******************************************************************************** MEME - Motif discovery tool ******************************************************************************** MEME version 5.3.3 (Release date: Sun Feb 7 15:39:52 2021 -0800) For further information on how to interpret these results please access https://meme-suite.org/meme. To get a copy of the MEME Suite software please access https://meme-suite.org. ******************************************************************************** ******************************************************************************** REFERENCE ******************************************************************************** If you use this program in your research, please cite: Timothy L. Bailey and Charles Elkan, "Fitting a mixture model by expectation maximization to discover motifs in biopolymers", Proceedings of the Second International Conference on Intelligent Systems for Molecular Biology, pp. 28-36, AAAI Press, Menlo Park, California, 1994. ******************************************************************************** ******************************************************************************** TRAINING SET ******************************************************************************** PRIMARY SEQUENCES= ../result/final_prediction/K562/fasta/RankLinear0.6_40/HMGN3.fasta CONTROL SEQUENCES= --none-- ALPHABET= ACGT Sequence name Weight Length Sequence name Weight Length ------------- ------ ------ ------------- ------ ------ chr19:1123179-1123259 1.0000 80 chr19:18854211-18854291 1.0000 80 chr5:139088897-139088977 1.0000 80 chr3:170074783-170074863 1.0000 80 chr22:22863039-22863119 1.0000 80 chr3:127795837-127795917 1.0000 80 chr17:76254789-76254869 1.0000 80 chr17:76142320-76142400 1.0000 80 chr1:59281045-59281125 1.0000 80 chr14:50470150-50470230 1.0000 80 chr17:42061336-42061416 1.0000 80 chr11:65189708-65189788 1.0000 80 chr14:65346684-65346764 1.0000 80 chr7:5614633-5614713 1.0000 80 chr16:8962284-8962364 1.0000 80 chr12:56523085-56523165 1.0000 80 chr2:64872361-64872441 1.0000 80 chr8:103666332-103666412 1.0000 80 chr16:85595026-85595106 1.0000 80 chr1:209848531-209848611 1.0000 80 chr12:53268096-53268176 1.0000 80 chr19:18268032-18268112 1.0000 80 chr1:59282074-59282154 1.0000 80 chrX:48644381-48644461 1.0000 80 chr18:77267158-77267238 1.0000 80 chr19:39894611-39894691 1.0000 80 chr2:8819006-8819086 1.0000 80 chr11:69827708-69827788 1.0000 80 chr9:139334394-139334474 1.0000 80 chr2:200320552-200320632 1.0000 80 chr5:133801616-133801696 1.0000 80 chr5:179248581-179248661 1.0000 80 chr12:8123378-8123458 1.0000 80 chr11:70588839-70588919 1.0000 80 chr5:141736683-141736763 1.0000 80 chr11:16626446-16626526 1.0000 80 chr19:10654371-10654451 1.0000 80 chr2:128165677-128165757 1.0000 80 chr19:4328505-4328585 1.0000 80 chr19:13961338-13961418 1.0000 80 chr14:75743875-75743955 1.0000 80 chr12:50561212-50561292 1.0000 80 chr5:131831606-131831686 1.0000 80 chr12:122235204-12223528 1.0000 80 chr1:43423898-43423978 1.0000 80 chr9:126122587-126122667 1.0000 80 chr19:13162620-13162700 1.0000 80 chr5:39424988-39425068 1.0000 80 chr1:2064732-2064812 1.0000 80 chr10:135059389-13505946 1.0000 80 chr9:94662458-94662538 1.0000 80 chr5:177540454-177540534 1.0000 80 chr16:87086950-87087030 1.0000 80 chr19:46272706-46272786 1.0000 80 chr17:76356338-76356418 1.0000 80 chr17:61819262-61819342 1.0000 80 chr19:14628770-14628850 1.0000 80 chr17:46570057-46570137 1.0000 80 chr14:104625352-10462543 1.0000 80 chr10:11653733-11653813 1.0000 80 chr19:1021114-1021194 1.0000 80 chr19:13273912-13273992 1.0000 80 chr10:65389906-65389986 1.0000 80 chr6:37070467-37070547 1.0000 80 chr19:2169118-2169198 1.0000 80 chr12:94136114-94136194 1.0000 80 chr6:32163596-32163676 1.0000 80 chr6:44044418-44044498 1.0000 80 chr11:3253183-3253263 1.0000 80 chr10:75670923-75671003 1.0000 80 chrX:154033788-154033868 1.0000 80 chr2:24713706-24713786 1.0000 80 chr20:57199085-57199165 1.0000 80 chr1:877274-877354 1.0000 80 chr3:5229284-5229364 1.0000 80 chrX:71238440-71238520 1.0000 80 chr2:17699743-17699823 1.0000 80 chr7:56131882-56131962 1.0000 80 chr1:41826827-41826907 1.0000 80 chr17:26903962-26904042 1.0000 80 chr2:74776092-74776172 1.0000 80 chr5:141392621-141392701 1.0000 80 chr11:34460176-34460256 1.0000 80 chr3:39195142-39195222 1.0000 80 chr19:11494986-11495066 1.0000 80 chr16:67198577-67198657 1.0000 80 chr14:74208346-74208426 1.0000 80 chr1:159894399-159894479 1.0000 80 chrX:40032064-40032144 1.0000 80 chr7:44187174-44187254 1.0000 80 chr12:4430108-4430188 1.0000 80 chr17:74732591-74732671 1.0000 80 chr16:88522378-88522458 1.0000 80 chr7:50237305-50237385 1.0000 80 chr1:223900143-223900223 1.0000 80 chr5:95066888-95066968 1.0000 80 chr16:89043497-89043577 1.0000 80 chr12:50067519-50067599 1.0000 80 chr8:99956557-99956637 1.0000 80 chr3:12994870-12994950 1.0000 80 chr5:53813493-53813573 1.0000 80 chr10:99447126-99447206 1.0000 80 chr2:220390723-220390803 1.0000 80 chr6:31870028-31870108 1.0000 80 chr1:23881344-23881424 1.0000 80 chr11:69064952-69065032 1.0000 80 chr8:21917525-21917605 1.0000 80 chr9:132250943-132251023 1.0000 80 chr5:176074459-176074539 1.0000 80 chr16:85587066-85587146 1.0000 80 chr3:193852861-193852941 1.0000 80 chr1:78225517-78225597 1.0000 80 chr16:31117191-31117271 1.0000 80 chr6:157041202-157041282 1.0000 80 chr10:72972221-72972301 1.0000 80 chr7:105752779-105752859 1.0000 80 chr18:3013346-3013426 1.0000 80 chr15:67095636-67095716 1.0000 80 chr9:98273320-98273400 1.0000 80 chr7:126987867-126987947 1.0000 80 chr19:14474518-14474598 1.0000 80 chr19:35531966-35532046 1.0000 80 chr16:50875139-50875219 1.0000 80 chr15:68177081-68177161 1.0000 80 chr17:49022053-49022133 1.0000 80 chr19:49137861-49137941 1.0000 80 chr3:50649373-50649453 1.0000 80 chr1:205718705-205718785 1.0000 80 chr21:44394428-44394508 1.0000 80 chr4:170541520-170541600 1.0000 80 chr17:40464461-40464541 1.0000 80 chr3:38066609-38066689 1.0000 80 chr4:39699580-39699660 1.0000 80 chr17:37823915-37823995 1.0000 80 chr7:5638634-5638714 1.0000 80 chr7:102036695-102036775 1.0000 80 chr7:1688046-1688126 1.0000 80 chr10:80733319-80733399 1.0000 80 chr7:120628743-120628823 1.0000 80 chr6:44214135-44214215 1.0000 80 chr11:2911984-2912064 1.0000 80 chr11:69264620-69264700 1.0000 80 chr6:12009288-12009368 1.0000 80 chr1:36235059-36235139 1.0000 80 chr14:74226940-74227020 1.0000 80 chr8:29940580-29940660 1.0000 80 chr1:222885451-222885531 1.0000 80 chr10:94831613-94831693 1.0000 80 chr7:12443256-12443336 1.0000 80 chr1:1850909-1850989 1.0000 80 chr6:52369040-52369120 1.0000 80 chr6:137113608-137113688 1.0000 80 chr15:66923411-66923491 1.0000 80 chr2:172963864-172963944 1.0000 80 chr17:27503817-27503897 1.0000 80 chr6:134496152-134496232 1.0000 80 chr11:65341825-65341905 1.0000 80 chr2:43454589-43454669 1.0000 80 chr19:41129936-41130016 1.0000 80 chr7:73153363-73153443 1.0000 80 chr6:34530773-34530853 1.0000 80 chr1:27895063-27895143 1.0000 80 chr11:69794804-69794884 1.0000 80 chr2:176866990-176867070 1.0000 80 chr6:43737858-43737938 1.0000 80 chr1:243418332-243418412 1.0000 80 chr20:32319832-32319912 1.0000 80 chr1:999719-999799 1.0000 80 chr1:54954038-54954118 1.0000 80 chr1:23884932-23885012 1.0000 80 chr3:196359459-196359539 1.0000 80 chr1:228528802-228528882 1.0000 80 chr19:13030131-13030211 1.0000 80 chr16:85411449-85411529 1.0000 80 chr17:40172057-40172137 1.0000 80 chr19:34818893-34818973 1.0000 80 chr12:69139874-69139954 1.0000 80 chr11:2800020-2800100 1.0000 80 chr20:43589076-43589156 1.0000 80 chr1:150980868-150980948 1.0000 80 chr3:193721011-193721091 1.0000 80 chr9:93956102-93956182 1.0000 80 chr11:64072823-64072903 1.0000 80 chr22:19279157-19279237 1.0000 80 chrX:39874247-39874327 1.0000 80 chr6:10838751-10838831 1.0000 80 chr2:74730437-74730517 1.0000 80 chr16:69599767-69599847 1.0000 80 chr7:5569510-5569590 1.0000 80 chr5:96270861-96270941 1.0000 80 chr19:48825324-48825404 1.0000 80 chr19:46919777-46919857 1.0000 80 chr9:114937579-114937659 1.0000 80 chr1:16212950-16213030 1.0000 80 chr4:1787006-1787086 1.0000 80 chr19:40927247-40927327 1.0000 80 chr22:19946883-19946963 1.0000 80 chr19:907343-907423 1.0000 80 chr1:16162402-16162482 1.0000 80 chr9:96328829-96328909 1.0000 80 chr10:6205780-6205860 1.0000 80 chr9:116163626-116163706 1.0000 80 chr1:12678362-12678442 1.0000 80 chr19:15947594-15947674 1.0000 80 chr6:33378154-33378234 1.0000 80 chr6:30710609-30710689 1.0000 80 chr20:60697194-60697274 1.0000 80 chr7:105925665-105925745 1.0000 80 chr6:108880490-108880570 1.0000 80 chr6:44187224-44187304 1.0000 80 chr12:27167347-27167427 1.0000 80 chr16:85647042-85647122 1.0000 80 chr19:40949245-40949325 1.0000 80 chr13:52377826-52377906 1.0000 80 chr19:944255-944335 1.0000 80 chr12:52430781-52430861 1.0000 80 chr19:16369403-16369483 1.0000 80 chr1:154973535-154973615 1.0000 80 chr8:41655166-41655246 1.0000 80 chr2:11886766-11886846 1.0000 80 chr17:35085084-35085164 1.0000 80 chr12:111806876-11180695 1.0000 80 chr7:5594672-5594752 1.0000 80 chr11:64655462-64655542 1.0000 80 chr19:54372751-54372831 1.0000 80 chr7:128095818-128095898 1.0000 80 chr3:193859517-193859597 1.0000 80 chr19:52207364-52207444 1.0000 80 chr19:9186380-9186460 1.0000 80 chr12:46765168-46765248 1.0000 80 chr15:66914595-66914675 1.0000 80 chr1:43871053-43871133 1.0000 80 chr1:213031555-213031635 1.0000 80 chr1:45075946-45076026 1.0000 80 chr6:159240405-159240485 1.0000 80 chr19:13210299-13210379 1.0000 80 chr1:33647636-33647716 1.0000 80 chr4:122632855-122632935 1.0000 80 chr20:30263439-30263519 1.0000 80 chr11:61517289-61517369 1.0000 80 chr7:73130257-73130337 1.0000 80 chr3:47021144-47021224 1.0000 80 chr16:30825699-30825779 1.0000 80 chrX:153193708-153193788 1.0000 80 chr11:118505628-11850570 1.0000 80 chr7:23513947-23514027 1.0000 80 chr18:12407781-12407861 1.0000 80 chr5:90576457-90576537 1.0000 80 chr11:63775418-63775498 1.0000 80 chr3:141765325-141765405 1.0000 80 ******************************************************************************** ******************************************************************************** COMMAND LINE SUMMARY ******************************************************************************** This information can also be useful in the event you wish to report a problem with the MEME software. command: meme -oc ../result/final_prediction/K562/inference_raw/MEME/RankLinear0.6_40_HMGN3/ -dna -nmotifs 5 -w 8 -maxsize 250000 -nostatus ../result/final_prediction/K562/fasta/RankLinear0.6_40/HMGN3.fasta model: mod= zoops nmotifs= 5 evt= inf objective function: em= E-value of product of p-values starts= E-value of product of p-values strands: + width: minw= 8 maxw= 8 nsites: minsites= 2 maxsites= 250 wnsites= 0.8 theta: spmap= uni spfuzz= 0.5 em: prior= dirichlet b= 0.01 maxiter= 50 distance= 1e-05 trim: wg= 11 ws= 1 endgaps= yes data: n= 20000 N= 250 sample: seed= 0 hsfrac= 0 searchsize= 20000 norand= no csites= 1000 Letter frequencies in dataset: A 0.133 C 0.373 G 0.36 T 0.133 Background letter frequencies (from file dataset with add-one prior applied): A 0.133 C 0.373 G 0.36 T 0.133 Background model order: 0 ******************************************************************************** ******************************************************************************** MOTIF TGASTCAC MEME-1 width = 8 sites = 22 llr = 229 E-value = 2.5e-012 ******************************************************************************** -------------------------------------------------------------------------------- Motif TGASTCAC MEME-1 Description -------------------------------------------------------------------------------- Simplified A ::a:::a: pos.-specific C :::4:a:6 probability G :a:5:::1 matrix T a:::a::2 bits 2.9 * * * 2.6 * * * * 2.3 * * * * 2.0 * * * * Relative 1.7 * * * * Entropy 1.5 *** *** (15.0 bits) 1.2 *** *** 0.9 *** *** 0.6 *** **** 0.3 ******** 0.0 -------- Multilevel TGAGTCAC consensus C T sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGASTCAC MEME-1 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr1:154973535-154973615 48 7.65e-06 GCCCCGAGGC TGAGTCAC GGCCCGGCGC chr2:172963864-172963944 60 7.65e-06 CCGCGCTGAG TGAGTCAC CCCGCCGCCG chr11:69264620-69264700 15 7.65e-06 TGCCCGGGCA TGAGTCAT GGGCCAGCCC chr9:132250943-132251023 15 7.65e-06 CTCGGGGCCC TGAGTCAT CGCCGCCCCC chr7:50237305-50237385 24 7.65e-06 GCCTCAGGGA TGAGTCAT GCCGCCAGGC chr1:159894399-159894479 29 7.65e-06 TTACAACAGA TGAGTCAC CCACCGCCCT chrX:71238440-71238520 58 7.65e-06 GCCGGCGCGA TGAGTCAC CATCCCTCAG chr20:57199085-57199165 11 7.65e-06 GTGTCTGGAG TGAGTCAC TGGCTGAGCC chr5:133801616-133801696 56 7.65e-06 CGGCGGGAGC TGAGTCAC GGCGGCCCTG chr19:39894611-39894691 15 7.65e-06 CCCTTGCGAG TGAGTCAC GGGCGAGCAG chr19:9186380-9186460 57 1.56e-05 CCACTGCCCA TGACTCAC TCGGCCCCCC chr1:999719-999799 49 1.56e-05 ACGCACATCA TGACTCAC TCCCAGGTGG chr11:69794804-69794884 29 1.56e-05 TCTGCGAGGC TGACTCAC GGTGGAGGGA chr14:74208346-74208426 72 1.56e-05 CCCGCCTGCG TGACTCAC T chr19:13961338-13961418 55 1.56e-05 cggcgcgcgg TGACTCAC CGCGGCGTGA chr2:128165677-128165757 25 1.56e-05 CAGGGGGCGC TGACTCAC AGGCTGACTC chr12:53268096-53268176 56 1.56e-05 cgcTCCGCGG TGACTCAT CCAGCACCCC chr1:223900143-223900223 68 2.39e-05 TTCCCTCCGG TGAATCAT CGCTC chr5:177540454-177540534 66 2.39e-05 CGCGCGCCGG TGAGTCAG GCCGGGT chr4:122632855-122632935 69 2.95e-05 GGTCCGCGGG TGACTCAG CGTC chr5:141392621-141392701 43 2.95e-05 cccgccgggc TGACTCAG CTTGGCCGCA chr1:243418332-243418412 64 3.92e-05 TCGCGTCCCG TGAGTCTC TCGCACGCC -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGASTCAC MEME-1 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr1:154973535-154973615 7.7e-06 47_[+1]_25 chr2:172963864-172963944 7.7e-06 59_[+1]_13 chr11:69264620-69264700 7.7e-06 14_[+1]_58 chr9:132250943-132251023 7.7e-06 14_[+1]_58 chr7:50237305-50237385 7.7e-06 23_[+1]_49 chr1:159894399-159894479 7.7e-06 28_[+1]_44 chrX:71238440-71238520 7.7e-06 57_[+1]_15 chr20:57199085-57199165 7.7e-06 10_[+1]_62 chr5:133801616-133801696 7.7e-06 55_[+1]_17 chr19:39894611-39894691 7.7e-06 14_[+1]_58 chr19:9186380-9186460 1.6e-05 56_[+1]_16 chr1:999719-999799 1.6e-05 48_[+1]_24 chr11:69794804-69794884 1.6e-05 28_[+1]_44 chr14:74208346-74208426 1.6e-05 71_[+1]_1 chr19:13961338-13961418 1.6e-05 54_[+1]_18 chr2:128165677-128165757 1.6e-05 24_[+1]_48 chr12:53268096-53268176 1.6e-05 55_[+1]_17 chr1:223900143-223900223 2.4e-05 67_[+1]_5 chr5:177540454-177540534 2.4e-05 65_[+1]_7 chr4:122632855-122632935 2.9e-05 68_[+1]_4 chr5:141392621-141392701 2.9e-05 42_[+1]_30 chr1:243418332-243418412 3.9e-05 63_[+1]_9 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGASTCAC MEME-1 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF TGASTCAC width=8 seqs=22 chr1:154973535-154973615 ( 48) TGAGTCAC 1 chr2:172963864-172963944 ( 60) TGAGTCAC 1 chr11:69264620-69264700 ( 15) TGAGTCAT 1 chr9:132250943-132251023 ( 15) TGAGTCAT 1 chr7:50237305-50237385 ( 24) TGAGTCAT 1 chr1:159894399-159894479 ( 29) TGAGTCAC 1 chrX:71238440-71238520 ( 58) TGAGTCAC 1 chr20:57199085-57199165 ( 11) TGAGTCAC 1 chr5:133801616-133801696 ( 56) TGAGTCAC 1 chr19:39894611-39894691 ( 15) TGAGTCAC 1 chr19:9186380-9186460 ( 57) TGACTCAC 1 chr1:999719-999799 ( 49) TGACTCAC 1 chr11:69794804-69794884 ( 29) TGACTCAC 1 chr14:74208346-74208426 ( 72) TGACTCAC 1 chr19:13961338-13961418 ( 55) TGACTCAC 1 chr2:128165677-128165757 ( 25) TGACTCAC 1 chr12:53268096-53268176 ( 56) TGACTCAT 1 chr1:223900143-223900223 ( 68) TGAATCAT 1 chr5:177540454-177540534 ( 66) TGAGTCAG 1 chr4:122632855-122632935 ( 69) TGACTCAG 1 chr5:141392621-141392701 ( 43) TGACTCAG 1 chr1:243418332-243418412 ( 64) TGAGTCTC 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGASTCAC MEME-1 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 10.0499 E= 2.5e-012 -1110 -1110 -1110 291 -1110 -1110 147 -1110 291 -1110 -1110 -1110 -155 13 60 -1110 -1110 -1110 -1110 291 -1110 142 -1110 -1110 284 -1110 -1110 -155 -1110 77 -140 77 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGASTCAC MEME-1 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 22 E= 2.5e-012 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.045455 0.409091 0.545455 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 0.954545 0.000000 0.000000 0.045455 0.000000 0.636364 0.136364 0.227273 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGASTCAC MEME-1 regular expression -------------------------------------------------------------------------------- TGA[GC]TCA[CT] -------------------------------------------------------------------------------- Time 4.92 secs. ******************************************************************************** ******************************************************************************** MOTIF SAGATAAG MEME-2 width = 8 sites = 22 llr = 212 E-value = 1.0e-005 ******************************************************************************** -------------------------------------------------------------------------------- Motif SAGATAAG MEME-2 Description -------------------------------------------------------------------------------- Simplified A 16:a:9a: pos.-specific C 51::1::1 probability G 5:a::1:9 matrix T :3::9::: bits 2.9 * 2.6 * * 2.3 * ** 2.0 **** Relative 1.7 **** Entropy 1.5 ****** (13.9 bits) 1.2 ****** 0.9 ******* 0.6 ******* 0.3 ******** 0.0 -------- Multilevel CAGATAAG consensus GT sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif SAGATAAG MEME-2 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chrX:39874247-39874327 25 1.94e-06 TGACTCGGCC GAGATAAG GGTGCGCGGT chr11:70588839-70588919 23 1.94e-06 CTGGCTGCCG GAGATAAG AGGCAAGGGG chr6:34530773-34530853 64 3.95e-06 ACCGCAGGCC CAGATAAG AGCACAATC chr11:69264620-69264700 73 3.95e-06 CCGTTTCCTG CAGATAAG chr16:50875139-50875219 39 3.95e-06 gcggggcgcg cAGATAAG GTCTGGGGGC chr12:94136114-94136194 22 3.95e-06 GTGGGAGCTG CAGATAAG CCAGCGCTTg chr9:126122587-126122667 46 4.67e-06 GGGATTTGTA AAGATAAG CACAGGCCCC chr19:10654371-10654451 62 6.61e-06 TCCTGGCGGT GTGATAAG GAGGGCGGGG chr4:1787006-1787086 50 8.62e-06 CCTGGCTGGC CTGATAAG CTGCCCCTTT chr3:141765325-141765405 38 9.34e-06 TACAGAGGTA ATGATAAG AGAGATGGGA chr16:88522378-88522458 9 2.03e-05 CGCCAAGA GCGATAAG AGGCCTTATC chrX:40032064-40032144 50 2.03e-05 CTGACACTGG GCGATAAG GAGTTCCTCG chr3:12994870-12994950 38 2.63e-05 CTGCTGAGGC CCGATAAG GCCCGGCCCA chr16:89043497-89043577 14 2.70e-05 CTGTGTCCCC GTGATAAT GCCGGGGCCG chr2:176866990-176867070 1 3.32e-05 . GAGACAAG CCGGGCCAAC chr1:213031555-213031635 26 3.95e-05 GGGGCGGGAC CAGACAAG GGGTGACTGC chr2:74730437-74730517 22 3.95e-05 CCGCTGCTGA CAGACAAG ACCAAGGCTC chr11:34460176-34460256 20 4.56e-05 CTGAAGGATG CTGATAAC CGGGAGCCCC chr10:135059389-13505946 46 4.56e-05 GAGGCAGCCC CTGATAAC CGGCCTGGGG chr5:39424988-39425068 57 4.56e-05 CTCCCGGCGA GAGATATG GTTCTAATCA chr4:122632855-122632935 24 5.49e-05 CAGAGCCCAG GAGATGAG TAAGCGGCAG chr12:69139874-69139954 51 5.49e-05 GCTGCGGGCG GAGATGAG CGGGGCGTGG -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif SAGATAAG MEME-2 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chrX:39874247-39874327 1.9e-06 24_[+2]_48 chr11:70588839-70588919 1.9e-06 22_[+2]_50 chr6:34530773-34530853 4e-06 63_[+2]_9 chr11:69264620-69264700 4e-06 72_[+2] chr16:50875139-50875219 4e-06 38_[+2]_34 chr12:94136114-94136194 4e-06 21_[+2]_51 chr9:126122587-126122667 4.7e-06 45_[+2]_27 chr19:10654371-10654451 6.6e-06 61_[+2]_11 chr4:1787006-1787086 8.6e-06 49_[+2]_23 chr3:141765325-141765405 9.3e-06 37_[+2]_35 chr16:88522378-88522458 2e-05 8_[+2]_64 chrX:40032064-40032144 2e-05 49_[+2]_23 chr3:12994870-12994950 2.6e-05 37_[+2]_35 chr16:89043497-89043577 2.7e-05 13_[+2]_59 chr2:176866990-176867070 3.3e-05 [+2]_72 chr1:213031555-213031635 4e-05 25_[+2]_47 chr2:74730437-74730517 4e-05 21_[+2]_51 chr11:34460176-34460256 4.6e-05 19_[+2]_53 chr10:135059389-13505946 4.6e-05 45_[+2]_27 chr5:39424988-39425068 4.6e-05 56_[+2]_16 chr4:122632855-122632935 5.5e-05 23_[+2]_49 chr12:69139874-69139954 5.5e-05 50_[+2]_22 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif SAGATAAG MEME-2 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF SAGATAAG width=8 seqs=22 chrX:39874247-39874327 ( 25) GAGATAAG 1 chr11:70588839-70588919 ( 23) GAGATAAG 1 chr6:34530773-34530853 ( 64) CAGATAAG 1 chr11:69264620-69264700 ( 73) CAGATAAG 1 chr16:50875139-50875219 ( 39) CAGATAAG 1 chr12:94136114-94136194 ( 22) CAGATAAG 1 chr9:126122587-126122667 ( 46) AAGATAAG 1 chr19:10654371-10654451 ( 62) GTGATAAG 1 chr4:1787006-1787086 ( 50) CTGATAAG 1 chr3:141765325-141765405 ( 38) ATGATAAG 1 chr16:88522378-88522458 ( 9) GCGATAAG 1 chrX:40032064-40032144 ( 50) GCGATAAG 1 chr3:12994870-12994950 ( 38) CCGATAAG 1 chr16:89043497-89043577 ( 14) GTGATAAT 1 chr2:176866990-176867070 ( 1) GAGACAAG 1 chr1:213031555-213031635 ( 26) CAGACAAG 1 chr2:74730437-74730517 ( 22) CAGACAAG 1 chr11:34460176-34460256 ( 20) CTGATAAC 1 chr10:135059389-13505946 ( 46) CTGATAAC 1 chr5:39424988-39425068 ( 57) GAGATATG 1 chr4:122632855-122632935 ( 24) GAGATGAG 1 chr12:69139874-69139954 ( 51) GAGATGAG 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif SAGATAAG MEME-2 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 10.7218 E= 1.0e-005 -55 28 34 -1110 215 -145 -1110 103 -1110 -1110 147 -1110 291 -1110 -1110 -1110 -1110 -145 -1110 269 277 -1110 -198 -1110 284 -1110 -1110 -155 -1110 -204 126 -155 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif SAGATAAG MEME-2 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 22 E= 1.0e-005 0.090909 0.454545 0.454545 0.000000 0.590909 0.136364 0.000000 0.272727 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.136364 0.000000 0.863636 0.909091 0.000000 0.090909 0.000000 0.954545 0.000000 0.000000 0.045455 0.000000 0.090909 0.863636 0.045455 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif SAGATAAG MEME-2 regular expression -------------------------------------------------------------------------------- [CG][AT]GATAAG -------------------------------------------------------------------------------- Time 8.54 secs. ******************************************************************************** ******************************************************************************** MOTIF TTATCTGC MEME-3 width = 8 sites = 27 llr = 243 E-value = 1.4e-004 ******************************************************************************** -------------------------------------------------------------------------------- Motif TTATCTGC MEME-3 Description -------------------------------------------------------------------------------- Simplified A 11a::1:1 pos.-specific C :1::9:36 probability G :::1::61 matrix T 97:91912 bits 2.9 * 2.6 * 2.3 * ** * 2.0 * ** * Relative 1.7 * ** * Entropy 1.5 **** * (13.0 bits) 1.2 ****** 0.9 ****** 0.6 ****** 0.3 ******** 0.0 -------- Multilevel TTATCTGC consensus C sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTATCTGC MEME-3 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr15:66914595-66914675 45 2.08e-06 GCCCTGGGCG TTATCTGC GCTAGCCCGG chr19:9186380-9186460 12 2.08e-06 CCGAGGGTAA TTATCTGC ACCCAGCCAT chr19:35531966-35532046 3 2.08e-06 TG TTATCTGC CTGCGGACGC chrX:48644381-48644461 2 2.08e-06 C TTATCTGC TGCCCCAGGG chr19:944255-944335 14 5.73e-06 TGTCTCGCCG TTATCTCC CAGGCGTGTC chr2:220390723-220390803 25 5.73e-06 TGGCTGCTTC TTATCTCC TGGAGGCCCA chr17:42061336-42061416 8 5.73e-06 CGCGCGC TTATCTCC CGCAAACACC chr17:76142320-76142400 54 5.73e-06 GGCCTCCAGG TTATCTCC CCACTGCAGG chr16:88522378-88522458 22 8.55e-06 ATAAGAGGCC TTATCTTT GGCCACCAGG chr11:16626446-16626526 41 1.14e-05 GGCACCGAGC TAATCTGC CCTCAGCAGC chr11:69794804-69794884 16 1.66e-05 AGGCCTCCTG ATATCTGC GAGGCTGACT chr1:45075946-45076026 9 1.91e-05 TTTCCTCG TTATCAGT GCAAGGGCTG chr1:43871053-43871133 68 1.91e-05 TGTTACTGGA ATATCTGT TTATG chr16:85595026-85595106 7 2.17e-05 AGCCCC TTATCTGG TTCCTGTCGT chr1:213031555-213031635 68 4.62e-05 GAGGAGACCT TCATCTGT TCACG chr18:77267158-77267238 53 4.62e-05 CCAGCTGCTG TTATTTTA GATATGGCAG chr17:74732591-74732671 40 4.88e-05 caggccgccA TTATCTCG CCGCCAGACG chr2:17699743-17699823 55 5.01e-05 GGCCTTAGCC TAATCTCA GGGTTTgccc chr3:193721011-193721091 44 5.96e-05 CCCGAGATCC TTAACTGC AGCTTCCAAA chr16:87086950-87087030 42 5.96e-05 TCGCCTGCTG AAATCTGC AAGCTCATCA chr6:10838751-10838831 25 7.37e-05 CTTGTGTGTT TCATCTCC TAGGAAACGG chr14:50470150-50470230 70 7.37e-05 cagcggccgg ATATCAGC TGC chr6:37070467-37070547 10 8.89e-05 GACGCCGCG TCATTTGC ATGGCAACCT chr5:39424988-39425068 69 1.03e-04 GATATGGTTC TAATCAGA TGCT chr14:74226940-74227020 57 1.43e-04 CTCTACCACT TCATCAGC ACAACTGTCT chrX:40032064-40032144 18 1.43e-04 AGGCGGACGT TTAGCTCC GGCACCCGGG chr16:30825699-30825779 3 1.81e-04 TC TTAGTTGT CTGGGCCGCT -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTATCTGC MEME-3 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr15:66914595-66914675 2.1e-06 44_[+3]_28 chr19:9186380-9186460 2.1e-06 11_[+3]_61 chr19:35531966-35532046 2.1e-06 2_[+3]_70 chrX:48644381-48644461 2.1e-06 1_[+3]_71 chr19:944255-944335 5.7e-06 13_[+3]_59 chr2:220390723-220390803 5.7e-06 24_[+3]_48 chr17:42061336-42061416 5.7e-06 7_[+3]_65 chr17:76142320-76142400 5.7e-06 53_[+3]_19 chr16:88522378-88522458 8.6e-06 21_[+3]_51 chr11:16626446-16626526 1.1e-05 40_[+3]_32 chr11:69794804-69794884 1.7e-05 15_[+3]_57 chr1:45075946-45076026 1.9e-05 8_[+3]_64 chr1:43871053-43871133 1.9e-05 67_[+3]_5 chr16:85595026-85595106 2.2e-05 6_[+3]_66 chr1:213031555-213031635 4.6e-05 67_[+3]_5 chr18:77267158-77267238 4.6e-05 52_[+3]_20 chr17:74732591-74732671 4.9e-05 39_[+3]_33 chr2:17699743-17699823 5e-05 54_[+3]_18 chr3:193721011-193721091 6e-05 43_[+3]_29 chr16:87086950-87087030 6e-05 41_[+3]_31 chr6:10838751-10838831 7.4e-05 24_[+3]_48 chr14:50470150-50470230 7.4e-05 69_[+3]_3 chr6:37070467-37070547 8.9e-05 9_[+3]_63 chr5:39424988-39425068 0.0001 68_[+3]_4 chr14:74226940-74227020 0.00014 56_[+3]_16 chrX:40032064-40032144 0.00014 17_[+3]_55 chr16:30825699-30825779 0.00018 2_[+3]_70 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTATCTGC MEME-3 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF TTATCTGC width=8 seqs=27 chr15:66914595-66914675 ( 45) TTATCTGC 1 chr19:9186380-9186460 ( 12) TTATCTGC 1 chr19:35531966-35532046 ( 3) TTATCTGC 1 chrX:48644381-48644461 ( 2) TTATCTGC 1 chr19:944255-944335 ( 14) TTATCTCC 1 chr2:220390723-220390803 ( 25) TTATCTCC 1 chr17:42061336-42061416 ( 8) TTATCTCC 1 chr17:76142320-76142400 ( 54) TTATCTCC 1 chr16:88522378-88522458 ( 22) TTATCTTT 1 chr11:16626446-16626526 ( 41) TAATCTGC 1 chr11:69794804-69794884 ( 16) ATATCTGC 1 chr1:45075946-45076026 ( 9) TTATCAGT 1 chr1:43871053-43871133 ( 68) ATATCTGT 1 chr16:85595026-85595106 ( 7) TTATCTGG 1 chr1:213031555-213031635 ( 68) TCATCTGT 1 chr18:77267158-77267238 ( 53) TTATTTTA 1 chr17:74732591-74732671 ( 40) TTATCTCG 1 chr2:17699743-17699823 ( 55) TAATCTCA 1 chr3:193721011-193721091 ( 44) TTAACTGC 1 chr16:87086950-87087030 ( 42) AAATCTGC 1 chr6:10838751-10838831 ( 25) TCATCTCC 1 chr14:50470150-50470230 ( 70) ATATCAGC 1 chr6:37070467-37070547 ( 10) TCATTTGC 1 chr5:39424988-39425068 ( 69) TAATCAGA 1 chr14:74226940-74227020 ( 57) TCATCAGC 1 chrX:40032064-40032144 ( 18) TTAGCTCC 1 chr16:30825699-30825779 ( 3) TTAGTTGT 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTATCTGC MEME-3 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 9.9683 E= 1.4e-004 15 -1140 -1140 267 15 -133 -1140 240 291 -1140 -1140 -1140 -185 -1140 -228 274 -1140 125 -1140 -26 15 -1140 -1140 267 -1140 -33 81 -85 -26 75 -228 47 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTATCTGC MEME-3 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 27 E= 1.4e-004 0.148148 0.000000 0.000000 0.851852 0.148148 0.148148 0.000000 0.703704 1.000000 0.000000 0.000000 0.000000 0.037037 0.000000 0.074074 0.888889 0.000000 0.888889 0.000000 0.111111 0.148148 0.000000 0.000000 0.851852 0.000000 0.296296 0.629630 0.074074 0.111111 0.629630 0.074074 0.185185 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTATCTGC MEME-3 regular expression -------------------------------------------------------------------------------- TTATCT[GC]C -------------------------------------------------------------------------------- Time 12.18 secs. ******************************************************************************** ******************************************************************************** MOTIF TRTKTTTW MEME-4 width = 8 sites = 9 llr = 102 E-value = 7.5e+000 ******************************************************************************** -------------------------------------------------------------------------------- Motif TRTKTTTW MEME-4 Description -------------------------------------------------------------------------------- Simplified A :3::1::6 pos.-specific C :::::::1 probability G :6:4:2:: matrix T a1a698a3 bits 2.9 * * * 2.6 * * * 2.3 * * * * 2.0 * * * * Relative 1.7 * * *** Entropy 1.5 * * **** (16.4 bits) 1.2 * ****** 0.9 ******** 0.6 ******** 0.3 ******** 0.0 -------- Multilevel TGTTTTTA consensus A G G T sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TRTKTTTW MEME-4 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr18:12407781-12407861 39 9.79e-08 CCCGCAGAGC TATTTTTA GCCGCTGCAG chr12:52430781-52430861 44 9.79e-08 CGGGCGCCGC TATTTTTA GCCCCATTGA chr6:43737858-43737938 56 1.09e-06 CCCCCCCTTT TTTTTTTA AAAGTCGGCT chr7:120628743-120628823 59 2.17e-06 CGCGCGCGCg tgtgttta tgtgtctgtg chr19:35531966-35532046 57 2.98e-06 CCCTTAGCGC TGTGTTTT CCCGGCCAAG chr3:193859517-193859597 29 6.41e-06 cgccTGCCAG TGTTTTTC CAGTTCCCCC chr19:13961338-13961418 14 7.12e-06 AGCAACGCGC TGTTTGTT ggcgcggggg chr14:104625352-10462543 37 7.49e-06 TGACGGGGCA TATGATTA GGGCATTGTC chr6:10838751-10838831 17 1.84e-05 TCCGGCGTCT TGTGTGTT TCATCTCCTA -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TRTKTTTW MEME-4 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr18:12407781-12407861 9.8e-08 38_[+4]_34 chr12:52430781-52430861 9.8e-08 43_[+4]_29 chr6:43737858-43737938 1.1e-06 55_[+4]_17 chr7:120628743-120628823 2.2e-06 58_[+4]_14 chr19:35531966-35532046 3e-06 56_[+4]_16 chr3:193859517-193859597 6.4e-06 28_[+4]_44 chr19:13961338-13961418 7.1e-06 13_[+4]_59 chr14:104625352-10462543 7.5e-06 36_[+4]_36 chr6:10838751-10838831 1.8e-05 16_[+4]_56 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TRTKTTTW MEME-4 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF TRTKTTTW width=8 seqs=9 chr18:12407781-12407861 ( 39) TATTTTTA 1 chr12:52430781-52430861 ( 44) TATTTTTA 1 chr6:43737858-43737938 ( 56) TTTTTTTA 1 chr7:120628743-120628823 ( 59) TGTGTTTA 1 chr19:35531966-35532046 ( 57) TGTGTTTT 1 chr3:193859517-193859597 ( 29) TGTTTTTC 1 chr19:13961338-13961418 ( 14) TGTTTGTT 1 chr14:104625352-10462543 ( 37) TATGATTA 1 chr6:10838751-10838831 ( 17) TGTGTGTT 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TRTKTTTW MEME-4 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 12.3898 E= 7.5e+000 -982 -982 -982 290 132 -982 63 -26 -982 -982 -982 290 -982 -982 30 206 -26 -982 -982 273 -982 -982 -69 254 -982 -982 -982 290 206 -174 -982 132 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TRTKTTTW MEME-4 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 9 E= 7.5e+000 0.000000 0.000000 0.000000 1.000000 0.333333 0.000000 0.555556 0.111111 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.444444 0.555556 0.111111 0.000000 0.000000 0.888889 0.000000 0.000000 0.222222 0.777778 0.000000 0.000000 0.000000 1.000000 0.555556 0.111111 0.000000 0.333333 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TRTKTTTW MEME-4 regular expression -------------------------------------------------------------------------------- T[GA]T[TG]T[TG]T[AT] -------------------------------------------------------------------------------- Time 15.76 secs. ******************************************************************************** ******************************************************************************** MOTIF KTAAACAD MEME-5 width = 8 sites = 6 llr = 69 E-value = 5.4e+003 ******************************************************************************** -------------------------------------------------------------------------------- Motif KTAAACAD MEME-5 Description -------------------------------------------------------------------------------- Simplified A :2aaa:a3 pos.-specific C :::::7:: probability G 3::::2:3 matrix T 78:::2:3 bits 2.9 *** * 2.6 *** * 2.3 **** * 2.0 **** * Relative 1.7 **** * Entropy 1.5 ***** * (16.7 bits) 1.2 ***** * 0.9 ***** ** 0.6 ***** ** 0.3 ******** 0.0 -------- Multilevel TTAAACAA consensus G G sequence T -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif KTAAACAD MEME-5 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr5:141736683-141736763 16 5.49e-07 TAAATTTCCT TTAAACAT CCCCACCGCG chr5:39424988-39425068 6 2.28e-06 CTCGC TTAAATAG CCGCCGGCCG chr19:13162620-13162700 1 2.28e-06 . TTAAAGAA ACACAACCCG chr3:193852861-193852941 34 2.83e-06 gcggcggcAA TAAAACAT CCTGGCACGT chr5:179248581-179248661 36 4.32e-06 AGTGACGCGG GTAAACAA GCGCGGGGGT chr14:75743875-75743955 59 8.52e-06 CTGTGTTGCT GTAAACAG CCGCTTCCCT -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif KTAAACAD MEME-5 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr5:141736683-141736763 5.5e-07 15_[+5]_57 chr5:39424988-39425068 2.3e-06 5_[+5]_67 chr19:13162620-13162700 2.3e-06 [+5]_72 chr3:193852861-193852941 2.8e-06 33_[+5]_39 chr5:179248581-179248661 4.3e-06 35_[+5]_37 chr14:75743875-75743955 8.5e-06 58_[+5]_14 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif KTAAACAD MEME-5 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF KTAAACAD width=8 seqs=6 chr5:141736683-141736763 ( 16) TTAAACAT 1 chr5:39424988-39425068 ( 6) TTAAATAG 1 chr19:13162620-13162700 ( 1) TTAAAGAA 1 chr3:193852861-193852941 ( 34) TAAAACAT 1 chr5:179248581-179248661 ( 36) GTAAACAA 1 chr14:75743875-75743955 ( 59) GTAAACAG 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif KTAAACAD MEME-5 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 12.67 E= 5.4e+003 -923 -923 -11 232 32 -923 -923 264 290 -923 -923 -923 290 -923 -923 -923 290 -923 -923 -923 -923 84 -111 32 290 -923 -923 -923 132 -923 -11 132 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif KTAAACAD MEME-5 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 6 E= 5.4e+003 0.000000 0.000000 0.333333 0.666667 0.166667 0.000000 0.000000 0.833333 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.666667 0.166667 0.166667 1.000000 0.000000 0.000000 0.000000 0.333333 0.000000 0.333333 0.333333 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif KTAAACAD MEME-5 regular expression -------------------------------------------------------------------------------- [TG]TAAACA[AGT] -------------------------------------------------------------------------------- Time 19.33 secs. ******************************************************************************** ******************************************************************************** SUMMARY OF MOTIFS ******************************************************************************** -------------------------------------------------------------------------------- Combined block diagrams: non-overlapping sites with p-value < 0.0001 -------------------------------------------------------------------------------- SEQUENCE NAME COMBINED P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr19:1123179-1123259 8.79e-01 80 chr19:18854211-18854291 2.21e-01 80 chr5:139088897-139088977 1.68e-01 80 chr3:170074783-170074863 9.29e-01 80 chr22:22863039-22863119 9.82e-01 80 chr3:127795837-127795917 9.35e-01 80 chr17:76254789-76254869 7.85e-01 80 chr17:76142320-76142400 2.18e-02 53_[+3(5.73e-06)]_19 chr1:59281045-59281125 9.92e-01 80 chr14:50470150-50470230 4.27e-02 69_[+3(7.37e-05)]_3 chr17:42061336-42061416 5.63e-03 7_[+3(5.73e-06)]_65 chr11:65189708-65189788 2.28e-01 80 chr14:65346684-65346764 5.47e-01 80 chr7:5614633-5614713 4.94e-01 80 chr16:8962284-8962364 7.70e-01 80 chr12:56523085-56523165 9.99e-01 80 chr2:64872361-64872441 8.60e-01 80 chr8:103666332-103666412 1.26e-02 80 chr16:85595026-85595106 2.71e-03 6_[+3(2.17e-05)]_66 chr1:209848531-209848611 3.45e-01 80 chr12:53268096-53268176 6.54e-02 55_[+1(1.56e-05)]_17 chr19:18268032-18268112 6.59e-01 80 chr1:59282074-59282154 8.33e-01 80 chrX:48644381-48644461 5.23e-04 1_[+3(2.08e-06)]_71 chr18:77267158-77267238 3.80e-06 50_[+4(6.41e-06)]_22 chr19:39894611-39894691 1.32e-02 14_[+1(7.65e-06)]_58 chr2:8819006-8819086 4.66e-01 80 chr11:69827708-69827788 1.66e-01 80 chr9:139334394-139334474 9.57e-01 80 chr2:200320552-200320632 6.35e-01 80 chr5:133801616-133801696 3.24e-02 55_[+1(7.65e-06)]_17 chr5:179248581-179248661 1.30e-02 35_[+5(4.32e-06)]_37 chr12:8123378-8123458 9.52e-01 80 chr11:70588839-70588919 1.47e-03 22_[+2(1.94e-06)]_50 chr5:141736683-141736763 1.62e-04 15_[+5(5.49e-07)]_57 chr11:16626446-16626526 1.34e-02 40_[+3(1.14e-05)]_32 chr19:10654371-10654451 1.96e-03 22_[+2(2.63e-05)]_31_[+2(6.61e-06)]_\ 11 chr2:128165677-128165757 1.28e-02 24_[+1(1.56e-05)]_4_[+1(2.95e-05)]_\ 36 chr19:4328505-4328585 1.57e-01 80 chr19:13961338-13961418 2.57e-04 13_[+4(7.12e-06)]_33_[+1(1.56e-05)]_\ 18 chr14:75743875-75743955 1.08e-03 58_[+5(8.52e-06)]_14 chr12:50561212-50561292 7.20e-01 80 chr5:131831606-131831686 4.78e-01 80 chr12:122235204-12223528 9.85e-01 80 chr1:43423898-43423978 9.73e-01 80 chr9:126122587-126122667 2.49e-06 45_[+2(4.67e-06)]_27 chr19:13162620-13162700 1.98e-03 [+5(2.28e-06)]_72 chr5:39424988-39425068 9.63e-07 5_[+5(2.28e-06)]_43_[+2(4.56e-05)]_\ 16 chr1:2064732-2064812 9.81e-01 80 chr10:135059389-13505946 4.02e-02 45_[+2(4.56e-05)]_27 chr9:94662458-94662538 5.83e-01 80 chr5:177540454-177540534 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