******************************************************************************** MEME - Motif discovery tool ******************************************************************************** MEME version 5.3.3 (Release date: Sun Feb 7 15:39:52 2021 -0800) For further information on how to interpret these results please access https://meme-suite.org/meme. To get a copy of the MEME Suite software please access https://meme-suite.org. ******************************************************************************** ******************************************************************************** REFERENCE ******************************************************************************** If you use this program in your research, please cite: Timothy L. Bailey and Charles Elkan, "Fitting a mixture model by expectation maximization to discover motifs in biopolymers", Proceedings of the Second International Conference on Intelligent Systems for Molecular Biology, pp. 28-36, AAAI Press, Menlo Park, California, 1994. ******************************************************************************** ******************************************************************************** TRAINING SET ******************************************************************************** PRIMARY SEQUENCES= ../result/final_prediction/K562/fasta/RankLinear0.6_40/GTF2F1.fasta CONTROL SEQUENCES= --none-- ALPHABET= ACGT Sequence name Weight Length Sequence name Weight Length ------------- ------ ------ ------------- ------ ------ chr22:21987029-21987109 1.0000 80 chr19:5352480-5352560 1.0000 80 chr19:41283492-41283572 1.0000 80 chr19:45430462-45430542 1.0000 80 chr11:1372887-1372967 1.0000 80 chr11:61266581-61266661 1.0000 80 chr6:32812465-32812545 1.0000 80 chr20:305999-306079 1.0000 80 chr1:181002978-181003058 1.0000 80 chr14:102176555-10217663 1.0000 80 chr14:23120275-23120355 1.0000 80 chr16:9085927-9086007 1.0000 80 chr22:21984252-21984332 1.0000 80 chr3:112360097-112360177 1.0000 80 chr6:37465154-37465234 1.0000 80 chr22:21983656-21983736 1.0000 80 chr6:26474107-26474187 1.0000 80 chr7:75947380-75947460 1.0000 80 chr6:26421533-26421613 1.0000 80 chrX:153191113-153191193 1.0000 80 chr19:50934963-50935043 1.0000 80 chr5:170814799-170814879 1.0000 80 chr22:29548881-29548961 1.0000 80 chr6:27835319-27835399 1.0000 80 chr22:21996311-21996391 1.0000 80 chr11:117997181-11799726 1.0000 80 chr2:108972762-108972842 1.0000 80 chr6:28688229-28688309 1.0000 80 chr11:122932808-12293288 1.0000 80 chr11:72433617-72433697 1.0000 80 chr1:249133168-249133248 1.0000 80 chr12:25086868-25086948 1.0000 80 chr1:207779183-207779263 1.0000 80 chr7:2913726-2913806 1.0000 80 chr10:126107449-12610752 1.0000 80 chr22:50555785-50555865 1.0000 80 chr13:108653468-10865354 1.0000 80 chr18:9014252-9014332 1.0000 80 chr19:45418391-45418471 1.0000 80 chr6:26383251-26383331 1.0000 80 chr19:56028419-56028499 1.0000 80 chr10:111971032-11197111 1.0000 80 chr6:37391702-37391782 1.0000 80 chr18:75705635-75705715 1.0000 80 chr11:120107295-12010737 1.0000 80 chr19:51182755-51182835 1.0000 80 chr1:151319779-151319859 1.0000 80 chr1:71513457-71513537 1.0000 80 chr1:46049170-46049250 1.0000 80 chr2:158115212-158115292 1.0000 80 chr1:149215268-149215348 1.0000 80 chr19:50093561-50093641 1.0000 80 chr11:129939747-12993982 1.0000 80 chr19:2042303-2042383 1.0000 80 chr11:6640668-6640748 1.0000 80 chr3:129118796-129118876 1.0000 80 chr5:16528551-16528631 1.0000 80 chr12:6643666-6643746 1.0000 80 chr8:101734296-101734376 1.0000 80 chr11:121097253-12109733 1.0000 80 chr3:25706478-25706558 1.0000 80 chr2:30884150-30884230 1.0000 80 chr17:79008923-79009003 1.0000 80 chr19:49078078-49078158 1.0000 80 chr17:17255671-17255751 1.0000 80 chrX:41193377-41193457 1.0000 80 chr6:29617898-29617978 1.0000 80 chr3:24537170-24537250 1.0000 80 chr5:140699862-140699942 1.0000 80 chr9:130186373-130186453 1.0000 80 chr22:30841048-30841128 1.0000 80 chr6:30457154-30457234 1.0000 80 chr1:20204943-20205023 1.0000 80 chr6:28188416-28188496 1.0000 80 chr5:43040529-43040609 1.0000 80 chr9:123639837-123639917 1.0000 80 chr15:93426014-93426094 1.0000 80 chr6:31430822-31430902 1.0000 80 chr10:23344715-23344795 1.0000 80 chr11:65222706-65222786 1.0000 80 chr8:125827944-125828024 1.0000 80 chr5:137801117-137801197 1.0000 80 chr2:30454360-30454440 1.0000 80 chr21:15918600-15918680 1.0000 80 chr1:33430381-33430461 1.0000 80 chr6:3118551-3118631 1.0000 80 chr20:52369809-52369889 1.0000 80 chr6:15211390-15211470 1.0000 80 chr3:13044284-13044364 1.0000 80 chr11:64937652-64937732 1.0000 80 chr11:2398502-2398582 1.0000 80 chr6:28677830-28677910 1.0000 80 chr19:51111386-51111466 1.0000 80 chr14:102553348-10255342 1.0000 80 chr6:26033841-26033921 1.0000 80 chr11:62495376-62495456 1.0000 80 chr6:27775706-27775786 1.0000 80 chr11:62619293-62619373 1.0000 80 chr6:27833050-27833130 1.0000 80 chr10:70320051-70320131 1.0000 80 chr14:20937533-20937613 1.0000 80 chr19:48948734-48948814 1.0000 80 chr17:38136745-38136825 1.0000 80 chr17:41393221-41393301 1.0000 80 chr12:108513212-10851329 1.0000 80 chr22:42196640-42196720 1.0000 80 chr6:42952197-42952277 1.0000 80 chr10:14880035-14880115 1.0000 80 chr1:100828488-100828568 1.0000 80 chr12:50505529-50505609 1.0000 80 chr1:32801811-32801891 1.0000 80 chr19:36103582-36103662 1.0000 80 chr9:113018755-113018835 1.0000 80 chr8:37963422-37963502 1.0000 80 chr5:173615545-173615625 1.0000 80 chr1:149858224-149858304 1.0000 80 chr1:76251907-76251987 1.0000 80 chr6:26365320-26365400 1.0000 80 chr6:27100537-27100617 1.0000 80 chr6:30843363-30843443 1.0000 80 chr20:26189279-26189359 1.0000 80 chr21:36261027-36261107 1.0000 80 chr3:128206750-128206830 1.0000 80 chr3:150320997-150321077 1.0000 80 chr6:26251823-26251903 1.0000 80 chr6:32407524-32407604 1.0000 80 chr19:5309003-5309083 1.0000 80 chr4:38324978-38325058 1.0000 80 chr19:1269289-1269369 1.0000 80 chr17:20771805-20771885 1.0000 80 chr9:106856225-106856305 1.0000 80 chr1:52796048-52796128 1.0000 80 chr10:3214935-3215015 1.0000 80 chr17:21515824-21515904 1.0000 80 chr14:51135228-51135308 1.0000 80 chrX:118602343-118602423 1.0000 80 chr6:134495966-134496046 1.0000 80 chr20:47662803-47662883 1.0000 80 chr3:129035089-129035169 1.0000 80 chr16:27210385-27210465 1.0000 80 chr19:9676715-9676795 1.0000 80 chr11:129872766-12987284 1.0000 80 chr5:162864554-162864634 1.0000 80 chr7:104655506-104655586 1.0000 80 chr6:31865537-31865617 1.0000 80 chr9:123638283-123638363 1.0000 80 chr2:232573158-232573238 1.0000 80 chr1:210547595-210547675 1.0000 80 chr6:26235185-26235265 1.0000 80 chr7:99277242-99277322 1.0000 80 chr3:151986716-151986796 1.0000 80 chr21:33104329-33104409 1.0000 80 chr17:45253851-45253931 1.0000 80 chr19:59055791-59055871 1.0000 80 chr1:118148646-118148726 1.0000 80 chr22:22335089-22335169 1.0000 80 chr3:70048857-70048937 1.0000 80 chr21:33031970-33032050 1.0000 80 chr1:200610204-200610284 1.0000 80 chr16:8159625-8159705 1.0000 80 chr2:61763887-61763967 1.0000 80 chr11:5526828-5526908 1.0000 80 chr22:23470757-23470837 1.0000 80 chr16:57717033-57717113 1.0000 80 chr1:149224305-149224385 1.0000 80 chr1:149858429-149858509 1.0000 80 chr15:69745103-69745183 1.0000 80 chr17:75315512-75315592 1.0000 80 chr5:27217794-27217874 1.0000 80 chr5:90676860-90676940 1.0000 80 chr10:14227409-14227489 1.0000 80 chr5:78884620-78884700 1.0000 80 chr17:56744009-56744089 1.0000 80 chr22:22001192-22001272 1.0000 80 chr22:21979301-21979381 1.0000 80 chr1:12717576-12717656 1.0000 80 chr15:45003634-45003714 1.0000 80 chr16:69760396-69760476 1.0000 80 chr1:160696114-160696194 1.0000 80 chr2:183903681-183903761 1.0000 80 chr17:42147520-42147600 1.0000 80 chr21:46493706-46493786 1.0000 80 chrX:123096959-123097039 1.0000 80 chr5:56205850-56205930 1.0000 80 chr6:26158086-26158166 1.0000 80 chr22:43411346-43411426 1.0000 80 chr3:100120388-100120468 1.0000 80 chr14:62162194-62162274 1.0000 80 chr16:14724214-14724294 1.0000 80 chrX:12993222-12993302 1.0000 80 chr4:127877188-127877268 1.0000 80 chr5:179050649-179050729 1.0000 80 chr6:37137939-37138019 1.0000 80 chr4:111115149-111115229 1.0000 80 chr22:23596232-23596312 1.0000 80 chr2:152118451-152118531 1.0000 80 chr16:2955361-2955441 1.0000 80 chr19:2476065-2476145 1.0000 80 chr22:22006432-22006512 1.0000 80 chr6:31795481-31795561 1.0000 80 chr11:62341312-62341392 1.0000 80 chr13:52027155-52027235 1.0000 80 chr2:9771340-9771420 1.0000 80 chr15:75052951-75053031 1.0000 80 chr15:64673607-64673687 1.0000 80 chr17:62502372-62502452 1.0000 80 chr19:2051210-2051290 1.0000 80 chr6:26458056-26458136 1.0000 80 chr13:27825607-27825687 1.0000 80 chr6:26158294-26158374 1.0000 80 chr20:32891110-32891190 1.0000 80 chr17:79479782-79479862 1.0000 80 chr4:681236-681316 1.0000 80 chr22:23536036-23536116 1.0000 80 chr1:59249672-59249752 1.0000 80 chr9:131940507-131940587 1.0000 80 chrX:48380182-48380262 1.0000 80 chr15:88120126-88120206 1.0000 80 chr6:42713758-42713838 1.0000 80 chr1:100503635-100503715 1.0000 80 chr10:11936649-11936729 1.0000 80 chr5:90679094-90679174 1.0000 80 chr6:31789952-31790032 1.0000 80 chr11:64646062-64646142 1.0000 80 chr1:40042408-40042488 1.0000 80 chr22:22133081-22133161 1.0000 80 chr22:19710297-19710377 1.0000 80 chr1:147735700-147735780 1.0000 80 chr19:34895151-34895231 1.0000 80 chr22:22337168-22337248 1.0000 80 chr6:26124353-26124433 1.0000 80 chr19:5791310-5791390 1.0000 80 chr6:31625965-31626045 1.0000 80 chr5:149790244-149790324 1.0000 80 chr1:23885965-23886045 1.0000 80 chr10:16933851-16933931 1.0000 80 chr17:17739672-17739752 1.0000 80 chr2:145116664-145116744 1.0000 80 chr17:33894874-33894954 1.0000 80 chr19:6536225-6536305 1.0000 80 chr6:42946902-42946982 1.0000 80 chr14:23426284-23426364 1.0000 80 chr8:97247721-97247801 1.0000 80 chr12:49525137-49525217 1.0000 80 chr11:93474613-93474693 1.0000 80 chr14:20811555-20811635 1.0000 80 chr4:119199893-119199973 1.0000 80 chr15:91412988-91413068 1.0000 80 chrX:129116577-129116657 1.0000 80 chr1:68150851-68150931 1.0000 80 ******************************************************************************** ******************************************************************************** COMMAND LINE SUMMARY ******************************************************************************** This information can also be useful in the event you wish to report a problem with the MEME software. command: meme -oc ../result/final_prediction/K562/inference_raw/MEME/RankLinear0.6_40_GTF2F1/ -dna -nmotifs 5 -w 8 -maxsize 250000 -nostatus ../result/final_prediction/K562/fasta/RankLinear0.6_40/GTF2F1.fasta model: mod= zoops nmotifs= 5 evt= inf objective function: em= E-value of product of p-values starts= E-value of product of p-values strands: + width: minw= 8 maxw= 8 nsites: minsites= 2 maxsites= 250 wnsites= 0.8 theta: spmap= uni spfuzz= 0.5 em: prior= dirichlet b= 0.01 maxiter= 50 distance= 1e-05 trim: wg= 11 ws= 1 endgaps= yes data: n= 20000 N= 250 sample: seed= 0 hsfrac= 0 searchsize= 20000 norand= no csites= 1000 Letter frequencies in dataset: A 0.217 C 0.282 G 0.28 T 0.221 Background letter frequencies (from file dataset with add-one prior applied): A 0.218 C 0.282 G 0.28 T 0.221 Background model order: 0 ******************************************************************************** ******************************************************************************** MOTIF YTWTAWAR MEME-1 width = 8 sites = 42 llr = 349 E-value = 2.2e-009 ******************************************************************************** -------------------------------------------------------------------------------- Motif YTWTAWAR MEME-1 Description -------------------------------------------------------------------------------- Simplified A ::7:94a5 pos.-specific C 5::::::: probability G :::::::3 matrix T 4a3a16:2 bits 2.2 * 2.0 * * * 1.8 * ** * 1.5 * ** * Relative 1.3 ****** Entropy 1.1 ****** (12.0 bits) 0.9 ******* 0.7 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel CTATATAA consensus T T A G sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YTWTAWAR MEME-1 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr19:5791310-5791390 11 1.23e-05 GCCTCAGGTC CTATATAA ACTAGAGCCT chrX:118602343-118602423 34 1.23e-05 CCGGCTCCCC CTATATAA ATCGGCCATT chr6:27775706-27775786 27 1.23e-05 TCTCCTCTTT TTATATAA TAGTTTATGC chr11:64937652-64937732 22 1.23e-05 CGCCCTCAGG CTATATAA GCGCACTCGC chr6:27835319-27835399 71 1.23e-05 GGCCCCGGGC TTATATAA GC chr6:26124353-26124433 15 2.44e-05 CAGGAACTAC CTATAAAA GCGGCCATGT chr6:31795481-31795561 4 2.44e-05 GAC TTATAAAA GCCGAGGGGC chr19:2476065-2476145 28 2.44e-05 ATGTTCAAGT CTATAAAA GTCGGTGCCG chr5:27217794-27217874 1 2.44e-05 . ctataaaa acccccgagg chr16:27210385-27210465 14 2.44e-05 tcaaactgga ctataaaa tttgcgcatt chr6:134495966-134496046 59 2.44e-05 GCGCTCGGCC TTATAAAA AAGGCACCGC chr4:38324978-38325058 32 3.68e-05 GATGCATGTT TTTTATAA GCATTCCCAA chr1:149858224-149858304 32 3.68e-05 GGCCTGATTC TTTTATAA CCACCTTATG chr9:113018755-113018835 56 3.68e-05 TGCTCTCTCC CTTTATAA ACTGGCACGC chr1:71513457-71513537 63 3.68e-05 GCCGAGTCCC CTTTATAA GGCCGAGGGG chr18:75705635-75705715 68 3.68e-05 aaactcccgt ttttataa ccatc chr2:108972762-108972842 6 3.68e-05 gtgcc ctttataa gaatcaacaa chr6:26235185-26235265 56 5.25e-05 GGCTGAGGGT TTATATAG AGAGACGCTG chr14:102553348-10255342 57 5.25e-05 CGCGCCTGCC TTATATAG CGACGGGCCC chr1:32801811-32801891 45 6.50e-05 GCCGAGCTGC CTATATAT AAGCGCCCGG chr5:170814799-170814879 26 6.50e-05 TCTTCAGGGT CTATATAT AAGCGCGGGG chr17:45253851-45253931 37 7.72e-05 CTGGAAGAAG TTTTAAAA GGCTCCTTag chr1:149858429-149858509 9 9.28e-05 AGGAAAGC TTATAAAG GCTTTCCTCT chr21:33031970-33032050 2 9.28e-05 C CTATAAAG TAGTCGCGGA chr1:33430381-33430461 57 9.28e-05 GACGAAGTGA TTATAAAG CCTCCGCCCC chr11:64646062-64646142 56 1.21e-04 GCGGAGCGGC CTTTATAG GGTCGGTCCC chr6:26158294-26158374 26 1.21e-04 AATACCGCAT CTATAAAT GAACAGGGCC chr19:2051210-2051290 56 1.21e-04 ccgccgccac cTTTATAG GCCCGGACCT chr17:62502372-62502452 59 1.21e-04 CGGCAGCCGC TTTTATAG TCTGGACCGC chr3:129035089-129035169 65 1.21e-04 TCTCTCGGCT TTTTATAG CTTCATGG chr6:30843363-30843443 10 1.21e-04 caagctgga ctataaat tcggctcatc chr1:100828488-100828568 64 1.21e-04 ccgcaacagg ttttatag tctggcttg chr2:30454360-30454440 8 1.21e-04 CCCGCCC CTATAAAT ACGGCTTCCC chr9:130186373-130186453 62 1.49e-04 TTCTGGTGGA CTTTAAAG ACGTGTGCAA chr17:79479782-79479862 67 1.74e-04 TCCCCCGCCG TTATTTAA GCGGAA chr20:32891110-32891190 73 1.74e-04 GCGCCGACGC CTTTAAAT chr22:43411346-43411426 12 1.74e-04 CGGGGAGTGC CTATTTAA TGGGCTGCGA chr9:131940507-131940587 55 2.20e-04 CCGGCCCCAG CTATTTAG CCGGGTGCCC chr7:99277242-99277322 25 2.38e-04 GGAGAAATGC TTATTTAT TCATTCATAG chr5:78884620-78884700 66 3.03e-04 ctaaccagcc taatataa gcccggt chr2:232573158-232573238 47 3.03e-04 GCCCACTAAT CTATATTA AAGCTTCTGG chr5:16528551-16528631 17 3.37e-04 CTTGTGATGG ATATATAT TCCACCTGCC -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YTWTAWAR MEME-1 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr19:5791310-5791390 1.2e-05 10_[+1]_62 chrX:118602343-118602423 1.2e-05 33_[+1]_39 chr6:27775706-27775786 1.2e-05 26_[+1]_46 chr11:64937652-64937732 1.2e-05 21_[+1]_51 chr6:27835319-27835399 1.2e-05 70_[+1]_2 chr6:26124353-26124433 2.4e-05 14_[+1]_58 chr6:31795481-31795561 2.4e-05 3_[+1]_69 chr19:2476065-2476145 2.4e-05 27_[+1]_45 chr5:27217794-27217874 2.4e-05 [+1]_72 chr16:27210385-27210465 2.4e-05 13_[+1]_59 chr6:134495966-134496046 2.4e-05 58_[+1]_14 chr4:38324978-38325058 3.7e-05 31_[+1]_41 chr1:149858224-149858304 3.7e-05 31_[+1]_41 chr9:113018755-113018835 3.7e-05 55_[+1]_17 chr1:71513457-71513537 3.7e-05 62_[+1]_10 chr18:75705635-75705715 3.7e-05 67_[+1]_5 chr2:108972762-108972842 3.7e-05 5_[+1]_67 chr6:26235185-26235265 5.3e-05 55_[+1]_17 chr14:102553348-10255342 5.3e-05 56_[+1]_16 chr1:32801811-32801891 6.5e-05 44_[+1]_28 chr5:170814799-170814879 6.5e-05 25_[+1]_47 chr17:45253851-45253931 7.7e-05 36_[+1]_36 chr1:149858429-149858509 9.3e-05 8_[+1]_64 chr21:33031970-33032050 9.3e-05 1_[+1]_71 chr1:33430381-33430461 9.3e-05 56_[+1]_16 chr11:64646062-64646142 0.00012 55_[+1]_17 chr6:26158294-26158374 0.00012 25_[+1]_47 chr19:2051210-2051290 0.00012 55_[+1]_17 chr17:62502372-62502452 0.00012 58_[+1]_14 chr3:129035089-129035169 0.00012 64_[+1]_8 chr6:30843363-30843443 0.00012 9_[+1]_63 chr1:100828488-100828568 0.00012 63_[+1]_9 chr2:30454360-30454440 0.00012 7_[+1]_65 chr9:130186373-130186453 0.00015 61_[+1]_11 chr17:79479782-79479862 0.00017 66_[+1]_6 chr20:32891110-32891190 0.00017 72_[+1] chr22:43411346-43411426 0.00017 11_[+1]_61 chr9:131940507-131940587 0.00022 54_[+1]_18 chr7:99277242-99277322 0.00024 24_[+1]_48 chr5:78884620-78884700 0.0003 65_[+1]_7 chr2:232573158-232573238 0.0003 46_[+1]_26 chr5:16528551-16528631 0.00034 16_[+1]_56 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YTWTAWAR MEME-1 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF YTWTAWAR width=8 seqs=42 chr19:5791310-5791390 ( 11) CTATATAA 1 chrX:118602343-118602423 ( 34) CTATATAA 1 chr6:27775706-27775786 ( 27) TTATATAA 1 chr11:64937652-64937732 ( 22) CTATATAA 1 chr6:27835319-27835399 ( 71) TTATATAA 1 chr6:26124353-26124433 ( 15) CTATAAAA 1 chr6:31795481-31795561 ( 4) TTATAAAA 1 chr19:2476065-2476145 ( 28) CTATAAAA 1 chr5:27217794-27217874 ( 1) CTATAAAA 1 chr16:27210385-27210465 ( 14) CTATAAAA 1 chr6:134495966-134496046 ( 59) TTATAAAA 1 chr4:38324978-38325058 ( 32) TTTTATAA 1 chr1:149858224-149858304 ( 32) TTTTATAA 1 chr9:113018755-113018835 ( 56) CTTTATAA 1 chr1:71513457-71513537 ( 63) CTTTATAA 1 chr18:75705635-75705715 ( 68) TTTTATAA 1 chr2:108972762-108972842 ( 6) CTTTATAA 1 chr6:26235185-26235265 ( 56) TTATATAG 1 chr14:102553348-10255342 ( 57) TTATATAG 1 chr1:32801811-32801891 ( 45) CTATATAT 1 chr5:170814799-170814879 ( 26) CTATATAT 1 chr17:45253851-45253931 ( 37) TTTTAAAA 1 chr1:149858429-149858509 ( 9) TTATAAAG 1 chr21:33031970-33032050 ( 2) CTATAAAG 1 chr1:33430381-33430461 ( 57) TTATAAAG 1 chr11:64646062-64646142 ( 56) CTTTATAG 1 chr6:26158294-26158374 ( 26) CTATAAAT 1 chr19:2051210-2051290 ( 56) CTTTATAG 1 chr17:62502372-62502452 ( 59) TTTTATAG 1 chr3:129035089-129035169 ( 65) TTTTATAG 1 chr6:30843363-30843443 ( 10) CTATAAAT 1 chr1:100828488-100828568 ( 64) TTTTATAG 1 chr2:30454360-30454440 ( 8) CTATAAAT 1 chr9:130186373-130186453 ( 62) CTTTAAAG 1 chr17:79479782-79479862 ( 67) TTATTTAA 1 chr20:32891110-32891190 ( 73) CTTTAAAT 1 chr22:43411346-43411426 ( 12) CTATTTAA 1 chr9:131940507-131940587 ( 55) CTATTTAG 1 chr7:99277242-99277322 ( 25) TTATTTAT 1 chr5:78884620-78884700 ( 66) TAATATAA 1 chr2:232573158-232573238 ( 47) CTATATTA 1 chr5:16528551-16528631 ( 17) ATATATAT 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YTWTAWAR MEME-1 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 8.25365 E= 2.2e-009 -319 96 -1204 96 -319 -1204 -1204 214 162 -1204 -1204 59 -1204 -1204 -1204 218 206 -1204 -1204 -121 72 -1204 -1204 154 217 -1204 -1204 -321 127 -1204 3 -21 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YTWTAWAR MEME-1 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 42 E= 2.2e-009 0.023810 0.547619 0.000000 0.428571 0.023810 0.000000 0.000000 0.976190 0.666667 0.000000 0.000000 0.333333 0.000000 0.000000 0.000000 1.000000 0.904762 0.000000 0.000000 0.095238 0.357143 0.000000 0.000000 0.642857 0.976190 0.000000 0.000000 0.023810 0.523810 0.000000 0.285714 0.190476 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YTWTAWAR MEME-1 regular expression -------------------------------------------------------------------------------- [CT]T[AT]TA[TA]A[AG] -------------------------------------------------------------------------------- Time 5.20 secs. ******************************************************************************** ******************************************************************************** MOTIF ATTGGCTG MEME-2 width = 8 sites = 11 llr = 118 E-value = 2.6e+000 ******************************************************************************** -------------------------------------------------------------------------------- Motif ATTGGCTG MEME-2 Description -------------------------------------------------------------------------------- Simplified A a::::::2 pos.-specific C :::::a:: probability G :::aa::8 matrix T :aa:::a: bits 2.2 *** * 2.0 *** * 1.8 ******* 1.5 ******* Relative 1.3 ******** Entropy 1.1 ******** (15.5 bits) 0.9 ******** 0.7 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel ATTGGCTG consensus sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ATTGGCTG MEME-2 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr6:26458056-26458136 44 1.46e-05 GTTCGACACC ATTGGCTG GTTCACTCAC chr15:45003634-45003714 32 1.46e-05 CCTTGTCCTG ATTGGCTG GGCACGCGTT chr12:50505529-50505609 68 1.46e-05 TAGGCTGAGG ATTGGCTG ACTCT chr19:51111386-51111466 45 1.46e-05 TCCCTGCCTT ATTGGCTG CCTTCGACCA chr19:45418391-45418471 50 1.46e-05 CACCTCTGGG ATTGGCTG TCCTGCTTCG chr1:249133168-249133248 64 1.46e-05 GCGCCCCAGG ATTGGCTG CGCTGCTGT chr11:72433617-72433697 51 1.46e-05 AAGACCAGGG ATTGGCTG GACTGCAGGG chr6:26421533-26421613 44 1.46e-05 GCTCGACACC ATTGGCTG GTTCACTCAC chr19:45430462-45430542 63 1.46e-05 CACCTCTGGG ATTGGCTG TCCTCCTTTT chr4:111115149-111115229 7 2.59e-05 ATCATC ATTGGCTA GACAATTACA chr6:26033841-26033921 68 2.59e-05 GAATTCTCCC ATTGGCTA ATGTC -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ATTGGCTG MEME-2 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr6:26458056-26458136 1.5e-05 43_[+2]_29 chr15:45003634-45003714 1.5e-05 31_[+2]_41 chr12:50505529-50505609 1.5e-05 67_[+2]_5 chr19:51111386-51111466 1.5e-05 44_[+2]_28 chr19:45418391-45418471 1.5e-05 49_[+2]_23 chr1:249133168-249133248 1.5e-05 63_[+2]_9 chr11:72433617-72433697 1.5e-05 50_[+2]_22 chr6:26421533-26421613 1.5e-05 43_[+2]_29 chr19:45430462-45430542 1.5e-05 62_[+2]_10 chr4:111115149-111115229 2.6e-05 6_[+2]_66 chr6:26033841-26033921 2.6e-05 67_[+2]_5 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ATTGGCTG MEME-2 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF ATTGGCTG width=8 seqs=11 chr6:26458056-26458136 ( 44) ATTGGCTG 1 chr15:45003634-45003714 ( 32) ATTGGCTG 1 chr12:50505529-50505609 ( 68) ATTGGCTG 1 chr19:51111386-51111466 ( 45) ATTGGCTG 1 chr19:45418391-45418471 ( 50) ATTGGCTG 1 chr1:249133168-249133248 ( 64) ATTGGCTG 1 chr11:72433617-72433697 ( 51) ATTGGCTG 1 chr6:26421533-26421613 ( 44) ATTGGCTG 1 chr19:45430462-45430542 ( 63) ATTGGCTG 1 chr4:111115149-111115229 ( 7) ATTGGCTA 1 chr6:26033841-26033921 ( 68) ATTGGCTA 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ATTGGCTG MEME-2 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 11.0506 E= 2.6e+000 220 -1010 -1010 -1010 -1010 -1010 -1010 218 -1010 -1010 -1010 218 -1010 -1010 184 -1010 -1010 -1010 184 -1010 -1010 183 -1010 -1010 -1010 -1010 -1010 218 -26 -1010 155 -1010 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ATTGGCTG MEME-2 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 11 E= 2.6e+000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.181818 0.000000 0.818182 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ATTGGCTG MEME-2 regular expression -------------------------------------------------------------------------------- ATTGGCTG -------------------------------------------------------------------------------- Time 8.98 secs. ******************************************************************************** ******************************************************************************** MOTIF CCYRGCAA MEME-3 width = 8 sites = 24 llr = 215 E-value = 1.3e+000 ******************************************************************************** -------------------------------------------------------------------------------- Motif CCYRGCAA MEME-3 Description -------------------------------------------------------------------------------- Simplified A :::6::aa pos.-specific C aa5::8:: probability G :::3a::: matrix T ::51:2:: bits 2.2 ** 2.0 ** 1.8 ** * ** 1.5 ** * ** Relative 1.3 ** **** Entropy 1.1 *** **** (12.9 bits) 0.9 *** **** 0.7 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel CCTAGCAA consensus CG sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCYRGCAA MEME-3 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr6:32407524-32407604 32 1.44e-05 GAACCCTTCC CCTAGCAA CAGATGCGTC chr7:75947380-75947460 56 1.44e-05 GGACCCAGGC CCTAGCAA CAGTCCGACC chr1:181002978-181003058 40 1.44e-05 TTTTTTTTAA CCTAGCAA CTGATGACAC chr6:26458056-26458136 11 3.27e-05 GTGTATTCTA CCCAGCAA CTGCTGAGAA chr17:56744009-56744089 66 3.27e-05 CTTGCGTGAC CCCAGCAA TCCCCGG chr6:26365320-26365400 44 3.27e-05 GTGGTTTCTG CCCAGCAA CTGATGAGAA chr11:62495376-62495456 3 3.27e-05 TA CCCAGCAA CAGAGGCCCT chr1:249133168-249133248 24 3.27e-05 AGAAAGTTTG CCCAGCAA CTTGTGACGC chr6:26474107-26474187 27 3.27e-05 GTGGCTTCTG CCCAGCAA CTGATGAGAA chr20:305999-306079 30 3.27e-05 GGCTTCTCTG CCCAGCAA CGGGTGACGC chr6:32812465-32812545 41 3.27e-05 GCCTCATCTA CCCAGCAA CTGTCGACGT chr19:6536225-6536305 23 5.12e-05 GAATAAGACC cctggcaa caggtgattc chr11:129872766-12987284 5 5.12e-05 TCTG CCTGGCAA CCTGATCTCG chr11:72433617-72433697 14 5.12e-05 CAAGTTCTGC CCTGGCAA CAAGTGATCA chr19:50934963-50935043 44 5.12e-05 TGGCAGTCTG CCTGGCAA CCCGTGACAT chr19:36103582-36103662 13 8.60e-05 CCGCTGTCTG CCCGGCAA CCGATGACGT chr17:38136745-38136825 4 8.60e-05 CCG CCCGGCAA CTCGTGACGT chr11:6640668-6640748 37 8.60e-05 TACCCCTCTG CCTAGTAA CTAGTGACGG chr6:26421533-26421613 11 8.60e-05 GTGTATTCTA CCTAGTAA CTGCTGAGAA chr19:45430462-45430542 24 8.60e-05 CCAGGAGAGC CCTAGTAA CCGATGACGT chr12:108513212-10851329 50 1.01e-04 tcagacattt ccttgcaa actgaaagtg chr5:43040529-43040609 10 1.01e-04 CCCTAACCA CCTTGCAA ACGAGAAACT chr15:88120126-88120206 59 1.34e-04 catgcgattg ccctgcaa caccttggaa chr19:49078078-49078158 32 1.48e-04 ACTAAATTTG CCTGGTAA CCGATGACAT -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCYRGCAA MEME-3 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr6:32407524-32407604 1.4e-05 31_[+3]_41 chr7:75947380-75947460 1.4e-05 55_[+3]_17 chr1:181002978-181003058 1.4e-05 39_[+3]_33 chr6:26458056-26458136 3.3e-05 10_[+3]_62 chr17:56744009-56744089 3.3e-05 65_[+3]_7 chr6:26365320-26365400 3.3e-05 43_[+3]_29 chr11:62495376-62495456 3.3e-05 2_[+3]_70 chr1:249133168-249133248 3.3e-05 23_[+3]_49 chr6:26474107-26474187 3.3e-05 26_[+3]_46 chr20:305999-306079 3.3e-05 29_[+3]_43 chr6:32812465-32812545 3.3e-05 40_[+3]_32 chr19:6536225-6536305 5.1e-05 22_[+3]_50 chr11:129872766-12987284 5.1e-05 4_[+3]_68 chr11:72433617-72433697 5.1e-05 13_[+3]_59 chr19:50934963-50935043 5.1e-05 43_[+3]_29 chr19:36103582-36103662 8.6e-05 12_[+3]_60 chr17:38136745-38136825 8.6e-05 3_[+3]_69 chr11:6640668-6640748 8.6e-05 36_[+3]_36 chr6:26421533-26421613 8.6e-05 10_[+3]_62 chr19:45430462-45430542 8.6e-05 23_[+3]_49 chr12:108513212-10851329 0.0001 49_[+3]_23 chr5:43040529-43040609 0.0001 9_[+3]_63 chr15:88120126-88120206 0.00013 58_[+3]_14 chr19:49078078-49078158 0.00015 31_[+3]_41 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCYRGCAA MEME-3 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF CCYRGCAA width=8 seqs=24 chr6:32407524-32407604 ( 32) CCTAGCAA 1 chr7:75947380-75947460 ( 56) CCTAGCAA 1 chr1:181002978-181003058 ( 40) CCTAGCAA 1 chr6:26458056-26458136 ( 11) CCCAGCAA 1 chr17:56744009-56744089 ( 66) CCCAGCAA 1 chr6:26365320-26365400 ( 44) CCCAGCAA 1 chr11:62495376-62495456 ( 3) CCCAGCAA 1 chr1:249133168-249133248 ( 24) CCCAGCAA 1 chr6:26474107-26474187 ( 27) CCCAGCAA 1 chr20:305999-306079 ( 30) CCCAGCAA 1 chr6:32812465-32812545 ( 41) CCCAGCAA 1 chr19:6536225-6536305 ( 23) CCTGGCAA 1 chr11:129872766-12987284 ( 5) CCTGGCAA 1 chr11:72433617-72433697 ( 14) CCTGGCAA 1 chr19:50934963-50935043 ( 44) CCTGGCAA 1 chr19:36103582-36103662 ( 13) CCCGGCAA 1 chr17:38136745-38136825 ( 4) CCCGGCAA 1 chr11:6640668-6640748 ( 37) CCTAGTAA 1 chr6:26421533-26421613 ( 11) CCTAGTAA 1 chr19:45430462-45430542 ( 24) CCTAGTAA 1 chr12:108513212-10851329 ( 50) CCTTGCAA 1 chr5:43040529-43040609 ( 10) CCTTGCAA 1 chr15:88120126-88120206 ( 59) CCCTGCAA 1 chr19:49078078-49078158 ( 32) CCTGGTAA 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCYRGCAA MEME-3 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 10.6693 E= 1.3e+000 -1123 183 -1123 -1123 -1123 183 -1123 -1123 -1123 70 -1123 129 142 -1123 6 -82 -1123 -1123 184 -1123 -1123 156 -1123 -41 220 -1123 -1123 -1123 220 -1123 -1123 -1123 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCYRGCAA MEME-3 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 24 E= 1.3e+000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.458333 0.000000 0.541667 0.583333 0.000000 0.291667 0.125000 0.000000 0.000000 1.000000 0.000000 0.000000 0.833333 0.000000 0.166667 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCYRGCAA MEME-3 regular expression -------------------------------------------------------------------------------- CC[TC][AG]GCAA -------------------------------------------------------------------------------- Time 12.77 secs. ******************************************************************************** ******************************************************************************** MOTIF RGCCAATC MEME-4 width = 8 sites = 11 llr = 114 E-value = 1.5e+002 ******************************************************************************** -------------------------------------------------------------------------------- Motif RGCCAATC MEME-4 Description -------------------------------------------------------------------------------- Simplified A 5:::aa:: pos.-specific C ::aa:::a probability G 5a:::::: matrix T ::::::a: bits 2.2 *** 2.0 *** 1.8 ******* 1.5 ******* Relative 1.3 ******* Entropy 1.1 ******** (14.9 bits) 0.9 ******** 0.7 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel AGCCAATC consensus G sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif RGCCAATC MEME-4 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr3:128206750-128206830 63 1.44e-05 AGCCCAAGCC AGCCAATC AACGCCGCGC chr6:30457154-30457234 73 1.44e-05 TTTCTAGAGA AGCCAATC chr1:46049170-46049250 17 1.44e-05 TTTCAGCTGT AGCCAATC CTAGAACAAA chr19:51182755-51182835 39 1.44e-05 CAGAAGGGAC AGCCAATC AGAGTGCGCA chr10:111971032-11197111 15 1.44e-05 TGCGTCGTTC AGCCAATC GGCAGCTCCA chr6:26474107-26474187 57 1.44e-05 GGTACCTCTG AGCCAATC AAAACACGAA chr6:26458056-26458136 66 3.28e-05 ACTCACACCC GGCCAATC CTGGGCT chr21:36261027-36261107 52 3.28e-05 GGCGGCCGGC GGCCAATC ACAGGCCTTT chr3:25706478-25706558 19 3.28e-05 ACAGCCTCTC GGCCAATC CCAAAATTCC chr6:26383251-26383331 47 3.28e-05 AGCCTCACTC GGCCAATC CTGGGCTCTA chr6:26421533-26421613 66 3.28e-05 ACTCACACCC GGCCAATC CTGGACT -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif RGCCAATC MEME-4 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr3:128206750-128206830 1.4e-05 62_[+4]_10 chr6:30457154-30457234 1.4e-05 72_[+4] chr1:46049170-46049250 1.4e-05 16_[+4]_56 chr19:51182755-51182835 1.4e-05 38_[+4]_34 chr10:111971032-11197111 1.4e-05 14_[+4]_58 chr6:26474107-26474187 1.4e-05 56_[+4]_16 chr6:26458056-26458136 3.3e-05 65_[+4]_7 chr21:36261027-36261107 3.3e-05 51_[+4]_21 chr3:25706478-25706558 3.3e-05 18_[+4]_54 chr6:26383251-26383331 3.3e-05 46_[+4]_26 chr6:26421533-26421613 3.3e-05 65_[+4]_7 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif RGCCAATC MEME-4 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF RGCCAATC width=8 seqs=11 chr3:128206750-128206830 ( 63) AGCCAATC 1 chr6:30457154-30457234 ( 73) AGCCAATC 1 chr1:46049170-46049250 ( 17) AGCCAATC 1 chr19:51182755-51182835 ( 39) AGCCAATC 1 chr10:111971032-11197111 ( 15) AGCCAATC 1 chr6:26474107-26474187 ( 57) AGCCAATC 1 chr6:26458056-26458136 ( 66) GGCCAATC 1 chr21:36261027-36261107 ( 52) GGCCAATC 1 chr3:25706478-25706558 ( 19) GGCCAATC 1 chr6:26383251-26383331 ( 47) GGCCAATC 1 chr6:26421533-26421613 ( 66) GGCCAATC 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif RGCCAATC MEME-4 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 10.2475 E= 1.5e+002 133 -1010 70 -1010 -1010 -1010 184 -1010 -1010 183 -1010 -1010 -1010 183 -1010 -1010 220 -1010 -1010 -1010 220 -1010 -1010 -1010 -1010 -1010 -1010 218 -1010 183 -1010 -1010 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif RGCCAATC MEME-4 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 11 E= 1.5e+002 0.545455 0.000000 0.454545 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif RGCCAATC MEME-4 regular expression -------------------------------------------------------------------------------- [AG]GCCAATC -------------------------------------------------------------------------------- Time 16.48 secs. ******************************************************************************** ******************************************************************************** MOTIF KGAGAAAW MEME-5 width = 8 sites = 11 llr = 112 E-value = 4.0e+002 ******************************************************************************** -------------------------------------------------------------------------------- Motif KGAGAAAW MEME-5 Description -------------------------------------------------------------------------------- Simplified A ::a:aaa4 pos.-specific C :::::::: probability G 5a:a:::: matrix T 5::::::6 bits 2.2 * *** 2.0 * *** 1.8 ****** 1.5 ****** Relative 1.3 ******* Entropy 1.1 ******** (14.7 bits) 0.9 ******** 0.7 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel GGAGAAAT consensus T A sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif KGAGAAAW MEME-5 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr6:26458056-26458136 23 8.65e-06 CAGCAACTGC TGAGAAAT AAGGTTCGAC chr6:26383251-26383331 2 8.65e-06 C TGAGAAAT AAGGCTCGAG chr6:26421533-26421613 23 8.65e-06 TAGTAACTGC TGAGAAAT AAGGCTCGAC chr6:26474107-26474187 39 8.65e-06 CAGCAACTGA TGAGAAAT GGTACCTCTG chr11:1372887-1372967 50 8.65e-06 TCACTGCCTT TGAGAAAT GACCTGTTGT chr7:99277242-99277322 15 1.96e-05 AAGGTGGATG GGAGAAAT GCTTATTTAT chr3:13044284-13044364 64 1.96e-05 gacaggatgt ggagaaat ggaaaccct chr6:15211390-15211470 31 3.89e-05 agactagtgg ggagaaaa ccagcagtga chr20:52369809-52369889 15 3.89e-05 tatagatgcg ggaGAAAA TGCATAAAAG chr19:50093561-50093641 16 3.89e-05 GTTGAAGGGG GGAGAAAA ACAGCCAGAT chr3:112360097-112360177 38 3.89e-05 TACTTTGGAA GGAGAAAA TTCTCAGATT -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif KGAGAAAW MEME-5 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr6:26458056-26458136 8.6e-06 22_[+5]_50 chr6:26383251-26383331 8.6e-06 1_[+5]_71 chr6:26421533-26421613 8.6e-06 22_[+5]_50 chr6:26474107-26474187 8.6e-06 38_[+5]_34 chr11:1372887-1372967 8.6e-06 49_[+5]_23 chr7:99277242-99277322 2e-05 14_[+5]_58 chr3:13044284-13044364 2e-05 63_[+5]_9 chr6:15211390-15211470 3.9e-05 30_[+5]_42 chr20:52369809-52369889 3.9e-05 14_[+5]_58 chr19:50093561-50093641 3.9e-05 15_[+5]_57 chr3:112360097-112360177 3.9e-05 37_[+5]_35 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif KGAGAAAW MEME-5 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF KGAGAAAW width=8 seqs=11 chr6:26458056-26458136 ( 23) TGAGAAAT 1 chr6:26383251-26383331 ( 2) TGAGAAAT 1 chr6:26421533-26421613 ( 23) TGAGAAAT 1 chr6:26474107-26474187 ( 39) TGAGAAAT 1 chr11:1372887-1372967 ( 50) TGAGAAAT 1 chr7:99277242-99277322 ( 15) GGAGAAAT 1 chr3:13044284-13044364 ( 64) GGAGAAAT 1 chr6:15211390-15211470 ( 31) GGAGAAAA 1 chr20:52369809-52369889 ( 15) GGAGAAAA 1 chr19:50093561-50093641 ( 16) GGAGAAAA 1 chr3:112360097-112360177 ( 38) GGAGAAAA 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif KGAGAAAW MEME-5 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 11.0506 E= 4.0e+002 -1010 -1010 96 104 -1010 -1010 184 -1010 220 -1010 -1010 -1010 -1010 -1010 184 -1010 220 -1010 -1010 -1010 220 -1010 -1010 -1010 220 -1010 -1010 -1010 74 -1010 -1010 153 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif KGAGAAAW MEME-5 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 11 E= 4.0e+002 0.000000 0.000000 0.545455 0.454545 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.363636 0.000000 0.000000 0.636364 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif KGAGAAAW MEME-5 regular expression -------------------------------------------------------------------------------- [GT]GAGAAA[TA] -------------------------------------------------------------------------------- Time 20.15 secs. ******************************************************************************** ******************************************************************************** SUMMARY OF MOTIFS ******************************************************************************** -------------------------------------------------------------------------------- Combined block diagrams: non-overlapping sites with p-value < 0.0001 -------------------------------------------------------------------------------- SEQUENCE NAME COMBINED P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr22:21987029-21987109 6.34e-01 80 chr19:5352480-5352560 4.85e-01 80 chr19:41283492-41283572 8.18e-01 80 chr19:45430462-45430542 2.00e-03 23_[+3(8.60e-05)]_31_[+2(1.46e-05)]_\ 10 chr11:1372887-1372967 4.72e-02 49_[+5(8.65e-06)]_23 chr11:61266581-61266661 6.53e-01 80 chr6:32812465-32812545 2.05e-01 40_[+3(3.27e-05)]_32 chr20:305999-306079 3.80e-02 29_[+3(3.27e-05)]_43 chr1:181002978-181003058 9.15e-03 39_[+3(1.44e-05)]_33 chr14:102176555-10217663 1.24e-01 80 chr14:23120275-23120355 3.03e-01 80 chr16:9085927-9086007 7.44e-01 80 chr22:21984252-21984332 9.96e-01 80 chr3:112360097-112360177 1.27e-01 37_[+5(3.89e-05)]_35 chr6:37465154-37465234 6.44e-01 80 chr22:21983656-21983736 9.69e-01 80 chr6:26474107-26474187 1.01e-06 26_[+3(3.27e-05)]_4_[+5(8.65e-06)]_\ 10_[+4(1.44e-05)]_16 chr7:75947380-75947460 8.93e-02 55_[+3(1.44e-05)]_17 chr6:26421533-26421613 1.50e-07 10_[+3(8.60e-05)]_4_[+5(8.65e-06)]_\ 13_[+2(1.46e-05)]_14_[+4(3.28e-05)]_7 chrX:153191113-153191193 5.26e-01 80 chr19:50934963-50935043 8.04e-02 43_[+3(5.12e-05)]_29 chr5:170814799-170814879 2.21e-01 25_[+1(6.50e-05)]_47 chr22:29548881-29548961 2.15e-01 80 chr6:27835319-27835399 3.83e-02 70_[+1(1.23e-05)]_2 chr22:21996311-21996391 8.40e-01 80 chr11:117997181-11799726 3.87e-01 80 chr2:108972762-108972842 6.80e-02 5_[+1(3.68e-05)]_67 chr6:28688229-28688309 6.11e-01 80 chr11:122932808-12293288 7.43e-01 80 chr11:72433617-72433697 2.77e-03 13_[+3(5.12e-05)]_29_[+2(1.46e-05)]_\ 22 chr1:249133168-249133248 1.37e-03 23_[+3(3.27e-05)]_32_[+2(1.46e-05)]_\ 9 chr12:25086868-25086948 1.29e-01 80 chr1:207779183-207779263 2.28e-01 80 chr7:2913726-2913806 5.24e-01 80 chr10:126107449-12610752 2.24e-01 80 chr22:50555785-50555865 2.39e-01 80 chr13:108653468-10865354 9.82e-01 80 chr18:9014252-9014332 7.58e-01 80 chr19:45418391-45418471 4.38e-03 49_[+2(1.46e-05)]_23 chr6:26383251-26383331 5.48e-05 1_[+5(8.65e-06)]_37_[+4(3.28e-05)]_\ 26 chr19:56028419-56028499 9.70e-01 80 chr10:111971032-11197111 8.50e-02 14_[+4(1.44e-05)]_58 chr6:37391702-37391782 1.45e-01 80 chr18:75705635-75705715 1.08e-02 67_[+1(3.68e-05)]_5 chr11:120107295-12010737 9.79e-01 80 chr19:51182755-51182835 2.67e-03 38_[+4(1.44e-05)]_34 chr1:151319779-151319859 4.95e-01 80 chr1:71513457-71513537 3.21e-02 62_[+1(3.68e-05)]_10 chr1:46049170-46049250 3.20e-02 16_[+4(1.44e-05)]_56 chr2:158115212-158115292 8.12e-01 80 chr1:149215268-149215348 5.53e-01 80 chr19:50093561-50093641 1.48e-01 15_[+5(3.89e-05)]_57 chr11:129939747-12993982 3.55e-01 80 chr19:2042303-2042383 9.97e-01 80 chr11:6640668-6640748 4.56e-02 36_[+3(8.60e-05)]_36 chr3:129118796-129118876 3.27e-01 80 chr5:16528551-16528631 3.59e-02 80 chr12:6643666-6643746 8.74e-01 80 chr8:101734296-101734376 7.86e-01 80 chr11:121097253-12109733 7.03e-01 80 chr3:25706478-25706558 8.28e-02 18_[+4(3.28e-05)]_54 chr2:30884150-30884230 1.23e-01 80 chr17:79008923-79009003 1.00e+00 80 chr19:49078078-49078158 1.02e-01 80 chr17:17255671-17255751 6.70e-01 80 chrX:41193377-41193457 9.05e-01 80 chr6:29617898-29617978 1.72e-01 80 chr3:24537170-24537250 9.93e-01 80 chr5:140699862-140699942 6.57e-01 80 chr9:130186373-130186453 1.67e-01 80 chr22:30841048-30841128 4.83e-01 80 chr6:30457154-30457234 2.90e-02 72_[+4(1.44e-05)] chr1:20204943-20205023 3.31e-01 80 chr6:28188416-28188496 9.64e-01 80 chr5:43040529-43040609 8.12e-02 80 chr9:123639837-123639917 2.84e-01 80 chr15:93426014-93426094 5.31e-01 80 chr6:31430822-31430902 4.02e-01 80 chr10:23344715-23344795 4.33e-02 80 chr11:65222706-65222786 9.97e-01 80 chr8:125827944-125828024 1.60e-01 80 chr5:137801117-137801197 2.14e-01 80 chr2:30454360-30454440 1.63e-01 80 chr21:15918600-15918680 8.68e-01 80 chr1:33430381-33430461 5.86e-02 56_[+1(9.28e-05)]_16 chr6:3118551-3118631 9.43e-01 80 chr20:52369809-52369889 3.97e-02 14_[+5(3.89e-05)]_58 chr6:15211390-15211470 3.43e-02 30_[+5(3.89e-05)]_42 chr3:13044284-13044364 2.24e-02 63_[+5(1.96e-05)]_9 chr11:64937652-64937732 2.13e-02 21_[+1(1.23e-05)]_51 chr11:2398502-2398582 6.41e-01 80 chr6:28677830-28677910 7.33e-01 80 chr19:51111386-51111466 1.05e-01 44_[+2(1.46e-05)]_28 chr14:102553348-10255342 1.08e-01 56_[+1(5.25e-05)]_16 chr6:26033841-26033921 3.94e-03 67_[+2(2.59e-05)]_5 chr11:62495376-62495456 2.46e-02 2_[+3(3.27e-05)]_70 chr6:27775706-27775786 5.39e-02 26_[+1(1.23e-05)]_46 chr11:62619293-62619373 2.07e-01 80 chr6:27833050-27833130 1.12e-01 80 chr10:70320051-70320131 7.79e-01 80 chr14:20937533-20937613 4.90e-01 80 chr19:48948734-48948814 8.31e-02 80 chr17:38136745-38136825 2.62e-02 3_[+3(8.60e-05)]_69 chr17:41393221-41393301 3.92e-01 80 chr12:108513212-10851329 2.46e-03 80 chr22:42196640-42196720 9.61e-01 80 chr6:42952197-42952277 6.29e-02 80 chr10:14880035-14880115 2.01e-02 52_[+2(5.21e-05)]_20 chr1:100828488-100828568 6.82e-02 80 chr12:50505529-50505609 2.91e-03 67_[+2(1.46e-05)]_5 chr1:32801811-32801891 2.47e-01 44_[+1(6.50e-05)]_28 chr19:36103582-36103662 2.78e-01 12_[+3(8.60e-05)]_60 chr9:113018755-113018835 5.11e-02 55_[+1(3.68e-05)]_17 chr8:37963422-37963502 8.47e-01 80 chr5:173615545-173615625 8.31e-02 80 chr1:149858224-149858304 5.33e-02 31_[+1(3.68e-05)]_41 chr1:76251907-76251987 3.17e-01 80 chr6:26365320-26365400 4.22e-03 43_[+3(3.27e-05)]_4_[+5(8.05e-05)]_\ 17 chr6:27100537-27100617 5.26e-02 4_[+1(9.28e-05)]_48_[+1(5.25e-05)]_\ 12 chr6:30843363-30843443 1.86e-01 80 chr20:26189279-26189359 9.92e-01 80 chr21:36261027-36261107 1.98e-02 51_[+4(3.28e-05)]_21 chr3:128206750-128206830 5.76e-02 62_[+4(1.44e-05)]_10 chr3:150320997-150321077 4.29e-01 80 chr6:26251823-26251903 6.11e-01 80 chr6:32407524-32407604 2.93e-03 31_[+3(1.44e-05)]_41 chr19:5309003-5309083 8.15e-01 80 chr4:38324978-38325058 1.67e-02 31_[+1(3.68e-05)]_41 chr19:1269289-1269369 8.43e-01 80 chr17:20771805-20771885 5.71e-01 80 chr9:106856225-106856305 3.56e-01 80 chr1:52796048-52796128 4.35e-01 80 chr10:3214935-3215015 8.42e-01 80 chr17:21515824-21515904 1.03e-01 80 chr14:51135228-51135308 7.08e-01 80 chrX:118602343-118602423 5.65e-03 33_[+1(1.23e-05)]_39 chr6:134495966-134496046 3.40e-02 58_[+1(2.44e-05)]_14 chr20:47662803-47662883 9.41e-01 80 chr3:129035089-129035169 2.01e-01 80 chr16:27210385-27210465 5.24e-04 13_[+1(2.44e-05)]_59 chr19:9676715-9676795 8.26e-01 80 chr11:129872766-12987284 1.39e-03 4_[+3(5.12e-05)]_68 chr5:162864554-162864634 2.52e-01 80 chr7:104655506-104655586 8.69e-01 80 chr6:31865537-31865617 6.93e-01 80 chr9:123638283-123638363 6.65e-01 80 chr2:232573158-232573238 2.34e-02 80 chr1:210547595-210547675 1.24e-01 80 chr6:26235185-26235265 1.11e-01 55_[+1(5.25e-05)]_17 chr7:99277242-99277322 1.27e-02 14_[+5(1.96e-05)]_58 chr3:151986716-151986796 8.53e-01 80 chr21:33104329-33104409 7.28e-01 80 chr17:45253851-45253931 1.88e-02 36_[+1(7.72e-05)]_36 chr19:59055791-59055871 9.66e-01 80 chr1:118148646-118148726 9.38e-01 80 chr22:22335089-22335169 9.59e-01 80 chr3:70048857-70048937 5.09e-01 80 chr21:33031970-33032050 2.03e-01 1_[+1(9.28e-05)]_71 chr1:200610204-200610284 5.63e-01 80 chr16:8159625-8159705 3.47e-01 80 chr2:61763887-61763967 8.50e-01 80 chr11:5526828-5526908 3.40e-01 80 chr22:23470757-23470837 3.74e-02 80 chr16:57717033-57717113 4.52e-01 80 chr1:149224305-149224385 9.86e-01 80 chr1:149858429-149858509 8.25e-02 8_[+1(9.28e-05)]_64 chr15:69745103-69745183 6.90e-01 80 chr17:75315512-75315592 7.61e-01 80 chr5:27217794-27217874 4.64e-02 [+1(2.44e-05)]_72 chr5:90676860-90676940 1.24e-01 80 chr10:14227409-14227489 1.82e-01 80 chr5:78884620-78884700 1.60e-01 80 chr17:56744009-56744089 1.50e-02 65_[+3(3.27e-05)]_7 chr22:22001192-22001272 3.61e-01 80 chr22:21979301-21979381 2.45e-01 80 chr1:12717576-12717656 6.24e-01 80 chr15:45003634-45003714 1.53e-02 31_[+2(1.46e-05)]_41 chr16:69760396-69760476 9.96e-01 80 chr1:160696114-160696194 1.84e-01 80 chr2:183903681-183903761 2.55e-01 80 chr17:42147520-42147600 7.77e-01 80 chr21:46493706-46493786 9.35e-01 80 chrX:123096959-123097039 2.01e-01 80 chr5:56205850-56205930 9.91e-01 80 chr6:26158086-26158166 1.05e-01 80 chr22:43411346-43411426 3.82e-02 80 chr3:100120388-100120468 3.53e-01 80 chr14:62162194-62162274 9.99e-01 80 chr16:14724214-14724294 5.76e-01 80 chrX:12993222-12993302 5.58e-01 80 chr4:127877188-127877268 5.69e-01 80 chr5:179050649-179050729 4.38e-01 80 chr6:37137939-37138019 9.56e-01 80 chr4:111115149-111115229 3.85e-03 6_[+2(2.59e-05)]_66 chr22:23596232-23596312 3.89e-01 80 chr2:152118451-152118531 8.26e-01 80 chr16:2955361-2955441 6.43e-01 80 chr19:2476065-2476145 5.09e-02 27_[+1(2.44e-05)]_45 chr22:22006432-22006512 9.58e-01 80 chr6:31795481-31795561 5.47e-02 3_[+1(2.44e-05)]_69 chr11:62341312-62341392 6.24e-01 80 chr13:52027155-52027235 8.33e-01 80 chr2:9771340-9771420 7.16e-01 80 chr15:75052951-75053031 4.40e-01 80 chr15:64673607-64673687 3.64e-01 80 chr17:62502372-62502452 1.58e-02 80 chr19:2051210-2051290 2.82e-01 80 chr6:26458056-26458136 6.59e-08 10_[+3(3.27e-05)]_4_[+5(8.65e-06)]_\ 13_[+2(1.46e-05)]_14_[+4(3.28e-05)]_7 chr13:27825607-27825687 2.92e-01 80 chr6:26158294-26158374 1.42e-01 80 chr20:32891110-32891190 1.69e-01 80 chr17:79479782-79479862 2.86e-01 80 chr4:681236-681316 8.24e-01 80 chr22:23536036-23536116 9.67e-01 80 chr1:59249672-59249752 8.91e-01 80 chr9:131940507-131940587 8.88e-02 80 chrX:48380182-48380262 9.55e-01 80 chr15:88120126-88120206 1.85e-02 80 chr6:42713758-42713838 3.47e-02 53_[+2(5.21e-05)]_19 chr1:100503635-100503715 8.61e-01 80 chr10:11936649-11936729 9.14e-01 80 chr5:90679094-90679174 4.60e-01 80 chr6:31789952-31790032 1.52e-01 80 chr11:64646062-64646142 1.42e-01 80 chr1:40042408-40042488 8.85e-01 80 chr22:22133081-22133161 5.49e-01 80 chr22:19710297-19710377 7.92e-01 80 chr1:147735700-147735780 4.77e-01 80 chr19:34895151-34895231 8.14e-01 80 chr22:22337168-22337248 9.81e-01 80 chr6:26124353-26124433 1.38e-02 14_[+1(2.44e-05)]_58 chr19:5791310-5791390 3.26e-04 10_[+1(1.23e-05)]_62 chr6:31625965-31626045 6.09e-01 80 chr5:149790244-149790324 2.17e-01 80 chr1:23885965-23886045 5.94e-01 80 chr10:16933851-16933931 2.50e-01 80 chr17:17739672-17739752 9.82e-01 80 chr2:145116664-145116744 1.45e-01 80 chr17:33894874-33894954 4.31e-01 80 chr19:6536225-6536305 1.92e-02 22_[+3(5.12e-05)]_50 chr6:42946902-42946982 9.82e-01 80 chr14:23426284-23426364 6.38e-01 80 chr8:97247721-97247801 4.22e-01 80 chr12:49525137-49525217 3.43e-01 80 chr11:93474613-93474693 2.19e-02 80 chr14:20811555-20811635 2.95e-01 80 chr4:119199893-119199973 2.80e-01 80 chr15:91412988-91413068 2.19e-01 80 chrX:129116577-129116657 9.90e-01 80 chr1:68150851-68150931 2.93e-01 80 -------------------------------------------------------------------------------- ******************************************************************************** ******************************************************************************** Stopped because requested number of motifs (5) found. ******************************************************************************** CPU: c22n09.farnam.hpc.yale.internal ********************************************************************************