******************************************************************************** MEME - Motif discovery tool ******************************************************************************** MEME version 5.3.3 (Release date: Sun Feb 7 15:39:52 2021 -0800) For further information on how to interpret these results please access https://meme-suite.org/meme. To get a copy of the MEME Suite software please access https://meme-suite.org. ******************************************************************************** ******************************************************************************** REFERENCE ******************************************************************************** If you use this program in your research, please cite: Timothy L. Bailey and Charles Elkan, "Fitting a mixture model by expectation maximization to discover motifs in biopolymers", Proceedings of the Second International Conference on Intelligent Systems for Molecular Biology, pp. 28-36, AAAI Press, Menlo Park, California, 1994. ******************************************************************************** ******************************************************************************** TRAINING SET ******************************************************************************** PRIMARY SEQUENCES= ../result/final_prediction/K562/fasta/RankLinear0.6_40/KDM1A.fasta CONTROL SEQUENCES= --none-- ALPHABET= ACGT Sequence name Weight Length Sequence name Weight Length ------------- ------ ------ ------------- ------ ------ chr21:47012875-47012955 1.0000 80 chr7:102793856-102793936 1.0000 80 chr2:192713667-192713747 1.0000 80 chr21:44353030-44353110 1.0000 80 chr21:44369385-44369465 1.0000 80 chr3:194295753-194295833 1.0000 80 chr11:64995501-64995581 1.0000 80 chr1:17035330-17035410 1.0000 80 chr17:25615963-25616043 1.0000 80 chr14:104305411-10430549 1.0000 80 chr11:926619-926699 1.0000 80 chr1:1353301-1353381 1.0000 80 chr17:74249137-74249217 1.0000 80 chr6:150167638-150167718 1.0000 80 chr18:19612513-19612593 1.0000 80 chr7:77344417-77344497 1.0000 80 chr3:31586264-31586344 1.0000 80 chr18:73552-73632 1.0000 80 chr7:99845649-99845729 1.0000 80 chr17:42084540-42084620 1.0000 80 chr11:96037278-96037358 1.0000 80 chr12:122634812-12263489 1.0000 80 chr12:32260753-32260833 1.0000 80 chr16:14579255-14579335 1.0000 80 chr9:141044417-141044497 1.0000 80 chr11:117720896-11772097 1.0000 80 chr12:123002517-12300259 1.0000 80 chr19:17826814-17826894 1.0000 80 chr15:66080172-66080252 1.0000 80 chr1:167833313-167833393 1.0000 80 chr6:161827816-161827896 1.0000 80 chr7:73258545-73258625 1.0000 80 chr10:120940549-12094062 1.0000 80 chr7:45027718-45027798 1.0000 80 chr1:154077015-154077095 1.0000 80 chr8:27192681-27192761 1.0000 80 chr6:32054607-32054687 1.0000 80 chr12:24102311-24102391 1.0000 80 chr2:121049641-121049721 1.0000 80 chr6:142433779-142433859 1.0000 80 chr11:61876569-61876649 1.0000 80 chr6:33241784-33241864 1.0000 80 chr13:114919164-11491924 1.0000 80 chr7:129595299-129595379 1.0000 80 chr7:124702161-124702241 1.0000 80 chr12:109217674-10921775 1.0000 80 chr11:85960534-85960614 1.0000 80 chr9:116160609-116160689 1.0000 80 chr11:66846320-66846400 1.0000 80 chr4:79572762-79572842 1.0000 80 chr20:37089049-37089129 1.0000 80 chr10:1096180-1096260 1.0000 80 chr19:1018594-1018674 1.0000 80 chr7:139975948-139976028 1.0000 80 chr1:93914783-93914863 1.0000 80 chr1:28504836-28504916 1.0000 80 chr3:196347293-196347373 1.0000 80 chr1:245498286-245498366 1.0000 80 chr1:23886380-23886460 1.0000 80 chr1:159834208-159834288 1.0000 80 chr16:67523149-67523229 1.0000 80 chr2:27201321-27201401 1.0000 80 chr16:2844641-2844721 1.0000 80 chr17:35425195-35425275 1.0000 80 chr6:27562303-27562383 1.0000 80 chr2:37465461-37465541 1.0000 80 chr1:1828723-1828803 1.0000 80 chrX:118926503-118926583 1.0000 80 chr4:108913520-108913600 1.0000 80 chr17:38296201-38296281 1.0000 80 chr1:155367038-155367118 1.0000 80 chr2:191471946-191472026 1.0000 80 chr1:6499488-6499568 1.0000 80 chr12:117627569-11762764 1.0000 80 chr5:173043106-173043186 1.0000 80 chr16:89231041-89231121 1.0000 80 chr9:114364073-114364153 1.0000 80 chr1:211861325-211861405 1.0000 80 chr22:40002806-40002886 1.0000 80 chr2:120916435-120916515 1.0000 80 chr7:30280119-30280199 1.0000 80 chr12:31910162-31910242 1.0000 80 chr17:62530046-62530126 1.0000 80 chr1:231158439-231158519 1.0000 80 chr1:211854340-211854420 1.0000 80 chr6:30910553-30910633 1.0000 80 chr10:52153185-52153265 1.0000 80 chr1:9034143-9034223 1.0000 80 chr22:29811052-29811132 1.0000 80 chr5:86447525-86447605 1.0000 80 chr6:135485649-135485729 1.0000 80 chr22:40895291-40895371 1.0000 80 chr10:94404161-94404241 1.0000 80 chrX:117859006-117859086 1.0000 80 chr19:39794157-39794237 1.0000 80 chr12:4430042-4430122 1.0000 80 chr6:27204148-27204228 1.0000 80 chr19:45657982-45658062 1.0000 80 chr1:148556813-148556893 1.0000 80 chr12:1281025-1281105 1.0000 80 chr7:100437717-100437797 1.0000 80 chr9:132806039-132806119 1.0000 80 chr3:50288758-50288838 1.0000 80 chr19:10974189-10974269 1.0000 80 chr9:102864053-102864133 1.0000 80 chr1:94371412-94371492 1.0000 80 chr1:111019953-111020033 1.0000 80 chr1:61547423-61547503 1.0000 80 chr12:112621192-11262127 1.0000 80 chr2:97563445-97563525 1.0000 80 chr8:42158042-42158122 1.0000 80 chr1:159046749-159046829 1.0000 80 chr6:105123218-105123298 1.0000 80 chr2:111920529-111920609 1.0000 80 chr7:32818935-32819015 1.0000 80 chr5:10487806-10487886 1.0000 80 chr1:109692017-109692097 1.0000 80 chr6:136572714-136572794 1.0000 80 chr1:181687324-181687404 1.0000 80 chr12:133712490-13371257 1.0000 80 chr4:110660820-110660900 1.0000 80 chr1:211787468-211787548 1.0000 80 chr5:138524357-138524437 1.0000 80 chr17:7530495-7530575 1.0000 80 chr18:42304463-42304543 1.0000 80 chr2:161979964-161980044 1.0000 80 chr4:164101370-164101450 1.0000 80 chrX:48510747-48510827 1.0000 80 chr1:23952622-23952702 1.0000 80 chr5:173311825-173311905 1.0000 80 chrX:154083658-154083738 1.0000 80 chr1:228272083-228272163 1.0000 80 chr6:36099635-36099715 1.0000 80 chr18:3639531-3639611 1.0000 80 chr5:149995643-149995723 1.0000 80 chr8:30586967-30587047 1.0000 80 chr17:46949153-46949233 1.0000 80 chr17:26793839-26793919 1.0000 80 chr22:20827622-20827702 1.0000 80 chr20:36155043-36155123 1.0000 80 chr1:203648538-203648618 1.0000 80 chr4:129181203-129181283 1.0000 80 chr4:39559996-39560076 1.0000 80 chr11:10428714-10428794 1.0000 80 chr6:170166013-170166093 1.0000 80 chr5:171711726-171711806 1.0000 80 chr1:116901832-116901912 1.0000 80 chr21:45277493-45277573 1.0000 80 chr7:30336136-30336216 1.0000 80 chr2:152991156-152991236 1.0000 80 chr9:101089348-101089428 1.0000 80 chr13:47695623-47695703 1.0000 80 chr7:45030473-45030553 1.0000 80 chr11:129830235-12983031 1.0000 80 chr12:10902908-10902988 1.0000 80 chr3:58457174-58457254 1.0000 80 chr19:50878394-50878474 1.0000 80 chr5:78054083-78054163 1.0000 80 chr1:228352356-228352436 1.0000 80 chr1:65744880-65744960 1.0000 80 chr3:10187531-10187611 1.0000 80 chr7:151039260-151039340 1.0000 80 chr22:32225558-32225638 1.0000 80 chr17:16176891-16176971 1.0000 80 chr2:240187008-240187088 1.0000 80 chr4:111080125-111080205 1.0000 80 chr8:8871094-8871174 1.0000 80 chr3:196170804-196170884 1.0000 80 chr17:73402156-73402236 1.0000 80 chr1:205145175-205145255 1.0000 80 chr9:97519492-97519572 1.0000 80 chr16:21623470-21623550 1.0000 80 chr4:128454711-128454791 1.0000 80 chr22:29666573-29666653 1.0000 80 chrX:118606675-118606755 1.0000 80 chr12:48214262-48214342 1.0000 80 chr6:150173356-150173436 1.0000 80 chr8:126935379-126935459 1.0000 80 chr20:20391568-20391648 1.0000 80 chr3:51573633-51573713 1.0000 80 chr15:72765340-72765420 1.0000 80 chr11:44564062-44564142 1.0000 80 chr11:13132646-13132726 1.0000 80 chr1:43325230-43325310 1.0000 80 chr5:159546947-159547027 1.0000 80 chr11:72297693-72297773 1.0000 80 chr18:323471-323551 1.0000 80 chr1:113216395-113216475 1.0000 80 chr13:41255672-41255752 1.0000 80 chr10:52288116-52288196 1.0000 80 chr1:116963178-116963258 1.0000 80 chr17:43371031-43371111 1.0000 80 chr5:141742543-141742623 1.0000 80 chr9:75058384-75058464 1.0000 80 chr1:206287921-206288001 1.0000 80 chr1:20848880-20848960 1.0000 80 chr7:97847760-97847840 1.0000 80 chr1:41704238-41704318 1.0000 80 chr7:134278841-134278921 1.0000 80 chr2:54799552-54799632 1.0000 80 chr7:102624231-102624311 1.0000 80 chr20:37499554-37499634 1.0000 80 chr8:22775933-22776013 1.0000 80 chr1:29107974-29108054 1.0000 80 chr1:150228495-150228575 1.0000 80 chr15:48847486-48847566 1.0000 80 chr1:44509958-44510038 1.0000 80 chr19:34761001-34761081 1.0000 80 chrX:118611819-118611899 1.0000 80 chr8:17987766-17987846 1.0000 80 chr12:96765330-96765410 1.0000 80 chr11:47536999-47537079 1.0000 80 chr16:30560846-30560926 1.0000 80 chr1:9679088-9679168 1.0000 80 chr1:46379133-46379213 1.0000 80 chr11:118444130-11844421 1.0000 80 chr10:97501762-97501842 1.0000 80 chr8:23204703-23204783 1.0000 80 chr9:36102390-36102470 1.0000 80 chr1:196407719-196407799 1.0000 80 chr8:143808020-143808100 1.0000 80 chr4:48700513-48700593 1.0000 80 chr7:99160684-99160764 1.0000 80 chr21:18826682-18826762 1.0000 80 chr9:33151199-33151279 1.0000 80 chr19:35865995-35866075 1.0000 80 chr15:77838521-77838601 1.0000 80 chr7:30510018-30510098 1.0000 80 chr12:93571613-93571693 1.0000 80 chr8:61705458-61705538 1.0000 80 chr7:123178417-123178497 1.0000 80 chr19:54605751-54605831 1.0000 80 chr19:46265748-46265828 1.0000 80 chr20:5718077-5718157 1.0000 80 chr12:516020-516100 1.0000 80 chr10:11799654-11799734 1.0000 80 chr2:48731961-48732041 1.0000 80 chr1:114911364-114911444 1.0000 80 chr12:7394158-7394238 1.0000 80 chr10:121186926-12118700 1.0000 80 chr12:42838649-42838729 1.0000 80 chr19:13162541-13162621 1.0000 80 chr1:40515082-40515162 1.0000 80 chr22:50971954-50972034 1.0000 80 chr10:51576023-51576103 1.0000 80 chr6:90007837-90007917 1.0000 80 chr1:247500632-247500712 1.0000 80 chr5:66502917-66502997 1.0000 80 chr18:12337043-12337123 1.0000 80 chr12:113817217-11381729 1.0000 80 ******************************************************************************** ******************************************************************************** COMMAND LINE SUMMARY ******************************************************************************** This information can also be useful in the event you wish to report a problem with the MEME software. command: meme -oc ../result/final_prediction/K562/inference_raw/MEME/RankLinear0.6_40_KDM1A/ -dna -nmotifs 5 -w 8 -maxsize 250000 -nostatus ../result/final_prediction/K562/fasta/RankLinear0.6_40/KDM1A.fasta model: mod= zoops nmotifs= 5 evt= inf objective function: em= E-value of product of p-values starts= E-value of product of p-values strands: + width: minw= 8 maxw= 8 nsites: minsites= 2 maxsites= 250 wnsites= 0.8 theta: spmap= uni spfuzz= 0.5 em: prior= dirichlet b= 0.01 maxiter= 50 distance= 1e-05 trim: wg= 11 ws= 1 endgaps= yes data: n= 20000 N= 250 sample: seed= 0 hsfrac= 0 searchsize= 20000 norand= no csites= 1000 Letter frequencies in dataset: A 0.265 C 0.23 G 0.228 T 0.277 Background letter frequencies (from file dataset with add-one prior applied): A 0.265 C 0.23 G 0.228 T 0.277 Background model order: 0 ******************************************************************************** ******************************************************************************** MOTIF AATCWCWG MEME-1 width = 8 sites = 112 llr = 854 E-value = 4.2e-067 ******************************************************************************** -------------------------------------------------------------------------------- Motif AATCWCWG MEME-1 Description -------------------------------------------------------------------------------- Simplified A a9::4:5: pos.-specific C :::a17:: probability G :1:::3:8 matrix T ::a:5:42 bits 2.1 * 1.9 * * 1.7 * ** 1.5 **** * Relative 1.3 **** * Entropy 1.1 **** * * (11.0 bits) 0.9 **** * * 0.6 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel AATCTCAG consensus AGT sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AATCWCWG MEME-1 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr2:48731961-48732041 51 1.72e-05 tcatgcctgt aatctcag ctactcagga chr12:93571613-93571693 6 1.72e-05 tttct aatctcag gcatttcaag chr7:99160684-99160764 54 1.72e-05 GGGCAGCAGA AATCTCAG ATGTTTACCC chr12:96765330-96765410 59 1.72e-05 tgaccaacat aatctcag ctactcagga chr1:150228495-150228575 16 1.72e-05 TGGAAATCGG AATCTCAG CTCAGCGCTC chr7:102624231-102624311 59 1.72e-05 gattttcagg aatctcag ccctgtggct chr5:141742543-141742623 53 1.72e-05 GTTCTTGAGA AATCTCAG AAACAGTAAC chr18:323471-323551 34 1.72e-05 ATGAGTTCAA AATCTCAG CCTGTGACAA chr4:111080125-111080205 42 1.72e-05 ACAAAATCTG AATCTCAG CTCTTACTTT chr1:116901832-116901912 28 1.72e-05 aatccctctg aatctcag cttcctcatt chr18:42304463-42304543 57 1.72e-05 CAGATAAGCA AATCTCAG AAGCACAGCT chr3:50288758-50288838 18 1.72e-05 gaatgcagca aatctcag tacCAGCTAA chr19:45657982-45658062 43 1.72e-05 tcacgcctgt aatctcag cactttttgg chrX:118926503-118926583 10 1.72e-05 ggcgcctgt aatctcag ctactgcggg chr4:79572762-79572842 15 1.72e-05 acacacctgt aatctcag ctactcaaga chr6:142433779-142433859 33 1.72e-05 ACATTTTGTA AATCTCAG TTAAAAATCA chr7:73258545-73258625 3 1.72e-05 tc aatctcag ctcatgcaac chr15:66080172-66080252 14 1.72e-05 ttacctttgt aatctcag taactagcaa chr12:123002517-12300259 39 1.72e-05 AGTGGTTAAA AATCTCAg ctgggcagag chr7:99845649-99845729 13 1.72e-05 aggtgcctgt aatctcag ctactccgga chr12:7394158-7394238 57 3.37e-05 TGACCACAAA AATCACAG GAGTGTTGAG chr19:46265748-46265828 1 3.37e-05 . aatcacag ctcactgcaa chr13:41255672-41255752 64 3.37e-05 GGCCTCTTGG AATCACAG TTGATAATG chr4:39559996-39560076 18 3.37e-05 ttgcctgaaa aatcacag ctgctgcagc chr18:3639531-3639611 17 3.37e-05 TTTGTATGGG AATCACAG CCCATTGGCT chr12:122634812-12263489 22 3.37e-05 AAAGCAACAA AATCACAG TTAATGAGAA chr20:5718077-5718157 7 5.17e-05 GCTATT AATCTCTG AGATGATTCT chr1:20848880-20848960 59 5.17e-05 GGCAGCCTAA AATCTCTG GGATTTTCCT chr4:128454711-128454791 38 5.17e-05 AAGCAAATAA AATCTCTG TTTCACAGCA chr12:10902908-10902988 50 5.17e-05 GGTTCCAGTA AATCTCTG CTGCTCTTGT chr9:132806039-132806119 9 5.17e-05 TGATTTCC AATCTCTG AAACCAGTGA chr9:116160609-116160689 27 5.17e-05 TCCCACAAAC AATCTCTG TTGTTTTCTG chr18:73552-73632 24 5.17e-05 AGCTCTGGGG AATCTCTG AAAATCAGCG chr14:104305411-10430549 18 5.17e-05 tgctcaccgc aatctctg cctcccaggt chr17:25615963-25616043 27 5.17e-05 tgcttactgc aatctctg cctcccaggc chr11:13132646-13132726 42 6.89e-05 TTGGAGTCTG AATCACTG CTTACCCATC chr12:48214262-48214342 31 6.89e-05 ATCTGATTTG AATCACTG CCCAGCCCTC chr17:73402156-73402236 57 6.89e-05 TCATTGATTG AATCACTG CAGAGTTTGT chr1:228272083-228272163 24 6.89e-05 AATAAATCCA AATCACTG CAGCAGTAGG chr1:94371412-94371492 40 6.89e-05 ggcaatctga aaTCACTG CCTTATTAGA chr10:52153185-52153265 6 6.89e-05 GCACA AATCACTG CCTGTCACTT chr7:139975948-139976028 61 6.89e-05 GGAGAAGAAA AATCACTG AGAAATCTCA chr6:32054607-32054687 56 6.89e-05 TCAGAACGGG AATCACTG TTTTCAATTC chr1:154077015-154077095 27 6.89e-05 tgcattccac aatcactg cactccccca chr3:194295753-194295833 38 6.89e-05 tggggttgaa aatcactg CGTTATCTCA chr7:45030473-45030553 41 8.60e-05 gtaggcctct aatctgag ccactccaca chr4:110660820-110660900 1 8.60e-05 . aatctgag gttctaggaa chr1:206287921-206288001 11 1.02e-04 tcaaaaccaa aatcagag tatccagaaa chr17:16176891-16176971 7 1.02e-04 gtgaga aatcagag tcagaaaaaa chr5:138524357-138524437 10 1.02e-04 GAGCATACA AATCAGAG GAAAGCAGTG chr17:35425195-35425275 45 1.02e-04 TGTGGCTTGA AATCAGAG CTCTGCTGGG chr20:37089049-37089129 44 1.02e-04 actccgaggg aatcagag ccccagtaac chr1:1353301-1353381 25 1.02e-04 tcaaaaccaa aatcagag tatccagaaa chr21:44369385-44369465 17 1.02e-04 tcaaaaccaa aatcagag taaccagaaa chr19:13162541-13162621 55 1.20e-04 CAGCGATACT AATCTGTG TCAACAGGCC chr15:48847486-48847566 69 1.20e-04 ACAGAGCAGA AATCTGTG GAGA chr19:10974189-10974269 73 1.20e-04 TCTGTGTCAC AATCTGTG chr12:1281025-1281105 59 1.20e-04 GATGTCAATA AATCTGTG CCAATGTGGA chr12:117627569-11762764 73 1.20e-04 gccacgctga aatctgtg chr11:117720896-11772097 59 1.20e-04 tcttttgcaa aatctgtg tcacagtgat chr6:150173356-150173436 39 1.37e-04 GTAGAGTACA AATCAGTG CCTCCTTACC chr6:27204148-27204228 71 1.37e-04 TTTGAAAACC AATCAGTG TC chr12:4430042-4430122 40 1.37e-04 AACAACCACA AATCAGTG CGCCGGCTTC chr19:39794157-39794237 22 1.37e-04 tggatgcggc aatcagtg caggggttgc chr2:120916435-120916515 45 1.37e-04 aaggatacaa aatcagtg tacaaaaatc chr11:926619-926699 4 1.37e-04 GGA AATCAGTG TCTTCCCAGG chr8:23204703-23204783 46 1.52e-04 gcatgcctgt aatcccag cgactcagga chr21:45277493-45277573 29 1.52e-04 tcatgcctgt aatcccag cactttggga chr11:66846320-66846400 55 1.52e-04 tcacgcctgt aatcccag cactttggaa chr7:77344417-77344497 51 1.52e-04 atgtgcctgt aatcccag ctacttggga chr10:51576023-51576103 40 1.87e-04 GTAACTTTTA AATCTCAT CCTACATTCT chr13:47695623-47695703 15 1.87e-04 TTCTATGGTA AATCCCTG tcatctcatt chr4:129181203-129181283 51 1.87e-04 gcactgtgaa aatccctg tcctgttctg chrX:154083658-154083738 43 1.87e-04 tcaaatgcca aatctcat cctgtgacta chr1:111019953-111020033 17 1.87e-04 gactcagttc aatccctg gttctatttc chr11:64995501-64995581 50 1.87e-04 cccagattta aatctcat gttattagat chr12:113817217-11381729 41 2.44e-04 agcctttctg agtctcag attgccttat chr19:35865995-35866075 6 2.44e-04 GGTCA AGTCTCAG CTTACAGGGG chr7:97847760-97847840 73 2.44e-04 agttcaggaa agtctcag chr17:26793839-26793919 70 2.44e-04 AACAGCACTT AATCTCTT GGG chr6:105123218-105123298 21 2.44e-04 caacttcagc agtctcag catacaaaat chr2:97563445-97563525 45 2.44e-04 cactcccagt aatctctt ctcaacacag chr6:90007837-90007917 50 2.79e-04 AAGGGAGATG AGTCACAG GCCTGTAATC chr12:516020-516100 4 2.79e-04 gag aatcactt gaatcctgga chr1:9679088-9679168 15 2.79e-04 aatatccgca aatcactt ccactaaatc chr1:41704238-41704318 45 2.79e-04 catcatcctc aatcactt cactctctac chr2:152991156-152991236 9 2.79e-04 cctggctc aatcactt actagacaca chr4:164101370-164101450 2 2.79e-04 a aatcactt ctcttctaac chr2:192713667-192713747 11 2.79e-04 TTCACATTAT AATCACTT CACCCTGATT chr16:30560846-30560926 51 3.10e-04 tacaggcatg agtcactg cctggcctga chr19:50878394-50878474 26 3.24e-04 gcaatggcgc aatctcgg ctcaccgcaa chr6:36099635-36099715 65 3.24e-04 ctggggtttc aatctcgg cagcgagg chr9:141044417-141044497 37 3.53e-04 AAATTTCCAA AATCACGG CCTGGAAAAA chr12:133712490-13371257 14 4.03e-04 TACTCTCCGT AACCTCAG CTTATCTTTT chr6:33241784-33241864 30 4.03e-04 atctcactgc aacctcag cctcccaagt chr9:36102390-36102470 46 5.07e-04 TGATTCTATC AGTCTGAG GAGGTACCAA chr7:30336136-30336216 45 5.07e-04 AACACCCTTC AGTCTGAG AGCCCTGAAG chr9:114364073-114364153 10 5.07e-04 GTCAAACAA AATCTGTT TCCCAAACTT chr1:28504836-28504916 15 5.07e-04 agctcactgc aacctctg cctcccactt chr10:120940549-12094062 6 5.07e-04 actgc aacctctg cctcccagat chr3:196170804-196170884 20 5.75e-04 ttactactca aatcagtt tcccctagca chr7:151039260-151039340 43 5.75e-04 ATTTATTTGC AATCAAAG CCAGATTTTC chr1:211787468-211787548 62 5.75e-04 acagatgaag aatcaaag ctgagagtga chr5:173043106-173043186 29 5.75e-04 GGCTTTCGAA AATCAAAG CTGCCACCCG chr1:6499488-6499568 18 5.75e-04 caaaggtcaa aatcagtt atggtcaacc chr7:124702161-124702241 44 5.75e-04 AATTTTTTAG AGTCAGAG TTGAGATTGA chr12:24102311-24102391 7 5.75e-04 TTTGCA AATCAGTT CAGTTTGGTC chr17:42084540-42084620 5 6.11e-04 GACA AATCTATG CAGACCACTG chr15:72765340-72765420 23 6.92e-04 TTTATCAACA AATCAGGG GTTTTGATTT chr7:45027718-45027798 17 6.92e-04 acagtataca aatcccat acttcactaa chr3:58457174-58457254 34 7.37e-04 TTAAGAATGA AACCTGAG CTGGCTTCTT chr18:12337043-12337123 67 8.27e-04 TTAATCATTC AGTCACAT TCCTAA -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AATCWCWG MEME-1 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr2:48731961-48732041 1.7e-05 50_[+1]_22 chr12:93571613-93571693 1.7e-05 5_[+1]_67 chr7:99160684-99160764 1.7e-05 53_[+1]_19 chr12:96765330-96765410 1.7e-05 58_[+1]_14 chr1:150228495-150228575 1.7e-05 15_[+1]_57 chr7:102624231-102624311 1.7e-05 58_[+1]_14 chr5:141742543-141742623 1.7e-05 52_[+1]_20 chr18:323471-323551 1.7e-05 33_[+1]_39 chr4:111080125-111080205 1.7e-05 41_[+1]_31 chr1:116901832-116901912 1.7e-05 27_[+1]_45 chr18:42304463-42304543 1.7e-05 56_[+1]_16 chr3:50288758-50288838 1.7e-05 17_[+1]_55 chr19:45657982-45658062 1.7e-05 42_[+1]_30 chrX:118926503-118926583 1.7e-05 9_[+1]_63 chr4:79572762-79572842 1.7e-05 14_[+1]_58 chr6:142433779-142433859 1.7e-05 32_[+1]_40 chr7:73258545-73258625 1.7e-05 2_[+1]_70 chr15:66080172-66080252 1.7e-05 13_[+1]_59 chr12:123002517-12300259 1.7e-05 38_[+1]_34 chr7:99845649-99845729 1.7e-05 12_[+1]_60 chr12:7394158-7394238 3.4e-05 56_[+1]_16 chr19:46265748-46265828 3.4e-05 [+1]_72 chr13:41255672-41255752 3.4e-05 63_[+1]_9 chr4:39559996-39560076 3.4e-05 17_[+1]_55 chr18:3639531-3639611 3.4e-05 16_[+1]_56 chr12:122634812-12263489 3.4e-05 21_[+1]_51 chr20:5718077-5718157 5.2e-05 6_[+1]_66 chr1:20848880-20848960 5.2e-05 58_[+1]_14 chr4:128454711-128454791 5.2e-05 37_[+1]_35 chr12:10902908-10902988 5.2e-05 49_[+1]_23 chr9:132806039-132806119 5.2e-05 8_[+1]_64 chr9:116160609-116160689 5.2e-05 26_[+1]_46 chr18:73552-73632 5.2e-05 23_[+1]_49 chr14:104305411-10430549 5.2e-05 17_[+1]_55 chr17:25615963-25616043 5.2e-05 26_[+1]_46 chr11:13132646-13132726 6.9e-05 41_[+1]_31 chr12:48214262-48214342 6.9e-05 30_[+1]_42 chr17:73402156-73402236 6.9e-05 56_[+1]_16 chr1:228272083-228272163 6.9e-05 23_[+1]_49 chr1:94371412-94371492 6.9e-05 39_[+1]_33 chr10:52153185-52153265 6.9e-05 5_[+1]_67 chr7:139975948-139976028 6.9e-05 60_[+1]_12 chr6:32054607-32054687 6.9e-05 55_[+1]_17 chr1:154077015-154077095 6.9e-05 26_[+1]_46 chr3:194295753-194295833 6.9e-05 37_[+1]_35 chr7:45030473-45030553 8.6e-05 40_[+1]_32 chr4:110660820-110660900 8.6e-05 [+1]_72 chr1:206287921-206288001 0.0001 10_[+1]_62 chr17:16176891-16176971 0.0001 6_[+1]_66 chr5:138524357-138524437 0.0001 9_[+1]_63 chr17:35425195-35425275 0.0001 44_[+1]_28 chr20:37089049-37089129 0.0001 43_[+1]_29 chr1:1353301-1353381 0.0001 24_[+1]_48 chr21:44369385-44369465 0.0001 16_[+1]_56 chr19:13162541-13162621 0.00012 54_[+1]_18 chr15:48847486-48847566 0.00012 68_[+1]_4 chr19:10974189-10974269 0.00012 72_[+1] chr12:1281025-1281105 0.00012 58_[+1]_14 chr12:117627569-11762764 0.00012 72_[+1] chr11:117720896-11772097 0.00012 58_[+1]_14 chr6:150173356-150173436 0.00014 38_[+1]_34 chr6:27204148-27204228 0.00014 70_[+1]_2 chr12:4430042-4430122 0.00014 39_[+1]_33 chr19:39794157-39794237 0.00014 21_[+1]_51 chr2:120916435-120916515 0.00014 44_[+1]_28 chr11:926619-926699 0.00014 3_[+1]_69 chr8:23204703-23204783 0.00015 45_[+1]_27 chr21:45277493-45277573 0.00015 28_[+1]_44 chr11:66846320-66846400 0.00015 54_[+1]_18 chr7:77344417-77344497 0.00015 50_[+1]_22 chr10:51576023-51576103 0.00019 39_[+1]_33 chr13:47695623-47695703 0.00019 14_[+1]_58 chr4:129181203-129181283 0.00019 50_[+1]_22 chrX:154083658-154083738 0.00019 42_[+1]_30 chr1:111019953-111020033 0.00019 16_[+1]_56 chr11:64995501-64995581 0.00019 49_[+1]_23 chr12:113817217-11381729 0.00024 40_[+1]_32 chr19:35865995-35866075 0.00024 5_[+1]_67 chr7:97847760-97847840 0.00024 72_[+1] chr17:26793839-26793919 0.00024 69_[+1]_3 chr6:105123218-105123298 0.00024 20_[+1]_52 chr2:97563445-97563525 0.00024 44_[+1]_28 chr6:90007837-90007917 0.00028 49_[+1]_23 chr12:516020-516100 0.00028 3_[+1]_69 chr1:9679088-9679168 0.00028 14_[+1]_58 chr1:41704238-41704318 0.00028 44_[+1]_28 chr2:152991156-152991236 0.00028 8_[+1]_64 chr4:164101370-164101450 0.00028 1_[+1]_71 chr2:192713667-192713747 0.00028 10_[+1]_62 chr16:30560846-30560926 0.00031 50_[+1]_22 chr19:50878394-50878474 0.00032 25_[+1]_47 chr6:36099635-36099715 0.00032 64_[+1]_8 chr9:141044417-141044497 0.00035 36_[+1]_36 chr12:133712490-13371257 0.0004 13_[+1]_59 chr6:33241784-33241864 0.0004 29_[+1]_43 chr9:36102390-36102470 0.00051 45_[+1]_27 chr7:30336136-30336216 0.00051 44_[+1]_28 chr9:114364073-114364153 0.00051 9_[+1]_63 chr1:28504836-28504916 0.00051 14_[+1]_58 chr10:120940549-12094062 0.00051 5_[+1]_67 chr3:196170804-196170884 0.00058 19_[+1]_53 chr7:151039260-151039340 0.00058 42_[+1]_30 chr1:211787468-211787548 0.00058 61_[+1]_11 chr5:173043106-173043186 0.00058 28_[+1]_44 chr1:6499488-6499568 0.00058 17_[+1]_55 chr7:124702161-124702241 0.00058 43_[+1]_29 chr12:24102311-24102391 0.00058 6_[+1]_66 chr17:42084540-42084620 0.00061 4_[+1]_68 chr15:72765340-72765420 0.00069 22_[+1]_50 chr7:45027718-45027798 0.00069 16_[+1]_56 chr3:58457174-58457254 0.00074 33_[+1]_39 chr18:12337043-12337123 0.00083 66_[+1]_6 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AATCWCWG MEME-1 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF AATCWCWG width=8 seqs=112 chr2:48731961-48732041 ( 51) AATCTCAG 1 chr12:93571613-93571693 ( 6) AATCTCAG 1 chr7:99160684-99160764 ( 54) AATCTCAG 1 chr12:96765330-96765410 ( 59) AATCTCAG 1 chr1:150228495-150228575 ( 16) AATCTCAG 1 chr7:102624231-102624311 ( 59) AATCTCAG 1 chr5:141742543-141742623 ( 53) AATCTCAG 1 chr18:323471-323551 ( 34) AATCTCAG 1 chr4:111080125-111080205 ( 42) AATCTCAG 1 chr1:116901832-116901912 ( 28) AATCTCAG 1 chr18:42304463-42304543 ( 57) AATCTCAG 1 chr3:50288758-50288838 ( 18) AATCTCAG 1 chr19:45657982-45658062 ( 43) AATCTCAG 1 chrX:118926503-118926583 ( 10) AATCTCAG 1 chr4:79572762-79572842 ( 15) AATCTCAG 1 chr6:142433779-142433859 ( 33) AATCTCAG 1 chr7:73258545-73258625 ( 3) AATCTCAG 1 chr15:66080172-66080252 ( 14) AATCTCAG 1 chr12:123002517-12300259 ( 39) AATCTCAG 1 chr7:99845649-99845729 ( 13) AATCTCAG 1 chr12:7394158-7394238 ( 57) AATCACAG 1 chr19:46265748-46265828 ( 1) AATCACAG 1 chr13:41255672-41255752 ( 64) AATCACAG 1 chr4:39559996-39560076 ( 18) AATCACAG 1 chr18:3639531-3639611 ( 17) AATCACAG 1 chr12:122634812-12263489 ( 22) AATCACAG 1 chr20:5718077-5718157 ( 7) AATCTCTG 1 chr1:20848880-20848960 ( 59) AATCTCTG 1 chr4:128454711-128454791 ( 38) AATCTCTG 1 chr12:10902908-10902988 ( 50) AATCTCTG 1 chr9:132806039-132806119 ( 9) AATCTCTG 1 chr9:116160609-116160689 ( 27) AATCTCTG 1 chr18:73552-73632 ( 24) AATCTCTG 1 chr14:104305411-10430549 ( 18) AATCTCTG 1 chr17:25615963-25616043 ( 27) AATCTCTG 1 chr11:13132646-13132726 ( 42) AATCACTG 1 chr12:48214262-48214342 ( 31) AATCACTG 1 chr17:73402156-73402236 ( 57) AATCACTG 1 chr1:228272083-228272163 ( 24) AATCACTG 1 chr1:94371412-94371492 ( 40) AATCACTG 1 chr10:52153185-52153265 ( 6) AATCACTG 1 chr7:139975948-139976028 ( 61) AATCACTG 1 chr6:32054607-32054687 ( 56) AATCACTG 1 chr1:154077015-154077095 ( 27) AATCACTG 1 chr3:194295753-194295833 ( 38) AATCACTG 1 chr7:45030473-45030553 ( 41) AATCTGAG 1 chr4:110660820-110660900 ( 1) AATCTGAG 1 chr1:206287921-206288001 ( 11) AATCAGAG 1 chr17:16176891-16176971 ( 7) AATCAGAG 1 chr5:138524357-138524437 ( 10) AATCAGAG 1 chr17:35425195-35425275 ( 45) AATCAGAG 1 chr20:37089049-37089129 ( 44) AATCAGAG 1 chr1:1353301-1353381 ( 25) AATCAGAG 1 chr21:44369385-44369465 ( 17) AATCAGAG 1 chr19:13162541-13162621 ( 55) AATCTGTG 1 chr15:48847486-48847566 ( 69) AATCTGTG 1 chr19:10974189-10974269 ( 73) AATCTGTG 1 chr12:1281025-1281105 ( 59) AATCTGTG 1 chr12:117627569-11762764 ( 73) AATCTGTG 1 chr11:117720896-11772097 ( 59) AATCTGTG 1 chr6:150173356-150173436 ( 39) AATCAGTG 1 chr6:27204148-27204228 ( 71) AATCAGTG 1 chr12:4430042-4430122 ( 40) AATCAGTG 1 chr19:39794157-39794237 ( 22) AATCAGTG 1 chr2:120916435-120916515 ( 45) AATCAGTG 1 chr11:926619-926699 ( 4) AATCAGTG 1 chr8:23204703-23204783 ( 46) AATCCCAG 1 chr21:45277493-45277573 ( 29) AATCCCAG 1 chr11:66846320-66846400 ( 55) AATCCCAG 1 chr7:77344417-77344497 ( 51) AATCCCAG 1 chr10:51576023-51576103 ( 40) AATCTCAT 1 chr13:47695623-47695703 ( 15) AATCCCTG 1 chr4:129181203-129181283 ( 51) AATCCCTG 1 chrX:154083658-154083738 ( 43) AATCTCAT 1 chr1:111019953-111020033 ( 17) AATCCCTG 1 chr11:64995501-64995581 ( 50) AATCTCAT 1 chr12:113817217-11381729 ( 41) AGTCTCAG 1 chr19:35865995-35866075 ( 6) AGTCTCAG 1 chr7:97847760-97847840 ( 73) AGTCTCAG 1 chr17:26793839-26793919 ( 70) AATCTCTT 1 chr6:105123218-105123298 ( 21) AGTCTCAG 1 chr2:97563445-97563525 ( 45) AATCTCTT 1 chr6:90007837-90007917 ( 50) AGTCACAG 1 chr12:516020-516100 ( 4) AATCACTT 1 chr1:9679088-9679168 ( 15) AATCACTT 1 chr1:41704238-41704318 ( 45) AATCACTT 1 chr2:152991156-152991236 ( 9) AATCACTT 1 chr4:164101370-164101450 ( 2) AATCACTT 1 chr2:192713667-192713747 ( 11) AATCACTT 1 chr16:30560846-30560926 ( 51) AGTCACTG 1 chr19:50878394-50878474 ( 26) AATCTCGG 1 chr6:36099635-36099715 ( 65) AATCTCGG 1 chr9:141044417-141044497 ( 37) AATCACGG 1 chr12:133712490-13371257 ( 14) AACCTCAG 1 chr6:33241784-33241864 ( 30) AACCTCAG 1 chr9:36102390-36102470 ( 46) AGTCTGAG 1 chr7:30336136-30336216 ( 45) AGTCTGAG 1 chr9:114364073-114364153 ( 10) AATCTGTT 1 chr1:28504836-28504916 ( 15) AACCTCTG 1 chr10:120940549-12094062 ( 6) AACCTCTG 1 chr3:196170804-196170884 ( 20) AATCAGTT 1 chr7:151039260-151039340 ( 43) AATCAAAG 1 chr1:211787468-211787548 ( 62) AATCAAAG 1 chr5:173043106-173043186 ( 29) AATCAAAG 1 chr1:6499488-6499568 ( 18) AATCAGTT 1 chr7:124702161-124702241 ( 44) AGTCAGAG 1 chr12:24102311-24102391 ( 7) AATCAGTT 1 chr17:42084540-42084620 ( 5) AATCTATG 1 chr15:72765340-72765420 ( 23) AATCAGGG 1 chr7:45027718-45027798 ( 17) AATCCCAT 1 chr3:58457174-58457254 ( 34) AACCTGAG 1 chr18:12337043-12337123 ( 67) AGTCACAT 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AATCWCWG MEME-1 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 9.01532 E= 4.2e-067 191 -1345 -1345 -1345 178 -1345 -135 -1345 -1345 -236 -1345 179 -1345 212 -1345 -1345 66 -168 -1345 88 -289 160 23 -1345 96 -1345 -267 69 -1345 -1345 190 -87 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AATCWCWG MEME-1 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 112 E= 4.2e-067 1.000000 0.000000 0.000000 0.000000 0.910714 0.000000 0.089286 0.000000 0.000000 0.044643 0.000000 0.955357 0.000000 1.000000 0.000000 0.000000 0.419643 0.071429 0.000000 0.508929 0.035714 0.696429 0.267857 0.000000 0.517857 0.000000 0.035714 0.446429 0.000000 0.000000 0.848214 0.151786 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AATCWCWG MEME-1 regular expression -------------------------------------------------------------------------------- AATC[TA][CG][AT]G -------------------------------------------------------------------------------- Time 4.97 secs. ******************************************************************************** ******************************************************************************** MOTIF CWSWGATT MEME-2 width = 8 sites = 119 llr = 881 E-value = 6.2e-065 ******************************************************************************** -------------------------------------------------------------------------------- Motif CWSWGATT MEME-2 Description -------------------------------------------------------------------------------- Simplified A 13:5:a:: pos.-specific C 724::::: probability G 1:6:a::: matrix T 25:5::aa bits 2.1 * 1.9 **** 1.7 **** 1.5 **** Relative 1.3 **** Entropy 1.1 **** (10.7 bits) 0.9 ****** 0.6 * ****** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel CTGTGATT consensus ACA sequence C -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CWSWGATT MEME-2 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr7:123178417-123178497 50 1.87e-05 CACATTCCCA CTGTGATT TCCTGTGAAT chr11:118444130-11844421 65 1.87e-05 TCCTTTATCG CTGTGATT TGTGGATA chr1:9679088-9679168 37 1.87e-05 taaatctgcg ctgtgatt gcctcatgac chr3:10187531-10187611 32 1.87e-05 GCAGGGTTTG CTGTGATT TGTAATCACG chr1:228352356-228352436 17 1.87e-05 TGATTTGAAG CTGTGATT GTGTCTCATC chr17:26793839-26793919 48 1.87e-05 CAGAGCACTG CTGTGATT TGTCAACAGC chr8:42158042-42158122 72 1.87e-05 GGCTGTGGGG CTGTGATT C chr1:148556813-148556893 41 1.87e-05 CAAAGAGTTG CTGTGATT TCCCTGTATC chr16:89231041-89231121 65 1.87e-05 ATGGTCGTTA CTGTGATT TATACGGC chr1:245498286-245498366 34 1.87e-05 TCCGCTGGGG CTGTGATT TCAGTTATCT chr12:109217674-10921775 36 1.87e-05 tcctggagtg ctgtgatt acaggcgtga chr7:124702161-124702241 65 1.87e-05 AGATTGATTT CTGTGATT CATTTGTC chr14:104305411-10430549 70 1.87e-05 tcccaagtag ctgtgatt aca chr1:40515082-40515162 67 3.65e-05 tccctaagtg ctgagatt acaggc chr16:30560846-30560926 34 3.65e-05 CAGCAAAGTg ctgagatt acaggcatga chr3:51573633-51573713 39 3.65e-05 TGATAGGCTA CTGAGATT GGAGAATCAG chr8:126935379-126935459 31 3.65e-05 tggAAATGGG CTGAGATT CAGAGAGGAC chrX:118606675-118606755 71 3.65e-05 TTACATAGTG CTGAGATT GC chrX:154083658-154083738 17 3.65e-05 agccacagag ctgagatt gctgaaaatc chr10:94404161-94404241 45 3.65e-05 tcccaagtag ctgagatt acaggcaccc chr6:30910553-30910633 34 3.65e-05 CACAGTCGCT CTGAGATT TGCTTCAGGG chr6:27562303-27562383 54 3.65e-05 ccaggcatgg ctgagatt gcgcatggct chr1:28504836-28504916 67 3.65e-05 tctggagtag ctgagatt acaggc chr20:37089049-37089129 64 3.65e-05 ccagtaacta ctgagatt gaatgagcc chr11:85960534-85960614 21 3.65e-05 GAATCCTCTT CTGAGATT AGAGAGCTGA chr6:33241784-33241864 50 3.65e-05 tcccaagtag ctgagatt acaggcacac chr7:73258545-73258625 51 3.65e-05 tgctgagtag ctgagatt acaggggaaa chr17:74249137-74249217 42 3.65e-05 tcccaaagtg ctgagatt acaggcgtga chr1:46379133-46379213 71 5.53e-05 CTTTCTGTAG CTCTGATT TG chr15:48847486-48847566 16 5.53e-05 GCTTCTAACG CTCTGATT CACCTCCGCA chr11:10428714-10428794 58 5.53e-05 TCCTGAAGGG CTCTGATT CATTCTTCTG chr8:30586967-30587047 54 5.53e-05 ttactggata ctctgatt ttggttttga chr5:149995643-149995723 32 5.53e-05 CCCTGGTTGG CTCTGATT TTCCCTGGGG chr7:100437717-100437797 15 5.53e-05 tttctagata ctctgatt ttagttttga chr5:86447525-86447605 25 5.53e-05 CCAACAGTAG CTCTGATT TACATTAAGT chr1:211861325-211861405 72 5.53e-05 tttctggaca ctctgatt t chr2:27201321-27201401 27 5.53e-05 TTACCTGGGA CTCTGATT TGGTCCTTGA chr1:167833313-167833393 54 5.53e-05 tttctgaata ctctgatt ttggttttga chr21:44353030-44353110 51 5.53e-05 tttctggata ctctgatt ttggttttga chr7:102793856-102793936 62 5.53e-05 tttctggata ctctgatt ttggttttga chr19:46265748-46265828 58 7.33e-05 acctctgcct ctcagatt ctcctgcctc chr21:18826682-18826762 16 9.12e-05 AGTGTGCGAA CAGTGATT TAAATCAGTC chr20:37499554-37499634 11 9.12e-05 GTAATTCCTG CAGTGATT CACACCCAGT chr9:132806039-132806119 21 9.12e-05 TCTCTGAAAC CAGTGATT TCCAACTTGT chr1:9034143-9034223 61 9.12e-05 TTCTATGTAG CAGTGATT GGCTGTGGTC chr1:231158439-231158519 31 9.12e-05 CATTGATCTG CAGTGATT TCTGCAAATC chr2:37465461-37465541 62 9.12e-05 gtgattgctg cagtgatt gattgcagag chr1:93914783-93914863 37 9.12e-05 GTGTGGAGGG CAGTGATT TCTCAGGTGC chr11:117720896-11772097 70 9.12e-05 atctgtgtca cagtgatt gat chr21:47012875-47012955 34 9.12e-05 acaaatctga cagtgatt taaagataac chr9:33151199-33151279 30 1.08e-04 TGAATTCAGC CAGAGATT TCTAAGCTAC chr9:97519492-97519572 4 1.08e-04 TTG CAGAGATT CAGAattatc chr1:65744880-65744960 31 1.08e-04 TGGTGGCGTG CAGAGATT GAACCCAGCT chr11:61876569-61876649 52 1.08e-04 acaGATTTTG CAGAGATT TATCCCTCAA chr9:141044417-141044497 72 1.08e-04 CGCTGATTTC CAGAGATT C chr6:150167638-150167718 46 1.08e-04 TGATTCGGAG CAGAGATT TAGAAGGTTG chr8:143808020-143808100 4 1.24e-04 CGG CCGTGATT TGCTCCGGTT chr22:20827622-20827702 47 1.24e-04 gctgggagtc ccgtgatt gtgtgatcag chr9:102864053-102864133 73 1.24e-04 cttgagttta ccgtgatt chr18:73552-73632 59 1.24e-04 TTTTTCCAGG CCGTGATT TTGGAAATTT chr12:516020-516100 40 1.57e-04 ttgcagtgag ccgagatt gcgccatcgc chr8:61705458-61705538 20 1.57e-04 AGCAGTTTTG CACTGATT TGATAAAAGA chr4:48700513-48700593 62 1.57e-04 GTGAGATTTA CACTGATT GACAGTTCCT chrX:118611819-118611899 16 1.57e-04 TATTTTACAA CACTGATT ATGAAAGAGA chr7:45030473-45030553 57 1.57e-04 agccactcca cactgatt tatttccctt chr17:46949153-46949233 21 1.57e-04 GAAGTTGCTG CACTGATT TGGCCTGTGC chr17:7530495-7530575 53 1.57e-04 CTCAGGGCTG CCGAGATT GGAGTTGTGA chr7:30280119-30280199 32 1.57e-04 CCACATTGTG CCGAGATT CATGGTTTGC chr1:1828723-1828803 17 1.57e-04 tcccaaagtg ccgagatt acaggcatga chr6:36099635-36099715 25 1.74e-04 cagcaaggct cacagatt agatggttag chr1:154077015-154077095 49 1.74e-04 cccccaggtg cacagatt tggagctcag chr11:926619-926699 60 1.89e-04 GCTTATTAAC CCCTGATT AGATCTCACC chr2:192713667-192713747 21 1.89e-04 AATCACTTCA CCCTGATT TTGCATTGAT chr2:161979964-161980044 45 2.04e-04 AGGAATCAAG CCCAGATT GTAAATCCAG chr10:120940549-12094062 17 2.04e-04 acctctgcct cccagatt caagcaatcc chr11:64995501-64995581 40 2.04e-04 gacctctaga cccagatt taaatctcat chr1:43325230-43325310 26 2.27e-04 cattccacta ttgtgatt tgttcctgcc chr16:2844641-2844721 63 2.48e-04 gattgttttt ttgagatt ttgtttggac chr4:128454711-128454791 6 2.89e-04 CAGCT TTCTGATT TGCTTAATGG chr5:173311825-173311905 15 2.89e-04 AGTTCACCTT GTGTGATT ATGGGGTGAG chr22:40895291-40895371 18 2.89e-04 GGATTCCTTG TTCTGATT CTCTGACTAA chr12:122634812-12263489 57 2.89e-04 GAATGGGGCA TTCTGATT GATCAGATTT chr15:72765340-72765420 67 3.29e-04 TGGCCAATTC TTCAGATT ATCTCA chr9:101089348-101089428 34 3.29e-04 TGCTTTCTCA TTCAGATT TTATGCCTGA chr1:111019953-111020033 49 3.29e-04 tctgtaaaat gtgagatt tACAAGCTCA chr3:196170804-196170884 40 4.11e-04 ccctagcact tagagatt tttaggataa chr1:29107974-29108054 65 4.68e-04 taggtcaggg gtcagatt aggtcagg chr7:102624231-102624311 33 4.68e-04 gggtcacagg atgagatt ctgcatttga chr13:47695623-47695703 61 4.68e-04 cataaactac atgagatt agctgggtgt chr17:38296201-38296281 46 4.68e-04 TTACCTTGAT TCGTGATT TTACCAAGCA chr1:159834208-159834288 17 4.68e-04 TGAggttgag gtcagatt tgaggttggg chr19:1018594-1018674 46 4.68e-04 AGGCAGCAGG GTCAGATT CTGTGCCACC chr10:52288116-52288196 23 5.25e-04 tgtcaaatgg tactgatt ttacatatga chr8:27192681-27192761 32 5.25e-04 CCTGGGAAGC TCGAGATT TGCAAACACT chr12:48214262-48214342 21 5.85e-04 AAGTTCCAGG ATCTGATT TGAATCACTG chr20:36155043-36155123 22 5.85e-04 AACAACATAT TACAGATT AAAGGTTAAA chr18:3639531-3639611 64 5.85e-04 TTGGCTTAAA ATCTGATT ACAGATGAG chr17:62530046-62530126 70 5.85e-04 CTGCCAAAGG GAGAGATT TAA chr11:96037278-96037358 60 5.85e-04 TATCACAGTG TACAGATT CTGAGGAGGG chr18:12337043-12337123 19 6.40e-04 TGAGGGAGAG TCCTGATT TGTTTACTTT chr18:19612513-19612593 40 6.40e-04 AGGCGGGTAG GCGTGATT TAGGTGTTTG chr9:36102390-36102470 33 7.33e-04 ATGTAAGCAG AAGTGATT CTATCAGTCT chr1:113216395-113216475 41 7.33e-04 ACAACACTAG CTTTGATT TATTTGAAAG chr6:150173356-150173436 2 7.33e-04 T TCCAGATT TGTTTTTGTT chr8:8871094-8871174 67 7.33e-04 ccgttccaaa tccagatt gcttat chr6:170166013-170166093 30 7.33e-04 AATCTCACTG AAGTGATT TCGTCACGCT chr4:110660820-110660900 35 7.33e-04 gagctgaaga tccagatt tgtgagtcac chr16:67523149-67523229 61 7.33e-04 gtgcctgtag ctttgatt tttcaaaaga chr10:1096180-1096260 31 7.33e-04 aaaaaacaga ctttgatt ttgttttatg chr11:66846320-66846400 22 7.33e-04 GATTAATAGG TCCAGATT gctgggcgtg chr1:116963178-116963258 8 7.92e-04 CTGGAGT GACAGATT AAACCAAACT chr1:205145175-205145255 46 7.92e-04 TGAATTCCTA AAGAGATT TCTCTTGTAG chr7:129595299-129595379 17 7.92e-04 ggccTGAACG AAGAGATT TCTATAACCT chr12:123002517-12300259 20 7.92e-04 TTCAGTGCCA GACAGATT AAGTGGTTAA chrX:117859006-117859086 64 8.25e-04 CAGGGCAGTG GCCTGATT CAATCCAAG chr12:117627569-11762764 45 8.78e-04 agtgtgcagg gccagatt tcatcctggg chr1:17035330-17035410 64 8.78e-04 ggttgaccat aactgatt ttgaccttt chr17:73402156-73402236 48 9.37e-04 TTTGTTTGCT CATTGATT GAATCACTGC chr7:97847760-97847840 46 1.01e-03 ccaaaagact cctagatt tgacatatga -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CWSWGATT MEME-2 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr7:123178417-123178497 1.9e-05 49_[+2]_23 chr11:118444130-11844421 1.9e-05 64_[+2]_8 chr1:9679088-9679168 1.9e-05 36_[+2]_36 chr3:10187531-10187611 1.9e-05 31_[+2]_41 chr1:228352356-228352436 1.9e-05 16_[+2]_56 chr17:26793839-26793919 1.9e-05 47_[+2]_25 chr8:42158042-42158122 1.9e-05 71_[+2]_1 chr1:148556813-148556893 1.9e-05 40_[+2]_32 chr16:89231041-89231121 1.9e-05 64_[+2]_8 chr1:245498286-245498366 1.9e-05 33_[+2]_39 chr12:109217674-10921775 1.9e-05 35_[+2]_37 chr7:124702161-124702241 1.9e-05 64_[+2]_8 chr14:104305411-10430549 1.9e-05 69_[+2]_3 chr1:40515082-40515162 3.6e-05 66_[+2]_6 chr16:30560846-30560926 3.6e-05 33_[+2]_39 chr3:51573633-51573713 3.6e-05 38_[+2]_34 chr8:126935379-126935459 3.6e-05 30_[+2]_42 chrX:118606675-118606755 3.6e-05 70_[+2]_2 chrX:154083658-154083738 3.6e-05 16_[+2]_56 chr10:94404161-94404241 3.6e-05 44_[+2]_28 chr6:30910553-30910633 3.6e-05 33_[+2]_39 chr6:27562303-27562383 3.6e-05 53_[+2]_19 chr1:28504836-28504916 3.6e-05 66_[+2]_6 chr20:37089049-37089129 3.6e-05 63_[+2]_9 chr11:85960534-85960614 3.6e-05 20_[+2]_52 chr6:33241784-33241864 3.6e-05 49_[+2]_23 chr7:73258545-73258625 3.6e-05 50_[+2]_22 chr17:74249137-74249217 3.6e-05 41_[+2]_31 chr1:46379133-46379213 5.5e-05 70_[+2]_2 chr15:48847486-48847566 5.5e-05 15_[+2]_57 chr11:10428714-10428794 5.5e-05 57_[+2]_15 chr8:30586967-30587047 5.5e-05 53_[+2]_19 chr5:149995643-149995723 5.5e-05 31_[+2]_41 chr7:100437717-100437797 5.5e-05 14_[+2]_58 chr5:86447525-86447605 5.5e-05 24_[+2]_48 chr1:211861325-211861405 5.5e-05 71_[+2]_1 chr2:27201321-27201401 5.5e-05 26_[+2]_46 chr1:167833313-167833393 5.5e-05 53_[+2]_19 chr21:44353030-44353110 5.5e-05 50_[+2]_22 chr7:102793856-102793936 5.5e-05 61_[+2]_11 chr19:46265748-46265828 7.3e-05 57_[+2]_15 chr21:18826682-18826762 9.1e-05 15_[+2]_57 chr20:37499554-37499634 9.1e-05 10_[+2]_62 chr9:132806039-132806119 9.1e-05 20_[+2]_52 chr1:9034143-9034223 9.1e-05 60_[+2]_12 chr1:231158439-231158519 9.1e-05 30_[+2]_42 chr2:37465461-37465541 9.1e-05 61_[+2]_11 chr1:93914783-93914863 9.1e-05 36_[+2]_36 chr11:117720896-11772097 9.1e-05 69_[+2]_3 chr21:47012875-47012955 9.1e-05 33_[+2]_39 chr9:33151199-33151279 0.00011 29_[+2]_43 chr9:97519492-97519572 0.00011 3_[+2]_69 chr1:65744880-65744960 0.00011 30_[+2]_42 chr11:61876569-61876649 0.00011 51_[+2]_21 chr9:141044417-141044497 0.00011 71_[+2]_1 chr6:150167638-150167718 0.00011 45_[+2]_27 chr8:143808020-143808100 0.00012 3_[+2]_69 chr22:20827622-20827702 0.00012 46_[+2]_26 chr9:102864053-102864133 0.00012 72_[+2] chr18:73552-73632 0.00012 58_[+2]_14 chr12:516020-516100 0.00016 39_[+2]_33 chr8:61705458-61705538 0.00016 19_[+2]_53 chr4:48700513-48700593 0.00016 61_[+2]_11 chrX:118611819-118611899 0.00016 15_[+2]_57 chr7:45030473-45030553 0.00016 56_[+2]_16 chr17:46949153-46949233 0.00016 20_[+2]_52 chr17:7530495-7530575 0.00016 52_[+2]_20 chr7:30280119-30280199 0.00016 31_[+2]_41 chr1:1828723-1828803 0.00016 16_[+2]_56 chr6:36099635-36099715 0.00017 24_[+2]_48 chr1:154077015-154077095 0.00017 48_[+2]_24 chr11:926619-926699 0.00019 59_[+2]_13 chr2:192713667-192713747 0.00019 20_[+2]_52 chr2:161979964-161980044 0.0002 44_[+2]_28 chr10:120940549-12094062 0.0002 16_[+2]_56 chr11:64995501-64995581 0.0002 39_[+2]_33 chr1:43325230-43325310 0.00023 25_[+2]_47 chr16:2844641-2844721 0.00025 62_[+2]_10 chr4:128454711-128454791 0.00029 5_[+2]_67 chr5:173311825-173311905 0.00029 14_[+2]_58 chr22:40895291-40895371 0.00029 17_[+2]_55 chr12:122634812-12263489 0.00029 56_[+2]_16 chr15:72765340-72765420 0.00033 66_[+2]_6 chr9:101089348-101089428 0.00033 33_[+2]_39 chr1:111019953-111020033 0.00033 48_[+2]_24 chr3:196170804-196170884 0.00041 39_[+2]_33 chr1:29107974-29108054 0.00047 64_[+2]_8 chr7:102624231-102624311 0.00047 32_[+2]_40 chr13:47695623-47695703 0.00047 60_[+2]_12 chr17:38296201-38296281 0.00047 45_[+2]_27 chr1:159834208-159834288 0.00047 16_[+2]_56 chr19:1018594-1018674 0.00047 45_[+2]_27 chr10:52288116-52288196 0.00053 22_[+2]_50 chr8:27192681-27192761 0.00053 31_[+2]_41 chr12:48214262-48214342 0.00058 20_[+2]_52 chr20:36155043-36155123 0.00058 21_[+2]_51 chr18:3639531-3639611 0.00058 63_[+2]_9 chr17:62530046-62530126 0.00058 69_[+2]_3 chr11:96037278-96037358 0.00058 59_[+2]_13 chr18:12337043-12337123 0.00064 18_[+2]_54 chr18:19612513-19612593 0.00064 39_[+2]_33 chr9:36102390-36102470 0.00073 32_[+2]_40 chr1:113216395-113216475 0.00073 40_[+2]_32 chr6:150173356-150173436 0.00073 1_[+2]_71 chr8:8871094-8871174 0.00073 66_[+2]_6 chr6:170166013-170166093 0.00073 29_[+2]_43 chr4:110660820-110660900 0.00073 34_[+2]_38 chr16:67523149-67523229 0.00073 60_[+2]_12 chr10:1096180-1096260 0.00073 30_[+2]_42 chr11:66846320-66846400 0.00073 21_[+2]_51 chr1:116963178-116963258 0.00079 7_[+2]_65 chr1:205145175-205145255 0.00079 45_[+2]_27 chr7:129595299-129595379 0.00079 16_[+2]_56 chr12:123002517-12300259 0.00079 19_[+2]_53 chrX:117859006-117859086 0.00083 63_[+2]_9 chr12:117627569-11762764 0.00088 44_[+2]_28 chr1:17035330-17035410 0.00088 63_[+2]_9 chr17:73402156-73402236 0.00094 47_[+2]_25 chr7:97847760-97847840 0.001 45_[+2]_27 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CWSWGATT MEME-2 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF CWSWGATT width=8 seqs=119 chr7:123178417-123178497 ( 50) CTGTGATT 1 chr11:118444130-11844421 ( 65) CTGTGATT 1 chr1:9679088-9679168 ( 37) CTGTGATT 1 chr3:10187531-10187611 ( 32) CTGTGATT 1 chr1:228352356-228352436 ( 17) CTGTGATT 1 chr17:26793839-26793919 ( 48) CTGTGATT 1 chr8:42158042-42158122 ( 72) CTGTGATT 1 chr1:148556813-148556893 ( 41) CTGTGATT 1 chr16:89231041-89231121 ( 65) CTGTGATT 1 chr1:245498286-245498366 ( 34) CTGTGATT 1 chr12:109217674-10921775 ( 36) CTGTGATT 1 chr7:124702161-124702241 ( 65) CTGTGATT 1 chr14:104305411-10430549 ( 70) CTGTGATT 1 chr1:40515082-40515162 ( 67) CTGAGATT 1 chr16:30560846-30560926 ( 34) CTGAGATT 1 chr3:51573633-51573713 ( 39) CTGAGATT 1 chr8:126935379-126935459 ( 31) CTGAGATT 1 chrX:118606675-118606755 ( 71) CTGAGATT 1 chrX:154083658-154083738 ( 17) CTGAGATT 1 chr10:94404161-94404241 ( 45) CTGAGATT 1 chr6:30910553-30910633 ( 34) CTGAGATT 1 chr6:27562303-27562383 ( 54) CTGAGATT 1 chr1:28504836-28504916 ( 67) CTGAGATT 1 chr20:37089049-37089129 ( 64) CTGAGATT 1 chr11:85960534-85960614 ( 21) CTGAGATT 1 chr6:33241784-33241864 ( 50) CTGAGATT 1 chr7:73258545-73258625 ( 51) CTGAGATT 1 chr17:74249137-74249217 ( 42) CTGAGATT 1 chr1:46379133-46379213 ( 71) CTCTGATT 1 chr15:48847486-48847566 ( 16) CTCTGATT 1 chr11:10428714-10428794 ( 58) CTCTGATT 1 chr8:30586967-30587047 ( 54) CTCTGATT 1 chr5:149995643-149995723 ( 32) CTCTGATT 1 chr7:100437717-100437797 ( 15) CTCTGATT 1 chr5:86447525-86447605 ( 25) CTCTGATT 1 chr1:211861325-211861405 ( 72) CTCTGATT 1 chr2:27201321-27201401 ( 27) CTCTGATT 1 chr1:167833313-167833393 ( 54) CTCTGATT 1 chr21:44353030-44353110 ( 51) CTCTGATT 1 chr7:102793856-102793936 ( 62) CTCTGATT 1 chr19:46265748-46265828 ( 58) CTCAGATT 1 chr21:18826682-18826762 ( 16) CAGTGATT 1 chr20:37499554-37499634 ( 11) CAGTGATT 1 chr9:132806039-132806119 ( 21) CAGTGATT 1 chr1:9034143-9034223 ( 61) CAGTGATT 1 chr1:231158439-231158519 ( 31) CAGTGATT 1 chr2:37465461-37465541 ( 62) CAGTGATT 1 chr1:93914783-93914863 ( 37) CAGTGATT 1 chr11:117720896-11772097 ( 70) CAGTGATT 1 chr21:47012875-47012955 ( 34) CAGTGATT 1 chr9:33151199-33151279 ( 30) CAGAGATT 1 chr9:97519492-97519572 ( 4) CAGAGATT 1 chr1:65744880-65744960 ( 31) CAGAGATT 1 chr11:61876569-61876649 ( 52) CAGAGATT 1 chr9:141044417-141044497 ( 72) CAGAGATT 1 chr6:150167638-150167718 ( 46) CAGAGATT 1 chr8:143808020-143808100 ( 4) CCGTGATT 1 chr22:20827622-20827702 ( 47) CCGTGATT 1 chr9:102864053-102864133 ( 73) CCGTGATT 1 chr18:73552-73632 ( 59) CCGTGATT 1 chr12:516020-516100 ( 40) CCGAGATT 1 chr8:61705458-61705538 ( 20) CACTGATT 1 chr4:48700513-48700593 ( 62) CACTGATT 1 chrX:118611819-118611899 ( 16) CACTGATT 1 chr7:45030473-45030553 ( 57) CACTGATT 1 chr17:46949153-46949233 ( 21) CACTGATT 1 chr17:7530495-7530575 ( 53) CCGAGATT 1 chr7:30280119-30280199 ( 32) CCGAGATT 1 chr1:1828723-1828803 ( 17) CCGAGATT 1 chr6:36099635-36099715 ( 25) CACAGATT 1 chr1:154077015-154077095 ( 49) CACAGATT 1 chr11:926619-926699 ( 60) CCCTGATT 1 chr2:192713667-192713747 ( 21) CCCTGATT 1 chr2:161979964-161980044 ( 45) CCCAGATT 1 chr10:120940549-12094062 ( 17) CCCAGATT 1 chr11:64995501-64995581 ( 40) CCCAGATT 1 chr1:43325230-43325310 ( 26) TTGTGATT 1 chr16:2844641-2844721 ( 63) TTGAGATT 1 chr4:128454711-128454791 ( 6) TTCTGATT 1 chr5:173311825-173311905 ( 15) GTGTGATT 1 chr22:40895291-40895371 ( 18) TTCTGATT 1 chr12:122634812-12263489 ( 57) TTCTGATT 1 chr15:72765340-72765420 ( 67) TTCAGATT 1 chr9:101089348-101089428 ( 34) TTCAGATT 1 chr1:111019953-111020033 ( 49) GTGAGATT 1 chr3:196170804-196170884 ( 40) TAGAGATT 1 chr1:29107974-29108054 ( 65) GTCAGATT 1 chr7:102624231-102624311 ( 33) ATGAGATT 1 chr13:47695623-47695703 ( 61) ATGAGATT 1 chr17:38296201-38296281 ( 46) TCGTGATT 1 chr1:159834208-159834288 ( 17) GTCAGATT 1 chr19:1018594-1018674 ( 46) GTCAGATT 1 chr10:52288116-52288196 ( 23) TACTGATT 1 chr8:27192681-27192761 ( 32) TCGAGATT 1 chr12:48214262-48214342 ( 21) ATCTGATT 1 chr20:36155043-36155123 ( 22) TACAGATT 1 chr18:3639531-3639611 ( 64) ATCTGATT 1 chr17:62530046-62530126 ( 70) GAGAGATT 1 chr11:96037278-96037358 ( 60) TACAGATT 1 chr18:12337043-12337123 ( 19) TCCTGATT 1 chr18:19612513-19612593 ( 40) GCGTGATT 1 chr9:36102390-36102470 ( 33) AAGTGATT 1 chr1:113216395-113216475 ( 41) CTTTGATT 1 chr6:150173356-150173436 ( 2) TCCAGATT 1 chr8:8871094-8871174 ( 67) TCCAGATT 1 chr6:170166013-170166093 ( 30) AAGTGATT 1 chr4:110660820-110660900 ( 35) TCCAGATT 1 chr16:67523149-67523229 ( 61) CTTTGATT 1 chr10:1096180-1096260 ( 31) CTTTGATT 1 chr11:66846320-66846400 ( 22) TCCAGATT 1 chr1:116963178-116963258 ( 8) GACAGATT 1 chr1:205145175-205145255 ( 46) AAGAGATT 1 chr7:129595299-129595379 ( 17) AAGAGATT 1 chr12:123002517-12300259 ( 20) GACAGATT 1 chrX:117859006-117859086 ( 64) GCCTGATT 1 chr12:117627569-11762764 ( 45) GCCAGATT 1 chr1:17035330-17035410 ( 64) AACTGATT 1 chr17:73402156-73402236 ( 48) CATTGATT 1 chr7:97847760-97847840 ( 46) CCTAGATT 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CWSWGATT MEME-2 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 8.95894 E= 6.2e-065 -181 157 -130 -87 15 -19 -1354 86 -1354 81 128 -272 80 -1354 -1354 96 -1354 -1354 213 -1354 191 -1354 -1354 -1354 -1354 -1354 -1354 185 -1354 -1354 -1354 185 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CWSWGATT MEME-2 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 119 E= 6.2e-065 0.075630 0.680672 0.092437 0.151261 0.294118 0.201681 0.000000 0.504202 0.000000 0.403361 0.554622 0.042017 0.462185 0.000000 0.000000 0.537815 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CWSWGATT MEME-2 regular expression -------------------------------------------------------------------------------- C[TAC][GC][TA]GATT -------------------------------------------------------------------------------- Time 8.58 secs. ******************************************************************************** ******************************************************************************** MOTIF VTGASTCA MEME-3 width = 8 sites = 47 llr = 397 E-value = 5.3e-016 ******************************************************************************** -------------------------------------------------------------------------------- Motif VTGASTCA MEME-3 Description -------------------------------------------------------------------------------- Simplified A 4::9:::a pos.-specific C 4::16:a: probability G 3:a:42:: matrix T :a:::8:: bits 2.1 * * 1.9 ** ** 1.7 ** ** 1.5 ** ** Relative 1.3 *** *** Entropy 1.1 ******* (12.2 bits) 0.9 ******* 0.6 ******* 0.4 ******** 0.2 ******** 0.0 -------- Multilevel ATGACTCA consensus C G sequence G -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif VTGASTCA MEME-3 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr12:7394158-7394238 31 1.49e-05 ATGAGACATC CTGACTCA GAGCTTGTTG chr9:116160609-116160689 7 1.49e-05 atctct ctgactcA CTTCCCACAA chr10:11799654-11799734 47 3.22e-05 ACTCAGAGCC ATGACTCA GGAACATGGC chr19:35865995-35866075 73 3.22e-05 gttgggtgcg atgactca chr1:41704238-41704318 67 3.22e-05 ctctacacag atgactca ttcaat chr17:43371031-43371111 51 3.22e-05 CCACATCACC ATGACTCA GACCCTCACC chr4:111080125-111080205 25 3.22e-05 ACAAATAGTC ATGACTCA CAAAATCTGA chr5:10487806-10487886 29 3.22e-05 GTTTGTTTGA ATGACTCA TTGTGCAGAT chr12:112621192-11262127 70 3.22e-05 CTTTTAGCAA ATGACTCA ACC chr1:111019953-111020033 5 3.22e-05 ctga atgactca gttcaatccc chr9:114364073-114364153 29 3.22e-05 CCCAAACTTG ATGACTCA GTCAGTCTCA chr1:1828723-1828803 31 3.22e-05 gattacaggc atgactca ccgtgcctgg chr2:48731961-48732041 36 6.18e-05 gccaggcatg gtgactca tgcctgtaat chr1:44509958-44510038 61 6.18e-05 TGTATTGGGG GTGACTCA GGGTTTGAGG chr9:75058384-75058464 67 6.18e-05 GCAGTTGGTT CTGAGTCA CTTGag chr22:32225558-32225638 54 6.18e-05 GCACTCAAGC GTGACTCA GTCTTTCTCC chr21:45277493-45277573 14 6.18e-05 gtcgggtgta gtgactca tgcctgtaat chr22:40895291-40895371 38 6.18e-05 CTGACTAATA CTGAGTCA TTTAAAGAAC chr11:66846320-66846400 40 6.18e-05 gctgggcgtg gtgactca cgcctgtaat chr12:123002517-12300259 56 6.18e-05 gctgggcaga gtgactca ctcctgaaat chr18:323471-323551 14 7.89e-05 tacatAACAG ATGAGTCA CAATGAGTTC chr9:97519492-97519572 56 7.89e-05 tcaactgaga atgagtca gcaagcttgg chr5:78054083-78054163 50 7.89e-05 TCTTGAATGC ATGAGTCA AACCTAAACT chr22:40002806-40002886 11 7.89e-05 gattacaggc atgagtca ctatgtctgg chr18:19612513-19612593 71 7.89e-05 AGTGACCATT ATGAGTCA GA chr7:99160684-99160764 4 9.36e-05 TCA GTGAGTCA CCCAGAATGG chr11:47536999-47537079 36 9.36e-05 GTCTTATCTA GTGAGTCA CTACTGCTCC chr3:58457174-58457254 72 9.36e-05 TGTGTGCAGA GTGAGTCA G chr4:110660820-110660900 44 9.36e-05 atccagattt gtgagtca ccggactgta chr19:45657982-45658062 28 9.36e-05 gccagtcgcg gtgagtca cgcctgtaat chr6:32054607-32054687 41 9.36e-05 TCTCACCACA GTGAGTCA GAACGGGAAT chr1:46379133-46379213 42 1.06e-04 GTGCTTGTCA CTGACGCA GGAACAAGGT chr17:38296201-38296281 9 1.06e-04 CAGCAAAT CTGACGCA GCACTACAGC chr19:46265748-46265828 69 1.57e-04 tcagattctc ctgcctca gcct chr8:23204703-23204783 66 1.57e-04 actcaggagg ctgaggca agagaat chrX:118611819-118611899 58 1.57e-04 TAAATCCGTC CTGCCTCA CAACCAGACT chr1:203648538-203648618 38 1.57e-04 CTAGATAAGC CTGAGGCA AACAAATCTT chr10:94404161-94404241 22 1.57e-04 accaattctc ctgcctca ctctctccca chr2:37465461-37465541 10 1.57e-04 ctcaggagg ctgaggca gggaatcgct chr1:28504836-28504916 46 1.57e-04 agggattctc ctgcctca gcctctggag chr10:120940549-12094062 37 1.57e-04 agcaatcctc ctgcctca gtctcccgag chr7:73258545-73258625 30 1.57e-04 cttccacttc ctgcctca gcctgctgag chr3:31586264-31586344 64 1.57e-04 attagacggg ctgaggca ggagaattg chr14:104305411-10430549 49 1.57e-04 agcgattctc ctgcctca gcctcccaag chr1:181687324-181687404 63 1.86e-04 CTTACTCAGC ATGAGGCA CTGAAATCAG chr1:245498286-245498366 62 1.86e-04 GTAAGAAAGC ATGAGGCA GCTAAAACCA chr1:228272083-228272163 57 2.24e-04 GCTGTTGCCT GTGAGGCA GATTTTCGGA -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif VTGASTCA MEME-3 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr12:7394158-7394238 1.5e-05 30_[+3]_42 chr9:116160609-116160689 1.5e-05 6_[+3]_66 chr10:11799654-11799734 3.2e-05 46_[+3]_26 chr19:35865995-35866075 3.2e-05 72_[+3] chr1:41704238-41704318 3.2e-05 66_[+3]_6 chr17:43371031-43371111 3.2e-05 50_[+3]_22 chr4:111080125-111080205 3.2e-05 24_[+3]_48 chr5:10487806-10487886 3.2e-05 28_[+3]_44 chr12:112621192-11262127 3.2e-05 69_[+3]_3 chr1:111019953-111020033 3.2e-05 4_[+3]_68 chr9:114364073-114364153 3.2e-05 28_[+3]_44 chr1:1828723-1828803 3.2e-05 30_[+3]_42 chr2:48731961-48732041 6.2e-05 35_[+3]_37 chr1:44509958-44510038 6.2e-05 60_[+3]_12 chr9:75058384-75058464 6.2e-05 66_[+3]_6 chr22:32225558-32225638 6.2e-05 53_[+3]_19 chr21:45277493-45277573 6.2e-05 13_[+3]_59 chr22:40895291-40895371 6.2e-05 37_[+3]_35 chr11:66846320-66846400 6.2e-05 39_[+3]_33 chr12:123002517-12300259 6.2e-05 55_[+3]_17 chr18:323471-323551 7.9e-05 13_[+3]_59 chr9:97519492-97519572 7.9e-05 55_[+3]_17 chr5:78054083-78054163 7.9e-05 49_[+3]_23 chr22:40002806-40002886 7.9e-05 10_[+3]_62 chr18:19612513-19612593 7.9e-05 70_[+3]_2 chr7:99160684-99160764 9.4e-05 3_[+3]_69 chr11:47536999-47537079 9.4e-05 35_[+3]_37 chr3:58457174-58457254 9.4e-05 71_[+3]_1 chr4:110660820-110660900 9.4e-05 43_[+3]_29 chr19:45657982-45658062 9.4e-05 27_[+3]_45 chr6:32054607-32054687 9.4e-05 40_[+3]_32 chr1:46379133-46379213 0.00011 41_[+3]_31 chr17:38296201-38296281 0.00011 8_[+3]_64 chr19:46265748-46265828 0.00016 68_[+3]_4 chr8:23204703-23204783 0.00016 65_[+3]_7 chrX:118611819-118611899 0.00016 57_[+3]_15 chr1:203648538-203648618 0.00016 37_[+3]_35 chr10:94404161-94404241 0.00016 21_[+3]_51 chr2:37465461-37465541 0.00016 9_[+3]_63 chr1:28504836-28504916 0.00016 45_[+3]_27 chr10:120940549-12094062 0.00016 36_[+3]_36 chr7:73258545-73258625 0.00016 29_[+3]_43 chr3:31586264-31586344 0.00016 63_[+3]_9 chr14:104305411-10430549 0.00016 48_[+3]_24 chr1:181687324-181687404 0.00019 62_[+3]_10 chr1:245498286-245498366 0.00019 61_[+3]_11 chr1:228272083-228272163 0.00022 56_[+3]_16 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif VTGASTCA MEME-3 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF VTGASTCA width=8 seqs=47 chr12:7394158-7394238 ( 31) CTGACTCA 1 chr9:116160609-116160689 ( 7) CTGACTCA 1 chr10:11799654-11799734 ( 47) ATGACTCA 1 chr19:35865995-35866075 ( 73) ATGACTCA 1 chr1:41704238-41704318 ( 67) ATGACTCA 1 chr17:43371031-43371111 ( 51) ATGACTCA 1 chr4:111080125-111080205 ( 25) ATGACTCA 1 chr5:10487806-10487886 ( 29) ATGACTCA 1 chr12:112621192-11262127 ( 70) ATGACTCA 1 chr1:111019953-111020033 ( 5) ATGACTCA 1 chr9:114364073-114364153 ( 29) ATGACTCA 1 chr1:1828723-1828803 ( 31) ATGACTCA 1 chr2:48731961-48732041 ( 36) GTGACTCA 1 chr1:44509958-44510038 ( 61) GTGACTCA 1 chr9:75058384-75058464 ( 67) CTGAGTCA 1 chr22:32225558-32225638 ( 54) GTGACTCA 1 chr21:45277493-45277573 ( 14) GTGACTCA 1 chr22:40895291-40895371 ( 38) CTGAGTCA 1 chr11:66846320-66846400 ( 40) GTGACTCA 1 chr12:123002517-12300259 ( 56) GTGACTCA 1 chr18:323471-323551 ( 14) ATGAGTCA 1 chr9:97519492-97519572 ( 56) ATGAGTCA 1 chr5:78054083-78054163 ( 50) ATGAGTCA 1 chr22:40002806-40002886 ( 11) ATGAGTCA 1 chr18:19612513-19612593 ( 71) ATGAGTCA 1 chr7:99160684-99160764 ( 4) GTGAGTCA 1 chr11:47536999-47537079 ( 36) GTGAGTCA 1 chr3:58457174-58457254 ( 72) GTGAGTCA 1 chr4:110660820-110660900 ( 44) GTGAGTCA 1 chr19:45657982-45658062 ( 28) GTGAGTCA 1 chr6:32054607-32054687 ( 41) GTGAGTCA 1 chr1:46379133-46379213 ( 42) CTGACGCA 1 chr17:38296201-38296281 ( 9) CTGACGCA 1 chr19:46265748-46265828 ( 69) CTGCCTCA 1 chr8:23204703-23204783 ( 66) CTGAGGCA 1 chrX:118611819-118611899 ( 58) CTGCCTCA 1 chr1:203648538-203648618 ( 38) CTGAGGCA 1 chr10:94404161-94404241 ( 22) CTGCCTCA 1 chr2:37465461-37465541 ( 10) CTGAGGCA 1 chr1:28504836-28504916 ( 46) CTGCCTCA 1 chr10:120940549-12094062 ( 37) CTGCCTCA 1 chr7:73258545-73258625 ( 30) CTGCCTCA 1 chr3:31586264-31586344 ( 64) CTGAGGCA 1 chr14:104305411-10430549 ( 49) CTGCCTCA 1 chr1:181687324-181687404 ( 63) ATGAGGCA 1 chr1:245498286-245498366 ( 62) ATGAGGCA 1 chr1:228272083-228272163 ( 57) GTGAGGCA 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif VTGASTCA MEME-3 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 9.68137 E= 5.3e-016 45 65 28 -1220 -1220 -1220 -1220 185 -1220 -1220 213 -1220 168 -62 -1220 -1220 -1220 132 90 -1220 -1220 -1220 -25 154 -1220 212 -1220 -1220 191 -1220 -1220 -1220 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif VTGASTCA MEME-3 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 47 E= 5.3e-016 0.361702 0.361702 0.276596 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.851064 0.148936 0.000000 0.000000 0.000000 0.574468 0.425532 0.000000 0.000000 0.000000 0.191489 0.808511 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif VTGASTCA MEME-3 regular expression -------------------------------------------------------------------------------- [ACG]TGA[CG]TCA -------------------------------------------------------------------------------- Time 11.99 secs. ******************************************************************************** ******************************************************************************** MOTIF CTTATCTS MEME-4 width = 8 sites = 17 llr = 163 E-value = 7.6e+000 ******************************************************************************** -------------------------------------------------------------------------------- Motif CTTATCTS MEME-4 Description -------------------------------------------------------------------------------- Simplified A :::a:::: pos.-specific C 7::::a:5 probability G 3::::::5 matrix T :aa:a:a: bits 2.1 * 1.9 ****** 1.7 ****** 1.5 ****** Relative 1.3 ******* Entropy 1.1 ******** (13.8 bits) 0.9 ******** 0.6 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel CTTATCTG consensus G C sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTTATCTS MEME-4 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr12:113817217-11381729 54 1.88e-05 ctcagattgc cttatctg caaagtgcag chr22:32225558-32225638 2 1.88e-05 C CTTATCTG TGACCCTACC chr2:152991156-152991236 48 1.88e-05 cctcagtgtc cttatctg taagacaggg chr8:42158042-42158122 14 1.88e-05 TCTTGCTGCT CTTATCTG TTCCCCAGTT chr1:111019953-111020033 35 1.88e-05 gttctatttc cttatctg taaaatgtga chr12:4430042-4430122 58 1.88e-05 CGCCGGCTTC CTTATCTG CCCCGAACGC chr4:108913520-108913600 39 1.88e-05 AGTGGTTTAG CTTATCTG CTTTTGCACC chr16:67523149-67523229 4 1.88e-05 tcc cttatctg tgcagctgca chr20:20391568-20391648 20 3.78e-05 GCCTCTCCCT CTTATCTC CCAACAAAGC chr5:149995643-149995723 62 3.78e-05 TGGTAATGCG CTTATCTC TCTGCCTGCC chr1:211854340-211854420 23 3.78e-05 GTGTATAAGT CTTATCTC CACAATTACT chr6:33241784-33241864 17 3.78e-05 atggtgcaat cttatctc actgcaacct chr1:245498286-245498366 45 5.65e-05 TGTGATTTCA GTTATCTG TAAGAAAGCA chr4:128454711-128454791 64 7.53e-05 CAGCTGAGTT GTTATCTC CCTGCACCT chr7:139975948-139976028 16 7.53e-05 TGGGATGGCT GTTATCTC CTCTAACTAC chr12:32260753-32260833 56 7.53e-05 CAAAACCGCT GTTATCTC AAACCCAGGT chr3:194295753-194295833 47 7.53e-05 aaatcactgC GTTATCTC ACGGTCATAT -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTTATCTS MEME-4 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr12:113817217-11381729 1.9e-05 53_[+4]_19 chr22:32225558-32225638 1.9e-05 1_[+4]_71 chr2:152991156-152991236 1.9e-05 47_[+4]_25 chr8:42158042-42158122 1.9e-05 13_[+4]_59 chr1:111019953-111020033 1.9e-05 34_[+4]_38 chr12:4430042-4430122 1.9e-05 57_[+4]_15 chr4:108913520-108913600 1.9e-05 38_[+4]_34 chr16:67523149-67523229 1.9e-05 3_[+4]_69 chr20:20391568-20391648 3.8e-05 19_[+4]_53 chr5:149995643-149995723 3.8e-05 61_[+4]_11 chr1:211854340-211854420 3.8e-05 22_[+4]_50 chr6:33241784-33241864 3.8e-05 16_[+4]_56 chr1:245498286-245498366 5.6e-05 44_[+4]_28 chr4:128454711-128454791 7.5e-05 63_[+4]_9 chr7:139975948-139976028 7.5e-05 15_[+4]_57 chr12:32260753-32260833 7.5e-05 55_[+4]_17 chr3:194295753-194295833 7.5e-05 46_[+4]_26 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTTATCTS MEME-4 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF CTTATCTS width=8 seqs=17 chr12:113817217-11381729 ( 54) CTTATCTG 1 chr22:32225558-32225638 ( 2) CTTATCTG 1 chr2:152991156-152991236 ( 48) CTTATCTG 1 chr8:42158042-42158122 ( 14) CTTATCTG 1 chr1:111019953-111020033 ( 35) CTTATCTG 1 chr12:4430042-4430122 ( 58) CTTATCTG 1 chr4:108913520-108913600 ( 39) CTTATCTG 1 chr16:67523149-67523229 ( 4) CTTATCTG 1 chr20:20391568-20391648 ( 20) CTTATCTC 1 chr5:149995643-149995723 ( 62) CTTATCTC 1 chr1:211854340-211854420 ( 23) CTTATCTC 1 chr6:33241784-33241864 ( 17) CTTATCTC 1 chr1:245498286-245498366 ( 45) GTTATCTG 1 chr4:128454711-128454791 ( 64) GTTATCTC 1 chr7:139975948-139976028 ( 16) GTTATCTC 1 chr12:32260753-32260833 ( 56) GTTATCTC 1 chr3:194295753-194295833 ( 47) GTTATCTC 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTTATCTS MEME-4 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 10.8621 E= 7.6e+000 -1073 162 37 -1073 -1073 -1073 -1073 185 -1073 -1073 -1073 185 191 -1073 -1073 -1073 -1073 -1073 -1073 185 -1073 212 -1073 -1073 -1073 -1073 -1073 185 -1073 103 122 -1073 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTTATCTS MEME-4 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 17 E= 7.6e+000 0.000000 0.705882 0.294118 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.470588 0.529412 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTTATCTS MEME-4 regular expression -------------------------------------------------------------------------------- [CG]TTATCT[GC] -------------------------------------------------------------------------------- Time 15.32 secs. ******************************************************************************** ******************************************************************************** MOTIF ARGYCAGG MEME-5 width = 8 sites = 27 llr = 233 E-value = 9.9e+000 ******************************************************************************** -------------------------------------------------------------------------------- Motif ARGYCAGG MEME-5 Description -------------------------------------------------------------------------------- Simplified A 66:1:a:: pos.-specific C 2::6a::: probability G 14a:::aa matrix T 2::3:::: bits 2.1 * * ** 1.9 * **** 1.7 * **** 1.5 * **** Relative 1.3 * **** Entropy 1.1 ** **** (12.4 bits) 0.9 ** **** 0.6 ******* 0.4 ******* 0.2 ******** 0.0 -------- Multilevel AAGCCAGG consensus G T sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ARGYCAGG MEME-5 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr8:22775933-22776013 54 1.17e-05 ATGTGCTGAT AAGCCAGG GCAACGAAAC chr2:54799552-54799632 57 1.17e-05 GCTTTGCTAG AAGCCAGG CAGTTAAATC chr1:206287921-206288001 32 1.17e-05 ccagaaatcc aagccagg tcaaaaccaa chr1:1353301-1353381 46 1.17e-05 ccagaaatcc aagccagg tcaaaaccaa chr21:44369385-44369465 38 1.17e-05 ccagaaatct aagccagg tcaaaaccaa chr3:50288758-50288838 62 2.17e-05 GGGCTGTACC AGGCCAGG GAAAAGCTTG chr1:211854340-211854420 53 3.58e-05 AAGCAATTTG AAGTCAGG GATTATGGCA chr2:48731961-48732041 24 4.59e-05 AATCTAGCAG CAgccagg catggtgact chr15:77838521-77838601 5 4.59e-05 AAGA CAGCCAGG ACGATGTGGG chr12:96765330-96765410 26 5.80e-05 ggatcacctg aggtcagg agttggaggc chr1:29107974-29108054 73 5.80e-05 gggtcagatt aggtcagg chr21:45277493-45277573 70 5.80e-05 agatcacctg aggtcagg agt chr4:164101370-164101450 35 5.80e-05 gcagcctaga aggtcagg ctgtaaaaca chr1:155367038-155367118 35 5.80e-05 ggatcacctg aggtcagg agttcaagac chr1:40515082-40515162 5 7.02e-05 attt tagccagg ctggtctcga chr6:27562303-27562383 41 7.02e-05 acaaaaaagt tagccagg catggctgag chr19:39794157-39794237 50 7.89e-05 tatgtgacct cggccagg ccgataagag chr6:135485649-135485729 14 8.94e-05 ttcaccatgt tggccagg ttggtcttga chr1:9034143-9034223 36 8.94e-05 ccatcgcgcc tggccAGG CCCAGATTTC chr1:196407719-196407799 38 1.02e-04 CTTGGAAAAG CAGTCAGG GAAAAAAGAT chr9:36102390-36102470 71 1.02e-04 CAACTGTGGT CAGTCAGG AA chr2:152991156-152991236 57 1.15e-04 ccttatctgt aagacagg gcaacaaaag chr11:10428714-10428794 1 1.15e-04 . AAGACAGG AACAGCCCAT chr1:116901832-116901912 6 1.40e-04 actct gagccagg ccataatccc chr7:77344417-77344497 24 1.40e-04 atacaaaaat tagtcagg tgtggtggca chr22:50971954-50972034 46 1.62e-04 ggaacagaac aggacagg gattttcaca chr17:35425195-35425275 25 1.83e-04 GTCTGGGCCT GGGCCAGG GCTGTGGCTT -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ARGYCAGG MEME-5 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr8:22775933-22776013 1.2e-05 53_[+5]_19 chr2:54799552-54799632 1.2e-05 56_[+5]_16 chr1:206287921-206288001 1.2e-05 31_[+5]_41 chr1:1353301-1353381 1.2e-05 45_[+5]_27 chr21:44369385-44369465 1.2e-05 37_[+5]_35 chr3:50288758-50288838 2.2e-05 61_[+5]_11 chr1:211854340-211854420 3.6e-05 52_[+5]_20 chr2:48731961-48732041 4.6e-05 23_[+5]_49 chr15:77838521-77838601 4.6e-05 4_[+5]_68 chr12:96765330-96765410 5.8e-05 25_[+5]_47 chr1:29107974-29108054 5.8e-05 72_[+5] chr21:45277493-45277573 5.8e-05 69_[+5]_3 chr4:164101370-164101450 5.8e-05 34_[+5]_38 chr1:155367038-155367118 5.8e-05 34_[+5]_38 chr1:40515082-40515162 7e-05 4_[+5]_68 chr6:27562303-27562383 7e-05 40_[+5]_32 chr19:39794157-39794237 7.9e-05 49_[+5]_23 chr6:135485649-135485729 8.9e-05 13_[+5]_59 chr1:9034143-9034223 8.9e-05 35_[+5]_37 chr1:196407719-196407799 0.0001 37_[+5]_35 chr9:36102390-36102470 0.0001 70_[+5]_2 chr2:152991156-152991236 0.00012 56_[+5]_16 chr11:10428714-10428794 0.00012 [+5]_72 chr1:116901832-116901912 0.00014 5_[+5]_67 chr7:77344417-77344497 0.00014 23_[+5]_49 chr22:50971954-50972034 0.00016 45_[+5]_27 chr17:35425195-35425275 0.00018 24_[+5]_48 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ARGYCAGG MEME-5 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF ARGYCAGG width=8 seqs=27 chr8:22775933-22776013 ( 54) AAGCCAGG 1 chr2:54799552-54799632 ( 57) AAGCCAGG 1 chr1:206287921-206288001 ( 32) AAGCCAGG 1 chr1:1353301-1353381 ( 46) AAGCCAGG 1 chr21:44369385-44369465 ( 38) AAGCCAGG 1 chr3:50288758-50288838 ( 62) AGGCCAGG 1 chr1:211854340-211854420 ( 53) AAGTCAGG 1 chr2:48731961-48732041 ( 24) CAGCCAGG 1 chr15:77838521-77838601 ( 5) CAGCCAGG 1 chr12:96765330-96765410 ( 26) AGGTCAGG 1 chr1:29107974-29108054 ( 73) AGGTCAGG 1 chr21:45277493-45277573 ( 70) AGGTCAGG 1 chr4:164101370-164101450 ( 35) AGGTCAGG 1 chr1:155367038-155367118 ( 35) AGGTCAGG 1 chr1:40515082-40515162 ( 5) TAGCCAGG 1 chr6:27562303-27562383 ( 41) TAGCCAGG 1 chr19:39794157-39794237 ( 50) CGGCCAGG 1 chr6:135485649-135485729 ( 14) TGGCCAGG 1 chr1:9034143-9034223 ( 36) TGGCCAGG 1 chr1:196407719-196407799 ( 38) CAGTCAGG 1 chr9:36102390-36102470 ( 71) CAGTCAGG 1 chr2:152991156-152991236 ( 57) AAGACAGG 1 chr11:10428714-10428794 ( 1) AAGACAGG 1 chr1:116901832-116901912 ( 6) GAGCCAGG 1 chr7:77344417-77344497 ( 24) TAGTCAGG 1 chr22:50971954-50972034 ( 46) AGGACAGG 1 chr17:35425195-35425275 ( 25) GGGCCAGG 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ARGYCAGG MEME-5 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 9.9683 E= 9.9e+000 107 -31 -162 -58 116 -1140 84 -1140 -1140 -1140 213 -1140 -125 127 -1140 27 -1140 212 -1140 -1140 191 -1140 -1140 -1140 -1140 -1140 213 -1140 -1140 -1140 213 -1140 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ARGYCAGG MEME-5 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 27 E= 9.9e+000 0.555556 0.185185 0.074074 0.185185 0.592593 0.000000 0.407407 0.000000 0.000000 0.000000 1.000000 0.000000 0.111111 0.555556 0.000000 0.333333 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ARGYCAGG MEME-5 regular expression -------------------------------------------------------------------------------- A[AG]G[CT]CAGG -------------------------------------------------------------------------------- Time 18.67 secs. ******************************************************************************** ******************************************************************************** SUMMARY OF MOTIFS ******************************************************************************** -------------------------------------------------------------------------------- Combined block diagrams: non-overlapping sites with p-value < 0.0001 -------------------------------------------------------------------------------- SEQUENCE NAME COMBINED P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr21:47012875-47012955 3.75e-02 33_[+2(9.12e-05)]_39 chr7:102793856-102793936 1.49e-01 61_[+2(5.53e-05)]_11 chr2:192713667-192713747 7.51e-02 80 chr21:44353030-44353110 1.49e-01 50_[+2(5.53e-05)]_22 chr21:44369385-44369465 3.18e-03 37_[+5(1.17e-05)]_35 chr3:194295753-194295833 2.70e-03 37_[+1(6.89e-05)]_1_[+4(7.53e-05)]_\ 26 chr11:64995501-64995581 1.11e-02 80 chr1:17035330-17035410 2.36e-01 80 chr17:25615963-25616043 2.26e-02 10_[+1(5.17e-05)]_8_[+1(5.17e-05)]_\ 46 chr14:104305411-10430549 8.82e-05 17_[+1(5.17e-05)]_44_[+2(1.87e-05)]_\ 3 chr11:926619-926699 2.46e-02 80 chr1:1353301-1353381 4.22e-03 45_[+5(1.17e-05)]_27 chr17:74249137-74249217 2.48e-02 41_[+2(3.65e-05)]_31 chr6:150167638-150167718 2.18e-01 80 chr18:19612513-19612593 1.59e-02 70_[+3(7.89e-05)]_2 chr7:77344417-77344497 4.18e-03 80 chr3:31586264-31586344 2.17e-02 80 chr18:73552-73632 8.45e-03 23_[+1(5.17e-05)]_49 chr7:99845649-99845729 2.20e-03 12_[+1(1.72e-05)]_60 chr17:42084540-42084620 6.05e-01 80 chr11:96037278-96037358 3.59e-03 80 chr12:122634812-12263489 2.08e-03 21_[+1(3.37e-05)]_51 chr12:32260753-32260833 6.54e-03 55_[+4(7.53e-05)]_17 chr16:14579255-14579335 3.72e-01 80 chr9:141044417-141044497 9.77e-03 80 chr11:117720896-11772097 6.14e-04 69_[+2(9.12e-05)]_3 chr12:123002517-12300259 1.24e-04 38_[+1(1.72e-05)]_9_[+3(6.18e-05)]_\ 17 chr19:17826814-17826894 2.67e-01 80 chr15:66080172-66080252 1.16e-03 13_[+1(1.72e-05)]_59 chr1:167833313-167833393 1.49e-01 53_[+2(5.53e-05)]_19 chr6:161827816-161827896 4.62e-01 80 chr7:73258545-73258625 4.36e-06 2_[+1(1.72e-05)]_40_[+2(3.65e-05)]_\ 22 chr10:120940549-12094062 4.78e-03 80 chr7:45027718-45027798 1.89e-01 80 chr1:154077015-154077095 1.89e-02 26_[+1(6.89e-05)]_46 chr8:27192681-27192761 4.21e-02 80 chr6:32054607-32054687 2.61e-03 40_[+3(9.36e-05)]_7_[+1(6.89e-05)]_\ 17 chr12:24102311-24102391 2.72e-01 80 chr2:121049641-121049721 6.86e-01 80 chr6:142433779-142433859 7.72e-02 32_[+1(1.72e-05)]_5_[+1(6.89e-05)]_\ 27 chr11:61876569-61876649 5.32e-02 80 chr6:33241784-33241864 3.95e-04 16_[+4(3.78e-05)]_25_[+2(3.65e-05)]_\ 23 chr13:114919164-11491924 9.46e-01 80 chr7:129595299-129595379 2.05e-01 80 chr7:124702161-124702241 6.02e-04 64_[+2(1.87e-05)]_8 chr12:109217674-10921775 1.05e-01 35_[+2(1.87e-05)]_37 chr11:85960534-85960614 6.84e-02 20_[+2(3.65e-05)]_6_[+2(3.65e-05)]_\ 38 chr9:116160609-116160689 2.06e-04 6_[+3(1.49e-05)]_12_[+1(5.17e-05)]_\ 46 chr11:66846320-66846400 2.94e-04 39_[+3(6.18e-05)]_33 chr4:79572762-79572842 9.76e-03 14_[+1(1.72e-05)]_58 chr20:37089049-37089129 2.92e-03 63_[+2(3.65e-05)]_9 chr10:1096180-1096260 2.56e-01 80 chr19:1018594-1018674 1.82e-01 80 chr7:139975948-139976028 5.03e-03 15_[+4(7.53e-05)]_37_[+1(6.89e-05)]_\ 12 chr1:93914783-93914863 1.51e-01 36_[+2(9.12e-05)]_16_[+2(9.12e-05)]_\ 12 chr1:28504836-28504916 8.28e-04 66_[+2(3.65e-05)]_6 chr3:196347293-196347373 6.54e-01 80 chr1:245498286-245498366 3.95e-05 33_[+2(1.87e-05)]_3_[+4(5.65e-05)]_\ 28 chr1:23886380-23886460 7.00e-01 80 chr1:159834208-159834288 1.90e-01 80 chr16:67523149-67523229 1.05e-02 3_[+4(1.88e-05)]_69 chr2:27201321-27201401 2.43e-02 26_[+2(5.53e-05)]_46 chr16:2844641-2844721 1.43e-01 80 chr17:35425195-35425275 2.39e-02 80 chr6:27562303-27562383 5.23e-04 40_[+5(7.02e-05)]_5_[+2(3.65e-05)]_\ 19 chr2:37465461-37465541 1.34e-03 49_[+2(9.12e-05)]_4_[+2(9.12e-05)]_\ 11 chr1:1828723-1828803 1.68e-03 30_[+3(3.22e-05)]_42 chrX:118926503-118926583 2.15e-03 9_[+1(1.72e-05)]_63 chr4:108913520-108913600 6.03e-02 38_[+4(1.88e-05)]_34 chr17:38296201-38296281 9.89e-03 80 chr1:155367038-155367118 7.19e-02 34_[+5(5.80e-05)]_38 chr2:191471946-191472026 4.86e-01 80 chr1:6499488-6499568 1.62e-01 80 chr12:117627569-11762764 3.21e-02 80 chr5:173043106-173043186 2.73e-01 80 chr16:89231041-89231121 6.56e-03 64_[+2(1.87e-05)]_8 chr9:114364073-114364153 2.13e-03 28_[+3(3.22e-05)]_44 chr1:211861325-211861405 1.68e-01 71_[+2(5.53e-05)]_1 chr22:40002806-40002886 1.80e-02 10_[+3(7.89e-05)]_62 chr2:120916435-120916515 3.60e-01 80 chr7:30280119-30280199 1.25e-01 80 chr12:31910162-31910242 4.26e-01 80 chr17:62530046-62530126 2.88e-01 80 chr1:231158439-231158519 3.46e-02 30_[+2(9.12e-05)]_42 chr1:211854340-211854420 2.01e-04 22_[+4(3.78e-05)]_22_[+5(3.58e-05)]_\ 20 chr6:30910553-30910633 8.88e-02 33_[+2(3.65e-05)]_25_[+2(3.65e-05)]_\ 6 chr10:52153185-52153265 5.33e-02 5_[+1(6.89e-05)]_67 chr1:9034143-9034223 3.03e-03 35_[+5(8.94e-05)]_17_[+2(9.12e-05)]_\ 12 chr22:29811052-29811132 2.46e-01 80 chr5:86447525-86447605 8.24e-02 24_[+2(5.53e-05)]_48 chr6:135485649-135485729 3.11e-02 13_[+5(8.94e-05)]_59 chr22:40895291-40895371 5.16e-03 37_[+3(6.18e-05)]_35 chr10:94404161-94404241 2.60e-03 44_[+2(3.65e-05)]_28 chrX:117859006-117859086 2.34e-03 80 chr19:39794157-39794237 8.78e-04 49_[+5(7.89e-05)]_23 chr12:4430042-4430122 1.73e-03 57_[+4(1.88e-05)]_15 chr6:27204148-27204228 1.96e-01 80 chr19:45657982-45658062 1.52e-04 27_[+3(9.36e-05)]_7_[+1(1.72e-05)]_\ 30 chr1:148556813-148556893 8.24e-02 40_[+2(1.87e-05)]_32 chr12:1281025-1281105 6.49e-02 80 chr7:100437717-100437797 1.80e-01 14_[+2(5.53e-05)]_58 chr9:132806039-132806119 1.59e-03 8_[+1(5.17e-05)]_4_[+2(9.12e-05)]_\ 52 chr3:50288758-50288838 3.70e-04 17_[+1(1.72e-05)]_36_[+5(2.17e-05)]_\ 11 chr19:10974189-10974269 1.23e-02 80 chr9:102864053-102864133 1.41e-01 80 chr1:94371412-94371492 2.30e-02 39_[+1(6.89e-05)]_33 chr1:111019953-111020033 7.02e-06 4_[+3(3.22e-05)]_22_[+4(1.88e-05)]_\ 38 chr1:61547423-61547503 4.18e-01 80 chr12:112621192-11262127 2.29e-02 69_[+3(3.22e-05)]_3 chr2:97563445-97563525 2.25e-02 80 chr8:42158042-42158122 9.62e-04 13_[+4(1.88e-05)]_50_[+2(1.87e-05)]_\ 1 chr1:159046749-159046829 4.19e-01 80 chr6:105123218-105123298 4.13e-01 80 chr2:111920529-111920609 5.02e-01 80 chr7:32818935-32819015 5.78e-01 80 chr5:10487806-10487886 7.30e-02 28_[+3(3.22e-05)]_44 chr1:109692017-109692097 3.35e-01 80 chr6:136572714-136572794 1.22e-01 80 chr1:181687324-181687404 1.77e-01 80 chr12:133712490-13371257 1.33e-02 80 chr4:110660820-110660900 4.06e-04 [+1(8.60e-05)]_35_[+3(9.36e-05)]_29 chr1:211787468-211787548 6.52e-02 80 chr5:138524357-138524437 8.84e-02 80 chr17:7530495-7530575 5.47e-02 80 chr18:42304463-42304543 1.61e-02 56_[+1(1.72e-05)]_16 chr2:161979964-161980044 2.26e-02 80 chr4:164101370-164101450 4.14e-03 34_[+5(5.80e-05)]_38 chrX:48510747-48510827 1.46e-01 80 chr1:23952622-23952702 1.00e+00 80 chr5:173311825-173311905 3.61e-01 80 chrX:154083658-154083738 1.49e-03 16_[+2(3.65e-05)]_56 chr1:228272083-228272163 9.04e-03 23_[+1(6.89e-05)]_49 chr6:36099635-36099715 4.55e-03 80 chr18:3639531-3639611 2.42e-02 16_[+1(3.37e-05)]_17_[+1(3.37e-05)]_\ 31 chr5:149995643-149995723 8.56e-03 31_[+2(5.53e-05)]_22_[+4(3.78e-05)]_\ 11 chr8:30586967-30587047 1.80e-01 53_[+2(5.53e-05)]_19 chr17:46949153-46949233 3.57e-02 80 chr17:26793839-26793919 1.72e-03 47_[+2(1.87e-05)]_25 chr22:20827622-20827702 4.73e-02 80 chr20:36155043-36155123 2.96e-01 80 chr1:203648538-203648618 1.64e-02 80 chr4:129181203-129181283 3.57e-02 80 chr4:39559996-39560076 2.38e-03 17_[+1(3.37e-05)]_55 chr11:10428714-10428794 5.49e-04 57_[+2(5.53e-05)]_15 chr6:170166013-170166093 2.58e-01 80 chr5:171711726-171711806 5.92e-02 80 chr1:116901832-116901912 2.33e-04 27_[+1(1.72e-05)]_45 chr21:45277493-45277573 1.95e-04 13_[+3(6.18e-05)]_48_[+5(5.80e-05)]_\ 3 chr7:30336136-30336216 4.38e-02 80 chr2:152991156-152991236 4.76e-05 47_[+4(1.88e-05)]_25 chr9:101089348-101089428 1.09e-01 80 chr13:47695623-47695703 1.00e-02 80 chr7:45030473-45030553 3.68e-04 40_[+1(8.60e-05)]_32 chr11:129830235-12983031 7.04e-01 80 chr12:10902908-10902988 1.19e-01 49_[+1(5.17e-05)]_23 chr3:58457174-58457254 2.17e-02 71_[+3(9.36e-05)]_1 chr19:50878394-50878474 5.51e-02 80 chr5:78054083-78054163 5.87e-02 49_[+3(7.89e-05)]_23 chr1:228352356-228352436 9.53e-03 16_[+2(1.87e-05)]_56 chr1:65744880-65744960 7.79e-02 80 chr3:10187531-10187611 1.41e-02 31_[+2(1.87e-05)]_41 chr7:151039260-151039340 2.14e-02 80 chr22:32225558-32225638 1.68e-03 1_[+4(1.88e-05)]_44_[+3(6.18e-05)]_\ 19 chr17:16176891-16176971 3.99e-02 80 chr2:240187008-240187088 3.93e-01 80 chr4:111080125-111080205 3.72e-04 24_[+3(3.22e-05)]_9_[+1(1.72e-05)]_\ 31 chr8:8871094-8871174 1.17e-01 80 chr3:196170804-196170884 1.09e-01 80 chr17:73402156-73402236 3.30e-02 56_[+1(6.89e-05)]_16 chr1:205145175-205145255 8.82e-02 80 chr9:97519492-97519572 1.63e-04 55_[+3(7.89e-05)]_17 chr16:21623470-21623550 3.60e-01 80 chr4:128454711-128454791 4.44e-04 37_[+1(5.17e-05)]_18_[+4(7.53e-05)]_\ 9 chr22:29666573-29666653 6.32e-01 80 chrX:118606675-118606755 4.29e-02 70_[+2(3.65e-05)]_2 chr12:48214262-48214342 1.75e-02 30_[+1(6.89e-05)]_42 chr6:150173356-150173436 5.11e-03 80 chr8:126935379-126935459 1.06e-02 30_[+2(3.65e-05)]_42 chr20:20391568-20391648 7.55e-03 19_[+4(3.78e-05)]_53 chr3:51573633-51573713 1.11e-02 38_[+2(3.65e-05)]_34 chr15:72765340-72765420 2.14e-03 80 chr11:44564062-44564142 9.96e-01 80 chr11:13132646-13132726 9.72e-03 41_[+1(6.89e-05)]_31 chr1:43325230-43325310 1.32e-02 80 chr5:159546947-159547027 3.03e-01 80 chr11:72297693-72297773 4.11e-01 80 chr18:323471-323551 1.66e-03 13_[+3(7.89e-05)]_12_[+1(1.72e-05)]_\ 8_[+1(1.72e-05)]_23 chr1:113216395-113216475 4.52e-01 80 chr13:41255672-41255752 1.17e-01 63_[+1(3.37e-05)]_9 chr10:52288116-52288196 1.46e-01 80 chr1:116963178-116963258 2.44e-01 80 chr17:43371031-43371111 2.99e-02 50_[+3(3.22e-05)]_22 chr5:141742543-141742623 1.42e-02 52_[+1(1.72e-05)]_20 chr9:75058384-75058464 8.87e-03 66_[+3(6.18e-05)]_6 chr1:206287921-206288001 2.77e-03 31_[+5(1.17e-05)]_41 chr1:20848880-20848960 2.12e-02 58_[+1(5.17e-05)]_14 chr7:97847760-97847840 3.50e-02 80 chr1:41704238-41704318 3.77e-03 66_[+3(3.22e-05)]_6 chr7:134278841-134278921 3.36e-01 80 chr2:54799552-54799632 4.79e-03 56_[+5(1.17e-05)]_16 chr7:102624231-102624311 1.87e-03 58_[+1(1.72e-05)]_14 chr20:37499554-37499634 2.24e-02 10_[+2(9.12e-05)]_31_[+2(9.12e-05)]_\ 23 chr8:22775933-22776013 3.18e-02 53_[+5(1.17e-05)]_19 chr1:29107974-29108054 1.51e-02 55_[+5(5.80e-05)]_9_[+5(5.80e-05)] chr1:150228495-150228575 8.36e-02 15_[+1(1.72e-05)]_57 chr15:48847486-48847566 1.18e-03 15_[+2(5.53e-05)]_57 chr1:44509958-44510038 9.14e-02 60_[+3(6.18e-05)]_12 chr19:34761001-34761081 6.15e-01 80 chrX:118611819-118611899 7.51e-03 80 chr8:17987766-17987846 4.37e-01 80 chr12:96765330-96765410 1.16e-03 25_[+5(5.80e-05)]_25_[+1(1.72e-05)]_\ 14 chr11:47536999-47537079 1.47e-03 35_[+3(9.36e-05)]_37 chr16:30560846-30560926 1.71e-04 33_[+2(3.65e-05)]_6_[+3(7.89e-05)]_\ 25 chr1:9679088-9679168 4.41e-03 36_[+2(1.87e-05)]_36 chr1:46379133-46379213 5.26e-03 70_[+2(5.53e-05)]_2 chr11:118444130-11844421 6.37e-03 64_[+2(1.87e-05)]_8 chr10:97501762-97501842 6.23e-01 80 chr8:23204703-23204783 1.06e-02 80 chr9:36102390-36102470 2.85e-03 80 chr1:196407719-196407799 8.63e-02 80 chr8:143808020-143808100 5.77e-02 80 chr4:48700513-48700593 3.28e-01 80 chr7:99160684-99160764 2.71e-04 3_[+3(9.36e-05)]_42_[+1(1.72e-05)]_\ 19 chr21:18826682-18826762 3.34e-02 15_[+2(9.12e-05)]_57 chr9:33151199-33151279 5.17e-03 80 chr19:35865995-35866075 4.99e-03 72_[+3(3.22e-05)] chr15:77838521-77838601 6.46e-03 4_[+5(4.59e-05)]_68 chr7:30510018-30510098 4.93e-01 80 chr12:93571613-93571693 2.05e-03 5_[+1(1.72e-05)]_67 chr8:61705458-61705538 1.07e-01 80 chr7:123178417-123178497 5.77e-03 49_[+2(1.87e-05)]_23 chr19:54605751-54605831 6.14e-01 80 chr19:46265748-46265828 4.19e-04 [+1(3.37e-05)]_29_[+1(6.89e-05)]_12_\ [+2(7.33e-05)]_15 chr20:5718077-5718157 6.31e-03 6_[+1(5.17e-05)]_66 chr12:516020-516100 5.27e-03 80 chr10:11799654-11799734 4.00e-02 46_[+3(3.22e-05)]_26 chr2:48731961-48732041 1.30e-05 23_[+5(4.59e-05)]_4_[+3(6.18e-05)]_\ 7_[+1(1.72e-05)]_22 chr1:114911364-114911444 1.38e-01 80 chr12:7394158-7394238 9.48e-04 30_[+3(1.49e-05)]_18_[+1(3.37e-05)]_\ 16 chr10:121186926-12118700 9.61e-01 80 chr12:42838649-42838729 1.92e-01 80 chr19:13162541-13162621 5.24e-03 80 chr1:40515082-40515162 2.85e-04 4_[+5(7.02e-05)]_54_[+2(3.65e-05)]_\ 6 chr22:50971954-50972034 5.91e-02 80 chr10:51576023-51576103 2.56e-01 80 chr6:90007837-90007917 1.70e-03 46_[+3(7.89e-05)]_26 chr1:247500632-247500712 3.58e-01 80 chr5:66502917-66502997 3.03e-01 80 chr18:12337043-12337123 3.75e-02 80 chr12:113817217-11381729 6.10e-05 43_[+2(7.33e-05)]_2_[+4(1.88e-05)]_\ 19 -------------------------------------------------------------------------------- ******************************************************************************** ******************************************************************************** Stopped because requested number of motifs (5) found. ******************************************************************************** CPU: c22n04.farnam.hpc.yale.internal ********************************************************************************