******************************************************************************** MEME - Motif discovery tool ******************************************************************************** MEME version 5.3.3 (Release date: Sun Feb 7 15:39:52 2021 -0800) For further information on how to interpret these results please access https://meme-suite.org/meme. To get a copy of the MEME Suite software please access https://meme-suite.org. ******************************************************************************** ******************************************************************************** REFERENCE ******************************************************************************** If you use this program in your research, please cite: Timothy L. Bailey and Charles Elkan, "Fitting a mixture model by expectation maximization to discover motifs in biopolymers", Proceedings of the Second International Conference on Intelligent Systems for Molecular Biology, pp. 28-36, AAAI Press, Menlo Park, California, 1994. ******************************************************************************** ******************************************************************************** TRAINING SET ******************************************************************************** PRIMARY SEQUENCES= ../result/final_prediction/K562/fasta/RankLinear0.6_40/HES1.fasta CONTROL SEQUENCES= --none-- ALPHABET= ACGT Sequence name Weight Length Sequence name Weight Length ------------- ------ ------ ------------- ------ ------ chr4:142063796-142063876 1.0000 80 chr8:97222446-97222526 1.0000 80 chr2:9105867-9105947 1.0000 80 chr2:39444149-39444229 1.0000 80 chr4:114558204-114558284 1.0000 80 chr9:116058676-116058756 1.0000 80 chr16:28135654-28135734 1.0000 80 chr17:65330519-65330599 1.0000 80 chr16:28006869-28006949 1.0000 80 chr18:9082088-9082168 1.0000 80 chr1:53581725-53581805 1.0000 80 chr11:62269948-62270028 1.0000 80 chr1:12015436-12015516 1.0000 80 chr5:154120680-154120760 1.0000 80 chr10:35736749-35736829 1.0000 80 chr2:85934587-85934667 1.0000 80 chr18:499633-499713 1.0000 80 chr2:135356100-135356180 1.0000 80 chr1:222885472-222885552 1.0000 80 chr6:170404946-170405026 1.0000 80 chr4:1633939-1634019 1.0000 80 chr6:41735027-41735107 1.0000 80 chr19:5894559-5894639 1.0000 80 chr4:26320916-26320996 1.0000 80 chr1:109159831-109159911 1.0000 80 chr1:61557372-61557452 1.0000 80 chr14:100288218-10028829 1.0000 80 chr10:97278288-97278368 1.0000 80 chr3:20145945-20146025 1.0000 80 chr3:98270672-98270752 1.0000 80 chr17:76623391-76623471 1.0000 80 chr1:212612429-212612509 1.0000 80 chrX:40709663-40709743 1.0000 80 chr16:19405161-19405241 1.0000 80 chr17:80101381-80101461 1.0000 80 chr7:105284037-105284117 1.0000 80 chr21:43203826-43203906 1.0000 80 chr9:138876744-138876824 1.0000 80 chr3:107725098-107725178 1.0000 80 chr6:37170776-37170856 1.0000 80 chr5:73622914-73622994 1.0000 80 chr3:195634840-195634920 1.0000 80 chr10:73103201-73103281 1.0000 80 chr16:86959178-86959258 1.0000 80 chr7:44331157-44331237 1.0000 80 chr21:47714555-47714635 1.0000 80 chr6:158826580-158826660 1.0000 80 chr5:112267345-112267425 1.0000 80 chr8:3086489-3086569 1.0000 80 chr17:42767771-42767851 1.0000 80 chr3:155546461-155546541 1.0000 80 chr11:12136272-12136352 1.0000 80 chr8:142046295-142046375 1.0000 80 chr3:45615749-45615829 1.0000 80 chr21:47451500-47451580 1.0000 80 chr14:22966934-22967014 1.0000 80 chrX:109965536-109965616 1.0000 80 chr11:1804325-1804405 1.0000 80 chr6:150400060-150400140 1.0000 80 chr18:46131844-46131924 1.0000 80 chr19:41857462-41857542 1.0000 80 chr1:59492293-59492373 1.0000 80 chr7:39775690-39775770 1.0000 80 chr2:24404892-24404972 1.0000 80 chr10:81293625-81293705 1.0000 80 chr1:214176733-214176813 1.0000 80 chr5:107955700-107955780 1.0000 80 chr22:48486000-48486080 1.0000 80 chr3:170731724-170731804 1.0000 80 chr2:48211340-48211420 1.0000 80 chr1:16521757-16521837 1.0000 80 chr9:126817193-126817273 1.0000 80 chr21:43348983-43349063 1.0000 80 chr17:64538051-64538131 1.0000 80 chr1:35896861-35896941 1.0000 80 chr3:128292890-128292970 1.0000 80 chr14:23197617-23197697 1.0000 80 chr1:209848511-209848591 1.0000 80 chr9:123446761-123446841 1.0000 80 chr5:136015032-136015112 1.0000 80 chr14:104625328-10462540 1.0000 80 chr21:44782944-44783024 1.0000 80 chr14:23025411-23025491 1.0000 80 chr2:111920542-111920622 1.0000 80 chr21:46529817-46529897 1.0000 80 chr2:75089581-75089661 1.0000 80 chr16:69459204-69459284 1.0000 80 chr1:156896109-156896189 1.0000 80 chr3:171824904-171824984 1.0000 80 chr10:11866928-11867008 1.0000 80 chr20:47654645-47654725 1.0000 80 chr11:2959244-2959324 1.0000 80 chr19:13162530-13162610 1.0000 80 chr11:118187490-11818757 1.0000 80 chr7:98520504-98520584 1.0000 80 chr17:76136252-76136332 1.0000 80 chr7:4456185-4456265 1.0000 80 chr6:170595922-170596002 1.0000 80 chr14:101909019-10190909 1.0000 80 chr1:181120803-181120883 1.0000 80 chr10:121545758-12154583 1.0000 80 chr6:90031439-90031519 1.0000 80 chr8:12400653-12400733 1.0000 80 chr4:6927380-6927460 1.0000 80 chr2:46361843-46361923 1.0000 80 chr6:151183040-151183120 1.0000 80 chr20:42579023-42579103 1.0000 80 chr15:82333350-82333430 1.0000 80 chr15:66615856-66615936 1.0000 80 chr19:54714758-54714838 1.0000 80 chr12:4430043-4430123 1.0000 80 chrX:135213288-135213368 1.0000 80 chr1:16478023-16478103 1.0000 80 chr16:11706375-11706455 1.0000 80 chr1:204370147-204370227 1.0000 80 chr8:48911638-48911718 1.0000 80 chr4:113437681-113437761 1.0000 80 chr3:142569292-142569372 1.0000 80 chr3:58457212-58457292 1.0000 80 chr1:110981672-110981752 1.0000 80 chr11:76092220-76092300 1.0000 80 chr6:101396775-101396855 1.0000 80 chr21:40467210-40467290 1.0000 80 chr19:18854224-18854304 1.0000 80 chr15:89560855-89560935 1.0000 80 chr17:63225262-63225342 1.0000 80 chr17:72711380-72711460 1.0000 80 chr1:101757242-101757322 1.0000 80 chr6:43359347-43359427 1.0000 80 chr5:175866132-175866212 1.0000 80 chr8:124526623-124526703 1.0000 80 chr5:131439429-131439509 1.0000 80 chr17:4110432-4110512 1.0000 80 chrX:18372952-18373032 1.0000 80 chr17:32269576-32269656 1.0000 80 chrX:48794439-48794519 1.0000 80 chr8:116480005-116480085 1.0000 80 chr5:133023042-133023122 1.0000 80 chr1:47845362-47845442 1.0000 80 chr7:135335782-135335862 1.0000 80 chr16:374574-374654 1.0000 80 chr8:102049443-102049523 1.0000 80 chr6:159920179-159920259 1.0000 80 chr4:4463781-4463861 1.0000 80 chr18:12337069-12337149 1.0000 80 chr10:26511661-26511741 1.0000 80 chr6:36793341-36793421 1.0000 80 chr12:132111994-13211207 1.0000 80 chr6:130088430-130088510 1.0000 80 chr21:45118567-45118647 1.0000 80 chr2:38779500-38779580 1.0000 80 chr20:46153259-46153339 1.0000 80 chrX:129259372-129259452 1.0000 80 chr2:17775204-17775284 1.0000 80 chr11:10764471-10764551 1.0000 80 chr9:77642631-77642711 1.0000 80 chr9:130150787-130150867 1.0000 80 chr3:194041745-194041825 1.0000 80 chr3:33109111-33109191 1.0000 80 chr9:136734916-136734996 1.0000 80 chr7:86741370-86741450 1.0000 80 chr19:17828334-17828414 1.0000 80 chr17:57635556-57635636 1.0000 80 chr2:170972521-170972601 1.0000 80 chr7:108056800-108056880 1.0000 80 chr22:39632614-39632694 1.0000 80 chr13:22562082-22562162 1.0000 80 chr11:33907046-33907126 1.0000 80 chr17:72159816-72159896 1.0000 80 chr9:110582193-110582273 1.0000 80 chr22:19592450-19592530 1.0000 80 chr11:46358486-46358566 1.0000 80 chr1:184899951-184900031 1.0000 80 chr17:549352-549432 1.0000 80 chr12:27996755-27996835 1.0000 80 chr6:107860743-107860823 1.0000 80 chr3:37824244-37824324 1.0000 80 chr8:10513965-10514045 1.0000 80 chr1:63869215-63869295 1.0000 80 chr7:73037433-73037513 1.0000 80 chr16:19407081-19407161 1.0000 80 chr1:165362413-165362493 1.0000 80 chr2:109830635-109830715 1.0000 80 chr6:341426-341506 1.0000 80 chr12:13589984-13590064 1.0000 80 chr1:3111284-3111364 1.0000 80 chr19:2974636-2974716 1.0000 80 chr4:170679182-170679262 1.0000 80 chr16:55469436-55469516 1.0000 80 chr17:35405044-35405124 1.0000 80 chr8:17388570-17388650 1.0000 80 chrX:129890421-129890501 1.0000 80 chr7:1781851-1781931 1.0000 80 chr9:88358309-88358389 1.0000 80 chr1:75889384-75889464 1.0000 80 chr10:49514398-49514478 1.0000 80 chr2:113627083-113627163 1.0000 80 chr3:193852814-193852894 1.0000 80 chr1:229284004-229284084 1.0000 80 chr2:159594995-159595075 1.0000 80 chr18:9966177-9966257 1.0000 80 chr16:1001900-1001980 1.0000 80 chr3:133175006-133175086 1.0000 80 chr17:42061333-42061413 1.0000 80 chr21:45158514-45158594 1.0000 80 chr12:123717928-12371800 1.0000 80 chr19:18794557-18794637 1.0000 80 chr14:103987575-10398765 1.0000 80 chr8:70815904-70815984 1.0000 80 chr3:148869809-148869889 1.0000 80 chr2:9854834-9854914 1.0000 80 chr8:80731010-80731090 1.0000 80 chr6:149461268-149461348 1.0000 80 chr19:7866260-7866340 1.0000 80 chr17:17109799-17109879 1.0000 80 chr7:22341490-22341570 1.0000 80 chr1:116963138-116963218 1.0000 80 chr19:55471341-55471421 1.0000 80 chr5:123985551-123985631 1.0000 80 chr18:77720301-77720381 1.0000 80 chr1:9470998-9471078 1.0000 80 chr17:35242610-35242690 1.0000 80 chr8:56852607-56852687 1.0000 80 chr3:193853799-193853879 1.0000 80 chr17:33571593-33571673 1.0000 80 chr22:19709872-19709952 1.0000 80 chr11:108094323-10809440 1.0000 80 chr11:2960016-2960096 1.0000 80 chr11:74637491-74637571 1.0000 80 chr21:47712963-47713043 1.0000 80 chr1:110268294-110268374 1.0000 80 chr7:6261068-6261148 1.0000 80 chr14:71353541-71353621 1.0000 80 chr16:50875125-50875205 1.0000 80 chr1:225566765-225566845 1.0000 80 chr5:95997547-95997627 1.0000 80 chr20:20213815-20213895 1.0000 80 chr9:71786059-71786139 1.0000 80 chr13:42570225-42570305 1.0000 80 chr3:48701107-48701187 1.0000 80 chr6:25974284-25974364 1.0000 80 chr10:105264412-10526449 1.0000 80 chr8:96143618-96143698 1.0000 80 chr10:105264213-10526429 1.0000 80 chr7:128063903-128063983 1.0000 80 chr6:30956373-30956453 1.0000 80 chr1:59280981-59281061 1.0000 80 chr2:3606236-3606316 1.0000 80 chr16:90235246-90235326 1.0000 80 chr1:222883259-222883339 1.0000 80 ******************************************************************************** ******************************************************************************** COMMAND LINE SUMMARY ******************************************************************************** This information can also be useful in the event you wish to report a problem with the MEME software. command: meme -oc ../result/final_prediction/K562/inference_raw/MEME/RankLinear0.6_40_HES1/ -dna -nmotifs 5 -w 8 -maxsize 250000 -nostatus ../result/final_prediction/K562/fasta/RankLinear0.6_40/HES1.fasta model: mod= zoops nmotifs= 5 evt= inf objective function: em= E-value of product of p-values starts= E-value of product of p-values strands: + width: minw= 8 maxw= 8 nsites: minsites= 2 maxsites= 250 wnsites= 0.8 theta: spmap= uni spfuzz= 0.5 em: prior= dirichlet b= 0.01 maxiter= 50 distance= 1e-05 trim: wg= 11 ws= 1 endgaps= yes data: n= 20000 N= 250 sample: seed= 0 hsfrac= 0 searchsize= 20000 norand= no csites= 1000 Letter frequencies in dataset: A 0.245 C 0.262 G 0.246 T 0.247 Background letter frequencies (from file dataset with add-one prior applied): A 0.245 C 0.262 G 0.246 T 0.248 Background model order: 0 ******************************************************************************** ******************************************************************************** MOTIF WGATAASA MEME-1 width = 8 sites = 65 llr = 507 E-value = 6.4e-020 ******************************************************************************** -------------------------------------------------------------------------------- Motif WGATAASA MEME-1 Description -------------------------------------------------------------------------------- Simplified A 6:a:a825 pos.-specific C ::::::32 probability G :a:::252 matrix T 4::a:::1 bits 2.0 **** 1.8 **** 1.6 **** 1.4 ***** Relative 1.2 ***** Entropy 1.0 ****** (11.3 bits) 0.8 ****** 0.6 ******* 0.4 ******* 0.2 ******** 0.0 -------- Multilevel AGATAAGA consensus T CG sequence A -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif WGATAASA MEME-1 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr12:123717928-12371800 25 1.32e-05 AGCCTCTGGT AGATAAGA GAAACCGCGA chr16:55469436-55469516 42 1.32e-05 TGCCTACAGG AGATAAGA GGCTGGTGTG chr2:109830635-109830715 67 1.32e-05 aaaccacaag agataaga tcaccc chr21:40467210-40467290 1 1.32e-05 . AGATAAGA CAGTAATTTC chr1:35896861-35896941 1 1.32e-05 . AGATAAGA TAGGAATAAA chr14:22966934-22967014 27 1.32e-05 GGAAAGGCAG AGATAAGA AGCAAAGCTT chr3:155546461-155546541 47 1.32e-05 ccttgtgagt agataaga ccacaggcgt chr16:28135654-28135734 33 1.32e-05 ccAACTGAAC AGATAAGA TATATCTATA chrX:129259372-129259452 37 2.67e-05 AGGAATTCCC TGATAAGA TGGGAAAGAG chr10:26511661-26511741 12 2.67e-05 TGCCTGAGGC TGATAAGA GAGCACTCCA chr1:204370147-204370227 21 2.67e-05 TGTCTCTCTC TGATAAGA TTAAGGCGTC chr11:62269948-62270028 20 2.67e-05 GATCGGTTAG TGATAAGA TGGCttatca chr13:42570225-42570305 13 4.08e-05 CACCCAGCAG AGATAACA GCCAAATATG chr8:17388570-17388650 24 4.08e-05 CAGGGCTGGG AGATAACA GGGCTGGTTT chr7:86741370-86741450 61 4.08e-05 AACACTGTGA AGATAACA CGGACAATTA chr6:43359347-43359427 40 4.08e-05 atgattcagg agataaca aaagtgacac chr5:136015032-136015112 70 4.08e-05 ACGCCTGCAG AGATAACA ATT chr6:30956373-30956453 51 5.41e-05 GACTTGGGAG AGATAAGG AGGGAGGGCG chr16:50875125-50875205 54 5.41e-05 cggggcgcgc AGATAAGG TCTGGGGGCG chr6:151183040-151183120 29 5.41e-05 tttgcggttg agataagg ggaagttttc chr2:75089581-75089661 11 5.41e-05 TGTGCTGGGG AGATAAGG CCCATGTAGA chr17:42767771-42767851 69 5.41e-05 cacattttaa agataagg agac chr20:46153259-46153339 23 6.73e-05 atgccagttt agataaaa tgacttgggc chr14:23197617-23197697 48 6.73e-05 atttcccaac agataaaa atgcggctgg chr17:33571593-33571673 26 9.57e-05 CAATTCAGTG TGATAACA TCCTGTGTCA chr9:110582193-110582273 21 9.57e-05 AGGCCAAGCC TGATAACA ATCAGTCAAT chr7:98520504-98520584 71 9.57e-05 AAGCTGGTAC AGATAAGC GT chr3:128292890-128292970 72 9.57e-05 TGGTTTCCAC AGATAAGC A chr17:64538051-64538131 32 9.57e-05 TATGTAAGGC TGATAACA AGCCACCACG chr3:45615749-45615829 19 9.57e-05 actggccttg agataagc aatactgaaa chr12:13589984-13590064 23 1.09e-04 CCTTCCCCCC TGATAAGG CACAACCACA chr17:549352-549432 33 1.09e-04 GGCCTCTGCC TGATAAGG GTCTTATCTT chr8:48911638-48911718 47 1.09e-04 ccatggccct tgataagg gcttagaaat chr19:54714758-54714838 43 1.09e-04 GGCAATGTGC TGATAAGG ATTCTAAGTG chr10:121545758-12154583 26 1.09e-04 TTCAGAGTTG TGATAAGG ACCTAACCAC chr8:3086489-3086569 45 1.09e-04 CTGAGAAGGC TGATAAGG ACAGCTATCC chr17:76623391-76623471 15 1.09e-04 AGCCATGAAA TGATAAGG ACACCGCAGC chr7:22341490-22341570 14 1.51e-04 AGAACCTTTG TGATAAGC TCCCAGGTAT chr8:80731010-80731090 32 1.51e-04 GAAGATTATG TGATAAGC AGACCATATC chr8:70815904-70815984 37 1.64e-04 tttttttttg agatagga tcttgctttg chr10:97278288-97278368 9 1.64e-04 aagAGAAG AGATAGGA TGCTGTTGAG chr11:108094323-10809440 27 2.06e-04 TGTCTTGTGA AGATAAGT GAGATAATCT chr11:10764471-10764551 48 2.06e-04 ACTCTGGCGT AGATAAGT CAGTATGACC chr2:39444149-39444229 44 2.06e-04 TGCAAAGAGA AGATAACC ATCAAAGAGA chr17:57635556-57635636 54 2.48e-04 tccaaccata agataaac ccctccccga chr4:4463781-4463861 47 2.90e-04 attttaccaa tgataaag ctgatatgac chr2:48211340-48211420 44 2.90e-04 TGAGGGCTGC TGATAACC ACAGTATTTC chr10:35736749-35736829 30 2.90e-04 ACAGATAGTT TGATAAAG GCATAACAGG chr1:9470998-9471078 66 3.04e-04 TCTGGCCTCC AGATAGCA CAGTCCC chr1:110981672-110981752 18 3.04e-04 ttactgtgag agatagca gcatgatttg chr14:23025411-23025491 37 3.04e-04 ACTGAGTTAG AGATAGCA TCGCCCCAGG chr3:170731724-170731804 9 3.04e-04 GGGCTTTG AGATAGCA AGCAGTACCA chr8:12400653-12400733 68 3.32e-04 gcacagcaat agataact aataT chr6:36793341-36793421 8 3.46e-04 AACCATC TGATAAAC CTCCCAGCCC chr6:101396775-101396855 15 3.46e-04 cccttcctgt tgataaac tacctcagtt chr2:135356100-135356180 69 3.46e-04 tgacacaaac tgataaac aaga chr1:109159831-109159911 23 3.60e-04 actctgagtg agatagaa aagctattgg chr17:35242610-35242690 9 4.02e-04 aataataa tgatagca accctgggcc chr2:113627083-113627163 25 4.02e-04 CAACATCCGC TGATAGCA TCAGTAATAA chr8:124526623-124526703 56 4.02e-04 TGACGGGGAG AGATAAAT GGCAGGCAGG chr7:6261068-6261148 18 4.30e-04 ggagggagcc tgataact ttgtggtgat chr7:4456185-4456265 31 4.57e-04 GCAAAGTgaa tgatagaa tctcaaagct chr5:73622914-73622994 39 4.85e-04 GAAGTCGCAC TGATAAAT CCTGCCCACA chr11:46358486-46358566 63 5.27e-04 cgaggctggg agatagag tgagatcctg chr11:33907046-33907126 58 5.27e-04 GTTAGCCCGG AGATAGCC TTAGGCAGTA -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif WGATAASA MEME-1 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr12:123717928-12371800 1.3e-05 24_[+1]_48 chr16:55469436-55469516 1.3e-05 41_[+1]_31 chr2:109830635-109830715 1.3e-05 66_[+1]_6 chr21:40467210-40467290 1.3e-05 [+1]_72 chr1:35896861-35896941 1.3e-05 [+1]_72 chr14:22966934-22967014 1.3e-05 26_[+1]_46 chr3:155546461-155546541 1.3e-05 46_[+1]_26 chr16:28135654-28135734 1.3e-05 32_[+1]_40 chrX:129259372-129259452 2.7e-05 36_[+1]_36 chr10:26511661-26511741 2.7e-05 11_[+1]_61 chr1:204370147-204370227 2.7e-05 20_[+1]_52 chr11:62269948-62270028 2.7e-05 19_[+1]_53 chr13:42570225-42570305 4.1e-05 12_[+1]_60 chr8:17388570-17388650 4.1e-05 23_[+1]_49 chr7:86741370-86741450 4.1e-05 60_[+1]_12 chr6:43359347-43359427 4.1e-05 39_[+1]_33 chr5:136015032-136015112 4.1e-05 69_[+1]_3 chr6:30956373-30956453 5.4e-05 50_[+1]_22 chr16:50875125-50875205 5.4e-05 53_[+1]_19 chr6:151183040-151183120 5.4e-05 28_[+1]_44 chr2:75089581-75089661 5.4e-05 10_[+1]_62 chr17:42767771-42767851 5.4e-05 68_[+1]_4 chr20:46153259-46153339 6.7e-05 22_[+1]_50 chr14:23197617-23197697 6.7e-05 47_[+1]_25 chr17:33571593-33571673 9.6e-05 25_[+1]_47 chr9:110582193-110582273 9.6e-05 20_[+1]_52 chr7:98520504-98520584 9.6e-05 70_[+1]_2 chr3:128292890-128292970 9.6e-05 71_[+1]_1 chr17:64538051-64538131 9.6e-05 31_[+1]_41 chr3:45615749-45615829 9.6e-05 18_[+1]_54 chr12:13589984-13590064 0.00011 22_[+1]_50 chr17:549352-549432 0.00011 32_[+1]_40 chr8:48911638-48911718 0.00011 46_[+1]_26 chr19:54714758-54714838 0.00011 42_[+1]_30 chr10:121545758-12154583 0.00011 25_[+1]_47 chr8:3086489-3086569 0.00011 44_[+1]_28 chr17:76623391-76623471 0.00011 14_[+1]_58 chr7:22341490-22341570 0.00015 13_[+1]_59 chr8:80731010-80731090 0.00015 31_[+1]_41 chr8:70815904-70815984 0.00016 36_[+1]_36 chr10:97278288-97278368 0.00016 8_[+1]_64 chr11:108094323-10809440 0.00021 26_[+1]_46 chr11:10764471-10764551 0.00021 47_[+1]_25 chr2:39444149-39444229 0.00021 43_[+1]_29 chr17:57635556-57635636 0.00025 53_[+1]_19 chr4:4463781-4463861 0.00029 46_[+1]_26 chr2:48211340-48211420 0.00029 43_[+1]_29 chr10:35736749-35736829 0.00029 29_[+1]_43 chr1:9470998-9471078 0.0003 65_[+1]_7 chr1:110981672-110981752 0.0003 17_[+1]_55 chr14:23025411-23025491 0.0003 36_[+1]_36 chr3:170731724-170731804 0.0003 8_[+1]_64 chr8:12400653-12400733 0.00033 67_[+1]_5 chr6:36793341-36793421 0.00035 7_[+1]_65 chr6:101396775-101396855 0.00035 14_[+1]_58 chr2:135356100-135356180 0.00035 68_[+1]_4 chr1:109159831-109159911 0.00036 22_[+1]_50 chr17:35242610-35242690 0.0004 8_[+1]_64 chr2:113627083-113627163 0.0004 24_[+1]_48 chr8:124526623-124526703 0.0004 55_[+1]_17 chr7:6261068-6261148 0.00043 17_[+1]_55 chr7:4456185-4456265 0.00046 30_[+1]_42 chr5:73622914-73622994 0.00049 38_[+1]_34 chr11:46358486-46358566 0.00053 62_[+1]_10 chr11:33907046-33907126 0.00053 57_[+1]_15 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif WGATAASA MEME-1 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF WGATAASA width=8 seqs=65 chr12:123717928-12371800 ( 25) AGATAAGA 1 chr16:55469436-55469516 ( 42) AGATAAGA 1 chr2:109830635-109830715 ( 67) AGATAAGA 1 chr21:40467210-40467290 ( 1) AGATAAGA 1 chr1:35896861-35896941 ( 1) AGATAAGA 1 chr14:22966934-22967014 ( 27) AGATAAGA 1 chr3:155546461-155546541 ( 47) AGATAAGA 1 chr16:28135654-28135734 ( 33) AGATAAGA 1 chrX:129259372-129259452 ( 37) TGATAAGA 1 chr10:26511661-26511741 ( 12) TGATAAGA 1 chr1:204370147-204370227 ( 21) TGATAAGA 1 chr11:62269948-62270028 ( 20) TGATAAGA 1 chr13:42570225-42570305 ( 13) AGATAACA 1 chr8:17388570-17388650 ( 24) AGATAACA 1 chr7:86741370-86741450 ( 61) AGATAACA 1 chr6:43359347-43359427 ( 40) AGATAACA 1 chr5:136015032-136015112 ( 70) AGATAACA 1 chr6:30956373-30956453 ( 51) AGATAAGG 1 chr16:50875125-50875205 ( 54) AGATAAGG 1 chr6:151183040-151183120 ( 29) AGATAAGG 1 chr2:75089581-75089661 ( 11) AGATAAGG 1 chr17:42767771-42767851 ( 69) AGATAAGG 1 chr20:46153259-46153339 ( 23) AGATAAAA 1 chr14:23197617-23197697 ( 48) AGATAAAA 1 chr17:33571593-33571673 ( 26) TGATAACA 1 chr9:110582193-110582273 ( 21) TGATAACA 1 chr7:98520504-98520584 ( 71) AGATAAGC 1 chr3:128292890-128292970 ( 72) AGATAAGC 1 chr17:64538051-64538131 ( 32) TGATAACA 1 chr3:45615749-45615829 ( 19) AGATAAGC 1 chr12:13589984-13590064 ( 23) TGATAAGG 1 chr17:549352-549432 ( 33) TGATAAGG 1 chr8:48911638-48911718 ( 47) TGATAAGG 1 chr19:54714758-54714838 ( 43) TGATAAGG 1 chr10:121545758-12154583 ( 26) TGATAAGG 1 chr8:3086489-3086569 ( 45) TGATAAGG 1 chr17:76623391-76623471 ( 15) TGATAAGG 1 chr7:22341490-22341570 ( 14) TGATAAGC 1 chr8:80731010-80731090 ( 32) TGATAAGC 1 chr8:70815904-70815984 ( 37) AGATAGGA 1 chr10:97278288-97278368 ( 9) AGATAGGA 1 chr11:108094323-10809440 ( 27) AGATAAGT 1 chr11:10764471-10764551 ( 48) AGATAAGT 1 chr2:39444149-39444229 ( 44) AGATAACC 1 chr17:57635556-57635636 ( 54) AGATAAAC 1 chr4:4463781-4463861 ( 47) TGATAAAG 1 chr2:48211340-48211420 ( 44) TGATAACC 1 chr10:35736749-35736829 ( 30) TGATAAAG 1 chr1:9470998-9471078 ( 66) AGATAGCA 1 chr1:110981672-110981752 ( 18) AGATAGCA 1 chr14:23025411-23025491 ( 37) AGATAGCA 1 chr3:170731724-170731804 ( 9) AGATAGCA 1 chr8:12400653-12400733 ( 68) AGATAACT 1 chr6:36793341-36793421 ( 8) TGATAAAC 1 chr6:101396775-101396855 ( 15) TGATAAAC 1 chr2:135356100-135356180 ( 69) TGATAAAC 1 chr1:109159831-109159911 ( 23) AGATAGAA 1 chr17:35242610-35242690 ( 9) TGATAGCA 1 chr2:113627083-113627163 ( 25) TGATAGCA 1 chr8:124526623-124526703 ( 56) AGATAAAT 1 chr7:6261068-6261148 ( 18) TGATAACT 1 chr7:4456185-4456265 ( 31) TGATAGAA 1 chr5:73622914-73622994 ( 39) TGATAAAT 1 chr11:46358486-46358566 ( 63) AGATAGAG 1 chr11:33907046-33907126 ( 58) AGATAGCC 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif WGATAASA MEME-1 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 9.87609 E= 6.4e-020 126 -1267 -1267 75 -1267 -1267 202 -1267 203 -1267 -1267 -1267 -1267 -1267 -1267 201 203 -1267 -1267 -1267 174 -1267 -41 -1267 -29 16 105 -1267 101 -51 -9 -142 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif WGATAASA MEME-1 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 65 E= 6.4e-020 0.584615 0.000000 0.000000 0.415385 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 1.000000 0.000000 0.000000 0.000000 0.815385 0.000000 0.184615 0.000000 0.200000 0.292308 0.507692 0.000000 0.492308 0.184615 0.230769 0.092308 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif WGATAASA MEME-1 regular expression -------------------------------------------------------------------------------- [AT]GATAA[GCA][AG] -------------------------------------------------------------------------------- Time 5.62 secs. ******************************************************************************** ******************************************************************************** MOTIF WAACCACA MEME-2 width = 8 sites = 35 llr = 314 E-value = 8.8e-013 ******************************************************************************** -------------------------------------------------------------------------------- Motif WAACCACA MEME-2 Description -------------------------------------------------------------------------------- Simplified A 689::9:a pos.-specific C 1::aa:a: probability G :21::1:: matrix T 3::::::: bits 2.0 ** ** 1.8 ** ** 1.6 ** ** 1.4 ****** Relative 1.2 ******* Entropy 1.0 ******* (12.9 bits) 0.8 ******** 0.6 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel AAACCACA consensus TG sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif WAACCACA MEME-2 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr16:1001900-1001980 39 1.59e-05 CATCGGGGGC AAACCACA AACAGCCACA chr19:2974636-2974716 22 1.59e-05 GCTGCAATCC AAACCACA TTCGGAAAAA chr2:109830635-109830715 57 1.59e-05 tttatgggta aaaccaca agagataaga chr7:108056800-108056880 47 1.59e-05 GGAAAAGATT AAACCACA GGCGTGTGGC chr5:131439429-131439509 68 1.59e-05 CCTGTTACAG AAACCACA GGCCT chr17:72711380-72711460 72 1.59e-05 TTTGCACAGA AAACCACA G chr3:142569292-142569372 35 1.59e-05 tgaagaggtc aaaccaca atagagactg chr3:20145945-20146025 36 1.59e-05 GGAATTAAAA AAACCACA TACCACCACA chr10:97278288-97278368 62 1.59e-05 ACCTATCATG AAACCACA TCTGCCTGGC chr10:35736749-35736829 15 1.59e-05 ACGTGGCTGT AAACCACA GATAGTTTGA chr16:28006869-28006949 49 1.59e-05 TTTCCCTGCA AAACCACA AAGATAATTG chr6:107860743-107860823 43 3.19e-05 CTTTTAACAT TAACCACA GTGTCAGATT chr6:130088430-130088510 26 3.19e-05 TCTTCACGGC TAACCACA ATCCTGTCAT chr17:4110432-4110512 24 3.19e-05 ccgacccgtc taaccaca gagggcccga chr19:54714758-54714838 2 3.19e-05 A TAACCACA CTCCAGCGTG chr10:121545758-12154583 37 3.19e-05 GATAAGGACC TAACCACA TACCACACAG chr9:126817193-126817273 20 3.19e-05 ACTAAACCAA TAACCACA GAATGGTTCT chr10:105264213-10526429 16 4.79e-05 ttggagtgaa agaccaca gaggtaaagt chr12:132111994-13211207 15 4.79e-05 CATCCGCCCG AGACCACA GCCACTCCCC chr16:374574-374654 32 4.79e-05 TGTTATCACA AGACCACA CGCCGCACGT chr1:59280981-59281061 61 6.38e-05 TGTGTAAATA AAGCCACA GACTTCCGCC chr6:43359347-43359427 7 6.38e-05 ccacag aagccaca gacaaaccgg chr8:12400653-12400733 30 6.38e-05 gtgctgtctc aagccaca aagtttgcag chr21:46529817-46529897 37 6.38e-05 CATTAGTGGA AAGCCACA AGTAGCGTGG chr8:10513965-10514045 66 9.59e-05 agacaggagt aaaccgca actgtcc chr22:39632614-39632694 24 9.59e-05 TCCTCCAGGG AAACCGCA GGTCCCACAA chr17:57635556-57635636 12 9.59e-05 gcatgaccat aaaccgca aatgacatct chr21:40467210-40467290 54 9.59e-05 CCACACTCCA TGACCACA CAGCCTACGA chr17:64538051-64538131 7 9.59e-05 TTTGGC TGACCACA TTTGTTCTAT chr3:170731724-170731804 35 9.59e-05 CAGCAGCCAG AAACCGCA TAACAAATAC chr5:112267345-112267425 32 9.59e-05 AATCATGCTG TGACCACA CTGGTTGACT chr4:114558204-114558284 46 9.59e-05 taccataatc tgaccaca atctgaccac chr2:9105867-9105947 38 1.12e-04 tgatagccac tagccaca cgCCCATCAA chr12:13589984-13590064 33 1.29e-04 TGATAAGGCA CAACCACA TCCATGGCTT chr12:4430043-4430123 31 1.29e-04 TCAATCGCAA CAACCACA AATCAGTGCG -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif WAACCACA MEME-2 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr16:1001900-1001980 1.6e-05 38_[+2]_34 chr19:2974636-2974716 1.6e-05 21_[+2]_51 chr2:109830635-109830715 1.6e-05 56_[+2]_16 chr7:108056800-108056880 1.6e-05 46_[+2]_26 chr5:131439429-131439509 1.6e-05 67_[+2]_5 chr17:72711380-72711460 1.6e-05 71_[+2]_1 chr3:142569292-142569372 1.6e-05 34_[+2]_38 chr3:20145945-20146025 1.6e-05 35_[+2]_37 chr10:97278288-97278368 1.6e-05 61_[+2]_11 chr10:35736749-35736829 1.6e-05 14_[+2]_58 chr16:28006869-28006949 1.6e-05 48_[+2]_24 chr6:107860743-107860823 3.2e-05 42_[+2]_30 chr6:130088430-130088510 3.2e-05 25_[+2]_47 chr17:4110432-4110512 3.2e-05 23_[+2]_49 chr19:54714758-54714838 3.2e-05 1_[+2]_71 chr10:121545758-12154583 3.2e-05 36_[+2]_36 chr9:126817193-126817273 3.2e-05 19_[+2]_53 chr10:105264213-10526429 4.8e-05 15_[+2]_57 chr12:132111994-13211207 4.8e-05 14_[+2]_58 chr16:374574-374654 4.8e-05 31_[+2]_41 chr1:59280981-59281061 6.4e-05 60_[+2]_12 chr6:43359347-43359427 6.4e-05 6_[+2]_66 chr8:12400653-12400733 6.4e-05 29_[+2]_43 chr21:46529817-46529897 6.4e-05 36_[+2]_36 chr8:10513965-10514045 9.6e-05 65_[+2]_7 chr22:39632614-39632694 9.6e-05 23_[+2]_49 chr17:57635556-57635636 9.6e-05 11_[+2]_61 chr21:40467210-40467290 9.6e-05 53_[+2]_19 chr17:64538051-64538131 9.6e-05 6_[+2]_66 chr3:170731724-170731804 9.6e-05 34_[+2]_38 chr5:112267345-112267425 9.6e-05 31_[+2]_41 chr4:114558204-114558284 9.6e-05 45_[+2]_27 chr2:9105867-9105947 0.00011 37_[+2]_35 chr12:13589984-13590064 0.00013 32_[+2]_40 chr12:4430043-4430123 0.00013 30_[+2]_42 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif WAACCACA MEME-2 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF WAACCACA width=8 seqs=35 chr16:1001900-1001980 ( 39) AAACCACA 1 chr19:2974636-2974716 ( 22) AAACCACA 1 chr2:109830635-109830715 ( 57) AAACCACA 1 chr7:108056800-108056880 ( 47) AAACCACA 1 chr5:131439429-131439509 ( 68) AAACCACA 1 chr17:72711380-72711460 ( 72) AAACCACA 1 chr3:142569292-142569372 ( 35) AAACCACA 1 chr3:20145945-20146025 ( 36) AAACCACA 1 chr10:97278288-97278368 ( 62) AAACCACA 1 chr10:35736749-35736829 ( 15) AAACCACA 1 chr16:28006869-28006949 ( 49) AAACCACA 1 chr6:107860743-107860823 ( 43) TAACCACA 1 chr6:130088430-130088510 ( 26) TAACCACA 1 chr17:4110432-4110512 ( 24) TAACCACA 1 chr19:54714758-54714838 ( 2) TAACCACA 1 chr10:121545758-12154583 ( 37) TAACCACA 1 chr9:126817193-126817273 ( 20) TAACCACA 1 chr10:105264213-10526429 ( 16) AGACCACA 1 chr12:132111994-13211207 ( 15) AGACCACA 1 chr16:374574-374654 ( 32) AGACCACA 1 chr1:59280981-59281061 ( 61) AAGCCACA 1 chr6:43359347-43359427 ( 7) AAGCCACA 1 chr8:12400653-12400733 ( 30) AAGCCACA 1 chr21:46529817-46529897 ( 37) AAGCCACA 1 chr8:10513965-10514045 ( 66) AAACCGCA 1 chr22:39632614-39632694 ( 24) AAACCGCA 1 chr17:57635556-57635636 ( 12) AAACCGCA 1 chr21:40467210-40467290 ( 54) TGACCACA 1 chr17:64538051-64538131 ( 7) TGACCACA 1 chr3:170731724-170731804 ( 35) AAACCGCA 1 chr5:112267345-112267425 ( 32) TGACCACA 1 chr4:114558204-114558284 ( 46) TGACCACA 1 chr2:9105867-9105947 ( 38) TAGCCACA 1 chr12:13589984-13590064 ( 33) CAACCACA 1 chr12:4430043-4430123 ( 31) CAACCACA 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif WAACCACA MEME-2 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 11.0506 E= 8.8e-013 136 -220 -1177 34 171 -1177 -30 -1177 181 -1177 -78 -1177 -1177 193 -1177 -1177 -1177 193 -1177 -1177 186 -1177 -110 -1177 -1177 193 -1177 -1177 203 -1177 -1177 -1177 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif WAACCACA MEME-2 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 35 E= 8.8e-013 0.628571 0.057143 0.000000 0.314286 0.800000 0.000000 0.200000 0.000000 0.857143 0.000000 0.142857 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.885714 0.000000 0.114286 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif WAACCACA MEME-2 regular expression -------------------------------------------------------------------------------- [AT][AG]ACCACA -------------------------------------------------------------------------------- Time 9.34 secs. ******************************************************************************** ******************************************************************************** MOTIF YTGYGGTT MEME-3 width = 8 sites = 55 llr = 438 E-value = 6.6e-014 ******************************************************************************** -------------------------------------------------------------------------------- Motif YTGYGGTT MEME-3 Description -------------------------------------------------------------------------------- Simplified A 1::1:::: pos.-specific C 6::3::12 probability G ::a:aa:1 matrix T 3a:6::97 bits 2.0 ** ** 1.8 ** ** 1.6 ** ** 1.4 ** *** Relative 1.2 ** *** Entropy 1.0 ** *** (11.5 bits) 0.8 ** **** 0.6 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel CTGTGGTT consensus T C C sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YTGYGGTT MEME-3 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr3:148869809-148869889 19 1.48e-05 AATGGCCTGC CTGTGGTT TTCTGTTGCT chrX:129890421-129890501 43 1.48e-05 GGGATGCTGT CTGTGGTT GCTGTAACTG chr9:130150787-130150867 17 1.48e-05 GAGGCCTCTG CTGTGGTT ACCTCATCGC chr6:101396775-101396855 47 1.48e-05 tctcatactt ctgtggtt ttgcctacaa chr11:118187490-11818757 7 1.48e-05 GGCGGG CTGTGGTT AAGCAGTGCA chr1:35896861-35896941 64 1.48e-05 TTTATGGTTT CTGTGGTT TCTCTACTG chr9:126817193-126817273 69 1.48e-05 CCCTTCTTTG CTGTGGTT TCCT chr2:48211340-48211420 22 1.48e-05 CTGTTTAAGG CTGTGGTT TAACTGAGGG chrX:109965536-109965616 38 1.48e-05 gttccagcct ctgtggtt ttgctttttt chr14:100288218-10028829 15 1.48e-05 GGGAATGTAT CTGTGGTT AGATAGCTAG chr6:25974284-25974364 28 2.87e-05 atctcaattt ttgtggtt caggaatctg chr19:55471341-55471421 30 2.87e-05 TGTTTTTGAA TTGTGGTT TCTTATCAGT chr8:70815904-70815984 20 2.87e-05 tgtttgtttt ttgtggtt ttttttttga chr18:12337069-12337149 9 2.87e-05 TGTTTACT TTGTGGTT ACTGACAGAC chr7:73037433-73037513 38 4.43e-05 AGCTGGGCGG CTGCGGTT GGGGGCAGGC chr5:107955700-107955780 27 4.43e-05 tgcatgagcc ctgcggtt tgttacgccc chr18:46131844-46131924 12 4.43e-05 AGCCTGCTCC CTGCGGTT GTATCTGGCT chr18:499633-499713 38 4.43e-05 GATGCCTCCG CTGCGGTT ACTTATCTCA chr14:71353541-71353621 25 7.46e-05 attcagtttc ttgcggtt gggggactga chr1:165362413-165362493 35 7.46e-05 ggtctgtggt ctgtggtc tgtggtcAGA chr2:38779500-38779580 21 7.46e-05 aatcttgatt ctgtggtc ttcagtattg chr6:151183040-151183120 20 7.46e-05 ggaggcctct ttgcggtt gagataaggg chr17:76136252-76136332 28 7.46e-05 tggcgcgtgc ctgtggtc acagctattc chr3:171824904-171824984 67 7.46e-05 TGTGAAGCAC TTGCGGTT TTAGTG chr3:45615749-45615829 40 7.46e-05 actgaaacaa ttgcggtt catcccacag chr11:108094323-10809440 49 1.04e-04 TAATCTTGAC CTGTGGTG AGCACTCGTG chr3:58457212-58457292 59 1.04e-04 GCACAGAAGG CTGTGGTG TCAAATCAAA chr2:46361843-46361923 22 1.04e-04 agtgacttgc ttgtggtc acTCTGTCCT chr1:156896109-156896189 27 1.04e-04 caaggatcaa ctgtggtg gagaatctgc chr6:170404946-170405026 40 1.04e-04 GGCCTGAGCT TTGTGGTC TGGCGGGGCC chr2:109830635-109830715 41 1.18e-04 agctgtcagc atgtggtt tatgggtaaa chr1:184899951-184900031 57 1.18e-04 CCATAAAGGG ATGTGGTT CAACCAATTA chr3:133175006-133175086 38 1.49e-04 TTTGAGGCAT CTGCGGTC AGGAACTTTA chr1:229284004-229284084 68 1.49e-04 GCTCAGTGGG CTGCGGTC CTGGG chr13:22562082-22562162 55 1.49e-04 TGACGGGTGC CTGCGGTC AACCCCAGAT chr6:90031439-90031519 20 1.49e-04 cagaaccact ctgcggtc agtggtcact chr20:47654645-47654725 40 1.49e-04 taggtttttg CTGAGGTT AACCTCTTAT chr7:6261068-6261148 26 1.78e-04 cctgataact ttgtggtg atggaacagt chr1:9470998-9471078 12 1.78e-04 GTTTGGGGAT TTGTGGTG TCAGGAAACA chr1:110268294-110268374 12 2.23e-04 gccgtgctcc ttgaggtt atctactggg chr8:56852607-56852687 59 2.23e-04 AGAAGAGCTC TTGAGGTT TCTTAGTACA chr3:37824244-37824324 31 2.23e-04 ACAAGGGAAT TTGAGGTT TTACTGTTTT chr11:46358486-46358566 22 2.23e-04 gaattcgagg ctgcggtg agccacaatt chr4:142063796-142063876 45 2.38e-04 gccatatctg atgcggtt gaccacggcc chr6:149461268-149461348 29 2.52e-04 CATTGTCACT TTGTGGCT TGACTTTGCA chr7:1781851-1781931 39 2.52e-04 GTGATTACGA TTGTGGCT GAGGCGCCAC chr1:109159831-109159911 73 2.52e-04 attatctgac ttgtggct chr4:113437681-113437761 6 2.84e-04 TCAAG CTGCGGCT GTTGTCGCCG chr16:86959178-86959258 31 2.84e-04 GGCTTGCAGG CTGCGGCT CCTGGCTGTC chr9:77642631-77642711 58 3.14e-04 TAATCTGATC CTGAGGTC AGAAGACACG chr13:42570225-42570305 67 3.59e-04 GCAGTGCAGA CTGTGGCC TGGAAA chr1:63869215-63869295 68 3.59e-04 tctgagaaat gtgtggtt aggtg chr17:63225262-63225342 47 3.88e-04 CCCATAAATA CTGGGGTT GCTGACTCAT chr21:43348983-43349063 64 3.88e-04 TATGGTGAGG ATGTGGTG GGGGCACGA chr10:49514398-49514478 30 4.46e-04 CGCCAACCAG ATGCGGTC CCCTGGGGCC -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YTGYGGTT MEME-3 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr3:148869809-148869889 1.5e-05 18_[+3]_54 chrX:129890421-129890501 1.5e-05 42_[+3]_30 chr9:130150787-130150867 1.5e-05 16_[+3]_56 chr6:101396775-101396855 1.5e-05 46_[+3]_26 chr11:118187490-11818757 1.5e-05 6_[+3]_66 chr1:35896861-35896941 1.5e-05 63_[+3]_9 chr9:126817193-126817273 1.5e-05 68_[+3]_4 chr2:48211340-48211420 1.5e-05 21_[+3]_51 chrX:109965536-109965616 1.5e-05 37_[+3]_35 chr14:100288218-10028829 1.5e-05 14_[+3]_58 chr6:25974284-25974364 2.9e-05 27_[+3]_45 chr19:55471341-55471421 2.9e-05 29_[+3]_43 chr8:70815904-70815984 2.9e-05 19_[+3]_53 chr18:12337069-12337149 2.9e-05 8_[+3]_64 chr7:73037433-73037513 4.4e-05 37_[+3]_35 chr5:107955700-107955780 4.4e-05 26_[+3]_46 chr18:46131844-46131924 4.4e-05 11_[+3]_61 chr18:499633-499713 4.4e-05 37_[+3]_35 chr14:71353541-71353621 7.5e-05 24_[+3]_48 chr1:165362413-165362493 7.5e-05 34_[+3]_38 chr2:38779500-38779580 7.5e-05 20_[+3]_52 chr6:151183040-151183120 7.5e-05 19_[+3]_53 chr17:76136252-76136332 7.5e-05 27_[+3]_45 chr3:171824904-171824984 7.5e-05 66_[+3]_6 chr3:45615749-45615829 7.5e-05 39_[+3]_33 chr11:108094323-10809440 0.0001 48_[+3]_24 chr3:58457212-58457292 0.0001 58_[+3]_14 chr2:46361843-46361923 0.0001 21_[+3]_51 chr1:156896109-156896189 0.0001 26_[+3]_46 chr6:170404946-170405026 0.0001 39_[+3]_33 chr2:109830635-109830715 0.00012 40_[+3]_32 chr1:184899951-184900031 0.00012 56_[+3]_16 chr3:133175006-133175086 0.00015 37_[+3]_35 chr1:229284004-229284084 0.00015 67_[+3]_5 chr13:22562082-22562162 0.00015 54_[+3]_18 chr6:90031439-90031519 0.00015 19_[+3]_53 chr20:47654645-47654725 0.00015 39_[+3]_33 chr7:6261068-6261148 0.00018 25_[+3]_47 chr1:9470998-9471078 0.00018 11_[+3]_61 chr1:110268294-110268374 0.00022 11_[+3]_61 chr8:56852607-56852687 0.00022 58_[+3]_14 chr3:37824244-37824324 0.00022 30_[+3]_42 chr11:46358486-46358566 0.00022 21_[+3]_51 chr4:142063796-142063876 0.00024 44_[+3]_28 chr6:149461268-149461348 0.00025 28_[+3]_44 chr7:1781851-1781931 0.00025 38_[+3]_34 chr1:109159831-109159911 0.00025 72_[+3] chr4:113437681-113437761 0.00028 5_[+3]_67 chr16:86959178-86959258 0.00028 30_[+3]_42 chr9:77642631-77642711 0.00031 57_[+3]_15 chr13:42570225-42570305 0.00036 66_[+3]_6 chr1:63869215-63869295 0.00036 67_[+3]_5 chr17:63225262-63225342 0.00039 46_[+3]_26 chr21:43348983-43349063 0.00039 63_[+3]_9 chr10:49514398-49514478 0.00045 29_[+3]_43 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YTGYGGTT MEME-3 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF YTGYGGTT width=8 seqs=55 chr3:148869809-148869889 ( 19) CTGTGGTT 1 chrX:129890421-129890501 ( 43) CTGTGGTT 1 chr9:130150787-130150867 ( 17) CTGTGGTT 1 chr6:101396775-101396855 ( 47) CTGTGGTT 1 chr11:118187490-11818757 ( 7) CTGTGGTT 1 chr1:35896861-35896941 ( 64) CTGTGGTT 1 chr9:126817193-126817273 ( 69) CTGTGGTT 1 chr2:48211340-48211420 ( 22) CTGTGGTT 1 chrX:109965536-109965616 ( 38) CTGTGGTT 1 chr14:100288218-10028829 ( 15) CTGTGGTT 1 chr6:25974284-25974364 ( 28) TTGTGGTT 1 chr19:55471341-55471421 ( 30) TTGTGGTT 1 chr8:70815904-70815984 ( 20) TTGTGGTT 1 chr18:12337069-12337149 ( 9) TTGTGGTT 1 chr7:73037433-73037513 ( 38) CTGCGGTT 1 chr5:107955700-107955780 ( 27) CTGCGGTT 1 chr18:46131844-46131924 ( 12) CTGCGGTT 1 chr18:499633-499713 ( 38) CTGCGGTT 1 chr14:71353541-71353621 ( 25) TTGCGGTT 1 chr1:165362413-165362493 ( 35) CTGTGGTC 1 chr2:38779500-38779580 ( 21) CTGTGGTC 1 chr6:151183040-151183120 ( 20) TTGCGGTT 1 chr17:76136252-76136332 ( 28) CTGTGGTC 1 chr3:171824904-171824984 ( 67) TTGCGGTT 1 chr3:45615749-45615829 ( 40) TTGCGGTT 1 chr11:108094323-10809440 ( 49) CTGTGGTG 1 chr3:58457212-58457292 ( 59) CTGTGGTG 1 chr2:46361843-46361923 ( 22) TTGTGGTC 1 chr1:156896109-156896189 ( 27) CTGTGGTG 1 chr6:170404946-170405026 ( 40) TTGTGGTC 1 chr2:109830635-109830715 ( 41) ATGTGGTT 1 chr1:184899951-184900031 ( 57) ATGTGGTT 1 chr3:133175006-133175086 ( 38) CTGCGGTC 1 chr1:229284004-229284084 ( 68) CTGCGGTC 1 chr13:22562082-22562162 ( 55) CTGCGGTC 1 chr6:90031439-90031519 ( 20) CTGCGGTC 1 chr20:47654645-47654725 ( 40) CTGAGGTT 1 chr7:6261068-6261148 ( 26) TTGTGGTG 1 chr1:9470998-9471078 ( 12) TTGTGGTG 1 chr1:110268294-110268374 ( 12) TTGAGGTT 1 chr8:56852607-56852687 ( 59) TTGAGGTT 1 chr3:37824244-37824324 ( 31) TTGAGGTT 1 chr11:46358486-46358566 ( 22) CTGCGGTG 1 chr4:142063796-142063876 ( 45) ATGCGGTT 1 chr6:149461268-149461348 ( 29) TTGTGGCT 1 chr7:1781851-1781931 ( 39) TTGTGGCT 1 chr1:109159831-109159911 ( 73) TTGTGGCT 1 chr4:113437681-113437761 ( 6) CTGCGGCT 1 chr16:86959178-86959258 ( 31) CTGCGGCT 1 chr9:77642631-77642711 ( 58) CTGAGGTC 1 chr13:42570225-42570305 ( 67) CTGTGGCC 1 chr1:63869215-63869295 ( 68) GTGTGGTT 1 chr17:63225262-63225342 ( 47) CTGGGGTT 1 chr21:43348983-43349063 ( 64) ATGTGGTG 1 chr10:49514398-49514478 ( 30) ATGCGGTC 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YTGYGGTT MEME-3 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 9.58084 E= 6.6e-014 -143 110 -375 40 -1243 -1243 -1243 201 -1243 -1243 202 -1243 -143 24 -375 123 -1243 -1243 202 -1243 -1243 -1243 202 -1243 -1243 -126 -1243 185 -1243 -26 -95 140 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YTGYGGTT MEME-3 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 55 E= 6.6e-014 0.090909 0.563636 0.018182 0.327273 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.090909 0.309091 0.018182 0.581818 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.109091 0.000000 0.890909 0.000000 0.218182 0.127273 0.654545 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YTGYGGTT MEME-3 regular expression -------------------------------------------------------------------------------- [CT]TG[TC]GGT[TC] -------------------------------------------------------------------------------- Time 12.97 secs. ******************************************************************************** ******************************************************************************** MOTIF YCTTATCT MEME-4 width = 8 sites = 53 llr = 425 E-value = 8.7e-014 ******************************************************************************** -------------------------------------------------------------------------------- Motif YCTTATCT MEME-4 Description -------------------------------------------------------------------------------- Simplified A 1::2a::2 pos.-specific C 37::::a: probability G 22:::::: matrix T 52a8:a:8 bits 2.0 * *** 1.8 * *** 1.6 * *** 1.4 ***** Relative 1.2 ****** Entropy 1.0 ****** (11.6 bits) 0.8 ******* 0.6 ******* 0.4 ******* 0.2 ******** 0.0 -------- Multilevel TCTTATCT consensus C A sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YCTTATCT MEME-4 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr17:549352-549432 42 1.58e-05 CTGATAAGGG TCTTATCT TTTCTAATTC chr5:133023042-133023122 7 1.58e-05 agcccc tcttatct gccaaacact chr6:101396775-101396855 32 1.58e-05 ctacctcagt tcttatct catacttctg chr20:47654645-47654725 52 1.58e-05 GAGGTTAACC TCTTATCT CTTGTCCCTC chr9:138876744-138876824 36 1.58e-05 CTCACACGGG TCTTATCT GTTCTTATCC chr3:98270672-98270752 42 1.58e-05 TCCTCAGGCT TCTTATCT AAGTAGTGCC chr19:5894559-5894639 44 1.58e-05 GGGGGCCTTA TCTTATCT CCCTTCCTCA chr1:12015436-12015516 49 1.58e-05 gactcagttt tcttatct ttacaaaagg chr5:95997547-95997627 58 3.24e-05 TGATCCGCTT CCTTATCT AGACTGTCCA chr17:72159816-72159896 40 3.24e-05 gtcttcactt ccttatct ctcgttccct chr7:86741370-86741450 7 3.24e-05 TCAGGC CCTTATCT TATATGGCTC chr6:159920179-159920259 53 3.24e-05 tccatttcac ccttatct atagggtgca chr12:4430043-4430123 56 3.24e-05 GCGCCGGCTT CCTTATCT GCCCCGAACG chr9:126817193-126817273 42 3.24e-05 GGTTCTGAGT CCTTATCT TGGCCCTGGC chr8:96143618-96143698 60 6.37e-05 caaagagctg tcttatca cttgacttga chr19:55471341-55471421 38 6.37e-05 AATTGTGGTT TCTTATCA GTTCATCCGA chr17:42061333-42061413 9 6.37e-05 GGTCGCGC GCTTATCT CCCGCAAACA chr14:104625328-10462540 6 6.37e-05 GGGCG TCTTATCA GCGCCGGCCC chrX:109965536-109965616 16 6.37e-05 TCACTTTTGT GCTTATCT gtttgttcca chr1:53581725-53581805 46 6.37e-05 GCCACGCTCC TCTTATCA TTAGATTCCA chr8:97222446-97222526 40 6.37e-05 TCAGTCCACA GCTTATCT CTCATAACTA chr6:25974284-25974364 14 7.85e-05 aacactgata tgttatct caatttttgt chr7:22341490-22341570 58 7.85e-05 CTTGCCAGCT TGTTATCT GTATGAACTG chr12:27996755-27996835 31 7.85e-05 ATGGCTCTTC TGTTATCT ACAAAATATT chr2:38779500-38779580 58 7.85e-05 tctagattgg tgttatct tccctttgac chr20:20213815-20213895 35 9.34e-05 TAATTAGGCT TTTTATCT TTACATTTGT chr13:22562082-22562162 3 9.34e-05 AA TTTTATCT ATGATTGTCA chr10:81293625-81293705 30 9.34e-05 tgacttgggg ttttatct gttgacatag chr8:124526623-124526703 4 1.09e-04 TCC TCTAATCT TCACTTTTGA chr6:170595922-170596002 55 1.09e-04 CCCGGAGAGA TCTAATCT ATGGCACGCG chr4:1633939-1634019 41 1.09e-04 tcggtcctaa tctaatct gacctgtgtc chr9:136734916-136734996 7 1.25e-04 GACCTT CCTTATCA GCCATTACCA chr1:181120803-181120883 32 1.25e-04 gaactctcca ccttatca cctccatgga chr7:44331157-44331237 6 1.25e-04 ATGTG CCTTATCA GCACGGGAGT chr1:75889384-75889464 2 1.41e-04 C ACTTATCT GTTTACTAGC chr18:499633-499713 46 1.41e-04 CGCTGCGGTT ACTTATCT CATACATAAA chr3:133175006-133175086 51 1.72e-04 CGGTCAGGAA CTTTATCT GAGCTGTAAC chr11:33907046-33907126 26 1.72e-04 TGGGATGTGG CTTTATCT CTGTGTACAT chr2:170972521-170972601 7 1.72e-04 tattgc ctttatct atggacgtgc chr11:62269948-62270028 30 1.88e-04 TGATAAGATG GCttatca agtttctgcc chr16:69459204-69459284 67 2.04e-04 TTTTTTTCCC CCTAATCT GAGTTG chr16:19407081-19407161 57 2.34e-04 gtagggcctc ggttatct attggtccag chr16:374574-374654 22 2.34e-04 GCGCTTCCAG TGTTATCA CAAGACCACA chr18:46131844-46131924 59 2.34e-04 TGTGTGAAGA GGTTATCT GCTGCTACCA chr6:150400060-150400140 4 2.34e-04 gtt ggttatct ttgtctatgt chr1:3111284-3111364 61 2.63e-04 CAGTCCCACG TTTTATCA TCTAAACGCC chr22:48486000-48486080 46 2.63e-04 TTTTGTTTTG TTTTATCA CATGTCAGAA chr9:77642631-77642711 46 2.94e-04 AGGCAGGAGA GCTAATCT GATCCTGAGG chr9:116058676-116058756 48 2.94e-04 accacgccca gctaatct ttgctgggga chr11:1804325-1804405 14 3.09e-04 actgtgtttg tgtaatct gccacagcag chr6:90031439-90031519 35 3.39e-04 gtcagtggtc acttatca ggaaggaatg chr17:72711380-72711460 28 4.16e-04 CCCCTCACAC CCTAATCA GGAATGAGTG chr19:13162530-13162610 63 4.46e-04 GACCAGCGAT ACTAATCT GTGTCAACAG -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YCTTATCT MEME-4 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr17:549352-549432 1.6e-05 41_[+4]_31 chr5:133023042-133023122 1.6e-05 6_[+4]_66 chr6:101396775-101396855 1.6e-05 31_[+4]_41 chr20:47654645-47654725 1.6e-05 51_[+4]_21 chr9:138876744-138876824 1.6e-05 35_[+4]_37 chr3:98270672-98270752 1.6e-05 41_[+4]_31 chr19:5894559-5894639 1.6e-05 43_[+4]_29 chr1:12015436-12015516 1.6e-05 48_[+4]_24 chr5:95997547-95997627 3.2e-05 57_[+4]_15 chr17:72159816-72159896 3.2e-05 39_[+4]_33 chr7:86741370-86741450 3.2e-05 6_[+4]_66 chr6:159920179-159920259 3.2e-05 52_[+4]_20 chr12:4430043-4430123 3.2e-05 55_[+4]_17 chr9:126817193-126817273 3.2e-05 41_[+4]_31 chr8:96143618-96143698 6.4e-05 59_[+4]_13 chr19:55471341-55471421 6.4e-05 37_[+4]_35 chr17:42061333-42061413 6.4e-05 8_[+4]_64 chr14:104625328-10462540 6.4e-05 5_[+4]_67 chrX:109965536-109965616 6.4e-05 15_[+4]_57 chr1:53581725-53581805 6.4e-05 45_[+4]_27 chr8:97222446-97222526 6.4e-05 39_[+4]_33 chr6:25974284-25974364 7.8e-05 13_[+4]_59 chr7:22341490-22341570 7.8e-05 57_[+4]_15 chr12:27996755-27996835 7.8e-05 30_[+4]_42 chr2:38779500-38779580 7.8e-05 57_[+4]_15 chr20:20213815-20213895 9.3e-05 34_[+4]_38 chr13:22562082-22562162 9.3e-05 2_[+4]_70 chr10:81293625-81293705 9.3e-05 29_[+4]_43 chr8:124526623-124526703 0.00011 3_[+4]_69 chr6:170595922-170596002 0.00011 54_[+4]_18 chr4:1633939-1634019 0.00011 40_[+4]_32 chr9:136734916-136734996 0.00013 6_[+4]_66 chr1:181120803-181120883 0.00013 31_[+4]_41 chr7:44331157-44331237 0.00013 5_[+4]_67 chr1:75889384-75889464 0.00014 1_[+4]_71 chr18:499633-499713 0.00014 45_[+4]_27 chr3:133175006-133175086 0.00017 50_[+4]_22 chr11:33907046-33907126 0.00017 25_[+4]_47 chr2:170972521-170972601 0.00017 6_[+4]_66 chr11:62269948-62270028 0.00019 29_[+4]_43 chr16:69459204-69459284 0.0002 66_[+4]_6 chr16:19407081-19407161 0.00023 56_[+4]_16 chr16:374574-374654 0.00023 21_[+4]_51 chr18:46131844-46131924 0.00023 58_[+4]_14 chr6:150400060-150400140 0.00023 3_[+4]_69 chr1:3111284-3111364 0.00026 60_[+4]_12 chr22:48486000-48486080 0.00026 45_[+4]_27 chr9:77642631-77642711 0.00029 45_[+4]_27 chr9:116058676-116058756 0.00029 47_[+4]_25 chr11:1804325-1804405 0.00031 13_[+4]_59 chr6:90031439-90031519 0.00034 34_[+4]_38 chr17:72711380-72711460 0.00042 27_[+4]_45 chr19:13162530-13162610 0.00045 62_[+4]_10 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YCTTATCT MEME-4 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF YCTTATCT width=8 seqs=53 chr17:549352-549432 ( 42) TCTTATCT 1 chr5:133023042-133023122 ( 7) TCTTATCT 1 chr6:101396775-101396855 ( 32) TCTTATCT 1 chr20:47654645-47654725 ( 52) TCTTATCT 1 chr9:138876744-138876824 ( 36) TCTTATCT 1 chr3:98270672-98270752 ( 42) TCTTATCT 1 chr19:5894559-5894639 ( 44) TCTTATCT 1 chr1:12015436-12015516 ( 49) TCTTATCT 1 chr5:95997547-95997627 ( 58) CCTTATCT 1 chr17:72159816-72159896 ( 40) CCTTATCT 1 chr7:86741370-86741450 ( 7) CCTTATCT 1 chr6:159920179-159920259 ( 53) CCTTATCT 1 chr12:4430043-4430123 ( 56) CCTTATCT 1 chr9:126817193-126817273 ( 42) CCTTATCT 1 chr8:96143618-96143698 ( 60) TCTTATCA 1 chr19:55471341-55471421 ( 38) TCTTATCA 1 chr17:42061333-42061413 ( 9) GCTTATCT 1 chr14:104625328-10462540 ( 6) TCTTATCA 1 chrX:109965536-109965616 ( 16) GCTTATCT 1 chr1:53581725-53581805 ( 46) TCTTATCA 1 chr8:97222446-97222526 ( 40) GCTTATCT 1 chr6:25974284-25974364 ( 14) TGTTATCT 1 chr7:22341490-22341570 ( 58) TGTTATCT 1 chr12:27996755-27996835 ( 31) TGTTATCT 1 chr2:38779500-38779580 ( 58) TGTTATCT 1 chr20:20213815-20213895 ( 35) TTTTATCT 1 chr13:22562082-22562162 ( 3) TTTTATCT 1 chr10:81293625-81293705 ( 30) TTTTATCT 1 chr8:124526623-124526703 ( 4) TCTAATCT 1 chr6:170595922-170596002 ( 55) TCTAATCT 1 chr4:1633939-1634019 ( 41) TCTAATCT 1 chr9:136734916-136734996 ( 7) CCTTATCA 1 chr1:181120803-181120883 ( 32) CCTTATCA 1 chr7:44331157-44331237 ( 6) CCTTATCA 1 chr1:75889384-75889464 ( 2) ACTTATCT 1 chr18:499633-499713 ( 46) ACTTATCT 1 chr3:133175006-133175086 ( 51) CTTTATCT 1 chr11:33907046-33907126 ( 26) CTTTATCT 1 chr2:170972521-170972601 ( 7) CTTTATCT 1 chr11:62269948-62270028 ( 30) GCTTATCA 1 chr16:69459204-69459284 ( 67) CCTAATCT 1 chr16:19407081-19407161 ( 57) GGTTATCT 1 chr16:374574-374654 ( 22) TGTTATCA 1 chr18:46131844-46131924 ( 59) GGTTATCT 1 chr6:150400060-150400140 ( 4) GGTTATCT 1 chr1:3111284-3111364 ( 61) TTTTATCA 1 chr22:48486000-48486080 ( 46) TTTTATCA 1 chr9:77642631-77642711 ( 46) GCTAATCT 1 chr9:116058676-116058756 ( 48) GCTAATCT 1 chr11:1804325-1804405 ( 14) TGTAATCT 1 chr6:90031439-90031519 ( 35) ACTTATCA 1 chr17:72711380-72711460 ( 28) CCTAATCA 1 chr19:13162530-13162610 ( 63) ACTAATCT 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YCTTATCT MEME-4 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 10.0668 E= 8.7e-014 -170 1 -53 99 -1237 137 -53 -71 -1237 -1237 -1237 201 -53 -1237 -1237 175 203 -1237 -1237 -1237 -1237 -1237 -1237 201 -1237 193 -1237 -1237 0 -1237 -1237 161 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YCTTATCT MEME-4 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 53 E= 8.7e-014 0.075472 0.264151 0.169811 0.490566 0.000000 0.679245 0.169811 0.150943 0.000000 0.000000 0.000000 1.000000 0.169811 0.000000 0.000000 0.830189 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 0.245283 0.000000 0.000000 0.754717 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YCTTATCT MEME-4 regular expression -------------------------------------------------------------------------------- [TC]CTTATC[TA] -------------------------------------------------------------------------------- Time 16.45 secs. ******************************************************************************** ******************************************************************************** MOTIF CACGTGSC MEME-5 width = 8 sites = 41 llr = 335 E-value = 2.5e-005 ******************************************************************************** -------------------------------------------------------------------------------- Motif CACGTGSC MEME-5 Description -------------------------------------------------------------------------------- Simplified A :7:::::2 pos.-specific C a1a:2:48 probability G :2:a:a4: matrix T ::::8:2: bits 2.0 * ** * 1.8 * ** * 1.6 * ** * 1.4 * ** * Relative 1.2 * **** * Entropy 1.0 ****** * (11.8 bits) 0.8 ****** * 0.6 ****** * 0.4 ******** 0.2 ******** 0.0 -------- Multilevel CACGTGCC consensus GA sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CACGTGSC MEME-5 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr17:17109799-17109879 28 1.73e-05 cgtgccaggc cacgtgcc aggccacgcc chr10:49514398-49514478 57 1.73e-05 CACGCGCCGC CACGTGCC GCCACAGGGC chr20:47654645-47654725 10 1.73e-05 gattacagg cacgtgcc accatgccca chr14:23025411-23025491 56 1.73e-05 CGCCCCAGGC CACGTGCC GAGGGGAGCA chr10:97278288-97278368 37 1.73e-05 CACACAAAAA CACGTGCC AGTTAGAACC chr11:62269948-62270028 47 1.73e-05 aagtttctgc cacgtgcc atgtgcctgg chr2:9105867-9105947 62 1.73e-05 TCAACTGCCA CACGTGCC CAACAAAAGC chr16:1001900-1001980 64 3.36e-05 ACAAGCATTG CACGTGGC CCCAGGCCT chr19:17828334-17828414 65 3.36e-05 TGGTAGACGG CACGTGGC CAGTGGCT chr3:171824904-171824984 10 3.36e-05 ACAAGTGCC CACGTGGC AGCCTTTCCC chr1:61557372-61557452 22 3.36e-05 ATATACCCGG CACGTGGC AAGGTCACAA chr10:35736749-35736829 4 3.36e-05 AAA CACGTGGC TGTAAACCAC chr21:47451500-47451580 47 5.00e-05 agagctgtgg cacgtgtc agtacctcac chr17:80101381-80101461 41 5.00e-05 cacgcacaca cacGTGTC AGGGAGCACg chr3:98270672-98270752 59 5.00e-05 TAAGTAGTGC CACGTGTC AAGTCcaagg chr18:9082088-9082168 49 5.00e-05 ggaccacagg cacgtgtc actatgactg chr16:11706375-11706455 64 6.62e-05 TCAGGACGCT CACGTGCA CAGAGAACC chr16:90235246-90235326 71 8.14e-05 CAGCCCCTCC CACGTGGA CA chr17:72159816-72159896 69 8.14e-05 cttactgctc cacgtgga gtaa chr20:46153259-46153339 42 8.14e-05 gacttgggca cacgtgga gtggttttaa chr8:124526623-124526703 31 8.14e-05 AGTCCCATGA CACGTGGA TACAGACTGA chr17:64538051-64538131 46 8.14e-05 AACAAGCCAC CACGTGGA ATCTCACAGT chr3:48701107-48701187 45 1.17e-04 TAACTCCTGG CACGCGCC GGTCTCGCCA chr15:89560855-89560935 21 1.17e-04 CACCGTTGGC CACGCGCC TCGGTCTCTA chr1:209848511-209848591 10 1.17e-04 TGGCCTTCC CACGCGCC CCGCTGCGAT chr3:128292890-128292970 43 1.17e-04 GTCCACGAGC CACGCGCC AAGGGCAGTT chr1:16521757-16521837 10 1.17e-04 cgtggacat cgcgtgcc tcctggcatc chr8:56852607-56852687 14 1.51e-04 CAGGCCTGGA CGCGTGGC AGCGATGCCG chr17:549352-549432 18 1.51e-04 TCTCGGTGAC CGCGTGGC CTCTGCCTGA chr5:136015032-136015112 35 1.51e-04 AAAAATGTCA CACGCGGC TGGGACAGAT chr21:47712963-47713043 68 1.84e-04 gttagcctga cccgtgcc cggga chr21:47714555-47714635 30 1.84e-04 gttagcctga cccgtgcc cgggactcag chr3:193853799-193853879 18 2.36e-04 CGAGCGGTGC CGCGTGTC TCCTCCTCCC chrX:129259372-129259452 9 2.36e-04 TTTGTGTA CGCGTGTC TGTGCCCGCC chr7:4456185-4456265 15 2.36e-04 TTTCATAAAA CCCGTGGC AAAGTgaatg chr11:12136272-12136352 50 2.36e-04 GTTTCCTCAG CACGCGTC GGTCTGTAAA chr9:138876744-138876824 11 2.36e-04 cacagttcag cccgtggc aGTCACCCTC chr9:116058676-116058756 30 2.36e-04 ggattacagg cacgcgtc accacgccca chr5:95997547-95997627 6 2.69e-04 ACAGG CGCGTGCA CGCACGCACA chr4:170679182-170679262 46 2.69e-04 CCGTGCTGGG CGCGTGCA AGGAGCGTCT chr11:76092220-76092300 35 2.69e-04 AGCAGGCGGG CACGCGCA AGGAAGCGCG -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CACGTGSC MEME-5 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr17:17109799-17109879 1.7e-05 27_[+5]_45 chr10:49514398-49514478 1.7e-05 56_[+5]_16 chr20:47654645-47654725 1.7e-05 9_[+5]_63 chr14:23025411-23025491 1.7e-05 55_[+5]_17 chr10:97278288-97278368 1.7e-05 36_[+5]_36 chr11:62269948-62270028 1.7e-05 46_[+5]_26 chr2:9105867-9105947 1.7e-05 61_[+5]_11 chr16:1001900-1001980 3.4e-05 63_[+5]_9 chr19:17828334-17828414 3.4e-05 64_[+5]_8 chr3:171824904-171824984 3.4e-05 9_[+5]_63 chr1:61557372-61557452 3.4e-05 21_[+5]_51 chr10:35736749-35736829 3.4e-05 3_[+5]_69 chr21:47451500-47451580 5e-05 46_[+5]_26 chr17:80101381-80101461 5e-05 40_[+5]_32 chr3:98270672-98270752 5e-05 58_[+5]_14 chr18:9082088-9082168 5e-05 48_[+5]_24 chr16:11706375-11706455 6.6e-05 63_[+5]_9 chr16:90235246-90235326 8.1e-05 70_[+5]_2 chr17:72159816-72159896 8.1e-05 68_[+5]_4 chr20:46153259-46153339 8.1e-05 41_[+5]_31 chr8:124526623-124526703 8.1e-05 30_[+5]_42 chr17:64538051-64538131 8.1e-05 45_[+5]_27 chr3:48701107-48701187 0.00012 44_[+5]_28 chr15:89560855-89560935 0.00012 20_[+5]_52 chr1:209848511-209848591 0.00012 9_[+5]_63 chr3:128292890-128292970 0.00012 42_[+5]_30 chr1:16521757-16521837 0.00012 9_[+5]_63 chr8:56852607-56852687 0.00015 13_[+5]_59 chr17:549352-549432 0.00015 17_[+5]_55 chr5:136015032-136015112 0.00015 34_[+5]_38 chr21:47712963-47713043 0.00018 67_[+5]_5 chr21:47714555-47714635 0.00018 29_[+5]_43 chr3:193853799-193853879 0.00024 17_[+5]_55 chrX:129259372-129259452 0.00024 8_[+5]_64 chr7:4456185-4456265 0.00024 14_[+5]_58 chr11:12136272-12136352 0.00024 49_[+5]_23 chr9:138876744-138876824 0.00024 10_[+5]_62 chr9:116058676-116058756 0.00024 29_[+5]_43 chr5:95997547-95997627 0.00027 5_[+5]_67 chr4:170679182-170679262 0.00027 45_[+5]_27 chr11:76092220-76092300 0.00027 34_[+5]_38 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CACGTGSC MEME-5 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF CACGTGSC width=8 seqs=41 chr17:17109799-17109879 ( 28) CACGTGCC 1 chr10:49514398-49514478 ( 57) CACGTGCC 1 chr20:47654645-47654725 ( 10) CACGTGCC 1 chr14:23025411-23025491 ( 56) CACGTGCC 1 chr10:97278288-97278368 ( 37) CACGTGCC 1 chr11:62269948-62270028 ( 47) CACGTGCC 1 chr2:9105867-9105947 ( 62) CACGTGCC 1 chr16:1001900-1001980 ( 64) CACGTGGC 1 chr19:17828334-17828414 ( 65) CACGTGGC 1 chr3:171824904-171824984 ( 10) CACGTGGC 1 chr1:61557372-61557452 ( 22) CACGTGGC 1 chr10:35736749-35736829 ( 4) CACGTGGC 1 chr21:47451500-47451580 ( 47) CACGTGTC 1 chr17:80101381-80101461 ( 41) CACGTGTC 1 chr3:98270672-98270752 ( 59) CACGTGTC 1 chr18:9082088-9082168 ( 49) CACGTGTC 1 chr16:11706375-11706455 ( 64) CACGTGCA 1 chr16:90235246-90235326 ( 71) CACGTGGA 1 chr17:72159816-72159896 ( 69) CACGTGGA 1 chr20:46153259-46153339 ( 42) CACGTGGA 1 chr8:124526623-124526703 ( 31) CACGTGGA 1 chr17:64538051-64538131 ( 46) CACGTGGA 1 chr3:48701107-48701187 ( 45) CACGCGCC 1 chr15:89560855-89560935 ( 21) CACGCGCC 1 chr1:209848511-209848591 ( 10) CACGCGCC 1 chr3:128292890-128292970 ( 43) CACGCGCC 1 chr1:16521757-16521837 ( 10) CGCGTGCC 1 chr8:56852607-56852687 ( 14) CGCGTGGC 1 chr17:549352-549432 ( 18) CGCGTGGC 1 chr5:136015032-136015112 ( 35) CACGCGGC 1 chr21:47712963-47713043 ( 68) CCCGTGCC 1 chr21:47714555-47714635 ( 30) CCCGTGCC 1 chr3:193853799-193853879 ( 18) CGCGTGTC 1 chrX:129259372-129259452 ( 9) CGCGTGTC 1 chr7:4456185-4456265 ( 15) CCCGTGGC 1 chr11:12136272-12136352 ( 50) CACGCGTC 1 chr9:138876744-138876824 ( 11) CCCGTGGC 1 chr9:116058676-116058756 ( 30) CACGCGTC 1 chr5:95997547-95997627 ( 6) CGCGTGCA 1 chr4:170679182-170679262 ( 46) CGCGTGCA 1 chr11:76092220-76092300 ( 35) CACGCGCA 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CACGTGSC MEME-5 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 10.2866 E= 2.5e-005 -1200 193 -1200 -1200 158 -142 -53 -1200 -1200 193 -1200 -1200 -1200 -1200 202 -1200 -1200 -43 -1200 170 -1200 -1200 202 -1200 -1200 74 57 -34 -16 157 -1200 -1200 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CACGTGSC MEME-5 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 41 E= 2.5e-005 0.000000 1.000000 0.000000 0.000000 0.731707 0.097561 0.170732 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.195122 0.000000 0.804878 0.000000 0.000000 1.000000 0.000000 0.000000 0.439024 0.365854 0.195122 0.219512 0.780488 0.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CACGTGSC MEME-5 regular expression -------------------------------------------------------------------------------- CACGTG[CG][CA] -------------------------------------------------------------------------------- Time 19.91 secs. ******************************************************************************** ******************************************************************************** SUMMARY OF MOTIFS ******************************************************************************** -------------------------------------------------------------------------------- Combined block diagrams: non-overlapping sites with p-value < 0.0001 -------------------------------------------------------------------------------- SEQUENCE NAME COMBINED P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr4:142063796-142063876 5.25e-02 80 chr8:97222446-97222526 1.12e-02 39_[+4(6.37e-05)]_33 chr2:9105867-9105947 9.37e-04 61_[+5(1.73e-05)]_11 chr2:39444149-39444229 3.33e-02 80 chr4:114558204-114558284 3.10e-02 45_[+2(9.59e-05)]_3_[+2(9.59e-05)]_\ 16 chr9:116058676-116058756 2.96e-02 80 chr16:28135654-28135734 3.39e-02 32_[+1(1.32e-05)]_40 chr17:65330519-65330599 5.35e-02 80 chr16:28006869-28006949 3.77e-02 11_[+2(4.79e-05)]_29_[+2(1.59e-05)]_\ 24 chr18:9082088-9082168 3.33e-02 48_[+5(5.00e-05)]_24 chr1:53581725-53581805 1.55e-02 45_[+4(6.37e-05)]_27 chr11:62269948-62270028 7.83e-05 19_[+1(2.67e-05)]_19_[+5(1.73e-05)]_\ 26 chr1:12015436-12015516 4.03e-02 48_[+4(1.58e-05)]_24 chr5:154120680-154120760 3.32e-01 80 chr10:35736749-35736829 7.74e-05 3_[+5(3.36e-05)]_3_[+2(1.59e-05)]_\ 58 chr2:85934587-85934667 2.71e-01 80 chr18:499633-499713 3.14e-03 37_[+3(4.43e-05)]_35 chr2:135356100-135356180 7.70e-02 80 chr1:222885472-222885552 5.49e-01 80 chr6:170404946-170405026 9.18e-02 80 chr4:1633939-1634019 7.91e-03 80 chr6:41735027-41735107 6.40e-01 80 chr19:5894559-5894639 2.70e-02 43_[+4(1.58e-05)]_29 chr4:26320916-26320996 9.55e-01 80 chr1:109159831-109159911 2.21e-02 80 chr1:61557372-61557452 1.71e-02 21_[+5(3.36e-05)]_51 chr14:100288218-10028829 8.40e-03 14_[+3(1.48e-05)]_58 chr10:97278288-97278368 1.60e-05 36_[+5(1.73e-05)]_17_[+2(1.59e-05)]_\ 11 chr3:20145945-20146025 2.84e-02 14_[+2(9.59e-05)]_13_[+2(1.59e-05)]_\ 37 chr3:98270672-98270752 2.71e-03 41_[+4(1.58e-05)]_9_[+5(5.00e-05)]_\ 14 chr17:76623391-76623471 3.80e-02 80 chr1:212612429-212612509 8.56e-02 80 chrX:40709663-40709743 1.13e-01 80 chr16:19405161-19405241 2.67e-01 80 chr17:80101381-80101461 1.96e-01 40_[+5(5.00e-05)]_32 chr7:105284037-105284117 3.79e-01 80 chr21:43203826-43203906 2.08e-02 80 chr9:138876744-138876824 5.98e-03 35_[+4(1.58e-05)]_37 chr3:107725098-107725178 8.91e-02 80 chr6:37170776-37170856 2.92e-01 80 chr5:73622914-73622994 1.23e-01 80 chr3:195634840-195634920 1.32e-01 80 chr10:73103201-73103281 7.83e-01 80 chr16:86959178-86959258 1.13e-01 80 chr7:44331157-44331237 7.02e-02 80 chr21:47714555-47714635 3.65e-02 80 chr6:158826580-158826660 5.22e-01 80 chr5:112267345-112267425 1.28e-01 31_[+2(9.59e-05)]_41 chr8:3086489-3086569 1.92e-02 80 chr17:42767771-42767851 6.34e-03 68_[+1(5.41e-05)]_4 chr3:155546461-155546541 1.19e-03 46_[+1(1.32e-05)]_26 chr11:12136272-12136352 3.06e-01 80 chr8:142046295-142046375 4.58e-01 80 chr3:45615749-45615829 8.81e-03 18_[+1(9.57e-05)]_13_[+3(7.46e-05)]_\ 33 chr21:47451500-47451580 1.81e-02 46_[+5(5.00e-05)]_26 chr14:22966934-22967014 6.53e-02 26_[+1(1.32e-05)]_46 chrX:109965536-109965616 3.73e-03 15_[+4(6.37e-05)]_14_[+3(1.48e-05)]_\ 35 chr11:1804325-1804405 8.78e-02 80 chr6:150400060-150400140 1.38e-01 80 chr18:46131844-46131924 9.64e-03 11_[+3(4.43e-05)]_61 chr19:41857462-41857542 2.79e-01 80 chr1:59492293-59492373 2.53e-01 80 chr7:39775690-39775770 4.26e-01 80 chr2:24404892-24404972 7.19e-01 80 chr10:81293625-81293705 7.22e-02 29_[+4(9.34e-05)]_43 chr1:214176733-214176813 7.19e-01 80 chr5:107955700-107955780 1.37e-02 26_[+3(4.43e-05)]_46 chr22:48486000-48486080 2.04e-02 80 chr3:170731724-170731804 3.62e-02 34_[+2(9.59e-05)]_38 chr2:48211340-48211420 7.37e-05 21_[+3(1.48e-05)]_17_[+2(3.19e-05)]_\ 26 chr1:16521757-16521837 1.11e-02 80 chr9:126817193-126817273 3.20e-05 19_[+2(3.19e-05)]_14_[+4(3.24e-05)]_\ 19_[+3(1.48e-05)]_4 chr21:43348983-43349063 1.33e-01 80 chr17:64538051-64538131 2.89e-04 6_[+2(9.59e-05)]_17_[+1(9.57e-05)]_\ 6_[+5(8.14e-05)]_27 chr1:35896861-35896941 5.11e-04 [+1(1.32e-05)]_55_[+3(1.48e-05)]_9 chr3:128292890-128292970 3.53e-03 71_[+1(9.57e-05)]_1 chr14:23197617-23197697 2.98e-02 47_[+1(6.73e-05)]_25 chr1:209848511-209848591 1.52e-01 80 chr9:123446761-123446841 3.76e-01 80 chr5:136015032-136015112 7.09e-03 20_[+1(6.73e-05)]_41_[+1(4.08e-05)]_\ 3 chr14:104625328-10462540 1.73e-02 5_[+4(6.37e-05)]_67 chr21:44782944-44783024 2.80e-01 80 chr14:23025411-23025491 6.33e-03 55_[+5(1.73e-05)]_17 chr2:111920542-111920622 7.37e-01 80 chr21:46529817-46529897 5.30e-02 36_[+2(6.38e-05)]_36 chr2:75089581-75089661 6.18e-02 10_[+1(5.41e-05)]_62 chr16:69459204-69459284 8.88e-02 80 chr1:156896109-156896189 8.82e-02 80 chr3:171824904-171824984 4.78e-03 9_[+5(3.36e-05)]_49_[+3(7.46e-05)]_\ 6 chr10:11866928-11867008 8.14e-01 80 chr20:47654645-47654725 1.05e-05 9_[+5(1.73e-05)]_34_[+4(1.58e-05)]_\ 21 chr11:2959244-2959324 5.77e-01 80 chr19:13162530-13162610 1.62e-01 80 chr11:118187490-11818757 1.85e-02 6_[+3(1.48e-05)]_66 chr7:98520504-98520584 5.81e-02 70_[+1(9.57e-05)]_2 chr17:76136252-76136332 6.75e-03 27_[+3(7.46e-05)]_45 chr7:4456185-4456265 4.91e-02 80 chr6:170595922-170596002 8.18e-02 80 chr14:101909019-10190909 8.71e-01 80 chr1:181120803-181120883 2.84e-01 80 chr10:121545758-12154583 1.61e-03 36_[+2(3.19e-05)]_36 chr6:90031439-90031519 1.02e-02 80 chr8:12400653-12400733 2.06e-02 29_[+2(6.38e-05)]_43 chr4:6927380-6927460 8.42e-01 80 chr2:46361843-46361923 1.83e-01 80 chr6:151183040-151183120 1.31e-03 19_[+3(7.46e-05)]_1_[+1(5.41e-05)]_\ 44 chr20:42579023-42579103 1.99e-01 80 chr15:82333350-82333430 9.18e-01 80 chr15:66615856-66615936 3.93e-01 80 chr19:54714758-54714838 1.57e-03 1_[+2(3.19e-05)]_71 chr12:4430043-4430123 1.38e-02 55_[+4(3.24e-05)]_17 chrX:135213288-135213368 3.09e-01 80 chr1:16478023-16478103 2.26e-01 80 chr16:11706375-11706455 1.16e-02 63_[+5(6.62e-05)]_9 chr1:204370147-204370227 4.52e-02 20_[+1(2.67e-05)]_52 chr8:48911638-48911718 3.56e-01 80 chr4:113437681-113437761 1.20e-01 80 chr3:142569292-142569372 5.09e-02 34_[+2(1.59e-05)]_38 chr3:58457212-58457292 1.59e-01 80 chr1:110981672-110981752 3.61e-01 80 chr11:76092220-76092300 9.09e-02 80 chr6:101396775-101396855 7.16e-05 31_[+4(1.58e-05)]_7_[+3(1.48e-05)]_\ 26 chr21:40467210-40467290 9.13e-04 [+1(1.32e-05)]_45_[+2(9.59e-05)]_19 chr19:18854224-18854304 9.76e-02 80 chr15:89560855-89560935 7.62e-02 80 chr17:63225262-63225342 1.86e-01 80 chr17:72711380-72711460 8.86e-03 71_[+2(1.59e-05)]_1 chr1:101757242-101757322 3.26e-01 80 chr6:43359347-43359427 1.16e-02 6_[+2(6.38e-05)]_25_[+1(4.08e-05)]_\ 33 chr5:175866132-175866212 1.05e-01 80 chr8:124526623-124526703 5.39e-04 30_[+5(8.14e-05)]_42 chr5:131439429-131439509 3.25e-02 67_[+2(1.59e-05)]_5 chr17:4110432-4110512 9.49e-02 23_[+2(3.19e-05)]_16_[+2(3.19e-05)]_\ 16_[+2(3.19e-05)]_1 chrX:18372952-18373032 9.18e-01 80 chr17:32269576-32269656 3.51e-01 80 chrX:48794439-48794519 2.99e-01 80 chr8:116480005-116480085 6.94e-01 80 chr5:133023042-133023122 3.55e-04 6_[+4(1.58e-05)]_66 chr1:47845362-47845442 3.15e-01 80 chr7:135335782-135335862 7.30e-01 80 chr16:374574-374654 8.53e-03 31_[+2(4.79e-05)]_41 chr8:102049443-102049523 4.91e-01 80 chr6:159920179-159920259 4.48e-02 52_[+4(3.24e-05)]_20 chr4:4463781-4463861 1.22e-02 80 chr18:12337069-12337149 3.76e-03 8_[+3(2.87e-05)]_64 chr10:26511661-26511741 1.19e-02 11_[+1(2.67e-05)]_17_[+1(9.57e-05)]_\ 36 chr6:36793341-36793421 4.73e-01 80 chr12:132111994-13211207 2.48e-01 14_[+2(4.79e-05)]_26_[+2(4.79e-05)]_\ 24 chr6:130088430-130088510 7.66e-02 25_[+2(3.19e-05)]_47 chr21:45118567-45118647 5.27e-01 80 chr2:38779500-38779580 4.97e-03 20_[+3(7.46e-05)]_29_[+4(7.85e-05)]_\ 15 chr20:46153259-46153339 4.02e-03 22_[+1(6.73e-05)]_11_[+5(8.14e-05)]_\ 31 chrX:129259372-129259452 1.52e-03 36_[+1(2.67e-05)]_36 chr2:17775204-17775284 2.30e-01 80 chr11:10764471-10764551 7.63e-02 80 chr9:77642631-77642711 3.15e-03 80 chr9:130150787-130150867 4.60e-03 16_[+3(1.48e-05)]_56 chr3:194041745-194041825 3.82e-01 80 chr3:33109111-33109191 2.31e-01 80 chr9:136734916-136734996 3.76e-02 80 chr7:86741370-86741450 3.55e-04 6_[+4(3.24e-05)]_46_[+1(4.08e-05)]_\ 12 chr19:17828334-17828414 2.28e-02 64_[+5(3.36e-05)]_8 chr17:57635556-57635636 4.43e-02 11_[+2(9.59e-05)]_61 chr2:170972521-170972601 2.64e-02 80 chr7:108056800-108056880 1.55e-02 46_[+2(1.59e-05)]_26 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******************************************************************************** ******************************************************************************** Stopped because requested number of motifs (5) found. ******************************************************************************** CPU: c22n08.farnam.hpc.yale.internal ********************************************************************************