******************************************************************************** MEME - Motif discovery tool ******************************************************************************** MEME version 5.3.3 (Release date: Sun Feb 7 15:39:52 2021 -0800) For further information on how to interpret these results please access https://meme-suite.org/meme. To get a copy of the MEME Suite software please access https://meme-suite.org. ******************************************************************************** ******************************************************************************** REFERENCE ******************************************************************************** If you use this program in your research, please cite: Timothy L. Bailey and Charles Elkan, "Fitting a mixture model by expectation maximization to discover motifs in biopolymers", Proceedings of the Second International Conference on Intelligent Systems for Molecular Biology, pp. 28-36, AAAI Press, Menlo Park, California, 1994. ******************************************************************************** ******************************************************************************** TRAINING SET ******************************************************************************** PRIMARY SEQUENCES= ../result/final_prediction/K562/fasta/RankLinear0.6_40/MCM2.fasta CONTROL SEQUENCES= --none-- ALPHABET= ACGT Sequence name Weight Length Sequence name Weight Length ------------- ------ ------ ------------- ------ ------ chr22:22479813-22479893 1.0000 80 chr13:91972286-91972366 1.0000 80 chr13:81233439-81233519 1.0000 80 chr13:92290626-92290706 1.0000 80 chr13:90721789-90721869 1.0000 80 chr13:91945665-91945745 1.0000 80 chr7:54613831-54613911 1.0000 80 chr13:90902075-90902155 1.0000 80 chr3:39237615-39237695 1.0000 80 chr4:126236244-126236324 1.0000 80 chr22:23373442-23373522 1.0000 80 chr16:21312734-21312814 1.0000 80 chr13:91743930-91744010 1.0000 80 chr7:155585830-155585910 1.0000 80 chr13:92359776-92359856 1.0000 80 chr5:38348532-38348612 1.0000 80 chr15:26003844-26003924 1.0000 80 chr7:154570414-154570494 1.0000 80 chr8:58122681-58122761 1.0000 80 chr13:91863940-91864020 1.0000 80 chr13:91123997-91124077 1.0000 80 chr13:91345043-91345123 1.0000 80 chr5:2593416-2593496 1.0000 80 chr7:121575526-121575606 1.0000 80 chr13:91838901-91838981 1.0000 80 chr13:91352150-91352230 1.0000 80 chr13:91405545-91405625 1.0000 80 chr22:23287539-23287619 1.0000 80 chr13:91078714-91078794 1.0000 80 chr22:23118895-23118975 1.0000 80 chr6:142959964-142960044 1.0000 80 chr21:11138816-11138896 1.0000 80 chr7:152995015-152995095 1.0000 80 chr13:81188979-81189059 1.0000 80 chr22:23140410-23140490 1.0000 80 chr10:52014963-52015043 1.0000 80 chr5:16574376-16574456 1.0000 80 chr7:131195783-131195863 1.0000 80 chr13:90870841-90870921 1.0000 80 chr1:142967250-142967330 1.0000 80 chr13:92349459-92349539 1.0000 80 chr13:91843359-91843439 1.0000 80 chr13:81414872-81414952 1.0000 80 chr6:166121139-166121219 1.0000 80 chr10:47039406-47039486 1.0000 80 chr22:16918392-16918472 1.0000 80 chr22:17064444-17064524 1.0000 80 chr6:133089425-133089505 1.0000 80 chr11:66316453-66316533 1.0000 80 chr11:129718332-12971841 1.0000 80 chr22:23456195-23456275 1.0000 80 chr6:50654306-50654386 1.0000 80 chr13:92241524-92241604 1.0000 80 chr1:172632753-172632833 1.0000 80 chr22:23381709-23381789 1.0000 80 chr13:91489983-91490063 1.0000 80 chr22:17076162-17076242 1.0000 80 chr12:130498510-13049859 1.0000 80 chr13:91006720-91006800 1.0000 80 chr1:185634126-185634206 1.0000 80 chr13:91916792-91916872 1.0000 80 chr13:92402145-92402225 1.0000 80 chr21:11066751-11066831 1.0000 80 chr10:44738462-44738542 1.0000 80 chr22:20946792-20946872 1.0000 80 chr13:81310114-81310194 1.0000 80 chr22:29600971-29601051 1.0000 80 chr22:23380440-23380520 1.0000 80 chr13:91261538-91261618 1.0000 80 chr7:144101420-144101500 1.0000 80 chr6:6522486-6522566 1.0000 80 chr16:74407456-74407536 1.0000 80 chr10:85631393-85631473 1.0000 80 chr2:105495453-105495533 1.0000 80 chr13:91946610-91946690 1.0000 80 chr13:81234172-81234252 1.0000 80 chr22:17024704-17024784 1.0000 80 chr22:17038777-17038857 1.0000 80 chr22:23231144-23231224 1.0000 80 chr13:114489366-11448944 1.0000 80 chr2:30099393-30099473 1.0000 80 chr22:21416520-21416600 1.0000 80 chr22:23223472-23223552 1.0000 80 chr13:92317854-92317934 1.0000 80 chr8:48116032-48116112 1.0000 80 chr4:190527771-190527851 1.0000 80 chr22:23137420-23137500 1.0000 80 chr7:141783521-141783601 1.0000 80 chr1:21835506-21835586 1.0000 80 chr13:92435779-92435859 1.0000 80 chr13:91202375-91202455 1.0000 80 chr2:53110099-53110179 1.0000 80 chr7:158309269-158309349 1.0000 80 chr5:6797628-6797708 1.0000 80 chr16:26553640-26553720 1.0000 80 chr5:142716-142796 1.0000 80 chr11:287643-287723 1.0000 80 chr10:47124715-47124795 1.0000 80 chr7:159087368-159087448 1.0000 80 chr22:23279632-23279712 1.0000 80 chr13:91897778-91897858 1.0000 80 chr13:91410955-91411035 1.0000 80 chr15:20864817-20864897 1.0000 80 chr13:90655953-90656033 1.0000 80 chr21:10139959-10140039 1.0000 80 chr13:92946935-92947015 1.0000 80 chr13:92084394-92084474 1.0000 80 chr6:11427602-11427682 1.0000 80 chr2:91778041-91778121 1.0000 80 chr8:144492720-144492800 1.0000 80 chr10:47014217-47014297 1.0000 80 chr13:92360445-92360525 1.0000 80 chr18:22962685-22962765 1.0000 80 chr7:126899568-126899648 1.0000 80 chr10:47092840-47092920 1.0000 80 chr22:21911833-21911913 1.0000 80 chr12:42418113-42418193 1.0000 80 chr13:91002487-91002567 1.0000 80 chr22:23379752-23379832 1.0000 80 chr6:41613403-41613483 1.0000 80 chr13:92365158-92365238 1.0000 80 chr6:141494261-141494341 1.0000 80 chr13:92314455-92314535 1.0000 80 chr13:81268515-81268595 1.0000 80 chr13:92373444-92373524 1.0000 80 chr7:154140678-154140758 1.0000 80 chr22:23405668-23405748 1.0000 80 chr13:81371796-81371876 1.0000 80 chr22:23101566-23101646 1.0000 80 chr13:90561372-90561452 1.0000 80 chr22:16984493-16984573 1.0000 80 chr10:35992934-35993014 1.0000 80 chr22:23000045-23000125 1.0000 80 chr11:132409713-13240979 1.0000 80 chr22:17002798-17002878 1.0000 80 chr13:81369545-81369625 1.0000 80 chr13:91635305-91635385 1.0000 80 chr7:112057278-112057358 1.0000 80 chr5:33672175-33672255 1.0000 80 chr13:91393563-91393643 1.0000 80 chr13:90595462-90595542 1.0000 80 chr3:25627578-25627658 1.0000 80 chr12:129873946-12987402 1.0000 80 chr1:236156693-236156773 1.0000 80 chr13:91887096-91887176 1.0000 80 chr13:91522042-91522122 1.0000 80 chr13:91315407-91315487 1.0000 80 chr22:23465430-23465510 1.0000 80 chr7:87860120-87860200 1.0000 80 chr7:68489467-68489547 1.0000 80 chr22:23107497-23107577 1.0000 80 chr11:3458817-3458897 1.0000 80 chr5:17146725-17146805 1.0000 80 chr14:19613018-19613098 1.0000 80 chr2:149859077-149859157 1.0000 80 chr3:13789228-13789308 1.0000 80 chr13:92129950-92130030 1.0000 80 chr7:98375324-98375404 1.0000 80 chr9:66455314-66455394 1.0000 80 chr7:56395185-56395265 1.0000 80 chr22:23354310-23354390 1.0000 80 chr1:27963210-27963290 1.0000 80 chr10:84220969-84221049 1.0000 80 chr8:14718003-14718083 1.0000 80 chr7:136575606-136575686 1.0000 80 chr17:41465264-41465344 1.0000 80 chr18:56449061-56449141 1.0000 80 chr10:17055274-17055354 1.0000 80 chr7:134415857-134415937 1.0000 80 chr7:111397014-111397094 1.0000 80 chr21:34563697-34563777 1.0000 80 chr13:91546393-91546473 1.0000 80 chr7:156241768-156241848 1.0000 80 chr13:91594632-91594712 1.0000 80 chr7:148028688-148028768 1.0000 80 chr21:44919729-44919809 1.0000 80 chr16:4261625-4261705 1.0000 80 chr2:149877635-149877715 1.0000 80 chr4:178171342-178171422 1.0000 80 chr22:23117322-23117402 1.0000 80 chr11:65669778-65669858 1.0000 80 chr1:209313371-209313451 1.0000 80 chr15:20545090-20545170 1.0000 80 chr22:23423154-23423234 1.0000 80 chr21:11110658-11110738 1.0000 80 chr22:22557749-22557829 1.0000 80 chr22:22795723-22795803 1.0000 80 chr5:131191272-131191352 1.0000 80 chr11:131893590-13189367 1.0000 80 chr2:91763990-91764070 1.0000 80 chr18:24229729-24229809 1.0000 80 chr6:41985719-41985799 1.0000 80 chr8:58118551-58118631 1.0000 80 chr1:175734657-175734737 1.0000 80 chr13:92370462-92370542 1.0000 80 chr16:5161130-5161210 1.0000 80 chr9:131006434-131006514 1.0000 80 chr10:59305406-59305486 1.0000 80 chr7:112337772-112337852 1.0000 80 chr22:23259758-23259838 1.0000 80 chr1:16484330-16484410 1.0000 80 chr13:91533260-91533340 1.0000 80 chr13:91358209-91358289 1.0000 80 chr1:209568841-209568921 1.0000 80 chr1:111264955-111265035 1.0000 80 chr2:91764649-91764729 1.0000 80 chr10:80664896-80664976 1.0000 80 chr18:23777285-23777365 1.0000 80 chr13:90986620-90986700 1.0000 80 chr1:228107442-228107522 1.0000 80 chr1:164444206-164444286 1.0000 80 chr4:3969101-3969181 1.0000 80 chr5:38290687-38290767 1.0000 80 chr7:152761637-152761717 1.0000 80 chr3:149939683-149939763 1.0000 80 chr22:22610615-22610695 1.0000 80 chr13:91831225-91831305 1.0000 80 chr1:17248230-17248310 1.0000 80 chr13:91148303-91148383 1.0000 80 chr13:81258728-81258808 1.0000 80 chr13:91139884-91139964 1.0000 80 chr6:99293753-99293833 1.0000 80 chr7:140861635-140861715 1.0000 80 chr16:49674216-49674296 1.0000 80 chr4:184277492-184277572 1.0000 80 chr15:22520730-22520810 1.0000 80 chr22:23375508-23375588 1.0000 80 chr6:21326072-21326152 1.0000 80 chr4:144860890-144860970 1.0000 80 chr22:23017159-23017239 1.0000 80 chr13:81413389-81413469 1.0000 80 chr20:43941974-43942054 1.0000 80 chr6:160956512-160956592 1.0000 80 chr21:40497777-40497857 1.0000 80 chr18:6042341-6042421 1.0000 80 chr13:90946140-90946220 1.0000 80 chr13:90914394-90914474 1.0000 80 chr22:23364716-23364796 1.0000 80 chr13:91914670-91914750 1.0000 80 chr6:21924989-21925069 1.0000 80 chr7:13199350-13199430 1.0000 80 chr22:23416798-23416878 1.0000 80 chr21:46313799-46313879 1.0000 80 chr22:23045675-23045755 1.0000 80 chr22:23440413-23440493 1.0000 80 chr1:19152331-19152411 1.0000 80 chr13:91825681-91825761 1.0000 80 chr22:17003686-17003766 1.0000 80 chr22:23458653-23458733 1.0000 80 chr5:168250272-168250352 1.0000 80 ******************************************************************************** ******************************************************************************** COMMAND LINE SUMMARY ******************************************************************************** This information can also be useful in the event you wish to report a problem with the MEME software. command: meme -oc ../result/final_prediction/K562/inference_raw/MEME/RankLinear0.6_40_MCM2/ -dna -nmotifs 5 -w 8 -maxsize 250000 -nostatus ../result/final_prediction/K562/fasta/RankLinear0.6_40/MCM2.fasta model: mod= zoops nmotifs= 5 evt= inf objective function: em= E-value of product of p-values starts= E-value of product of p-values strands: + width: minw= 8 maxw= 8 nsites: minsites= 2 maxsites= 250 wnsites= 0.8 theta: spmap= uni spfuzz= 0.5 em: prior= dirichlet b= 0.01 maxiter= 50 distance= 1e-05 trim: wg= 11 ws= 1 endgaps= yes data: n= 20000 N= 250 sample: seed= 0 hsfrac= 0 searchsize= 20000 norand= no csites= 1000 Letter frequencies in dataset: A 0.25 C 0.245 G 0.249 T 0.256 Background letter frequencies (from file dataset with add-one prior applied): A 0.25 C 0.245 G 0.249 T 0.256 Background model order: 0 ******************************************************************************** ******************************************************************************** MOTIF YCACTGCM MEME-1 width = 8 sites = 59 llr = 473 E-value = 8.2e-019 ******************************************************************************** -------------------------------------------------------------------------------- Motif YCACTGCM MEME-1 Description -------------------------------------------------------------------------------- Simplified A 1:7::::5 pos.-specific C 3a1a:2a5 probability G :::::8:: matrix T 6:2:a::: bits 2.0 * * * 1.8 * ** * 1.6 * ** * 1.4 * ** * Relative 1.2 * **** Entropy 1.0 * ***** (11.6 bits) 0.8 ******* 0.6 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel TCACTGCA consensus C T C sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YCACTGCM MEME-1 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr13:91831225-91831305 18 1.50e-05 caatcttggc tcactgca acctccgcct chr13:90986620-90986700 2 1.50e-05 c tcactgca acctctgcct chr2:149877635-149877715 14 1.50e-05 tgatctcggc tcactgca acctctgctt chr7:68489467-68489547 40 1.50e-05 tgatctcggc tcactgca acatctgcct chr13:91315407-91315487 19 1.50e-05 tgatcttggc tcactgca atctctgcct chr13:91393563-91393643 39 1.50e-05 caatctcggc tcactgca acctccacct chr22:16984493-16984573 9 1.50e-05 atctcagc tcactgca acctctgccc chr13:90561372-90561452 42 1.50e-05 cgatctcagc tcactgca accttcaact chr13:92373444-92373524 17 1.50e-05 caatctcagc tcactgca gcttccacct chr22:21911833-21911913 51 1.50e-05 caatcttggc tcactgca acctccgcct chr22:23137420-23137500 39 1.50e-05 caatctcagc tcactgca acctctgcct chr13:91946610-91946690 55 1.50e-05 tgatctcggc tcactgca acctccgcct chr13:91843359-91843439 60 1.50e-05 cgatctcggc tcactgca acctccgcct chr13:92349459-92349539 10 1.50e-05 gatctcggc tcactgca acctctacct chr13:81188979-81189059 13 1.50e-05 ctatctcagc tcactgca gcctgcgcct chr13:91345043-91345123 11 1.50e-05 cgatctcggc tcactgca agctccgtct chr13:91945665-91945745 21 1.50e-05 tgatctcggc tcactgca acctctgcct chr13:92290626-92290706 66 1.50e-05 tgacctcacc tcactgca aactctg chr6:21326072-21326152 71 2.97e-05 cgatctcagc tcactgcc ac chr12:129873946-12987402 62 2.97e-05 aacactaatg tcactgcc aacaccaaca chr13:91139884-91139964 53 4.41e-05 tgagatcaca ccactgca ctccagcctg chr13:91358209-91358289 51 4.41e-05 caagatcagg ccactgca ctccagcctg chr22:20946792-20946872 68 4.41e-05 agagatcgcg ccactgca ctcca chr21:11066751-11066831 27 4.41e-05 caagattgca ccactgca ctccagcctg chr13:92359776-92359856 57 4.41e-05 catgatcgcg ccactgca ctccagcttg chr13:91743930-91744010 34 4.41e-05 cgagatcttg ccactgca ctccagcctg chr1:19152331-19152411 7 5.81e-05 ctacta ccactgcc atcaacacta chr10:84220969-84221049 31 5.81e-05 accaccacca ccactgcc accaccacca chr10:80664896-80664976 6 8.85e-05 ctctc tctctgcc tccctctctc chr16:5161130-5161210 70 8.85e-05 AACTTCCTGT TCTCTGCC TCT chr11:3458817-3458897 48 8.85e-05 AACTTCCTCT TCTCTGCC TCTGGCCCGA chr13:91914670-91914750 65 1.32e-04 ttagtttagt tcactccc acttatct chr16:49674216-49674296 35 1.32e-04 attcacacca tcactccc acacactcac chr2:149859077-149859157 51 1.32e-04 GTTCTCACCC TCACTCCC CTTGCTTGCC chr22:23045675-23045755 32 1.62e-04 ACCCCTCCTG CCTCTGCC TTTCCTTCCA chr7:112057278-112057358 35 1.62e-04 acttgaaatt acactgca gaactatagt chr13:91410955-91411035 66 1.62e-04 AACCAGATTT CCTCTGCC TGCAATC chr10:85631393-85631473 55 1.62e-04 AAGAAGCTTC ACACTGCA GCTAATGATA chr7:144101420-144101500 2 1.62e-04 a cctctgcc tcccgggttc chr13:92402145-92402225 1 1.62e-04 . cctctgcc tcctgggttc chr22:23456195-23456275 71 1.62e-04 CTGTATGAAA CCTCTGCC TC chr22:23375508-23375588 51 1.76e-04 CTGCCAGTGC TCCCTGCA CCACCCAACT chr22:23405668-23405748 1 2.05e-04 . acactgcc tccttttctc chr22:23440413-23440493 25 2.19e-04 atgatcctga tccctgcc tctcgtaccc chr13:81413389-81413469 59 2.33e-04 atctcttaaa ccactccc cgctaggtac chr13:91006720-91006800 34 2.33e-04 actccgtccc ccactccc caaaaaaaca chr5:38290687-38290767 16 2.62e-04 attactgacc tctctcca aaccatcttg chr22:17038777-17038857 58 2.62e-04 tttgtgtgtg cccctgca tttatcgtac chr22:29600971-29601051 69 2.62e-04 cacacatgca cccctgca caca chr15:22520730-22520810 12 3.05e-04 caaaacccta cccctgcc actaaaccat chr4:184277492-184277572 62 3.05e-04 cctccccctc tctctccc ttctttcctt chr4:190527771-190527851 66 3.05e-04 ccctttctct tctctccc ctttctc chr22:17076162-17076242 5 3.05e-04 AACT TCTCTCCC AGGGTACAAG chr3:25627578-25627658 14 3.35e-04 tcacctcgtg gcactgcc tcgagcctca chr22:23118895-23118975 53 3.35e-04 TAGGcataga gcactgcc cattcattct chr22:23017159-23017239 24 4.07e-04 acacacacac acactcca gtcacagagg chr22:23381709-23381789 59 4.07e-04 tcgtgccacc acactcca gcctggacaa chr22:23423154-23423234 66 4.36e-04 ctcattgtaa tcacagcc tggaata chr13:92370462-92370542 16 6.50e-04 cattctcccg tctcagcc tctggagtag -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YCACTGCM MEME-1 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr13:91831225-91831305 1.5e-05 17_[+1]_55 chr13:90986620-90986700 1.5e-05 1_[+1]_71 chr2:149877635-149877715 1.5e-05 13_[+1]_59 chr7:68489467-68489547 1.5e-05 39_[+1]_33 chr13:91315407-91315487 1.5e-05 18_[+1]_54 chr13:91393563-91393643 1.5e-05 38_[+1]_34 chr22:16984493-16984573 1.5e-05 8_[+1]_64 chr13:90561372-90561452 1.5e-05 41_[+1]_31 chr13:92373444-92373524 1.5e-05 16_[+1]_56 chr22:21911833-21911913 1.5e-05 50_[+1]_22 chr22:23137420-23137500 1.5e-05 38_[+1]_34 chr13:91946610-91946690 1.5e-05 54_[+1]_18 chr13:91843359-91843439 1.5e-05 59_[+1]_13 chr13:92349459-92349539 1.5e-05 9_[+1]_63 chr13:81188979-81189059 1.5e-05 12_[+1]_60 chr13:91345043-91345123 1.5e-05 10_[+1]_62 chr13:91945665-91945745 1.5e-05 20_[+1]_52 chr13:92290626-92290706 1.5e-05 65_[+1]_7 chr6:21326072-21326152 3e-05 70_[+1]_2 chr12:129873946-12987402 3e-05 61_[+1]_11 chr13:91139884-91139964 4.4e-05 52_[+1]_20 chr13:91358209-91358289 4.4e-05 50_[+1]_22 chr22:20946792-20946872 4.4e-05 67_[+1]_5 chr21:11066751-11066831 4.4e-05 26_[+1]_46 chr13:92359776-92359856 4.4e-05 56_[+1]_16 chr13:91743930-91744010 4.4e-05 33_[+1]_39 chr1:19152331-19152411 5.8e-05 6_[+1]_66 chr10:84220969-84221049 5.8e-05 30_[+1]_42 chr10:80664896-80664976 8.9e-05 5_[+1]_67 chr16:5161130-5161210 8.9e-05 69_[+1]_3 chr11:3458817-3458897 8.9e-05 47_[+1]_25 chr13:91914670-91914750 0.00013 64_[+1]_8 chr16:49674216-49674296 0.00013 34_[+1]_38 chr2:149859077-149859157 0.00013 50_[+1]_22 chr22:23045675-23045755 0.00016 31_[+1]_41 chr7:112057278-112057358 0.00016 34_[+1]_38 chr13:91410955-91411035 0.00016 65_[+1]_7 chr10:85631393-85631473 0.00016 54_[+1]_18 chr7:144101420-144101500 0.00016 1_[+1]_71 chr13:92402145-92402225 0.00016 [+1]_72 chr22:23456195-23456275 0.00016 70_[+1]_2 chr22:23375508-23375588 0.00018 50_[+1]_22 chr22:23405668-23405748 0.0002 [+1]_72 chr22:23440413-23440493 0.00022 24_[+1]_48 chr13:81413389-81413469 0.00023 58_[+1]_14 chr13:91006720-91006800 0.00023 33_[+1]_39 chr5:38290687-38290767 0.00026 15_[+1]_57 chr22:17038777-17038857 0.00026 57_[+1]_15 chr22:29600971-29601051 0.00026 68_[+1]_4 chr15:22520730-22520810 0.00031 11_[+1]_61 chr4:184277492-184277572 0.00031 61_[+1]_11 chr4:190527771-190527851 0.00031 65_[+1]_7 chr22:17076162-17076242 0.00031 4_[+1]_68 chr3:25627578-25627658 0.00033 13_[+1]_59 chr22:23118895-23118975 0.00033 52_[+1]_20 chr22:23017159-23017239 0.00041 23_[+1]_49 chr22:23381709-23381789 0.00041 58_[+1]_14 chr22:23423154-23423234 0.00044 65_[+1]_7 chr13:92370462-92370542 0.00065 15_[+1]_57 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YCACTGCM MEME-1 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF YCACTGCM width=8 seqs=59 chr13:91831225-91831305 ( 18) TCACTGCA 1 chr13:90986620-90986700 ( 2) TCACTGCA 1 chr2:149877635-149877715 ( 14) TCACTGCA 1 chr7:68489467-68489547 ( 40) TCACTGCA 1 chr13:91315407-91315487 ( 19) TCACTGCA 1 chr13:91393563-91393643 ( 39) TCACTGCA 1 chr22:16984493-16984573 ( 9) TCACTGCA 1 chr13:90561372-90561452 ( 42) TCACTGCA 1 chr13:92373444-92373524 ( 17) TCACTGCA 1 chr22:21911833-21911913 ( 51) TCACTGCA 1 chr22:23137420-23137500 ( 39) TCACTGCA 1 chr13:91946610-91946690 ( 55) TCACTGCA 1 chr13:91843359-91843439 ( 60) TCACTGCA 1 chr13:92349459-92349539 ( 10) TCACTGCA 1 chr13:81188979-81189059 ( 13) TCACTGCA 1 chr13:91345043-91345123 ( 11) TCACTGCA 1 chr13:91945665-91945745 ( 21) TCACTGCA 1 chr13:92290626-92290706 ( 66) TCACTGCA 1 chr6:21326072-21326152 ( 71) TCACTGCC 1 chr12:129873946-12987402 ( 62) TCACTGCC 1 chr13:91139884-91139964 ( 53) CCACTGCA 1 chr13:91358209-91358289 ( 51) CCACTGCA 1 chr22:20946792-20946872 ( 68) CCACTGCA 1 chr21:11066751-11066831 ( 27) CCACTGCA 1 chr13:92359776-92359856 ( 57) CCACTGCA 1 chr13:91743930-91744010 ( 34) CCACTGCA 1 chr1:19152331-19152411 ( 7) CCACTGCC 1 chr10:84220969-84221049 ( 31) CCACTGCC 1 chr10:80664896-80664976 ( 6) TCTCTGCC 1 chr16:5161130-5161210 ( 70) TCTCTGCC 1 chr11:3458817-3458897 ( 48) TCTCTGCC 1 chr13:91914670-91914750 ( 65) TCACTCCC 1 chr16:49674216-49674296 ( 35) TCACTCCC 1 chr2:149859077-149859157 ( 51) TCACTCCC 1 chr22:23045675-23045755 ( 32) CCTCTGCC 1 chr7:112057278-112057358 ( 35) ACACTGCA 1 chr13:91410955-91411035 ( 66) CCTCTGCC 1 chr10:85631393-85631473 ( 55) ACACTGCA 1 chr7:144101420-144101500 ( 2) CCTCTGCC 1 chr13:92402145-92402225 ( 1) CCTCTGCC 1 chr22:23456195-23456275 ( 71) CCTCTGCC 1 chr22:23375508-23375588 ( 51) TCCCTGCA 1 chr22:23405668-23405748 ( 1) ACACTGCC 1 chr22:23440413-23440493 ( 25) TCCCTGCC 1 chr13:81413389-81413469 ( 59) CCACTCCC 1 chr13:91006720-91006800 ( 34) CCACTCCC 1 chr5:38290687-38290767 ( 16) TCTCTCCA 1 chr22:17038777-17038857 ( 58) CCCCTGCA 1 chr22:29600971-29601051 ( 69) CCCCTGCA 1 chr15:22520730-22520810 ( 12) CCCCTGCC 1 chr4:184277492-184277572 ( 62) TCTCTCCC 1 chr4:190527771-190527851 ( 66) TCTCTCCC 1 chr22:17076162-17076242 ( 5) TCTCTCCC 1 chr3:25627578-25627658 ( 14) GCACTGCC 1 chr22:23118895-23118975 ( 53) GCACTGCC 1 chr22:23017159-23017239 ( 24) ACACTCCA 1 chr22:23381709-23381789 ( 59) ACACTCCA 1 chr22:23423154-23423234 ( 66) TCACAGCC 1 chr13:92370462-92370542 ( 16) TCTCAGCC 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YCACTGCM MEME-1 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 8.92768 E= 8.2e-019 -156 31 -287 117 -1253 203 -1253 -1253 147 -153 -1253 -21 -1253 203 -1253 -1253 -288 -1253 -1253 192 -1253 -40 171 -1253 -1253 203 -1253 -1253 112 90 -1253 -1253 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YCACTGCM MEME-1 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 59 E= 8.2e-019 0.084746 0.305085 0.033898 0.576271 0.000000 1.000000 0.000000 0.000000 0.694915 0.084746 0.000000 0.220339 0.000000 1.000000 0.000000 0.000000 0.033898 0.000000 0.000000 0.966102 0.000000 0.186441 0.813559 0.000000 0.000000 1.000000 0.000000 0.000000 0.542373 0.457627 0.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YCACTGCM MEME-1 regular expression -------------------------------------------------------------------------------- [TC]C[AT]CTGC[AC] -------------------------------------------------------------------------------- Time 5.16 secs. ******************************************************************************** ******************************************************************************** MOTIF CCWGCCTS MEME-2 width = 8 sites = 59 llr = 460 E-value = 4.8e-013 ******************************************************************************** -------------------------------------------------------------------------------- Motif CCWGCCTS MEME-2 Description -------------------------------------------------------------------------------- Simplified A ::5::::: pos.-specific C 8a:28a:5 probability G :::82::5 matrix T 2:511:a: bits 2.0 * 1.8 * ** 1.6 * ** 1.4 ** ** Relative 1.2 ** *** Entropy 1.0 ******** (11.3 bits) 0.8 ******** 0.6 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel CCAGCCTC consensus T G sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCWGCCTS MEME-2 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr13:90946140-90946220 46 2.84e-05 gtactggcag ccagcctg caaatgtaac chr13:91139884-91139964 63 2.84e-05 ccactgcact ccagcctg gcgacagagc chr13:91358209-91358289 61 2.84e-05 ccactgcact ccagcctg gacaacagag chr22:22795723-22795803 17 2.84e-05 gagtgatccg ccagcctc ggcctcccga chr13:81369545-81369625 33 2.84e-05 gagttcaaga ccagcctg gccaacatgg chr13:91897778-91897858 7 2.84e-05 tgcact ccagcctc acgcctgttc chr13:91202375-91202455 73 2.84e-05 ccactgaact ccagcctg chr21:11066751-11066831 37 2.84e-05 ccactgcact ccagcctg ggtgacagag chr13:91006720-91006800 2 2.84e-05 t ccagcctg ggggacagag chr13:90870841-90870921 20 2.84e-05 gatttcaaga ccagcctg gccaacatgg chr13:91743930-91744010 44 2.84e-05 ccactgcact ccagcctg ggcgacagag chr18:6042341-6042421 67 5.74e-05 TAAATCCACA CCTGCCTC CAGTCC chr1:17248230-17248310 66 5.74e-05 cctttggctc cctgcctc tgcttcc chr13:90986620-90986700 39 5.74e-05 aagctattcc cctgcctc agacagactc chr7:134415857-134415937 14 5.74e-05 AAcatctcct cctgcctg ccttgaagct chr5:17146725-17146805 46 5.74e-05 tttcttcctt cctgcctg cctttccttt chr13:91315407-91315487 56 5.74e-05 aagttattct cctgcctc agcctcctga chr22:16984493-16984573 46 5.74e-05 aagtgattct cctgcctc agcctcccaa chr13:92317854-92317934 12 5.74e-05 atgccattct cctgcctc agcctcccaa chr7:144101420-144101500 30 5.74e-05 aagcgattct cctgcctc agcctcgcga chr11:66316453-66316533 16 5.74e-05 ccacctccct cctgcctg aggcttccct chr13:92349459-92349539 47 5.74e-05 aaacgattct cctgcctc agcctcccaa chr13:81188979-81189059 50 5.74e-05 aagtgattct cctgcctc agcctcctga chr21:11138816-11138896 15 5.74e-05 aagcaattct cctgcctc agcctcccag chr13:91345043-91345123 47 5.74e-05 cagccattct cctgcctc agccacccga chr15:26003844-26003924 24 8.53e-05 atcacctgct ccaccctc attccgacca chr2:149877635-149877715 57 1.15e-04 ttctcctgtt tcagcctc ccaagtagct chr13:92435779-92435859 24 1.15e-04 ttcttatgcc tcagcctc ctgagtaact chr13:92402145-92402225 34 1.15e-04 attctcctcc tcagcctc ccaagtagct chr22:17003686-17003766 68 1.72e-04 cctatgttgg ccaggctg ctctg chr6:21326072-21326152 40 1.72e-04 gctctgtcac ccaggctg gagtgcaatg chr4:184277492-184277572 36 1.72e-04 ctcctttctg cctccctc ccttctttcc chr13:90561372-90561452 11 1.72e-04 cactctgtca ccaggctg gaatgcagtg chr22:23101566-23101646 55 1.72e-04 GGCAACACGG CCTCCCTG ACCATCTCTG chr22:23405668-23405748 39 1.72e-04 gcagacatca cctccctg gagggtcgcc chr22:21911833-21911913 20 1.72e-04 gctctgtcac ccaggctg gagtgcagtg chr22:16918392-16918472 50 1.72e-04 cacttgttgc ccaggctg gagtgcaatg chr13:91843359-91843439 29 1.72e-04 gtcctgtcac ccaggctg gagtgcagtg chr22:23287539-23287619 46 1.72e-04 gctctgtcac ccaggctg gagtgcagcg chr13:92359776-92359856 31 1.72e-04 cctgggacat ccaggctg cagtgagcca chr13:91945665-91945745 58 1.72e-04 aagcaattct cctccctc aacctcctga chr13:92290626-92290706 35 1.72e-04 accatgatgc ccaggctg gagtgcaacg chr22:22479813-22479893 34 1.72e-04 ACAGTCCTTC CCTCCCTG GACTCCAGGC chr13:91825681-91825761 59 2.03e-04 CTTCGGATCA TCTGCCTG CAAGACAGAC chr7:68489467-68489547 51 2.03e-04 cactgcaaca tctgcctc ctgggttcaa chr22:23137420-23137500 50 2.03e-04 cactgcaacc tctgcctc ctggattcaa chr22:23364716-23364796 40 2.61e-04 gagatcaaga ccatcctg gctaacacgg chr7:112337772-112337852 7 2.61e-04 tgcact ccatcctg ggcaacattg chr13:90914394-90914474 55 2.91e-04 aaccagttag ccagtctc caggaagttc chr4:178171342-178171422 44 3.21e-04 TGGTGCCTCG CCTTCCTC CCGCCGCCTA chr13:92373444-92373524 54 3.51e-04 aagcaattct cctgtctc agccccttga chr3:39237615-39237695 27 3.51e-04 aaagtgagat cctgtctc aaaaaaaaga chr20:43941974-43942054 19 3.80e-04 atcctaaccc tcaccctc accctaaccc chr11:65669778-65669858 5 3.80e-04 CTTG TCACCCTC TTGTCATCAT chr13:114489366-11448944 27 3.80e-04 atcactgtca tcaccctc gtcaccatca chr13:91489983-91490063 18 4.96e-04 ctagtatgtt ccagccac agatgccttc chr13:91863940-91864020 55 4.96e-04 tccctcaggg tctccctg tcctagtgaa chr22:23375508-23375588 40 5.85e-04 TCTAAACCAA CCTGCCAG TGCTCCCTGC chr13:81233439-81233519 26 6.14e-04 cagctttttc ccaGCATC AAacccaata -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCWGCCTS MEME-2 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr13:90946140-90946220 2.8e-05 45_[+2]_27 chr13:91139884-91139964 2.8e-05 62_[+2]_10 chr13:91358209-91358289 2.8e-05 60_[+2]_12 chr22:22795723-22795803 2.8e-05 16_[+2]_56 chr13:81369545-81369625 2.8e-05 32_[+2]_40 chr13:91897778-91897858 2.8e-05 6_[+2]_66 chr13:91202375-91202455 2.8e-05 72_[+2] chr21:11066751-11066831 2.8e-05 36_[+2]_36 chr13:91006720-91006800 2.8e-05 1_[+2]_71 chr13:90870841-90870921 2.8e-05 19_[+2]_53 chr13:91743930-91744010 2.8e-05 43_[+2]_29 chr18:6042341-6042421 5.7e-05 66_[+2]_6 chr1:17248230-17248310 5.7e-05 65_[+2]_7 chr13:90986620-90986700 5.7e-05 38_[+2]_34 chr7:134415857-134415937 5.7e-05 13_[+2]_59 chr5:17146725-17146805 5.7e-05 45_[+2]_27 chr13:91315407-91315487 5.7e-05 55_[+2]_17 chr22:16984493-16984573 5.7e-05 45_[+2]_27 chr13:92317854-92317934 5.7e-05 11_[+2]_61 chr7:144101420-144101500 5.7e-05 29_[+2]_43 chr11:66316453-66316533 5.7e-05 15_[+2]_57 chr13:92349459-92349539 5.7e-05 46_[+2]_26 chr13:81188979-81189059 5.7e-05 49_[+2]_23 chr21:11138816-11138896 5.7e-05 14_[+2]_58 chr13:91345043-91345123 5.7e-05 46_[+2]_26 chr15:26003844-26003924 8.5e-05 23_[+2]_49 chr2:149877635-149877715 0.00011 56_[+2]_16 chr13:92435779-92435859 0.00011 23_[+2]_49 chr13:92402145-92402225 0.00011 33_[+2]_39 chr22:17003686-17003766 0.00017 67_[+2]_5 chr6:21326072-21326152 0.00017 39_[+2]_33 chr4:184277492-184277572 0.00017 35_[+2]_37 chr13:90561372-90561452 0.00017 10_[+2]_62 chr22:23101566-23101646 0.00017 54_[+2]_18 chr22:23405668-23405748 0.00017 38_[+2]_34 chr22:21911833-21911913 0.00017 19_[+2]_53 chr22:16918392-16918472 0.00017 49_[+2]_23 chr13:91843359-91843439 0.00017 28_[+2]_44 chr22:23287539-23287619 0.00017 45_[+2]_27 chr13:92359776-92359856 0.00017 30_[+2]_42 chr13:91945665-91945745 0.00017 57_[+2]_15 chr13:92290626-92290706 0.00017 34_[+2]_38 chr22:22479813-22479893 0.00017 33_[+2]_39 chr13:91825681-91825761 0.0002 58_[+2]_14 chr7:68489467-68489547 0.0002 50_[+2]_22 chr22:23137420-23137500 0.0002 49_[+2]_23 chr22:23364716-23364796 0.00026 39_[+2]_33 chr7:112337772-112337852 0.00026 6_[+2]_66 chr13:90914394-90914474 0.00029 54_[+2]_18 chr4:178171342-178171422 0.00032 43_[+2]_29 chr13:92373444-92373524 0.00035 53_[+2]_19 chr3:39237615-39237695 0.00035 26_[+2]_46 chr20:43941974-43942054 0.00038 18_[+2]_54 chr11:65669778-65669858 0.00038 4_[+2]_68 chr13:114489366-11448944 0.00038 26_[+2]_46 chr13:91489983-91490063 0.0005 17_[+2]_55 chr13:91863940-91864020 0.0005 54_[+2]_18 chr22:23375508-23375588 0.00058 39_[+2]_33 chr13:81233439-81233519 0.00061 25_[+2]_47 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCWGCCTS MEME-2 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF CCWGCCTS width=8 seqs=59 chr13:90946140-90946220 ( 46) CCAGCCTG 1 chr13:91139884-91139964 ( 63) CCAGCCTG 1 chr13:91358209-91358289 ( 61) CCAGCCTG 1 chr22:22795723-22795803 ( 17) CCAGCCTC 1 chr13:81369545-81369625 ( 33) CCAGCCTG 1 chr13:91897778-91897858 ( 7) CCAGCCTC 1 chr13:91202375-91202455 ( 73) CCAGCCTG 1 chr21:11066751-11066831 ( 37) CCAGCCTG 1 chr13:91006720-91006800 ( 2) CCAGCCTG 1 chr13:90870841-90870921 ( 20) CCAGCCTG 1 chr13:91743930-91744010 ( 44) CCAGCCTG 1 chr18:6042341-6042421 ( 67) CCTGCCTC 1 chr1:17248230-17248310 ( 66) CCTGCCTC 1 chr13:90986620-90986700 ( 39) CCTGCCTC 1 chr7:134415857-134415937 ( 14) CCTGCCTG 1 chr5:17146725-17146805 ( 46) CCTGCCTG 1 chr13:91315407-91315487 ( 56) CCTGCCTC 1 chr22:16984493-16984573 ( 46) CCTGCCTC 1 chr13:92317854-92317934 ( 12) CCTGCCTC 1 chr7:144101420-144101500 ( 30) CCTGCCTC 1 chr11:66316453-66316533 ( 16) CCTGCCTG 1 chr13:92349459-92349539 ( 47) CCTGCCTC 1 chr13:81188979-81189059 ( 50) CCTGCCTC 1 chr21:11138816-11138896 ( 15) CCTGCCTC 1 chr13:91345043-91345123 ( 47) CCTGCCTC 1 chr15:26003844-26003924 ( 24) CCACCCTC 1 chr2:149877635-149877715 ( 57) TCAGCCTC 1 chr13:92435779-92435859 ( 24) TCAGCCTC 1 chr13:92402145-92402225 ( 34) TCAGCCTC 1 chr22:17003686-17003766 ( 68) CCAGGCTG 1 chr6:21326072-21326152 ( 40) CCAGGCTG 1 chr4:184277492-184277572 ( 36) CCTCCCTC 1 chr13:90561372-90561452 ( 11) CCAGGCTG 1 chr22:23101566-23101646 ( 55) CCTCCCTG 1 chr22:23405668-23405748 ( 39) CCTCCCTG 1 chr22:21911833-21911913 ( 20) CCAGGCTG 1 chr22:16918392-16918472 ( 50) CCAGGCTG 1 chr13:91843359-91843439 ( 29) CCAGGCTG 1 chr22:23287539-23287619 ( 46) CCAGGCTG 1 chr13:92359776-92359856 ( 31) CCAGGCTG 1 chr13:91945665-91945745 ( 58) CCTCCCTC 1 chr13:92290626-92290706 ( 35) CCAGGCTG 1 chr22:22479813-22479893 ( 34) CCTCCCTG 1 chr13:91825681-91825761 ( 59) TCTGCCTG 1 chr7:68489467-68489547 ( 51) TCTGCCTC 1 chr22:23137420-23137500 ( 50) TCTGCCTC 1 chr22:23364716-23364796 ( 40) CCATCCTG 1 chr7:112337772-112337852 ( 7) CCATCCTG 1 chr13:90914394-90914474 ( 55) CCAGTCTC 1 chr4:178171342-178171422 ( 44) CCTTCCTC 1 chr13:92373444-92373524 ( 54) CCTGTCTC 1 chr3:39237615-39237695 ( 27) CCTGTCTC 1 chr20:43941974-43942054 ( 19) TCACCCTC 1 chr11:65669778-65669858 ( 5) TCACCCTC 1 chr13:114489366-11448944 ( 27) TCACCCTC 1 chr13:91489983-91490063 ( 18) CCAGCCAC 1 chr13:91863940-91864020 ( 55) TCTCCCTG 1 chr22:23375508-23375588 ( 40) CCTGCCAG 1 chr13:81233439-81233519 ( 26) CCAGCATC 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCWGCCTS MEME-2 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 8.92768 E= 4.8e-013 -1253 176 -1253 -59 -1253 203 -1253 -1253 112 -1253 -1253 84 -1253 -53 165 -233 -1253 170 -71 -233 -388 200 -1253 -1253 -288 -1253 -1253 192 -1253 105 98 -1253 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCWGCCTS MEME-2 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 59 E= 4.8e-013 0.000000 0.830508 0.000000 0.169492 0.000000 1.000000 0.000000 0.000000 0.542373 0.000000 0.000000 0.457627 0.000000 0.169492 0.779661 0.050847 0.000000 0.796610 0.152542 0.050847 0.016949 0.983051 0.000000 0.000000 0.033898 0.000000 0.000000 0.966102 0.000000 0.508475 0.491525 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCWGCCTS MEME-2 regular expression -------------------------------------------------------------------------------- CC[AT]GCCT[CG] -------------------------------------------------------------------------------- Time 8.93 secs. ******************************************************************************** ******************************************************************************** MOTIF CACACACA MEME-3 width = 8 sites = 33 llr = 300 E-value = 1.3e-011 ******************************************************************************** -------------------------------------------------------------------------------- Motif CACACACA MEME-3 Description -------------------------------------------------------------------------------- Simplified A :a:8:a:a pos.-specific C 9:819:9: probability G 1:2:::1: matrix T :::11::: bits 2.0 * * 1.8 * * * 1.6 * **** 1.4 ** **** Relative 1.2 ******** Entropy 1.0 ******** (13.1 bits) 0.8 ******** 0.6 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel CACACACA consensus G sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CACACACA MEME-3 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr18:6042341-6042421 40 1.41e-05 cagacacata cacacaca cCAAGCACGT chr21:40497777-40497857 6 1.41e-05 gtact cacacaca tgcatgccac chr22:23017159-23017239 9 1.41e-05 cgcacaca cacacaca cacacacaca chr16:49674216-49674296 14 1.41e-05 cacccaccat cacacaca ttcattcaca chr22:22610615-22610695 57 1.41e-05 AACAGGcaca cacacaca gccacacaag chr21:44919729-44919809 39 1.41e-05 gcacacatat cacacaca gcacacaTGT chr3:13789228-13789308 66 1.41e-05 cacatgcaca cacacaca cacacag chr5:33672175-33672255 70 1.41e-05 cacatacata cacacaca cat chr6:11427602-11427682 46 1.41e-05 acaccacata cacacaca cccctcacac chr5:142716-142796 22 1.41e-05 ccacatacca cacacaca atcacacaaa chr5:6797628-6797708 49 1.41e-05 Ccacacaata cacacaca ccacacatac chr8:48116032-48116112 27 1.41e-05 caggcacgta cacacaca tatagacaga chr2:105495453-105495533 29 1.41e-05 acatatacag cacacaca acatatacat chr6:6522486-6522566 55 1.41e-05 catgctctct cacacaca ctcaaacatg chr22:29600971-29601051 29 1.41e-05 atcaagcatg cacacaca tccatcatac chr13:91006720-91006800 65 1.41e-05 aacaaaataa cacacaca caaaaaaa chr7:155585830-155585910 42 1.41e-05 aaagcacatc cacacaca catgcacatc chr14:19613018-19613098 10 2.84e-05 ACAGGGACA CAGACACA CGGAGACATC chr10:35992934-35993014 3 2.84e-05 AA CAGacaca ccaacacacc chr1:228107442-228107522 55 4.28e-05 gcactcacaa cactcaca acatacgcac chr2:149859077-149859157 71 4.28e-05 TGCTTGCCTT CACTCACA CC chr13:91594632-91594712 8 5.75e-05 CTTTGTA CACATACA TAGCTTCAGT chr7:87860120-87860200 7 7.13e-05 GGTATC CACCCACA TTCACGTGTA chr12:129873946-12987402 1 7.13e-05 . CACCCACA TCAATACTAA chr13:91635305-91635385 1 8.56e-05 . gacacaca gtgggtaaca chr13:90655953-90656033 71 8.56e-05 AGAAGctaag gacacaca gc chr22:23000045-23000125 5 9.99e-05 caac cacacaga ggagggcaaa chr22:23379752-23379832 3 1.43e-04 gt cacacacc acagggtgcc chr10:47092840-47092920 5 1.43e-04 gatc cagtcaca gtcggcctgc chr22:23045675-23045755 10 1.58e-04 GGGCACTTC CAGATACA CCCGACCCCT chr11:3458817-3458897 1 1.58e-04 . CAGATACA CGATGGTCCT chr21:46313799-46313879 17 2.01e-04 gaggcagaga cagacaga gatgggcaga chr1:209568841-209568921 60 2.30e-04 gagtgaggaa aagacaca ggaaaatata -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CACACACA MEME-3 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr18:6042341-6042421 1.4e-05 39_[+3]_33 chr21:40497777-40497857 1.4e-05 5_[+3]_67 chr22:23017159-23017239 1.4e-05 8_[+3]_64 chr16:49674216-49674296 1.4e-05 13_[+3]_59 chr22:22610615-22610695 1.4e-05 56_[+3]_16 chr21:44919729-44919809 1.4e-05 38_[+3]_34 chr3:13789228-13789308 1.4e-05 65_[+3]_7 chr5:33672175-33672255 1.4e-05 69_[+3]_3 chr6:11427602-11427682 1.4e-05 45_[+3]_27 chr5:142716-142796 1.4e-05 21_[+3]_51 chr5:6797628-6797708 1.4e-05 48_[+3]_24 chr8:48116032-48116112 1.4e-05 26_[+3]_46 chr2:105495453-105495533 1.4e-05 28_[+3]_44 chr6:6522486-6522566 1.4e-05 54_[+3]_18 chr22:29600971-29601051 1.4e-05 28_[+3]_44 chr13:91006720-91006800 1.4e-05 64_[+3]_8 chr7:155585830-155585910 1.4e-05 41_[+3]_31 chr14:19613018-19613098 2.8e-05 9_[+3]_63 chr10:35992934-35993014 2.8e-05 2_[+3]_70 chr1:228107442-228107522 4.3e-05 54_[+3]_18 chr2:149859077-149859157 4.3e-05 70_[+3]_2 chr13:91594632-91594712 5.7e-05 7_[+3]_65 chr7:87860120-87860200 7.1e-05 6_[+3]_66 chr12:129873946-12987402 7.1e-05 [+3]_72 chr13:91635305-91635385 8.6e-05 [+3]_72 chr13:90655953-90656033 8.6e-05 70_[+3]_2 chr22:23000045-23000125 0.0001 4_[+3]_68 chr22:23379752-23379832 0.00014 2_[+3]_70 chr10:47092840-47092920 0.00014 4_[+3]_68 chr22:23045675-23045755 0.00016 9_[+3]_63 chr11:3458817-3458897 0.00016 [+3]_72 chr21:46313799-46313879 0.0002 16_[+3]_56 chr1:209568841-209568921 0.00023 59_[+3]_13 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CACACACA MEME-3 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF CACACACA width=8 seqs=33 chr18:6042341-6042421 ( 40) CACACACA 1 chr21:40497777-40497857 ( 6) CACACACA 1 chr22:23017159-23017239 ( 9) CACACACA 1 chr16:49674216-49674296 ( 14) CACACACA 1 chr22:22610615-22610695 ( 57) CACACACA 1 chr21:44919729-44919809 ( 39) CACACACA 1 chr3:13789228-13789308 ( 66) CACACACA 1 chr5:33672175-33672255 ( 70) CACACACA 1 chr6:11427602-11427682 ( 46) CACACACA 1 chr5:142716-142796 ( 22) CACACACA 1 chr5:6797628-6797708 ( 49) CACACACA 1 chr8:48116032-48116112 ( 27) CACACACA 1 chr2:105495453-105495533 ( 29) CACACACA 1 chr6:6522486-6522566 ( 55) CACACACA 1 chr22:29600971-29601051 ( 29) CACACACA 1 chr13:91006720-91006800 ( 65) CACACACA 1 chr7:155585830-155585910 ( 42) CACACACA 1 chr14:19613018-19613098 ( 10) CAGACACA 1 chr10:35992934-35993014 ( 3) CAGACACA 1 chr1:228107442-228107522 ( 55) CACTCACA 1 chr2:149859077-149859157 ( 71) CACTCACA 1 chr13:91594632-91594712 ( 8) CACATACA 1 chr7:87860120-87860200 ( 7) CACCCACA 1 chr12:129873946-12987402 ( 1) CACCCACA 1 chr13:91635305-91635385 ( 1) GACACACA 1 chr13:90655953-90656033 ( 71) GACACACA 1 chr22:23000045-23000125 ( 5) CACACAGA 1 chr22:23379752-23379832 ( 3) CACACACC 1 chr10:47092840-47092920 ( 5) CAGTCACA 1 chr22:23045675-23045755 ( 10) CAGATACA 1 chr11:3458817-3458897 ( 1) CAGATACA 1 chr21:46313799-46313879 ( 17) CAGACAGA 1 chr1:209568841-209568921 ( 60) AAGACACA 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CACACACA MEME-3 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 9.87609 E= 1.3e-011 -304 189 -204 -1169 200 -1169 -1169 -1169 -1169 168 -23 -1169 176 -202 -1169 -149 -1169 189 -1169 -149 200 -1169 -1169 -1169 -1169 194 -204 -1169 195 -301 -1169 -1169 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CACACACA MEME-3 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 33 E= 1.3e-011 0.030303 0.909091 0.060606 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.787879 0.212121 0.000000 0.848485 0.060606 0.000000 0.090909 0.000000 0.909091 0.000000 0.090909 1.000000 0.000000 0.000000 0.000000 0.000000 0.939394 0.060606 0.000000 0.969697 0.030303 0.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CACACACA MEME-3 regular expression -------------------------------------------------------------------------------- CA[CG]ACACA -------------------------------------------------------------------------------- Time 12.56 secs. ******************************************************************************** ******************************************************************************** MOTIF CACMMHCA MEME-4 width = 8 sites = 31 llr = 260 E-value = 1.1e+001 ******************************************************************************** -------------------------------------------------------------------------------- Motif CACMMHCA MEME-4 Description -------------------------------------------------------------------------------- Simplified A :a:465:a pos.-specific C a:9643a: probability G :::::::: matrix T ::1::2:: bits 2.0 ** ** 1.8 ** ** 1.6 ** ** 1.4 *** ** Relative 1.2 *** ** Entropy 1.0 ***** ** (12.1 bits) 0.8 ***** ** 0.6 ***** ** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel CACCAACA consensus ACC sequence T -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CACMMHCA MEME-4 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr13:91594632-91594712 58 1.41e-05 GACAAAACTA CACCAACA TTCCCAAGTG chr12:129873946-12987402 72 1.41e-05 tcactgccaa caccaaca c chr10:35992934-35993014 66 1.41e-05 cacacatact caccaaca tacacgt chr6:50654306-50654386 64 1.41e-05 ttcatcagca caccaaca ccatcacca chr1:19152331-19152411 41 2.79e-05 tcattatcac caccacca tcaccatctc chr10:84220969-84221049 23 2.79e-05 acaccaccac caccacca ccactgccac chr7:126899568-126899648 47 2.79e-05 tcaccatcac caccacca ccaccttcac chr16:26553640-26553720 34 2.79e-05 ctacaaccac caccacca tcaatatcac chr13:92317854-92317934 51 2.79e-05 tgcaggcgcc caccacca caccccgcta chr13:92402145-92402225 67 2.79e-05 cacaggcatg caccacca agcccg chr7:154570414-154570494 64 2.79e-05 ccaccagctc caccacca tcaccacca chr21:40497777-40497857 25 5.60e-05 gcatgccaca cacccaca cagcacaaat chr5:33672175-33672255 56 5.60e-05 catccacaca cacccaca tacatacaca chr6:11427602-11427682 31 5.60e-05 actccctcga cacaaaca ccacatacac chr5:142716-142796 34 5.60e-05 cacacaatca cacaaaca cagtaacaca chr8:48116032-48116112 49 7.04e-05 gacagatatg caccatca cacatacaca chr13:114489366-11448944 64 7.04e-05 tcatcaccat caccatca tcaGTGtca chr13:90914394-90914474 42 9.80e-05 acattttgtt cacaacca gttagccagt chr18:6042341-6042421 24 1.12e-04 catacgtgca cacacaca gacacataca chr3:13789228-13789308 52 1.12e-04 cacacagatg cacacaca tgcacacaca chr22:29600971-29601051 57 1.12e-04 acacatacga cacacaca tgcacccctg chr7:155585830-155585910 60 1.12e-04 catgcacatc cacacaca tctagacaca chr2:149859077-149859157 23 1.41e-04 CGCACATTCA CACAATCA CTCTCGTGCA chr22:23000045-23000125 68 1.41e-04 catctggaaa caccctca tagac chr2:105495453-105495533 69 1.55e-04 caacacacag cacaccca gcac chr16:49674216-49674296 44 1.69e-04 atcactccca cacactca cactatcact chr22:22610615-22610695 29 1.69e-04 gattcacaga cacactca TCATCACATA chr14:19613018-19613098 69 1.98e-04 GGACACGAGA CATCACCA CACT chr22:23379752-23379832 63 2.28e-04 taCACTTTCC CATCCACA TTCCATCTTG chr11:65669778-65669858 17 2.43e-04 ACCCTCTTGT CATCATCA TCTCtgtgtg chr5:6797628-6797708 66 2.86e-04 accacacata catacaca acacaca -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CACMMHCA MEME-4 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr13:91594632-91594712 1.4e-05 57_[+4]_15 chr12:129873946-12987402 1.4e-05 71_[+4]_1 chr10:35992934-35993014 1.4e-05 65_[+4]_7 chr6:50654306-50654386 1.4e-05 63_[+4]_9 chr1:19152331-19152411 2.8e-05 40_[+4]_32 chr10:84220969-84221049 2.8e-05 22_[+4]_50 chr7:126899568-126899648 2.8e-05 46_[+4]_26 chr16:26553640-26553720 2.8e-05 33_[+4]_39 chr13:92317854-92317934 2.8e-05 50_[+4]_22 chr13:92402145-92402225 2.8e-05 66_[+4]_6 chr7:154570414-154570494 2.8e-05 63_[+4]_9 chr21:40497777-40497857 5.6e-05 24_[+4]_48 chr5:33672175-33672255 5.6e-05 55_[+4]_17 chr6:11427602-11427682 5.6e-05 30_[+4]_42 chr5:142716-142796 5.6e-05 33_[+4]_39 chr8:48116032-48116112 7e-05 48_[+4]_24 chr13:114489366-11448944 7e-05 63_[+4]_9 chr13:90914394-90914474 9.8e-05 41_[+4]_31 chr18:6042341-6042421 0.00011 23_[+4]_49 chr3:13789228-13789308 0.00011 51_[+4]_21 chr22:29600971-29601051 0.00011 56_[+4]_16 chr7:155585830-155585910 0.00011 59_[+4]_13 chr2:149859077-149859157 0.00014 22_[+4]_50 chr22:23000045-23000125 0.00014 67_[+4]_5 chr2:105495453-105495533 0.00015 68_[+4]_4 chr16:49674216-49674296 0.00017 43_[+4]_29 chr22:22610615-22610695 0.00017 28_[+4]_44 chr14:19613018-19613098 0.0002 68_[+4]_4 chr22:23379752-23379832 0.00023 62_[+4]_10 chr11:65669778-65669858 0.00024 16_[+4]_56 chr5:6797628-6797708 0.00029 65_[+4]_7 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CACMMHCA MEME-4 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF CACMMHCA width=8 seqs=31 chr13:91594632-91594712 ( 58) CACCAACA 1 chr12:129873946-12987402 ( 72) CACCAACA 1 chr10:35992934-35993014 ( 66) CACCAACA 1 chr6:50654306-50654386 ( 64) CACCAACA 1 chr1:19152331-19152411 ( 41) CACCACCA 1 chr10:84220969-84221049 ( 23) CACCACCA 1 chr7:126899568-126899648 ( 47) CACCACCA 1 chr16:26553640-26553720 ( 34) CACCACCA 1 chr13:92317854-92317934 ( 51) CACCACCA 1 chr13:92402145-92402225 ( 67) CACCACCA 1 chr7:154570414-154570494 ( 64) CACCACCA 1 chr21:40497777-40497857 ( 25) CACCCACA 1 chr5:33672175-33672255 ( 56) CACCCACA 1 chr6:11427602-11427682 ( 31) CACAAACA 1 chr5:142716-142796 ( 34) CACAAACA 1 chr8:48116032-48116112 ( 49) CACCATCA 1 chr13:114489366-11448944 ( 64) CACCATCA 1 chr13:90914394-90914474 ( 42) CACAACCA 1 chr18:6042341-6042421 ( 24) CACACACA 1 chr3:13789228-13789308 ( 52) CACACACA 1 chr22:29600971-29601051 ( 57) CACACACA 1 chr7:155585830-155585910 ( 60) CACACACA 1 chr2:149859077-149859157 ( 23) CACAATCA 1 chr22:23000045-23000125 ( 68) CACCCTCA 1 chr2:105495453-105495533 ( 69) CACACCCA 1 chr16:49674216-49674296 ( 44) CACACTCA 1 chr22:22610615-22610695 ( 29) CACACTCA 1 chr14:19613018-19613098 ( 69) CATCACCA 1 chr22:23379752-23379832 ( 63) CATCCACA 1 chr11:65669778-65669858 ( 17) CATCATCA 1 chr5:6797628-6797708 ( 66) CATACACA 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CACMMHCA MEME-4 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 10.4993 E= 1.1e+001 -1160 203 -1160 -1160 200 -1160 -1160 -1160 -1160 183 -1160 -99 63 132 -1160 -1160 129 66 -1160 -1160 85 39 -1160 -18 -1160 203 -1160 -1160 200 -1160 -1160 -1160 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CACMMHCA MEME-4 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 31 E= 1.1e+001 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.870968 0.000000 0.129032 0.387097 0.612903 0.000000 0.000000 0.612903 0.387097 0.000000 0.000000 0.451613 0.322581 0.000000 0.225806 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CACMMHCA MEME-4 regular expression -------------------------------------------------------------------------------- CAC[CA][AC][ACT]CA -------------------------------------------------------------------------------- Time 16.15 secs. ******************************************************************************** ******************************************************************************** MOTIF CCAGCTAC MEME-5 width = 8 sites = 11 llr = 116 E-value = 2.0e+001 ******************************************************************************** -------------------------------------------------------------------------------- Motif CCAGCTAC MEME-5 Description -------------------------------------------------------------------------------- Simplified A ::a:::8: pos.-specific C aa::a:1a probability G :::a:::: matrix T :::::a1: bits 2.0 ****** * 1.8 ****** * 1.6 ****** * 1.4 ****** * Relative 1.2 ******** Entropy 1.0 ******** (15.2 bits) 0.8 ******** 0.6 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel CCAGCTAC consensus sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCAGCTAC MEME-5 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr18:23777285-23777365 4 1.44e-05 aat ccagctac tcggaaggct chr6:41985719-41985799 51 1.44e-05 gcctgtagtc ccagctac tcaggaggct chr17:41465264-41465344 48 1.44e-05 gcctgtagtc ccagctac ttgggaggct chr22:17002798-17002878 63 1.44e-05 atttgcagtc ccagctac tctggaggct chr13:91002487-91002567 12 1.44e-05 gcctgtaatt ccagctac tcaggaggct chr15:20864817-20864897 17 1.44e-05 ggctgtagtg ccagctac tggggacgct chr22:23140410-23140490 2 1.44e-05 c ccagctac ttgggaggct chr13:91838901-91838981 45 1.44e-05 acctgtaatc ccagctac tcgggaggct chr22:23373442-23373522 32 1.44e-05 gcctgtagtc ccagctac tcaggaggct chr22:23045675-23045755 47 4.31e-05 GCCTTTCCTT CCAGCTCC AGGTGGACTC chr11:129718332-12971841 33 4.31e-05 gcagcacagt ccagcttc ggctcggcat -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCAGCTAC MEME-5 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr18:23777285-23777365 1.4e-05 3_[+5]_69 chr6:41985719-41985799 1.4e-05 50_[+5]_22 chr17:41465264-41465344 1.4e-05 47_[+5]_25 chr22:17002798-17002878 1.4e-05 62_[+5]_10 chr13:91002487-91002567 1.4e-05 11_[+5]_61 chr15:20864817-20864897 1.4e-05 16_[+5]_56 chr22:23140410-23140490 1.4e-05 1_[+5]_71 chr13:91838901-91838981 1.4e-05 44_[+5]_28 chr22:23373442-23373522 1.4e-05 31_[+5]_41 chr22:23045675-23045755 4.3e-05 46_[+5]_26 chr11:129718332-12971841 4.3e-05 32_[+5]_40 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCAGCTAC MEME-5 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF CCAGCTAC width=8 seqs=11 chr18:23777285-23777365 ( 4) CCAGCTAC 1 chr6:41985719-41985799 ( 51) CCAGCTAC 1 chr17:41465264-41465344 ( 48) CCAGCTAC 1 chr22:17002798-17002878 ( 63) CCAGCTAC 1 chr13:91002487-91002567 ( 12) CCAGCTAC 1 chr15:20864817-20864897 ( 17) CCAGCTAC 1 chr22:23140410-23140490 ( 2) CCAGCTAC 1 chr13:91838901-91838981 ( 45) CCAGCTAC 1 chr22:23373442-23373522 ( 32) CCAGCTAC 1 chr22:23045675-23045755 ( 47) CCAGCTCC 1 chr11:129718332-12971841 ( 33) CCAGCTTC 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCAGCTAC MEME-5 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 11.0506 E= 2.0e+001 -1010 203 -1010 -1010 -1010 203 -1010 -1010 200 -1010 -1010 -1010 -1010 -1010 201 -1010 -1010 203 -1010 -1010 -1010 -1010 -1010 197 171 -143 -1010 -149 -1010 203 -1010 -1010 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCAGCTAC MEME-5 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 11 E= 2.0e+001 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.818182 0.090909 0.000000 0.090909 0.000000 1.000000 0.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCAGCTAC MEME-5 regular expression -------------------------------------------------------------------------------- CCAGCTAC -------------------------------------------------------------------------------- Time 19.72 secs. ******************************************************************************** ******************************************************************************** SUMMARY OF MOTIFS ******************************************************************************** -------------------------------------------------------------------------------- Combined block diagrams: non-overlapping sites with p-value < 0.0001 -------------------------------------------------------------------------------- SEQUENCE NAME COMBINED P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr22:22479813-22479893 7.37e-02 80 chr13:91972286-91972366 2.30e-01 80 chr13:81233439-81233519 1.25e-02 80 chr13:92290626-92290706 1.92e-03 65_[+1(1.50e-05)]_7 chr13:90721789-90721869 3.55e-01 80 chr13:91945665-91945745 5.11e-04 20_[+1(1.50e-05)]_52 chr7:54613831-54613911 1.00e+00 80 chr13:90902075-90902155 1.00e+00 80 chr3:39237615-39237695 4.66e-01 80 chr4:126236244-126236324 9.81e-01 80 chr22:23373442-23373522 5.45e-02 31_[+5(1.44e-05)]_41 chr16:21312734-21312814 4.97e-01 80 chr13:91743930-91744010 2.35e-03 33_[+1(4.41e-05)]_2_[+2(2.84e-05)]_\ 29 chr7:155585830-155585910 4.55e-03 1_[+3(1.41e-05)]_10_[+3(1.41e-05)]_\ 14_[+3(1.41e-05)]_10_[+3(1.41e-05)]_13 chr13:92359776-92359856 1.47e-03 56_[+1(4.41e-05)]_16 chr5:38348532-38348612 9.98e-01 80 chr15:26003844-26003924 1.37e-03 23_[+2(8.53e-05)]_49 chr7:154570414-154570494 1.67e-04 [+4(2.79e-05)]_43_[+4(2.79e-05)]_4_\ [+4(2.79e-05)]_1_[+4(2.79e-05)] chr8:58122681-58122761 4.82e-01 80 chr13:91863940-91864020 2.97e-01 80 chr13:91123997-91124077 2.18e-01 80 chr13:91345043-91345123 4.85e-05 10_[+1(1.50e-05)]_28_[+2(5.74e-05)]_\ 26 chr5:2593416-2593496 1.00e+00 80 chr7:121575526-121575606 9.99e-01 80 chr13:91838901-91838981 3.46e-02 44_[+5(1.44e-05)]_28 chr13:91352150-91352230 1.00e+00 80 chr13:91405545-91405625 9.71e-01 80 chr22:23287539-23287619 1.81e-01 80 chr13:91078714-91078794 1.82e-02 80 chr22:23118895-23118975 8.87e-02 80 chr6:142959964-142960044 1.00e+00 80 chr21:11138816-11138896 2.08e-02 14_[+2(5.74e-05)]_58 chr7:152995015-152995095 1.00e+00 80 chr13:81188979-81189059 1.71e-03 12_[+1(1.50e-05)]_29_[+2(5.74e-05)]_\ 23 chr22:23140410-23140490 5.30e-02 1_[+5(1.44e-05)]_71 chr10:52014963-52015043 9.72e-01 80 chr5:16574376-16574456 7.66e-01 80 chr7:131195783-131195863 2.78e-01 80 chr13:90870841-90870921 5.69e-02 19_[+2(2.84e-05)]_53 chr1:142967250-142967330 2.40e-01 80 chr13:92349459-92349539 2.17e-03 9_[+1(1.50e-05)]_29_[+2(5.74e-05)]_\ 26 chr13:91843359-91843439 3.25e-03 59_[+1(1.50e-05)]_13 chr13:81414872-81414952 9.99e-01 80 chr6:166121139-166121219 1.00e+00 80 chr10:47039406-47039486 3.22e-01 80 chr22:16918392-16918472 4.71e-01 80 chr22:17064444-17064524 8.13e-01 80 chr6:133089425-133089505 1.99e-01 80 chr11:66316453-66316533 1.64e-02 15_[+2(5.74e-05)]_57 chr11:129718332-12971841 4.35e-02 32_[+5(4.31e-05)]_40 chr22:23456195-23456275 4.22e-02 80 chr6:50654306-50654386 9.03e-04 14_[+4(7.04e-05)]_4_[+4(7.04e-05)]_\ 4_[+4(2.79e-05)]_17_[+4(1.41e-05)]_9 chr13:92241524-92241604 8.08e-01 80 chr1:172632753-172632833 9.72e-01 80 chr22:23381709-23381789 3.00e-03 63_[+2(2.84e-05)]_9 chr13:91489983-91490063 7.55e-04 80 chr22:17076162-17076242 1.96e-01 80 chr12:130498510-13049859 9.00e-01 80 chr13:91006720-91006800 1.94e-06 1_[+2(2.84e-05)]_55_[+3(1.41e-05)]_\ 8 chr1:185634126-185634206 7.66e-01 80 chr13:91916792-91916872 7.22e-01 80 chr13:92402145-92402225 2.42e-04 66_[+4(2.79e-05)]_6 chr21:11066751-11066831 2.26e-03 26_[+1(4.41e-05)]_2_[+2(2.84e-05)]_\ 36 chr10:44738462-44738542 5.27e-01 80 chr22:20946792-20946872 2.61e-01 67_[+1(4.41e-05)]_5 chr13:81310114-81310194 9.89e-01 80 chr22:29600971-29601051 3.09e-04 28_[+3(1.41e-05)]_20_[+3(1.41e-05)]_\ 16 chr22:23380440-23380520 7.06e-01 80 chr13:91261538-91261618 9.42e-01 80 chr7:144101420-144101500 1.34e-03 29_[+2(5.74e-05)]_43 chr6:6522486-6522566 1.29e-03 54_[+3(1.41e-05)]_18 chr16:74407456-74407536 4.41e-03 80 chr10:85631393-85631473 2.65e-02 80 chr2:105495453-105495533 3.00e-04 28_[+3(1.41e-05)]_16_[+3(5.75e-05)]_\ 20 chr13:91946610-91946690 1.68e-02 54_[+1(1.50e-05)]_18 chr13:81234172-81234252 8.86e-01 80 chr22:17024704-17024784 9.94e-01 80 chr22:17038777-17038857 4.74e-01 80 chr22:23231144-23231224 7.69e-01 80 chr13:114489366-11448944 8.90e-03 36_[+4(7.04e-05)]_13_[+4(7.04e-05)]_\ 15 chr2:30099393-30099473 1.00e+00 80 chr22:21416520-21416600 1.00e+00 80 chr22:23223472-23223552 7.71e-03 80 chr13:92317854-92317934 1.45e-04 11_[+2(5.74e-05)]_31_[+4(2.79e-05)]_\ 22 chr8:48116032-48116112 2.50e-04 26_[+3(1.41e-05)]_14_[+4(7.04e-05)]_\ [+3(5.75e-05)]_16 chr4:190527771-190527851 2.62e-02 80 chr22:23137420-23137500 4.18e-03 38_[+1(1.50e-05)]_34 chr7:141783521-141783601 1.00e+00 80 chr1:21835506-21835586 4.53e-02 80 chr13:92435779-92435859 2.32e-02 80 chr13:91202375-91202455 3.58e-02 72_[+2(2.84e-05)] chr2:53110099-53110179 1.00e+00 80 chr7:158309269-158309349 7.96e-01 80 chr5:6797628-6797708 1.02e-03 48_[+3(1.41e-05)]_3_[+3(5.75e-05)]_\ 13 chr16:26553640-26553720 5.43e-03 3_[+4(2.79e-05)]_19_[+4(2.79e-05)]_\ 34_[+4(7.04e-05)] chr5:142716-142796 5.28e-05 19_[+3(1.41e-05)]_6_[+4(5.60e-05)]_\ 39 chr11:287643-287723 8.17e-01 80 chr10:47124715-47124795 1.26e-01 80 chr7:159087368-159087448 9.98e-01 80 chr22:23279632-23279712 2.78e-01 80 chr13:91897778-91897858 7.76e-04 6_[+2(2.84e-05)]_66 chr13:91410955-91411035 5.48e-03 80 chr15:20864817-20864897 5.40e-02 16_[+5(1.44e-05)]_56 chr13:90655953-90656033 7.48e-03 70_[+3(8.56e-05)]_2 chr21:10139959-10140039 9.89e-01 80 chr13:92946935-92947015 9.99e-01 80 chr13:92084394-92084474 5.52e-01 80 chr6:11427602-11427682 6.73e-05 9_[+3(5.75e-05)]_13_[+4(5.60e-05)]_\ 7_[+3(1.41e-05)]_27 chr2:91778041-91778121 3.93e-01 80 chr8:144492720-144492800 1.00e+00 80 chr10:47014217-47014297 7.99e-01 80 chr13:92360445-92360525 9.94e-01 80 chr18:22962685-22962765 4.93e-01 80 chr7:126899568-126899648 9.02e-04 1_[+4(2.79e-05)]_7_[+4(2.79e-05)]_\ 19_[+4(2.79e-05)]_29 chr10:47092840-47092920 1.51e-02 80 chr22:21911833-21911913 3.25e-03 50_[+1(1.50e-05)]_22 chr12:42418113-42418193 5.01e-02 80 chr13:91002487-91002567 4.34e-02 11_[+5(1.44e-05)]_61 chr22:23379752-23379832 9.11e-04 80 chr6:41613403-41613483 4.61e-01 80 chr13:92365158-92365238 3.54e-01 80 chr6:141494261-141494341 9.66e-01 80 chr13:92314455-92314535 7.25e-01 80 chr13:81268515-81268595 2.66e-01 80 chr13:92373444-92373524 1.60e-03 16_[+1(1.50e-05)]_56 chr7:154140678-154140758 1.00e+00 80 chr22:23405668-23405748 9.08e-03 80 chr13:81371796-81371876 9.99e-01 80 chr22:23101566-23101646 1.46e-01 80 chr13:90561372-90561452 3.67e-03 41_[+1(1.50e-05)]_31 chr22:16984493-16984573 2.17e-03 8_[+1(1.50e-05)]_29_[+2(5.74e-05)]_\ 27 chr10:35992934-35993014 8.70e-05 8_[+4(1.41e-05)]_49_[+4(1.41e-05)]_\ 7 chr22:23000045-23000125 1.30e-02 4_[+3(9.99e-05)]_68 chr11:132409713-13240979 1.00e+00 80 chr22:17002798-17002878 1.28e-02 62_[+5(1.44e-05)]_10 chr13:81369545-81369625 4.55e-02 32_[+2(2.84e-05)]_40 chr13:91635305-91635385 7.02e-02 [+3(8.56e-05)]_72 chr7:112057278-112057358 9.01e-02 80 chr5:33672175-33672255 1.26e-04 3_[+3(5.75e-05)]_2_[+3(1.41e-05)]_4_\ [+3(4.28e-05)]_6_[+3(4.28e-05)]_2_[+3(1.41e-05)]_2_[+3(5.75e-05)]_2_\ [+3(1.41e-05)]_3 chr13:91393563-91393643 2.94e-03 38_[+1(1.50e-05)]_34 chr13:90595462-90595542 9.35e-01 80 chr3:25627578-25627658 5.68e-02 80 chr12:129873946-12987402 3.63e-05 [+4(5.60e-05)]_53_[+1(2.97e-05)]_2_\ [+4(1.41e-05)]_1 chr1:236156693-236156773 9.99e-01 80 chr13:91887096-91887176 4.76e-01 80 chr13:91522042-91522122 2.49e-01 80 chr13:91315407-91315487 2.17e-03 18_[+1(1.50e-05)]_1_[+1(8.85e-05)]_\ 20_[+2(5.74e-05)]_17 chr22:23465430-23465510 6.15e-01 80 chr7:87860120-87860200 3.12e-04 6_[+4(5.60e-05)]_66 chr7:68489467-68489547 2.81e-03 39_[+1(1.50e-05)]_33 chr22:23107497-23107577 7.46e-01 80 chr11:3458817-3458897 4.35e-04 47_[+1(8.85e-05)]_25 chr5:17146725-17146805 1.93e-01 45_[+2(5.74e-05)]_27 chr14:19613018-19613098 6.59e-03 9_[+3(2.84e-05)]_63 chr2:149859077-149859157 5.18e-05 70_[+3(4.28e-05)]_2 chr3:13789228-13789308 1.20e-03 1_[+3(2.84e-05)]_6_[+3(1.41e-05)]_\ 18_[+3(9.99e-05)]_2_[+3(1.41e-05)]_2_[+3(1.41e-05)]_[+3(1.41e-05)]_3 chr13:92129950-92130030 5.07e-01 80 chr7:98375324-98375404 9.95e-01 80 chr9:66455314-66455394 9.56e-01 80 chr7:56395185-56395265 9.97e-01 80 chr22:23354310-23354390 6.13e-01 80 chr1:27963210-27963290 3.95e-01 80 chr10:84220969-84221049 2.96e-04 4_[+4(7.04e-05)]_1_[+4(2.79e-05)]_1_\ [+4(2.79e-05)]_7_[+4(2.79e-05)]_7_[+4(7.04e-05)]_20 chr8:14718003-14718083 7.62e-01 80 chr7:136575606-136575686 1.00e+00 80 chr17:41465264-41465344 2.71e-02 47_[+5(1.44e-05)]_25 chr18:56449061-56449141 1.00e+00 80 chr10:17055274-17055354 4.53e-01 80 chr7:134415857-134415937 3.00e-02 13_[+2(5.74e-05)]_59 chr7:111397014-111397094 9.68e-01 80 chr21:34563697-34563777 1.00e+00 80 chr13:91546393-91546473 9.97e-01 80 chr7:156241768-156241848 1.00e+00 80 chr13:91594632-91594712 1.70e-03 7_[+3(5.75e-05)]_42_[+4(1.41e-05)]_\ 15 chr7:148028688-148028768 1.00e+00 80 chr21:44919729-44919809 8.67e-04 38_[+3(1.41e-05)]_34 chr16:4261625-4261705 9.98e-01 80 chr2:149877635-149877715 8.23e-04 13_[+1(1.50e-05)]_59 chr4:178171342-178171422 1.08e-01 80 chr22:23117322-23117402 2.40e-02 80 chr11:65669778-65669858 6.49e-02 80 chr1:209313371-209313451 1.00e+00 80 chr15:20545090-20545170 9.97e-01 80 chr22:23423154-23423234 2.56e-01 80 chr21:11110658-11110738 1.00e+00 80 chr22:22557749-22557829 5.63e-01 80 chr22:22795723-22795803 8.92e-03 16_[+2(2.84e-05)]_56 chr5:131191272-131191352 7.23e-01 80 chr11:131893590-13189367 1.00e+00 80 chr2:91763990-91764070 8.87e-01 80 chr18:24229729-24229809 9.02e-01 80 chr6:41985719-41985799 2.71e-02 50_[+5(1.44e-05)]_22 chr8:58118551-58118631 9.91e-01 80 chr1:175734657-175734737 1.00e+00 80 chr13:92370462-92370542 3.87e-02 80 chr16:5161130-5161210 1.36e-04 69_[+1(8.85e-05)]_3 chr9:131006434-131006514 9.99e-01 80 chr10:59305406-59305486 7.71e-01 80 chr7:112337772-112337852 5.10e-02 80 chr22:23259758-23259838 5.85e-01 80 chr1:16484330-16484410 1.00e+00 80 chr13:91533260-91533340 7.16e-02 80 chr13:91358209-91358289 2.36e-03 50_[+1(4.41e-05)]_2_[+2(2.84e-05)]_\ 12 chr1:209568841-209568921 4.58e-01 80 chr1:111264955-111265035 1.00e+00 80 chr2:91764649-91764729 7.59e-01 80 chr10:80664896-80664976 1.80e-02 5_[+1(8.85e-05)]_67 chr18:23777285-23777365 8.37e-02 3_[+5(1.44e-05)]_69 chr13:90986620-90986700 5.54e-05 1_[+1(1.50e-05)]_29_[+2(5.74e-05)]_\ 34 chr1:228107442-228107522 1.59e-02 45_[+3(4.28e-05)]_1_[+3(4.28e-05)]_\ 18 chr1:164444206-164444286 1.00e+00 80 chr4:3969101-3969181 2.31e-01 80 chr5:38290687-38290767 1.11e-01 80 chr7:152761637-152761717 3.22e-02 80 chr3:149939683-149939763 7.84e-01 80 chr22:22610615-22610695 1.11e-04 24_[+3(2.84e-05)]_20_[+3(1.41e-05)]_\ 20 chr13:91831225-91831305 7.49e-03 17_[+1(1.50e-05)]_55 chr1:17248230-17248310 2.11e-02 65_[+2(5.74e-05)]_7 chr13:91148303-91148383 5.53e-02 80 chr13:81258728-81258808 7.89e-01 80 chr13:91139884-91139964 2.20e-03 52_[+1(4.41e-05)]_2_[+2(2.84e-05)]_\ 10 chr6:99293753-99293833 2.57e-01 80 chr7:140861635-140861715 9.98e-01 80 chr16:49674216-49674296 1.73e-05 13_[+3(1.41e-05)]_8_[+4(7.04e-05)]_\ 8_[+3(4.28e-05)]_4_[+3(4.28e-05)]_15 chr4:184277492-184277572 4.98e-02 80 chr15:22520730-22520810 2.68e-02 80 chr22:23375508-23375588 1.03e-02 80 chr6:21326072-21326152 3.38e-03 70_[+1(2.97e-05)]_2 chr4:144860890-144860970 1.08e-01 80 chr22:23017159-23017239 4.31e-05 2_[+3(1.41e-05)]_[+3(1.41e-05)]_\ [+3(1.41e-05)]_54 chr13:81413389-81413469 1.18e-01 80 chr20:43941974-43942054 5.61e-03 80 chr6:160956512-160956592 1.00e+00 80 chr21:40497777-40497857 1.40e-04 5_[+3(1.41e-05)]_11_[+4(5.60e-05)]_\ 37_[+3(2.84e-05)]_3 chr18:6042341-6042421 1.19e-05 5_[+3(1.41e-05)]_8_[+3(1.41e-05)]_\ [+3(2.84e-05)]_2_[+3(1.41e-05)]_19_[+2(5.74e-05)]_6 chr13:90946140-90946220 1.42e-02 45_[+2(2.84e-05)]_27 chr13:90914394-90914474 4.63e-03 41_[+4(9.80e-05)]_31 chr22:23364716-23364796 4.01e-01 80 chr13:91914670-91914750 3.83e-02 80 chr6:21924989-21925069 1.00e+00 80 chr7:13199350-13199430 1.00e+00 80 chr22:23416798-23416878 9.96e-01 80 chr21:46313799-46313879 1.68e-01 80 chr22:23045675-23045755 6.52e-06 27_[+2(5.74e-05)]_11_[+5(4.31e-05)]_\ 26 chr22:23440413-23440493 1.05e-02 26_[+2(5.74e-05)]_46 chr1:19152331-19152411 1.85e-04 6_[+1(5.81e-05)]_23_[+4(2.79e-05)]_\ 35 chr13:91825681-91825761 3.76e-02 80 chr22:17003686-17003766 2.97e-01 80 chr22:23458653-23458733 2.86e-01 80 chr5:168250272-168250352 4.22e-01 80 -------------------------------------------------------------------------------- ******************************************************************************** ******************************************************************************** Stopped because requested number of motifs (5) found. ******************************************************************************** CPU: c22n05.farnam.hpc.yale.internal ********************************************************************************