******************************************************************************** MEME - Motif discovery tool ******************************************************************************** MEME version 5.3.3 (Release date: Sun Feb 7 15:39:52 2021 -0800) For further information on how to interpret these results please access https://meme-suite.org/meme. To get a copy of the MEME Suite software please access https://meme-suite.org. ******************************************************************************** ******************************************************************************** REFERENCE ******************************************************************************** If you use this program in your research, please cite: Timothy L. Bailey and Charles Elkan, "Fitting a mixture model by expectation maximization to discover motifs in biopolymers", Proceedings of the Second International Conference on Intelligent Systems for Molecular Biology, pp. 28-36, AAAI Press, Menlo Park, California, 1994. ******************************************************************************** ******************************************************************************** TRAINING SET ******************************************************************************** PRIMARY SEQUENCES= ../result/final_prediction/K562/fasta/RankLinear0.6_40/HINFP.fasta CONTROL SEQUENCES= --none-- ALPHABET= ACGT Sequence name Weight Length Sequence name Weight Length ------------- ------ ------ ------------- ------ ------ chr19:4754410-4754490 1.0000 80 chr19:35453901-35453981 1.0000 80 chr1:94194417-94194497 1.0000 80 chr11:78316560-78316640 1.0000 80 chr17:72453431-72453511 1.0000 80 chr17:41392947-41393027 1.0000 80 chr8:23365264-23365344 1.0000 80 chr16:3181995-3182075 1.0000 80 chr11:106047619-10604769 1.0000 80 chr5:145921992-145922072 1.0000 80 chr8:11654674-11654754 1.0000 80 chr13:28404156-28404236 1.0000 80 chr22:19284516-19284596 1.0000 80 chr22:19620468-19620548 1.0000 80 chr22:20177996-20178076 1.0000 80 chr20:32777681-32777761 1.0000 80 chr7:116853135-116853215 1.0000 80 chr16:25377514-25377594 1.0000 80 chr6:150262813-150262893 1.0000 80 chr12:31771690-31771770 1.0000 80 chr5:180497157-180497237 1.0000 80 chr6:137092481-137092561 1.0000 80 chr2:145290968-145291048 1.0000 80 chr14:97230499-97230579 1.0000 80 chr9:130266400-130266480 1.0000 80 chr11:117923684-11792376 1.0000 80 chr11:44797174-44797254 1.0000 80 chr11:111956692-11195677 1.0000 80 chr18:33656451-33656531 1.0000 80 chr1:156130734-156130814 1.0000 80 chr4:138827264-138827344 1.0000 80 chr18:711522-711602 1.0000 80 chr12:83729602-83729682 1.0000 80 chr5:10539849-10539929 1.0000 80 chr9:139661103-139661183 1.0000 80 chr20:61406313-61406393 1.0000 80 chr17:17941976-17942056 1.0000 80 chr1:31121414-31121494 1.0000 80 chr2:61293674-61293754 1.0000 80 chr22:19654833-19654913 1.0000 80 chr20:45967183-45967263 1.0000 80 chr17:8030106-8030186 1.0000 80 chr10:70884723-70884803 1.0000 80 chr14:21150683-21150763 1.0000 80 chr10:46762624-46762704 1.0000 80 chr8:101804306-101804386 1.0000 80 chr10:75811921-75812001 1.0000 80 chr9:134638101-134638181 1.0000 80 chr8:80673391-80673471 1.0000 80 chr17:42706268-42706348 1.0000 80 chr6:43061687-43061767 1.0000 80 chrX:18224950-18225030 1.0000 80 chr8:24857567-24857647 1.0000 80 chr2:209100743-209100823 1.0000 80 chrX:133282436-133282516 1.0000 80 chr3:52567027-52567107 1.0000 80 chr9:127532796-127532876 1.0000 80 chr19:40037379-40037459 1.0000 80 chr8:79428398-79428478 1.0000 80 chr12:56561977-56562057 1.0000 80 chr5:150428237-150428317 1.0000 80 chr11:102256247-10225632 1.0000 80 chr2:201520820-201520900 1.0000 80 chr9:35574734-35574814 1.0000 80 chr19:7939430-7939510 1.0000 80 chr12:47475106-47475186 1.0000 80 chr19:33166405-33166485 1.0000 80 chr17:1090579-1090659 1.0000 80 chr9:136114363-136114443 1.0000 80 chr15:43806610-43806690 1.0000 80 chr16:89573979-89574059 1.0000 80 chr6:26071545-26071625 1.0000 80 chr16:85762575-85762655 1.0000 80 chr11:95998676-95998756 1.0000 80 chr22:37374198-37374278 1.0000 80 chr1:31545316-31545396 1.0000 80 chr19:51611220-51611300 1.0000 80 chr22:39151552-39151632 1.0000 80 chr11:117680117-11768019 1.0000 80 chr9:131465419-131465499 1.0000 80 chr10:81664549-81664629 1.0000 80 chrX:24483055-24483135 1.0000 80 chrX:9325965-9326045 1.0000 80 chr3:52568028-52568108 1.0000 80 chr22:30304121-30304201 1.0000 80 chr17:43129498-43129578 1.0000 80 chr21:45905313-45905393 1.0000 80 chr1:205735872-205735952 1.0000 80 chr12:51611008-51611088 1.0000 80 chr2:106286084-106286164 1.0000 80 chr19:39470683-39470763 1.0000 80 chr15:58357247-58357327 1.0000 80 chr1:47981231-47981311 1.0000 80 chr11:3663413-3663493 1.0000 80 chr17:37024583-37024663 1.0000 80 chr8:29197828-29197908 1.0000 80 chr9:102582843-102582923 1.0000 80 chr16:86794817-86794897 1.0000 80 chr22:37640310-37640390 1.0000 80 chr16:3151494-3151574 1.0000 80 chr19:1203120-1203200 1.0000 80 chr4:4997026-4997106 1.0000 80 chr12:117111634-11711171 1.0000 80 chr7:44769174-44769254 1.0000 80 chr4:1595675-1595755 1.0000 80 chr19:17420576-17420656 1.0000 80 chr21:47645252-47645332 1.0000 80 chr5:42909192-42909272 1.0000 80 chr14:38065267-38065347 1.0000 80 chr1:16843346-16843426 1.0000 80 chr17:7589421-7589501 1.0000 80 chr12:31934980-31935060 1.0000 80 chr17:75275996-75276076 1.0000 80 chr22:23145092-23145172 1.0000 80 chr17:79643123-79643203 1.0000 80 chr3:183872880-183872960 1.0000 80 chr8:101446339-101446419 1.0000 80 chr17:79375987-79376067 1.0000 80 chr17:45820293-45820373 1.0000 80 chr16:1429929-1430009 1.0000 80 chr2:219134646-219134726 1.0000 80 chr5:55386103-55386183 1.0000 80 chr8:91251826-91251906 1.0000 80 chr5:42757485-42757565 1.0000 80 chr8:142034530-142034610 1.0000 80 chr12:58160755-58160835 1.0000 80 chr13:22614966-22615046 1.0000 80 chr10:25233860-25233940 1.0000 80 chr8:145100883-145100963 1.0000 80 chr18:48650652-48650732 1.0000 80 chr17:27276555-27276635 1.0000 80 chr7:49997-50077 1.0000 80 chr19:1725440-1725520 1.0000 80 chr20:52509490-52509570 1.0000 80 chr21:21226155-21226235 1.0000 80 chr6:29945138-29945218 1.0000 80 chr19:10535017-10535097 1.0000 80 chr3:69745620-69745700 1.0000 80 chr4:1875218-1875298 1.0000 80 chr19:6862967-6863047 1.0000 80 chr20:47936099-47936179 1.0000 80 chr8:128990129-128990209 1.0000 80 chr7:156741646-156741726 1.0000 80 chr2:798158-798238 1.0000 80 chr19:39988697-39988777 1.0000 80 chr22:37415792-37415872 1.0000 80 chr8:140771215-140771295 1.0000 80 chr12:53278835-53278915 1.0000 80 chr11:59521659-59521739 1.0000 80 chr19:35867095-35867175 1.0000 80 chr7:75368066-75368146 1.0000 80 chr12:128476112-12847619 1.0000 80 chr16:58059527-58059607 1.0000 80 chr1:76229901-76229981 1.0000 80 chr6:24659290-24659370 1.0000 80 chr16:88850650-88850730 1.0000 80 chr17:6478701-6478781 1.0000 80 chrX:55187716-55187796 1.0000 80 chr6:1554079-1554159 1.0000 80 chr19:2785901-2785981 1.0000 80 chr2:12858477-12858557 1.0000 80 chr5:70882362-70882442 1.0000 80 chr13:21585018-21585098 1.0000 80 chr1:93250595-93250675 1.0000 80 chr2:32583211-32583291 1.0000 80 chr22:25518143-25518223 1.0000 80 chr2:171571274-171571354 1.0000 80 chr4:48271553-48271633 1.0000 80 chr5:176981055-176981135 1.0000 80 chr21:36261657-36261737 1.0000 80 chr10:134781278-13478135 1.0000 80 chr20:25731126-25731206 1.0000 80 chr19:4577494-4577574 1.0000 80 chr11:117688468-11768854 1.0000 80 chr8:144660853-144660933 1.0000 80 chrX:1999917-1999997 1.0000 80 chr7:39454123-39454203 1.0000 80 chr1:55353084-55353164 1.0000 80 chr19:54693434-54693514 1.0000 80 chr5:139051259-139051339 1.0000 80 chr2:96823550-96823630 1.0000 80 chr10:29431558-29431638 1.0000 80 chr19:44278394-44278474 1.0000 80 chr17:73266607-73266687 1.0000 80 chr8:12679331-12679411 1.0000 80 chr1:85190192-85190272 1.0000 80 chrX:129091606-129091686 1.0000 80 chr6:123911229-123911309 1.0000 80 chr13:22177776-22177856 1.0000 80 chr9:131938179-131938259 1.0000 80 chr6:147370432-147370512 1.0000 80 chr8:142139648-142139728 1.0000 80 chr15:65544868-65544948 1.0000 80 chr7:140885523-140885603 1.0000 80 chr19:46080579-46080659 1.0000 80 chr7:137910866-137910946 1.0000 80 chr6:12200299-12200379 1.0000 80 chr10:3826970-3827050 1.0000 80 chr16:1327998-1328078 1.0000 80 chr12:117536600-11753668 1.0000 80 chr5:150537318-150537398 1.0000 80 chr22:21056768-21056848 1.0000 80 chr16:46588463-46588543 1.0000 80 chr15:41245825-41245905 1.0000 80 chr20:42137005-42137085 1.0000 80 chr19:38908621-38908701 1.0000 80 chr3:49727048-49727128 1.0000 80 chr22:36851179-36851259 1.0000 80 chr8:8751409-8751489 1.0000 80 chr16:46667248-46667328 1.0000 80 chr4:1748109-1748189 1.0000 80 chr16:85309295-85309375 1.0000 80 chr19:48794547-48794627 1.0000 80 chr13:47370762-47370842 1.0000 80 chr9:90449760-90449840 1.0000 80 chr6:155963922-155964002 1.0000 80 chr2:111880581-111880661 1.0000 80 chr6:106348579-106348659 1.0000 80 chr1:11740881-11740961 1.0000 80 chr9:136285587-136285667 1.0000 80 chr20:50163466-50163546 1.0000 80 chr13:27936508-27936588 1.0000 80 chr5:95298030-95298110 1.0000 80 chr14:101696610-10169669 1.0000 80 chr2:27806154-27806234 1.0000 80 chr22:30234259-30234339 1.0000 80 chr16:88590140-88590220 1.0000 80 chr16:47813855-47813935 1.0000 80 chr2:43134238-43134318 1.0000 80 chr19:50441138-50441218 1.0000 80 chr4:6332956-6333036 1.0000 80 chr21:44723906-44723986 1.0000 80 chr5:38798121-38798201 1.0000 80 chr9:102668730-102668810 1.0000 80 chr6:27799356-27799436 1.0000 80 chr11:98603841-98603921 1.0000 80 chr12:15841327-15841407 1.0000 80 chr1:10062964-10063044 1.0000 80 chr9:130159489-130159569 1.0000 80 chr6:33133713-33133793 1.0000 80 chr19:56915253-56915333 1.0000 80 chr22:39615446-39615526 1.0000 80 chr13:96336299-96336379 1.0000 80 chr10:99257589-99257669 1.0000 80 chr4:185570909-185570989 1.0000 80 chr17:38059851-38059931 1.0000 80 chrX:150067418-150067498 1.0000 80 chr6:126656548-126656628 1.0000 80 chr5:148064594-148064674 1.0000 80 chr16:838694-838774 1.0000 80 ******************************************************************************** ******************************************************************************** COMMAND LINE SUMMARY ******************************************************************************** This information can also be useful in the event you wish to report a problem with the MEME software. command: meme -oc ../result/final_prediction/K562/inference_raw/MEME/RankLinear0.6_40_HINFP/ -dna -nmotifs 5 -w 8 -maxsize 250000 -nostatus ../result/final_prediction/K562/fasta/RankLinear0.6_40/HINFP.fasta model: mod= zoops nmotifs= 5 evt= inf objective function: em= E-value of product of p-values starts= E-value of product of p-values strands: + width: minw= 8 maxw= 8 nsites: minsites= 2 maxsites= 250 wnsites= 0.8 theta: spmap= uni spfuzz= 0.5 em: prior= dirichlet b= 0.01 maxiter= 50 distance= 1e-05 trim: wg= 11 ws= 1 endgaps= yes data: n= 20000 N= 250 sample: seed= 0 hsfrac= 0 searchsize= 20000 norand= no csites= 1000 Letter frequencies in dataset: A 0.215 C 0.282 G 0.305 T 0.198 Background letter frequencies (from file dataset with add-one prior applied): A 0.215 C 0.282 G 0.305 T 0.198 Background model order: 0 ******************************************************************************** ******************************************************************************** MOTIF KGAGGACH MEME-1 width = 8 sites = 88 llr = 648 E-value = 1.8e-027 ******************************************************************************** -------------------------------------------------------------------------------- Motif KGAGGACH MEME-1 Description -------------------------------------------------------------------------------- Simplified A 1:912a13 pos.-specific C ::1:::94 probability G 4a:98::: matrix T 6::::::4 bits 2.3 2.1 * 1.9 * 1.6 ** * Relative 1.4 *** ** Entropy 1.2 ****** (10.6 bits) 0.9 ****** 0.7 ******* 0.5 ******** 0.2 ******** 0.0 -------- Multilevel TGAGGACT consensus G C sequence A -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif KGAGGACH MEME-1 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr22:39615446-39615526 55 1.45e-05 tggaccagat tgaggact agctaaaaca chr1:10062964-10063044 55 1.45e-05 cggaccaaac tgaggact aactaaaaca chr6:12200299-12200379 65 1.45e-05 cggaccagat tgaggact agcaaata chr22:25518143-25518223 33 1.45e-05 cggaccacat tgaggact agctaaaaca chr19:35867095-35867175 40 1.45e-05 tggaccaaat tgaggact agctaaaaca chr3:69745620-69745700 58 1.45e-05 tggaccaaat tgaggact agctaaaaca chr7:49997-50077 73 1.45e-05 cggaccagat tgaggact chr8:142034530-142034610 58 1.45e-05 GGAAGGCCAC TGAGGACT CTGGAGGGGA chr9:35574734-35574814 51 1.45e-05 cggaccaaat tgaggact agctaaaaca chrX:133282436-133282516 53 1.45e-05 cggaccagat tgaggact agctaaaaca chr18:33656451-33656531 31 1.45e-05 cggacctgat tgaggact ggagcaggac chr6:137092481-137092561 30 1.45e-05 cggaccagat tgaggact agctaaaaca chr1:205735872-205735952 11 3.52e-05 GATAGTATCC TGAGGACC GAAGAGAGAC chr20:61406313-61406393 23 3.52e-05 TTGGTCCCTG TGAGGACC CACATGAGGG chr18:711522-711602 44 3.52e-05 CGAGGGGCAG TGAGGACC CAGTGGGGAA chr12:15841327-15841407 28 5.09e-05 tggacctaga tgaggaca ggcatttttg chr10:29431558-29431638 25 5.09e-05 cgggcccagg tgaggaca ggcactcctg chr13:22614966-22615046 42 5.09e-05 tggacctagg tgaggaca ggcaattcag chr12:31934980-31935060 38 5.09e-05 cggacctagg tgaggaca ggcatttccg chr21:45905313-45905393 26 5.09e-05 cggacctggg tgaggaca ggcacttctg chr11:95998676-95998756 28 5.09e-05 cggacctagg tgaggaca ggcatttttg chr6:26071545-26071625 13 5.09e-05 gggaccacgg tgaggaca ggcatttttg chr17:42706268-42706348 39 5.09e-05 cggacctagg tgaggaca ggcatttttg chr22:19654833-19654913 28 5.09e-05 cggacctagg tgaggaca ggcatttttg chr22:20177996-20178076 37 5.09e-05 tggacctagg tgaggaca ggcatttcct chr11:106047619-10604769 58 5.09e-05 cggacctagg tgaggaca ggtatttcct chr17:72453431-72453511 45 5.09e-05 AGGACCCATT TGAGGACA GGCTGGACGT chr11:78316560-78316640 31 5.09e-05 cggacctagg tgaggaca ggcactcctg chr13:96336299-96336379 58 7.32e-05 gggacagttt ggaggact cagaggaaga chr5:95298030-95298110 57 7.32e-05 GGACGCAGCA GGAGGACT CGCTAGAGAG chr6:1554079-1554159 35 7.32e-05 GTAACCAGGT GGAGGACt gtgatgggaa chr16:86794817-86794897 38 7.32e-05 TTGAAGTCAC GGAGGACT CAGAGGAGGA chr20:50163466-50163546 19 1.05e-04 atgaaacgat ggaggacc cgaaagaaga chr16:1327998-1328078 17 1.05e-04 gaggagggag ggaggACC CAGGAGGAGA chr16:88850650-88850730 48 1.05e-04 GTAGGGCAAG GGAGGACC AGGGAGGAAC chr5:42757485-42757565 10 1.05e-04 CAGCAGACA GGAGGACC CAAAAGGAAA chr17:7589421-7589501 24 1.05e-04 AGGGCTGCAC GGAGGACC ACACGGACGC chr15:58357247-58357327 38 1.05e-04 TCCGGGCTGT GGAGGACC TGATTGGGAC chr2:106286084-106286164 31 1.05e-04 tgggggtgtt ggaggacc aaaagggaac chr16:89573979-89574059 2 1.05e-04 C GGAGGACC CCGCGCGCCT chr2:201520820-201520900 70 1.05e-04 ATCTGTTCTA GGAGGACC ATT chr12:56561977-56562057 35 1.05e-04 CACATCAGTG GGAGGACC CAACTGAAGA chr10:46762624-46762704 3 1.05e-04 CC GGAGGACC GGGGGAGTAC chr5:10539849-10539929 42 1.05e-04 CCAGCGCAGT GGAGGACC AGAGAGAAAA chr11:98603841-98603921 52 1.40e-04 tggaccggat tgagaact tgtcttcctg chr5:150537318-150537398 39 1.40e-04 GGGCGGACCG GGAGGACA GCCGTGGGCT chr19:39470683-39470763 54 1.40e-04 cggaccagat tgagaact tgtcttcctg chr14:97230499-97230579 35 1.40e-04 cggaccctat tgagaact gtgcatgcaa chr6:27799356-27799436 34 1.54e-04 CGGACCGAAC TGAGAACC TGAAAGAAGT chr7:44769174-44769254 50 1.54e-04 cggaccagat tgagaacc tctgttccca chr16:85762575-85762655 64 1.54e-04 cggaccccac tgagaacc aTGCAGCAG chr13:21585018-21585098 28 1.65e-04 tggacctgag tgagaaca tggacagaaa chr8:80673391-80673471 34 1.65e-04 AGGACCCAGT TGAGAACA CCTTTGGAAG chr12:128476112-12847619 68 1.75e-04 aggaccaaat tgaagact agcta chr19:40037379-40037459 30 1.75e-04 tggaccagac tgaagact aggtaaaaca chr17:6478701-6478781 5 2.66e-04 ACAG TGAAGACA GAGGAACGAT chr6:24659290-24659370 43 2.66e-04 ccaaccagtt tgaagaca ccccgacagg chr1:76229901-76229981 15 2.66e-04 actcctcccc agaggacc aaggtgaaag chr8:91251826-91251906 40 2.66e-04 ctgtggctgc agaggacc acatggaaag chr8:101446339-101446419 70 3.25e-04 TGGACCAGAG GGAGAACC AAG chr19:7939430-7939510 41 3.57e-04 CAGCTGCGCC TGAGGAAC CCAGATAGTC chr5:150428237-150428317 40 3.57e-04 AGAACCCAAG GGAGAACA GCCGAGTCTA chr2:145290968-145291048 39 3.57e-04 cacggacccg tgaggaac caggccacac chr4:1875218-1875298 20 4.12e-04 TGCTGAAGTG TGCGGACC CAAATGAAGC chr17:79375987-79376067 13 4.12e-04 TCCTCCCCCC TGCGGACC GAAGAGAACG chr19:1203120-1203200 48 4.12e-04 TGTGGGACTC TGAGGAAA AGCTCGCACC chr6:43061687-43061767 66 4.12e-04 tctacgcaaa ggaagact gggccag chr20:32777681-32777761 28 4.55e-04 TTCCCAGTTG GGAAGACC ATTCCTCAGC chr9:136285587-136285667 14 5.59e-04 cgtcttttgt agagaact tcctgcccag chr7:39454123-39454203 39 5.59e-04 CTCCGCGGGC GGCGGACT TGACAGGAAG chr11:59521659-59521739 35 5.59e-04 CGGACGCGAG AGAGAACT ACGGCCGAGA chr17:27276555-27276635 24 5.59e-04 GCAAAGAAGA GGCGGACT CGAGAGACAC chr16:1429929-1430009 25 5.59e-04 AGCTGCTCCG GGCGGACT CAGGTGAAAC chr8:29197828-29197908 14 5.59e-04 TACAGACTCA GGCGGACT GCTAGGAAGG chr15:43806610-43806690 9 5.59e-04 TCTGTTAG TGAGGACG CAAAGGGGAC chr7:137910866-137910946 21 5.94e-04 GTGTAGGCCC TGAAAACC TCCTGCCTGT chr9:127532796-127532876 7 5.94e-04 GTGGGA GGAGGAAC CCCTGTAGGG chr11:117688468-11768854 48 6.86e-04 CACGGCACCG GGCGGACC ATTCAGGAGC chr19:2785901-2785981 20 6.86e-04 cgggccccgt ggcggacc ctggggaggc chr2:219134646-219134726 51 6.86e-04 ACCTGGGTCC GGCGGACC GGGATCAAGT chr11:102256247-10225632 21 6.86e-04 caacatttgg ggaggaaa acaaaaatgc chr22:19284516-19284596 20 6.86e-04 agggtggtct tgagaaat acaacatttg chr21:44723906-44723986 69 7.54e-04 AAAAGCACTG AGAAGACT CCGC chr8:145100883-145100963 43 8.76e-04 CCCAGGCCCA GGAGGACG CAGATGGAGA chr8:144660853-144660933 25 9.14e-04 CCACCGACCC AGAAGACA ACCGCTGGCC chr19:44278394-44278474 65 9.50e-04 CAGTGGCGGA AGCGGACT TGATTGAG chr9:130159489-130159569 38 1.14e-03 CCGAGGACCC AGAGGAAA CCCAGCCGCT chr19:38908621-38908701 66 1.20e-03 CGCTGGGGCC TGGGGACT GGGGATT -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif KGAGGACH MEME-1 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr22:39615446-39615526 1.4e-05 54_[+1]_18 chr1:10062964-10063044 1.4e-05 54_[+1]_18 chr6:12200299-12200379 1.4e-05 64_[+1]_8 chr22:25518143-25518223 1.4e-05 32_[+1]_40 chr19:35867095-35867175 1.4e-05 39_[+1]_33 chr3:69745620-69745700 1.4e-05 57_[+1]_15 chr7:49997-50077 1.4e-05 72_[+1] chr8:142034530-142034610 1.4e-05 57_[+1]_15 chr9:35574734-35574814 1.4e-05 50_[+1]_22 chrX:133282436-133282516 1.4e-05 52_[+1]_20 chr18:33656451-33656531 1.4e-05 30_[+1]_42 chr6:137092481-137092561 1.4e-05 29_[+1]_43 chr1:205735872-205735952 3.5e-05 10_[+1]_62 chr20:61406313-61406393 3.5e-05 22_[+1]_50 chr18:711522-711602 3.5e-05 43_[+1]_29 chr12:15841327-15841407 5.1e-05 27_[+1]_45 chr10:29431558-29431638 5.1e-05 24_[+1]_48 chr13:22614966-22615046 5.1e-05 41_[+1]_31 chr12:31934980-31935060 5.1e-05 37_[+1]_35 chr21:45905313-45905393 5.1e-05 25_[+1]_47 chr11:95998676-95998756 5.1e-05 27_[+1]_45 chr6:26071545-26071625 5.1e-05 12_[+1]_60 chr17:42706268-42706348 5.1e-05 38_[+1]_34 chr22:19654833-19654913 5.1e-05 27_[+1]_45 chr22:20177996-20178076 5.1e-05 36_[+1]_36 chr11:106047619-10604769 5.1e-05 57_[+1]_15 chr17:72453431-72453511 5.1e-05 44_[+1]_28 chr11:78316560-78316640 5.1e-05 30_[+1]_42 chr13:96336299-96336379 7.3e-05 57_[+1]_15 chr5:95298030-95298110 7.3e-05 56_[+1]_16 chr6:1554079-1554159 7.3e-05 34_[+1]_38 chr16:86794817-86794897 7.3e-05 37_[+1]_35 chr20:50163466-50163546 0.00011 18_[+1]_54 chr16:1327998-1328078 0.00011 16_[+1]_56 chr16:88850650-88850730 0.00011 47_[+1]_25 chr5:42757485-42757565 0.00011 9_[+1]_63 chr17:7589421-7589501 0.00011 23_[+1]_49 chr15:58357247-58357327 0.00011 37_[+1]_35 chr2:106286084-106286164 0.00011 30_[+1]_42 chr16:89573979-89574059 0.00011 1_[+1]_71 chr2:201520820-201520900 0.00011 69_[+1]_3 chr12:56561977-56562057 0.00011 34_[+1]_38 chr10:46762624-46762704 0.00011 2_[+1]_70 chr5:10539849-10539929 0.00011 41_[+1]_31 chr11:98603841-98603921 0.00014 51_[+1]_21 chr5:150537318-150537398 0.00014 38_[+1]_34 chr19:39470683-39470763 0.00014 53_[+1]_19 chr14:97230499-97230579 0.00014 34_[+1]_38 chr6:27799356-27799436 0.00015 33_[+1]_39 chr7:44769174-44769254 0.00015 49_[+1]_23 chr16:85762575-85762655 0.00015 63_[+1]_9 chr13:21585018-21585098 0.00017 27_[+1]_45 chr8:80673391-80673471 0.00017 33_[+1]_39 chr12:128476112-12847619 0.00018 67_[+1]_5 chr19:40037379-40037459 0.00018 29_[+1]_43 chr17:6478701-6478781 0.00027 4_[+1]_68 chr6:24659290-24659370 0.00027 42_[+1]_30 chr1:76229901-76229981 0.00027 14_[+1]_58 chr8:91251826-91251906 0.00027 39_[+1]_33 chr8:101446339-101446419 0.00032 69_[+1]_3 chr19:7939430-7939510 0.00036 40_[+1]_32 chr5:150428237-150428317 0.00036 39_[+1]_33 chr2:145290968-145291048 0.00036 38_[+1]_34 chr4:1875218-1875298 0.00041 19_[+1]_53 chr17:79375987-79376067 0.00041 12_[+1]_60 chr19:1203120-1203200 0.00041 47_[+1]_25 chr6:43061687-43061767 0.00041 65_[+1]_7 chr20:32777681-32777761 0.00046 27_[+1]_45 chr9:136285587-136285667 0.00056 13_[+1]_59 chr7:39454123-39454203 0.00056 38_[+1]_34 chr11:59521659-59521739 0.00056 34_[+1]_38 chr17:27276555-27276635 0.00056 23_[+1]_49 chr16:1429929-1430009 0.00056 24_[+1]_48 chr8:29197828-29197908 0.00056 13_[+1]_59 chr15:43806610-43806690 0.00056 8_[+1]_64 chr7:137910866-137910946 0.00059 20_[+1]_52 chr9:127532796-127532876 0.00059 6_[+1]_66 chr11:117688468-11768854 0.00069 47_[+1]_25 chr19:2785901-2785981 0.00069 19_[+1]_53 chr2:219134646-219134726 0.00069 50_[+1]_22 chr11:102256247-10225632 0.00069 20_[+1]_52 chr22:19284516-19284596 0.00069 19_[+1]_53 chr21:44723906-44723986 0.00075 68_[+1]_4 chr8:145100883-145100963 0.00088 42_[+1]_30 chr8:144660853-144660933 0.00091 24_[+1]_48 chr19:44278394-44278474 0.00095 64_[+1]_8 chr9:130159489-130159569 0.0011 37_[+1]_35 chr19:38908621-38908701 0.0012 65_[+1]_7 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif KGAGGACH MEME-1 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF KGAGGACH width=8 seqs=88 chr22:39615446-39615526 ( 55) TGAGGACT 1 chr1:10062964-10063044 ( 55) TGAGGACT 1 chr6:12200299-12200379 ( 65) TGAGGACT 1 chr22:25518143-25518223 ( 33) TGAGGACT 1 chr19:35867095-35867175 ( 40) TGAGGACT 1 chr3:69745620-69745700 ( 58) TGAGGACT 1 chr7:49997-50077 ( 73) TGAGGACT 1 chr8:142034530-142034610 ( 58) TGAGGACT 1 chr9:35574734-35574814 ( 51) TGAGGACT 1 chrX:133282436-133282516 ( 53) TGAGGACT 1 chr18:33656451-33656531 ( 31) TGAGGACT 1 chr6:137092481-137092561 ( 30) TGAGGACT 1 chr1:205735872-205735952 ( 11) TGAGGACC 1 chr20:61406313-61406393 ( 23) TGAGGACC 1 chr18:711522-711602 ( 44) TGAGGACC 1 chr12:15841327-15841407 ( 28) TGAGGACA 1 chr10:29431558-29431638 ( 25) TGAGGACA 1 chr13:22614966-22615046 ( 42) TGAGGACA 1 chr12:31934980-31935060 ( 38) TGAGGACA 1 chr21:45905313-45905393 ( 26) TGAGGACA 1 chr11:95998676-95998756 ( 28) TGAGGACA 1 chr6:26071545-26071625 ( 13) TGAGGACA 1 chr17:42706268-42706348 ( 39) TGAGGACA 1 chr22:19654833-19654913 ( 28) TGAGGACA 1 chr22:20177996-20178076 ( 37) TGAGGACA 1 chr11:106047619-10604769 ( 58) TGAGGACA 1 chr17:72453431-72453511 ( 45) TGAGGACA 1 chr11:78316560-78316640 ( 31) TGAGGACA 1 chr13:96336299-96336379 ( 58) GGAGGACT 1 chr5:95298030-95298110 ( 57) GGAGGACT 1 chr6:1554079-1554159 ( 35) GGAGGACT 1 chr16:86794817-86794897 ( 38) GGAGGACT 1 chr20:50163466-50163546 ( 19) GGAGGACC 1 chr16:1327998-1328078 ( 17) GGAGGACC 1 chr16:88850650-88850730 ( 48) GGAGGACC 1 chr5:42757485-42757565 ( 10) GGAGGACC 1 chr17:7589421-7589501 ( 24) GGAGGACC 1 chr15:58357247-58357327 ( 38) GGAGGACC 1 chr2:106286084-106286164 ( 31) GGAGGACC 1 chr16:89573979-89574059 ( 2) GGAGGACC 1 chr2:201520820-201520900 ( 70) GGAGGACC 1 chr12:56561977-56562057 ( 35) GGAGGACC 1 chr10:46762624-46762704 ( 3) GGAGGACC 1 chr5:10539849-10539929 ( 42) GGAGGACC 1 chr11:98603841-98603921 ( 52) TGAGAACT 1 chr5:150537318-150537398 ( 39) GGAGGACA 1 chr19:39470683-39470763 ( 54) TGAGAACT 1 chr14:97230499-97230579 ( 35) TGAGAACT 1 chr6:27799356-27799436 ( 34) TGAGAACC 1 chr7:44769174-44769254 ( 50) TGAGAACC 1 chr16:85762575-85762655 ( 64) TGAGAACC 1 chr13:21585018-21585098 ( 28) TGAGAACA 1 chr8:80673391-80673471 ( 34) TGAGAACA 1 chr12:128476112-12847619 ( 68) TGAAGACT 1 chr19:40037379-40037459 ( 30) TGAAGACT 1 chr17:6478701-6478781 ( 5) TGAAGACA 1 chr6:24659290-24659370 ( 43) TGAAGACA 1 chr1:76229901-76229981 ( 15) AGAGGACC 1 chr8:91251826-91251906 ( 40) AGAGGACC 1 chr8:101446339-101446419 ( 70) GGAGAACC 1 chr19:7939430-7939510 ( 41) TGAGGAAC 1 chr5:150428237-150428317 ( 40) GGAGAACA 1 chr2:145290968-145291048 ( 39) TGAGGAAC 1 chr4:1875218-1875298 ( 20) TGCGGACC 1 chr17:79375987-79376067 ( 13) TGCGGACC 1 chr19:1203120-1203200 ( 48) TGAGGAAA 1 chr6:43061687-43061767 ( 66) GGAAGACT 1 chr20:32777681-32777761 ( 28) GGAAGACC 1 chr9:136285587-136285667 ( 14) AGAGAACT 1 chr7:39454123-39454203 ( 39) GGCGGACT 1 chr11:59521659-59521739 ( 35) AGAGAACT 1 chr17:27276555-27276635 ( 24) GGCGGACT 1 chr16:1429929-1430009 ( 25) GGCGGACT 1 chr8:29197828-29197908 ( 14) GGCGGACT 1 chr15:43806610-43806690 ( 9) TGAGGACG 1 chr7:137910866-137910946 ( 21) TGAAAACC 1 chr9:127532796-127532876 ( 7) GGAGGAAC 1 chr11:117688468-11768854 ( 48) GGCGGACC 1 chr19:2785901-2785981 ( 20) GGCGGACC 1 chr2:219134646-219134726 ( 51) GGCGGACC 1 chr11:102256247-10225632 ( 21) GGAGGAAA 1 chr22:19284516-19284596 ( 20) TGAGAAAT 1 chr21:44723906-44723986 ( 69) AGAAGACT 1 chr8:145100883-145100963 ( 43) GGAGGACG 1 chr8:144660853-144660933 ( 25) AGAAGACA 1 chr19:44278394-44278474 ( 65) AGCGGACT 1 chr9:130159489-130159569 ( 38) AGAGGAAA 1 chr19:38908621-38908701 ( 66) TGGGGACT 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif KGAGGACH MEME-1 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 8.04582 E= 1.8e-027 -124 -1310 21 149 -1310 -1310 171 -1310 203 -131 -474 -1310 -107 -1310 156 -1310 -43 -1310 146 -1310 222 -1310 -1310 -1310 -143 170 -1310 -1310 28 32 -375 88 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif KGAGGACH MEME-1 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 88 E= 1.8e-027 0.090909 0.000000 0.352273 0.556818 0.000000 0.000000 1.000000 0.000000 0.875000 0.113636 0.011364 0.000000 0.102273 0.000000 0.897727 0.000000 0.159091 0.000000 0.840909 0.000000 1.000000 0.000000 0.000000 0.000000 0.079545 0.920455 0.000000 0.000000 0.261364 0.352273 0.022727 0.363636 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif KGAGGACH MEME-1 regular expression -------------------------------------------------------------------------------- [TG]GAGGAC[TCA] -------------------------------------------------------------------------------- Time 4.99 secs. ******************************************************************************** ******************************************************************************** MOTIF DGGTCCGY MEME-2 width = 8 sites = 82 llr = 608 E-value = 2.8e-024 ******************************************************************************** -------------------------------------------------------------------------------- Motif DGGTCCGY MEME-2 Description -------------------------------------------------------------------------------- Simplified A 3::::::: pos.-specific C 1:::aa15 probability G 2aa:::72 matrix T 3::a::23 bits 2.3 * 2.1 * 1.9 *** 1.6 ***** Relative 1.4 ***** Entropy 1.2 ***** (10.7 bits) 0.9 ***** 0.7 ****** 0.5 ******* 0.2 ******** 0.0 -------- Multilevel AGGTCCGC consensus T T sequence G G -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif DGGTCCGY MEME-2 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr4:6332956-6333036 45 5.20e-05 tgtcaatcta aggtccgc tgcttgctgg chr6:155963922-155964002 73 5.20e-05 ggcaactcac aggtccgc chr12:117536600-11753668 13 5.20e-05 GTTCCCACCC AGGTCCGC CGACTTCAAA chr8:142139648-142139728 49 5.20e-05 GGTTTCCTCC TGGTCCGC CTGTCTGTGA chr19:4577494-4577574 54 5.20e-05 GCTCCCTCCT AGGTCCGC CCTTGGAAGG chr2:12858477-12858557 47 5.20e-05 GTCGTCTATA AGGTCCGC GGAGCCCAGC chr8:140771215-140771295 50 5.20e-05 GTTCTCTTTC TGGTCCGC CTCAGCATGC chr22:37415792-37415872 11 5.20e-05 CTCCTCCCTT TGGTCCGC TGCAGGTTGG chr20:47936099-47936179 63 5.20e-05 AGTCCATCTG TGGTCCGC GTGCTGGGCG chr12:51611008-51611088 52 5.20e-05 GCGTCCCCTG TGGTCCGC ACCCCACAAG chr8:101804306-101804386 15 5.20e-05 GGCTCCGATG TGGTCCGC TGAAAGTGGT chr7:116853135-116853215 43 5.20e-05 GCTCCCTCTC AGGTCCGC TGGCCATGCA chr5:38798121-38798201 54 8.86e-05 gtccccacct aggtccgt gggggtagag chr14:101696610-10169669 71 8.86e-05 gtcctcatct aggtccgt gg chr9:90449760-90449840 42 8.86e-05 gtcctcacct aggtccgt gggcacaggc chr8:12679331-12679411 50 8.86e-05 gtcctcacct aggtccgt gggggtggag chr20:25731126-25731206 33 8.86e-05 gtcctcacct aggtccgt gggggtggag chr10:134781278-13478135 54 8.86e-05 gtcctcacct aggtccgt gggggtggag chr2:798158-798238 70 8.86e-05 gctctcactt aggtccgt gga chr7:156741646-156741726 26 8.86e-05 GGCGTCTCCC TGGTCCGT ATCCAGAGCC chr18:48650652-48650732 46 8.86e-05 gtcctcacct aggtccgt gggggtggag chr12:47475106-47475186 41 8.86e-05 GTTTCCTACA TGGTCCGT GAGTCATTGC chr11:102256247-10225632 51 8.86e-05 gtcctcacct aggtccgt ggggttggaa chr16:25377514-25377594 56 8.86e-05 GTCCCCACTT AGGTCCGT AGAGGGAGGT chr22:19620468-19620548 24 8.86e-05 gtcctcactt aggtccgt gggggtggag chr22:19284516-19284596 62 8.86e-05 gtcctcacct aggtccgt ggggggtgga chr5:145921992-145922072 53 8.86e-05 GGCTGCAAAC AGGTCCGT GGGGCACAAA chr1:94194417-94194497 62 8.86e-05 gtcctcactt aggtccgt gggggtggag chr19:4754410-4754490 49 8.86e-05 gtcctcaatc aggtccgt tgtctgggcc chr6:33133713-33133793 34 1.27e-04 TCTCTCCCTT GGGTCCGC CTGGGCCCTG chr13:27936508-27936588 53 1.27e-04 GAGCTCCCCG GGGTCCGC CCTGACCCGT chr1:55353084-55353164 11 1.27e-04 GGTGCCGGTG GGGTCCGC TGCGAATACT chrX:55187716-55187796 18 1.27e-04 TGTTTCCTCT GGGTCCGC CGCAGGCTCC chr16:58059527-58059607 72 1.27e-04 GTCCCCGCCC GGGTCCGC G chr8:23365264-23365344 26 1.27e-04 GTCTCCTCCA GGGTCCGC CATTCATTCT chrX:129091606-129091686 11 1.54e-04 GACTTCCCTG GGGTCCGT TTCGGGGGCT chr19:56915253-56915333 58 2.44e-04 GGCTCCACAC TGGTCCTC CAGCTCCCTT chr21:44723906-44723986 12 2.44e-04 gtcctcaatc tggtccgg agtcaagtcc chr7:137910866-137910946 49 2.44e-04 GGCCTCTGTT TGGTCCTC CTGGACTTCC chr6:147370432-147370512 48 2.44e-04 gtctcctaac tggtcctc ctgcttcact chr17:45820293-45820373 35 2.44e-04 CTTCCCTGCC TGGTCCTC CCCCTGTGTC chr19:17420576-17420656 2 2.44e-04 C AGGTCCGG CCCGCCCCTC chr9:136114363-136114443 18 2.44e-04 GTCTTCCCAG TGGTCCTC TCCTGAGCAC chr3:52567027-52567107 61 2.44e-04 GTGTCCCCTT TGGTCCGG CCGTCCCTAG chr2:209100743-209100823 50 2.44e-04 GTTCCCTCTT TGGTCCTC TTTCCTTTCA chr1:31121414-31121494 39 2.44e-04 gtcctcaatt tggtccgg tgtccaagcc chr4:138827264-138827344 39 2.44e-04 gagccctgtg tggtccgg tgttaagaag chr11:111956692-11195677 49 2.44e-04 GTTCTCTCTA AGGTCCTC AAGGATAGCT chr16:3181995-3182075 27 2.44e-04 GTCCTCacct tggtccgg ctcctgccct chr19:35453901-35453981 41 2.44e-04 gtcctcactc tggtccgg ccagccgcag chr22:21056768-21056848 30 2.68e-04 AGCCTGCGGC TGGTCCTT CCTGGCGACT chr14:38065267-38065347 5 3.03e-04 GCCT CGGTCCGC TCCTCTCCCC chrX:24483055-24483135 56 3.03e-04 GGCCTCTTCC CGGTCCGC GGGCACCTCG chr22:37374198-37374278 45 3.03e-04 TCCTTCCTTC CGGTCCGC TGCTGAGGCT chr7:140885523-140885603 32 3.28e-04 gtcctcacct cggtccgt gggggtggag chr5:42909192-42909272 54 3.28e-04 ggttcctaac cggtccgt ggtggggggg chr5:148064594-148064674 45 4.43e-04 GCTTTCAACA GGGTCCTC TGCTGCTCTT chr16:46667248-46667328 36 4.43e-04 gagacaccac aggtcccc actccagtcc chr15:65544868-65544948 66 4.43e-04 GTTTTCACTG GGGTCCTC CTTTGGC chr2:32583211-32583291 11 4.43e-04 CGACTAGACC TGGTCCCC TTGCTCGGGG chr1:93250595-93250675 41 4.43e-04 GGTTCCTCCG GGGTCCGG CCCGGCCGCG chr12:53278835-53278915 32 4.43e-04 GGTCCCACTC GGGTCCTC TCCTCCAAGC chr19:10535017-10535097 65 4.43e-04 GTCTCCACTT GGGTCCTC GCCTCCCC chr5:55386103-55386183 44 4.43e-04 gtcttctact gggtcctc tgcatctgac chr3:183872880-183872960 60 4.43e-04 GATCCCACTT GGGTCCGG AGTCAGGGCC chr19:1203120-1203200 24 4.43e-04 TGTCTCTGTT GGGTCCGG GTGCTCTGTG chr17:43129498-43129578 27 4.43e-04 CACGGCACAG AGGTCCCC CGCAACCCCC chr19:33166405-33166485 72 4.43e-04 GTCGCCGAca gggtccgg g chr11:117923684-11792376 59 4.43e-04 gctcacagcc gggtccgg tggctcacac chr17:72453431-72453511 9 4.43e-04 TAAGGCTG TGGTCCCC CAGCTTCCCC chr13:22614966-22615046 5 4.94e-04 ggcg tggtccct agctagggct chr12:31934980-31935060 1 4.94e-04 . tggtccct gcctagggct chr20:61406313-61406393 14 4.94e-04 GTCTTCCACT TGGTCCCT GTGAGGACCC chr2:145290968-145291048 10 4.94e-04 ctaaaacaa aggtccct aacccccagg chrX:150067418-150067498 13 5.92e-04 TGTCCCACCT CGGTCCTC GAGACCGAAG chr3:49727048-49727128 46 5.92e-04 ATTCCCTTCG CGGTCCGG GCTAGTCCAG chr11:117680117-11768019 24 5.92e-04 TGTGTCTCTG CGGTCCTC CGCGGAAGGA chr19:7939430-7939510 7 5.92e-04 TCTCTG CGGTCCGG GGGAAGCCTG chr2:61293674-61293754 36 5.92e-04 GGCTTCTTCC CGGTCCGG GATGACTCGG chr20:32777681-32777761 47 5.92e-04 TTCCTCAGCT CGGTCCGG TGGACTGCTG chr7:75368066-75368146 36 6.44e-04 GGATGCCCCG GGGTCCCC CGTCCTCACC chr16:85762575-85762655 48 7.48e-04 cctatacaga aggtcccg gaccccactg -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif DGGTCCGY MEME-2 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr4:6332956-6333036 5.2e-05 44_[+2]_28 chr6:155963922-155964002 5.2e-05 72_[+2] chr12:117536600-11753668 5.2e-05 12_[+2]_60 chr8:142139648-142139728 5.2e-05 48_[+2]_24 chr19:4577494-4577574 5.2e-05 53_[+2]_19 chr2:12858477-12858557 5.2e-05 46_[+2]_26 chr8:140771215-140771295 5.2e-05 49_[+2]_23 chr22:37415792-37415872 5.2e-05 10_[+2]_62 chr20:47936099-47936179 5.2e-05 62_[+2]_10 chr12:51611008-51611088 5.2e-05 51_[+2]_21 chr8:101804306-101804386 5.2e-05 14_[+2]_58 chr7:116853135-116853215 5.2e-05 42_[+2]_30 chr5:38798121-38798201 8.9e-05 53_[+2]_19 chr14:101696610-10169669 8.9e-05 70_[+2]_2 chr9:90449760-90449840 8.9e-05 41_[+2]_31 chr8:12679331-12679411 8.9e-05 49_[+2]_23 chr20:25731126-25731206 8.9e-05 32_[+2]_40 chr10:134781278-13478135 8.9e-05 53_[+2]_19 chr2:798158-798238 8.9e-05 69_[+2]_3 chr7:156741646-156741726 8.9e-05 25_[+2]_47 chr18:48650652-48650732 8.9e-05 45_[+2]_27 chr12:47475106-47475186 8.9e-05 40_[+2]_32 chr11:102256247-10225632 8.9e-05 50_[+2]_22 chr16:25377514-25377594 8.9e-05 55_[+2]_17 chr22:19620468-19620548 8.9e-05 23_[+2]_49 chr22:19284516-19284596 8.9e-05 61_[+2]_11 chr5:145921992-145922072 8.9e-05 52_[+2]_20 chr1:94194417-94194497 8.9e-05 61_[+2]_11 chr19:4754410-4754490 8.9e-05 48_[+2]_24 chr6:33133713-33133793 0.00013 33_[+2]_39 chr13:27936508-27936588 0.00013 52_[+2]_20 chr1:55353084-55353164 0.00013 10_[+2]_62 chrX:55187716-55187796 0.00013 17_[+2]_55 chr16:58059527-58059607 0.00013 71_[+2]_1 chr8:23365264-23365344 0.00013 25_[+2]_47 chrX:129091606-129091686 0.00015 10_[+2]_62 chr19:56915253-56915333 0.00024 57_[+2]_15 chr21:44723906-44723986 0.00024 11_[+2]_61 chr7:137910866-137910946 0.00024 48_[+2]_24 chr6:147370432-147370512 0.00024 47_[+2]_25 chr17:45820293-45820373 0.00024 34_[+2]_38 chr19:17420576-17420656 0.00024 1_[+2]_71 chr9:136114363-136114443 0.00024 17_[+2]_55 chr3:52567027-52567107 0.00024 60_[+2]_12 chr2:209100743-209100823 0.00024 49_[+2]_23 chr1:31121414-31121494 0.00024 38_[+2]_34 chr4:138827264-138827344 0.00024 38_[+2]_34 chr11:111956692-11195677 0.00024 48_[+2]_24 chr16:3181995-3182075 0.00024 26_[+2]_46 chr19:35453901-35453981 0.00024 40_[+2]_32 chr22:21056768-21056848 0.00027 29_[+2]_43 chr14:38065267-38065347 0.0003 4_[+2]_68 chrX:24483055-24483135 0.0003 55_[+2]_17 chr22:37374198-37374278 0.0003 44_[+2]_28 chr7:140885523-140885603 0.00033 31_[+2]_41 chr5:42909192-42909272 0.00033 53_[+2]_19 chr5:148064594-148064674 0.00044 44_[+2]_28 chr16:46667248-46667328 0.00044 35_[+2]_37 chr15:65544868-65544948 0.00044 65_[+2]_7 chr2:32583211-32583291 0.00044 10_[+2]_62 chr1:93250595-93250675 0.00044 40_[+2]_32 chr12:53278835-53278915 0.00044 31_[+2]_41 chr19:10535017-10535097 0.00044 64_[+2]_8 chr5:55386103-55386183 0.00044 43_[+2]_29 chr3:183872880-183872960 0.00044 59_[+2]_13 chr19:1203120-1203200 0.00044 23_[+2]_49 chr17:43129498-43129578 0.00044 26_[+2]_46 chr19:33166405-33166485 0.00044 71_[+2]_1 chr11:117923684-11792376 0.00044 58_[+2]_14 chr17:72453431-72453511 0.00044 8_[+2]_64 chr13:22614966-22615046 0.00049 4_[+2]_68 chr12:31934980-31935060 0.00049 [+2]_72 chr20:61406313-61406393 0.00049 13_[+2]_59 chr2:145290968-145291048 0.00049 9_[+2]_63 chrX:150067418-150067498 0.00059 12_[+2]_60 chr3:49727048-49727128 0.00059 45_[+2]_27 chr11:117680117-11768019 0.00059 23_[+2]_49 chr19:7939430-7939510 0.00059 6_[+2]_66 chr2:61293674-61293754 0.00059 35_[+2]_37 chr20:32777681-32777761 0.00059 46_[+2]_26 chr7:75368066-75368146 0.00064 35_[+2]_37 chr16:85762575-85762655 0.00075 47_[+2]_25 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif DGGTCCGY MEME-2 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF DGGTCCGY width=8 seqs=82 chr4:6332956-6333036 ( 45) AGGTCCGC 1 chr6:155963922-155964002 ( 73) AGGTCCGC 1 chr12:117536600-11753668 ( 13) AGGTCCGC 1 chr8:142139648-142139728 ( 49) TGGTCCGC 1 chr19:4577494-4577574 ( 54) AGGTCCGC 1 chr2:12858477-12858557 ( 47) AGGTCCGC 1 chr8:140771215-140771295 ( 50) TGGTCCGC 1 chr22:37415792-37415872 ( 11) TGGTCCGC 1 chr20:47936099-47936179 ( 63) TGGTCCGC 1 chr12:51611008-51611088 ( 52) TGGTCCGC 1 chr8:101804306-101804386 ( 15) TGGTCCGC 1 chr7:116853135-116853215 ( 43) AGGTCCGC 1 chr5:38798121-38798201 ( 54) AGGTCCGT 1 chr14:101696610-10169669 ( 71) AGGTCCGT 1 chr9:90449760-90449840 ( 42) AGGTCCGT 1 chr8:12679331-12679411 ( 50) AGGTCCGT 1 chr20:25731126-25731206 ( 33) AGGTCCGT 1 chr10:134781278-13478135 ( 54) AGGTCCGT 1 chr2:798158-798238 ( 70) AGGTCCGT 1 chr7:156741646-156741726 ( 26) TGGTCCGT 1 chr18:48650652-48650732 ( 46) AGGTCCGT 1 chr12:47475106-47475186 ( 41) TGGTCCGT 1 chr11:102256247-10225632 ( 51) AGGTCCGT 1 chr16:25377514-25377594 ( 56) AGGTCCGT 1 chr22:19620468-19620548 ( 24) AGGTCCGT 1 chr22:19284516-19284596 ( 62) AGGTCCGT 1 chr5:145921992-145922072 ( 53) AGGTCCGT 1 chr1:94194417-94194497 ( 62) AGGTCCGT 1 chr19:4754410-4754490 ( 49) AGGTCCGT 1 chr6:33133713-33133793 ( 34) GGGTCCGC 1 chr13:27936508-27936588 ( 53) GGGTCCGC 1 chr1:55353084-55353164 ( 11) GGGTCCGC 1 chrX:55187716-55187796 ( 18) GGGTCCGC 1 chr16:58059527-58059607 ( 72) GGGTCCGC 1 chr8:23365264-23365344 ( 26) GGGTCCGC 1 chrX:129091606-129091686 ( 11) GGGTCCGT 1 chr19:56915253-56915333 ( 58) TGGTCCTC 1 chr21:44723906-44723986 ( 12) TGGTCCGG 1 chr7:137910866-137910946 ( 49) TGGTCCTC 1 chr6:147370432-147370512 ( 48) TGGTCCTC 1 chr17:45820293-45820373 ( 35) TGGTCCTC 1 chr19:17420576-17420656 ( 2) AGGTCCGG 1 chr9:136114363-136114443 ( 18) TGGTCCTC 1 chr3:52567027-52567107 ( 61) TGGTCCGG 1 chr2:209100743-209100823 ( 50) TGGTCCTC 1 chr1:31121414-31121494 ( 39) TGGTCCGG 1 chr4:138827264-138827344 ( 39) TGGTCCGG 1 chr11:111956692-11195677 ( 49) AGGTCCTC 1 chr16:3181995-3182075 ( 27) TGGTCCGG 1 chr19:35453901-35453981 ( 41) TGGTCCGG 1 chr22:21056768-21056848 ( 30) TGGTCCTT 1 chr14:38065267-38065347 ( 5) CGGTCCGC 1 chrX:24483055-24483135 ( 56) CGGTCCGC 1 chr22:37374198-37374278 ( 45) CGGTCCGC 1 chr7:140885523-140885603 ( 32) CGGTCCGT 1 chr5:42909192-42909272 ( 54) CGGTCCGT 1 chr5:148064594-148064674 ( 45) GGGTCCTC 1 chr16:46667248-46667328 ( 36) AGGTCCCC 1 chr15:65544868-65544948 ( 66) GGGTCCTC 1 chr2:32583211-32583291 ( 11) TGGTCCCC 1 chr1:93250595-93250675 ( 41) GGGTCCGG 1 chr12:53278835-53278915 ( 32) GGGTCCTC 1 chr19:10535017-10535097 ( 65) GGGTCCTC 1 chr5:55386103-55386183 ( 44) GGGTCCTC 1 chr3:183872880-183872960 ( 60) GGGTCCGG 1 chr19:1203120-1203200 ( 24) GGGTCCGG 1 chr17:43129498-43129578 ( 27) AGGTCCCC 1 chr19:33166405-33166485 ( 72) GGGTCCGG 1 chr11:117923684-11792376 ( 59) GGGTCCGG 1 chr17:72453431-72453511 ( 9) TGGTCCCC 1 chr13:22614966-22615046 ( 5) TGGTCCCT 1 chr12:31934980-31935060 ( 1) TGGTCCCT 1 chr20:61406313-61406393 ( 14) TGGTCCCT 1 chr2:145290968-145291048 ( 10) AGGTCCCT 1 chrX:150067418-150067498 ( 13) CGGTCCTC 1 chr3:49727048-49727128 ( 46) CGGTCCGG 1 chr11:117680117-11768019 ( 24) CGGTCCTC 1 chr19:7939430-7939510 ( 7) CGGTCCGG 1 chr2:61293674-61293754 ( 36) CGGTCCGG 1 chr20:32777681-32777761 ( 47) CGGTCCGG 1 chr7:75368066-75368146 ( 36) GGGTCCCC 1 chr16:85762575-85762655 ( 48) AGGTCCCG 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif DGGTCCGY MEME-2 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 9.2854 E= 2.8e-024 62 -107 -48 68 -1300 -1300 171 -1300 -1300 -1300 171 -1300 -1300 -1300 -1300 234 -1300 182 -1300 -1300 -1300 182 -1300 -1300 -1300 -121 119 -11 -1300 79 -56 62 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif DGGTCCGY MEME-2 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 82 E= 2.8e-024 0.329268 0.134146 0.219512 0.317073 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.121951 0.695122 0.182927 0.000000 0.487805 0.207317 0.304878 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif DGGTCCGY MEME-2 regular expression -------------------------------------------------------------------------------- [ATG]GGTCCG[CTG] -------------------------------------------------------------------------------- Time 8.63 secs. ******************************************************************************** ******************************************************************************** MOTIF WGTYCYCW MEME-3 width = 8 sites = 99 llr = 688 E-value = 1.0e-020 ******************************************************************************** -------------------------------------------------------------------------------- Motif WGTYCYCW MEME-3 Description -------------------------------------------------------------------------------- Simplified A 5::::::6 pos.-specific C :12485a: probability G :7:::::: matrix T 538625:4 bits 2.3 2.1 1.9 * 1.6 * * Relative 1.4 * ** Entropy 1.2 * *** ** (10.0 bits) 0.9 * ****** 0.7 ******** 0.5 ******** 0.2 ******** 0.0 -------- Multilevel TGTTCCCA consensus AT CTT T sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif WGTYCYCW MEME-3 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr8:128990129-128990209 20 8.01e-06 GTTGCAGGCA TGTTCTCA CCCACGTCCG chr12:117536600-11753668 2 1.94e-05 C TGTTCCCA CCCAGGTCCG chr7:44769174-44769254 60 1.94e-05 tgagaacctc tgttccca tttggtgcac chr21:21226155-21226235 32 2.81e-05 atccatcata agttctca ctccggtctg chr2:219134646-219134726 34 2.81e-05 GAGGAGCGGC AGTTCTCA CCTGGGTCCG chr1:31545316-31545396 54 2.81e-05 acaggaagaa agttctca atacagtcgg chr12:83729602-83729682 40 2.81e-05 gctggataga agttctca ctttgggccg chr1:16843346-16843426 50 4.05e-05 tcacatgagc agttccca atagggtccg chr19:35453901-35453981 4 4.05e-05 tca agttccca atcacttcct chr14:101696610-10169669 60 6.45e-05 aggaaatgcc tgtcctca tctaggtccg chr9:90449760-90449840 31 6.45e-05 cagaaatgcc tgtcctca cctaggtccg chr8:12679331-12679411 39 6.45e-05 caggagtgcc tgtcctca cctaggtccg chr20:25731126-25731206 22 6.45e-05 caaaaatgcc tgtcctca cctaggtccg chr10:134781278-13478135 43 6.45e-05 aggaaattcc tgtcctca cctaggtccg chr8:140771215-140771295 39 6.45e-05 GAGGTGCCTC TGTTCTCT TTCTGGTCCG chr18:48650652-48650732 35 6.45e-05 gaaaaatgcc tgtcctca cctaggtccg chr11:102256247-10225632 40 6.45e-05 caaaaatgcc tgtcctca cctaggtccg chr22:19620468-19620548 13 6.45e-05 aggaaatgcc tgtcctca cttaggtccg chr22:19284516-19284596 51 6.45e-05 agaaaatgcc tgtcctca cctaggtccg chr16:3181995-3182075 16 6.45e-05 TCAGTTCCAC TGTCCTCa ccttggtccg chr1:94194417-94194497 51 6.45e-05 aaaaaatgcc tgtcctca cttaggtccg chr5:38798121-38798201 43 9.87e-05 caggagtgcc tgtcccca cctaggtccg chr16:88590140-88590220 55 9.87e-05 GTCTCCTACC TGTTCCCT CCCGGGTCGG chr1:85190192-85190272 31 9.87e-05 GCCCCCTGGC TGTTCCCT TTTGCAACAG chr17:17941976-17942056 34 9.87e-05 CGtgactcgc tgttccct ctcgggtcgt chr21:44723906-44723986 1 1.25e-04 . agtcctca atctggtccg chr22:21056768-21056848 6 1.25e-04 TTCCC AGTCCTCA ATCATGAGCC chr7:140885523-140885603 21 1.25e-04 caaaaatgcc agtcctca cctcggtccg chr12:117111634-11711171 1 1.25e-04 . agtcctca atgtggtcca chr1:31121414-31121494 28 1.25e-04 tgtcttagat agtcctca atttggtccg chr11:111956692-11195677 38 1.25e-04 CTAAGAAATC AGTTCTCT CTAAGGTCCT chr8:11654674-11654754 14 1.25e-04 tgttttagct agtcctca atttggtcgg chr19:4754410-4754490 38 1.25e-04 tgtattagct agtcctca atcaggtccg chr12:15841327-15841407 66 1.62e-04 caaatgttgc atttccca agaccag chr6:123911229-123911309 11 1.62e-04 TTACAGCTgg agtcccca acccccaggc chr2:96823550-96823630 45 1.62e-04 GGGTGGAGGA AGTTCCCT GCTGGGTCCA chr13:22614966-22615046 71 1.62e-04 catttcctgc atttccca ag chr12:31934980-31935060 69 1.62e-04 caaatgttgc atttccca agac chr11:95998676-95998756 66 1.62e-04 caaatgctac atttccca agaccac chr6:26071545-26071625 51 1.62e-04 caaatgttgc atttccca agacctcccc chr17:1090579-1090659 21 1.62e-04 CTTCAAGGCA AGTTCCCT CTGCAGTCCA chr2:209100743-209100823 39 1.62e-04 TTCTTCCTGT AGTTCCCT CTTTGGTCCT chr22:19654833-19654913 66 1.62e-04 caaatgttgc atttccca agaccac chr16:25377514-25377594 45 1.62e-04 TAATTTCTGT AGTCCCCA CTTAGGTCCG chr22:20177996-20178076 71 1.62e-04 atgttgtggc atttccca ag chr15:65544868-65544948 55 1.68e-04 CACCACATGC TGTTTTCA CTGGGGTCCT chr17:45820293-45820373 2 1.98e-04 C TGTCCTCT GCTGAGTCCT chr4:4997026-4997106 11 2.37e-04 GCAGCGGTGC TTTTCCCT CTGCATGAAG chr19:7939430-7939510 25 2.37e-04 GGGAAGCCTG TTTCCCCA GCTGCGCCTG chr3:52567027-52567107 52 2.37e-04 GTCCAACCGG TGTCCCCT TTGGTCCGGC chr10:75811921-75812001 42 2.70e-04 tgctttagct agtcctct atgtggtcca chr20:32777681-32777761 36 2.70e-04 TGGGAAGACC ATTCCTCA GCTCGGTCCG chr17:38059851-38059931 55 3.05e-04 TCTTCCCTGC AGTCCCCT GGGGGTGGAG chr8:24857567-24857647 17 3.05e-04 ATAGCCGCCA AGTCCCCT CCTGGGTACA chr6:106348579-106348659 12 3.53e-04 GATTAGCAGC TTTCCTCT GAGTCGGCCT chrX:55187716-55187796 10 3.53e-04 CGGCTCCTG TTTCCTCT GGGTCCGCCG chr19:10535017-10535097 54 3.53e-04 CGCTGGTCTC TGTCTCCA CTTGGGTCCT chr22:23145092-23145172 15 3.53e-04 GTGTGACTGA TGTTTCCT TTCAGGTCCA chr12:47475106-47475186 30 3.53e-04 TAGTGAAAGT TGTTTCCT ACATGGTCCG chr11:117923684-11792376 31 3.53e-04 tctgattctg tgtctcca aagcctacta chr17:72453431-72453511 71 3.81e-04 GTTTTTCTGT ATTTTTCA AG chr9:131938179-131938259 24 4.14e-04 CTTAGTGCAA AGTCTCCA ACGCAGTCGG chr10:29431558-29431638 60 4.14e-04 cggctgttgc attttcca agaccactgt chr21:45905313-45905393 64 4.14e-04 ccaatgttgc attttcca agaccaccc chr6:150262813-150262893 58 4.14e-04 GCCGCTGAAT ATTCCTCT GCAAGTTTCT chr11:78316560-78316640 69 4.14e-04 caaatgttgc attttcca agac chr2:798158-798238 59 4.36e-04 cagaagtgcc tgctctca cttaggtccg chr10:70884723-70884803 26 4.36e-04 GGGGAATCAG TGCTCTCA CCACAGTCCG chr17:27276555-27276635 51 4.76e-04 CCCTCCACGA TTTTTTCT ACAGCCACAA chr19:51611220-51611300 44 4.76e-04 gaatAATAAG TGCTCCCA GAAGAGAGGC chrX:18224950-18225030 4 4.76e-04 CTC TGCTCCCA GCTAAGCAGG chr9:136114363-136114443 9 5.22e-04 ATCCGCGG TCTTCCCA GTGGTCCTCT chr10:46762624-46762704 44 5.22e-04 CGACTCGCGA TCTTCCCA GTGCCCCAGA chr11:44797174-44797254 22 5.22e-04 CTGGGGCTGC TTTCTCCA GCGTCCGCCA chr5:55386103-55386183 33 5.65e-04 ggggcctcag agtcttct actgggtcct chr6:147370432-147370512 37 6.01e-04 ttgttgtggt agtctcct aactggtcct chr1:76229901-76229981 54 6.01e-04 caactgtatt agtctcct agggctgtca chr17:43129498-43129578 60 6.01e-04 GGAGCCATAA ATTTTCCT TTCCCCGGAG chr10:25233860-25233940 30 6.35e-04 cttcagcagc tgctctct ttcaagtcct chr12:31771690-31771770 39 6.35e-04 ggtcaaatcc tgctctct gttgggtcca chr13:22177776-22177856 68 7.06e-04 GTCCGCGGGG TTCTCCCA AGGGA chr9:127532796-127532876 66 7.06e-04 AGTGAGGGGA TGCCCCCA CTGACGG chr6:126656548-126656628 4 7.74e-04 cag tcttccct agagtccgca chr12:53278835-53278915 57 7.74e-04 AGCCTGCAAG TTTCTCCT AAGTTAGAAG chr22:37640310-37640390 29 7.74e-04 CTCAAGCTGC TCTCCCCA CGGTCGTTTG chr19:56915253-56915333 67 8.51e-04 CTGGTCCTCC AGCTCCCT TTTCTC chr5:139051259-139051339 45 8.51e-04 ACAGCTGCAG ACTTCTCT GCAACAGGGC chr19:4577494-4577574 43 8.51e-04 GTATTTGGGA AGCTCCCT CCTAGGTCCG chr19:6862967-6863047 19 8.51e-04 CGATAGCGCA ATCTCCCA GAGCGCTGGC chr7:116853135-116853215 32 8.51e-04 AAGTTGCCGC AGCTCCCT CTCAGGTCCG chr5:148064594-148064674 34 8.94e-04 CACCTTACTC TGCTTTCA ACAGGGTCCT chr6:155963922-155964002 53 8.94e-04 atgccttcaa tgctttca caggcaactc chrX:129091606-129091686 2 8.94e-04 G ACTTCCCT GGGGTCCGTT chr20:52509490-52509570 7 9.43e-04 attagc tgcttcca cttgggtcca chrX:9325965-9326045 57 9.43e-04 CCATCTGAGC TTCTCTCT AAGCCTGAAC chr9:102668730-102668810 9 1.01e-03 TGCGTCTC TCTCCTCT TGGCTCGAGT chr14:38065267-38065347 16 1.08e-03 GGTCCGCTCC TCTCCCCT TGTCATCTGT chr17:8030106-8030186 62 1.19e-03 TCCCTCCCGT TTCTTTCA ACCTGTTTTA chr19:50441138-50441218 65 1.50e-03 CTTCGAATAC AGTTCACA AAGCAGAC -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif WGTYCYCW MEME-3 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr8:128990129-128990209 8e-06 19_[+3]_53 chr12:117536600-11753668 1.9e-05 1_[+3]_71 chr7:44769174-44769254 1.9e-05 59_[+3]_13 chr21:21226155-21226235 2.8e-05 31_[+3]_41 chr2:219134646-219134726 2.8e-05 33_[+3]_39 chr1:31545316-31545396 2.8e-05 53_[+3]_19 chr12:83729602-83729682 2.8e-05 39_[+3]_33 chr1:16843346-16843426 4.1e-05 49_[+3]_23 chr19:35453901-35453981 4.1e-05 3_[+3]_69 chr14:101696610-10169669 6.5e-05 59_[+3]_13 chr9:90449760-90449840 6.5e-05 30_[+3]_42 chr8:12679331-12679411 6.5e-05 38_[+3]_34 chr20:25731126-25731206 6.5e-05 21_[+3]_51 chr10:134781278-13478135 6.5e-05 42_[+3]_30 chr8:140771215-140771295 6.5e-05 38_[+3]_34 chr18:48650652-48650732 6.5e-05 34_[+3]_38 chr11:102256247-10225632 6.5e-05 39_[+3]_33 chr22:19620468-19620548 6.5e-05 12_[+3]_60 chr22:19284516-19284596 6.5e-05 50_[+3]_22 chr16:3181995-3182075 6.5e-05 15_[+3]_57 chr1:94194417-94194497 6.5e-05 50_[+3]_22 chr5:38798121-38798201 9.9e-05 42_[+3]_30 chr16:88590140-88590220 9.9e-05 54_[+3]_18 chr1:85190192-85190272 9.9e-05 30_[+3]_42 chr17:17941976-17942056 9.9e-05 33_[+3]_39 chr21:44723906-44723986 0.00012 [+3]_72 chr22:21056768-21056848 0.00012 5_[+3]_67 chr7:140885523-140885603 0.00012 20_[+3]_52 chr12:117111634-11711171 0.00012 [+3]_72 chr1:31121414-31121494 0.00012 27_[+3]_45 chr11:111956692-11195677 0.00012 37_[+3]_35 chr8:11654674-11654754 0.00012 13_[+3]_59 chr19:4754410-4754490 0.00012 37_[+3]_35 chr12:15841327-15841407 0.00016 65_[+3]_7 chr6:123911229-123911309 0.00016 10_[+3]_62 chr2:96823550-96823630 0.00016 44_[+3]_28 chr13:22614966-22615046 0.00016 70_[+3]_2 chr12:31934980-31935060 0.00016 68_[+3]_4 chr11:95998676-95998756 0.00016 65_[+3]_7 chr6:26071545-26071625 0.00016 50_[+3]_22 chr17:1090579-1090659 0.00016 20_[+3]_52 chr2:209100743-209100823 0.00016 38_[+3]_34 chr22:19654833-19654913 0.00016 65_[+3]_7 chr16:25377514-25377594 0.00016 44_[+3]_28 chr22:20177996-20178076 0.00016 70_[+3]_2 chr15:65544868-65544948 0.00017 54_[+3]_18 chr17:45820293-45820373 0.0002 1_[+3]_71 chr4:4997026-4997106 0.00024 10_[+3]_62 chr19:7939430-7939510 0.00024 24_[+3]_48 chr3:52567027-52567107 0.00024 51_[+3]_21 chr10:75811921-75812001 0.00027 41_[+3]_31 chr20:32777681-32777761 0.00027 35_[+3]_37 chr17:38059851-38059931 0.00031 54_[+3]_18 chr8:24857567-24857647 0.00031 16_[+3]_56 chr6:106348579-106348659 0.00035 11_[+3]_61 chrX:55187716-55187796 0.00035 9_[+3]_63 chr19:10535017-10535097 0.00035 53_[+3]_19 chr22:23145092-23145172 0.00035 14_[+3]_58 chr12:47475106-47475186 0.00035 29_[+3]_43 chr11:117923684-11792376 0.00035 30_[+3]_42 chr17:72453431-72453511 0.00038 70_[+3]_2 chr9:131938179-131938259 0.00041 23_[+3]_49 chr10:29431558-29431638 0.00041 59_[+3]_13 chr21:45905313-45905393 0.00041 63_[+3]_9 chr6:150262813-150262893 0.00041 57_[+3]_15 chr11:78316560-78316640 0.00041 68_[+3]_4 chr2:798158-798238 0.00044 58_[+3]_14 chr10:70884723-70884803 0.00044 25_[+3]_47 chr17:27276555-27276635 0.00048 50_[+3]_22 chr19:51611220-51611300 0.00048 43_[+3]_29 chrX:18224950-18225030 0.00048 3_[+3]_69 chr9:136114363-136114443 0.00052 8_[+3]_64 chr10:46762624-46762704 0.00052 43_[+3]_29 chr11:44797174-44797254 0.00052 21_[+3]_51 chr5:55386103-55386183 0.00056 32_[+3]_40 chr6:147370432-147370512 0.0006 36_[+3]_36 chr1:76229901-76229981 0.0006 53_[+3]_19 chr17:43129498-43129578 0.0006 59_[+3]_13 chr10:25233860-25233940 0.00063 29_[+3]_43 chr12:31771690-31771770 0.00063 38_[+3]_34 chr13:22177776-22177856 0.00071 67_[+3]_5 chr9:127532796-127532876 0.00071 65_[+3]_7 chr6:126656548-126656628 0.00077 3_[+3]_69 chr12:53278835-53278915 0.00077 56_[+3]_16 chr22:37640310-37640390 0.00077 28_[+3]_44 chr19:56915253-56915333 0.00085 66_[+3]_6 chr5:139051259-139051339 0.00085 44_[+3]_28 chr19:4577494-4577574 0.00085 42_[+3]_30 chr19:6862967-6863047 0.00085 18_[+3]_54 chr7:116853135-116853215 0.00085 31_[+3]_41 chr5:148064594-148064674 0.00089 33_[+3]_39 chr6:155963922-155964002 0.00089 52_[+3]_20 chrX:129091606-129091686 0.00089 1_[+3]_71 chr20:52509490-52509570 0.00094 6_[+3]_66 chrX:9325965-9326045 0.00094 56_[+3]_16 chr9:102668730-102668810 0.001 8_[+3]_64 chr14:38065267-38065347 0.0011 15_[+3]_57 chr17:8030106-8030186 0.0012 61_[+3]_11 chr19:50441138-50441218 0.0015 64_[+3]_8 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif WGTYCYCW MEME-3 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF WGTYCYCW width=8 seqs=99 chr8:128990129-128990209 ( 20) TGTTCTCA 1 chr12:117536600-11753668 ( 2) TGTTCCCA 1 chr7:44769174-44769254 ( 60) TGTTCCCA 1 chr21:21226155-21226235 ( 32) AGTTCTCA 1 chr2:219134646-219134726 ( 34) AGTTCTCA 1 chr1:31545316-31545396 ( 54) AGTTCTCA 1 chr12:83729602-83729682 ( 40) AGTTCTCA 1 chr1:16843346-16843426 ( 50) AGTTCCCA 1 chr19:35453901-35453981 ( 4) AGTTCCCA 1 chr14:101696610-10169669 ( 60) TGTCCTCA 1 chr9:90449760-90449840 ( 31) TGTCCTCA 1 chr8:12679331-12679411 ( 39) TGTCCTCA 1 chr20:25731126-25731206 ( 22) TGTCCTCA 1 chr10:134781278-13478135 ( 43) TGTCCTCA 1 chr8:140771215-140771295 ( 39) TGTTCTCT 1 chr18:48650652-48650732 ( 35) TGTCCTCA 1 chr11:102256247-10225632 ( 40) TGTCCTCA 1 chr22:19620468-19620548 ( 13) TGTCCTCA 1 chr22:19284516-19284596 ( 51) TGTCCTCA 1 chr16:3181995-3182075 ( 16) TGTCCTCA 1 chr1:94194417-94194497 ( 51) TGTCCTCA 1 chr5:38798121-38798201 ( 43) TGTCCCCA 1 chr16:88590140-88590220 ( 55) TGTTCCCT 1 chr1:85190192-85190272 ( 31) TGTTCCCT 1 chr17:17941976-17942056 ( 34) TGTTCCCT 1 chr21:44723906-44723986 ( 1) AGTCCTCA 1 chr22:21056768-21056848 ( 6) AGTCCTCA 1 chr7:140885523-140885603 ( 21) AGTCCTCA 1 chr12:117111634-11711171 ( 1) AGTCCTCA 1 chr1:31121414-31121494 ( 28) AGTCCTCA 1 chr11:111956692-11195677 ( 38) AGTTCTCT 1 chr8:11654674-11654754 ( 14) AGTCCTCA 1 chr19:4754410-4754490 ( 38) AGTCCTCA 1 chr12:15841327-15841407 ( 66) ATTTCCCA 1 chr6:123911229-123911309 ( 11) AGTCCCCA 1 chr2:96823550-96823630 ( 45) AGTTCCCT 1 chr13:22614966-22615046 ( 71) ATTTCCCA 1 chr12:31934980-31935060 ( 69) ATTTCCCA 1 chr11:95998676-95998756 ( 66) ATTTCCCA 1 chr6:26071545-26071625 ( 51) ATTTCCCA 1 chr17:1090579-1090659 ( 21) AGTTCCCT 1 chr2:209100743-209100823 ( 39) AGTTCCCT 1 chr22:19654833-19654913 ( 66) ATTTCCCA 1 chr16:25377514-25377594 ( 45) AGTCCCCA 1 chr22:20177996-20178076 ( 71) ATTTCCCA 1 chr15:65544868-65544948 ( 55) TGTTTTCA 1 chr17:45820293-45820373 ( 2) TGTCCTCT 1 chr4:4997026-4997106 ( 11) TTTTCCCT 1 chr19:7939430-7939510 ( 25) TTTCCCCA 1 chr3:52567027-52567107 ( 52) TGTCCCCT 1 chr10:75811921-75812001 ( 42) AGTCCTCT 1 chr20:32777681-32777761 ( 36) ATTCCTCA 1 chr17:38059851-38059931 ( 55) AGTCCCCT 1 chr8:24857567-24857647 ( 17) AGTCCCCT 1 chr6:106348579-106348659 ( 12) TTTCCTCT 1 chrX:55187716-55187796 ( 10) TTTCCTCT 1 chr19:10535017-10535097 ( 54) TGTCTCCA 1 chr22:23145092-23145172 ( 15) TGTTTCCT 1 chr12:47475106-47475186 ( 30) TGTTTCCT 1 chr11:117923684-11792376 ( 31) TGTCTCCA 1 chr17:72453431-72453511 ( 71) ATTTTTCA 1 chr9:131938179-131938259 ( 24) AGTCTCCA 1 chr10:29431558-29431638 ( 60) ATTTTCCA 1 chr21:45905313-45905393 ( 64) ATTTTCCA 1 chr6:150262813-150262893 ( 58) ATTCCTCT 1 chr11:78316560-78316640 ( 69) ATTTTCCA 1 chr2:798158-798238 ( 59) TGCTCTCA 1 chr10:70884723-70884803 ( 26) TGCTCTCA 1 chr17:27276555-27276635 ( 51) TTTTTTCT 1 chr19:51611220-51611300 ( 44) TGCTCCCA 1 chrX:18224950-18225030 ( 4) TGCTCCCA 1 chr9:136114363-136114443 ( 9) TCTTCCCA 1 chr10:46762624-46762704 ( 44) TCTTCCCA 1 chr11:44797174-44797254 ( 22) TTTCTCCA 1 chr5:55386103-55386183 ( 33) AGTCTTCT 1 chr6:147370432-147370512 ( 37) AGTCTCCT 1 chr1:76229901-76229981 ( 54) AGTCTCCT 1 chr17:43129498-43129578 ( 60) ATTTTCCT 1 chr10:25233860-25233940 ( 30) TGCTCTCT 1 chr12:31771690-31771770 ( 39) TGCTCTCT 1 chr13:22177776-22177856 ( 68) TTCTCCCA 1 chr9:127532796-127532876 ( 66) TGCCCCCA 1 chr6:126656548-126656628 ( 4) TCTTCCCT 1 chr12:53278835-53278915 ( 57) TTTCTCCT 1 chr22:37640310-37640390 ( 29) TCTCCCCA 1 chr19:56915253-56915333 ( 67) AGCTCCCT 1 chr5:139051259-139051339 ( 45) ACTTCTCT 1 chr19:4577494-4577574 ( 43) AGCTCCCT 1 chr19:6862967-6863047 ( 19) ATCTCCCA 1 chr7:116853135-116853215 ( 32) AGCTCCCT 1 chr5:148064594-148064674 ( 34) TGCTTTCA 1 chr6:155963922-155964002 ( 53) TGCTTTCA 1 chrX:129091606-129091686 ( 2) ACTTCCCT 1 chr20:52509490-52509570 ( 7) TGCTTCCA 1 chrX:9325965-9326045 ( 57) TTCTCTCT 1 chr9:102668730-102668810 ( 9) TCTCCTCT 1 chr14:38065267-38065347 ( 16) TCTCCCCT 1 chr17:8030106-8030186 ( 62) TTCTTTCA 1 chr19:50441138-50441218 ( 65) AGTTCACA 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif WGTYCYCW MEME-3 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 8.6474 E= 1.0e-020 115 -1327 -1327 141 -1327 -180 113 35 -1327 -72 -1327 207 -1327 62 -1327 152 -1327 148 -1327 10 -441 92 -1327 120 -1327 182 -1327 -1327 157 -1327 -1327 88 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif WGTYCYCW MEME-3 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 99 E= 1.0e-020 0.474747 0.000000 0.000000 0.525253 0.000000 0.080808 0.666667 0.252525 0.000000 0.171717 0.000000 0.828283 0.000000 0.434343 0.000000 0.565657 0.000000 0.787879 0.000000 0.212121 0.010101 0.535354 0.000000 0.454545 0.000000 1.000000 0.000000 0.000000 0.636364 0.000000 0.000000 0.363636 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif WGTYCYCW MEME-3 regular expression -------------------------------------------------------------------------------- [TA][GT]T[TC][CT][CT]C[AT] -------------------------------------------------------------------------------- Time 12.16 secs. ******************************************************************************** ******************************************************************************** MOTIF MVCGGACC MEME-4 width = 8 sites = 47 llr = 384 E-value = 8.1e-011 ******************************************************************************** -------------------------------------------------------------------------------- Motif MVCGGACC MEME-4 Description -------------------------------------------------------------------------------- Simplified A 43:::a:: pos.-specific C 648:::aa probability G :3:aa::: matrix T ::2::::: bits 2.3 2.1 * 1.9 *** 1.6 ***** Relative 1.4 ***** Entropy 1.2 ****** (11.8 bits) 0.9 * ****** 0.7 * ****** 0.5 * ****** 0.2 ******** 0.0 -------- Multilevel CCCGGACC consensus AAT sequence G -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif MVCGGACC MEME-4 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr6:123911229-123911309 29 2.72e-05 acccccaggc cacggacc cattaggaac chr12:31934980-31935060 26 2.72e-05 gctccacccc cacggacc taggtgagga chr7:44769174-44769254 38 2.72e-05 tggataaatc cacggacc agattgagaa chr19:39470683-39470763 42 2.72e-05 cagataaatc cacggacc agattgagaa chr11:95998676-95998756 16 2.72e-05 actccacccc cacggacc taggtgagga chr17:42706268-42706348 27 2.72e-05 gctccacccc cacggacc taggtgagga chr10:46762624-46762704 64 2.72e-05 GCCCCAGAGC CACGGACC CAACCGCCG chr22:19654833-19654913 16 2.72e-05 gctccacccc cacggacc taggtgagga chr2:145290968-145291048 29 2.72e-05 acccccaggc cacggacc cgtgaggaac chr13:28404156-28404236 60 2.72e-05 CCGCAGGCCC CACGGACC CAGGAGAGGC chr11:78316560-78316640 19 2.72e-05 gctccacccc cacggacc taggtgagga chr4:48271553-48271633 26 8.36e-05 GTCCCTCCTT CCCGGACC GAAGAGGGGA chr19:17420576-17420656 43 8.36e-05 ACCTTCGACC CCCGGACC CTACCGAGAG chr21:45905313-45905393 14 8.36e-05 gctccacccc cccggacc tgggtgagga chr2:201520820-201520900 31 8.36e-05 TGCAGGCTTT CCCGGACC ACAGTGGAAC chr4:1748109-1748189 54 1.11e-04 CCATGCAGGG ACCGGACC AGGTGGGTGA chr6:12200299-12200379 53 1.11e-04 gggctcagac accggacc agattgagga chr22:25518143-25518223 21 1.11e-04 gggctcgggc accggacc acattgagga chr7:49997-50077 61 1.11e-04 gggctcgaac accggacc agattgagga chrX:133282436-133282516 41 1.11e-04 gggcttggac accggacc agattgagga chr6:137092481-137092561 18 1.11e-04 gggcttggac accggacc agattgagga chrX:150067418-150067498 46 1.49e-04 GAGGTGGCCC CGCGGACC TGGAGCAGTG chr10:81664549-81664629 49 1.49e-04 TCCGGAGGCA CGCGGACC CGGTGGAACG chr22:39151552-39151632 62 1.49e-04 GGGCGCGGGC CGCGGACC CGGGTGGAGG chr19:51611220-51611300 62 1.49e-04 GAAGAGAGGC CGCGGACC CCAGGGATGC chr14:97230499-97230579 23 1.49e-04 ctcataggag cgcggacc ctattgagaa chr6:150262813-150262893 15 1.49e-04 GGGAGAGCGT CGCGGACC CAGGCGGGGA chr1:10062964-10063044 43 1.79e-04 ggcttgggac agcggacc aaactgagga chr16:46588463-46588543 39 1.79e-04 cccgttgaca agcggacc gtggtctggc chr10:3826970-3827050 42 1.79e-04 GCCCAGGCCC AGCGGACC GCAGAGAGCA chr5:70882362-70882442 50 1.79e-04 acaatgtggg agcggacc gagcagagct chr19:1725440-1725520 51 1.79e-04 TCCAGGATAC AGCGGACC CCGATGAAGC chr21:47645252-47645332 37 1.79e-04 cccgttgcca agcggacc caaccgtggt chr9:102582843-102582923 52 1.79e-04 TTGTGATTCA AGCGGACC ACATGGGGAC chr9:35574734-35574814 39 1.79e-04 agggctcagc agcggacc aaattgagga chr9:139661103-139661183 7 1.79e-04 ttgcca agcggacc gtgatctagc chr12:15841327-15841407 16 1.98e-04 gctccacccc catggacc tagatgagga chr13:22614966-22615046 30 1.98e-04 gctctacccc catggacc taggtgagga chr22:20177996-20178076 25 1.98e-04 gttccacccc catggacc taggtgagga chr13:21585018-21585098 16 2.12e-04 catttgcata aatggacc tgagtgagaa chr16:85309295-85309375 42 2.37e-04 CGCGTGGGGC CCTGGACC CAGGTGGAAA chr8:101446339-101446419 58 2.37e-04 TTATCAAAGT CCTGGACC AGAGGGAGAA chr10:75811921-75812001 24 2.37e-04 gtgcttttac cctggacc tgctttagct chr22:39615446-39615526 43 2.57e-04 aagactcgac actggacc agattgagga chr19:35867095-35867175 28 2.57e-04 gggctcagac actggacc aaattgagga chr3:69745620-69745700 46 2.57e-04 gggcttggac actggacc aaattgagga chr19:40037379-40037459 18 2.57e-04 gggcttggac actggacc agactgaaga -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif MVCGGACC MEME-4 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr6:123911229-123911309 2.7e-05 28_[+4]_44 chr12:31934980-31935060 2.7e-05 25_[+4]_47 chr7:44769174-44769254 2.7e-05 37_[+4]_35 chr19:39470683-39470763 2.7e-05 41_[+4]_31 chr11:95998676-95998756 2.7e-05 15_[+4]_57 chr17:42706268-42706348 2.7e-05 26_[+4]_46 chr10:46762624-46762704 2.7e-05 63_[+4]_9 chr22:19654833-19654913 2.7e-05 15_[+4]_57 chr2:145290968-145291048 2.7e-05 28_[+4]_44 chr13:28404156-28404236 2.7e-05 59_[+4]_13 chr11:78316560-78316640 2.7e-05 18_[+4]_54 chr4:48271553-48271633 8.4e-05 25_[+4]_47 chr19:17420576-17420656 8.4e-05 42_[+4]_30 chr21:45905313-45905393 8.4e-05 13_[+4]_59 chr2:201520820-201520900 8.4e-05 30_[+4]_42 chr4:1748109-1748189 0.00011 53_[+4]_19 chr6:12200299-12200379 0.00011 52_[+4]_20 chr22:25518143-25518223 0.00011 20_[+4]_52 chr7:49997-50077 0.00011 60_[+4]_12 chrX:133282436-133282516 0.00011 40_[+4]_32 chr6:137092481-137092561 0.00011 17_[+4]_55 chrX:150067418-150067498 0.00015 45_[+4]_27 chr10:81664549-81664629 0.00015 48_[+4]_24 chr22:39151552-39151632 0.00015 61_[+4]_11 chr19:51611220-51611300 0.00015 61_[+4]_11 chr14:97230499-97230579 0.00015 22_[+4]_50 chr6:150262813-150262893 0.00015 14_[+4]_58 chr1:10062964-10063044 0.00018 42_[+4]_30 chr16:46588463-46588543 0.00018 38_[+4]_34 chr10:3826970-3827050 0.00018 41_[+4]_31 chr5:70882362-70882442 0.00018 49_[+4]_23 chr19:1725440-1725520 0.00018 50_[+4]_22 chr21:47645252-47645332 0.00018 36_[+4]_36 chr9:102582843-102582923 0.00018 51_[+4]_21 chr9:35574734-35574814 0.00018 38_[+4]_34 chr9:139661103-139661183 0.00018 6_[+4]_66 chr12:15841327-15841407 0.0002 15_[+4]_57 chr13:22614966-22615046 0.0002 29_[+4]_43 chr22:20177996-20178076 0.0002 24_[+4]_48 chr13:21585018-21585098 0.00021 15_[+4]_57 chr16:85309295-85309375 0.00024 41_[+4]_31 chr8:101446339-101446419 0.00024 57_[+4]_15 chr10:75811921-75812001 0.00024 23_[+4]_49 chr22:39615446-39615526 0.00026 42_[+4]_30 chr19:35867095-35867175 0.00026 27_[+4]_45 chr3:69745620-69745700 0.00026 45_[+4]_27 chr19:40037379-40037459 0.00026 17_[+4]_55 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif MVCGGACC MEME-4 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF MVCGGACC width=8 seqs=47 chr6:123911229-123911309 ( 29) CACGGACC 1 chr12:31934980-31935060 ( 26) CACGGACC 1 chr7:44769174-44769254 ( 38) CACGGACC 1 chr19:39470683-39470763 ( 42) CACGGACC 1 chr11:95998676-95998756 ( 16) CACGGACC 1 chr17:42706268-42706348 ( 27) CACGGACC 1 chr10:46762624-46762704 ( 64) CACGGACC 1 chr22:19654833-19654913 ( 16) CACGGACC 1 chr2:145290968-145291048 ( 29) CACGGACC 1 chr13:28404156-28404236 ( 60) CACGGACC 1 chr11:78316560-78316640 ( 19) CACGGACC 1 chr4:48271553-48271633 ( 26) CCCGGACC 1 chr19:17420576-17420656 ( 43) CCCGGACC 1 chr21:45905313-45905393 ( 14) CCCGGACC 1 chr2:201520820-201520900 ( 31) CCCGGACC 1 chr4:1748109-1748189 ( 54) ACCGGACC 1 chr6:12200299-12200379 ( 53) ACCGGACC 1 chr22:25518143-25518223 ( 21) ACCGGACC 1 chr7:49997-50077 ( 61) ACCGGACC 1 chrX:133282436-133282516 ( 41) ACCGGACC 1 chr6:137092481-137092561 ( 18) ACCGGACC 1 chrX:150067418-150067498 ( 46) CGCGGACC 1 chr10:81664549-81664629 ( 49) CGCGGACC 1 chr22:39151552-39151632 ( 62) CGCGGACC 1 chr19:51611220-51611300 ( 62) CGCGGACC 1 chr14:97230499-97230579 ( 23) CGCGGACC 1 chr6:150262813-150262893 ( 15) CGCGGACC 1 chr1:10062964-10063044 ( 43) AGCGGACC 1 chr16:46588463-46588543 ( 39) AGCGGACC 1 chr10:3826970-3827050 ( 42) AGCGGACC 1 chr5:70882362-70882442 ( 50) AGCGGACC 1 chr19:1725440-1725520 ( 51) AGCGGACC 1 chr21:47645252-47645332 ( 37) AGCGGACC 1 chr9:102582843-102582923 ( 52) AGCGGACC 1 chr9:35574734-35574814 ( 39) AGCGGACC 1 chr9:139661103-139661183 ( 7) AGCGGACC 1 chr12:15841327-15841407 ( 16) CATGGACC 1 chr13:22614966-22615046 ( 30) CATGGACC 1 chr22:20177996-20178076 ( 25) CATGGACC 1 chr13:21585018-21585098 ( 16) AATGGACC 1 chr16:85309295-85309375 ( 42) CCTGGACC 1 chr8:101446339-101446419 ( 58) CCTGGACC 1 chr10:75811921-75812001 ( 24) CCTGGACC 1 chr22:39615446-39615526 ( 43) ACTGGACC 1 chr19:35867095-35867175 ( 28) ACTGGACC 1 chr3:69745620-69745700 ( 46) ACTGGACC 1 chr19:40037379-40037459 ( 18) ACTGGACC 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif MVCGGACC MEME-4 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 8.22956 E= 8.1e-011 99 102 -1220 -1220 57 36 6 -1220 -1220 144 -1220 24 -1220 -1220 171 -1220 -1220 -1220 171 -1220 222 -1220 -1220 -1220 -1220 182 -1220 -1220 -1220 182 -1220 -1220 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif MVCGGACC MEME-4 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 47 E= 8.1e-011 0.425532 0.574468 0.000000 0.000000 0.319149 0.361702 0.319149 0.000000 0.000000 0.765957 0.000000 0.234043 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif MVCGGACC MEME-4 regular expression -------------------------------------------------------------------------------- [CA][CAG][CT]GGACC -------------------------------------------------------------------------------- Time 15.50 secs. ******************************************************************************** ******************************************************************************** MOTIF CAACATTT MEME-5 width = 8 sites = 8 llr = 96 E-value = 3.9e-002 ******************************************************************************** -------------------------------------------------------------------------------- Motif CAACATTT MEME-5 Description -------------------------------------------------------------------------------- Simplified A :aa:a::: pos.-specific C a::a:::: probability G :::::::: matrix T :::::aaa bits 2.3 *** 2.1 ** **** 1.9 ******** 1.6 ******** Relative 1.4 ******** Entropy 1.2 ******** (17.3 bits) 0.9 ******** 0.7 ******** 0.5 ******** 0.2 ******** 0.0 -------- Multilevel CAACATTT consensus sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CAACATTT MEME-5 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr5:38798121-38798201 14 6.13e-06 ctggaaaatg caacattt gagcaggaat chr9:90449760-90449840 2 6.13e-06 a caacattt gggcactgaa chr8:12679331-12679411 10 6.13e-06 tgggaaatg caacattt gggcaggaag chr10:134781278-13478135 21 6.13e-06 ttgggaaatg caacattt aggcaggaaa chr18:48650652-48650732 12 6.13e-06 ttggggaatg caacattt gggcagaaaa chr11:102256247-10225632 11 6.13e-06 ttgggaaatg caacattt ggggaggaaa chr22:19284516-19284596 29 6.13e-06 ttgagaaata caacattt gggcagaaaa chr1:94194417-94194497 22 6.13e-06 ttgggaaatg caacattt gggcaggaaa -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CAACATTT MEME-5 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr5:38798121-38798201 6.1e-06 13_[+5]_59 chr9:90449760-90449840 6.1e-06 1_[+5]_71 chr8:12679331-12679411 6.1e-06 9_[+5]_63 chr10:134781278-13478135 6.1e-06 20_[+5]_52 chr18:48650652-48650732 6.1e-06 11_[+5]_61 chr11:102256247-10225632 6.1e-06 10_[+5]_62 chr22:19284516-19284596 6.1e-06 28_[+5]_44 chr1:94194417-94194497 6.1e-06 21_[+5]_51 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CAACATTT MEME-5 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF CAACATTT width=8 seqs=8 chr5:38798121-38798201 ( 14) CAACATTT 1 chr9:90449760-90449840 ( 2) CAACATTT 1 chr8:12679331-12679411 ( 10) CAACATTT 1 chr10:134781278-13478135 ( 21) CAACATTT 1 chr18:48650652-48650732 ( 12) CAACATTT 1 chr11:102256247-10225632 ( 11) CAACATTT 1 chr22:19284516-19284596 ( 29) CAACATTT 1 chr1:94194417-94194497 ( 22) CAACATTT 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CAACATTT MEME-5 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 11.155 E= 3.9e-002 -965 182 -965 -965 222 -965 -965 -965 222 -965 -965 -965 -965 182 -965 -965 222 -965 -965 -965 -965 -965 -965 234 -965 -965 -965 234 -965 -965 -965 234 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CAACATTT MEME-5 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 8 E= 3.9e-002 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CAACATTT MEME-5 regular expression -------------------------------------------------------------------------------- CAACATTT -------------------------------------------------------------------------------- Time 18.76 secs. ******************************************************************************** ******************************************************************************** SUMMARY OF MOTIFS ******************************************************************************** -------------------------------------------------------------------------------- Combined block diagrams: non-overlapping sites with p-value < 0.0001 -------------------------------------------------------------------------------- SEQUENCE NAME COMBINED P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr19:4754410-4754490 8.87e-03 48_[+2(8.86e-05)]_24 chr19:35453901-35453981 1.52e-02 3_[+3(4.05e-05)]_69 chr1:94194417-94194497 1.56e-05 21_[+5(6.13e-06)]_21_[+3(6.45e-05)]_\ 3_[+2(8.86e-05)]_11 chr11:78316560-78316640 2.04e-04 18_[+4(2.72e-05)]_4_[+1(5.09e-05)]_\ 42 chr17:72453431-72453511 7.64e-04 32_[+1(3.52e-05)]_4_[+1(5.09e-05)]_\ 28 chr17:41392947-41393027 6.40e-01 80 chr8:23365264-23365344 1.35e-01 80 chr16:3181995-3182075 2.22e-02 15_[+3(6.45e-05)]_57 chr11:106047619-10604769 1.45e-02 57_[+1(5.09e-05)]_15 chr5:145921992-145922072 4.63e-02 52_[+2(8.86e-05)]_20 chr8:11654674-11654754 6.99e-02 80 chr13:28404156-28404236 7.52e-02 59_[+4(2.72e-05)]_13 chr22:19284516-19284596 6.44e-06 28_[+5(6.13e-06)]_14_[+3(6.45e-05)]_\ 3_[+2(8.86e-05)]_11 chr22:19620468-19620548 7.39e-03 12_[+3(6.45e-05)]_3_[+2(8.86e-05)]_\ 49 chr22:20177996-20178076 2.64e-04 36_[+1(5.09e-05)]_36 chr20:32777681-32777761 6.33e-03 80 chr7:116853135-116853215 2.91e-02 42_[+2(5.20e-05)]_30 chr16:25377514-25377594 1.46e-02 55_[+2(8.86e-05)]_17 chr6:150262813-150262893 1.55e-02 80 chr12:31771690-31771770 9.98e-02 80 chr5:180497157-180497237 2.90e-01 80 chr6:137092481-137092561 3.06e-03 29_[+1(1.45e-05)]_43 chr2:145290968-145291048 1.47e-03 28_[+4(2.72e-05)]_44 chr14:97230499-97230579 2.03e-02 80 chr9:130266400-130266480 3.82e-01 80 chr11:117923684-11792376 1.03e-01 80 chr11:44797174-44797254 6.29e-02 80 chr11:111956692-11195677 1.52e-02 80 chr18:33656451-33656531 5.73e-04 30_[+1(1.45e-05)]_42 chr1:156130734-156130814 8.36e-01 80 chr4:138827264-138827344 1.28e-01 80 chr18:711522-711602 6.30e-02 43_[+1(3.52e-05)]_29 chr12:83729602-83729682 3.58e-02 39_[+3(2.81e-05)]_33 chr5:10539849-10539929 8.41e-02 80 chr9:139661103-139661183 6.70e-02 80 chr20:61406313-61406393 9.20e-03 22_[+1(3.52e-05)]_50 chr17:17941976-17942056 2.03e-01 33_[+3(9.87e-05)]_39 chr1:31121414-31121494 1.23e-02 80 chr2:61293674-61293754 1.41e-01 80 chr22:19654833-19654913 9.85e-05 15_[+4(2.72e-05)]_4_[+1(5.09e-05)]_\ 45 chr20:45967183-45967263 3.22e-01 80 chr17:8030106-8030186 2.28e-01 80 chr10:70884723-70884803 1.88e-01 80 chr14:21150683-21150763 2.67e-01 80 chr10:46762624-46762704 5.70e-04 63_[+4(2.72e-05)]_9 chr8:101804306-101804386 2.40e-01 14_[+2(5.20e-05)]_58 chr10:75811921-75812001 2.85e-02 80 chr9:134638101-134638181 5.69e-01 80 chr8:80673391-80673471 1.36e-02 80 chr17:42706268-42706348 5.49e-04 26_[+4(2.72e-05)]_4_[+1(5.09e-05)]_\ 34 chr6:43061687-43061767 3.41e-01 80 chrX:18224950-18225030 4.06e-01 80 chr8:24857567-24857647 3.44e-01 80 chr2:209100743-209100823 2.58e-02 80 chrX:133282436-133282516 1.20e-03 52_[+1(1.45e-05)]_20 chr3:52567027-52567107 5.61e-03 80 chr9:127532796-127532876 1.75e-01 80 chr19:40037379-40037459 5.91e-03 80 chr8:79428398-79428478 8.91e-01 80 chr12:56561977-56562057 2.47e-01 80 chr5:150428237-150428317 1.50e-01 80 chr11:102256247-10225632 6.04e-06 10_[+5(6.13e-06)]_21_[+3(6.45e-05)]_\ 3_[+2(8.86e-05)]_22 chr2:201520820-201520900 8.02e-03 30_[+4(8.36e-05)]_42 chr9:35574734-35574814 6.26e-03 50_[+1(1.45e-05)]_22 chr19:7939430-7939510 3.15e-03 80 chr12:47475106-47475186 4.96e-03 40_[+2(8.86e-05)]_32 chr19:33166405-33166485 4.32e-01 80 chr17:1090579-1090659 3.06e-01 80 chr9:136114363-136114443 2.12e-02 80 chr15:43806610-43806690 3.64e-01 80 chr16:89573979-89574059 6.41e-02 80 chr6:26071545-26071625 9.65e-04 12_[+1(5.09e-05)]_60 chr16:85762575-85762655 1.35e-03 51_[+4(8.36e-05)]_21 chr11:95998676-95998756 6.16e-06 15_[+4(2.72e-05)]_4_[+1(5.09e-05)]_\ 45 chr22:37374198-37374278 2.03e-01 80 chr1:31545316-31545396 1.92e-02 53_[+3(2.81e-05)]_19 chr19:51611220-51611300 3.89e-02 80 chr22:39151552-39151632 2.39e-01 80 chr11:117680117-11768019 3.38e-01 80 chr9:131465419-131465499 4.06e-01 80 chr10:81664549-81664629 6.99e-02 80 chrX:24483055-24483135 1.35e-01 80 chrX:9325965-9326045 1.65e-01 80 chr3:52568028-52568108 6.95e-01 80 chr22:30304121-30304201 4.33e-02 80 chr17:43129498-43129578 1.17e-02 80 chr21:45905313-45905393 4.10e-04 13_[+4(8.36e-05)]_4_[+1(5.09e-05)]_\ 47 chr1:205735872-205735952 2.90e-02 10_[+1(3.52e-05)]_62 chr12:51611008-51611088 8.53e-02 51_[+2(5.20e-05)]_21 chr2:106286084-106286164 1.83e-01 80 chr19:39470683-39470763 4.93e-03 41_[+4(2.72e-05)]_31 chr15:58357247-58357327 1.42e-01 80 chr1:47981231-47981311 5.91e-01 80 chr11:3663413-3663493 5.83e-01 80 chr17:37024583-37024663 1.10e-01 80 chr8:29197828-29197908 2.34e-01 80 chr9:102582843-102582923 2.92e-02 80 chr16:86794817-86794897 2.60e-01 37_[+1(7.32e-05)]_4_[+1(7.32e-05)]_\ 23 chr22:37640310-37640390 2.60e-01 80 chr16:3151494-3151574 5.08e-01 80 chr19:1203120-1203200 4.63e-02 80 chr4:4997026-4997106 1.51e-01 80 chr12:117111634-11711171 1.98e-01 80 chr7:44769174-44769254 3.92e-05 37_[+4(2.72e-05)]_14_[+3(1.94e-05)]_\ 13 chr4:1595675-1595755 6.41e-01 80 chr19:17420576-17420656 1.04e-02 42_[+4(8.36e-05)]_30 chr21:47645252-47645332 1.70e-02 80 chr5:42909192-42909272 1.32e-01 80 chr14:38065267-38065347 3.30e-02 80 chr1:16843346-16843426 4.64e-02 49_[+3(4.05e-05)]_23 chr17:7589421-7589501 4.70e-02 80 chr12:31934980-31935060 8.27e-06 25_[+4(2.72e-05)]_4_[+1(5.09e-05)]_\ 35 chr17:75275996-75276076 6.27e-01 80 chr22:23145092-23145172 8.77e-02 80 chr17:79643123-79643203 8.67e-02 80 chr3:183872880-183872960 9.32e-02 80 chr8:101446339-101446419 2.19e-02 80 chr17:79375987-79376067 2.00e-02 80 chr17:45820293-45820373 3.41e-02 80 chr16:1429929-1430009 2.15e-01 80 chr2:219134646-219134726 3.04e-04 33_[+3(2.81e-05)]_39 chr5:55386103-55386183 5.63e-02 80 chr8:91251826-91251906 2.13e-01 80 chr5:42757485-42757565 1.00e-01 80 chr8:142034530-142034610 1.15e-01 57_[+1(1.45e-05)]_15 chr12:58160755-58160835 3.89e-01 80 chr13:22614966-22615046 1.54e-05 41_[+1(5.09e-05)]_31 chr10:25233860-25233940 4.41e-01 80 chr8:145100883-145100963 2.26e-01 80 chr18:48650652-48650732 1.24e-06 11_[+5(6.13e-06)]_15_[+3(6.45e-05)]_\ 3_[+2(8.86e-05)]_27 chr17:27276555-27276635 2.14e-02 80 chr7:49997-50077 4.71e-03 72_[+1(1.45e-05)] chr19:1725440-1725520 1.25e-01 80 chr20:52509490-52509570 1.15e-01 80 chr21:21226155-21226235 2.09e-02 31_[+3(2.81e-05)]_41 chr6:29945138-29945218 8.08e-01 80 chr19:10535017-10535097 8.59e-02 80 chr3:69745620-69745700 8.96e-03 57_[+1(1.45e-05)]_15 chr4:1875218-1875298 1.41e-01 80 chr19:6862967-6863047 2.25e-01 80 chr20:47936099-47936179 2.25e-01 62_[+2(5.20e-05)]_10 chr8:128990129-128990209 2.51e-02 19_[+3(8.01e-06)]_53 chr7:156741646-156741726 4.55e-02 25_[+2(8.86e-05)]_47 chr2:798158-798238 5.25e-04 69_[+2(8.86e-05)]_3 chr19:39988697-39988777 8.86e-01 80 chr22:37415792-37415872 2.35e-02 10_[+2(5.20e-05)]_62 chr8:140771215-140771295 4.80e-03 38_[+3(6.45e-05)]_3_[+2(5.20e-05)]_\ 23 chr12:53278835-53278915 6.96e-02 80 chr11:59521659-59521739 4.55e-01 80 chr19:35867095-35867175 8.43e-03 39_[+1(1.45e-05)]_33 chr7:75368066-75368146 4.51e-01 80 chr12:128476112-12847619 6.14e-02 80 chr16:58059527-58059607 9.69e-02 80 chr1:76229901-76229981 3.79e-02 80 chr6:24659290-24659370 3.19e-01 80 chr16:88850650-88850730 2.72e-02 80 chr17:6478701-6478781 3.01e-01 80 chrX:55187716-55187796 3.52e-02 80 chr6:1554079-1554159 1.65e-01 34_[+1(7.32e-05)]_38 chr19:2785901-2785981 5.31e-02 80 chr2:12858477-12858557 7.69e-03 46_[+2(5.20e-05)]_26 chr5:70882362-70882442 2.53e-02 80 chr13:21585018-21585098 6.33e-03 80 chr1:93250595-93250675 3.64e-01 80 chr2:32583211-32583291 5.24e-02 80 chr22:25518143-25518223 1.56e-03 32_[+1(1.45e-05)]_40 chr2:171571274-171571354 8.06e-01 80 chr4:48271553-48271633 4.47e-02 25_[+4(8.36e-05)]_47 chr5:176981055-176981135 5.57e-02 80 chr21:36261657-36261737 6.15e-01 80 chr10:134781278-13478135 2.07e-05 20_[+5(6.13e-06)]_14_[+3(6.45e-05)]_\ 3_[+2(8.86e-05)]_19 chr20:25731126-25731206 2.62e-04 21_[+3(6.45e-05)]_3_[+2(8.86e-05)]_\ 40 chr19:4577494-4577574 9.60e-03 53_[+2(5.20e-05)]_19 chr11:117688468-11768854 1.61e-01 80 chr8:144660853-144660933 1.26e-01 80 chrX:1999917-1999997 8.85e-01 80 chr7:39454123-39454203 2.40e-01 80 chr1:55353084-55353164 3.16e-01 80 chr19:54693434-54693514 4.23e-01 80 chr5:139051259-139051339 3.82e-02 80 chr2:96823550-96823630 7.40e-02 80 chr10:29431558-29431638 5.19e-03 24_[+1(5.09e-05)]_48 chr19:44278394-44278474 1.41e-01 80 chr17:73266607-73266687 7.13e-01 80 chr8:12679331-12679411 2.07e-05 9_[+5(6.13e-06)]_21_[+3(6.45e-05)]_\ 3_[+2(8.86e-05)]_23 chr1:85190192-85190272 3.17e-02 30_[+3(9.87e-05)]_42 chrX:129091606-129091686 7.72e-02 80 chr6:123911229-123911309 7.01e-03 28_[+4(2.72e-05)]_44 chr13:22177776-22177856 1.89e-01 80 chr9:131938179-131938259 4.82e-02 80 chr6:147370432-147370512 2.27e-02 80 chr8:142139648-142139728 5.16e-02 48_[+2(5.20e-05)]_24 chr15:65544868-65544948 4.39e-02 80 chr7:140885523-140885603 1.17e-03 80 chr19:46080579-46080659 3.06e-01 80 chr7:137910866-137910946 3.58e-02 80 chr6:12200299-12200379 3.17e-03 64_[+1(1.45e-05)]_8 chr10:3826970-3827050 9.57e-02 80 chr16:1327998-1328078 1.40e-01 80 chr12:117536600-11753668 2.56e-04 1_[+3(1.94e-05)]_3_[+2(5.20e-05)]_\ 60 chr5:150537318-150537398 8.68e-02 80 chr22:21056768-21056848 4.78e-02 80 chr16:46588463-46588543 2.48e-02 80 chr15:41245825-41245905 6.75e-01 80 chr20:42137005-42137085 7.05e-01 80 chr19:38908621-38908701 4.09e-01 80 chr3:49727048-49727128 2.42e-01 80 chr22:36851179-36851259 6.28e-01 80 chr8:8751409-8751489 2.19e-01 80 chr16:46667248-46667328 3.03e-01 80 chr4:1748109-1748189 1.86e-01 80 chr16:85309295-85309375 2.04e-01 80 chr19:48794547-48794627 2.90e-01 80 chr13:47370762-47370842 2.52e-01 80 chr9:90449760-90449840 3.75e-05 1_[+5(6.13e-06)]_21_[+3(6.45e-05)]_\ 3_[+2(8.86e-05)]_31 chr6:155963922-155964002 4.25e-02 72_[+2(5.20e-05)] chr2:111880581-111880661 5.89e-01 80 chr6:106348579-106348659 3.41e-01 80 chr1:11740881-11740961 4.06e-01 80 chr9:136285587-136285667 7.77e-02 80 chr20:50163466-50163546 1.41e-01 80 chr13:27936508-27936588 6.71e-02 80 chr5:95298030-95298110 1.24e-01 56_[+1(7.32e-05)]_16 chr14:101696610-10169669 3.63e-03 59_[+3(6.45e-05)]_3_[+2(8.86e-05)]_\ 2 chr2:27806154-27806234 5.06e-01 80 chr22:30234259-30234339 4.85e-01 80 chr16:88590140-88590220 1.59e-01 54_[+3(9.87e-05)]_18 chr16:47813855-47813935 9.17e-02 80 chr2:43134238-43134318 7.23e-01 80 chr19:50441138-50441218 3.00e-01 80 chr4:6332956-6333036 3.06e-02 44_[+2(5.20e-05)]_28 chr21:44723906-44723986 3.55e-03 80 chr5:38798121-38798201 3.46e-05 13_[+5(6.13e-06)]_21_[+3(9.87e-05)]_\ 3_[+2(8.86e-05)]_19 chr9:102668730-102668810 3.70e-01 80 chr6:27799356-27799436 2.78e-02 80 chr11:98603841-98603921 3.47e-02 80 chr12:15841327-15841407 4.59e-04 27_[+1(5.09e-05)]_45 chr1:10062964-10063044 1.12e-02 54_[+1(1.45e-05)]_18 chr9:130159489-130159569 2.78e-01 80 chr6:33133713-33133793 4.80e-02 80 chr19:56915253-56915333 5.28e-02 80 chr22:39615446-39615526 8.31e-03 6_[+1(7.32e-05)]_40_[+1(1.45e-05)]_\ 18 chr13:96336299-96336379 1.33e-01 57_[+1(7.32e-05)]_15 chr10:99257589-99257669 2.99e-01 80 chr4:185570909-185570989 6.57e-01 80 chr17:38059851-38059931 2.32e-01 80 chrX:150067418-150067498 2.85e-02 80 chr6:126656548-126656628 1.31e-01 80 chr5:148064594-148064674 4.49e-02 80 chr16:838694-838774 4.44e-01 80 -------------------------------------------------------------------------------- ******************************************************************************** ******************************************************************************** Stopped because requested number of motifs (5) found. ******************************************************************************** CPU: c22n07.farnam.hpc.yale.internal ********************************************************************************