******************************************************************************** MEME - Motif discovery tool ******************************************************************************** MEME version 5.3.3 (Release date: Sun Feb 7 15:39:52 2021 -0800) For further information on how to interpret these results please access https://meme-suite.org/meme. To get a copy of the MEME Suite software please access https://meme-suite.org. ******************************************************************************** ******************************************************************************** REFERENCE ******************************************************************************** If you use this program in your research, please cite: Timothy L. Bailey and Charles Elkan, "Fitting a mixture model by expectation maximization to discover motifs in biopolymers", Proceedings of the Second International Conference on Intelligent Systems for Molecular Biology, pp. 28-36, AAAI Press, Menlo Park, California, 1994. ******************************************************************************** ******************************************************************************** TRAINING SET ******************************************************************************** PRIMARY SEQUENCES= ../result/final_prediction/K562/fasta/RankLinear0.6_40/HLTF.fasta CONTROL SEQUENCES= --none-- ALPHABET= ACGT Sequence name Weight Length Sequence name Weight Length ------------- ------ ------ ------------- ------ ------ chr1:9156006-9156086 1.0000 80 chr19:6538032-6538112 1.0000 80 chr19:16055395-16055475 1.0000 80 chr2:228187424-228187504 1.0000 80 chr12:111210404-11121048 1.0000 80 chr2:10338784-10338864 1.0000 80 chr19:6578822-6578902 1.0000 80 chr7:1842784-1842864 1.0000 80 chr15:42317408-42317488 1.0000 80 chr1:207601336-207601416 1.0000 80 chr12:124312820-12431290 1.0000 80 chr20:49916866-49916946 1.0000 80 chr5:177368705-177368785 1.0000 80 chr11:62614312-62614392 1.0000 80 chr6:90029981-90030061 1.0000 80 chr7:129898505-129898585 1.0000 80 chr7:25235880-25235960 1.0000 80 chr17:47206866-47206946 1.0000 80 chr21:45344527-45344607 1.0000 80 chr13:42844807-42844887 1.0000 80 chr19:44151969-44152049 1.0000 80 chr1:241805477-241805557 1.0000 80 chrX:2526183-2526263 1.0000 80 chr2:7020366-7020446 1.0000 80 chr1:118241222-118241302 1.0000 80 chr1:118313911-118313991 1.0000 80 chr20:56111501-56111581 1.0000 80 chr1:16003873-16003953 1.0000 80 chr2:234159374-234159454 1.0000 80 chr22:24600668-24600748 1.0000 80 chr12:30937585-30937665 1.0000 80 chr6:166708989-166709069 1.0000 80 chr6:5324360-5324440 1.0000 80 chr7:1754578-1754658 1.0000 80 chr2:231187413-231187493 1.0000 80 chr1:1042038-1042118 1.0000 80 chr10:45782587-45782667 1.0000 80 chr21:45357337-45357417 1.0000 80 chr21:43780581-43780661 1.0000 80 chr10:45769964-45770044 1.0000 80 chr11:74577724-74577804 1.0000 80 chr1:247409763-247409843 1.0000 80 chr9:139588148-139588228 1.0000 80 chr1:17232264-17232344 1.0000 80 chr6:16040971-16041051 1.0000 80 chr11:124197843-12419792 1.0000 80 chr6:57404355-57404435 1.0000 80 chr19:39449070-39449150 1.0000 80 chr7:4659483-4659563 1.0000 80 chr12:93572044-93572124 1.0000 80 chr19:1935663-1935743 1.0000 80 chr19:2648757-2648837 1.0000 80 chr19:13388032-13388112 1.0000 80 chr2:54285755-54285835 1.0000 80 chr5:34915073-34915153 1.0000 80 chr12:94320139-94320219 1.0000 80 chr7:512381-512461 1.0000 80 chr4:171202332-171202412 1.0000 80 chr16:30124261-30124341 1.0000 80 chr6:6881104-6881184 1.0000 80 chr19:45539166-45539246 1.0000 80 chr19:8139556-8139636 1.0000 80 chr19:56485505-56485585 1.0000 80 chrX:67682584-67682664 1.0000 80 chr11:64094936-64095016 1.0000 80 chr7:3005558-3005638 1.0000 80 chr3:13307139-13307219 1.0000 80 chr4:25225527-25225607 1.0000 80 chr3:45112684-45112764 1.0000 80 chr1:16832994-16833074 1.0000 80 chr3:73194147-73194227 1.0000 80 chr13:41722988-41723068 1.0000 80 chrX:79568097-79568177 1.0000 80 chr16:11254668-11254748 1.0000 80 chr19:17635585-17635665 1.0000 80 chr11:60931369-60931449 1.0000 80 chr7:86957785-86957865 1.0000 80 chr17:47199231-47199311 1.0000 80 chr9:140188963-140189043 1.0000 80 chr9:125209614-125209694 1.0000 80 chr21:36396518-36396598 1.0000 80 chr7:102643617-102643697 1.0000 80 chr17:38917024-38917104 1.0000 80 chr22:19324830-19324910 1.0000 80 chr12:752552-752632 1.0000 80 chr19:5325108-5325188 1.0000 80 chr4:56150654-56150734 1.0000 80 chr11:67204070-67204150 1.0000 80 chr3:45114957-45115037 1.0000 80 chr18:77782838-77782918 1.0000 80 chr9:132617808-132617888 1.0000 80 chr10:73537145-73537225 1.0000 80 chr1:2522837-2522917 1.0000 80 chr15:75434985-75435065 1.0000 80 chr1:112290058-112290138 1.0000 80 chr6:35676527-35676607 1.0000 80 chr1:114022490-114022570 1.0000 80 chr1:233697733-233697813 1.0000 80 chr16:11301658-11301738 1.0000 80 chr9:131962687-131962767 1.0000 80 chr21:45864650-45864730 1.0000 80 chr1:22140232-22140312 1.0000 80 chr6:28756837-28756917 1.0000 80 chr10:58130633-58130713 1.0000 80 chr21:39601347-39601427 1.0000 80 chr19:6292194-6292274 1.0000 80 chr8:42979673-42979753 1.0000 80 chr20:60808917-60808997 1.0000 80 chr19:5991399-5991479 1.0000 80 chr19:17782915-17782995 1.0000 80 chr7:134841217-134841297 1.0000 80 chr2:6985640-6985720 1.0000 80 chr11:443639-443719 1.0000 80 chr22:19139213-19139293 1.0000 80 chr1:89383188-89383268 1.0000 80 chr5:175789039-175789119 1.0000 80 chr3:183371144-183371224 1.0000 80 chr19:45270716-45270796 1.0000 80 chr16:81792240-81792320 1.0000 80 chr7:6388788-6388868 1.0000 80 chr3:47575731-47575811 1.0000 80 chr10:73705784-73705864 1.0000 80 chr15:68196212-68196292 1.0000 80 chr19:11455379-11455459 1.0000 80 chr9:94467836-94467916 1.0000 80 chr1:15133402-15133482 1.0000 80 chr4:38300633-38300713 1.0000 80 chr7:635485-635565 1.0000 80 chr3:128578532-128578612 1.0000 80 chr7:64869076-64869156 1.0000 80 chr4:2433877-2433957 1.0000 80 chr4:6767580-6767660 1.0000 80 chr16:30826023-30826103 1.0000 80 chr22:23339495-23339575 1.0000 80 chr17:39607705-39607785 1.0000 80 chr7:149226346-149226426 1.0000 80 chr6:43866252-43866332 1.0000 80 chr19:5453181-5453261 1.0000 80 chr16:89152380-89152460 1.0000 80 chr19:17639571-17639651 1.0000 80 chr16:11704511-11704591 1.0000 80 chr19:38653472-38653552 1.0000 80 chr10:82256456-82256536 1.0000 80 chr11:64013432-64013512 1.0000 80 chr12:123315472-12331555 1.0000 80 chr8:607156-607236 1.0000 80 chr6:109657585-109657665 1.0000 80 chrX:47535781-47535861 1.0000 80 chr20:1168309-1168389 1.0000 80 chr19:14844508-14844588 1.0000 80 chr5:173309827-173309907 1.0000 80 chr4:190842393-190842473 1.0000 80 chr12:27972599-27972679 1.0000 80 chr2:170696379-170696459 1.0000 80 chr7:148600710-148600790 1.0000 80 chr7:150000279-150000359 1.0000 80 chr1:12623048-12623128 1.0000 80 chr7:2944807-2944887 1.0000 80 chr17:21135504-21135584 1.0000 80 chr6:14264263-14264343 1.0000 80 chr17:57028027-57028107 1.0000 80 chr12:116803030-11680311 1.0000 80 chr1:26042455-26042535 1.0000 80 chr1:20344426-20344506 1.0000 80 chr6:42679806-42679886 1.0000 80 chr3:58147485-58147565 1.0000 80 chr1:165667230-165667310 1.0000 80 chr12:112204235-11220431 1.0000 80 chr1:12275776-12275856 1.0000 80 chr6:13795380-13795460 1.0000 80 chr15:66981104-66981184 1.0000 80 chr7:71601964-71602044 1.0000 80 chr19:33382635-33382715 1.0000 80 chr6:27619265-27619345 1.0000 80 chr2:103417745-103417825 1.0000 80 chr5:170253295-170253375 1.0000 80 chr10:87571316-87571396 1.0000 80 chr11:118505372-11850545 1.0000 80 chr1:162446583-162446663 1.0000 80 chr17:961813-961893 1.0000 80 chr6:44027521-44027601 1.0000 80 chr19:45218148-45218228 1.0000 80 chr7:67128758-67128838 1.0000 80 chr19:41331548-41331628 1.0000 80 chr3:139808701-139808781 1.0000 80 chr6:27511942-27512022 1.0000 80 chr17:65990196-65990276 1.0000 80 chr19:1795784-1795864 1.0000 80 chr4:128670246-128670326 1.0000 80 chr7:100497218-100497298 1.0000 80 chr7:73632786-73632866 1.0000 80 chr6:26322678-26322758 1.0000 80 chr21:38751256-38751336 1.0000 80 chr3:14162293-14162373 1.0000 80 chr22:21452600-21452680 1.0000 80 chr11:70079298-70079378 1.0000 80 chr1:229922905-229922985 1.0000 80 chr21:16018170-16018250 1.0000 80 chr12:63548477-63548557 1.0000 80 chr19:4811945-4812025 1.0000 80 chr22:19304394-19304474 1.0000 80 chr5:139990644-139990724 1.0000 80 chr20:48816382-48816462 1.0000 80 chr10:74397398-74397478 1.0000 80 chr19:4233550-4233630 1.0000 80 chr7:106256942-106257022 1.0000 80 chr16:85151775-85151855 1.0000 80 chr19:13001400-13001480 1.0000 80 chr22:19152063-19152143 1.0000 80 chr16:15744548-15744628 1.0000 80 chr1:221915134-221915214 1.0000 80 chr12:9297109-9297189 1.0000 80 chr10:5207846-5207926 1.0000 80 chr1:151880040-151880120 1.0000 80 chr6:27182739-27182819 1.0000 80 chr5:180645580-180645660 1.0000 80 chr8:896896-896976 1.0000 80 chr16:53086977-53087057 1.0000 80 chr20:43591260-43591340 1.0000 80 chr9:132237421-132237501 1.0000 80 chr9:129699882-129699962 1.0000 80 chr16:84884475-84884555 1.0000 80 chr19:35738564-35738644 1.0000 80 chr7:97069109-97069189 1.0000 80 chr1:32403138-32403218 1.0000 80 chr1:53671903-53671983 1.0000 80 chr6:24479522-24479602 1.0000 80 chr2:10260143-10260223 1.0000 80 chr3:167436486-167436566 1.0000 80 chr7:18121376-18121456 1.0000 80 chr2:174163435-174163515 1.0000 80 chr6:28758288-28758368 1.0000 80 chr6:88437862-88437942 1.0000 80 chr5:122961928-122962008 1.0000 80 chr8:124073077-124073157 1.0000 80 chr1:199928664-199928744 1.0000 80 chr22:19804120-19804200 1.0000 80 chr16:85279491-85279571 1.0000 80 chr16:85396208-85396288 1.0000 80 chr1:201405039-201405119 1.0000 80 chr22:20104407-20104487 1.0000 80 chr16:81611545-81611625 1.0000 80 chr3:194871515-194871595 1.0000 80 chr5:96143817-96143897 1.0000 80 chr7:152160587-152160667 1.0000 80 chr10:43876061-43876141 1.0000 80 chr6:30654128-30654208 1.0000 80 chr6:44012289-44012369 1.0000 80 chr1:11125167-11125247 1.0000 80 chr6:42533270-42533350 1.0000 80 ******************************************************************************** ******************************************************************************** COMMAND LINE SUMMARY ******************************************************************************** This information can also be useful in the event you wish to report a problem with the MEME software. command: meme -oc ../result/final_prediction/K562/inference_raw/MEME/RankLinear0.6_40_HLTF/ -dna -nmotifs 5 -w 8 -maxsize 250000 -nostatus ../result/final_prediction/K562/fasta/RankLinear0.6_40/HLTF.fasta model: mod= zoops nmotifs= 5 evt= inf objective function: em= E-value of product of p-values starts= E-value of product of p-values strands: + width: minw= 8 maxw= 8 nsites: minsites= 2 maxsites= 250 wnsites= 0.8 theta: spmap= uni spfuzz= 0.5 em: prior= dirichlet b= 0.01 maxiter= 50 distance= 1e-05 trim: wg= 11 ws= 1 endgaps= yes data: n= 20000 N= 250 sample: seed= 0 hsfrac= 0 searchsize= 20000 norand= no csites= 1000 Letter frequencies in dataset: A 0.279 C 0.237 G 0.229 T 0.254 Background letter frequencies (from file dataset with add-one prior applied): A 0.279 C 0.238 G 0.229 T 0.254 Background model order: 0 ******************************************************************************** ******************************************************************************** MOTIF GGTTTATT MEME-1 width = 8 sites = 55 llr = 544 E-value = 6.4e-061 ******************************************************************************** -------------------------------------------------------------------------------- Motif GGTTTATT MEME-1 Description -------------------------------------------------------------------------------- Simplified A :1:::9:: pos.-specific C ::::::1: probability G a9:::1:: matrix T ::aaa:9a bits 2.1 * 1.9 * ** * 1.7 ***** * 1.5 ***** ** Relative 1.3 ******** Entropy 1.1 ******** (14.3 bits) 0.8 ******** 0.6 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel GGTTTATT consensus sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GGTTTATT MEME-1 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr12:9297109-9297189 62 1.55e-05 gtcaaagaca ggtttatt ttggagaata chr5:139990644-139990724 26 1.55e-05 aacaaagaca ggtttatt ttggagcata chr12:63548477-63548557 11 1.55e-05 gcccctctca ggtttatt ctccaaaata chr1:229922905-229922985 48 1.55e-05 gtcaaagaca ggtttatt ctggagaata chr3:14162293-14162373 60 1.55e-05 aacagggaca ggtttatt ttaaacaaac chr3:139808701-139808781 54 1.55e-05 gttaaaggaa ggtttatt ttagagaaaa chr5:170253295-170253375 42 1.55e-05 gtcaaagaca ggtttatt ttagagagat chr7:71601964-71602044 28 1.55e-05 gttaaggaca ggtttatt ttagagaaaa chr12:27972599-27972679 63 1.55e-05 cacaaggaca ggtttatt ttaggaaaca chr8:607156-607236 50 1.55e-05 gtctaagaca ggtttatt ttggagaata chr17:39607705-39607785 25 1.55e-05 gcctctctca ggtttatt ctccaaaata chr1:2522837-2522917 34 1.55e-05 gcccctctca ggtttatt cccaaaataa chr9:125209614-125209694 14 1.55e-05 gcccctctca ggtttatt ctccaaaata chr17:47199231-47199311 52 1.55e-05 gttaaagtca ggtttatt ttggagaata chr19:56485505-56485585 58 1.55e-05 gttaaggaca ggtttatt ttagagaaaa chr12:94320139-94320219 17 1.55e-05 gcccctctca ggtttatt taaaataaac chr12:93572044-93572124 2 1.55e-05 g ggtttatt ctccaaaata chr6:57404355-57404435 41 1.55e-05 gtcaaagaca ggtttatt ttggagaata chr10:45769964-45770044 52 1.55e-05 gtcaaagaca ggtttatt ttggagaata chr10:45782587-45782667 41 1.55e-05 gtcaaagaca ggtttatt ttggagaata chr2:231187413-231187493 13 1.55e-05 tcccctctca ggtttatt ctccaaaata chr6:166708989-166709069 13 1.55e-05 gcccctctca ggtttatt ctctaaaata chr22:24600668-24600748 13 1.55e-05 gcccctctca ggtttatt ctctagaata chr2:234159374-234159454 47 1.55e-05 atcaaagaca ggtttatt ttggagaata chr2:7020366-7020446 30 1.55e-05 gtcaaggaca ggtttatt ttagagaaaa chr19:44151969-44152049 61 1.55e-05 gtgaaggaca ggtttatt ttagagaaaa chr17:47206866-47206946 73 1.55e-05 aacagtcaaa ggtttatt chr7:25235880-25235960 65 1.55e-05 gttaaggaca ggtttatt ttagagaa chr6:90029981-90030061 18 1.55e-05 gcccctctca ggtttatt ctccaaaata chr12:124312820-12431290 64 1.55e-05 agtcaaaaca ggtttatt ttagagaaa chr1:207601336-207601416 62 1.55e-05 gttaaggacg ggtttatt ttagagaaaa chr7:1842784-1842864 47 1.55e-05 gtcagagaca ggtttatt ttggaggaat chr19:6578822-6578902 58 1.55e-05 gtcaaagacg ggtttatt ttggagaata chr2:10338784-10338864 36 1.55e-05 gtccaagaca ggtttatt ttggagaata chr12:111210404-11121048 51 1.55e-05 agtcaagaca ggtttatt ttagagaaaa chr2:228187424-228187504 45 1.55e-05 atcaaggata ggtttatt ttagagaata chr19:6538032-6538112 49 1.55e-05 gtcaaggaca ggtttatt ttagagaaaa chr6:24479522-24479602 26 3.00e-05 gcccctctca ggtttact tctccaaaat chr15:68196212-68196292 55 3.00e-05 agtaaagaca ggtttact ttagataaaa chr2:54285755-54285835 49 3.00e-05 agttaagaca ggtttact ttagataaaa chr20:49916866-49916946 36 3.00e-05 gttaaagaca ggtttact ttagataaaa chr15:42317408-42317488 68 3.00e-05 cagtaagaca ggtttact taagg chr19:16055395-16055475 34 3.00e-05 gttaaagaca ggtttact ttagataaaa chrX:47535781-47535861 19 4.27e-05 tcccctgtca ggtttgtt ttctctaaaa chrX:79568097-79568177 14 4.27e-05 gcccctctca ggtttgtt ttctctaaaa chr20:56111501-56111581 13 4.27e-05 gtccctctca ggtttgtt ttctctaaaa chr1:9156006-9156086 2 4.27e-05 a ggtttgtt ttctctaaaa chr7:97069109-97069189 34 6.15e-05 gaaataggag gatttatt gaattcactc chr2:170696379-170696459 55 6.15e-05 ggtcaagaca gatttatt ttagagaaaa chr1:16832994-16833074 25 6.15e-05 ggaacaggag gatttatt gactgcactc chr4:25225527-25225607 29 6.15e-05 gagataggag gatttatt gagtgcactc chr7:67128758-67128838 70 7.60e-05 ggttaagaca ggcttatt tta chr19:39449070-39449150 44 7.60e-05 gtcaaagaca ggcttatt ttggagaata chr16:30826023-30826103 20 9.01e-05 AGGACAGGGA GGTTTTtt ccttccttcc chr7:134841217-134841297 49 1.04e-04 ttgagcatat ggtgtatt tccttcaatg -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GGTTTATT MEME-1 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr12:9297109-9297189 1.5e-05 61_[+1]_11 chr5:139990644-139990724 1.5e-05 25_[+1]_47 chr12:63548477-63548557 1.5e-05 10_[+1]_62 chr1:229922905-229922985 1.5e-05 47_[+1]_25 chr3:14162293-14162373 1.5e-05 59_[+1]_13 chr3:139808701-139808781 1.5e-05 53_[+1]_19 chr5:170253295-170253375 1.5e-05 41_[+1]_31 chr7:71601964-71602044 1.5e-05 27_[+1]_45 chr12:27972599-27972679 1.5e-05 62_[+1]_10 chr8:607156-607236 1.5e-05 49_[+1]_23 chr17:39607705-39607785 1.5e-05 24_[+1]_48 chr1:2522837-2522917 1.5e-05 33_[+1]_39 chr9:125209614-125209694 1.5e-05 13_[+1]_59 chr17:47199231-47199311 1.5e-05 51_[+1]_21 chr19:56485505-56485585 1.5e-05 57_[+1]_15 chr12:94320139-94320219 1.5e-05 16_[+1]_56 chr12:93572044-93572124 1.5e-05 1_[+1]_71 chr6:57404355-57404435 1.5e-05 40_[+1]_32 chr10:45769964-45770044 1.5e-05 51_[+1]_21 chr10:45782587-45782667 1.5e-05 40_[+1]_32 chr2:231187413-231187493 1.5e-05 12_[+1]_60 chr6:166708989-166709069 1.5e-05 12_[+1]_60 chr22:24600668-24600748 1.5e-05 12_[+1]_60 chr2:234159374-234159454 1.5e-05 46_[+1]_26 chr2:7020366-7020446 1.5e-05 29_[+1]_43 chr19:44151969-44152049 1.5e-05 60_[+1]_12 chr17:47206866-47206946 1.5e-05 72_[+1] chr7:25235880-25235960 1.5e-05 64_[+1]_8 chr6:90029981-90030061 1.5e-05 17_[+1]_55 chr12:124312820-12431290 1.5e-05 63_[+1]_9 chr1:207601336-207601416 1.5e-05 61_[+1]_11 chr7:1842784-1842864 1.5e-05 46_[+1]_26 chr19:6578822-6578902 1.5e-05 57_[+1]_15 chr2:10338784-10338864 1.5e-05 35_[+1]_37 chr12:111210404-11121048 1.5e-05 50_[+1]_22 chr2:228187424-228187504 1.5e-05 44_[+1]_28 chr19:6538032-6538112 1.5e-05 48_[+1]_24 chr6:24479522-24479602 3e-05 25_[+1]_47 chr15:68196212-68196292 3e-05 54_[+1]_18 chr2:54285755-54285835 3e-05 48_[+1]_24 chr20:49916866-49916946 3e-05 35_[+1]_37 chr15:42317408-42317488 3e-05 67_[+1]_5 chr19:16055395-16055475 3e-05 33_[+1]_39 chrX:47535781-47535861 4.3e-05 18_[+1]_54 chrX:79568097-79568177 4.3e-05 13_[+1]_59 chr20:56111501-56111581 4.3e-05 12_[+1]_60 chr1:9156006-9156086 4.3e-05 1_[+1]_71 chr7:97069109-97069189 6.2e-05 33_[+1]_39 chr2:170696379-170696459 6.2e-05 54_[+1]_18 chr1:16832994-16833074 6.2e-05 24_[+1]_48 chr4:25225527-25225607 6.2e-05 28_[+1]_44 chr7:67128758-67128838 7.6e-05 69_[+1]_3 chr19:39449070-39449150 7.6e-05 43_[+1]_29 chr16:30826023-30826103 9e-05 19_[+1]_53 chr7:134841217-134841297 0.0001 48_[+1]_24 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GGTTTATT MEME-1 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF GGTTTATT width=8 seqs=55 chr12:9297109-9297189 ( 62) GGTTTATT 1 chr5:139990644-139990724 ( 26) GGTTTATT 1 chr12:63548477-63548557 ( 11) GGTTTATT 1 chr1:229922905-229922985 ( 48) GGTTTATT 1 chr3:14162293-14162373 ( 60) GGTTTATT 1 chr3:139808701-139808781 ( 54) GGTTTATT 1 chr5:170253295-170253375 ( 42) GGTTTATT 1 chr7:71601964-71602044 ( 28) GGTTTATT 1 chr12:27972599-27972679 ( 63) GGTTTATT 1 chr8:607156-607236 ( 50) GGTTTATT 1 chr17:39607705-39607785 ( 25) GGTTTATT 1 chr1:2522837-2522917 ( 34) GGTTTATT 1 chr9:125209614-125209694 ( 14) GGTTTATT 1 chr17:47199231-47199311 ( 52) GGTTTATT 1 chr19:56485505-56485585 ( 58) GGTTTATT 1 chr12:94320139-94320219 ( 17) GGTTTATT 1 chr12:93572044-93572124 ( 2) GGTTTATT 1 chr6:57404355-57404435 ( 41) GGTTTATT 1 chr10:45769964-45770044 ( 52) GGTTTATT 1 chr10:45782587-45782667 ( 41) GGTTTATT 1 chr2:231187413-231187493 ( 13) GGTTTATT 1 chr6:166708989-166709069 ( 13) GGTTTATT 1 chr22:24600668-24600748 ( 13) GGTTTATT 1 chr2:234159374-234159454 ( 47) GGTTTATT 1 chr2:7020366-7020446 ( 30) GGTTTATT 1 chr19:44151969-44152049 ( 61) GGTTTATT 1 chr17:47206866-47206946 ( 73) GGTTTATT 1 chr7:25235880-25235960 ( 65) GGTTTATT 1 chr6:90029981-90030061 ( 18) GGTTTATT 1 chr12:124312820-12431290 ( 64) GGTTTATT 1 chr1:207601336-207601416 ( 62) GGTTTATT 1 chr7:1842784-1842864 ( 47) GGTTTATT 1 chr19:6578822-6578902 ( 58) GGTTTATT 1 chr2:10338784-10338864 ( 36) GGTTTATT 1 chr12:111210404-11121048 ( 51) GGTTTATT 1 chr2:228187424-228187504 ( 45) GGTTTATT 1 chr19:6538032-6538112 ( 49) GGTTTATT 1 chr6:24479522-24479602 ( 26) GGTTTACT 1 chr15:68196212-68196292 ( 55) GGTTTACT 1 chr2:54285755-54285835 ( 49) GGTTTACT 1 chr20:49916866-49916946 ( 36) GGTTTACT 1 chr15:42317408-42317488 ( 68) GGTTTACT 1 chr19:16055395-16055475 ( 34) GGTTTACT 1 chrX:47535781-47535861 ( 19) GGTTTGTT 1 chrX:79568097-79568177 ( 14) GGTTTGTT 1 chr20:56111501-56111581 ( 13) GGTTTGTT 1 chr1:9156006-9156086 ( 2) GGTTTGTT 1 chr7:97069109-97069189 ( 34) GATTTATT 1 chr2:170696379-170696459 ( 55) GATTTATT 1 chr1:16832994-16833074 ( 25) GATTTATT 1 chr4:25225527-25225607 ( 29) GATTTATT 1 chr7:67128758-67128838 ( 70) GGCTTATT 1 chr19:39449070-39449150 ( 44) GGCTTATT 1 chr16:30826023-30826103 ( 20) GGTTTTTT 1 chr7:134841217-134841297 ( 49) GGTGTATT 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GGTTTATT MEME-1 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 8.95894 E= 6.4e-061 -1243 -1243 212 -1243 -194 -1243 202 -1243 -1243 -271 -1243 192 -1243 -1243 -365 195 -1243 -1243 -1243 198 170 -1243 -166 -380 -1243 -112 -1243 181 -1243 -1243 -1243 198 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GGTTTATT MEME-1 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 55 E= 6.4e-061 0.000000 0.000000 1.000000 0.000000 0.072727 0.000000 0.927273 0.000000 0.000000 0.036364 0.000000 0.963636 0.000000 0.000000 0.018182 0.981818 0.000000 0.000000 0.000000 1.000000 0.909091 0.000000 0.072727 0.018182 0.000000 0.109091 0.000000 0.890909 0.000000 0.000000 0.000000 1.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GGTTTATT MEME-1 regular expression -------------------------------------------------------------------------------- GGTTTATT -------------------------------------------------------------------------------- Time 5.11 secs. ******************************************************************************** ******************************************************************************** MOTIF AAAKAAAC MEME-2 width = 8 sites = 70 llr = 572 E-value = 9.9e-036 ******************************************************************************** -------------------------------------------------------------------------------- Motif AAAKAAAC MEME-2 Description -------------------------------------------------------------------------------- Simplified A 9aa:a9a: pos.-specific C :::1:1:8 probability G 1::5:::2 matrix T :::4:::: bits 2.1 1.9 * * 1.7 ** * * 1.5 *** *** Relative 1.3 *** *** Entropy 1.1 *** **** (11.8 bits) 0.8 *** **** 0.6 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel AAAGAAAC consensus T sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAAKAAAC MEME-2 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr12:9297109-9297189 26 2.57e-05 aagaaagagg aaagaaac acgattagtg chr1:229922905-229922985 12 2.57e-05 aagaaagaag aaagaaac acaaaaagca chr3:139808701-139808781 18 2.57e-05 aagaaagggg aaagaaac acaaaacatg chr7:67128758-67128838 35 2.57e-05 aagaaagagg aaagaaac acaaaaggtg chr2:170696379-170696459 20 2.57e-05 aagaaagagg aaagaaac acgaaaggtg chr8:607156-607236 14 2.57e-05 gttgaagaag aaagaaac acgaaaagca chr15:68196212-68196292 20 2.57e-05 GTAagagagg aaagaaac acaaactgca chr17:47199231-47199311 16 2.57e-05 aagaaagagg aaagaaac acgaaaaatg chr19:56485505-56485585 22 2.57e-05 aagaaagagg aaagaaac acaaaaggtg chr2:54285755-54285835 14 2.57e-05 aagaaagagg aaagaaac acaaaatgtg chr19:39449070-39449150 8 2.57e-05 aaagagg aaagaaac acgaaaagtg chr6:57404355-57404435 5 2.57e-05 gagg aaagaaac acgaaaagca chr10:45782587-45782667 5 2.57e-05 gagg aaagaaac acaaaaagtg chr2:234159374-234159454 11 2.57e-05 aagaaacaag aaagaaac acgaaaagca chr1:241805477-241805557 47 2.57e-05 aagaaagagg aaagaaac actaatagca chr19:44151969-44152049 25 2.57e-05 aaggaaaagg aaagaaac atgaaatgtg chr17:47206866-47206946 41 2.57e-05 aagaaagagg aaagaaac acaaaaagtg chr7:25235880-25235960 29 2.57e-05 aagaaagagg aaagaaac acaaaaggtg chr11:62614312-62614392 1 2.57e-05 . aaagaaac acgaaatgtg chr12:124312820-12431290 29 2.57e-05 aagaaagagg aaagaaac acaaaaggtg chr15:42317408-42317488 34 2.57e-05 aagaaagagg aaagaaac atgaaaggtg chr7:1842784-1842864 11 2.57e-05 cacaaagagg aaagaaac acaaaaagca chr19:6578822-6578902 22 2.57e-05 aagaaagaga aaagaaac acgaaaaggg chr12:111210404-11121048 16 2.57e-05 aagaaagagg aaagaaac atgaaaggtg chr19:6538032-6538112 13 2.57e-05 aagaaagagg aaagaaac atgaaaggtg chr12:63548477-63548557 24 5.42e-05 ttattctcca aaataaac ctgtctttga chr19:14844508-14844588 23 5.42e-05 gttttctcta aaataaac ctgtcttaac chrX:47535781-47535861 34 5.42e-05 gttttctcta aaataaac ctgtccttga chr17:39607705-39607785 38 5.42e-05 ttattctcca aaataaac ctgtctttga chr1:2522837-2522917 46 5.42e-05 tttattccca aaataaac ctgtctctgt chr9:125209614-125209694 27 5.42e-05 ttattctcca aaataaac ctctctttga chrX:79568097-79568177 29 5.42e-05 gttttctcta aaataaac ctgtccttga chr4:171202332-171202412 20 5.42e-05 gttttatcta aaataaac ccatctttac chr12:94320139-94320219 27 5.42e-05 ggtttattta aaataaac ttgtccccgt chr12:93572044-93572124 15 5.42e-05 ttattctcca aaataaac ctgtttttaa chr2:231187413-231187493 26 5.42e-05 ttattctcca aaataaac ctgtctttaa chr6:166708989-166709069 26 5.42e-05 ttattctcta aaataaac ctgtctttga chr13:42844807-42844887 13 5.42e-05 ttattctcca aaataaac ctgtctctgt chr6:90029981-90030061 31 5.42e-05 ttattctcca aaataaac ctgtctttga chr5:177368705-177368785 37 5.42e-05 cccaggtttg aaataaac ctgctgactg chr1:9156006-9156086 17 5.42e-05 gttttctcta aaataaac ctgtccttaa chr10:87571316-87571396 47 7.90e-05 agaccaagca aaagaaag aatttctaaa chr12:27972599-27972679 13 7.90e-05 tgtaagaatt aaagaaag aggagagaaa chr10:45769964-45770044 6 7.90e-05 gagtt aaagaaag aggaacaaac chr1:207601336-207601416 15 7.90e-05 tgtaagaatt aaagaaag aggaaagata chr1:233697733-233697813 20 1.06e-04 atgaaataaa aaataaag tcaagagctt chr19:45270716-45270796 59 1.27e-04 ccactgggaa gaagaaac aaaagtcaat chr10:43876061-43876141 73 1.54e-04 aactaaaaca aaacaaac chr3:14162293-14162373 70 1.54e-04 ggtttatttt aaacaaac ctg chr7:71601964-71602044 43 1.54e-04 attttagaga aaacaaac ctgagagggg chr6:28756837-28756917 24 1.54e-04 aacaaaaaac aaacaaac aaaaaagaTG chr22:24600668-24600748 26 1.78e-04 ttattctcta gaataaac ctgtctttaa chr2:10338784-10338864 49 1.78e-04 ttattttgga gaataaac ctgagagggg chr2:228187424-228187504 58 1.78e-04 ttattttaga gaataaac ctgagagggg chr12:116803030-11680311 3 2.31e-04 ac aaaaaaac taagtgggaa chr22:19324830-19324910 35 2.31e-04 tctggaaata aaagacac acttagagaa chr2:7020366-7020446 45 2.31e-04 attttagaga aaaaaaac ctgagagggg chr4:190842393-190842473 72 2.55e-04 ggctctttga aaatacac t chr5:122961928-122962008 36 3.04e-04 ttgatcaagc aaagaaat aatctgtgaa chr21:16018170-16018250 65 3.24e-04 tgtataagca gaagaaag aattagtg chr4:38300633-38300713 71 3.24e-04 cagttaagca gaagaaag aa chr6:24479522-24479602 40 3.78e-04 tacttctcca aaataaat ctgtctttga chr6:5324360-5324440 23 3.78e-04 gttttatcta aagtaaac cggtctttaa chr12:30937585-30937665 34 3.78e-04 gttttatcaa aagtaaac ctgtctttac chr6:44027521-44027601 20 4.26e-04 gacccccatg gaataaag actagactac chr1:201405039-201405119 50 4.47e-04 gAagagagag agagaaac agagagagaa chr7:106256942-106257022 69 5.29e-04 GGGTGGGAGG AAAAAAAG AAGG chr2:103417745-103417825 59 5.29e-04 ggcccagaac aaagacag ctcttgaact chr22:19152063-19152143 42 6.31e-04 gcaacatgag aaataaaa aattccctaa chr6:42679806-42679886 22 6.31e-04 gtttatgagg aaatacag gggacagaag -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAAKAAAC MEME-2 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr12:9297109-9297189 2.6e-05 25_[+2]_47 chr1:229922905-229922985 2.6e-05 11_[+2]_61 chr3:139808701-139808781 2.6e-05 17_[+2]_55 chr7:67128758-67128838 2.6e-05 34_[+2]_38 chr2:170696379-170696459 2.6e-05 19_[+2]_53 chr8:607156-607236 2.6e-05 13_[+2]_59 chr15:68196212-68196292 2.6e-05 19_[+2]_53 chr17:47199231-47199311 2.6e-05 15_[+2]_57 chr19:56485505-56485585 2.6e-05 21_[+2]_51 chr2:54285755-54285835 2.6e-05 13_[+2]_59 chr19:39449070-39449150 2.6e-05 7_[+2]_65 chr6:57404355-57404435 2.6e-05 4_[+2]_68 chr10:45782587-45782667 2.6e-05 4_[+2]_68 chr2:234159374-234159454 2.6e-05 10_[+2]_62 chr1:241805477-241805557 2.6e-05 46_[+2]_26 chr19:44151969-44152049 2.6e-05 24_[+2]_48 chr17:47206866-47206946 2.6e-05 40_[+2]_32 chr7:25235880-25235960 2.6e-05 28_[+2]_44 chr11:62614312-62614392 2.6e-05 [+2]_72 chr12:124312820-12431290 2.6e-05 28_[+2]_44 chr15:42317408-42317488 2.6e-05 33_[+2]_39 chr7:1842784-1842864 2.6e-05 10_[+2]_62 chr19:6578822-6578902 2.6e-05 21_[+2]_51 chr12:111210404-11121048 2.6e-05 15_[+2]_57 chr19:6538032-6538112 2.6e-05 12_[+2]_60 chr12:63548477-63548557 5.4e-05 23_[+2]_49 chr19:14844508-14844588 5.4e-05 22_[+2]_50 chrX:47535781-47535861 5.4e-05 33_[+2]_39 chr17:39607705-39607785 5.4e-05 37_[+2]_35 chr1:2522837-2522917 5.4e-05 45_[+2]_27 chr9:125209614-125209694 5.4e-05 26_[+2]_46 chrX:79568097-79568177 5.4e-05 28_[+2]_44 chr4:171202332-171202412 5.4e-05 19_[+2]_53 chr12:94320139-94320219 5.4e-05 26_[+2]_46 chr12:93572044-93572124 5.4e-05 14_[+2]_58 chr2:231187413-231187493 5.4e-05 25_[+2]_47 chr6:166708989-166709069 5.4e-05 25_[+2]_47 chr13:42844807-42844887 5.4e-05 12_[+2]_60 chr6:90029981-90030061 5.4e-05 30_[+2]_42 chr5:177368705-177368785 5.4e-05 36_[+2]_36 chr1:9156006-9156086 5.4e-05 16_[+2]_56 chr10:87571316-87571396 7.9e-05 46_[+2]_26 chr12:27972599-27972679 7.9e-05 12_[+2]_60 chr10:45769964-45770044 7.9e-05 5_[+2]_67 chr1:207601336-207601416 7.9e-05 14_[+2]_58 chr1:233697733-233697813 0.00011 19_[+2]_53 chr19:45270716-45270796 0.00013 58_[+2]_14 chr10:43876061-43876141 0.00015 72_[+2] chr3:14162293-14162373 0.00015 69_[+2]_3 chr7:71601964-71602044 0.00015 42_[+2]_30 chr6:28756837-28756917 0.00015 23_[+2]_49 chr22:24600668-24600748 0.00018 25_[+2]_47 chr2:10338784-10338864 0.00018 48_[+2]_24 chr2:228187424-228187504 0.00018 57_[+2]_15 chr12:116803030-11680311 0.00023 2_[+2]_70 chr22:19324830-19324910 0.00023 34_[+2]_38 chr2:7020366-7020446 0.00023 44_[+2]_28 chr4:190842393-190842473 0.00026 71_[+2]_1 chr5:122961928-122962008 0.0003 35_[+2]_37 chr21:16018170-16018250 0.00032 64_[+2]_8 chr4:38300633-38300713 0.00032 70_[+2]_2 chr6:24479522-24479602 0.00038 39_[+2]_33 chr6:5324360-5324440 0.00038 22_[+2]_50 chr12:30937585-30937665 0.00038 33_[+2]_39 chr6:44027521-44027601 0.00043 19_[+2]_53 chr1:201405039-201405119 0.00045 49_[+2]_23 chr7:106256942-106257022 0.00053 68_[+2]_4 chr2:103417745-103417825 0.00053 58_[+2]_14 chr22:19152063-19152143 0.00063 41_[+2]_31 chr6:42679806-42679886 0.00063 21_[+2]_51 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAAKAAAC MEME-2 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF AAAKAAAC width=8 seqs=70 chr12:9297109-9297189 ( 26) AAAGAAAC 1 chr1:229922905-229922985 ( 12) AAAGAAAC 1 chr3:139808701-139808781 ( 18) AAAGAAAC 1 chr7:67128758-67128838 ( 35) AAAGAAAC 1 chr2:170696379-170696459 ( 20) AAAGAAAC 1 chr8:607156-607236 ( 14) AAAGAAAC 1 chr15:68196212-68196292 ( 20) AAAGAAAC 1 chr17:47199231-47199311 ( 16) AAAGAAAC 1 chr19:56485505-56485585 ( 22) AAAGAAAC 1 chr2:54285755-54285835 ( 14) AAAGAAAC 1 chr19:39449070-39449150 ( 8) AAAGAAAC 1 chr6:57404355-57404435 ( 5) AAAGAAAC 1 chr10:45782587-45782667 ( 5) AAAGAAAC 1 chr2:234159374-234159454 ( 11) AAAGAAAC 1 chr1:241805477-241805557 ( 47) AAAGAAAC 1 chr19:44151969-44152049 ( 25) AAAGAAAC 1 chr17:47206866-47206946 ( 41) AAAGAAAC 1 chr7:25235880-25235960 ( 29) AAAGAAAC 1 chr11:62614312-62614392 ( 1) AAAGAAAC 1 chr12:124312820-12431290 ( 29) AAAGAAAC 1 chr15:42317408-42317488 ( 34) AAAGAAAC 1 chr7:1842784-1842864 ( 11) AAAGAAAC 1 chr19:6578822-6578902 ( 22) AAAGAAAC 1 chr12:111210404-11121048 ( 16) AAAGAAAC 1 chr19:6538032-6538112 ( 13) AAAGAAAC 1 chr12:63548477-63548557 ( 24) AAATAAAC 1 chr19:14844508-14844588 ( 23) AAATAAAC 1 chrX:47535781-47535861 ( 34) AAATAAAC 1 chr17:39607705-39607785 ( 38) AAATAAAC 1 chr1:2522837-2522917 ( 46) AAATAAAC 1 chr9:125209614-125209694 ( 27) AAATAAAC 1 chrX:79568097-79568177 ( 29) AAATAAAC 1 chr4:171202332-171202412 ( 20) AAATAAAC 1 chr12:94320139-94320219 ( 27) AAATAAAC 1 chr12:93572044-93572124 ( 15) AAATAAAC 1 chr2:231187413-231187493 ( 26) AAATAAAC 1 chr6:166708989-166709069 ( 26) AAATAAAC 1 chr13:42844807-42844887 ( 13) AAATAAAC 1 chr6:90029981-90030061 ( 31) AAATAAAC 1 chr5:177368705-177368785 ( 37) AAATAAAC 1 chr1:9156006-9156086 ( 17) AAATAAAC 1 chr10:87571316-87571396 ( 47) AAAGAAAG 1 chr12:27972599-27972679 ( 13) AAAGAAAG 1 chr10:45769964-45770044 ( 6) AAAGAAAG 1 chr1:207601336-207601416 ( 15) AAAGAAAG 1 chr1:233697733-233697813 ( 20) AAATAAAG 1 chr19:45270716-45270796 ( 59) GAAGAAAC 1 chr10:43876061-43876141 ( 73) AAACAAAC 1 chr3:14162293-14162373 ( 70) AAACAAAC 1 chr7:71601964-71602044 ( 43) AAACAAAC 1 chr6:28756837-28756917 ( 24) AAACAAAC 1 chr22:24600668-24600748 ( 26) GAATAAAC 1 chr2:10338784-10338864 ( 49) GAATAAAC 1 chr2:228187424-228187504 ( 58) GAATAAAC 1 chr12:116803030-11680311 ( 3) AAAAAAAC 1 chr22:19324830-19324910 ( 35) AAAGACAC 1 chr2:7020366-7020446 ( 45) AAAAAAAC 1 chr4:190842393-190842473 ( 72) AAATACAC 1 chr5:122961928-122962008 ( 36) AAAGAAAT 1 chr21:16018170-16018250 ( 65) GAAGAAAG 1 chr4:38300633-38300713 ( 71) GAAGAAAG 1 chr6:24479522-24479602 ( 40) AAATAAAT 1 chr6:5324360-5324440 ( 23) AAGTAAAC 1 chr12:30937585-30937665 ( 34) AAGTAAAC 1 chr6:44027521-44027601 ( 20) GAATAAAG 1 chr1:201405039-201405119 ( 50) AGAGAAAC 1 chr7:106256942-106257022 ( 69) AAAAAAAG 1 chr2:103417745-103417825 ( 59) AAAGACAG 1 chr22:19152063-19152143 ( 42) AAATAAAA 1 chr6:42679806-42679886 ( 22) AAATACAG 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAAKAAAC MEME-2 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 8.12365 E= 9.9e-036 169 -1277 -120 -1277 182 -1277 -400 -1277 180 -1277 -300 -1277 -270 -205 117 60 184 -1277 -1277 -1277 176 -205 -1277 -1277 184 -1277 -1277 -1277 -428 175 -54 -315 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAAKAAAC MEME-2 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 70 E= 9.9e-036 0.900000 0.000000 0.100000 0.000000 0.985714 0.000000 0.014286 0.000000 0.971429 0.000000 0.028571 0.000000 0.042857 0.057143 0.514286 0.385714 1.000000 0.000000 0.000000 0.000000 0.942857 0.057143 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.014286 0.800000 0.157143 0.028571 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAAKAAAC MEME-2 regular expression -------------------------------------------------------------------------------- AAA[GT]AAAC -------------------------------------------------------------------------------- Time 8.83 secs. ******************************************************************************** ******************************************************************************** MOTIF RTGGCTGS MEME-3 width = 8 sites = 83 llr = 623 E-value = 4.6e-028 ******************************************************************************** -------------------------------------------------------------------------------- Motif RTGGCTGS MEME-3 Description -------------------------------------------------------------------------------- Simplified A 5::::1:: pos.-specific C ::::9::6 probability G 53aa::74 matrix T :7::193: bits 2.1 ** 1.9 ** 1.7 ** 1.5 **** Relative 1.3 **** Entropy 1.1 ****** (10.8 bits) 0.8 ******** 0.6 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel GTGGCTGC consensus AG TG sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif RTGGCTGS MEME-3 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr7:148600710-148600790 24 1.00e-05 tggttgcaag gtggctgc tgtagttcca chr19:5991399-5991479 34 1.00e-05 gaggtccact gtggctgc cgtgctccag chr19:17635585-17635665 34 1.00e-05 atggcccaag gtggctgc ttgtgctcca chr3:13307139-13307219 37 1.00e-05 acaatccaaa gtggctgc ctaagcccca chr11:64094936-64095016 33 1.00e-05 atgatccact gtggctgc ttgagttcca chr21:45357337-45357417 35 1.00e-05 AGGTGACATC GTGGCTGC CTCTGCACCA chr16:84884475-84884555 39 2.23e-05 tggtcccaag atggctgc acagcaccaa chr16:85151775-85151855 9 2.23e-05 ggtccaaa atggctgc tggaactcca chr7:100497218-100497298 15 2.23e-05 atggcataga atggctgc tggaacatca chr3:58147485-58147565 42 2.23e-05 tggtggcagg atggctgc agcagcacca chr4:2433877-2433957 33 2.23e-05 tagtcactaa atggctgc cctacctcca chr19:45270716-45270796 10 2.23e-05 tggtccaaa atggctgc tccagctccc chr1:22140232-22140312 37 2.23e-05 tctttgcaaa atggctgc tgcagctctg chr9:131962687-131962767 41 2.23e-05 tggtcacaag atggctgc ggcacctccg chr19:5325108-5325188 59 2.23e-05 atggtccaaa atggctgc ctgagcacct chr21:43780581-43780661 33 2.23e-05 TTATTACATA ATGGCTGC CTGCAACACC chr7:1754578-1754658 35 2.23e-05 tggcctcagg atggctgc cacacctctg chr21:45344527-45344607 34 2.23e-05 tggtctcgag atggctgc cttgccccgg chr1:11125167-11125247 43 4.37e-05 tgagaatgta atggctgg agcaagggca chr5:173309827-173309907 27 4.37e-05 tgcagacatg atggctgg agcttgatca chr19:5453181-5453261 21 4.37e-05 ggcagatgtg atggctgg agctcacgca chr20:60808917-60808997 41 4.37e-05 tatgcttgtg atggctgg agcatcagca chr9:140188963-140189043 25 4.37e-05 tgcagatgtg atggctgg atctggggtg chr11:60931369-60931449 20 4.37e-05 catggacatg atggctgg agcaagtgta chr7:4659483-4659563 33 4.37e-05 tatggatgtg atggctgg tgctgcagca chr19:2648757-2648837 34 5.28e-05 GCATGCCCAC GGGGCTGC AGGAGGCCCA chr1:12275776-12275856 6 6.40e-05 atggc gtggcttc agggaaagat chr16:85396208-85396288 26 7.50e-05 GAAGGCACTG agggctgc catgcaaggc chr19:11455379-11455459 10 7.50e-05 GGGATAGAc agggctgc tggggactgt chr5:175789039-175789119 51 7.50e-05 AGGCTCAAAA AGGGCTGC CAAGTGCGAG chr21:36396518-36396598 27 9.73e-05 tgtgatgttg ggggctgg agcacccatt chr5:34915073-34915153 71 9.73e-05 GAGgtggaaa ggggctgg ga chr7:67128758-67128838 50 1.08e-04 aacacaaaag gtggcttg atggttaaga chr2:170696379-170696459 35 1.08e-04 aacacgaaag gtggcttg ctggtcaaga chr12:27972599-27972679 39 1.08e-04 aacgtgaagg gtggcttg ccagttcaca chr19:56485505-56485585 37 1.08e-04 aacacaaaag gtggcttg acagttaagg chr2:54285755-54285835 29 1.08e-04 aacacaaaat gtggcttg gcagttaaga chr19:44151969-44152049 40 1.08e-04 aacatgaaat gtggcttg acggtgaagg chr7:25235880-25235960 44 1.08e-04 aacacaaaag gtggcttg gcagttaagg chr12:124312820-12431290 44 1.08e-04 aacacaaaag gtggcttg ccagtcaaaa chr1:207601336-207601416 41 1.08e-04 tacatgaaag gtggcttg acagttaagg chr19:16055395-16055475 13 1.32e-04 aacacgaaac atggcttg gcagttaaag chr5:139990644-139990724 53 1.42e-04 aaacctgaga ggggcttc taaccaagtt chr5:170253295-170253375 70 1.42e-04 aaccctgaga ggggcttc tgg chr7:71601964-71602044 57 1.42e-04 aaacctgaga ggggcttc tggccaagtt chr19:39449070-39449150 71 1.42e-04 aagcctgaga ggggcttc tg chr6:57404355-57404435 68 1.42e-04 aaacctgagt ggggcttc tggcc chr2:7020366-7020446 59 1.42e-04 aaacctgaga ggggcttc tggctgagtt chr11:62614312-62614392 69 1.42e-04 aaacctgaga ggggcttc tgtc chr20:49916866-49916946 61 1.42e-04 aaacctgaga ggggcttc tggccgattt chr2:10338784-10338864 63 1.42e-04 aaacctgaga ggggcttc tggccgattg chr2:228187424-228187504 72 1.42e-04 aaacctgaga ggggcttc t chr7:73632786-73632866 29 1.88e-04 atggtccaag atggcagc tggggtgccg chr17:961813-961893 45 1.88e-04 AGCTGGAGCC ATGGCAGC CTCCTCAGGA chr7:635485-635565 26 1.88e-04 ctggcccaac atggcagc tggagcacca chr16:30124261-30124341 50 1.88e-04 acaccctcac atggcagc cTGGGCAGGG chr6:30654128-30654208 63 2.11e-04 AGAGAGAAAT GTGGCAGG GGTGAGGGGA chr6:43866252-43866332 16 2.24e-04 tgcaaatgtg atggcagg agctgtagca chr6:35676527-35676607 51 2.24e-04 tgcagatgta atggcagg agctcagaca chrX:2526183-2526263 28 2.46e-04 ctgcttcgaa ctggctgc tgggactcca chr9:129699882-129699962 34 2.81e-04 ctgacccagt gtggttgc ttgagctcca chr7:64869076-64869156 51 2.81e-04 ctctggatcc atggctga gtgtcacacc chr9:132617808-132617888 15 2.81e-04 tgagtccaag gtggttgc ttcagctcct chr7:6388788-6388868 63 3.38e-04 acatttaaaa atggttGC AGTAggccaa chr16:11254668-11254748 31 3.38e-04 ctcatagctc agggcagc tgctggagtt chr6:27182739-27182819 19 3.85e-04 tcaagaggct ggggcagg agaatcgctt chr17:65990196-65990276 71 3.85e-04 gGCCGCTAGT GGGGCAGG GG chr19:17782915-17782995 14 3.85e-04 gcacctttcg gtggttgg aatgaagatg chr15:75434985-75435065 1 3.85e-04 . atgggtgc aagtgtgacc chr1:26042455-26042535 34 4.40e-04 aattgctgct gtggctcc agtcatcgtg chr4:6767580-6767660 32 4.40e-04 tgaagatatt atggttgg tgctccagca chr2:6985640-6985720 49 4.40e-04 aggagccagt agggcagg actagtcatg chr7:152160587-152160667 38 4.86e-04 CAAGAGCGCT CGGGCTGC CGAAACGGGA chr3:167436486-167436566 28 4.86e-04 ttaggatgtg atgggtgg ctcttcagca chr21:38751256-38751336 34 4.86e-04 CATGTGGGCA ATGGGTGG TGGTGGGAAA chr12:116803030-11680311 60 4.86e-04 tttaaagaat ggggctga ctcacctgag chr11:67204070-67204150 60 4.86e-04 tcccctcccc cgggctgc atggcctgct chr19:4233550-4233630 44 5.23e-04 acagccctcc atggctcc cacctgcctt chr19:6538032-6538112 28 5.23e-04 aacatgaaag gtggctta acagtcaagg chr3:139808701-139808781 33 6.13e-04 aacacaaaac atggctta acagttaaag chr10:74397398-74397478 25 7.92e-04 gtcattggat gtgggttg ccacaaaaaa chr5:180645580-180645660 16 9.19e-04 ttgggaggcc gaggctgg cggatcacga chr15:66981104-66981184 42 1.04e-03 gtgagccacc gtgcctgg tccagtgtat -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif RTGGCTGS MEME-3 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr7:148600710-148600790 1e-05 23_[+3]_49 chr19:5991399-5991479 1e-05 33_[+3]_39 chr19:17635585-17635665 1e-05 33_[+3]_39 chr3:13307139-13307219 1e-05 36_[+3]_36 chr11:64094936-64095016 1e-05 32_[+3]_40 chr21:45357337-45357417 1e-05 34_[+3]_38 chr16:84884475-84884555 2.2e-05 38_[+3]_34 chr16:85151775-85151855 2.2e-05 8_[+3]_64 chr7:100497218-100497298 2.2e-05 14_[+3]_58 chr3:58147485-58147565 2.2e-05 41_[+3]_31 chr4:2433877-2433957 2.2e-05 32_[+3]_40 chr19:45270716-45270796 2.2e-05 9_[+3]_63 chr1:22140232-22140312 2.2e-05 36_[+3]_36 chr9:131962687-131962767 2.2e-05 40_[+3]_32 chr19:5325108-5325188 2.2e-05 58_[+3]_14 chr21:43780581-43780661 2.2e-05 32_[+3]_40 chr7:1754578-1754658 2.2e-05 34_[+3]_38 chr21:45344527-45344607 2.2e-05 33_[+3]_39 chr1:11125167-11125247 4.4e-05 42_[+3]_30 chr5:173309827-173309907 4.4e-05 26_[+3]_46 chr19:5453181-5453261 4.4e-05 20_[+3]_52 chr20:60808917-60808997 4.4e-05 40_[+3]_32 chr9:140188963-140189043 4.4e-05 24_[+3]_48 chr11:60931369-60931449 4.4e-05 19_[+3]_53 chr7:4659483-4659563 4.4e-05 32_[+3]_40 chr19:2648757-2648837 5.3e-05 33_[+3]_39 chr1:12275776-12275856 6.4e-05 5_[+3]_67 chr16:85396208-85396288 7.5e-05 25_[+3]_47 chr19:11455379-11455459 7.5e-05 9_[+3]_63 chr5:175789039-175789119 7.5e-05 50_[+3]_22 chr21:36396518-36396598 9.7e-05 26_[+3]_46 chr5:34915073-34915153 9.7e-05 70_[+3]_2 chr7:67128758-67128838 0.00011 49_[+3]_23 chr2:170696379-170696459 0.00011 34_[+3]_38 chr12:27972599-27972679 0.00011 38_[+3]_34 chr19:56485505-56485585 0.00011 36_[+3]_36 chr2:54285755-54285835 0.00011 28_[+3]_44 chr19:44151969-44152049 0.00011 39_[+3]_33 chr7:25235880-25235960 0.00011 43_[+3]_29 chr12:124312820-12431290 0.00011 43_[+3]_29 chr1:207601336-207601416 0.00011 40_[+3]_32 chr19:16055395-16055475 0.00013 12_[+3]_60 chr5:139990644-139990724 0.00014 52_[+3]_20 chr5:170253295-170253375 0.00014 69_[+3]_3 chr7:71601964-71602044 0.00014 56_[+3]_16 chr19:39449070-39449150 0.00014 70_[+3]_2 chr6:57404355-57404435 0.00014 67_[+3]_5 chr2:7020366-7020446 0.00014 58_[+3]_14 chr11:62614312-62614392 0.00014 68_[+3]_4 chr20:49916866-49916946 0.00014 60_[+3]_12 chr2:10338784-10338864 0.00014 62_[+3]_10 chr2:228187424-228187504 0.00014 71_[+3]_1 chr7:73632786-73632866 0.00019 28_[+3]_44 chr17:961813-961893 0.00019 44_[+3]_28 chr7:635485-635565 0.00019 25_[+3]_47 chr16:30124261-30124341 0.00019 49_[+3]_23 chr6:30654128-30654208 0.00021 62_[+3]_10 chr6:43866252-43866332 0.00022 15_[+3]_57 chr6:35676527-35676607 0.00022 50_[+3]_22 chrX:2526183-2526263 0.00025 27_[+3]_45 chr9:129699882-129699962 0.00028 33_[+3]_39 chr7:64869076-64869156 0.00028 50_[+3]_22 chr9:132617808-132617888 0.00028 14_[+3]_58 chr7:6388788-6388868 0.00034 62_[+3]_10 chr16:11254668-11254748 0.00034 30_[+3]_42 chr6:27182739-27182819 0.00038 18_[+3]_54 chr17:65990196-65990276 0.00038 70_[+3]_2 chr19:17782915-17782995 0.00038 13_[+3]_59 chr15:75434985-75435065 0.00038 [+3]_72 chr1:26042455-26042535 0.00044 33_[+3]_39 chr4:6767580-6767660 0.00044 31_[+3]_41 chr2:6985640-6985720 0.00044 48_[+3]_24 chr7:152160587-152160667 0.00049 37_[+3]_35 chr3:167436486-167436566 0.00049 27_[+3]_45 chr21:38751256-38751336 0.00049 33_[+3]_39 chr12:116803030-11680311 0.00049 59_[+3]_13 chr11:67204070-67204150 0.00049 59_[+3]_13 chr19:4233550-4233630 0.00052 43_[+3]_29 chr19:6538032-6538112 0.00052 27_[+3]_45 chr3:139808701-139808781 0.00061 32_[+3]_40 chr10:74397398-74397478 0.00079 24_[+3]_48 chr5:180645580-180645660 0.00092 15_[+3]_57 chr15:66981104-66981184 0.001 41_[+3]_31 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif RTGGCTGS MEME-3 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF RTGGCTGS width=8 seqs=83 chr7:148600710-148600790 ( 24) GTGGCTGC 1 chr19:5991399-5991479 ( 34) GTGGCTGC 1 chr19:17635585-17635665 ( 34) GTGGCTGC 1 chr3:13307139-13307219 ( 37) GTGGCTGC 1 chr11:64094936-64095016 ( 33) GTGGCTGC 1 chr21:45357337-45357417 ( 35) GTGGCTGC 1 chr16:84884475-84884555 ( 39) ATGGCTGC 1 chr16:85151775-85151855 ( 9) ATGGCTGC 1 chr7:100497218-100497298 ( 15) ATGGCTGC 1 chr3:58147485-58147565 ( 42) ATGGCTGC 1 chr4:2433877-2433957 ( 33) ATGGCTGC 1 chr19:45270716-45270796 ( 10) ATGGCTGC 1 chr1:22140232-22140312 ( 37) ATGGCTGC 1 chr9:131962687-131962767 ( 41) ATGGCTGC 1 chr19:5325108-5325188 ( 59) ATGGCTGC 1 chr21:43780581-43780661 ( 33) ATGGCTGC 1 chr7:1754578-1754658 ( 35) ATGGCTGC 1 chr21:45344527-45344607 ( 34) ATGGCTGC 1 chr1:11125167-11125247 ( 43) ATGGCTGG 1 chr5:173309827-173309907 ( 27) ATGGCTGG 1 chr19:5453181-5453261 ( 21) ATGGCTGG 1 chr20:60808917-60808997 ( 41) ATGGCTGG 1 chr9:140188963-140189043 ( 25) ATGGCTGG 1 chr11:60931369-60931449 ( 20) ATGGCTGG 1 chr7:4659483-4659563 ( 33) ATGGCTGG 1 chr19:2648757-2648837 ( 34) GGGGCTGC 1 chr1:12275776-12275856 ( 6) GTGGCTTC 1 chr16:85396208-85396288 ( 26) AGGGCTGC 1 chr19:11455379-11455459 ( 10) AGGGCTGC 1 chr5:175789039-175789119 ( 51) AGGGCTGC 1 chr21:36396518-36396598 ( 27) GGGGCTGG 1 chr5:34915073-34915153 ( 71) GGGGCTGG 1 chr7:67128758-67128838 ( 50) GTGGCTTG 1 chr2:170696379-170696459 ( 35) GTGGCTTG 1 chr12:27972599-27972679 ( 39) GTGGCTTG 1 chr19:56485505-56485585 ( 37) GTGGCTTG 1 chr2:54285755-54285835 ( 29) GTGGCTTG 1 chr19:44151969-44152049 ( 40) GTGGCTTG 1 chr7:25235880-25235960 ( 44) GTGGCTTG 1 chr12:124312820-12431290 ( 44) GTGGCTTG 1 chr1:207601336-207601416 ( 41) GTGGCTTG 1 chr19:16055395-16055475 ( 13) ATGGCTTG 1 chr5:139990644-139990724 ( 53) GGGGCTTC 1 chr5:170253295-170253375 ( 70) GGGGCTTC 1 chr7:71601964-71602044 ( 57) GGGGCTTC 1 chr19:39449070-39449150 ( 71) GGGGCTTC 1 chr6:57404355-57404435 ( 68) GGGGCTTC 1 chr2:7020366-7020446 ( 59) GGGGCTTC 1 chr11:62614312-62614392 ( 69) GGGGCTTC 1 chr20:49916866-49916946 ( 61) GGGGCTTC 1 chr2:10338784-10338864 ( 63) GGGGCTTC 1 chr2:228187424-228187504 ( 72) GGGGCTTC 1 chr7:73632786-73632866 ( 29) ATGGCAGC 1 chr17:961813-961893 ( 45) ATGGCAGC 1 chr7:635485-635565 ( 26) ATGGCAGC 1 chr16:30124261-30124341 ( 50) ATGGCAGC 1 chr6:30654128-30654208 ( 63) GTGGCAGG 1 chr6:43866252-43866332 ( 16) ATGGCAGG 1 chr6:35676527-35676607 ( 51) ATGGCAGG 1 chrX:2526183-2526263 ( 28) CTGGCTGC 1 chr9:129699882-129699962 ( 34) GTGGTTGC 1 chr7:64869076-64869156 ( 51) ATGGCTGA 1 chr9:132617808-132617888 ( 15) GTGGTTGC 1 chr7:6388788-6388868 ( 63) ATGGTTGC 1 chr16:11254668-11254748 ( 31) AGGGCAGC 1 chr6:27182739-27182819 ( 19) GGGGCAGG 1 chr17:65990196-65990276 ( 71) GGGGCAGG 1 chr19:17782915-17782995 ( 14) GTGGTTGG 1 chr15:75434985-75435065 ( 1) ATGGGTGC 1 chr1:26042455-26042535 ( 34) GTGGCTCC 1 chr4:6767580-6767660 ( 32) ATGGTTGG 1 chr2:6985640-6985720 ( 49) AGGGCAGG 1 chr7:152160587-152160667 ( 38) CGGGCTGC 1 chr3:167436486-167436566 ( 28) ATGGGTGG 1 chr21:38751256-38751336 ( 34) ATGGGTGG 1 chr12:116803030-11680311 ( 60) GGGGCTGA 1 chr11:67204070-67204150 ( 60) CGGGCTGC 1 chr19:4233550-4233630 ( 44) ATGGCTCC 1 chr19:6538032-6538112 ( 28) GTGGCTTA 1 chr3:139808701-139808781 ( 33) ATGGCTTA 1 chr10:74397398-74397478 ( 25) GTGGGTTG 1 chr5:180645580-180645660 ( 16) GAGGCTGG 1 chr15:66981104-66981184 ( 42) GTGCCTGG 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif RTGGCTGS MEME-3 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 8.06703 E= 4.6e-028 75 -272 111 -1302 -453 -1302 27 148 -1302 -1302 212 -1302 -1302 -430 211 -1302 -1302 191 -225 -208 -107 -1302 -1302 177 -1302 -330 158 19 -253 125 75 -1302 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif RTGGCTGS MEME-3 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 83 E= 4.6e-028 0.469880 0.036145 0.493976 0.000000 0.012048 0.000000 0.277108 0.710843 0.000000 0.000000 1.000000 0.000000 0.000000 0.012048 0.987952 0.000000 0.000000 0.891566 0.048193 0.060241 0.132530 0.000000 0.000000 0.867470 0.000000 0.024096 0.686747 0.289157 0.048193 0.566265 0.385542 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif RTGGCTGS MEME-3 regular expression -------------------------------------------------------------------------------- [GA][TG]GGCT[GT][CG] -------------------------------------------------------------------------------- Time 12.46 secs. ******************************************************************************** ******************************************************************************** MOTIF TYCAGCCA MEME-4 width = 8 sites = 43 llr = 364 E-value = 1.0e-012 ******************************************************************************** -------------------------------------------------------------------------------- Motif TYCAGCCA MEME-4 Description -------------------------------------------------------------------------------- Simplified A ::1a:::9 pos.-specific C :76:19a: probability G ::3:91:: matrix T a3:::::: bits 2.1 1.9 * * * 1.7 * ** * 1.5 * **** Relative 1.3 * ***** Entropy 1.1 ** ***** (12.2 bits) 0.8 ******** 0.6 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel TCCAGCCA consensus TG sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TYCAGCCA MEME-4 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr16:85151775-85151855 23 1.45e-05 ctgctggaac tccagcca ttgcacctac chr7:100497218-100497298 49 1.45e-05 acatctacat tccagcca gcaggaagga chr1:26042455-26042535 59 1.45e-05 gtgtccacat tccagcca gcaggaaggg chr7:2944807-2944887 35 1.45e-05 ctgctggtgc tccagcca ttgcgtctgc chr19:17639571-17639651 35 1.45e-05 ctgctggagc tccagcca ttgggtctac chr11:443639-443719 66 1.45e-05 acatccacgt tccagcca gtgggaa chr9:132617808-132617888 49 1.45e-05 acatccacat tccagcca atggtaggag chr19:17635585-17635665 48 1.45e-05 ctgcttgtgc tccagcca ttgtgtccac chr16:11254668-11254748 48 1.45e-05 ctgctggagt tccagcca ttgcatccat chr3:13307139-13307219 71 1.45e-05 acatcctcat tccagcca ac chr11:64094936-64095016 47 1.45e-05 ctgcttgagt tccagcca tcacattcat chr19:45539166-45539246 49 1.45e-05 ctgttgtagc tccagcca ttacgcccac chrX:2526183-2526263 42 1.45e-05 ctgctgggac tccagcca tcacgtcatt chr6:166708989-166709069 47 4.40e-05 tctttgactg tcgagcca cttttcgtgt chr12:63548477-63548557 45 5.89e-05 tctttgaatg ttgagcca ctttttgtgt chrX:47535781-47535861 55 5.89e-05 tccttgactg ttgagcca cctttcatgt chr1:2522837-2522917 63 5.89e-05 cctgtctctg ttgagcca ctttttgtgc chr21:36396518-36396598 45 5.89e-05 agcacccatt ttgagcca tgaggtaaat chr9:125209614-125209694 48 5.89e-05 tctttgactg ttgagcca ctttttgtgt chr9:140188963-140189043 48 5.89e-05 gggtgccatt ttgagcca tgTGAACGAA chr11:124197843-12419792 19 5.89e-05 ttgttgactg ttgagcca cactttgtat chr2:231187413-231187493 47 5.89e-05 tctttaactg ttgagcca cttttcatgt chr22:24600668-24600748 47 5.89e-05 tctttaactg ttgagcca cttttcatgt chr6:90029981-90030061 52 5.89e-05 tctttgactg ttgagcca cttttcatgt chr5:177368705-177368785 55 5.89e-05 ctgctgactg ttgagcca cccttcgtgt chr3:167436486-167436566 5 7.29e-05 ccct tccaggca acaacttagg chr1:53671903-53671983 22 7.29e-05 cacctggatg tccaggca gaagtctgct chr12:123315472-12331555 20 7.29e-05 agaagagaat tccaggca gtaggaacag chr3:45112684-45112764 60 7.29e-05 acacacacat tccaggca ggaagaagag chr7:512381-512461 50 7.29e-05 ctgccatagc tccaggca tcacgtcctc chr21:45344527-45344607 67 7.29e-05 tcatctgcat tccaggca ggaagg chr19:14844508-14844588 43 8.99e-05 gtcttaacca tcaagcca ctttttgtgt chrX:79568097-79568177 50 8.99e-05 tccttgactg tcaagcca cctttcatgt chr4:171202332-171202412 40 8.99e-05 atctttactg tcaagcca cgtttcatgt chr1:9156006-9156086 38 8.99e-05 tccttaactg tcaagcca cattttgtgt chr1:17232264-17232344 49 1.33e-04 atcctcctgt tccaccca ttggtctctc chr1:1042038-1042118 44 1.64e-04 tgaggagccc tccagccc accgctgcac chr1:165667230-165667310 5 1.77e-04 gcac tccagcct gggcgacaga chr15:75434985-75435065 19 2.22e-04 aagtgtgacc ttcaccca tgtagcaggg chr7:86957785-86957865 21 2.22e-04 aagcatgacc ttcaccca tggatctgga chr1:199928664-199928744 51 2.47e-04 tgagaagtcc ttcagccc gccgctgcac chrX:67682584-67682664 5 2.74e-04 gcac ttcagcct gggcaacaaa chr6:6881104-6881184 25 2.90e-04 gctactgagc tccagcta ccacatccac -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TYCAGCCA MEME-4 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr16:85151775-85151855 1.5e-05 22_[+4]_50 chr7:100497218-100497298 1.5e-05 48_[+4]_24 chr1:26042455-26042535 1.5e-05 58_[+4]_14 chr7:2944807-2944887 1.5e-05 34_[+4]_38 chr19:17639571-17639651 1.5e-05 34_[+4]_38 chr11:443639-443719 1.5e-05 65_[+4]_7 chr9:132617808-132617888 1.5e-05 48_[+4]_24 chr19:17635585-17635665 1.5e-05 47_[+4]_25 chr16:11254668-11254748 1.5e-05 47_[+4]_25 chr3:13307139-13307219 1.5e-05 70_[+4]_2 chr11:64094936-64095016 1.5e-05 46_[+4]_26 chr19:45539166-45539246 1.5e-05 48_[+4]_24 chrX:2526183-2526263 1.5e-05 41_[+4]_31 chr6:166708989-166709069 4.4e-05 46_[+4]_26 chr12:63548477-63548557 5.9e-05 44_[+4]_28 chrX:47535781-47535861 5.9e-05 54_[+4]_18 chr1:2522837-2522917 5.9e-05 62_[+4]_10 chr21:36396518-36396598 5.9e-05 44_[+4]_28 chr9:125209614-125209694 5.9e-05 47_[+4]_25 chr9:140188963-140189043 5.9e-05 47_[+4]_25 chr11:124197843-12419792 5.9e-05 18_[+4]_54 chr2:231187413-231187493 5.9e-05 46_[+4]_26 chr22:24600668-24600748 5.9e-05 46_[+4]_26 chr6:90029981-90030061 5.9e-05 51_[+4]_21 chr5:177368705-177368785 5.9e-05 54_[+4]_18 chr3:167436486-167436566 7.3e-05 4_[+4]_68 chr1:53671903-53671983 7.3e-05 21_[+4]_51 chr12:123315472-12331555 7.3e-05 19_[+4]_53 chr3:45112684-45112764 7.3e-05 59_[+4]_13 chr7:512381-512461 7.3e-05 49_[+4]_23 chr21:45344527-45344607 7.3e-05 66_[+4]_6 chr19:14844508-14844588 9e-05 42_[+4]_30 chrX:79568097-79568177 9e-05 49_[+4]_23 chr4:171202332-171202412 9e-05 39_[+4]_33 chr1:9156006-9156086 9e-05 37_[+4]_35 chr1:17232264-17232344 0.00013 48_[+4]_24 chr1:1042038-1042118 0.00016 43_[+4]_29 chr1:165667230-165667310 0.00018 4_[+4]_68 chr15:75434985-75435065 0.00022 18_[+4]_54 chr7:86957785-86957865 0.00022 20_[+4]_52 chr1:199928664-199928744 0.00025 50_[+4]_22 chrX:67682584-67682664 0.00027 4_[+4]_68 chr6:6881104-6881184 0.00029 24_[+4]_48 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TYCAGCCA MEME-4 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF TYCAGCCA width=8 seqs=43 chr16:85151775-85151855 ( 23) TCCAGCCA 1 chr7:100497218-100497298 ( 49) TCCAGCCA 1 chr1:26042455-26042535 ( 59) TCCAGCCA 1 chr7:2944807-2944887 ( 35) TCCAGCCA 1 chr19:17639571-17639651 ( 35) TCCAGCCA 1 chr11:443639-443719 ( 66) TCCAGCCA 1 chr9:132617808-132617888 ( 49) TCCAGCCA 1 chr19:17635585-17635665 ( 48) TCCAGCCA 1 chr16:11254668-11254748 ( 48) TCCAGCCA 1 chr3:13307139-13307219 ( 71) TCCAGCCA 1 chr11:64094936-64095016 ( 47) TCCAGCCA 1 chr19:45539166-45539246 ( 49) TCCAGCCA 1 chrX:2526183-2526263 ( 42) TCCAGCCA 1 chr6:166708989-166709069 ( 47) TCGAGCCA 1 chr12:63548477-63548557 ( 45) TTGAGCCA 1 chrX:47535781-47535861 ( 55) TTGAGCCA 1 chr1:2522837-2522917 ( 63) TTGAGCCA 1 chr21:36396518-36396598 ( 45) TTGAGCCA 1 chr9:125209614-125209694 ( 48) TTGAGCCA 1 chr9:140188963-140189043 ( 48) TTGAGCCA 1 chr11:124197843-12419792 ( 19) TTGAGCCA 1 chr2:231187413-231187493 ( 47) TTGAGCCA 1 chr22:24600668-24600748 ( 47) TTGAGCCA 1 chr6:90029981-90030061 ( 52) TTGAGCCA 1 chr5:177368705-177368785 ( 55) TTGAGCCA 1 chr3:167436486-167436566 ( 5) TCCAGGCA 1 chr1:53671903-53671983 ( 22) TCCAGGCA 1 chr12:123315472-12331555 ( 20) TCCAGGCA 1 chr3:45112684-45112764 ( 60) TCCAGGCA 1 chr7:512381-512461 ( 50) TCCAGGCA 1 chr21:45344527-45344607 ( 67) TCCAGGCA 1 chr19:14844508-14844588 ( 43) TCAAGCCA 1 chrX:79568097-79568177 ( 50) TCAAGCCA 1 chr4:171202332-171202412 ( 40) TCAAGCCA 1 chr1:9156006-9156086 ( 38) TCAAGCCA 1 chr1:17232264-17232344 ( 49) TCCACCCA 1 chr1:1042038-1042118 ( 44) TCCAGCCC 1 chr1:165667230-165667310 ( 5) TCCAGCCT 1 chr15:75434985-75435065 ( 19) TTCACCCA 1 chr7:86957785-86957865 ( 21) TTCACCCA 1 chr1:199928664-199928744 ( 51) TTCAGCCC 1 chrX:67682584-67682664 ( 5) TTCAGCCT 1 chr6:6881104-6881184 ( 25) TCCAGCTA 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TYCAGCCA MEME-4 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 8.2488 E= 1.0e-012 -1207 -1207 -1207 198 -1207 145 -1207 46 -158 140 28 -1207 184 -1207 -1207 -1207 -1207 -177 202 -1207 -1207 186 -72 -1207 -1207 204 -1207 -345 170 -235 -1207 -245 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TYCAGCCA MEME-4 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 43 E= 1.0e-012 0.000000 0.000000 0.000000 1.000000 0.000000 0.651163 0.000000 0.348837 0.093023 0.627907 0.279070 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.069767 0.930233 0.000000 0.000000 0.860465 0.139535 0.000000 0.000000 0.976744 0.000000 0.023256 0.906977 0.046512 0.000000 0.046512 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TYCAGCCA MEME-4 regular expression -------------------------------------------------------------------------------- T[CT][CG]AGCCA -------------------------------------------------------------------------------- Time 15.92 secs. ******************************************************************************** ******************************************************************************** MOTIF TTTCTTTC MEME-5 width = 8 sites = 41 llr = 347 E-value = 8.0e-011 ******************************************************************************** -------------------------------------------------------------------------------- Motif TTTCTTTC MEME-5 Description -------------------------------------------------------------------------------- Simplified A :::::::: pos.-specific C 1::a1137 probability G :::::1:: matrix T 9aa:9873 bits 2.1 * 1.9 * * 1.7 **** 1.5 ***** Relative 1.3 ****** * Entropy 1.1 ******** (12.2 bits) 0.8 ******** 0.6 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel TTTCTTTC consensus CT sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTTCTTTC MEME-5 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr11:118505372-11850545 65 1.52e-05 tttctgccct tttctttc tcctcgcc chr19:14844508-14844588 60 1.52e-05 actttttgtg tttctttc ctctttcttt chrX:47535781-47535861 72 1.52e-05 acctttcatg tttctttc c chr16:30826023-30826103 67 1.52e-05 cttccCTttc tttctttc ctttct chr9:125209614-125209694 65 1.52e-05 actttttgtg tttctttc ttctttct chrX:79568097-79568177 67 1.52e-05 acctttcatg tttctttc ctcttt chr4:171202332-171202412 57 1.52e-05 acgtttcatg tttctttc ctatttcttt chr12:93572044-93572124 53 1.52e-05 acttttcatg tttctttc ttccttattc chr11:124197843-12419792 36 1.52e-05 acactttgta tttctttc ctctttcttt chr2:231187413-231187493 64 1.52e-05 acttttcatg tttctttc ccctttctt chr6:5324360-5324440 61 1.52e-05 gccattcgtg tttctttc ctcttatttt chr20:56111501-56111581 65 1.52e-05 acctttcatg tttctttc ctctttct chr13:42844807-42844887 47 1.52e-05 gctttttgtg tttctttc tttaactctt chr6:90029981-90030061 69 1.52e-05 acttttcatg tttctttc cttt chr1:9156006-9156086 55 1.52e-05 acattttgtg tttctttc ttgtttcttt chr16:15744548-15744628 51 4.57e-05 ATGACCCTCG TTTCTTTT CTCTCTCTCT chr19:33382635-33382715 47 4.57e-05 ggagaaagaa tttctttt gctttttaaa chr10:82256456-82256536 20 4.57e-05 ttactgatct tttcttcc atactgtctc chr1:114022490-114022570 71 4.57e-05 tttctgtttg tttctttt tt chr1:118313911-118313991 6 4.57e-05 gattc tttctttt gcatgagaga chr17:57028027-57028107 17 6.09e-05 tcaaaaattt tttcttct gtttggtcta chr7:134841217-134841297 4 6.09e-05 ttc tttcttct gcttggtgta chr4:56150654-56150734 1 6.09e-05 . tttcttct gtttgatcaa chr17:38917024-38917104 13 6.09e-05 ttgctaattc tttcttct gcatgataga chr1:221915134-221915214 49 7.46e-05 CATCTCTATC TTTCTGTC TCTGTCTCTC chr1:89383188-89383268 41 8.89e-05 gtattttcta tttccttc aatgaatttt chr20:60808917-60808997 7 8.89e-05 tcctct tttccttc ctcctttctg chr22:24600668-24600748 64 8.89e-05 acttttcatg tttccttc ctctttctt chr5:177368705-177368785 72 1.03e-04 acccttcgtg tttctctc c chr20:48816382-48816462 13 1.17e-04 ccagcccctg cttctttc tacttcctgc chr9:94467836-94467916 61 1.45e-04 agctccagaa tttctgtt tgattctttt chr10:73705784-73705864 55 1.45e-04 ttctgcctaa tttctgcc tcaaaggaaa chr7:102643617-102643697 66 1.45e-04 agttccagga tttctgtt taagtgt chr1:11125167-11125247 9 1.88e-04 tgctgttc tttcctcc ttccagcaga chr16:89152380-89152460 56 2.16e-04 AAATGGGCTG TTTCTCCC GAGGCATCTC chr12:94320139-94320219 68 2.16e-04 accctttgtg tttctccc ctctt chr3:45114957-45115037 23 2.45e-04 ccccacctct cttcttcc tgcctggaat chr7:4659483-4659563 3 2.45e-04 ct cttcttcc tcctatctgg chr12:30937585-30937665 71 2.59e-04 acatttcgtg tctctttc ct chr22:21452600-21452680 37 3.01e-04 caggataatc ttcctttt gattaactca chr6:27619265-27619345 50 3.01e-04 CCCAGGTGTG TTCCTTTT GTGTGTACTG -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTTCTTTC MEME-5 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr11:118505372-11850545 1.5e-05 64_[+5]_8 chr19:14844508-14844588 1.5e-05 59_[+5]_13 chrX:47535781-47535861 1.5e-05 71_[+5]_1 chr16:30826023-30826103 1.5e-05 66_[+5]_6 chr9:125209614-125209694 1.5e-05 64_[+5]_8 chrX:79568097-79568177 1.5e-05 66_[+5]_6 chr4:171202332-171202412 1.5e-05 56_[+5]_16 chr12:93572044-93572124 1.5e-05 52_[+5]_20 chr11:124197843-12419792 1.5e-05 35_[+5]_37 chr2:231187413-231187493 1.5e-05 63_[+5]_9 chr6:5324360-5324440 1.5e-05 60_[+5]_12 chr20:56111501-56111581 1.5e-05 64_[+5]_8 chr13:42844807-42844887 1.5e-05 46_[+5]_26 chr6:90029981-90030061 1.5e-05 68_[+5]_4 chr1:9156006-9156086 1.5e-05 54_[+5]_18 chr16:15744548-15744628 4.6e-05 50_[+5]_22 chr19:33382635-33382715 4.6e-05 46_[+5]_26 chr10:82256456-82256536 4.6e-05 19_[+5]_53 chr1:114022490-114022570 4.6e-05 70_[+5]_2 chr1:118313911-118313991 4.6e-05 5_[+5]_67 chr17:57028027-57028107 6.1e-05 16_[+5]_56 chr7:134841217-134841297 6.1e-05 3_[+5]_69 chr4:56150654-56150734 6.1e-05 [+5]_72 chr17:38917024-38917104 6.1e-05 12_[+5]_60 chr1:221915134-221915214 7.5e-05 48_[+5]_24 chr1:89383188-89383268 8.9e-05 40_[+5]_32 chr20:60808917-60808997 8.9e-05 6_[+5]_66 chr22:24600668-24600748 8.9e-05 63_[+5]_9 chr5:177368705-177368785 0.0001 71_[+5]_1 chr20:48816382-48816462 0.00012 12_[+5]_60 chr9:94467836-94467916 0.00014 60_[+5]_12 chr10:73705784-73705864 0.00014 54_[+5]_18 chr7:102643617-102643697 0.00014 65_[+5]_7 chr1:11125167-11125247 0.00019 8_[+5]_64 chr16:89152380-89152460 0.00022 55_[+5]_17 chr12:94320139-94320219 0.00022 67_[+5]_5 chr3:45114957-45115037 0.00024 22_[+5]_50 chr7:4659483-4659563 0.00024 2_[+5]_70 chr12:30937585-30937665 0.00026 70_[+5]_2 chr22:21452600-21452680 0.0003 36_[+5]_36 chr6:27619265-27619345 0.0003 49_[+5]_23 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTTCTTTC MEME-5 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF TTTCTTTC width=8 seqs=41 chr11:118505372-11850545 ( 65) TTTCTTTC 1 chr19:14844508-14844588 ( 60) TTTCTTTC 1 chrX:47535781-47535861 ( 72) TTTCTTTC 1 chr16:30826023-30826103 ( 67) TTTCTTTC 1 chr9:125209614-125209694 ( 65) TTTCTTTC 1 chrX:79568097-79568177 ( 67) TTTCTTTC 1 chr4:171202332-171202412 ( 57) TTTCTTTC 1 chr12:93572044-93572124 ( 53) TTTCTTTC 1 chr11:124197843-12419792 ( 36) TTTCTTTC 1 chr2:231187413-231187493 ( 64) TTTCTTTC 1 chr6:5324360-5324440 ( 61) TTTCTTTC 1 chr20:56111501-56111581 ( 65) TTTCTTTC 1 chr13:42844807-42844887 ( 47) TTTCTTTC 1 chr6:90029981-90030061 ( 69) TTTCTTTC 1 chr1:9156006-9156086 ( 55) TTTCTTTC 1 chr16:15744548-15744628 ( 51) TTTCTTTT 1 chr19:33382635-33382715 ( 47) TTTCTTTT 1 chr10:82256456-82256536 ( 20) TTTCTTCC 1 chr1:114022490-114022570 ( 71) TTTCTTTT 1 chr1:118313911-118313991 ( 6) TTTCTTTT 1 chr17:57028027-57028107 ( 17) TTTCTTCT 1 chr7:134841217-134841297 ( 4) TTTCTTCT 1 chr4:56150654-56150734 ( 1) TTTCTTCT 1 chr17:38917024-38917104 ( 13) TTTCTTCT 1 chr1:221915134-221915214 ( 49) TTTCTGTC 1 chr1:89383188-89383268 ( 41) TTTCCTTC 1 chr20:60808917-60808997 ( 7) TTTCCTTC 1 chr22:24600668-24600748 ( 64) TTTCCTTC 1 chr5:177368705-177368785 ( 72) TTTCTCTC 1 chr20:48816382-48816462 ( 13) CTTCTTTC 1 chr9:94467836-94467916 ( 61) TTTCTGTT 1 chr10:73705784-73705864 ( 55) TTTCTGCC 1 chr7:102643617-102643697 ( 66) TTTCTGTT 1 chr1:11125167-11125247 ( 9) TTTCCTCC 1 chr16:89152380-89152460 ( 56) TTTCTCCC 1 chr12:94320139-94320219 ( 68) TTTCTCCC 1 chr3:45114957-45115037 ( 23) CTTCTTCC 1 chr7:4659483-4659563 ( 3) CTTCTTCC 1 chr12:30937585-30937665 ( 71) TCTCTTTC 1 chr22:21452600-21452680 ( 37) TTCCTTTT 1 chr6:27619265-27619345 ( 50) TTCCTTTT 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTTCTTTC MEME-5 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 9.76163 E= 8.0e-011 -1200 -170 -1200 187 -1200 -328 -1200 194 -1200 -228 -1200 190 -1200 207 -1200 -1200 -1200 -128 -1200 183 -1200 -170 -123 171 -1200 18 -1200 153 -1200 157 -1200 20 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTTCTTTC MEME-5 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 41 E= 8.0e-011 0.000000 0.073171 0.000000 0.926829 0.000000 0.024390 0.000000 0.975610 0.000000 0.048780 0.000000 0.951220 0.000000 1.000000 0.000000 0.000000 0.000000 0.097561 0.000000 0.902439 0.000000 0.073171 0.097561 0.829268 0.000000 0.268293 0.000000 0.731707 0.000000 0.707317 0.000000 0.292683 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTTCTTTC MEME-5 regular expression -------------------------------------------------------------------------------- TTTCTT[TC][CT] -------------------------------------------------------------------------------- Time 19.31 secs. ******************************************************************************** ******************************************************************************** SUMMARY OF MOTIFS ******************************************************************************** -------------------------------------------------------------------------------- Combined block diagrams: non-overlapping sites with p-value < 0.0001 -------------------------------------------------------------------------------- SEQUENCE NAME COMBINED P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr1:9156006-9156086 1.17e-06 1_[+1(4.27e-05)]_7_[+2(5.42e-05)]_\ 13_[+4(8.99e-05)]_9_[+5(1.52e-05)]_18 chr19:6538032-6538112 5.51e-05 1_[+2(7.90e-05)]_3_[+2(2.57e-05)]_\ 28_[+1(1.55e-05)]_7_[+2(5.42e-05)]_9 chr19:16055395-16055475 4.31e-04 33_[+1(3.00e-05)]_39 chr2:228187424-228187504 9.21e-05 44_[+1(1.55e-05)]_28 chr12:111210404-11121048 5.74e-05 4_[+2(7.90e-05)]_3_[+2(2.57e-05)]_\ 27_[+1(1.55e-05)]_22 chr2:10338784-10338864 7.57e-05 35_[+1(1.55e-05)]_37 chr19:6578822-6578902 2.54e-04 10_[+2(7.90e-05)]_3_[+2(2.57e-05)]_\ 28_[+1(1.55e-05)]_15 chr7:1842784-1842864 6.44e-04 10_[+2(2.57e-05)]_28_[+1(1.55e-05)]_\ 26 chr15:42317408-42317488 3.58e-03 18_[+2(7.90e-05)]_7_[+2(2.57e-05)]_\ 26_[+1(3.00e-05)]_5 chr1:207601336-207601416 4.13e-05 14_[+2(7.90e-05)]_39_[+1(1.55e-05)]_\ 11 chr12:124312820-12431290 1.91e-05 17_[+2(7.90e-05)]_3_[+2(2.57e-05)]_\ 27_[+1(1.55e-05)]_9 chr20:49916866-49916946 4.55e-04 35_[+1(3.00e-05)]_37 chr5:177368705-177368785 1.57e-04 36_[+2(5.42e-05)]_10_[+4(5.89e-05)]_\ 18 chr11:62614312-62614392 1.49e-04 [+2(2.57e-05)]_46_[+2(5.42e-05)]_18 chr6:90029981-90030061 2.51e-07 17_[+1(1.55e-05)]_5_[+2(5.42e-05)]_\ 13_[+4(5.89e-05)]_9_[+5(1.52e-05)]_4 chr7:129898505-129898585 5.33e-01 80 chr7:25235880-25235960 2.91e-06 17_[+2(7.90e-05)]_3_[+2(2.57e-05)]_\ 28_[+1(1.55e-05)]_8 chr17:47206866-47206946 2.85e-04 29_[+2(7.90e-05)]_3_[+2(2.57e-05)]_\ 24_[+1(1.55e-05)] chr21:45344527-45344607 3.06e-04 33_[+3(2.23e-05)]_25_[+4(7.29e-05)]_\ 6 chr13:42844807-42844887 1.83e-03 12_[+2(5.42e-05)]_26_[+5(1.52e-05)]_\ 26 chr19:44151969-44152049 1.81e-05 24_[+2(2.57e-05)]_28_[+1(1.55e-05)]_\ 12 chr1:241805477-241805557 7.99e-02 35_[+2(7.90e-05)]_3_[+2(2.57e-05)]_\ 26 chrX:2526183-2526263 1.10e-03 41_[+4(1.45e-05)]_31 chr2:7020366-7020446 9.51e-05 29_[+1(1.55e-05)]_43 chr1:118241222-118241302 6.02e-01 80 chr1:118313911-118313991 2.62e-02 5_[+5(4.57e-05)]_67 chr20:56111501-56111581 6.21e-04 12_[+1(4.27e-05)]_44_[+5(1.52e-05)]_\ 8 chr1:16003873-16003953 1.56e-02 80 chr2:234159374-234159454 6.87e-04 10_[+2(2.57e-05)]_28_[+1(1.55e-05)]_\ 26 chr22:24600668-24600748 2.96e-06 12_[+1(1.55e-05)]_26_[+4(5.89e-05)]_\ 9_[+5(8.89e-05)]_9 chr12:30937585-30937665 1.03e-02 80 chr6:166708989-166709069 2.48e-06 12_[+1(1.55e-05)]_5_[+2(5.42e-05)]_\ 13_[+4(4.40e-05)]_26 chr6:5324360-5324440 3.50e-03 60_[+5(1.52e-05)]_12 chr7:1754578-1754658 4.45e-02 34_[+3(2.23e-05)]_38 chr2:231187413-231187493 2.51e-07 12_[+1(1.55e-05)]_5_[+2(5.42e-05)]_\ 13_[+4(5.89e-05)]_9_[+5(1.52e-05)]_9 chr1:1042038-1042118 6.48e-02 80 chr10:45782587-45782667 1.93e-04 4_[+2(2.57e-05)]_28_[+1(1.55e-05)]_\ 32 chr21:45357337-45357417 2.08e-02 34_[+3(1.00e-05)]_38 chr21:43780581-43780661 9.85e-02 32_[+3(2.23e-05)]_40 chr10:45769964-45770044 1.58e-03 5_[+2(7.90e-05)]_38_[+1(1.55e-05)]_\ 21 chr11:74577724-74577804 9.80e-01 80 chr1:247409763-247409843 8.21e-01 80 chr9:139588148-139588228 4.24e-01 80 chr1:17232264-17232344 3.51e-02 80 chr6:16040971-16041051 4.90e-01 80 chr11:124197843-12419792 3.76e-03 18_[+4(5.89e-05)]_9_[+5(1.52e-05)]_\ 37 chr6:57404355-57404435 1.61e-05 4_[+2(2.57e-05)]_28_[+1(1.55e-05)]_\ 32 chr19:39449070-39449150 1.06e-04 7_[+2(2.57e-05)]_28_[+1(7.60e-05)]_\ 29 chr7:4659483-4659563 6.99e-03 32_[+3(4.37e-05)]_40 chr12:93572044-93572124 8.99e-06 1_[+1(1.55e-05)]_5_[+2(5.42e-05)]_\ 30_[+5(1.52e-05)]_20 chr19:1935663-1935743 2.41e-01 80 chr19:2648757-2648837 1.64e-02 33_[+3(5.28e-05)]_39 chr19:13388032-13388112 8.60e-02 80 chr2:54285755-54285835 2.06e-05 2_[+2(7.90e-05)]_3_[+2(2.57e-05)]_\ 27_[+1(3.00e-05)]_24 chr5:34915073-34915153 2.03e-01 70_[+3(9.73e-05)]_2 chr12:94320139-94320219 1.16e-04 16_[+1(1.55e-05)]_2_[+2(5.42e-05)]_\ 46 chr7:512381-512461 1.80e-01 49_[+4(7.29e-05)]_23 chr4:171202332-171202412 5.94e-05 19_[+2(5.42e-05)]_12_[+4(8.99e-05)]_\ 9_[+5(1.52e-05)]_16 chr16:30124261-30124341 1.26e-01 80 chr6:6881104-6881184 1.51e-01 80 chr19:45539166-45539246 4.55e-02 48_[+4(1.45e-05)]_24 chr19:8139556-8139636 9.63e-01 80 chr19:56485505-56485585 1.68e-05 10_[+2(7.90e-05)]_3_[+2(2.57e-05)]_\ 28_[+1(1.55e-05)]_15 chrX:67682584-67682664 3.92e-02 80 chr11:64094936-64095016 7.52e-04 32_[+3(1.00e-05)]_6_[+4(1.45e-05)]_\ 26 chr7:3005558-3005638 9.51e-01 80 chr3:13307139-13307219 9.75e-04 36_[+3(1.00e-05)]_26_[+4(1.45e-05)]_\ 2 chr4:25225527-25225607 9.34e-02 28_[+1(6.15e-05)]_44 chr3:45112684-45112764 1.32e-01 59_[+4(7.29e-05)]_13 chr1:16832994-16833074 7.33e-02 24_[+1(6.15e-05)]_48 chr3:73194147-73194227 2.07e-01 80 chr13:41722988-41723068 8.85e-02 80 chrX:79568097-79568177 6.24e-07 13_[+1(4.27e-05)]_7_[+2(5.42e-05)]_\ 13_[+4(8.99e-05)]_9_[+5(1.52e-05)]_6 chr16:11254668-11254748 1.05e-02 47_[+4(1.45e-05)]_25 chr19:17635585-17635665 5.13e-04 33_[+3(1.00e-05)]_6_[+4(1.45e-05)]_\ 25 chr11:60931369-60931449 8.03e-02 19_[+3(4.37e-05)]_53 chr7:86957785-86957865 2.64e-01 80 chr17:47199231-47199311 1.74e-04 4_[+2(7.90e-05)]_3_[+2(2.57e-05)]_\ 28_[+1(1.55e-05)]_21 chr9:140188963-140189043 4.33e-03 24_[+3(4.37e-05)]_15_[+4(5.89e-05)]_\ 25 chr9:125209614-125209694 2.51e-07 13_[+1(1.55e-05)]_5_[+2(5.42e-05)]_\ 13_[+4(5.89e-05)]_9_[+5(1.52e-05)]_8 chr21:36396518-36396598 4.21e-03 26_[+3(9.73e-05)]_10_[+4(5.89e-05)]_\ 28 chr7:102643617-102643697 1.41e-01 80 chr17:38917024-38917104 1.11e-01 12_[+5(6.09e-05)]_60 chr22:19324830-19324910 5.78e-01 80 chr12:752552-752632 6.64e-01 80 chr19:5325108-5325188 1.79e-02 58_[+3(2.23e-05)]_14 chr4:56150654-56150734 6.57e-02 [+5(6.09e-05)]_72 chr11:67204070-67204150 4.49e-02 80 chr3:45114957-45115037 1.18e-01 80 chr18:77782838-77782918 3.85e-01 80 chr9:132617808-132617888 4.07e-04 48_[+4(1.45e-05)]_24 chr10:73537145-73537225 4.09e-01 80 chr1:2522837-2522917 6.62e-06 33_[+1(1.55e-05)]_4_[+2(5.42e-05)]_\ 9_[+4(5.89e-05)]_10 chr15:75434985-75435065 5.34e-02 80 chr1:112290058-112290138 1.08e-01 80 chr6:35676527-35676607 7.11e-02 80 chr1:114022490-114022570 7.41e-02 70_[+5(4.57e-05)]_2 chr1:233697733-233697813 1.98e-01 80 chr16:11301658-11301738 1.97e-01 80 chr9:131962687-131962767 6.87e-02 40_[+3(2.23e-05)]_32 chr21:45864650-45864730 7.18e-01 80 chr1:22140232-22140312 1.01e-01 36_[+3(2.23e-05)]_36 chr6:28756837-28756917 1.21e-01 80 chr10:58130633-58130713 5.54e-01 80 chr21:39601347-39601427 4.53e-01 80 chr19:6292194-6292274 4.00e-01 80 chr8:42979673-42979753 5.86e-01 80 chr20:60808917-60808997 1.44e-03 6_[+5(8.89e-05)]_26_[+3(4.37e-05)]_\ 32 chr19:5991399-5991479 6.44e-04 33_[+3(1.00e-05)]_5_[+4(1.45e-05)]_\ 12_[+4(1.45e-05)]_6 chr19:17782915-17782995 3.01e-01 80 chr7:134841217-134841297 6.33e-03 3_[+5(6.09e-05)]_43_[+5(8.89e-05)]_\ 18 chr2:6985640-6985720 4.76e-02 80 chr11:443639-443719 1.73e-02 65_[+4(1.45e-05)]_7 chr22:19139213-19139293 5.31e-01 80 chr1:89383188-89383268 1.87e-01 40_[+5(8.89e-05)]_32 chr5:175789039-175789119 5.43e-02 50_[+3(7.50e-05)]_22 chr3:183371144-183371224 6.14e-01 80 chr19:45270716-45270796 1.58e-03 9_[+3(2.23e-05)]_63 chr16:81792240-81792320 4.09e-01 80 chr7:6388788-6388868 5.72e-02 80 chr3:47575731-47575811 7.11e-01 80 chr10:73705784-73705864 2.88e-02 80 chr15:68196212-68196292 1.17e-03 19_[+2(2.57e-05)]_27_[+1(3.00e-05)]_\ 18 chr19:11455379-11455459 1.45e-01 9_[+3(7.50e-05)]_63 chr9:94467836-94467916 4.49e-02 80 chr1:15133402-15133482 6.89e-01 80 chr4:38300633-38300713 5.47e-01 80 chr7:635485-635565 1.63e-01 80 chr3:128578532-128578612 7.32e-01 80 chr7:64869076-64869156 2.04e-01 80 chr4:2433877-2433957 4.11e-02 32_[+3(2.23e-05)]_40 chr4:6767580-6767660 3.14e-01 80 chr16:30826023-30826103 1.11e-03 24_[+5(8.89e-05)]_30_[+5(1.52e-05)]_\ 10 chr22:23339495-23339575 8.89e-01 80 chr17:39607705-39607785 1.07e-05 24_[+1(1.55e-05)]_5_[+2(5.42e-05)]_\ 13_[+4(5.89e-05)]_14 chr7:149226346-149226426 3.67e-01 80 chr6:43866252-43866332 3.25e-01 80 chr19:5453181-5453261 5.23e-02 20_[+3(4.37e-05)]_52 chr16:89152380-89152460 3.06e-02 80 chr19:17639571-17639651 5.06e-02 34_[+4(1.45e-05)]_38 chr16:11704511-11704591 2.64e-01 80 chr19:38653472-38653552 1.25e-02 80 chr10:82256456-82256536 1.36e-02 19_[+5(4.57e-05)]_53 chr11:64013432-64013512 5.19e-01 80 chr12:123315472-12331555 8.12e-02 19_[+4(7.29e-05)]_53 chr8:607156-607236 6.57e-04 13_[+2(2.57e-05)]_28_[+1(1.55e-05)]_\ 23 chr6:109657585-109657665 3.07e-02 80 chrX:47535781-47535861 4.37e-07 18_[+1(4.27e-05)]_7_[+2(5.42e-05)]_\ 13_[+4(5.89e-05)]_9_[+5(1.52e-05)]_1 chr20:1168309-1168389 5.23e-01 80 chr19:14844508-14844588 3.92e-06 22_[+2(5.42e-05)]_12_[+4(8.99e-05)]_\ 9_[+5(1.52e-05)]_13 chr5:173309827-173309907 4.07e-02 26_[+3(4.37e-05)]_46 chr4:190842393-190842473 6.94e-02 80 chr12:27972599-27972679 5.18e-05 12_[+2(7.90e-05)]_42_[+1(1.55e-05)]_\ 10 chr2:170696379-170696459 1.93e-05 8_[+2(7.90e-05)]_3_[+2(2.57e-05)]_\ 27_[+1(6.15e-05)]_18 chr7:148600710-148600790 2.41e-03 23_[+3(1.00e-05)]_49 chr7:150000279-150000359 2.87e-01 80 chr1:12623048-12623128 9.15e-01 80 chr7:2944807-2944887 4.59e-02 34_[+4(1.45e-05)]_38 chr17:21135504-21135584 3.83e-01 80 chr6:14264263-14264343 9.25e-01 80 chr17:57028027-57028107 1.43e-01 16_[+5(6.09e-05)]_56 chr12:116803030-11680311 9.32e-03 80 chr1:26042455-26042535 4.58e-03 58_[+4(1.45e-05)]_14 chr1:20344426-20344506 2.61e-01 80 chr6:42679806-42679886 1.44e-01 80 chr3:58147485-58147565 7.87e-03 41_[+3(2.23e-05)]_31 chr1:165667230-165667310 3.11e-02 80 chr12:112204235-11220431 4.61e-01 80 chr1:12275776-12275856 4.95e-03 5_[+3(6.40e-05)]_67 chr6:13795380-13795460 4.22e-01 80 chr15:66981104-66981184 1.79e-01 80 chr7:71601964-71602044 6.77e-05 27_[+1(1.55e-05)]_45 chr19:33382635-33382715 3.59e-02 46_[+5(4.57e-05)]_26 chr6:27619265-27619345 1.19e-02 80 chr2:103417745-103417825 3.93e-01 80 chr5:170253295-170253375 2.38e-04 41_[+1(1.55e-05)]_31 chr10:87571316-87571396 8.21e-02 46_[+2(7.90e-05)]_26 chr11:118505372-11850545 5.34e-02 64_[+5(1.52e-05)]_8 chr1:162446583-162446663 8.25e-01 80 chr17:961813-961893 1.62e-01 80 chr6:44027521-44027601 5.61e-02 80 chr19:45218148-45218228 6.55e-01 80 chr7:67128758-67128838 4.75e-05 34_[+2(2.57e-05)]_27_[+1(7.60e-05)]_\ 3 chr19:41331548-41331628 9.73e-01 80 chr3:139808701-139808781 8.76e-05 6_[+2(7.90e-05)]_3_[+2(2.57e-05)]_\ 28_[+1(1.55e-05)]_19 chr6:27511942-27512022 6.47e-01 80 chr17:65990196-65990276 5.92e-01 80 chr19:1795784-1795864 8.40e-01 80 chr4:128670246-128670326 7.57e-01 80 chr7:100497218-100497298 1.87e-03 14_[+3(2.23e-05)]_26_[+4(1.45e-05)]_\ 24 chr7:73632786-73632866 4.20e-01 80 chr6:26322678-26322758 9.42e-01 80 chr21:38751256-38751336 4.02e-01 80 chr3:14162293-14162373 2.85e-04 59_[+1(1.55e-05)]_13 chr22:21452600-21452680 2.72e-02 80 chr11:70079298-70079378 7.78e-02 80 chr1:229922905-229922985 7.70e-04 [+2(7.90e-05)]_3_[+2(2.57e-05)]_28_\ [+1(1.55e-05)]_25 chr21:16018170-16018250 5.43e-01 80 chr12:63548477-63548557 1.26e-05 10_[+1(1.55e-05)]_5_[+2(5.42e-05)]_\ 13_[+4(5.89e-05)]_28 chr19:4811945-4812025 5.84e-01 80 chr22:19304394-19304474 6.27e-01 80 chr5:139990644-139990724 2.51e-04 25_[+1(1.55e-05)]_47 chr20:48816382-48816462 6.40e-02 80 chr10:74397398-74397478 4.14e-01 80 chr19:4233550-4233630 1.72e-01 80 chr7:106256942-106257022 3.14e-01 80 chr16:85151775-85151855 1.30e-03 8_[+3(2.23e-05)]_6_[+4(1.45e-05)]_\ 50 chr19:13001400-13001480 8.17e-01 80 chr22:19152063-19152143 7.24e-01 80 chr16:15744548-15744628 1.52e-01 50_[+5(4.57e-05)]_22 chr1:221915134-221915214 2.28e-01 48_[+5(7.46e-05)]_24 chr12:9297109-9297189 1.97e-04 14_[+2(7.90e-05)]_3_[+2(2.57e-05)]_\ 28_[+1(1.55e-05)]_11 chr10:5207846-5207926 5.78e-01 80 chr1:151880040-151880120 3.05e-01 80 chr6:27182739-27182819 3.04e-01 80 chr5:180645580-180645660 3.92e-01 80 chr8:896896-896976 3.03e-01 80 chr16:53086977-53087057 5.71e-01 80 chr20:43591260-43591340 6.67e-01 80 chr9:132237421-132237501 3.96e-01 80 chr9:129699882-129699962 7.79e-02 80 chr16:84884475-84884555 1.70e-02 38_[+3(2.23e-05)]_34 chr19:35738564-35738644 5.71e-01 80 chr7:97069109-97069189 1.02e-01 33_[+1(6.15e-05)]_39 chr1:32403138-32403218 3.21e-01 80 chr1:53671903-53671983 5.76e-02 21_[+4(7.29e-05)]_51 chr6:24479522-24479602 5.45e-03 25_[+1(3.00e-05)]_47 chr2:10260143-10260223 4.35e-01 80 chr3:167436486-167436566 3.50e-02 4_[+4(7.29e-05)]_68 chr7:18121376-18121456 3.73e-01 80 chr2:174163435-174163515 7.68e-01 80 chr6:28758288-28758368 6.99e-01 80 chr6:88437862-88437942 1.29e-01 [+5(1.52e-05)]_[+5(1.52e-05)]_6_\ [+5(1.52e-05)]_[+5(8.89e-05)]_16_[+5(1.52e-05)]_[+5(6.09e-05)]_1_\ [+5(1.52e-05)]_1 chr5:122961928-122962008 5.19e-02 80 chr8:124073077-124073157 7.42e-01 80 chr1:199928664-199928744 1.43e-01 80 chr22:19804120-19804200 9.74e-01 80 chr16:85279491-85279571 8.33e-01 80 chr16:85396208-85396288 2.58e-01 25_[+3(7.50e-05)]_47 chr1:201405039-201405119 6.90e-01 80 chr22:20104407-20104487 3.16e-01 80 chr16:81611545-81611625 9.97e-01 80 chr3:194871515-194871595 9.79e-01 80 chr5:96143817-96143897 6.10e-01 80 chr7:152160587-152160667 2.92e-01 80 chr10:43876061-43876141 2.07e-01 80 chr6:30654128-30654208 1.53e-01 80 chr6:44012289-44012369 9.30e-01 80 chr1:11125167-11125247 1.02e-02 42_[+3(4.37e-05)]_30 chr6:42533270-42533350 8.27e-02 80 -------------------------------------------------------------------------------- ******************************************************************************** ******************************************************************************** Stopped because requested number of motifs (5) found. ******************************************************************************** CPU: c22n09.farnam.hpc.yale.internal ********************************************************************************