******************************************************************************** MEME - Motif discovery tool ******************************************************************************** MEME version 5.3.3 (Release date: Sun Feb 7 15:39:52 2021 -0800) For further information on how to interpret these results please access https://meme-suite.org/meme. To get a copy of the MEME Suite software please access https://meme-suite.org. ******************************************************************************** ******************************************************************************** REFERENCE ******************************************************************************** If you use this program in your research, please cite: Timothy L. Bailey and Charles Elkan, "Fitting a mixture model by expectation maximization to discover motifs in biopolymers", Proceedings of the Second International Conference on Intelligent Systems for Molecular Biology, pp. 28-36, AAAI Press, Menlo Park, California, 1994. ******************************************************************************** ******************************************************************************** TRAINING SET ******************************************************************************** PRIMARY SEQUENCES= ../result/final_prediction/K562/fasta/RankLinear0.6_40/HNRNPL.fasta CONTROL SEQUENCES= --none-- ALPHABET= ACGT Sequence name Weight Length Sequence name Weight Length ------------- ------ ------ ------------- ------ ------ chr4:1239386-1239466 1.0000 80 chr19:1326038-1326118 1.0000 80 chr8:145024678-145024758 1.0000 80 chr19:588419-588499 1.0000 80 chr20:32255245-32255325 1.0000 80 chr17:17875297-17875377 1.0000 80 chr12:133304152-13330423 1.0000 80 chr3:15373345-15373425 1.0000 80 chr19:3388004-3388084 1.0000 80 chr10:134996472-13499655 1.0000 80 chr1:113261503-113261583 1.0000 80 chr20:62447372-62447452 1.0000 80 chr20:61922719-61922799 1.0000 80 chr16:88520804-88520884 1.0000 80 chr21:45354840-45354920 1.0000 80 chr16:88941503-88941583 1.0000 80 chr19:815473-815553 1.0000 80 chr6:169250261-169250341 1.0000 80 chr9:139493024-139493104 1.0000 80 chr20:60889081-60889161 1.0000 80 chr22:19746260-19746340 1.0000 80 chr10:134794148-13479422 1.0000 80 chr16:88503933-88504013 1.0000 80 chr16:22012442-22012522 1.0000 80 chr5:1227127-1227207 1.0000 80 chr20:61675384-61675464 1.0000 80 chr11:66624076-66624156 1.0000 80 chr10:71168694-71168774 1.0000 80 chr9:139001633-139001713 1.0000 80 chr21:46553871-46553951 1.0000 80 chr22:20136080-20136160 1.0000 80 chr3:32148268-32148348 1.0000 80 chrX:153029586-153029666 1.0000 80 chr13:41363579-41363659 1.0000 80 chr22:20785623-20785703 1.0000 80 chr11:63438342-63438422 1.0000 80 chr17:76127758-76127838 1.0000 80 chr11:62380913-62380993 1.0000 80 chr16:84964523-84964603 1.0000 80 chr6:137113099-137113179 1.0000 80 chr8:145910361-145910441 1.0000 80 chr7:150774067-150774147 1.0000 80 chr19:1003404-1003484 1.0000 80 chr1:2025972-2026052 1.0000 80 chr1:27854659-27854739 1.0000 80 chr22:29704276-29704356 1.0000 80 chr19:1004830-1004910 1.0000 80 chr7:76029726-76029806 1.0000 80 chr7:2491189-2491269 1.0000 80 chr8:142397009-142397089 1.0000 80 chr12:53441411-53441491 1.0000 80 chr17:80194438-80194518 1.0000 80 chr9:139539028-139539108 1.0000 80 chr1:1268534-1268614 1.0000 80 chr12:132619265-13261934 1.0000 80 chr19:36247707-36247787 1.0000 80 chr19:17393512-17393592 1.0000 80 chr22:50247123-50247203 1.0000 80 chr8:141521748-141521828 1.0000 80 chr7:150652765-150652845 1.0000 80 chrX:49042878-49042958 1.0000 80 chr2:153572551-153572631 1.0000 80 chr7:100463734-100463814 1.0000 80 chr2:208634536-208634616 1.0000 80 chr19:13113512-13113592 1.0000 80 chr1:33815039-33815119 1.0000 80 chr12:105629681-10562976 1.0000 80 chr9:139907670-139907750 1.0000 80 chr17:38226734-38226814 1.0000 80 chr3:128207425-128207505 1.0000 80 chr20:36793710-36793790 1.0000 80 chr19:13260800-13260880 1.0000 80 chr3:122786165-122786245 1.0000 80 chr10:13342069-13342149 1.0000 80 chr15:40650472-40650552 1.0000 80 chr1:3639464-3639544 1.0000 80 chr19:1482248-1482328 1.0000 80 chr1:28835426-28835506 1.0000 80 chr10:127511554-12751163 1.0000 80 chr15:40574801-40574881 1.0000 80 chr3:167813530-167813610 1.0000 80 chr17:74497340-74497420 1.0000 80 chr7:150068534-150068614 1.0000 80 chr17:80036466-80036546 1.0000 80 chr22:20134524-20134604 1.0000 80 chr1:1823075-1823155 1.0000 80 chr9:137230861-137230941 1.0000 80 chr22:20785405-20785485 1.0000 80 chr7:36192732-36192812 1.0000 80 chr17:44896299-44896379 1.0000 80 chr21:46554070-46554150 1.0000 80 chr10:71078244-71078324 1.0000 80 chr8:120886251-120886331 1.0000 80 chr20:31215029-31215109 1.0000 80 chr11:119039579-11903965 1.0000 80 chr19:982870-982950 1.0000 80 chr20:47896562-47896642 1.0000 80 chr4:1007167-1007247 1.0000 80 chr9:95857808-95857888 1.0000 80 chr8:144489707-144489787 1.0000 80 chr19:46289225-46289305 1.0000 80 chr17:52978037-52978117 1.0000 80 chr7:73704753-73704833 1.0000 80 chr17:76111750-76111830 1.0000 80 chr5:115177868-115177948 1.0000 80 chr10:135074953-13507503 1.0000 80 chr17:79409130-79409210 1.0000 80 chr3:150481007-150481087 1.0000 80 chr2:191045055-191045135 1.0000 80 chr16:2867178-2867258 1.0000 80 chr10:121302330-12130241 1.0000 80 chr7:23510795-23510875 1.0000 80 chr20:36013153-36013233 1.0000 80 chr2:242707707-242707787 1.0000 80 chrX:38663246-38663326 1.0000 80 chr12:1771153-1771233 1.0000 80 chrX:153191838-153191918 1.0000 80 chr17:79894744-79894824 1.0000 80 chr16:89255027-89255107 1.0000 80 chr19:18546485-18546565 1.0000 80 chr6:109415978-109416058 1.0000 80 chr19:18547820-18547900 1.0000 80 chr4:1750619-1750699 1.0000 80 chr10:126298991-12629907 1.0000 80 chr11:65269791-65269871 1.0000 80 chr3:152879940-152880020 1.0000 80 chr16:88948911-88948991 1.0000 80 chr14:105191441-10519152 1.0000 80 chr19:39898573-39898653 1.0000 80 chr17:76310351-76310431 1.0000 80 chr15:58358600-58358680 1.0000 80 chr2:10091265-10091345 1.0000 80 chr14:104314558-10431463 1.0000 80 chr1:28286595-28286675 1.0000 80 chr13:60970536-60970616 1.0000 80 chr9:139128806-139128886 1.0000 80 chr16:23847888-23847968 1.0000 80 chr17:35716324-35716404 1.0000 80 chr20:30200751-30200831 1.0000 80 chr19:813402-813482 1.0000 80 chr5:171615753-171615833 1.0000 80 chr13:41885604-41885684 1.0000 80 chr19:940864-940944 1.0000 80 chr11:94277409-94277489 1.0000 80 chr3:195603617-195603697 1.0000 80 chr16:710555-710635 1.0000 80 chr7:150706593-150706673 1.0000 80 chr13:103425966-10342604 1.0000 80 chr12:132335922-13233600 1.0000 80 chr19:10224712-10224792 1.0000 80 chr7:157293807-157293887 1.0000 80 chr20:60932393-60932473 1.0000 80 chr16:67563064-67563144 1.0000 80 chr16:699300-699380 1.0000 80 chr1:117113065-117113145 1.0000 80 chr19:17622906-17622986 1.0000 80 chr6:139694951-139695031 1.0000 80 chr5:153569895-153569975 1.0000 80 chr11:64126769-64126849 1.0000 80 chr6:158177829-158177909 1.0000 80 chr1:32228458-32228538 1.0000 80 chr7:5633461-5633541 1.0000 80 chr19:1021147-1021227 1.0000 80 chr10:52383653-52383733 1.0000 80 chr16:726668-726748 1.0000 80 chr19:41833680-41833760 1.0000 80 chr5:137802151-137802231 1.0000 80 chr20:5986627-5986707 1.0000 80 chr19:41173098-41173178 1.0000 80 chr1:1057656-1057736 1.0000 80 chr16:85286874-85286954 1.0000 80 chr2:220041686-220041766 1.0000 80 chr17:76111955-76112035 1.0000 80 chr9:94712536-94712616 1.0000 80 chr19:42784540-42784620 1.0000 80 chr16:89118860-89118940 1.0000 80 chr17:79700958-79701038 1.0000 80 chrX:48958370-48958450 1.0000 80 chr17:7199739-7199819 1.0000 80 chr10:80063107-80063187 1.0000 80 chr4:1389220-1389300 1.0000 80 chr5:96271725-96271805 1.0000 80 chr11:61347876-61347956 1.0000 80 chr11:67071012-67071092 1.0000 80 chr9:34637704-34637784 1.0000 80 chr1:16342604-16342684 1.0000 80 chr21:44313138-44313218 1.0000 80 chr7:129465461-129465541 1.0000 80 chr19:47743011-47743091 1.0000 80 chr1:153919185-153919265 1.0000 80 chr19:952906-952986 1.0000 80 chr10:74034646-74034726 1.0000 80 chr19:39522676-39522756 1.0000 80 chr19:1466053-1466133 1.0000 80 chr3:48936272-48936352 1.0000 80 chr16:31153824-31153904 1.0000 80 chr3:48885154-48885234 1.0000 80 chr9:131102104-131102184 1.0000 80 chr16:1243494-1243574 1.0000 80 chr22:19511394-19511474 1.0000 80 chr7:158496782-158496862 1.0000 80 chr16:3019934-3020014 1.0000 80 chr1:228559093-228559173 1.0000 80 chr19:14584495-14584575 1.0000 80 chr5:2038837-2038917 1.0000 80 chr9:131872926-131873006 1.0000 80 chr20:60889281-60889361 1.0000 80 chr19:15491000-15491080 1.0000 80 chr19:17799114-17799194 1.0000 80 chr8:124169172-124169252 1.0000 80 chr1:115053226-115053306 1.0000 80 chr1:54204430-54204510 1.0000 80 chr1:23854884-23854964 1.0000 80 chr1:51434731-51434811 1.0000 80 chr14:96858278-96858358 1.0000 80 chr13:53024743-53024823 1.0000 80 chr2:227656318-227656398 1.0000 80 chr1:226310146-226310226 1.0000 80 chr9:131057713-131057793 1.0000 80 chr17:76124728-76124808 1.0000 80 chr9:35749126-35749206 1.0000 80 chr1:36787934-36788014 1.0000 80 chr19:50373302-50373382 1.0000 80 chr4:95373395-95373475 1.0000 80 chr11:64808772-64808852 1.0000 80 chr16:778573-778653 1.0000 80 chr5:150414226-150414306 1.0000 80 chr3:20081509-20081589 1.0000 80 chr19:17416316-17416396 1.0000 80 chr7:72848523-72848603 1.0000 80 chr16:21313040-21313120 1.0000 80 chr6:30569986-30570066 1.0000 80 chr14:23771378-23771458 1.0000 80 chr4:57843233-57843313 1.0000 80 chr5:141704185-141704265 1.0000 80 chr8:23082319-23082399 1.0000 80 chr2:176944745-176944825 1.0000 80 chr20:62328228-62328308 1.0000 80 chr9:34652164-34652244 1.0000 80 chr9:126031146-126031226 1.0000 80 chr9:124132117-124132197 1.0000 80 chr5:6633681-6633761 1.0000 80 chr2:136289413-136289493 1.0000 80 chr1:61519611-61519691 1.0000 80 chr5:149110312-149110392 1.0000 80 chr5:179248432-179248512 1.0000 80 chr1:6266531-6266611 1.0000 80 chr4:185394217-185394297 1.0000 80 chr1:54871071-54871151 1.0000 80 chr10:61666257-61666337 1.0000 80 ******************************************************************************** ******************************************************************************** COMMAND LINE SUMMARY ******************************************************************************** This information can also be useful in the event you wish to report a problem with the MEME software. command: meme -oc ../result/final_prediction/K562/inference_raw/MEME/RankLinear0.6_40_HNRNPL/ -dna -nmotifs 5 -w 8 -maxsize 250000 -nostatus ../result/final_prediction/K562/fasta/RankLinear0.6_40/HNRNPL.fasta model: mod= zoops nmotifs= 5 evt= inf objective function: em= E-value of product of p-values starts= E-value of product of p-values strands: + width: minw= 8 maxw= 8 nsites: minsites= 2 maxsites= 250 wnsites= 0.8 theta: spmap= uni spfuzz= 0.5 em: prior= dirichlet b= 0.01 maxiter= 50 distance= 1e-05 trim: wg= 11 ws= 1 endgaps= yes data: n= 20000 N= 250 sample: seed= 0 hsfrac= 0 searchsize= 20000 norand= no csites= 1000 Letter frequencies in dataset: A 0.136 C 0.36 G 0.374 T 0.131 Background letter frequencies (from file dataset with add-one prior applied): A 0.136 C 0.36 G 0.374 T 0.131 Background model order: 0 ******************************************************************************** ******************************************************************************** MOTIF YGGGCASN MEME-1 width = 8 sites = 134 llr = 846 E-value = 1.6e-020 ******************************************************************************** -------------------------------------------------------------------------------- Motif YGGGCASN MEME-1 Description -------------------------------------------------------------------------------- Simplified A 1::::a12 pos.-specific C 6:::a:53 probability G :7aa::33 matrix T 33::::12 bits 2.9 * 2.6 * 2.3 * 2.1 * Relative 1.8 * Entropy 1.5 **** (9.1 bits) 1.2 **** 0.9 ****** 0.6 ****** 0.3 ****** 0.0 -------- Multilevel CGGGCACC consensus TT GG sequence T A -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YGGGCASN MEME-1 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr19:952906-952986 51 2.91e-05 CCTGTGACCT TGGGCACT GCTGGGGGAG chr1:1057656-1057736 33 2.91e-05 GGCCCGGACC TGGGCACT GCACTTGGCG chr8:141521748-141521828 60 2.91e-05 CGCCGGGCTC TGGGCACT GCCCAGTCCC chr20:61675384-61675464 57 2.91e-05 CAGGGGAACG TGGGCACT GTGGACCGGG chr16:778573-778653 65 4.77e-05 TCTTCTCCCG TGGGCACA GCCCCCAC chr17:76111955-76112035 49 4.77e-05 GCGAAGGGAG TGGGCACA GGGACCAGCT chr17:76111750-76111830 65 4.77e-05 gcgaagggag tgggcaca ggggcgaa chr7:100463734-100463814 28 4.77e-05 TGGTGCCCGC TTGGCATA GCGCCCGGCT chr11:62380913-62380993 61 4.77e-05 GCGGTGGCTC TGGGCACA GGACTAGTGG chr20:60889081-60889161 69 4.77e-05 GGGTGGCGAG TGGGCACA GACG chr20:62447372-62447452 64 4.77e-05 tgggcacagg tgggcaca ggtgcagtg chr10:134996472-13499655 23 4.77e-05 ACAGGCGGCG TGGGCACA GGCGGCAAGG chr7:129465461-129465541 39 6.86e-05 GTGGCCGTGG CTGGCACT GCGGCAGTGC chr22:20785623-20785703 59 6.86e-05 ACGTGCCGTG CTGGCACT GGCACGCATG chr1:113261503-113261583 19 6.86e-05 AGCCGAGCGC CTGGCACT GTCCCGAAGG chr19:588419-588499 44 6.86e-05 GGGCCACAGC CTGGCACT GCCAACTGTG chr5:150414226-150414306 42 9.04e-05 GGCTGGAACA TGGGCATA GAAAGTTGGA chr10:127511554-12751163 71 9.04e-05 AGCACCCGGC CTGGCACA CA chr1:3639464-3639544 60 9.04e-05 ctctctgtgc ctggcaca gggctgggca chr19:815473-815553 68 9.04e-05 TGCCCACAGG CTGGCACA GGCCC chr5:179248432-179248512 63 1.60e-04 TGGCTCTCCG CGGGCACT GGGTGGTCAG chr8:23082319-23082399 56 1.60e-04 TGCCCGGGCC CGGGCACT GGGTCCGTGC chr4:57843233-57843313 50 1.60e-04 GGCAGGTAGC CGGGCACT CCGGCGTCCT chr16:726668-726748 55 1.60e-04 TAACGGACAG CGGGCACT GCCCCGGGAC chr17:79409130-79409210 22 1.60e-04 TGCCAGCCGA CGGGCACT GCAGGGAGGG chr22:20134524-20134604 28 1.60e-04 AGGGGGCGGA TTGGCACC TGCACCCGTG chr3:122786165-122786245 29 1.60e-04 GCCAGGCAGG CGGGCACT GGGTGCTACG chr19:13113512-13113592 24 1.60e-04 AGGCGGGTAG CGGGCACT GCGGCGCTCT chr10:71168694-71168774 12 1.60e-04 GTGGCGCAGG TTGGCACC GTGCGCCTGA chr16:22012442-22012522 14 1.60e-04 ACCTTGCCCG CGGGCACT GCCCTCGGGA chr2:176944745-176944825 41 2.33e-04 AGGGGACTCC CGGGCACA CTCAGAGAGG chr17:74497340-74497420 16 2.33e-04 AGGGCAGGCT CGGGCACA ACCTCGGGAC chr1:28835426-28835506 34 2.33e-04 TTGACAATCT TTGGCAGA CTTGGAGCAA chr12:133304152-13330423 63 2.33e-04 CCTGGCACCG CGGGCACA CGCGCCCGGG chr8:145024678-145024758 73 2.33e-04 TTGGTGACGC CGGGCACA chr19:1326038-1326118 61 2.33e-04 TCACACCAGC CGGGCACA GTGGCTCAAA chr9:124132117-124132197 27 3.20e-04 GGCATGGGGC TTGGCATC TGGCGGCCGC chr11:64808772-64808852 15 3.20e-04 GAGCTGCCCG TGGGCACC TGCCCGGACA chr17:35716324-35716404 61 3.20e-04 gggcgggccc TGGGCAGT CGTGGCGCCC chr1:28286595-28286675 65 3.20e-04 CTGCTCGACC TGGGCACC GACCTGTG chr7:23510795-23510875 30 3.20e-04 TCTCGGGCCC TGGGCACC GCGCGAGTGG chr3:32148268-32148348 71 3.20e-04 TGCTGCGGCG TGGGCACC GG chr9:131057713-131057793 64 4.13e-04 GGTGTCATAG TGGGCACG GCCTCGAGG chrX:48958370-48958450 29 4.13e-04 CAGGACGGGA TGGGCACG AGCATGCCGG chr9:94712536-94712616 20 4.13e-04 CCCGCCCCGA TGGGCAGA GCGAGGCTTg chr17:38226734-38226814 50 4.13e-04 GGTGCCCGTG TTGGCATG GGGGGCAGTG chr6:169250261-169250341 54 4.13e-04 ACGGGCCTTG TGGGCAGA GGTGGCACGG chr10:61666257-61666337 39 5.07e-04 AGCTGAGCGC CTGGCACC AGGGCGCAGA chr16:3019934-3020014 22 5.07e-04 TGCCCCGGCC CTGGCACC GCCAGTAGCC chr3:48885154-48885234 61 5.07e-04 cacggccgac ctggcacc gccgccgctg chr1:16342604-16342684 7 5.07e-04 GCACAT TGGGCATC TGCCCGCCAG chr11:61347876-61347956 9 5.07e-04 CGCCAGCG CTGGCACC CCCGGGGCAC chr16:89118860-89118940 53 5.07e-04 CCGGCCCTCC CTGGCACC TCTGCCAACT chr19:42784540-42784620 25 5.07e-04 CCAGCCCCCG CTGGCACC TAGGGGTGTG chr6:158177829-158177909 47 5.07e-04 GAGAGGAAAC TGGGCATC TCAGCAACAA chr12:132335922-13233600 13 5.07e-04 ACGGGCCACC CTGGCACC GGAAGGCCAG chr16:710555-710635 55 5.07e-04 CCTTCCTCGC AGGGCACT TGCCCGCCTC chr5:171615753-171615833 24 5.07e-04 CCGGCAGGCG AGGGCACT CGCCCCAGGC chr14:105191441-10519152 20 5.07e-04 GACCCCGTGG CTGGCAGT GCCACCGAGG chr10:135074953-13507503 58 5.07e-04 GCGCGCCAGC CTGGCACC ACGGGGACGC chr19:982870-982950 47 5.07e-04 GCCGCACGCT CTGGCACC AGCCTCCTGC chr22:20785405-20785485 19 5.07e-04 CGCGGAAGCA CTGGCAGT AGCGATCGCA chr15:40574801-40574881 13 5.07e-04 cccgggcAGC CTGGCAGT TCCGCACGGG chr7:150652765-150652845 9 5.07e-04 GGGTCACC CTGGCAGT AAGCGTGGGC chr7:2491189-2491269 9 5.07e-04 CCGGGCCC TGGGCATC TTCCACCAGG chr19:1004830-1004910 13 5.07e-04 TGCCTGGACC CTGGCACC AACGACTCGG chr20:32255245-32255325 38 5.07e-04 GTTCGAGACC CTGGCAGT GCCCGCGTGC chr3:20081509-20081589 47 6.08e-04 CCTCCCAGCG CTGGCAGA CACCGTGAGG chr14:96858278-96858358 4 6.08e-04 cgc ctggcacg ccctgattag chr1:54204430-54204510 20 6.08e-04 ACCGGCACAG TGGGCAAT GCCCACGCGG chr21:44313138-44313218 58 6.08e-04 AGGCGCCCGC AGGGCACA GGGATCGGCA chr9:34637704-34637784 4 6.08e-04 GGC CTGGCACG GCGCAGCTCA chr5:96271725-96271805 48 6.08e-04 GAGGCCGCGC TGGGCATG CTCAGTCAGC chr16:88948911-88948991 58 6.08e-04 tggctgtgtg tgggcatg gctgtgggcg chr3:152879940-152880020 13 6.08e-04 CGGAACGCAC TGGGCATG CTCGCCGGGG chr6:109415978-109416058 20 6.08e-04 GCCGAGCCAG AGGGCACA GGGCGGCCCT chr3:150481007-150481087 11 6.08e-04 CGCGCGGGGA CTGGCAGA GCCACCCTGC chr10:71078244-71078324 28 6.08e-04 ACCTCCCCGC CTGGCACG GCCCACCCGG chr1:33815039-33815119 28 6.08e-04 AGAGCCGCGA CTGGCACG GCCTGGCAGC chr1:1268534-1268614 59 6.08e-04 CAGTCTCCCG TGGGCATG CCCAGCCGAG chr16:84964523-84964603 44 6.08e-04 taagtgggtg tgggcatg ggtgtggatg chr11:66624076-66624156 58 6.08e-04 TGTGGGTGTG TGGGCATG TGTGGGTGTG chr9:139493024-139493104 40 6.08e-04 CAGGGCAGTG TGGGCATG AGGGCAGCAG chr7:157293807-157293887 72 8.16e-04 CGGGGCATGA CGGGCACC T chr13:41885604-41885684 13 8.16e-04 GCGGAGCGCC CGGGCACC TAGCCTCCCT chr12:1771153-1771233 42 8.16e-04 TGCCAGCGGA CGGGCACC TCCGCGGGCG chr8:144489707-144489787 13 8.16e-04 GGGGCAGCCC CGGGCACC GACGGTGGCA chr7:76029726-76029806 33 8.16e-04 GGCCGTGGCA CGGGCAGT GCCAGGCCAC chr22:29704276-29704356 45 8.16e-04 TGCCCGTGCA TTGGCAGC CGCCCGCCCG chrX:153029586-153029666 13 8.16e-04 CCTGTGCCAT TGGGCAAA GGGGCGGGCG chr16:88520804-88520884 51 8.16e-04 CGGATGCCCG CGGGCACC CCCTGGCATC chr20:30200751-30200831 33 1.03e-03 CGCCCCCTCC CGGGCAGA GCCCGGGCTA chr1:1823075-1823155 14 1.03e-03 ACGCGGCTGA CGGGCAGA GACTCGCGCT chr19:13260800-13260880 71 1.03e-03 CCCAGCCCGC CGGGCACG CT chr11:63438342-63438422 8 1.03e-03 GAGTGCC CGGGCACG GAGGGGCAGC chr13:41363579-41363659 17 1.03e-03 GGTCTCGGCT CGGGCACG GCCCTGGGCA chr9:139001633-139001713 46 1.03e-03 CCGGCATGCC CGGGCACG CTGCCCAGCT chr1:23854884-23854964 56 1.15e-03 GGCTGGGCCC CGGGCATC TGGGGATTGA chr8:145910361-145910441 14 1.15e-03 ACCCGACCGG CGGGCATC CACCTTGTCC chr1:226310146-226310226 3 1.28e-03 AG CGGGCAAT TCGCTGCGGC chr6:139694951-139695031 54 1.28e-03 GCCCATGCGG TGGGCAGG GTGATGGTGC chr2:242707707-242707787 65 1.28e-03 GCTCGTTCCC CGGGCATG CGTGGGCA chr11:119039579-11903965 53 1.28e-03 CGGGCGGAGG TGGGCAGG AAGCGCCACG chr15:40650472-40650552 46 1.28e-03 GTGCCGCCCA CGGGCATG GACGGTGAca chrX:49042878-49042958 17 1.28e-03 ggcccgcccc cgggcATG TGGTCTCTCC chr7:158496782-158496862 41 1.42e-03 ACGCTCTCTG AGGGCAGT GCCCATGCCC chr20:60932393-60932473 36 1.42e-03 CTGCTCGGAC AGGGCACC GGGGCACCCA chr9:139539028-139539108 20 1.42e-03 CCGCCCAAGG CTGGCAGC AGCAGGGTAG chr12:53441411-53441491 59 1.42e-03 CCGGCAGCAG CTGGCAGC GGCGCTCGGG chr9:34652164-34652244 32 1.55e-03 ggcgagggcg agggcaga gggcgctggc chr14:23771378-23771458 12 1.55e-03 GGGCGCGGGG CTGGCAGG GCGCGAAGTG chr19:15491000-15491080 22 1.55e-03 CCTCCCAGCA AGGGCACG GCGCCCTCCT chr16:31153824-31153904 40 1.71e-03 GGCGGGTCTC CGGGCAGC GGTACTGCCG chr17:7199739-7199819 42 1.71e-03 CAGGCGCTGC TGGGCAAG CCCCACGTGC chr19:813402-813482 52 1.71e-03 CTGGCGTCGT CGGGCAGC CCCAGGCCGC chr19:36247707-36247787 13 1.71e-03 ACCTGGGCGA CGGGCAGC GCCACGCTGG chr1:27854659-27854739 29 1.71e-03 CAGCGCTAGG CGGGCAGC CCCGGGCGCA chr19:50373302-50373382 52 1.88e-03 CAGCGCCGGC AGGGCAAT CCCCCTGCAC chr1:115053226-115053306 6 1.88e-03 CGGCT CGGGCAGG CAGCGCAGGC chr10:80063107-80063187 63 1.88e-03 gggcgcgggg cgggcAGG ATCGATGCCC chr1:32228458-32228538 8 1.88e-03 GGCGAGG CGGGCAGG CAGGCGGCAT chr9:95857808-95857888 10 1.88e-03 GCAGGGCTC CGGGCAGG AGCGGGCGCC chr7:150774067-150774147 71 1.88e-03 GACGTGGCTC AGGGCATG GC chr4:1239386-1239466 46 1.88e-03 gtggcatgga cgggcagg gtgacacggg chr19:18546485-18546565 46 1.98e-03 CACCCCTCGC CGGGCAAc cccgcgcccg chr20:60889281-60889361 26 2.08e-03 AGATGGCGAA CGGGCAAG GGCCCTGCAG chr19:1021147-1021227 16 2.08e-03 GTCGCCACGC CGGGCAAG AGCGGCCCCC chr1:117113065-117113145 19 2.08e-03 CCGCGCGGGG AGGGCAGC AGGCGTCGCC chr7:150706593-150706673 69 2.08e-03 CAGCTGGAGA AGGGCAGC CCTG chr2:191045055-191045135 52 2.08e-03 GAGGCCTTGG AGGGCAGC GCCCCCTCTC chr5:6633681-6633761 9 2.13e-03 CCCTGGCG ATGGCAAC GGCGACGGGG chr8:124169172-124169252 70 2.13e-03 ggcaagggcg agggcaGG TCG chr22:20136080-20136160 62 2.13e-03 CTGGCCTAGA AGGGCAGG AAGCCGTCCA chr10:74034646-74034726 59 2.17e-03 TGCGTGGAGC AGGGCAAG AGCTGCCACA -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YGGGCASN MEME-1 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr19:952906-952986 2.9e-05 50_[+1]_22 chr1:1057656-1057736 2.9e-05 32_[+1]_40 chr8:141521748-141521828 2.9e-05 59_[+1]_13 chr20:61675384-61675464 2.9e-05 56_[+1]_16 chr16:778573-778653 4.8e-05 64_[+1]_8 chr17:76111955-76112035 4.8e-05 48_[+1]_24 chr17:76111750-76111830 4.8e-05 64_[+1]_8 chr7:100463734-100463814 4.8e-05 27_[+1]_45 chr11:62380913-62380993 4.8e-05 60_[+1]_12 chr20:60889081-60889161 4.8e-05 68_[+1]_4 chr20:62447372-62447452 4.8e-05 63_[+1]_9 chr10:134996472-13499655 4.8e-05 22_[+1]_50 chr7:129465461-129465541 6.9e-05 38_[+1]_34 chr22:20785623-20785703 6.9e-05 58_[+1]_14 chr1:113261503-113261583 6.9e-05 18_[+1]_54 chr19:588419-588499 6.9e-05 43_[+1]_29 chr5:150414226-150414306 9e-05 41_[+1]_31 chr10:127511554-12751163 9e-05 70_[+1]_2 chr1:3639464-3639544 9e-05 59_[+1]_13 chr19:815473-815553 9e-05 67_[+1]_5 chr5:179248432-179248512 0.00016 62_[+1]_10 chr8:23082319-23082399 0.00016 55_[+1]_17 chr4:57843233-57843313 0.00016 49_[+1]_23 chr16:726668-726748 0.00016 54_[+1]_18 chr17:79409130-79409210 0.00016 21_[+1]_51 chr22:20134524-20134604 0.00016 27_[+1]_45 chr3:122786165-122786245 0.00016 28_[+1]_44 chr19:13113512-13113592 0.00016 23_[+1]_49 chr10:71168694-71168774 0.00016 11_[+1]_61 chr16:22012442-22012522 0.00016 13_[+1]_59 chr2:176944745-176944825 0.00023 40_[+1]_32 chr17:74497340-74497420 0.00023 15_[+1]_57 chr1:28835426-28835506 0.00023 33_[+1]_39 chr12:133304152-13330423 0.00023 62_[+1]_10 chr8:145024678-145024758 0.00023 72_[+1] chr19:1326038-1326118 0.00023 60_[+1]_12 chr9:124132117-124132197 0.00032 26_[+1]_46 chr11:64808772-64808852 0.00032 14_[+1]_58 chr17:35716324-35716404 0.00032 60_[+1]_12 chr1:28286595-28286675 0.00032 64_[+1]_8 chr7:23510795-23510875 0.00032 29_[+1]_43 chr3:32148268-32148348 0.00032 70_[+1]_2 chr9:131057713-131057793 0.00041 63_[+1]_9 chrX:48958370-48958450 0.00041 28_[+1]_44 chr9:94712536-94712616 0.00041 19_[+1]_53 chr17:38226734-38226814 0.00041 49_[+1]_23 chr6:169250261-169250341 0.00041 53_[+1]_19 chr10:61666257-61666337 0.00051 38_[+1]_34 chr16:3019934-3020014 0.00051 21_[+1]_51 chr3:48885154-48885234 0.00051 60_[+1]_12 chr1:16342604-16342684 0.00051 6_[+1]_66 chr11:61347876-61347956 0.00051 8_[+1]_64 chr16:89118860-89118940 0.00051 52_[+1]_20 chr19:42784540-42784620 0.00051 24_[+1]_48 chr6:158177829-158177909 0.00051 46_[+1]_26 chr12:132335922-13233600 0.00051 12_[+1]_60 chr16:710555-710635 0.00051 54_[+1]_18 chr5:171615753-171615833 0.00051 23_[+1]_49 chr14:105191441-10519152 0.00051 19_[+1]_53 chr10:135074953-13507503 0.00051 57_[+1]_15 chr19:982870-982950 0.00051 46_[+1]_26 chr22:20785405-20785485 0.00051 18_[+1]_54 chr15:40574801-40574881 0.00051 12_[+1]_60 chr7:150652765-150652845 0.00051 8_[+1]_64 chr7:2491189-2491269 0.00051 8_[+1]_64 chr19:1004830-1004910 0.00051 12_[+1]_60 chr20:32255245-32255325 0.00051 37_[+1]_35 chr3:20081509-20081589 0.00061 46_[+1]_26 chr14:96858278-96858358 0.00061 3_[+1]_69 chr1:54204430-54204510 0.00061 19_[+1]_53 chr21:44313138-44313218 0.00061 57_[+1]_15 chr9:34637704-34637784 0.00061 3_[+1]_69 chr5:96271725-96271805 0.00061 47_[+1]_25 chr16:88948911-88948991 0.00061 57_[+1]_15 chr3:152879940-152880020 0.00061 12_[+1]_60 chr6:109415978-109416058 0.00061 19_[+1]_53 chr3:150481007-150481087 0.00061 10_[+1]_62 chr10:71078244-71078324 0.00061 27_[+1]_45 chr1:33815039-33815119 0.00061 27_[+1]_45 chr1:1268534-1268614 0.00061 58_[+1]_14 chr16:84964523-84964603 0.00061 43_[+1]_29 chr11:66624076-66624156 0.00061 57_[+1]_15 chr9:139493024-139493104 0.00061 39_[+1]_33 chr7:157293807-157293887 0.00082 71_[+1]_1 chr13:41885604-41885684 0.00082 12_[+1]_60 chr12:1771153-1771233 0.00082 41_[+1]_31 chr8:144489707-144489787 0.00082 12_[+1]_60 chr7:76029726-76029806 0.00082 32_[+1]_40 chr22:29704276-29704356 0.00082 44_[+1]_28 chrX:153029586-153029666 0.00082 12_[+1]_60 chr16:88520804-88520884 0.00082 50_[+1]_22 chr20:30200751-30200831 0.001 32_[+1]_40 chr1:1823075-1823155 0.001 13_[+1]_59 chr19:13260800-13260880 0.001 70_[+1]_2 chr11:63438342-63438422 0.001 7_[+1]_65 chr13:41363579-41363659 0.001 16_[+1]_56 chr9:139001633-139001713 0.001 45_[+1]_27 chr1:23854884-23854964 0.0011 55_[+1]_17 chr8:145910361-145910441 0.0011 13_[+1]_59 chr1:226310146-226310226 0.0013 2_[+1]_70 chr6:139694951-139695031 0.0013 53_[+1]_19 chr2:242707707-242707787 0.0013 64_[+1]_8 chr11:119039579-11903965 0.0013 52_[+1]_20 chr15:40650472-40650552 0.0013 45_[+1]_27 chrX:49042878-49042958 0.0013 16_[+1]_56 chr7:158496782-158496862 0.0014 40_[+1]_32 chr20:60932393-60932473 0.0014 35_[+1]_37 chr9:139539028-139539108 0.0014 19_[+1]_53 chr12:53441411-53441491 0.0014 58_[+1]_14 chr9:34652164-34652244 0.0016 31_[+1]_41 chr14:23771378-23771458 0.0016 11_[+1]_61 chr19:15491000-15491080 0.0016 21_[+1]_51 chr16:31153824-31153904 0.0017 39_[+1]_33 chr17:7199739-7199819 0.0017 41_[+1]_31 chr19:813402-813482 0.0017 51_[+1]_21 chr19:36247707-36247787 0.0017 12_[+1]_60 chr1:27854659-27854739 0.0017 28_[+1]_44 chr19:50373302-50373382 0.0019 51_[+1]_21 chr1:115053226-115053306 0.0019 5_[+1]_67 chr10:80063107-80063187 0.0019 62_[+1]_10 chr1:32228458-32228538 0.0019 7_[+1]_65 chr9:95857808-95857888 0.0019 9_[+1]_63 chr7:150774067-150774147 0.0019 70_[+1]_2 chr4:1239386-1239466 0.0019 45_[+1]_27 chr19:18546485-18546565 0.002 45_[+1]_27 chr20:60889281-60889361 0.0021 25_[+1]_47 chr19:1021147-1021227 0.0021 15_[+1]_57 chr1:117113065-117113145 0.0021 18_[+1]_54 chr7:150706593-150706673 0.0021 68_[+1]_4 chr2:191045055-191045135 0.0021 51_[+1]_21 chr5:6633681-6633761 0.0021 8_[+1]_64 chr8:124169172-124169252 0.0021 69_[+1]_3 chr22:20136080-20136160 0.0021 61_[+1]_11 chr10:74034646-74034726 0.0022 58_[+1]_14 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YGGGCASN MEME-1 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF YGGGCASN width=8 seqs=134 chr19:952906-952986 ( 51) TGGGCACT 1 chr1:1057656-1057736 ( 33) TGGGCACT 1 chr8:141521748-141521828 ( 60) TGGGCACT 1 chr20:61675384-61675464 ( 57) TGGGCACT 1 chr16:778573-778653 ( 65) TGGGCACA 1 chr17:76111955-76112035 ( 49) TGGGCACA 1 chr17:76111750-76111830 ( 65) TGGGCACA 1 chr7:100463734-100463814 ( 28) TTGGCATA 1 chr11:62380913-62380993 ( 61) TGGGCACA 1 chr20:60889081-60889161 ( 69) TGGGCACA 1 chr20:62447372-62447452 ( 64) TGGGCACA 1 chr10:134996472-13499655 ( 23) TGGGCACA 1 chr7:129465461-129465541 ( 39) CTGGCACT 1 chr22:20785623-20785703 ( 59) CTGGCACT 1 chr1:113261503-113261583 ( 19) CTGGCACT 1 chr19:588419-588499 ( 44) CTGGCACT 1 chr5:150414226-150414306 ( 42) TGGGCATA 1 chr10:127511554-12751163 ( 71) CTGGCACA 1 chr1:3639464-3639544 ( 60) CTGGCACA 1 chr19:815473-815553 ( 68) CTGGCACA 1 chr5:179248432-179248512 ( 63) CGGGCACT 1 chr8:23082319-23082399 ( 56) CGGGCACT 1 chr4:57843233-57843313 ( 50) CGGGCACT 1 chr16:726668-726748 ( 55) CGGGCACT 1 chr17:79409130-79409210 ( 22) CGGGCACT 1 chr22:20134524-20134604 ( 28) TTGGCACC 1 chr3:122786165-122786245 ( 29) CGGGCACT 1 chr19:13113512-13113592 ( 24) CGGGCACT 1 chr10:71168694-71168774 ( 12) TTGGCACC 1 chr16:22012442-22012522 ( 14) CGGGCACT 1 chr2:176944745-176944825 ( 41) CGGGCACA 1 chr17:74497340-74497420 ( 16) CGGGCACA 1 chr1:28835426-28835506 ( 34) TTGGCAGA 1 chr12:133304152-13330423 ( 63) CGGGCACA 1 chr8:145024678-145024758 ( 73) CGGGCACA 1 chr19:1326038-1326118 ( 61) CGGGCACA 1 chr9:124132117-124132197 ( 27) TTGGCATC 1 chr11:64808772-64808852 ( 15) TGGGCACC 1 chr17:35716324-35716404 ( 61) TGGGCAGT 1 chr1:28286595-28286675 ( 65) TGGGCACC 1 chr7:23510795-23510875 ( 30) TGGGCACC 1 chr3:32148268-32148348 ( 71) TGGGCACC 1 chr9:131057713-131057793 ( 64) TGGGCACG 1 chrX:48958370-48958450 ( 29) TGGGCACG 1 chr9:94712536-94712616 ( 20) TGGGCAGA 1 chr17:38226734-38226814 ( 50) TTGGCATG 1 chr6:169250261-169250341 ( 54) TGGGCAGA 1 chr10:61666257-61666337 ( 39) CTGGCACC 1 chr16:3019934-3020014 ( 22) CTGGCACC 1 chr3:48885154-48885234 ( 61) CTGGCACC 1 chr1:16342604-16342684 ( 7) TGGGCATC 1 chr11:61347876-61347956 ( 9) CTGGCACC 1 chr16:89118860-89118940 ( 53) CTGGCACC 1 chr19:42784540-42784620 ( 25) CTGGCACC 1 chr6:158177829-158177909 ( 47) TGGGCATC 1 chr12:132335922-13233600 ( 13) CTGGCACC 1 chr16:710555-710635 ( 55) AGGGCACT 1 chr5:171615753-171615833 ( 24) AGGGCACT 1 chr14:105191441-10519152 ( 20) CTGGCAGT 1 chr10:135074953-13507503 ( 58) CTGGCACC 1 chr19:982870-982950 ( 47) CTGGCACC 1 chr22:20785405-20785485 ( 19) CTGGCAGT 1 chr15:40574801-40574881 ( 13) CTGGCAGT 1 chr7:150652765-150652845 ( 9) CTGGCAGT 1 chr7:2491189-2491269 ( 9) TGGGCATC 1 chr19:1004830-1004910 ( 13) CTGGCACC 1 chr20:32255245-32255325 ( 38) CTGGCAGT 1 chr3:20081509-20081589 ( 47) CTGGCAGA 1 chr14:96858278-96858358 ( 4) CTGGCACG 1 chr1:54204430-54204510 ( 20) TGGGCAAT 1 chr21:44313138-44313218 ( 58) AGGGCACA 1 chr9:34637704-34637784 ( 4) CTGGCACG 1 chr5:96271725-96271805 ( 48) TGGGCATG 1 chr16:88948911-88948991 ( 58) TGGGCATG 1 chr3:152879940-152880020 ( 13) TGGGCATG 1 chr6:109415978-109416058 ( 20) AGGGCACA 1 chr3:150481007-150481087 ( 11) CTGGCAGA 1 chr10:71078244-71078324 ( 28) CTGGCACG 1 chr1:33815039-33815119 ( 28) CTGGCACG 1 chr1:1268534-1268614 ( 59) TGGGCATG 1 chr16:84964523-84964603 ( 44) TGGGCATG 1 chr11:66624076-66624156 ( 58) TGGGCATG 1 chr9:139493024-139493104 ( 40) TGGGCATG 1 chr7:157293807-157293887 ( 72) CGGGCACC 1 chr13:41885604-41885684 ( 13) CGGGCACC 1 chr12:1771153-1771233 ( 42) CGGGCACC 1 chr8:144489707-144489787 ( 13) CGGGCACC 1 chr7:76029726-76029806 ( 33) CGGGCAGT 1 chr22:29704276-29704356 ( 45) TTGGCAGC 1 chrX:153029586-153029666 ( 13) TGGGCAAA 1 chr16:88520804-88520884 ( 51) CGGGCACC 1 chr20:30200751-30200831 ( 33) CGGGCAGA 1 chr1:1823075-1823155 ( 14) CGGGCAGA 1 chr19:13260800-13260880 ( 71) CGGGCACG 1 chr11:63438342-63438422 ( 8) CGGGCACG 1 chr13:41363579-41363659 ( 17) CGGGCACG 1 chr9:139001633-139001713 ( 46) CGGGCACG 1 chr1:23854884-23854964 ( 56) CGGGCATC 1 chr8:145910361-145910441 ( 14) CGGGCATC 1 chr1:226310146-226310226 ( 3) CGGGCAAT 1 chr6:139694951-139695031 ( 54) TGGGCAGG 1 chr2:242707707-242707787 ( 65) CGGGCATG 1 chr11:119039579-11903965 ( 53) TGGGCAGG 1 chr15:40650472-40650552 ( 46) CGGGCATG 1 chrX:49042878-49042958 ( 17) CGGGCATG 1 chr7:158496782-158496862 ( 41) AGGGCAGT 1 chr20:60932393-60932473 ( 36) AGGGCACC 1 chr9:139539028-139539108 ( 20) CTGGCAGC 1 chr12:53441411-53441491 ( 59) CTGGCAGC 1 chr9:34652164-34652244 ( 32) AGGGCAGA 1 chr14:23771378-23771458 ( 12) CTGGCAGG 1 chr19:15491000-15491080 ( 22) AGGGCACG 1 chr16:31153824-31153904 ( 40) CGGGCAGC 1 chr17:7199739-7199819 ( 42) TGGGCAAG 1 chr19:813402-813482 ( 52) CGGGCAGC 1 chr19:36247707-36247787 ( 13) CGGGCAGC 1 chr1:27854659-27854739 ( 29) CGGGCAGC 1 chr19:50373302-50373382 ( 52) AGGGCAAT 1 chr1:115053226-115053306 ( 6) CGGGCAGG 1 chr10:80063107-80063187 ( 63) CGGGCAGG 1 chr1:32228458-32228538 ( 8) CGGGCAGG 1 chr9:95857808-95857888 ( 10) CGGGCAGG 1 chr7:150774067-150774147 ( 71) AGGGCATG 1 chr4:1239386-1239466 ( 46) CGGGCAGG 1 chr19:18546485-18546565 ( 46) CGGGCAAC 1 chr20:60889281-60889361 ( 26) CGGGCAAG 1 chr19:1021147-1021227 ( 16) CGGGCAAG 1 chr1:117113065-117113145 ( 19) AGGGCAGC 1 chr7:150706593-150706673 ( 69) AGGGCAGC 1 chr2:191045055-191045135 ( 52) AGGGCAGC 1 chr5:6633681-6633761 ( 9) ATGGCAAC 1 chr8:124169172-124169252 ( 70) AGGGCAGG 1 chr22:20136080-20136160 ( 62) AGGGCAGG 1 chr10:74034646-74034726 ( 59) AGGGCAAG 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YGGGCASN MEME-1 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 9.09987 E= 1.6e-020 -10 62 -1371 129 -1371 -1371 92 115 -1371 -1371 142 -1371 -1371 -1371 142 -1371 -1371 148 -1371 -1371 288 -1371 -1371 -1371 -86 50 -48 19 62 -27 -44 72 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YGGGCASN MEME-1 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 134 E= 1.6e-020 0.126866 0.552239 0.000000 0.320896 0.000000 0.000000 0.708955 0.291045 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.074627 0.507463 0.268657 0.149254 0.208955 0.298507 0.276119 0.216418 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YGGGCASN MEME-1 regular expression -------------------------------------------------------------------------------- [CT][GT]GGCA[CG][CGTA] -------------------------------------------------------------------------------- Time 5.20 secs. ******************************************************************************** ******************************************************************************** MOTIF TGCCCASN MEME-2 width = 8 sites = 53 llr = 424 E-value = 1.4e-012 ******************************************************************************** -------------------------------------------------------------------------------- Motif TGCCCASN MEME-2 Description -------------------------------------------------------------------------------- Simplified A ::::2a13 pos.-specific C ::aa8:53 probability G :a::::22 matrix T a:::::22 bits 2.9 * * 2.6 * * 2.3 * * 2.1 * * Relative 1.8 * * Entropy 1.5 **** * (11.5 bits) 1.2 ****** 0.9 ****** 0.6 ****** 0.3 ****** * 0.0 -------- Multilevel TGCCCACC consensus GA sequence T G -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGCCCASN MEME-2 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr11:64126769-64126849 72 2.99e-05 TCGCCCCCTG TGCCCACA G chr19:17622906-17622986 21 2.99e-05 AAGAGGGCCG TGCCCACT GCCTGCACCT chr19:10224712-10224792 62 2.99e-05 CTGCTGGCCA TGCCCACA CTCAGCTTCT chr13:60970536-60970616 42 2.99e-05 GCGGCGCGCA TGCCCACT CAGGGACCCA chr16:89255027-89255107 44 2.99e-05 cacacacaga tgcccaca cacagatgcc chr7:73704753-73704833 69 2.99e-05 GCCGAGCGGG TGCCCACT GGGC chr20:31215029-31215109 9 2.99e-05 GCCCACAG TGCCCACA TCCCCCTCCT chr9:137230861-137230941 4 2.99e-05 CAG TGCCCACA CCGGCAGGGA chr12:132619265-13261934 18 2.99e-05 GTGCCCACGG TGCCCACT CCTCCCACCT chr19:815473-815553 58 2.99e-05 GTGGCTGCGG TGCCCACA GGCTGGCACA chr4:1389220-1389300 21 4.08e-05 CCTGCTCACG TGCCCATA TGGAGTGCCC chr7:5633461-5633541 53 4.08e-05 TCCGGAGCAC TGCCCATT GCGCCCCCGC chr17:38226734-38226814 69 4.08e-05 GGGGCAGTGC TGCCCATA GACG chr1:153919185-153919265 9 5.20e-05 CAAGCGTC TGCCCAAA GCCCAGCCGC chr19:47743011-47743091 61 5.20e-05 GCCCACCGCG TGCCCAAT GCCAGGCGGG chr3:167813530-167813610 42 5.20e-05 CCGTGCGGCC TGCCCAAT GGGTGGAAGG chr9:131102104-131102184 47 9.44e-05 GTGTCCTTTG TGCCAACA GGTGTGCCAG chrX:48958370-48958450 13 9.44e-05 GGTCTGGGAG TGCCAACA GGACGGGATG chr16:89118860-89118940 63 9.44e-05 CTGGCACCTC TGCCAACT GCTGCCGCCT chr10:52383653-52383733 72 9.44e-05 CTGCCGAGCA TGCCCAGT C chr20:60932393-60932473 64 9.44e-05 GCCCCCTCGA TGCCCAGA GTCCTGGGC chr20:47896562-47896642 62 9.44e-05 ACTCAGTAAA TGCCAACT ACTTCCTCAA chr20:36793710-36793790 57 9.44e-05 GGCCACCCAT TGCCCAGT CCCGGGCCCA chr22:50247123-50247203 31 9.44e-05 GCCGAGCCGC TGCCAACT GCCAAGCCAC chr22:29704276-29704356 6 9.44e-05 CCCTG TGCCAACA TGCCAACGCC chr16:22012442-22012522 60 9.44e-05 GCGCCGCCAC TGCCCAGA AATTGGGCGG chr10:134794148-13479422 23 9.44e-05 gcccagtgag tgcccagt gagtgcccag chr2:136289413-136289493 69 1.35e-04 CACTGCCTTG TGCCCACC GCCC chr16:1243494-1243574 63 1.35e-04 GCTGTGGCCT TGCCCACC TATGGGACAG chr19:952906-952986 35 1.35e-04 CCTTGGGCAC TGCCCACC TGTGACCTTG chr14:104314558-10431463 44 1.35e-04 GTGCCACCTG TGCCCACC TGCGCCAGCA chr17:79894744-79894824 70 1.35e-04 CGCAGCCGGG TGCCCACC TCC chr19:3388004-3388084 58 1.53e-04 GCCCAGATGG TGCCCATC TGCTGACGCC chr1:23854884-23854964 37 2.00e-04 AGGGCAGGCC TGCCCACG GGGCTGGGCC chr19:1466053-1466133 56 2.00e-04 CGACGGGTAC TGCCCACG CGAACATATG chr19:1482248-1482328 47 2.00e-04 ACATGCACGC TGCCCACG GTGGCCGCCA chr17:80194438-80194518 26 2.00e-04 TCGGGGAGCC TGCCCACG GGGTGCCCCT chr21:46554070-46554150 17 2.15e-04 GCTGGGTGTG TGCCCAAC AGTGGTGTGT chr17:17875297-17875377 17 2.15e-04 ACGACCAGGA TGCCCAAC CCGCCCGTGA chr7:158496782-158496862 8 2.42e-04 AGGGTAG TGCCCATG CCCAGGACTG chr7:129465461-129465541 54 2.42e-04 ACTGCGGCAG TGCCCATG TCAGCTCTGG chr6:139694951-139695031 43 2.42e-04 AACTGCCCCA TGCCCATG CGGTGGGCAG chr7:150652765-150652845 48 2.42e-04 TGGCTCGAGC TGCCCATG GCCCCGTGGC chr1:54871071-54871151 21 2.99e-04 CCACCGTCGC TGCCCAGC CCGGCGTCCG chr16:21313040-21313120 53 2.99e-04 AGGGCCAGGC TGCCAACC TGCCCGCGGG chr1:36787934-36788014 24 2.99e-04 AGCGTGCCTG TGCCCAGC AGGTCCGGCT chr5:153569895-153569975 60 2.99e-04 CACCCAGCGG TGCCCAGC CCGCACCAGT chr10:127511554-12751163 56 2.99e-04 CGCGGGACCG TGCCCAGC ACCCGGCCTG chr19:13260800-13260880 59 2.99e-04 CCGACGGCCT TGCCCAGC CCGCCGGGCA chr9:139001633-139001713 55 2.99e-04 CCGGGCACGC TGCCCAGC TGGGCTGGGG chr8:124169172-124169252 40 3.20e-04 CGACGGCCAG TGCCcaag ggcaagggca chr11:63438342-63438422 45 3.79e-04 CGCCCGGCTC TGCCCAGG GCGGGGCTCG chr17:76124728-76124808 57 4.29e-04 CGGCTCTCCT TGCCAAGG GAGTGGCAAA -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGCCCASN MEME-2 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr11:64126769-64126849 3e-05 71_[+2]_1 chr19:17622906-17622986 3e-05 20_[+2]_52 chr19:10224712-10224792 3e-05 61_[+2]_11 chr13:60970536-60970616 3e-05 41_[+2]_31 chr16:89255027-89255107 3e-05 43_[+2]_29 chr7:73704753-73704833 3e-05 68_[+2]_4 chr20:31215029-31215109 3e-05 8_[+2]_64 chr9:137230861-137230941 3e-05 3_[+2]_69 chr12:132619265-13261934 3e-05 17_[+2]_55 chr19:815473-815553 3e-05 57_[+2]_15 chr4:1389220-1389300 4.1e-05 20_[+2]_52 chr7:5633461-5633541 4.1e-05 52_[+2]_20 chr17:38226734-38226814 4.1e-05 68_[+2]_4 chr1:153919185-153919265 5.2e-05 8_[+2]_64 chr19:47743011-47743091 5.2e-05 60_[+2]_12 chr3:167813530-167813610 5.2e-05 41_[+2]_31 chr9:131102104-131102184 9.4e-05 46_[+2]_26 chrX:48958370-48958450 9.4e-05 12_[+2]_60 chr16:89118860-89118940 9.4e-05 62_[+2]_10 chr10:52383653-52383733 9.4e-05 71_[+2]_1 chr20:60932393-60932473 9.4e-05 63_[+2]_9 chr20:47896562-47896642 9.4e-05 61_[+2]_11 chr20:36793710-36793790 9.4e-05 56_[+2]_16 chr22:50247123-50247203 9.4e-05 30_[+2]_42 chr22:29704276-29704356 9.4e-05 5_[+2]_67 chr16:22012442-22012522 9.4e-05 59_[+2]_13 chr10:134794148-13479422 9.4e-05 22_[+2]_50 chr2:136289413-136289493 0.00013 68_[+2]_4 chr16:1243494-1243574 0.00013 62_[+2]_10 chr19:952906-952986 0.00013 34_[+2]_38 chr14:104314558-10431463 0.00013 43_[+2]_29 chr17:79894744-79894824 0.00013 69_[+2]_3 chr19:3388004-3388084 0.00015 57_[+2]_15 chr1:23854884-23854964 0.0002 36_[+2]_36 chr19:1466053-1466133 0.0002 55_[+2]_17 chr19:1482248-1482328 0.0002 46_[+2]_26 chr17:80194438-80194518 0.0002 25_[+2]_47 chr21:46554070-46554150 0.00021 16_[+2]_56 chr17:17875297-17875377 0.00021 16_[+2]_56 chr7:158496782-158496862 0.00024 7_[+2]_65 chr7:129465461-129465541 0.00024 53_[+2]_19 chr6:139694951-139695031 0.00024 42_[+2]_30 chr7:150652765-150652845 0.00024 47_[+2]_25 chr1:54871071-54871151 0.0003 20_[+2]_52 chr16:21313040-21313120 0.0003 52_[+2]_20 chr1:36787934-36788014 0.0003 23_[+2]_49 chr5:153569895-153569975 0.0003 59_[+2]_13 chr10:127511554-12751163 0.0003 55_[+2]_17 chr19:13260800-13260880 0.0003 58_[+2]_14 chr9:139001633-139001713 0.0003 54_[+2]_18 chr8:124169172-124169252 0.00032 39_[+2]_33 chr11:63438342-63438422 0.00038 44_[+2]_28 chr17:76124728-76124808 0.00043 56_[+2]_16 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGCCCASN MEME-2 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF TGCCCASN width=8 seqs=53 chr11:64126769-64126849 ( 72) TGCCCACA 1 chr19:17622906-17622986 ( 21) TGCCCACT 1 chr19:10224712-10224792 ( 62) TGCCCACA 1 chr13:60970536-60970616 ( 42) TGCCCACT 1 chr16:89255027-89255107 ( 44) TGCCCACA 1 chr7:73704753-73704833 ( 69) TGCCCACT 1 chr20:31215029-31215109 ( 9) TGCCCACA 1 chr9:137230861-137230941 ( 4) TGCCCACA 1 chr12:132619265-13261934 ( 18) TGCCCACT 1 chr19:815473-815553 ( 58) TGCCCACA 1 chr4:1389220-1389300 ( 21) TGCCCATA 1 chr7:5633461-5633541 ( 53) TGCCCATT 1 chr17:38226734-38226814 ( 69) TGCCCATA 1 chr1:153919185-153919265 ( 9) TGCCCAAA 1 chr19:47743011-47743091 ( 61) TGCCCAAT 1 chr3:167813530-167813610 ( 42) TGCCCAAT 1 chr9:131102104-131102184 ( 47) TGCCAACA 1 chrX:48958370-48958450 ( 13) TGCCAACA 1 chr16:89118860-89118940 ( 63) TGCCAACT 1 chr10:52383653-52383733 ( 72) TGCCCAGT 1 chr20:60932393-60932473 ( 64) TGCCCAGA 1 chr20:47896562-47896642 ( 62) TGCCAACT 1 chr20:36793710-36793790 ( 57) TGCCCAGT 1 chr22:50247123-50247203 ( 31) TGCCAACT 1 chr22:29704276-29704356 ( 6) TGCCAACA 1 chr16:22012442-22012522 ( 60) TGCCCAGA 1 chr10:134794148-13479422 ( 23) TGCCCAGT 1 chr2:136289413-136289493 ( 69) TGCCCACC 1 chr16:1243494-1243574 ( 63) TGCCCACC 1 chr19:952906-952986 ( 35) TGCCCACC 1 chr14:104314558-10431463 ( 44) TGCCCACC 1 chr17:79894744-79894824 ( 70) TGCCCACC 1 chr19:3388004-3388084 ( 58) TGCCCATC 1 chr1:23854884-23854964 ( 37) TGCCCACG 1 chr19:1466053-1466133 ( 56) TGCCCACG 1 chr19:1482248-1482328 ( 47) TGCCCACG 1 chr17:80194438-80194518 ( 26) TGCCCACG 1 chr21:46554070-46554150 ( 17) TGCCCAAC 1 chr17:17875297-17875377 ( 17) TGCCCAAC 1 chr7:158496782-158496862 ( 8) TGCCCATG 1 chr7:129465461-129465541 ( 54) TGCCCATG 1 chr6:139694951-139695031 ( 43) TGCCCATG 1 chr7:150652765-150652845 ( 48) TGCCCATG 1 chr1:54871071-54871151 ( 21) TGCCCAGC 1 chr16:21313040-21313120 ( 53) TGCCAACC 1 chr1:36787934-36788014 ( 24) TGCCCAGC 1 chr5:153569895-153569975 ( 60) TGCCCAGC 1 chr10:127511554-12751163 ( 56) TGCCCAGC 1 chr19:13260800-13260880 ( 59) TGCCCAGC 1 chr9:139001633-139001713 ( 55) TGCCCAGC 1 chr8:124169172-124169252 ( 40) TGCCCAAG 1 chr11:63438342-63438422 ( 45) TGCCCAGG 1 chr17:76124728-76124808 ( 57) TGCCAAGG 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGCCCASN MEME-2 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 10.0668 E= 1.4e-012 -1237 -1237 -1237 293 -1237 -1237 142 -1237 -1237 148 -1237 -1237 -1237 148 -1237 -1237 15 124 -1237 -1237 288 -1237 -1237 -1237 -26 45 -61 20 96 -35 -85 90 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGCCCASN MEME-2 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 53 E= 1.4e-012 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.150943 0.849057 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.113208 0.490566 0.245283 0.150943 0.264151 0.283019 0.207547 0.245283 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGCCCASN MEME-2 regular expression -------------------------------------------------------------------------------- TGCCCA[CG][CATG] -------------------------------------------------------------------------------- Time 8.84 secs. ******************************************************************************** ******************************************************************************** MOTIF AGSTGSCA MEME-3 width = 8 sites = 18 llr = 168 E-value = 1.3e+002 ******************************************************************************** -------------------------------------------------------------------------------- Motif AGSTGSCA MEME-3 Description -------------------------------------------------------------------------------- Simplified A a1:::::a pos.-specific C ::4::3a: probability G :96:a5:: matrix T :::a:2:: bits 2.9 * * * 2.6 * * * 2.3 * * * 2.1 * * * Relative 1.8 * * * Entropy 1.5 * ** ** (13.5 bits) 1.2 ** ** ** 0.9 ** ** ** 0.6 ***** ** 0.3 ******** 0.0 -------- Multilevel AGGTGGCA consensus C C sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AGSTGSCA MEME-3 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr1:51434731-51434811 40 1.71e-05 GGACCGCGAG AGGTGGCA AAGTGGCACC chr1:117113065-117113145 44 1.71e-05 GCCCTCGAGC AGGTGGCA TCCGCGCCCG chr12:132335922-13233600 65 1.71e-05 GGGCAGGCTC AGGTGGCA AGGACGGA chr9:139907670-139907750 24 1.71e-05 TTGAGCACGC AGGTGGCA CCCACCCCCG chr6:169250261-169250341 13 1.71e-05 TTGTGGGAAG AGGTGGCA TGGGCCTTGT chr19:815473-815553 40 1.71e-05 ATGTTCACCG AGGTGGCA GTGGCTGCGG chr17:17875297-17875377 34 1.71e-05 CCCGCCCGTG AGGTGGCA CCGACGCCCA chr9:131057713-131057793 53 2.30e-05 CAGCTCTCCC AGGTGTCA TAGTGGGCAC chr9:35749126-35749206 39 3.95e-05 GCCCGCGCCC AGGTGCCA GCCCGTGGGA chr11:119039579-11903965 23 3.95e-05 GCCCGCTGCC AGGTGCCA GGGCCGCGCA chr3:150481007-150481087 56 5.59e-05 GCCCGGCTCC AGCTGGCA GCGCAGGGGG chr19:39898573-39898653 42 6.17e-05 CTGGGCCCTG AGCTGTCA CCCTCACCCA chr5:115177868-115177948 70 6.17e-05 GGCGCTCGCC AGCTGTCA GCC chr19:17416316-17416396 25 7.75e-05 CGCTTCCTGC AGCTGCCA CCAGCTGCGC chr16:3019934-3020014 50 7.75e-05 GCGGTGACAA AGCTGCCA TTGTCCCGGG chr10:74034646-74034726 67 7.75e-05 GCAGGGCAAG AGCTGCCA CAGCGT chr19:3388004-3388084 22 7.75e-05 CCGTCCCAGC AGCTGCCA GCCCGCCCCG chr16:699300-699380 19 8.37e-05 GTAATGGCGG AAGTGGCA CCGTTGCCAG -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AGSTGSCA MEME-3 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr1:51434731-51434811 1.7e-05 39_[+3]_33 chr1:117113065-117113145 1.7e-05 43_[+3]_29 chr12:132335922-13233600 1.7e-05 64_[+3]_8 chr9:139907670-139907750 1.7e-05 23_[+3]_49 chr6:169250261-169250341 1.7e-05 12_[+3]_60 chr19:815473-815553 1.7e-05 39_[+3]_33 chr17:17875297-17875377 1.7e-05 33_[+3]_39 chr9:131057713-131057793 2.3e-05 52_[+3]_20 chr9:35749126-35749206 3.9e-05 38_[+3]_34 chr11:119039579-11903965 3.9e-05 22_[+3]_50 chr3:150481007-150481087 5.6e-05 55_[+3]_17 chr19:39898573-39898653 6.2e-05 41_[+3]_31 chr5:115177868-115177948 6.2e-05 69_[+3]_3 chr19:17416316-17416396 7.7e-05 24_[+3]_48 chr16:3019934-3020014 7.7e-05 49_[+3]_23 chr10:74034646-74034726 7.7e-05 66_[+3]_6 chr19:3388004-3388084 7.7e-05 21_[+3]_51 chr16:699300-699380 8.4e-05 18_[+3]_54 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AGSTGSCA MEME-3 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF AGSTGSCA width=8 seqs=18 chr1:51434731-51434811 ( 40) AGGTGGCA 1 chr1:117113065-117113145 ( 44) AGGTGGCA 1 chr12:132335922-13233600 ( 65) AGGTGGCA 1 chr9:139907670-139907750 ( 24) AGGTGGCA 1 chr6:169250261-169250341 ( 13) AGGTGGCA 1 chr19:815473-815553 ( 40) AGGTGGCA 1 chr17:17875297-17875377 ( 34) AGGTGGCA 1 chr9:131057713-131057793 ( 53) AGGTGTCA 1 chr9:35749126-35749206 ( 39) AGGTGCCA 1 chr11:119039579-11903965 ( 23) AGGTGCCA 1 chr3:150481007-150481087 ( 56) AGCTGGCA 1 chr19:39898573-39898653 ( 42) AGCTGTCA 1 chr5:115177868-115177948 ( 70) AGCTGTCA 1 chr19:17416316-17416396 ( 25) AGCTGCCA 1 chr16:3019934-3020014 ( 50) AGCTGCCA 1 chr10:74034646-74034726 ( 67) AGCTGCCA 1 chr19:3388004-3388084 ( 22) AGCTGCCA 1 chr16:699300-699380 ( 19) AAGTGGCA 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AGSTGSCA MEME-3 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 10.8329 E= 1.3e+002 288 -1081 -1081 -1081 -129 -1081 134 -1081 -1081 11 71 -1081 -1081 -1081 -1081 293 -1081 -1081 142 -1081 -1081 -11 42 35 -1081 148 -1081 -1081 288 -1081 -1081 -1081 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AGSTGSCA MEME-3 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 18 E= 1.3e+002 1.000000 0.000000 0.000000 0.000000 0.055556 0.000000 0.944444 0.000000 0.000000 0.388889 0.611111 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.333333 0.500000 0.166667 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AGSTGSCA MEME-3 regular expression -------------------------------------------------------------------------------- AG[GC]TG[GC]CA -------------------------------------------------------------------------------- Time 12.36 secs. ******************************************************************************** ******************************************************************************** MOTIF TTGTAWWA MEME-4 width = 8 sites = 2 llr = 27 E-value = 3.1e+003 ******************************************************************************** -------------------------------------------------------------------------------- Motif TTGTAWWA MEME-4 Description -------------------------------------------------------------------------------- Simplified A ::::a55a pos.-specific C :::::::: probability G ::a::::: matrix T aa:a:55: bits 2.9 ** ** * 2.6 ** ** * 2.3 ** ** * 2.1 ** ***** Relative 1.8 ** ***** Entropy 1.5 ******** (19.8 bits) 1.2 ******** 0.9 ******** 0.6 ******** 0.3 ******** 0.0 -------- Multilevel TTGTAAAA consensus TT sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTGTAWWA MEME-4 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr11:65269791-65269871 62 2.67e-07 ATGGTAGCTT TTGTATTA TCAAGTAAGA chr1:23854884-23854964 8 1.11e-06 CACGCCC TTGTAAAA TGAGTAAGCA -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTGTAWWA MEME-4 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr11:65269791-65269871 2.7e-07 61_[+4]_11 chr1:23854884-23854964 1.1e-06 7_[+4]_65 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTGTAWWA MEME-4 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF TTGTAWWA width=8 seqs=2 chr11:65269791-65269871 ( 62) TTGTATTA 1 chr1:23854884-23854964 ( 8) TTGTAAAA 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTGTAWWA MEME-4 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 12.3073 E= 3.1e+003 -765 -765 -765 293 -765 -765 -765 293 -765 -765 142 -765 -765 -765 -765 293 288 -765 -765 -765 188 -765 -765 193 188 -765 -765 193 288 -765 -765 -765 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTGTAWWA MEME-4 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 2 E= 3.1e+003 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 1.000000 1.000000 0.000000 0.000000 0.000000 0.500000 0.000000 0.000000 0.500000 0.500000 0.000000 0.000000 0.500000 1.000000 0.000000 0.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTGTAWWA MEME-4 regular expression -------------------------------------------------------------------------------- TTGTA[AT][AT]A -------------------------------------------------------------------------------- Time 15.85 secs. ******************************************************************************** ******************************************************************************** MOTIF TTTCYTTT MEME-5 width = 8 sites = 7 llr = 73 E-value = 8.2e+003 ******************************************************************************** -------------------------------------------------------------------------------- Motif TTTCYTTT MEME-5 Description -------------------------------------------------------------------------------- Simplified A :::::::1 pos.-specific C 1::9633: probability G :1:::::: matrix T 99a14779 bits 2.9 * 2.6 * 2.3 * * 2.1 *** * Relative 1.8 *** *** Entropy 1.5 *** *** (15.0 bits) 1.2 ******** 0.9 ******** 0.6 ******** 0.3 ******** 0.0 -------- Multilevel TTTCCTTT consensus TCC sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTTCYTTT MEME-5 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr1:28835426-28835506 4 9.80e-07 TTT TTTTTTTT AACAGGGAGG chr9:131057713-131057793 26 2.78e-06 CCTTGGTCTG TTTCTCTT GTGTGAGCTC chr11:65269791-65269871 43 2.78e-06 CCTGAAGGGA TTTCTTCT GATGGTAGCT chrX:48958370-48958450 69 3.46e-06 GGAGGGGCTC TTTCCTTA CCCC chr20:30200751-30200831 6 1.23e-05 CCCGT CTTCCTTT GGCCACCAGC chr9:131102104-131102184 38 1.44e-05 TCCAAATCCG TGTCCTTT GTGCCAACAG chr19:41833680-41833760 47 2.83e-05 GAGCCCACAG TTTCCCCT CCCCGCCCTG -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTTCYTTT MEME-5 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr1:28835426-28835506 9.8e-07 3_[+5]_69 chr9:131057713-131057793 2.8e-06 25_[+5]_47 chr11:65269791-65269871 2.8e-06 42_[+5]_30 chrX:48958370-48958450 3.5e-06 68_[+5]_4 chr20:30200751-30200831 1.2e-05 5_[+5]_67 chr9:131102104-131102184 1.4e-05 37_[+5]_35 chr19:41833680-41833760 2.8e-05 46_[+5]_26 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTTCYTTT MEME-5 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF TTTCYTTT width=8 seqs=7 chr1:28835426-28835506 ( 4) TTTTTTTT 1 chr9:131057713-131057793 ( 26) TTTCTCTT 1 chr11:65269791-65269871 ( 43) TTTCTTCT 1 chrX:48958370-48958450 ( 69) TTTCCTTA 1 chr20:30200751-30200831 ( 6) CTTCCTTT 1 chr9:131102104-131102184 ( 38) TGTCCTTT 1 chr19:41833680-41833760 ( 47) TTTCCCCT 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTTCYTTT MEME-5 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 12.5704 E= 8.2e+003 -945 -133 -945 271 -945 -945 -138 271 -945 -945 -945 293 -945 125 -945 12 -945 67 -945 171 -945 -33 -945 244 -945 -33 -945 244 8 -945 -945 271 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTTCYTTT MEME-5 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 7 E= 8.2e+003 0.000000 0.142857 0.000000 0.857143 0.000000 0.000000 0.142857 0.857143 0.000000 0.000000 0.000000 1.000000 0.000000 0.857143 0.000000 0.142857 0.000000 0.571429 0.000000 0.428571 0.000000 0.285714 0.000000 0.714286 0.000000 0.285714 0.000000 0.714286 0.142857 0.000000 0.000000 0.857143 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTTCYTTT MEME-5 regular expression -------------------------------------------------------------------------------- TTTC[CT][TC][TC]T -------------------------------------------------------------------------------- Time 19.32 secs. ******************************************************************************** ******************************************************************************** SUMMARY OF MOTIFS ******************************************************************************** -------------------------------------------------------------------------------- Combined block diagrams: non-overlapping sites with p-value < 0.0001 -------------------------------------------------------------------------------- SEQUENCE NAME COMBINED P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr4:1239386-1239466 6.16e-01 80 chr19:1326038-1326118 4.08e-01 80 chr8:145024678-145024758 1.41e-01 80 chr19:588419-588499 2.61e-03 43_[+1(6.86e-05)]_29 chr20:32255245-32255325 2.28e-01 80 chr17:17875297-17875377 5.32e-03 33_[+3(1.71e-05)]_39 chr12:133304152-13330423 1.82e-01 80 chr3:15373345-15373425 7.38e-01 80 chr19:3388004-3388084 2.11e-02 21_[+3(7.75e-05)]_51 chr10:134996472-13499655 4.56e-02 7_[+1(4.77e-05)]_7_[+1(4.77e-05)]_\ 50 chr1:113261503-113261583 5.14e-02 18_[+1(6.86e-05)]_54 chr20:62447372-62447452 1.04e-01 8_[+1(4.77e-05)]_37_[+1(4.77e-05)]_\ 2_[+1(4.77e-05)]_9 chr20:61922719-61922799 3.84e-01 80 chr16:88520804-88520884 1.34e-01 80 chr21:45354840-45354920 4.23e-01 80 chr16:88941503-88941583 3.45e-01 80 chr19:815473-815553 7.67e-05 8_[+1(9.04e-05)]_23_[+3(1.71e-05)]_\ 10_[+2(2.99e-05)]_2_[+1(9.04e-05)]_5 chr6:169250261-169250341 2.72e-03 12_[+3(1.71e-05)]_16_[+3(1.71e-05)]_\ 16_[+3(1.71e-05)]_12 chr9:139493024-139493104 7.07e-01 80 chr20:60889081-60889161 1.07e-01 18_[+1(4.77e-05)]_16_[+1(4.77e-05)]_\ 18_[+1(4.77e-05)]_4 chr22:19746260-19746340 5.40e-01 80 chr10:134794148-13479422 1.82e-01 11_[+2(9.44e-05)]_3_[+2(9.44e-05)]_\ 50 chr16:88503933-88504013 6.98e-01 80 chr16:22012442-22012522 2.69e-02 59_[+2(9.44e-05)]_13 chr5:1227127-1227207 9.28e-01 80 chr20:61675384-61675464 1.50e-01 56_[+1(2.91e-05)]_16 chr11:66624076-66624156 2.57e-01 80 chr10:71168694-71168774 1.72e-01 80 chr9:139001633-139001713 3.68e-02 80 chr21:46553871-46553951 9.87e-01 80 chr22:20136080-20136160 7.18e-01 80 chr3:32148268-32148348 2.71e-01 80 chrX:153029586-153029666 2.26e-01 80 chr13:41363579-41363659 8.46e-01 80 chr22:20785623-20785703 6.32e-02 58_[+1(6.86e-05)]_14 chr11:63438342-63438422 2.06e-01 80 chr17:76127758-76127838 1.32e-01 80 chr11:62380913-62380993 4.92e-02 60_[+1(4.77e-05)]_12 chr16:84964523-84964603 1.98e-01 80 chr6:137113099-137113179 1.26e-01 80 chr8:145910361-145910441 2.40e-02 80 chr7:150774067-150774147 3.11e-01 80 chr19:1003404-1003484 6.31e-01 80 chr1:2025972-2026052 4.52e-01 80 chr1:27854659-27854739 1.58e-01 80 chr22:29704276-29704356 1.43e-02 5_[+2(9.44e-05)]_67 chr19:1004830-1004910 2.09e-01 80 chr7:76029726-76029806 4.76e-02 80 chr7:2491189-2491269 2.60e-02 80 chr8:142397009-142397089 4.32e-01 80 chr12:53441411-53441491 6.67e-02 56_[+3(5.59e-05)]_16 chr17:80194438-80194518 3.25e-01 80 chr9:139539028-139539108 2.81e-01 80 chr1:1268534-1268614 4.47e-02 80 chr12:132619265-13261934 1.10e-01 17_[+2(2.99e-05)]_55 chr19:36247707-36247787 3.28e-01 80 chr19:17393512-17393592 9.18e-01 80 chr22:50247123-50247203 2.30e-02 30_[+2(9.44e-05)]_42 chr8:141521748-141521828 3.17e-04 59_[+1(2.91e-05)]_13 chr7:150652765-150652845 1.45e-02 80 chrX:49042878-49042958 5.24e-02 80 chr2:153572551-153572631 1.29e-02 80 chr7:100463734-100463814 1.66e-03 27_[+1(4.77e-05)]_45 chr2:208634536-208634616 8.25e-01 80 chr19:13113512-13113592 5.35e-02 80 chr1:33815039-33815119 4.47e-01 80 chr12:105629681-10562976 7.30e-01 80 chr9:139907670-139907750 1.27e-02 23_[+3(1.71e-05)]_49 chr17:38226734-38226814 6.57e-03 68_[+2(4.08e-05)]_4 chr3:128207425-128207505 7.66e-01 80 chr20:36793710-36793790 1.50e-01 56_[+2(9.44e-05)]_16 chr19:13260800-13260880 3.46e-02 80 chr3:122786165-122786245 2.08e-01 80 chr10:13342069-13342149 7.42e-01 80 chr15:40650472-40650552 2.81e-01 80 chr1:3639464-3639544 3.25e-02 59_[+1(9.04e-05)]_13 chr19:1482248-1482328 3.25e-01 80 chr1:28835426-28835506 6.20e-06 [+5(9.80e-07)]_72 chr10:127511554-12751163 1.52e-02 70_[+1(9.04e-05)]_2 chr15:40574801-40574881 2.35e-01 80 chr3:167813530-167813610 8.33e-02 41_[+2(5.20e-05)]_31 chr17:74497340-74497420 3.97e-01 80 chr7:150068534-150068614 2.81e-01 80 chr17:80036466-80036546 7.75e-01 80 chr22:20134524-20134604 8.65e-02 80 chr1:1823075-1823155 6.02e-01 80 chr9:137230861-137230941 3.68e-02 3_[+2(2.99e-05)]_69 chr22:20785405-20785485 1.90e-01 80 chr7:36192732-36192812 6.96e-01 80 chr17:44896299-44896379 8.16e-01 80 chr21:46554070-46554150 3.48e-01 80 chr10:71078244-71078324 3.71e-01 80 chr8:120886251-120886331 7.12e-01 80 chr20:31215029-31215109 2.43e-02 8_[+2(2.99e-05)]_64 chr11:119039579-11903965 2.19e-02 22_[+3(3.95e-05)]_50 chr19:982870-982950 1.78e-01 80 chr20:47896562-47896642 1.31e-05 10_[+4(1.78e-05)]_43_[+2(9.44e-05)]_\ 11 chr4:1007167-1007247 3.25e-01 80 chr9:95857808-95857888 7.63e-01 80 chr8:144489707-144489787 7.11e-02 80 chr19:46289225-46289305 8.77e-01 80 chr17:52978037-52978117 8.06e-01 80 chr7:73704753-73704833 2.00e-02 68_[+2(2.99e-05)]_4 chr17:76111750-76111830 1.07e-01 1_[+1(4.77e-05)]_13_[+1(4.77e-05)]_\ 13_[+1(4.77e-05)]_13_[+1(4.77e-05)]_8 chr5:115177868-115177948 2.54e-03 69_[+3(6.17e-05)]_3 chr10:135074953-13507503 1.95e-02 80 chr17:79409130-79409210 2.08e-01 80 chr3:150481007-150481087 4.53e-02 55_[+3(5.59e-05)]_17 chr2:191045055-191045135 1.87e-01 80 chr16:2867178-2867258 5.92e-01 80 chr10:121302330-12130241 8.85e-01 80 chr7:23510795-23510875 4.98e-01 80 chr20:36013153-36013233 6.68e-01 80 chr2:242707707-242707787 5.97e-01 80 chrX:38663246-38663326 5.71e-01 80 chr12:1771153-1771233 3.26e-01 80 chrX:153191838-153191918 3.41e-01 80 chr17:79894744-79894824 9.88e-02 80 chr16:89255027-89255107 4.90e-02 43_[+2(2.99e-05)]_29 chr19:18546485-18546565 5.44e-01 80 chr6:109415978-109416058 1.26e-01 80 chr19:18547820-18547900 8.13e-01 80 chr4:1750619-1750699 7.03e-03 80 chr10:126298991-12629907 9.99e-01 80 chr11:65269791-65269871 3.69e-06 42_[+5(2.78e-06)]_11_[+4(2.67e-07)]_\ 11 chr3:152879940-152880020 4.19e-01 80 chr16:88948911-88948991 3.45e-01 80 chr14:105191441-10519152 9.37e-02 80 chr19:39898573-39898653 4.44e-02 41_[+3(6.17e-05)]_31 chr17:76310351-76310431 3.79e-01 80 chr15:58358600-58358680 6.42e-01 80 chr2:10091265-10091345 9.87e-01 80 chr14:104314558-10431463 1.42e-01 80 chr1:28286595-28286675 4.01e-01 80 chr13:60970536-60970616 1.85e-01 41_[+2(2.99e-05)]_31 chr9:139128806-139128886 2.04e-01 80 chr16:23847888-23847968 3.85e-01 80 chr17:35716324-35716404 3.93e-01 80 chr20:30200751-30200831 4.34e-03 5_[+5(1.23e-05)]_67 chr19:813402-813482 3.56e-01 80 chr5:171615753-171615833 2.54e-01 80 chr13:41885604-41885684 4.13e-01 80 chr19:940864-940944 7.81e-01 80 chr11:94277409-94277489 3.48e-01 80 chr3:195603617-195603697 6.05e-01 80 chr16:710555-710635 3.03e-02 80 chr7:150706593-150706673 1.87e-01 80 chr13:103425966-10342604 4.72e-01 80 chr12:132335922-13233600 1.32e-02 64_[+3(1.71e-05)]_8 chr19:10224712-10224792 1.22e-01 61_[+2(2.99e-05)]_11 chr7:157293807-157293887 3.23e-01 80 chr20:60932393-60932473 1.24e-01 63_[+2(9.44e-05)]_9 chr16:67563064-67563144 6.39e-01 80 chr16:699300-699380 3.08e-02 18_[+3(8.37e-05)]_54 chr1:117113065-117113145 5.04e-02 43_[+3(1.71e-05)]_29 chr19:17622906-17622986 1.04e-01 20_[+2(2.99e-05)]_52 chr6:139694951-139695031 2.78e-02 80 chr5:153569895-153569975 3.17e-01 80 chr11:64126769-64126849 4.60e-02 71_[+2(2.99e-05)]_1 chr6:158177829-158177909 3.27e-01 80 chr1:32228458-32228538 2.58e-01 80 chr7:5633461-5633541 4.60e-02 52_[+2(4.08e-05)]_20 chr19:1021147-1021227 5.94e-01 80 chr10:52383653-52383733 3.56e-02 71_[+2(9.44e-05)]_1 chr16:726668-726748 6.21e-02 80 chr19:41833680-41833760 1.58e-02 46_[+5(2.83e-05)]_26 chr5:137802151-137802231 9.79e-01 80 chr20:5986627-5986707 9.04e-02 60_[+4(4.53e-05)]_12 chr19:41173098-41173178 1.72e-02 80 chr1:1057656-1057736 1.79e-02 32_[+1(2.91e-05)]_40 chr16:85286874-85286954 6.34e-01 80 chr2:220041686-220041766 5.62e-01 80 chr17:76111955-76112035 7.90e-02 6_[+1(4.77e-05)]_13_[+1(4.77e-05)]_\ 13_[+1(4.77e-05)]_24 chr9:94712536-94712616 4.50e-01 80 chr19:42784540-42784620 1.63e-01 80 chr16:89118860-89118940 7.92e-03 62_[+2(9.44e-05)]_10 chr17:79700958-79701038 1.89e-01 80 chrX:48958370-48958450 8.77e-06 12_[+2(9.44e-05)]_48_[+5(3.46e-06)]_\ 4 chr17:7199739-7199819 1.72e-01 80 chr10:80063107-80063187 9.41e-02 80 chr4:1389220-1389300 9.08e-03 20_[+2(4.08e-05)]_52 chr5:96271725-96271805 1.71e-01 80 chr11:61347876-61347956 1.68e-01 80 chr11:67071012-67071092 5.03e-01 80 chr9:34637704-34637784 3.38e-01 80 chr1:16342604-16342684 2.58e-01 80 chr21:44313138-44313218 4.33e-01 80 chr7:129465461-129465541 4.98e-03 38_[+1(6.86e-05)]_34 chr19:47743011-47743091 1.18e-01 60_[+2(5.20e-05)]_12 chr1:153919185-153919265 1.01e-01 8_[+2(5.20e-05)]_64 chr19:952906-952986 4.27e-03 27_[+1(2.91e-05)]_15_[+1(2.91e-05)]_\ 22 chr10:74034646-74034726 8.07e-02 66_[+3(7.75e-05)]_6 chr19:39522676-39522756 7.21e-01 80 chr19:1466053-1466133 5.39e-02 80 chr3:48936272-48936352 3.66e-01 80 chr16:31153824-31153904 5.66e-01 80 chr3:48885154-48885234 6.32e-02 80 chr9:131102104-131102184 6.92e-04 37_[+5(1.44e-05)]_1_[+2(9.44e-05)]_\ 26 chr16:1243494-1243574 3.35e-02 80 chr22:19511394-19511474 9.20e-01 80 chr7:158496782-158496862 9.09e-02 80 chr16:3019934-3020014 1.77e-02 49_[+3(7.75e-05)]_23 chr1:228559093-228559173 7.40e-02 80 chr19:14584495-14584575 9.26e-01 80 chr5:2038837-2038917 9.49e-01 80 chr9:131872926-131873006 8.87e-01 80 chr20:60889281-60889361 1.57e-01 80 chr19:15491000-15491080 3.72e-01 80 chr19:17799114-17799194 6.20e-01 80 chr8:124169172-124169252 2.58e-01 80 chr1:115053226-115053306 6.84e-01 80 chr1:54204430-54204510 4.79e-02 80 chr1:23854884-23854964 1.03e-04 7_[+4(1.11e-06)]_65 chr1:51434731-51434811 8.76e-03 39_[+3(1.71e-05)]_[+3(8.37e-05)]_25 chr14:96858278-96858358 3.36e-01 80 chr13:53024743-53024823 9.84e-01 80 chr2:227656318-227656398 2.44e-01 80 chr1:226310146-226310226 2.53e-01 80 chr9:131057713-131057793 1.55e-06 25_[+5(2.78e-06)]_19_[+3(2.30e-05)]_\ 20 chr17:76124728-76124808 4.62e-02 80 chr9:35749126-35749206 1.15e-01 38_[+3(3.95e-05)]_34 chr1:36787934-36788014 3.30e-01 80 chr19:50373302-50373382 7.76e-01 80 chr4:95373395-95373475 6.28e-01 80 chr11:64808772-64808852 1.35e-01 80 chr16:778573-778653 2.79e-02 64_[+1(4.77e-05)]_8 chr5:150414226-150414306 4.17e-02 41_[+1(9.04e-05)]_31 chr3:20081509-20081589 2.57e-01 80 chr19:17416316-17416396 5.50e-02 24_[+3(7.75e-05)]_48 chr7:72848523-72848603 1.79e-01 80 chr16:21313040-21313120 2.53e-01 80 chr6:30569986-30570066 4.25e-02 80 chr14:23771378-23771458 1.58e-01 80 chr4:57843233-57843313 6.88e-02 80 chr5:141704185-141704265 5.86e-01 80 chr8:23082319-23082399 1.93e-01 80 chr2:176944745-176944825 3.46e-01 80 chr20:62328228-62328308 5.01e-01 80 chr9:34652164-34652244 8.55e-01 80 chr9:126031146-126031226 8.64e-01 80 chr9:124132117-124132197 2.58e-01 80 chr5:6633681-6633761 4.70e-01 80 chr2:136289413-136289493 1.68e-01 80 chr1:61519611-61519691 9.61e-01 80 chr5:149110312-149110392 4.55e-01 80 chr5:179248432-179248512 1.79e-01 80 chr1:6266531-6266611 8.36e-01 80 chr4:185394217-185394297 9.13e-01 80 chr1:54871071-54871151 1.48e-01 80 chr10:61666257-61666337 4.47e-01 80 -------------------------------------------------------------------------------- ******************************************************************************** ******************************************************************************** Stopped because requested number of motifs (5) found. ******************************************************************************** CPU: c22n04.farnam.hpc.yale.internal ********************************************************************************