT chr6:39268581-39268661 40 1.10e-04 gttaccttcc ctcatcct gcagacctca chr6:112430584-112430664 46 1.51e-04 GGCAGCTGTG CTCTGTCA TGTCAGGCTG chr1:162460781-162460861 9 1.51e-04 CCCATATG CTCTCCCT CTCCTCTTCC chr22:23287573-23287653 3 1.51e-04 gg ctctgtca cccaggctgg chr13:92231711-92231791 36 1.51e-04 TTATCCTCAG CTCTGTCA TCTGAACCAC chr17:74006031-74006111 21 1.94e-04 CCTTGACTAC CTCTTTCA CCACGACCTT chr22:21419607-21419687 40 1.94e-04 ACACTTTGTT CTCATTCT CTTTTTTTTT chr22:23381775-23381855 45 1.94e-04 aaaaaaaacc ctcagcca aattaaattt chr21:46967451-46967531 57 1.94e-04 ttgataataa ctctttca accaattgcc chr7:138137973-138138053 30 1.94e-04 CATTGTCTTC CTCATTCT CACCCTCTTT chr8:12404300-12404380 10 1.94e-04 cgttcactg ctcagcca ctctcctgac chr1:3676822-3676902 67 2.07e-04 tccttctctC CTCTCTCT CCCCCT chr22:23418194-23418274 26 2.62e-04 CATGGTCCCT CTCACCCT GGTTGGTCAT -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTCTKCCT MEME-1 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr13:81256343-81256423 1.3e-05 17_[+1]_55 chr7:117612058-117612138 1.3e-05 46_[+1]_26 chr22:17008725-17008805 1.3e-05 36_[+1]_36 chr7:152434122-152434202 1.3e-05 11_[+1]_61 chr21:44368757-44368837 1.3e-05 72_[+1] chr11:34453438-34453518 1.3e-05 69_[+1]_3 chr7:155389832-155389912 1.3e-05 19_[+1]_53 chr22:22426591-22426671 1.3e-05 29_[+1]_43 chr1:4188372-4188452 1.3e-05 33_[+1]_39 chr22:22693329-22693409 1.3e-05 23_[+1]_49 chr22:22077702-22077782 1.3e-05 36_[+1]_36 chr7:137690841-137690921 1.3e-05 57_[+1]_15 chr19:54929563-54929643 1.3e-05 11_[+1]_61 chr12:94930056-94930136 2.7e-05 34_[+1]_38 chr17:44328239-44328319 2.7e-05 13_[+1]_59 chr22:23158413-23158493 2.7e-05 30_[+1]_42 chr1:40600459-40600539 2.7e-05 59_[+1]_13 chr22:23004569-23004649 2.7e-05 58_[+1]_14 chr19:8197792-8197872 2.7e-05 3_[+1]_69 chr7:139889609-139889689 4.1e-05 61_[+1]_11 chr13:90503975-90504055 4.1e-05 62_[+1]_10 chr13:91489048-91489128 8.2e-05 38_[+1]_34 chr1:1520586-1520666 8.2e-05 26_[+1]_46 chr1:227746872-227746952 8.2e-05 63_[+1]_9 chr22:23361658-23361738 8.2e-05 66_[+1]_6 chr13:81310125-81310205 8.2e-05 25_[+1]_47 chr6:29527886-29527966 8.2e-05 24_[+1]_48 chr17:28428985-28429065 8.2e-05 14_[+1]_58 chr22:23378980-23379060 0.00011 20_[+1]_52 chr6:39268581-39268661 0.00011 39_[+1]_33 chr6:112430584-112430664 0.00015 45_[+1]_27 chr1:162460781-162460861 0.00015 8_[+1]_64 chr22:23287573-23287653 0.00015 2_[+1]_70 chr13:92231711-92231791 0.00015 35_[+1]_37 chr17:74006031-74006111 0.00019 20_[+1]_52 chr22:21419607-21419687 0.00019 39_[+1]_33 chr22:23381775-23381855 0.00019 44_[+1]_28 chr21:46967451-46967531 0.00019 56_[+1]_16 chr7:138137973-138138053 0.00019 29_[+1]_43 chr8:12404300-12404380 0.00019 9_[+1]_63 chr1:3676822-3676902 0.00021 66_[+1]_6 chr22:23418194-23418274 0.00026 25_[+1]_47 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTCTKCCT MEME-1 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF CTCTKCCT width=8 seqs=42 chr13:81256343-81256423 ( 18) CTCTGCCT 1 chr7:117612058-117612138 ( 47) CTCTGCCT 1 chr22:17008725-17008805 ( 37) CTCTGCCT 1 chr7:152434122-152434202 ( 12) CTCTGCCT 1 chr21:44368757-44368837 ( 73) CTCTGCCT 1 chr11:34453438-34453518 ( 70) CTCTGCCT 1 chr7:155389832-155389912 ( 20) CTCTGCCT 1 chr22:22426591-22426671 ( 30) CTCTGCCT 1 chr1:4188372-4188452 ( 34) CTCTGCCT 1 chr22:22693329-22693409 ( 24) CTCTGCCT 1 chr22:22077702-22077782 ( 37) CTCTGCCT 1 chr7:137690841-137690921 ( 58) CTCTGCCT 1 chr19:54929563-54929643 ( 12) CTCTGCCT 1 chr12:94930056-94930136 ( 35) CTCTTCCT 1 chr17:44328239-44328319 ( 14) CTCTTCCT 1 chr22:23158413-23158493 ( 31) CTCTTCCT 1 chr1:40600459-40600539 ( 60) CTCTTCCT 1 chr22:23004569-23004649 ( 59) CTCTTCCT 1 chr19:8197792-8197872 ( 4) CTCTTCCT 1 chr7:139889609-139889689 ( 62) CTCTGTCT 1 chr13:90503975-90504055 ( 63) CTCTGTCT 1 chr13:91489048-91489128 ( 39) CTCAGCCT 1 chr1:1520586-1520666 ( 27) CTCAGCCT 1 chr1:227746872-227746952 ( 64) CTCTTTCT 1 chr22:23361658-23361738 ( 67) CTCAGCCT 1 chr13:81310125-81310205 ( 26) CTCTTTCT 1 chr6:29527886-29527966 ( 25) CTCTGCCA 1 chr17:28428985-28429065 ( 15) CTCTTTCT 1 chr22:23378980-23379060 ( 21) CTCTTCCA 1 chr6:39268581-39268661 ( 40) CTCATCCT 1 chr6:112430584-112430664 ( 46) CTCTGTCA 1 chr1:162460781-162460861 ( 9) CTCTCCCT 1 chr22:23287573-23287653 ( 3) CTCTGTCA 1 chr13:92231711-92231791 ( 36) CTCTGTCA 1 chr17:74006031-74006111 ( 21) CTCTTTCA 1 chr22:21419607-21419687 ( 40) CTCATTCT 1 chr22:23381775-23381855 ( 45) CTCAGCCA 1 chr21:46967451-46967531 ( 57) CTCTTTCA 1 chr7:138137973-138138053 ( 30) CTCATTCT 1 chr8:12404300-12404380 ( 10) CTCAGCCA 1 chr1:3676822-3676902 ( 67) CTCTCTCT 1 chr22:23418194-23418274 ( 26) CTCACCCT 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTCTKCCT MEME-1 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 10.8329 E= 2.8e-015 -1204 205 -1204 -1204 -1204 -1204 -1204 200 -1204 205 -1204 -1204 -26 -1204 -1204 165 -1204 -175 119 51 -1204 152 -1204 30 -1204 205 -1204 -1204 -26 -1204 -1204 165 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTCTKCCT MEME-1 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 42 E= 2.8e-015 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 0.214286 0.000000 0.000000 0.785714 0.000000 0.071429 0.571429 0.357143 0.000000 0.690476 0.000000 0.309524 0.000000 1.000000 0.000000 0.000000 0.214286 0.000000 0.000000 0.785714 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTCTKCCT MEME-1 regular expression -------------------------------------------------------------------------------- CTC[TA][GT][CT]C[TA] -------------------------------------------------------------------------------- Time 4.98 secs. ******************************************************************************** ******************************************************************************** MOTIF YCCAGCCT MEME-2 width = 8 sites = 45 llr = 356 E-value = 2.8e-003 ******************************************************************************** -------------------------------------------------------------------------------- Motif YCCAGCCT MEME-2 Description -------------------------------------------------------------------------------- Simplified A :::7:::2 pos.-specific C 39a::7a1 probability G 1:::a3:: matrix T 61:3:::7 bits 2.1 * * 1.8 * * * 1.6 ** * * 1.4 ** * * Relative 1.2 ** *** Entropy 1.0 ****** (11.4 bits) 0.8 ******** 0.6 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel TCCAGCCT consensus C T G sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YCCAGCCT MEME-2 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr22:19757333-19757413 21 1.37e-05 ctcacagacc tccagcct ccagaactgg chr16:24541168-24541248 43 1.37e-05 gccactgcac tccagcct gggcaacaga chr22:23423970-23424050 5 1.37e-05 gcat tccagcct gggcaacaga chr10:76842639-76842719 28 1.37e-05 accactgcgc tccagcct gggtagcagt chr7:139889609-139889689 38 1.37e-05 gccactgcac tccagcct gggtgacaga chr1:29464626-29464706 6 1.37e-05 tgcac tccagcct gagtgataaa chr21:33769146-33769226 58 1.37e-05 gccattgcac tccagcct gggcgacgag chr22:23463992-23464072 31 2.69e-05 attctcctgc cccagcct cccaaggagc chr5:110103997-110104077 5 2.69e-05 tctt cccagcct ttctctgact chr7:117612058-117612138 73 4.03e-05 caagtggttc tcctgcct chr22:20955517-20955597 66 4.03e-05 caagtgattc tcctgcct ctcccga chr7:152434122-152434202 38 4.03e-05 caagcgattc tcctgcct cagcctcccg chr22:23280898-23280978 69 4.03e-05 agtgtgactg tcctgcct gtgt chr22:22077702-22077782 63 4.03e-05 caagccattc tcctgcct cagcctccag chr13:81310125-81310205 65 5.45e-05 tactctgttg tccaggct ggagtgtg chr22:23135412-23135492 22 5.45e-05 ATCTCTGGGC TCCAGGCT GAGGATGAGG chr19:8197792-8197872 65 5.45e-05 CCAGTCTGGC TCCAGGCT CACCCATG chr13:92270043-92270123 27 5.45e-05 tagtaaacat tccaggct ttgcaagtca chr13:90503975-90504055 71 5.45e-05 tgctctgtct tccaggct gg chr7:100643412-100643492 17 8.11e-05 TCCACAGCGG CCCAGGCT CCACTGAAAC chr22:23287573-23287653 11 8.11e-05 ggctctgtca cccaggct ggagtgcagc chr2:157267821-157267901 47 8.11e-05 attcttgtca cccaggct ggagtgcaat chr13:92382259-92382339 40 9.51e-05 tccctgacca tccagcca tgtttagcca chr16:33418464-33418544 49 1.22e-04 tagatgtgta tcctggct ttccaccacc chr22:17008725-17008805 65 1.22e-04 cctgatcctt tcctggct ctgcactg chr19:51311654-51311734 73 1.22e-04 atccccatta tccagccc chr7:150846871-150846951 22 1.36e-04 TTCCATGGCT CCCAGCCA TGCAGCACCT chr22:23439522-23439602 44 1.36e-04 GGACCTGTGC CCCAGCCA GGGAACCTGG chr13:90946173-90946253 12 1.64e-04 agtactggca gccagcct gcaaatgtaa chr22:22564256-22564336 72 1.64e-04 TGAGGAGCAG TTCAGCCT T chr10:47084373-47084453 21 1.64e-04 ttgactcctc ttcagcct ttgagccctg chr13:91946847-91946927 35 1.90e-04 agccactgcg cccagccC ACATAGTGAT chr19:16217266-16217346 17 2.31e-04 TTGGACTTTA TCCTGCCC AGAGACCACA chr6:36279100-36279180 7 2.31e-04 gggtat tccaggca cacgggatgg chr7:155389832-155389912 52 2.45e-04 attctcccac ctcagcct cccaagtagc chr22:22693329-22693409 56 2.45e-04 attctcatgc ctcagcct cccaagtagc chr13:91489048-91489128 11 2.72e-04 caacctctgc ccctgcca ggttcaagca chr22:22390362-22390442 56 2.72e-04 ACAGATCAGG CCCTGCCA GTAAGTAAGC chr6:31682144-31682224 29 2.72e-04 CTGTAATTAT CCCTGCCA GCTTTACTAC chr3:170402799-170402879 24 2.99e-04 CTatagcata gcctgcct ttgctggagt chr22:22410142-22410222 70 2.99e-04 atgaatgttg gcctgcct tgc chr6:38684164-38684244 62 2.99e-04 tgttcccacc ttctgcct ataatgtttc chr22:22471940-22472020 58 3.68e-04 GAGGCGGGAG CCCAGGCC AATGTAGAAG chr22:22732891-22732971 63 3.68e-04 CCTTGGGTGG CCCAGGCC CAGCTGTCCT chr7:127754091-127754171 31 4.80e-04 CAGTCCACTC TCCAGCTT AAAAAAGTTC -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YCCAGCCT MEME-2 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr22:19757333-19757413 1.4e-05 20_[+2]_52 chr16:24541168-24541248 1.4e-05 42_[+2]_30 chr22:23423970-23424050 1.4e-05 4_[+2]_68 chr10:76842639-76842719 1.4e-05 27_[+2]_45 chr7:139889609-139889689 1.4e-05 37_[+2]_35 chr1:29464626-29464706 1.4e-05 5_[+2]_67 chr21:33769146-33769226 1.4e-05 57_[+2]_15 chr22:23463992-23464072 2.7e-05 30_[+2]_42 chr5:110103997-110104077 2.7e-05 4_[+2]_68 chr7:117612058-117612138 4e-05 72_[+2] chr22:20955517-20955597 4e-05 65_[+2]_7 chr7:152434122-152434202 4e-05 37_[+2]_35 chr22:23280898-23280978 4e-05 68_[+2]_4 chr22:22077702-22077782 4e-05 62_[+2]_10 chr13:81310125-81310205 5.5e-05 64_[+2]_8 chr22:23135412-23135492 5.5e-05 21_[+2]_51 chr19:8197792-8197872 5.5e-05 64_[+2]_8 chr13:92270043-92270123 5.5e-05 26_[+2]_46 chr13:90503975-90504055 5.5e-05 70_[+2]_2 chr7:100643412-100643492 8.1e-05 16_[+2]_56 chr22:23287573-23287653 8.1e-05 10_[+2]_62 chr2:157267821-157267901 8.1e-05 46_[+2]_26 chr13:92382259-92382339 9.5e-05 39_[+2]_33 chr16:33418464-33418544 0.00012 48_[+2]_24 chr22:17008725-17008805 0.00012 64_[+2]_8 chr19:51311654-51311734 0.00012 72_[+2] chr7:150846871-150846951 0.00014 21_[+2]_51 chr22:23439522-23439602 0.00014 43_[+2]_29 chr13:90946173-90946253 0.00016 11_[+2]_61 chr22:22564256-22564336 0.00016 71_[+2]_1 chr10:47084373-47084453 0.00016 20_[+2]_52 chr13:91946847-91946927 0.00019 34_[+2]_38 chr19:16217266-16217346 0.00023 16_[+2]_56 chr6:36279100-36279180 0.00023 6_[+2]_66 chr7:155389832-155389912 0.00024 51_[+2]_21 chr22:22693329-22693409 0.00024 55_[+2]_17 chr13:91489048-91489128 0.00027 10_[+2]_62 chr22:22390362-22390442 0.00027 55_[+2]_17 chr6:31682144-31682224 0.00027 28_[+2]_44 chr3:170402799-170402879 0.0003 23_[+2]_49 chr22:22410142-22410222 0.0003 69_[+2]_3 chr6:38684164-38684244 0.0003 61_[+2]_11 chr22:22471940-22472020 0.00037 57_[+2]_15 chr22:22732891-22732971 0.00037 62_[+2]_10 chr7:127754091-127754171 0.00048 30_[+2]_42 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YCCAGCCT MEME-2 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF YCCAGCCT width=8 seqs=45 chr22:19757333-19757413 ( 21) TCCAGCCT 1 chr16:24541168-24541248 ( 43) TCCAGCCT 1 chr22:23423970-23424050 ( 5) TCCAGCCT 1 chr10:76842639-76842719 ( 28) TCCAGCCT 1 chr7:139889609-139889689 ( 38) TCCAGCCT 1 chr1:29464626-29464706 ( 6) TCCAGCCT 1 chr21:33769146-33769226 ( 58) TCCAGCCT 1 chr22:23463992-23464072 ( 31) CCCAGCCT 1 chr5:110103997-110104077 ( 5) CCCAGCCT 1 chr7:117612058-117612138 ( 73) TCCTGCCT 1 chr22:20955517-20955597 ( 66) TCCTGCCT 1 chr7:152434122-152434202 ( 38) TCCTGCCT 1 chr22:23280898-23280978 ( 69) TCCTGCCT 1 chr22:22077702-22077782 ( 63) TCCTGCCT 1 chr13:81310125-81310205 ( 65) TCCAGGCT 1 chr22:23135412-23135492 ( 22) TCCAGGCT 1 chr19:8197792-8197872 ( 65) TCCAGGCT 1 chr13:92270043-92270123 ( 27) TCCAGGCT 1 chr13:90503975-90504055 ( 71) TCCAGGCT 1 chr7:100643412-100643492 ( 17) CCCAGGCT 1 chr22:23287573-23287653 ( 11) CCCAGGCT 1 chr2:157267821-157267901 ( 47) CCCAGGCT 1 chr13:92382259-92382339 ( 40) TCCAGCCA 1 chr16:33418464-33418544 ( 49) TCCTGGCT 1 chr22:17008725-17008805 ( 65) TCCTGGCT 1 chr19:51311654-51311734 ( 73) TCCAGCCC 1 chr7:150846871-150846951 ( 22) CCCAGCCA 1 chr22:23439522-23439602 ( 44) CCCAGCCA 1 chr13:90946173-90946253 ( 12) GCCAGCCT 1 chr22:22564256-22564336 ( 72) TTCAGCCT 1 chr10:47084373-47084453 ( 21) TTCAGCCT 1 chr13:91946847-91946927 ( 35) CCCAGCCC 1 chr19:16217266-16217346 ( 17) TCCTGCCC 1 chr6:36279100-36279180 ( 7) TCCAGGCA 1 chr7:155389832-155389912 ( 52) CTCAGCCT 1 chr22:22693329-22693409 ( 56) CTCAGCCT 1 chr13:91489048-91489128 ( 11) CCCTGCCA 1 chr22:22390362-22390442 ( 56) CCCTGCCA 1 chr6:31682144-31682224 ( 29) CCCTGCCA 1 chr3:170402799-170402879 ( 24) GCCTGCCT 1 chr22:22410142-22410222 ( 70) GCCTGCCT 1 chr6:38684164-38684244 ( 62) TTCTGCCT 1 chr22:22471940-22472020 ( 58) CCCAGGCC 1 chr22:22732891-22732971 ( 63) CCCAGGCC 1 chr7:127754091-127754171 ( 31) TCCAGCTT 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YCCAGCCT MEME-2 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 9.04017 E= 2.8e-003 -1214 47 -191 126 -1214 188 -1214 -117 -1214 205 -1214 -1214 142 -1214 -1214 31 -1214 -1214 200 -1214 -1214 156 20 -1214 -1214 202 -1214 -349 -73 -112 -1214 155 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YCCAGCCT MEME-2 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 45 E= 2.8e-003 0.000000 0.333333 0.066667 0.600000 0.000000 0.888889 0.000000 0.111111 0.000000 1.000000 0.000000 0.000000 0.688889 0.000000 0.000000 0.311111 0.000000 0.000000 1.000000 0.000000 0.000000 0.711111 0.288889 0.000000 0.000000 0.977778 0.000000 0.022222 0.155556 0.111111 0.000000 0.733333 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YCCAGCCT MEME-2 regular expression -------------------------------------------------------------------------------- [TC]CC[AT]G[CG]CT -------------------------------------------------------------------------------- Time 8.73 secs. ******************************************************************************** ******************************************************************************** MOTIF KGAGGSWG MEME-3 width = 8 sites = 61 llr = 454 E-value = 2.8e-005 ******************************************************************************** -------------------------------------------------------------------------------- Motif KGAGGSWG MEME-3 Description -------------------------------------------------------------------------------- Simplified A 2:a2216: pos.-specific C :::::6:: probability G 5a:883:a matrix T 3:::::4: bits 2.1 ** * 1.8 ** * 1.6 ** * 1.4 *** * Relative 1.2 **** * Entropy 1.0 **** ** (10.7 bits) 0.8 **** ** 0.6 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel GGAGGCAG consensus T GT sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif KGAGGSWG MEME-3 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr1:197835621-197835701 60 1.59e-05 cttgaacctg ggaggcag aagttgaagt chr22:22362796-22362876 59 1.59e-05 cttgagccca ggaggcag aggttgcagt chr1:145080541-145080621 13 1.59e-05 cttaaatctg ggaggcag atgttgcagt chr7:138995401-138995481 44 1.59e-05 cttgcaccta ggaggcag aggttgcagt chr17:56763701-56763781 40 1.59e-05 tgtggttcat ggaggcag gaaatgcagg chr21:33769146-33769226 17 1.59e-05 cttgaacctg ggaggcag aggttgcagt chr22:21913507-21913587 24 3.13e-05 cagctactcg ggaggctg aggcaggaga chr22:23418194-23418274 62 3.13e-05 TGGCTGAGGA GGAGGCTG TGCTGGAGGC chr15:20864827-20864907 56 3.13e-05 cccaggaggt ggaggctg ccgtgagccg chr21:43812448-43812528 69 3.13e-05 TCGCAGATGT GGAGGCTG TGAG chr12:101917302-10191738 12 3.13e-05 cagctgcttg ggaggctg aagcaggaga chr10:59946741-59946821 10 3.13e-05 cggactaag ggaggctg agggaggagg chr15:79329093-79329173 58 6.37e-05 aggaagaaag ggagggag agagaACAGA chr22:23327020-23327100 31 6.37e-05 CTTGCTGGGT GGAGGGAG TACGTATTGC chr15:39803446-39803526 39 6.37e-05 agggaagcat ggagggag gaagagatgg chr1:101212056-101212136 58 6.37e-05 aaagaaagag ggagggag gaaggaagga chr17:28799748-28799828 38 6.37e-05 tgtgacttaa tgaggcag tctttgaaac chr22:23380507-23380587 36 9.53e-05 gtggtgTCGG GGAGGGTG GAGGAATTGG chr5:71186298-71186378 68 9.53e-05 CAGCCTTGTG GGAGGGTG CCTTG chr22:22434558-22434638 38 9.53e-05 AGCCTGAAGA TGAGGCTG ATTATCACTG chr7:158517360-158517440 41 9.53e-05 GACAAGGAGG GGAGGGTG CCACATTCTG chr22:23135412-23135492 35 9.53e-05 AGGCTGAGGA TGAGGCTG ATTATTACTG chr22:21330736-21330816 41 9.53e-05 AATCGCGTGG TGAGGCTG GCCCGAGGCC chr10:47014275-47014355 25 1.12e-04 cagaagaaag agaggcag agagacagtg chr22:21053237-21053317 35 1.12e-04 CCACCAGGAG AGAGGCAG AGGGGCTGTG chr22:22097940-22098020 44 1.27e-04 agccagggag agaggctg cagaagaaac chr9:140811202-140811282 10 1.61e-04 GTTTGGCTG TGAGGGAG AGGAACGGTC chr1:206285175-206285255 69 1.61e-04 tctgacaccg ggaggaag gtgg chr16:31109757-31109837 33 1.61e-04 gtttgaagat ggaggaag gggattgtga chr22:21018983-21019063 72 1.61e-04 tgcctggggt tgagggag g chr6:130504905-130504985 58 1.77e-04 GGGAAGACAA Ggagacag agagagaaag chr17:63123766-63123846 61 2.26e-04 atggacaaga ggaggatg tgggtaaggt chr16:24541168-24541248 2 2.26e-04 g ggaagcag aggttgcagt chr22:23451098-23451178 36 2.26e-04 AGGAATTGTC TGAGGGTG ACCAGTGGGG chr22:23502597-23502677 16 2.26e-04 TCTACCTGGA GGAGGATG CATAAAGGCT chr22:20175758-20175838 49 2.26e-04 AGAGTGTCAG GGAAGCAG TGGGAACTCG chr7:139915101-139915181 39 2.59e-04 ggggaaggga ggagactg tagcgatgcc chr22:20723811-20723891 60 2.59e-04 TCCACCTGCA AGAGGGAG AGCGGAGAGG chr1:48080800-48080880 16 2.59e-04 agagagagag agagggag agaAGTAGCT chr22:23378980-23379060 44 2.75e-04 CTCATCCACA GGAAGCTG ATTGTGTCCT chr1:180569496-180569576 32 2.91e-04 acagagacag agagggtg aaaagagaga chr1:17024028-17024108 73 2.91e-04 CACCCAGGGC AGAGGGTG chr7:116073060-116073140 1 3.08e-04 . TGAGGAAG CTAAGAATAC chr6:35756501-35756581 44 3.41e-04 GTGTGGGGTT GGAGAGAG AATGAGTCAA chr16:33418464-33418544 29 3.41e-04 ggttctgcac tgagacag tctagatgtg chr22:22382974-22383054 63 3.41e-04 gttttgtttt tgagacag tgtctcactc chr2:55925975-55926055 8 3.91e-04 gcttctc tgaggatg tggaaaagcc chr22:22426591-22426671 22 3.91e-04 GCAAGGGATT TGAAGCAG CTCTGCCTTC chr22:22520868-22520948 18 3.91e-04 GCGTCAGGGC TGAGGATG AAGGGACCAG chr22:22365170-22365250 64 4.41e-04 ccagtctgcc tgagactg cggggtttt chr13:91717001-91717081 42 4.41e-04 TGGGGAGTCA GGAGAGTG AGAAACAGTG chr1:12606621-12606701 33 4.90e-04 cctgggccac agagacag actatgtctc chr22:23081571-23081651 61 4.90e-04 AGGTTGAACA TGAAGCTG ACTATTACCG chr2:149365343-149365423 29 4.90e-04 AGTGGTTAGC AGAGACAG GGTGGCTGGG chr22:22564256-22564336 53 4.90e-04 AGGAGTGTTA GGAAGGTG ATGAGGAGCA chr22:22756009-22756089 62 5.23e-04 ATGAACTGGG AGAAGCAG TGGTGGAAAT chr6:27590800-27590880 35 5.23e-04 GTGGACATAA AGAAGCAG ACAGTACAAG chr22:17197483-17197563 21 5.23e-04 aggtgccact agaagcag aaaaaggcaa chr1:22372037-22372117 23 6.24e-04 gttcatggtg ggaagaag agtggacTTG chr1:192252891-192252971 18 6.74e-04 gttatccagg tgagagtg aaggggagaa chr17:44328239-44328319 68 8.09e-04 cttgtttgtt tgagaaag gttct -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif KGAGGSWG MEME-3 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr1:197835621-197835701 1.6e-05 59_[+3]_13 chr22:22362796-22362876 1.6e-05 58_[+3]_14 chr1:145080541-145080621 1.6e-05 12_[+3]_60 chr7:138995401-138995481 1.6e-05 43_[+3]_29 chr17:56763701-56763781 1.6e-05 39_[+3]_33 chr21:33769146-33769226 1.6e-05 16_[+3]_56 chr22:21913507-21913587 3.1e-05 23_[+3]_49 chr22:23418194-23418274 3.1e-05 61_[+3]_11 chr15:20864827-20864907 3.1e-05 55_[+3]_17 chr21:43812448-43812528 3.1e-05 68_[+3]_4 chr12:101917302-10191738 3.1e-05 11_[+3]_61 chr10:59946741-59946821 3.1e-05 9_[+3]_63 chr15:79329093-79329173 6.4e-05 57_[+3]_15 chr22:23327020-23327100 6.4e-05 30_[+3]_42 chr15:39803446-39803526 6.4e-05 38_[+3]_34 chr1:101212056-101212136 6.4e-05 57_[+3]_15 chr17:28799748-28799828 6.4e-05 37_[+3]_35 chr22:23380507-23380587 9.5e-05 35_[+3]_37 chr5:71186298-71186378 9.5e-05 67_[+3]_5 chr22:22434558-22434638 9.5e-05 37_[+3]_35 chr7:158517360-158517440 9.5e-05 40_[+3]_32 chr22:23135412-23135492 9.5e-05 34_[+3]_38 chr22:21330736-21330816 9.5e-05 40_[+3]_32 chr10:47014275-47014355 0.00011 24_[+3]_48 chr22:21053237-21053317 0.00011 34_[+3]_38 chr22:22097940-22098020 0.00013 43_[+3]_29 chr9:140811202-140811282 0.00016 9_[+3]_63 chr1:206285175-206285255 0.00016 68_[+3]_4 chr16:31109757-31109837 0.00016 32_[+3]_40 chr22:21018983-21019063 0.00016 71_[+3]_1 chr6:130504905-130504985 0.00018 57_[+3]_15 chr17:63123766-63123846 0.00023 60_[+3]_12 chr16:24541168-24541248 0.00023 1_[+3]_71 chr22:23451098-23451178 0.00023 35_[+3]_37 chr22:23502597-23502677 0.00023 15_[+3]_57 chr22:20175758-20175838 0.00023 48_[+3]_24 chr7:139915101-139915181 0.00026 38_[+3]_34 chr22:20723811-20723891 0.00026 59_[+3]_13 chr1:48080800-48080880 0.00026 15_[+3]_57 chr22:23378980-23379060 0.00027 43_[+3]_29 chr1:180569496-180569576 0.00029 31_[+3]_41 chr1:17024028-17024108 0.00029 72_[+3] chr7:116073060-116073140 0.00031 [+3]_72 chr6:35756501-35756581 0.00034 43_[+3]_29 chr16:33418464-33418544 0.00034 28_[+3]_44 chr22:22382974-22383054 0.00034 62_[+3]_10 chr2:55925975-55926055 0.00039 7_[+3]_65 chr22:22426591-22426671 0.00039 21_[+3]_51 chr22:22520868-22520948 0.00039 17_[+3]_55 chr22:22365170-22365250 0.00044 63_[+3]_9 chr13:91717001-91717081 0.00044 41_[+3]_31 chr1:12606621-12606701 0.00049 32_[+3]_40 chr22:23081571-23081651 0.00049 60_[+3]_12 chr2:149365343-149365423 0.00049 28_[+3]_44 chr22:22564256-22564336 0.00049 52_[+3]_20 chr22:22756009-22756089 0.00052 61_[+3]_11 chr6:27590800-27590880 0.00052 34_[+3]_38 chr22:17197483-17197563 0.00052 20_[+3]_52 chr1:22372037-22372117 0.00062 22_[+3]_50 chr1:192252891-192252971 0.00067 17_[+3]_55 chr17:44328239-44328319 0.00081 67_[+3]_5 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif KGAGGSWG MEME-3 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF KGAGGSWG width=8 seqs=61 chr1:197835621-197835701 ( 60) GGAGGCAG 1 chr22:22362796-22362876 ( 59) GGAGGCAG 1 chr1:145080541-145080621 ( 13) GGAGGCAG 1 chr7:138995401-138995481 ( 44) GGAGGCAG 1 chr17:56763701-56763781 ( 40) GGAGGCAG 1 chr21:33769146-33769226 ( 17) GGAGGCAG 1 chr22:21913507-21913587 ( 24) GGAGGCTG 1 chr22:23418194-23418274 ( 62) GGAGGCTG 1 chr15:20864827-20864907 ( 56) GGAGGCTG 1 chr21:43812448-43812528 ( 69) GGAGGCTG 1 chr12:101917302-10191738 ( 12) GGAGGCTG 1 chr10:59946741-59946821 ( 10) GGAGGCTG 1 chr15:79329093-79329173 ( 58) GGAGGGAG 1 chr22:23327020-23327100 ( 31) GGAGGGAG 1 chr15:39803446-39803526 ( 39) GGAGGGAG 1 chr1:101212056-101212136 ( 58) GGAGGGAG 1 chr17:28799748-28799828 ( 38) TGAGGCAG 1 chr22:23380507-23380587 ( 36) GGAGGGTG 1 chr5:71186298-71186378 ( 68) GGAGGGTG 1 chr22:22434558-22434638 ( 38) TGAGGCTG 1 chr7:158517360-158517440 ( 41) GGAGGGTG 1 chr22:23135412-23135492 ( 35) TGAGGCTG 1 chr22:21330736-21330816 ( 41) TGAGGCTG 1 chr10:47014275-47014355 ( 25) AGAGGCAG 1 chr22:21053237-21053317 ( 35) AGAGGCAG 1 chr22:22097940-22098020 ( 44) AGAGGCTG 1 chr9:140811202-140811282 ( 10) TGAGGGAG 1 chr1:206285175-206285255 ( 69) GGAGGAAG 1 chr16:31109757-31109837 ( 33) GGAGGAAG 1 chr22:21018983-21019063 ( 72) TGAGGGAG 1 chr6:130504905-130504985 ( 58) GGAGACAG 1 chr17:63123766-63123846 ( 61) GGAGGATG 1 chr16:24541168-24541248 ( 2) GGAAGCAG 1 chr22:23451098-23451178 ( 36) TGAGGGTG 1 chr22:23502597-23502677 ( 16) GGAGGATG 1 chr22:20175758-20175838 ( 49) GGAAGCAG 1 chr7:139915101-139915181 ( 39) GGAGACTG 1 chr22:20723811-20723891 ( 60) AGAGGGAG 1 chr1:48080800-48080880 ( 16) AGAGGGAG 1 chr22:23378980-23379060 ( 44) GGAAGCTG 1 chr1:180569496-180569576 ( 32) AGAGGGTG 1 chr1:17024028-17024108 ( 73) AGAGGGTG 1 chr7:116073060-116073140 ( 1) TGAGGAAG 1 chr6:35756501-35756581 ( 44) GGAGAGAG 1 chr16:33418464-33418544 ( 29) TGAGACAG 1 chr22:22382974-22383054 ( 63) TGAGACAG 1 chr2:55925975-55926055 ( 8) TGAGGATG 1 chr22:22426591-22426671 ( 22) TGAAGCAG 1 chr22:22520868-22520948 ( 18) TGAGGATG 1 chr22:22365170-22365250 ( 64) TGAGACTG 1 chr13:91717001-91717081 ( 42) GGAGAGTG 1 chr1:12606621-12606701 ( 33) AGAGACAG 1 chr22:23081571-23081651 ( 61) TGAAGCTG 1 chr2:149365343-149365423 ( 29) AGAGACAG 1 chr22:22564256-22564336 ( 53) GGAAGGTG 1 chr22:22756009-22756089 ( 62) AGAAGCAG 1 chr6:27590800-27590880 ( 35) AGAAGCAG 1 chr22:17197483-17197563 ( 21) AGAAGCAG 1 chr1:22372037-22372117 ( 23) GGAAGAAG 1 chr1:192252891-192252971 ( 18) TGAGAGTG 1 chr17:44328239-44328319 ( 68) TGAGAAAG 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif KGAGGSWG MEME-3 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 9.50978 E= 2.8e-005 -39 -1257 106 15 -1257 -1257 200 -1257 196 -1257 -1257 -1257 -65 -1257 174 -1257 -51 -1257 171 -1257 -80 121 23 -1257 111 -1257 -1257 82 -1257 -1257 200 -1257 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif KGAGGSWG MEME-3 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 61 E= 2.8e-005 0.196721 0.000000 0.524590 0.278689 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.163934 0.000000 0.836066 0.000000 0.180328 0.000000 0.819672 0.000000 0.147541 0.557377 0.295082 0.000000 0.557377 0.000000 0.000000 0.442623 0.000000 0.000000 1.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif KGAGGSWG MEME-3 regular expression -------------------------------------------------------------------------------- [GT]GAGG[CG][AT]G -------------------------------------------------------------------------------- Time 12.40 secs. ******************************************************************************** ******************************************************************************** MOTIF CAGDGAGM MEME-4 width = 8 sites = 43 llr = 334 E-value = 9.7e+001 ******************************************************************************** -------------------------------------------------------------------------------- Motif CAGDGAGM MEME-4 Description -------------------------------------------------------------------------------- Simplified A 1a:3:a:6 pos.-specific C 6:::::13 probability G 2:a2a:9: matrix T :::5:::1 bits 2.1 ** ** 1.8 ** ** 1.6 ** ** 1.4 ** *** Relative 1.2 ** *** Entropy 1.0 ** *** (11.2 bits) 0.8 *** *** 0.6 *** **** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel CAGTGAGA consensus G A C sequence G -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CAGDGAGM MEME-4 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr10:76842639-76842719 42 1.62e-05 gcctgggtag cagtgaga ccctgtccca chr22:21913507-21913587 70 4.81e-05 gtggaggtta cagtgagc tga chr2:100116290-100116370 22 4.81e-05 aagagggagt cagagaga gaggaagaga chr16:24541168-24541248 16 4.81e-05 gcagaggttg cagtgagc caagatcacg chr22:22362796-22362876 73 4.81e-05 gcagaggttg cagtgagc chr1:145080541-145080621 27 4.81e-05 gcagatgttg cagtgagc caagatcaca chr7:73858766-73858846 55 4.81e-05 cagacaaagg cagagaGA TTGGAAGCAA chr6:130504905-130504985 20 4.81e-05 AAACACAGGG CAGAGAGA GACCAAGAAG chr7:151080882-151080962 52 4.81e-05 AGCTGGGCAA CAGTGAGC TGCAGGCTTC chr7:138995401-138995481 58 4.81e-05 gcagaggttg cagtgagc cgagatcgtg chr7:139889609-139889689 11 4.81e-05 atggaagttg cagtgagc cgaggtcacg chr21:33769146-33769226 31 4.81e-05 gcagaggttg cagtgagc tgacatcgtg chr11:108508187-10850826 72 6.43e-05 gtattgtgag cagggaga c chr22:22097940-22098020 12 6.43e-05 tgtgagcaca cagggaga agacgccatc chr7:143046983-143047063 35 6.43e-05 ACGTACACTG CAGGGAGA GGGTAGGGCA chr22:21053237-21053317 68 6.43e-05 CTAGAGTCCT CAGGGAGA GAGTG chr16:31109757-31109837 2 7.99e-05 a cagagagc tgcaatgttt chr6:35756501-35756581 1 9.68e-05 . GAGTGAGA AAGAAAGACT chr22:23423970-23424050 21 9.68e-05 ctgggcaaca gagtgaga ttccatctca chr22:23159043-23159123 13 9.68e-05 aggtgaaggt gagtgaga cttaatagct chr2:149365343-149365423 55 1.12e-04 GGTGTGTCAA CAGGGAGC AAGTCATGAA chr22:22569614-22569694 71 1.63e-04 GCCAGTGGGG AAGTGAGA TA chr15:79329093-79329173 11 1.63e-04 gagatagcaa gagagaga aaggggtgag chr10:47014275-47014355 45 1.63e-04 agacagtgaa gagagaga aagagagaga chr1:48080800-48080880 5 1.63e-04 gtga gagagaga gagagaggga chr1:180569496-180569576 44 1.63e-04 agggtgaaaa gagagaga gaggagaaga chr17:28799748-28799828 1 1.63e-04 . gagtgagc acaatttaaa chr22:23141231-23141311 16 1.63e-04 AAAGCAGAGA AAGTGAGA CTTTCCATTG chr9:140811202-140811282 47 2.11e-04 GTTTGGCCGT GAGGGAGA GGTACAGTCA chr22:21387233-21387313 2 2.11e-04 A CAGTGAGT TAGATGAAGA chr12:101917302-10191738 58 2.11e-04 gtggaggttg cagtgagt caagactgtg chr13:91796467-91796547 38 2.11e-04 TTGGCATTAG CAGTGACA TTGGCCCTGC chr21:46968182-46968262 46 2.11e-04 gaTCTGTGTC cagtgaca caggaagcaa chr22:22732891-22732971 38 2.61e-04 GAAGAGAAGC AAGAGAGA TGCTTAGCCT chr6:6700019-6700099 29 3.41e-04 AGAGTTAGTC AAGGGAGA GAACATGCAC chr21:46965536-46965616 55 3.41e-04 cacagagata cagagaca tacacatgca chr22:23002482-23002562 63 3.41e-04 CAGTGGTCAA CAGAGAGT CACATGGCAA chr3:14376240-14376320 16 3.41e-04 cacacgtaca cagagaca cacatgcaca chr7:158517360-158517440 73 3.41e-04 AAGTTGAGGA CAGAGAGT chr7:150059078-150059158 62 4.20e-04 gttccctagc aagggagc tgcttgatct chr8:2272284-2272364 41 4.20e-04 TAGTGACAGG AAGGGAGC TTCATCCTAC chr5:71186298-71186378 10 4.53e-04 TCAGTGTCT GAGTGACA AGGATGTCAC chr22:23165343-23165423 42 4.68e-04 GAAGGGGCCA CAGGGACC TCTGGGCTGA -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CAGDGAGM MEME-4 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr10:76842639-76842719 1.6e-05 41_[+4]_31 chr22:21913507-21913587 4.8e-05 69_[+4]_3 chr2:100116290-100116370 4.8e-05 21_[+4]_51 chr16:24541168-24541248 4.8e-05 15_[+4]_57 chr22:22362796-22362876 4.8e-05 72_[+4] chr1:145080541-145080621 4.8e-05 26_[+4]_46 chr7:73858766-73858846 4.8e-05 54_[+4]_18 chr6:130504905-130504985 4.8e-05 19_[+4]_53 chr7:151080882-151080962 4.8e-05 51_[+4]_21 chr7:138995401-138995481 4.8e-05 57_[+4]_15 chr7:139889609-139889689 4.8e-05 10_[+4]_62 chr21:33769146-33769226 4.8e-05 30_[+4]_42 chr11:108508187-10850826 6.4e-05 71_[+4]_1 chr22:22097940-22098020 6.4e-05 11_[+4]_61 chr7:143046983-143047063 6.4e-05 34_[+4]_38 chr22:21053237-21053317 6.4e-05 67_[+4]_5 chr16:31109757-31109837 8e-05 1_[+4]_71 chr6:35756501-35756581 9.7e-05 [+4]_72 chr22:23423970-23424050 9.7e-05 20_[+4]_52 chr22:23159043-23159123 9.7e-05 12_[+4]_60 chr2:149365343-149365423 0.00011 54_[+4]_18 chr22:22569614-22569694 0.00016 70_[+4]_2 chr15:79329093-79329173 0.00016 10_[+4]_62 chr10:47014275-47014355 0.00016 44_[+4]_28 chr1:48080800-48080880 0.00016 4_[+4]_68 chr1:180569496-180569576 0.00016 43_[+4]_29 chr17:28799748-28799828 0.00016 [+4]_72 chr22:23141231-23141311 0.00016 15_[+4]_57 chr9:140811202-140811282 0.00021 46_[+4]_26 chr22:21387233-21387313 0.00021 1_[+4]_71 chr12:101917302-10191738 0.00021 57_[+4]_15 chr13:91796467-91796547 0.00021 37_[+4]_35 chr21:46968182-46968262 0.00021 45_[+4]_27 chr22:22732891-22732971 0.00026 37_[+4]_35 chr6:6700019-6700099 0.00034 28_[+4]_44 chr21:46965536-46965616 0.00034 54_[+4]_18 chr22:23002482-23002562 0.00034 62_[+4]_10 chr3:14376240-14376320 0.00034 15_[+4]_57 chr7:158517360-158517440 0.00034 72_[+4] chr7:150059078-150059158 0.00042 61_[+4]_11 chr8:2272284-2272364 0.00042 40_[+4]_32 chr5:71186298-71186378 0.00045 9_[+4]_63 chr22:23165343-23165423 0.00047 41_[+4]_31 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CAGDGAGM MEME-4 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF CAGDGAGM width=8 seqs=43 chr10:76842639-76842719 ( 42) CAGTGAGA 1 chr22:21913507-21913587 ( 70) CAGTGAGC 1 chr2:100116290-100116370 ( 22) CAGAGAGA 1 chr16:24541168-24541248 ( 16) CAGTGAGC 1 chr22:22362796-22362876 ( 73) CAGTGAGC 1 chr1:145080541-145080621 ( 27) CAGTGAGC 1 chr7:73858766-73858846 ( 55) CAGAGAGA 1 chr6:130504905-130504985 ( 20) CAGAGAGA 1 chr7:151080882-151080962 ( 52) CAGTGAGC 1 chr7:138995401-138995481 ( 58) CAGTGAGC 1 chr7:139889609-139889689 ( 11) CAGTGAGC 1 chr21:33769146-33769226 ( 31) CAGTGAGC 1 chr11:108508187-10850826 ( 72) CAGGGAGA 1 chr22:22097940-22098020 ( 12) CAGGGAGA 1 chr7:143046983-143047063 ( 35) CAGGGAGA 1 chr22:21053237-21053317 ( 68) CAGGGAGA 1 chr16:31109757-31109837 ( 2) CAGAGAGC 1 chr6:35756501-35756581 ( 1) GAGTGAGA 1 chr22:23423970-23424050 ( 21) GAGTGAGA 1 chr22:23159043-23159123 ( 13) GAGTGAGA 1 chr2:149365343-149365423 ( 55) CAGGGAGC 1 chr22:22569614-22569694 ( 71) AAGTGAGA 1 chr15:79329093-79329173 ( 11) GAGAGAGA 1 chr10:47014275-47014355 ( 45) GAGAGAGA 1 chr1:48080800-48080880 ( 5) GAGAGAGA 1 chr1:180569496-180569576 ( 44) GAGAGAGA 1 chr17:28799748-28799828 ( 1) GAGTGAGC 1 chr22:23141231-23141311 ( 16) AAGTGAGA 1 chr9:140811202-140811282 ( 47) GAGGGAGA 1 chr22:21387233-21387313 ( 2) CAGTGAGT 1 chr12:101917302-10191738 ( 58) CAGTGAGT 1 chr13:91796467-91796547 ( 38) CAGTGACA 1 chr21:46968182-46968262 ( 46) CAGTGACA 1 chr22:22732891-22732971 ( 38) AAGAGAGA 1 chr6:6700019-6700099 ( 29) AAGGGAGA 1 chr21:46965536-46965616 ( 55) CAGAGACA 1 chr22:23002482-23002562 ( 63) CAGAGAGT 1 chr3:14376240-14376320 ( 16) CAGAGACA 1 chr7:158517360-158517440 ( 73) CAGAGAGT 1 chr7:150059078-150059158 ( 62) AAGGGAGC 1 chr8:2272284-2272364 ( 41) AAGGGAGC 1 chr5:71186298-71186378 ( 10) GAGTGACA 1 chr22:23165343-23165423 ( 42) CAGGGACC 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CAGDGAGM MEME-4 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 10.2475 E= 9.7e+001 -88 138 -11 -1207 196 -1207 -1207 -1207 -1207 -1207 200 -1207 23 -1207 -11 89 -1207 -1207 200 -1207 196 -1207 -1207 -1207 -1207 -79 178 -1207 118 43 -1207 -143 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CAGDGAGM MEME-4 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 43 E= 9.7e+001 0.139535 0.627907 0.232558 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.302326 0.000000 0.232558 0.465116 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.139535 0.860465 0.000000 0.581395 0.325581 0.000000 0.093023 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CAGDGAGM MEME-4 regular expression -------------------------------------------------------------------------------- [CG]AG[TAG]GAG[AC] -------------------------------------------------------------------------------- Time 15.96 secs. ******************************************************************************** ******************************************************************************** MOTIF CTCWCTGY MEME-5 width = 8 sites = 20 llr = 185 E-value = 9.0e+000 ******************************************************************************** -------------------------------------------------------------------------------- Motif CTCWCTGY MEME-5 Description -------------------------------------------------------------------------------- Simplified A :::4:::1 pos.-specific C a:a2a::6 probability G ::::::a: matrix T :a:5:a:3 bits 2.1 *** *** 1.8 *** *** 1.6 *** *** 1.4 *** *** Relative 1.2 *** *** Entropy 1.0 *** *** (13.4 bits) 0.8 *** **** 0.6 *** **** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel CTCTCTGC consensus A T sequence C -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTCWCTGY MEME-5 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr7:117612058-117612138 36 1.34e-05 tcaatctcgg ctctctgc aacctctgcc chr22:21018983-21019063 52 1.34e-05 gacacattgt ctctctgc actgcctggg chr13:90661321-90661401 72 1.34e-05 AAAGATGCCA CTCTCTGC T chr2:149553883-149553963 1 2.71e-05 . ctcactgc ctttgtatgt chr22:23361658-23361738 24 2.71e-05 gcctaaaggg ctcactgc agcctcgaac chr7:155389832-155389912 9 2.71e-05 gatctcgg ctcactgc aacctctgcc chr12:62821411-62821491 37 2.71e-05 gccatcttgg ctcactgc aacctctact chr22:22693329-22693409 13 2.71e-05 acaatcttgg ctcactgc aacctctgcc chr22:23287573-23287653 42 2.71e-05 acagttttgg ctcactgc tgcctcaaat chr5:110103997-110104077 26 2.71e-05 tctgactact ctcactgc tgccctacat chr2:91778050-91778130 12 4.10e-05 CTGCCTTGGT CTCTCTGT GCATCTTTCC chr1:4188372-4188452 64 4.10e-05 gtgtgtctcc ctctctgt gggtctctc chr19:54387130-54387210 45 4.10e-05 tgctctgtgt ctctctgt aagtctctgc chr22:22410142-22410222 41 4.10e-05 ctttgtggtg ctctctgt atttcctgaa chr12:94930056-94930136 5 5.39e-05 ccct ctccctgc ttcagccgca chr10:47084373-47084453 63 5.39e-05 cttctctcac ctccctgc tccctgctcc chr7:138711875-138711955 33 8.16e-05 ATGCAGAGCC CTCCCTGT CTGCACTCAC chr9:125101388-125101468 29 8.16e-05 cttcccttgc ctccctgt ccatctcctc chr1:206285175-206285255 56 9.58e-05 tttaactggg ctctctga caccgggagg chr5:12113-12193 11 9.58e-05 cttctaactg ctctctga ccttgattat -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTCWCTGY MEME-5 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr7:117612058-117612138 1.3e-05 35_[+5]_37 chr22:21018983-21019063 1.3e-05 51_[+5]_21 chr13:90661321-90661401 1.3e-05 71_[+5]_1 chr2:149553883-149553963 2.7e-05 [+5]_72 chr22:23361658-23361738 2.7e-05 23_[+5]_49 chr7:155389832-155389912 2.7e-05 8_[+5]_64 chr12:62821411-62821491 2.7e-05 36_[+5]_36 chr22:22693329-22693409 2.7e-05 12_[+5]_60 chr22:23287573-23287653 2.7e-05 41_[+5]_31 chr5:110103997-110104077 2.7e-05 25_[+5]_47 chr2:91778050-91778130 4.1e-05 11_[+5]_61 chr1:4188372-4188452 4.1e-05 63_[+5]_9 chr19:54387130-54387210 4.1e-05 44_[+5]_28 chr22:22410142-22410222 4.1e-05 40_[+5]_32 chr12:94930056-94930136 5.4e-05 4_[+5]_68 chr10:47084373-47084453 5.4e-05 62_[+5]_10 chr7:138711875-138711955 8.2e-05 32_[+5]_40 chr9:125101388-125101468 8.2e-05 28_[+5]_44 chr1:206285175-206285255 9.6e-05 55_[+5]_17 chr5:12113-12193 9.6e-05 10_[+5]_62 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTCWCTGY MEME-5 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF CTCWCTGY width=8 seqs=20 chr7:117612058-117612138 ( 36) CTCTCTGC 1 chr22:21018983-21019063 ( 52) CTCTCTGC 1 chr13:90661321-90661401 ( 72) CTCTCTGC 1 chr2:149553883-149553963 ( 1) CTCACTGC 1 chr22:23361658-23361738 ( 24) CTCACTGC 1 chr7:155389832-155389912 ( 9) CTCACTGC 1 chr12:62821411-62821491 ( 37) CTCACTGC 1 chr22:22693329-22693409 ( 13) CTCACTGC 1 chr22:23287573-23287653 ( 42) CTCACTGC 1 chr5:110103997-110104077 ( 26) CTCACTGC 1 chr2:91778050-91778130 ( 12) CTCTCTGT 1 chr1:4188372-4188452 ( 64) CTCTCTGT 1 chr19:54387130-54387210 ( 45) CTCTCTGT 1 chr22:22410142-22410222 ( 41) CTCTCTGT 1 chr12:94930056-94930136 ( 5) CTCCCTGC 1 chr10:47084373-47084453 ( 63) CTCCCTGC 1 chr7:138711875-138711955 ( 33) CTCCCTGT 1 chr9:125101388-125101468 ( 29) CTCCCTGT 1 chr1:206285175-206285255 ( 56) CTCTCTGA 1 chr5:12113-12193 ( 11) CTCTCTGA 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTCWCTGY MEME-5 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 10.7763 E= 9.0e+000 -1097 205 -1097 -1097 -1097 -1097 -1097 200 -1097 205 -1097 -1097 44 -27 -1097 84 -1097 205 -1097 -1097 -1097 -1097 -1097 200 -1097 -1097 200 -1097 -136 131 -1097 26 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTCWCTGY MEME-5 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 20 E= 9.0e+000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 0.350000 0.200000 0.000000 0.450000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.100000 0.600000 0.000000 0.300000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTCWCTGY MEME-5 regular expression -------------------------------------------------------------------------------- CTC[TAC]CTG[CT] -------------------------------------------------------------------------------- Time 19.44 secs. ******************************************************************************** ******************************************************************************** SUMMARY OF MOTIFS ******************************************************************************** -------------------------------------------------------------------------------- Combined block diagrams: non-overlapping sites with p-value < 0.0001 -------------------------------------------------------------------------------- SEQUENCE NAME COMBINED P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr22:20948959-20949039 1.64e-01 80 chr22:23439522-23439602 2.48e-02 80 chr22:23165343-23165423 4.75e-03 80 chr22:17197483-17197563 2.66e-01 80 chr22:23100767-23100847 4.08e-01 80 chr22:19612681-19612761 5.26e-01 80 chr16:85052817-85052897 2.49e-01 80 chr21:33769146-33769226 1.98e-05 16_[+3(1.59e-05)]_6_[+4(4.81e-05)]_\ 19_[+2(1.37e-05)]_15 chr22:22732891-22732971 2.03e-02 80 chr1:172584831-172584911 8.21e-01 80 chr7:111208624-111208704 5.94e-01 80 chr2:169134657-169134737 6.74e-01 80 chr22:23159043-23159123 1.50e-02 12_[+4(9.68e-05)]_60 chr13:90503975-90504055 4.35e-03 62_[+1(4.07e-05)]_[+2(5.45e-05)]_2 chr19:54929563-54929643 1.33e-04 11_[+1(1.34e-05)]_61 chr13:92270043-92270123 7.17e-02 26_[+2(5.45e-05)]_46 chr5:110103997-110104077 6.96e-05 4_[+2(2.69e-05)]_13_[+5(2.71e-05)]_\ 47 chr7:137690841-137690921 2.23e-04 57_[+1(1.34e-05)]_15 chr22:22077702-22077782 2.94e-04 36_[+1(1.34e-05)]_18_[+2(4.03e-05)]_\ 10 chr10:47015549-47015629 2.06e-02 80 chr21:46968182-46968262 6.14e-02 80 chr6:6721141-6721221 1.59e-01 80 chr13:92231711-92231791 4.27e-02 80 chr2:174859491-174859571 2.64e-01 80 chr8:12404300-12404380 2.08e-02 80 chr1:29464626-29464706 2.56e-02 5_[+2(1.37e-05)]_67 chr22:20175758-20175838 1.09e-02 80 chr10:59946741-59946821 2.41e-02 9_[+3(3.13e-05)]_63 chr22:21053237-21053317 5.72e-03 67_[+4(6.43e-05)]_5 chr9:125101388-125101468 3.04e-02 28_[+5(8.16e-05)]_44 chr7:127754091-127754171 6.00e-02 80 chr6:140152670-140152750 8.65e-01 80 chr13:92309314-92309394 9.69e-01 80 chr19:8197792-8197872 6.93e-04 3_[+1(2.68e-05)]_53_[+2(5.45e-05)]_\ 8 chr13:90661321-90661401 5.04e-02 71_[+5(1.34e-05)]_1 chr3:46041236-46041316 2.62e-01 80 chr22:23502597-23502677 6.40e-03 80 chr17:56763701-56763781 4.40e-02 39_[+3(1.59e-05)]_33 chr22:22761549-22761629 1.17e-02 80 chr13:81462934-81463014 1.76e-01 80 chr22:22506189-22506269 9.98e-01 80 chr7:139889609-139889689 9.62e-06 10_[+4(4.81e-05)]_19_[+2(1.37e-05)]_\ 16_[+1(4.07e-05)]_11 chr7:138995401-138995481 3.16e-03 43_[+3(1.59e-05)]_6_[+4(4.81e-05)]_\ 15 chr7:151080882-151080962 7.01e-03 51_[+4(4.81e-05)]_21 chr21:33947463-33947543 5.83e-02 80 chr22:20787297-20787377 7.42e-01 80 chr6:130504905-130504985 2.82e-02 19_[+4(4.81e-05)]_35_[+4(4.81e-05)]_\ 10 chr2:157267821-157267901 6.80e-02 46_[+2(8.11e-05)]_26 chr10:76842639-76842719 1.92e-04 [+4(4.81e-05)]_19_[+2(1.37e-05)]_6_\ [+4(1.62e-05)]_31 chr17:28428985-28429065 2.18e-02 14_[+1(8.21e-05)]_58 chr22:23004569-23004649 3.20e-03 58_[+1(2.68e-05)]_14 chr2:25155761-25155841 6.40e-01 80 chr6:38684164-38684244 1.40e-02 80 chr2:91764658-91764738 1.93e-01 80 chr7:73858766-73858846 1.29e-01 23_[+4(7.99e-05)]_23_[+4(4.81e-05)]_\ 18 chr22:23423970-23424050 2.33e-03 4_[+2(1.37e-05)]_8_[+4(9.68e-05)]_\ 52 chr22:21330736-21330816 1.39e-01 40_[+3(9.53e-05)]_32 chr22:23287573-23287653 1.25e-04 10_[+2(8.11e-05)]_23_[+5(2.71e-05)]_\ 31 chr7:143098688-143098768 6.36e-02 80 chr1:17024028-17024108 1.07e-01 80 chr22:21018983-21019063 9.34e-05 51_[+5(1.34e-05)]_21 chr22:22751695-22751775 4.84e-02 80 chr1:40600459-40600539 1.05e-01 59_[+1(2.68e-05)]_13 chr12:71671427-71671507 7.90e-01 80 chr22:22424989-22425069 3.42e-01 80 chr22:22410142-22410222 3.88e-03 40_[+5(4.10e-05)]_32 chr22:23165927-23166007 8.46e-01 80 chr1:192252891-192252971 6.92e-02 80 chr13:92382259-92382339 3.01e-02 39_[+2(9.51e-05)]_33 chr6:31682144-31682224 2.39e-02 80 chr2:91770643-91770723 6.10e-01 80 chr22:23135412-23135492 1.80e-04 21_[+2(5.45e-05)]_5_[+3(9.53e-05)]_\ 38 chr22:23118883-23118963 3.81e-01 80 chr22:23454818-23454898 6.70e-01 80 chr7:138137973-138138053 1.22e-01 80 chr1:162460781-162460861 3.94e-02 80 chr13:91796467-91796547 1.71e-01 80 chr22:23141231-23141311 8.20e-02 80 chr12:101917302-10191738 1.49e-02 11_[+3(3.13e-05)]_61 chr1:145080541-145080621 3.94e-04 12_[+3(1.59e-05)]_6_[+4(4.81e-05)]_\ 46 chr1:31107202-31107282 1.97e-01 80 chrX:9379883-9379963 3.62e-01 80 chr17:28799748-28799828 9.50e-03 37_[+3(6.37e-05)]_35 chr22:22390362-22390442 1.02e-01 80 chr22:22362796-22362876 1.34e-03 26_[+3(3.13e-05)]_24_[+3(1.59e-05)]_\ 6_[+4(4.81e-05)] chr22:21329431-21329511 2.72e-01 80 chr22:22382974-22383054 1.19e-01 80 chr22:23214811-23214891 6.29e-01 80 chr1:180569496-180569576 8.36e-02 80 chr13:92450109-92450189 7.12e-01 80 chr10:47084373-47084453 5.48e-03 62_[+5(5.39e-05)]_10 chr7:158517360-158517440 1.84e-02 40_[+3(9.53e-05)]_32 chr21:46967451-46967531 3.18e-01 80 chr5:12113-12193 1.45e-01 10_[+5(9.58e-05)]_62 chr6:36279100-36279180 7.37e-02 80 chr12:66658469-66658549 5.98e-01 80 chr6:39828348-39828428 4.58e-01 80 chr22:22520868-22520948 4.42e-03 80 chr1:32202868-32202948 9.07e-01 80 chr22:22693329-22693409 8.11e-05 12_[+5(2.71e-05)]_3_[+1(1.34e-05)]_\ 24_[+1(8.21e-05)]_17 chr17:27042735-27042815 7.88e-01 80 chr3:150789702-150789782 1.00e+00 80 chr19:54387130-54387210 2.38e-02 44_[+5(4.10e-05)]_28 chr1:48080800-48080880 7.13e-02 80 chr18:3294508-3294588 4.04e-01 80 chr1:101212056-101212136 1.66e-01 57_[+3(6.37e-05)]_15 chr22:23381775-23381855 1.83e-02 80 chr2:169841634-169841714 7.14e-01 80 chr22:23451098-23451178 1.90e-01 80 chr1:4188372-4188452 2.88e-04 33_[+1(1.34e-05)]_22_[+5(4.10e-05)]_\ 9 chr22:22471940-22472020 7.03e-02 80 chr22:22564256-22564336 9.66e-03 80 chr18:9326197-9326277 1.18e-01 80 chr22:20723811-20723891 2.04e-02 80 chr1:17040147-17040227 1.11e-02 80 chr3:14376240-14376320 1.47e-01 80 chr15:45081092-45081172 3.07e-01 80 chr22:23280898-23280978 9.16e-03 68_[+2(4.03e-05)]_4 chr19:16217266-16217346 6.62e-02 80 chr13:91946847-91946927 1.53e-01 80 chr12:62821411-62821491 2.15e-02 36_[+5(2.71e-05)]_36 chr6:112430584-112430664 2.65e-02 80 chr10:46955145-46955225 8.50e-01 80 chr13:91717001-91717081 2.47e-02 44_[+4(9.68e-05)]_28 chr1:20255665-20255745 8.76e-01 80 chr22:22426591-22426671 4.65e-04 29_[+1(1.34e-05)]_43 chr6:29527886-29527966 7.89e-05 22_[+5(1.34e-05)]_50 chr6:27590800-27590880 4.36e-01 80 chr7:155389832-155389912 4.78e-05 8_[+5(2.71e-05)]_3_[+1(1.34e-05)]_\ 24_[+1(8.21e-05)]_21 chr8:2272284-2272364 4.75e-02 80 chr7:150846871-150846951 1.95e-02 80 chr22:22434558-22434638 5.96e-03 37_[+3(9.53e-05)]_35 chr11:34453438-34453518 2.15e-04 69_[+1(1.34e-05)]_3 chr22:23329940-23330020 4.81e-01 80 chr22:19138611-19138691 4.20e-02 80 chr2:149365343-149365423 7.54e-02 80 chr13:91039741-91039821 8.79e-01 80 chr3:170402799-170402879 1.62e-01 80 chr22:23158413-23158493 4.22e-03 30_[+1(2.68e-05)]_20_[+1(8.21e-05)]_\ 14 chr5:71186298-71186378 1.09e-02 67_[+3(9.53e-05)]_5 chr22:20282423-20282503 7.42e-01 80 chr13:91456631-91456711 3.92e-01 80 chr7:121063038-121063118 8.02e-01 80 chr15:39803446-39803526 1.66e-01 38_[+3(6.37e-05)]_34 chr22:23327020-23327100 1.25e-02 30_[+3(6.37e-05)]_42 chr22:18977937-18978017 5.49e-01 80 chr22:23380507-23380587 2.08e-01 35_[+3(9.53e-05)]_37 chr22:23002482-23002562 1.13e-01 80 chr1:37228236-37228316 3.26e-01 80 chr22:23235421-23235501 4.31e-01 80 chr1:197835621-197835701 1.08e-02 33_[+3(6.37e-05)]_18_[+3(1.59e-05)]_\ 13 chr7:112768562-112768642 7.17e-01 80 chr22:23140251-23140331 5.87e-01 80 chr6:11398123-11398203 3.68e-01 80 chr22:20294231-20294311 4.89e-01 80 chr16:24541168-24541248 9.33e-05 15_[+4(4.81e-05)]_19_[+2(1.37e-05)]_\ 30 chr7:92179406-92179486 2.62e-01 80 chr21:44368757-44368837 1.32e-04 [+1(8.21e-05)]_26_[+1(8.21e-05)]_20_\ [+1(2.68e-05)]_2_[+1(1.34e-05)] chr12:131733822-13173390 9.60e-01 80 chr13:81310125-81310205 2.22e-03 25_[+1(8.21e-05)]_31_[+2(5.45e-05)]_\ 8 chr22:23361658-23361738 4.21e-04 23_[+5(2.71e-05)]_35_[+1(8.21e-05)]_\ 6 chr7:130822322-130822402 5.10e-01 80 chr1:227746872-227746952 5.74e-02 33_[+1(8.21e-05)]_22_[+1(8.21e-05)]_\ 9 chr3:41287641-41287721 2.20e-01 80 chr10:47133578-47133658 9.89e-01 80 chr8:103032982-103033062 7.65e-02 80 chr21:46965536-46965616 4.22e-01 80 chr7:111361125-111361205 8.42e-01 80 chr1:1520586-1520666 1.05e-02 20_[+2(4.03e-05)]_52 chr22:22504504-22504584 9.39e-02 80 chr1:110284530-110284610 1.82e-01 80 chr13:92401126-92401206 8.14e-01 80 chr22:21387233-21387313 1.25e-02 80 chr6:111192713-111192793 9.75e-01 80 chr7:152434122-152434202 2.68e-04 11_[+1(1.34e-05)]_18_[+2(4.03e-05)]_\ 35 chr17:63123766-63123846 9.74e-02 80 chr7:143046983-143047063 7.99e-02 34_[+4(6.43e-05)]_38 chr1:225705518-225705598 6.44e-01 80 chr22:22097940-22098020 1.50e-02 11_[+4(6.43e-05)]_17_[+4(6.43e-05)]_\ 36 chr1:116621631-116621711 2.87e-01 80 chr19:51311654-51311734 1.81e-01 80 chr15:20501658-20501738 8.45e-01 80 chr6:39268581-39268661 3.29e-02 80 chr1:3676822-3676902 8.91e-02 80 chr11:56981520-56981600 6.57e-01 80 chr2:91778050-91778130 1.01e-02 11_[+5(4.10e-05)]_51_[+5(9.58e-05)]_\ 2 chr22:21419607-21419687 8.80e-02 80 chr2:149553883-149553963 1.42e-02 [+5(2.71e-05)]_72 chr13:91768175-91768255 1.13e-01 80 chr22:23017208-23017288 3.13e-01 80 chr13:91489048-91489128 6.03e-03 32_[+2(4.03e-05)]_40 chr22:23261312-23261392 2.87e-01 80 chr13:90662359-90662439 8.60e-01 80 chr21:43812448-43812528 7.89e-02 68_[+3(3.13e-05)]_4 chr2:55925975-55926055 1.60e-01 80 chr7:150059078-150059158 3.12e-01 80 chr22:19757333-19757413 8.53e-03 20_[+2(1.37e-05)]_52 chr22:23242764-23242844 3.12e-02 80 chr13:90946173-90946253 8.77e-02 80 chr22:23081571-23081651 4.17e-03 80 chr22:23372984-23373064 8.37e-01 80 chr15:20864827-20864907 1.86e-02 55_[+3(3.13e-05)]_17 chr17:74006031-74006111 1.06e-01 80 chr17:44328239-44328319 6.90e-03 4_[+1(2.68e-05)]_1_[+1(2.68e-05)]_4_\ [+1(2.68e-05)]_7_[+1(2.68e-05)]_32 chr16:31109757-31109837 5.93e-03 1_[+4(7.99e-05)]_71 chr22:17008725-17008805 3.79e-03 14_[+1(8.21e-05)]_14_[+1(1.34e-05)]_\ 36 chr1:223413749-223413829 9.84e-01 80 chr10:47014275-47014355 2.15e-02 29_[+4(4.81e-05)]_43 chr22:23463992-23464072 8.42e-03 30_[+2(2.69e-05)]_42 chr16:33418464-33418544 1.17e-02 80 chr13:81457347-81457427 2.21e-01 80 chr6:170725382-170725462 5.17e-01 80 chr2:100116290-100116370 3.70e-02 21_[+4(4.81e-05)]_22_[+4(4.81e-05)]_\ 21 chr13:91561196-91561276 8.58e-01 80 chr1:22141659-22141739 3.52e-01 80 chr22:22365170-22365250 4.95e-03 80 chr12:94930056-94930136 1.08e-03 4_[+5(5.39e-05)]_22_[+1(2.68e-05)]_\ 38 chr22:23468704-23468784 1.96e-01 80 chr11:108508187-10850826 1.38e-01 71_[+4(6.43e-05)]_1 chr2:183940950-183941030 4.71e-01 80 chr15:79329093-79329173 3.30e-02 57_[+3(6.37e-05)]_15 chr7:100643412-100643492 3.04e-02 16_[+2(8.11e-05)]_56 chr22:23378980-23379060 1.58e-04 80 chr6:7322162-7322242 8.13e-01 80 chr7:138711875-138711955 2.30e-02 32_[+5(8.16e-05)]_40 chr22:21248925-21249005 6.31e-01 80 chr7:116073060-116073140 1.25e-02 80 chr13:90655944-90656024 1.39e-02 80 chr22:20955517-20955597 6.64e-03 65_[+2(4.03e-05)]_7 chr7:117612058-117612138 1.64e-05 4_[+2(8.11e-05)]_23_[+5(1.34e-05)]_\ 3_[+1(1.34e-05)]_18_[+2(4.03e-05)] chr13:81256343-81256423 5.77e-04 17_[+1(1.34e-05)]_55 chr22:22756009-22756089 6.46e-02 80 chr22:23469436-23469516 9.22e-02 80 chr1:234455956-234456036 2.36e-01 80 chr22:23418194-23418274 2.05e-03 61_[+3(3.13e-05)]_11 chr7:140116339-140116419 4.04e-02 80 chr22:23271913-23271993 4.75e-01 80 chr22:22569614-22569694 2.96e-03 80 chr1:22372037-22372117 7.67e-01 80 chr12:93859051-93859131 1.53e-01 80 chr1:206285175-206285255 3.20e-03 55_[+5(9.58e-05)]_17 chr9:140811202-140811282 2.86e-02 80 chr7:139915101-139915181 9.89e-02 80 chr1:12606621-12606701 8.66e-03 80 chr22:23465394-23465474 1.57e-01 80 chr6:35756501-35756581 6.41e-02 [+4(9.68e-05)]_72 chr9:95566952-95567032 9.48e-01 80 chr22:23336245-23336325 5.00e-01 80 chr22:21913507-21913587 7.75e-04 23_[+3(3.13e-05)]_38_[+4(4.81e-05)]_\ 3 chr6:6700019-6700099 2.00e-01 80 -------------------------------------------------------------------------------- ******************************************************************************** ******************************************************************************** Stopped because requested number of motifs (5) found. ******************************************************************************** CPU: c22n04.farnam.hpc.yale.internal ********************************************************************************