******************************************************************************** MEME - Motif discovery tool ******************************************************************************** MEME version 5.3.3 (Release date: Sun Feb 7 15:39:52 2021 -0800) For further information on how to interpret these results please access https://meme-suite.org/meme. To get a copy of the MEME Suite software please access https://meme-suite.org. ******************************************************************************** ******************************************************************************** REFERENCE ******************************************************************************** If you use this program in your research, please cite: Timothy L. Bailey and Charles Elkan, "Fitting a mixture model by expectation maximization to discover motifs in biopolymers", Proceedings of the Second International Conference on Intelligent Systems for Molecular Biology, pp. 28-36, AAAI Press, Menlo Park, California, 1994. ******************************************************************************** ******************************************************************************** TRAINING SET ******************************************************************************** PRIMARY SEQUENCES= ../result/final_prediction/K562/fasta/RankLinear0.6_40/GTF2B.fasta CONTROL SEQUENCES= --none-- ALPHABET= ACGT Sequence name Weight Length Sequence name Weight Length ------------- ------ ------ ------------- ------ ------ chr5:78884599-78884679 1.0000 80 chr19:5352468-5352548 1.0000 80 chr1:167523628-167523708 1.0000 80 chr12:122908420-12290850 1.0000 80 chr8:49959358-49959438 1.0000 80 chr11:66635988-66636068 1.0000 80 chr18:9014262-9014342 1.0000 80 chr3:69128567-69128647 1.0000 80 chr14:75413235-75413315 1.0000 80 chr15:82246923-82247003 1.0000 80 chr5:61561552-61561632 1.0000 80 chr11:2398495-2398575 1.0000 80 chr14:56683750-56683830 1.0000 80 chr19:10949226-10949306 1.0000 80 chr7:103020197-103020277 1.0000 80 chr5:16528537-16528617 1.0000 80 chr15:96679024-96679104 1.0000 80 chr12:25086875-25086955 1.0000 80 chr17:26421264-26421344 1.0000 80 chr6:29782909-29782989 1.0000 80 chr19:17516358-17516438 1.0000 80 chr1:37791761-37791841 1.0000 80 chr12:50615369-50615449 1.0000 80 chrX:118824868-118824948 1.0000 80 chr17:10694432-10694512 1.0000 80 chr17:42147485-42147565 1.0000 80 chr11:61266567-61266647 1.0000 80 chr1:211779873-211779953 1.0000 80 chr6:119031241-119031321 1.0000 80 chr5:132002088-132002168 1.0000 80 chr11:1372886-1372966 1.0000 80 chr18:74587476-74587556 1.0000 80 chr2:108972755-108972835 1.0000 80 chr14:23120280-23120360 1.0000 80 chr3:112360073-112360153 1.0000 80 chr13:45266412-45266492 1.0000 80 chr1:46503148-46503228 1.0000 80 chr2:191137236-191137316 1.0000 80 chr19:1727559-1727639 1.0000 80 chr10:70847795-70847875 1.0000 80 chr17:15083698-15083778 1.0000 80 chr12:9517051-9517131 1.0000 80 chr6:37391719-37391799 1.0000 80 chr2:20646769-20646849 1.0000 80 chr12:33137043-33137123 1.0000 80 chr6:7723986-7724066 1.0000 80 chr1:25215118-25215198 1.0000 80 chr19:55686220-55686300 1.0000 80 chr16:9085899-9085979 1.0000 80 chr5:81574452-81574532 1.0000 80 chr20:52369809-52369889 1.0000 80 chr19:8226086-8226166 1.0000 80 chr6:28688243-28688323 1.0000 80 chr4:38325046-38325126 1.0000 80 chr16:88851547-88851627 1.0000 80 chr5:173615547-173615627 1.0000 80 chr13:30756449-30756529 1.0000 80 chrX:153191117-153191197 1.0000 80 chr14:57476681-57476761 1.0000 80 chr17:76275870-76275950 1.0000 80 chr10:23344768-23344848 1.0000 80 chr11:122932805-12293288 1.0000 80 chr9:130186345-130186425 1.0000 80 chr17:45253894-45253974 1.0000 80 chr22:30627085-30627165 1.0000 80 chr2:220549748-220549828 1.0000 80 chr17:6843680-6843760 1.0000 80 chr1:167906744-167906824 1.0000 80 chr15:75052989-75053069 1.0000 80 chr1:42344258-42344338 1.0000 80 chr1:207779174-207779254 1.0000 80 chr7:39761696-39761776 1.0000 80 chr5:170814778-170814858 1.0000 80 chr14:102176553-10217663 1.0000 80 chr5:118753813-118753893 1.0000 80 chr11:120107294-12010737 1.0000 80 chr22:50555772-50555852 1.0000 80 chr17:17255710-17255790 1.0000 80 chr14:91016440-91016520 1.0000 80 chr7:16505552-16505632 1.0000 80 chr3:71113081-71113161 1.0000 80 chr14:34420262-34420342 1.0000 80 chr1:236451499-236451579 1.0000 80 chr4:989698-989778 1.0000 80 chr11:117997196-11799727 1.0000 80 chr18:75705636-75705716 1.0000 80 chr1:149859691-149859771 1.0000 80 chr16:27210269-27210349 1.0000 80 chr11:66491255-66491335 1.0000 80 chr17:56743998-56744078 1.0000 80 chr2:188419191-188419271 1.0000 80 chr17:5522748-5522828 1.0000 80 chr3:129118765-129118845 1.0000 80 chr1:200610189-200610269 1.0000 80 chr12:21810761-21810841 1.0000 80 chr10:70320040-70320120 1.0000 80 chr17:80326294-80326374 1.0000 80 chr1:160696102-160696182 1.0000 80 chr7:39761899-39761979 1.0000 80 chrX:135838776-135838856 1.0000 80 chr2:30884126-30884206 1.0000 80 chr14:35836740-35836820 1.0000 80 chr22:29548874-29548954 1.0000 80 chr2:61763848-61763928 1.0000 80 chr11:61129304-61129384 1.0000 80 chr16:57717016-57717096 1.0000 80 chr7:2913701-2913781 1.0000 80 chr4:31998995-31999075 1.0000 80 chr6:27833024-27833104 1.0000 80 chr19:48948710-48948790 1.0000 80 chr1:20204917-20204997 1.0000 80 chr8:8702663-8702743 1.0000 80 chr17:27188961-27189041 1.0000 80 chr6:27286842-27286922 1.0000 80 chr6:56884316-56884396 1.0000 80 chr6:43738356-43738436 1.0000 80 chr17:39684604-39684684 1.0000 80 chr17:41953268-41953348 1.0000 80 chr7:133896172-133896252 1.0000 80 chr12:102071964-10207204 1.0000 80 chr1:149215265-149215345 1.0000 80 chr3:101568296-101568376 1.0000 80 chr22:38053895-38053975 1.0000 80 chr4:83668203-83668283 1.0000 80 chrX:41193353-41193433 1.0000 80 chr6:28833632-28833712 1.0000 80 chr19:45971241-45971321 1.0000 80 chr21:40277685-40277765 1.0000 80 chr16:8159629-8159709 1.0000 80 chr12:68900650-68900730 1.0000 80 chr3:156805710-156805790 1.0000 80 chr12:8088730-8088810 1.0000 80 chr17:78992117-78992197 1.0000 80 chr12:113772877-11377295 1.0000 80 chr3:49449599-49449679 1.0000 80 chr4:37563264-37563344 1.0000 80 chr3:24537171-24537251 1.0000 80 chr3:60263269-60263349 1.0000 80 chr6:27835330-27835410 1.0000 80 chr14:73374655-73374735 1.0000 80 chr9:137098192-137098272 1.0000 80 chr7:120627931-120628011 1.0000 80 chr11:10476634-10476714 1.0000 80 chr6:37465100-37465180 1.0000 80 chr6:27775685-27775765 1.0000 80 chr3:191143219-191143299 1.0000 80 chr3:152552589-152552669 1.0000 80 chr6:52529180-52529260 1.0000 80 chr6:3939463-3939543 1.0000 80 chr6:15211381-15211461 1.0000 80 chr11:5291115-5291195 1.0000 80 chr1:71513458-71513538 1.0000 80 chr3:138582507-138582587 1.0000 80 chr3:71922266-71922346 1.0000 80 chr6:130031281-130031361 1.0000 80 chr1:226252054-226252134 1.0000 80 chr3:13044294-13044374 1.0000 80 chr17:21515832-21515912 1.0000 80 chr5:89705114-89705194 1.0000 80 chr15:93354038-93354118 1.0000 80 chr4:142253712-142253792 1.0000 80 chr14:20801422-20801502 1.0000 80 chr11:57413253-57413333 1.0000 80 chr14:20937531-20937611 1.0000 80 chr3:197211489-197211569 1.0000 80 chr22:35627034-35627114 1.0000 80 chr1:245725129-245725209 1.0000 80 chr1:36616545-36616625 1.0000 80 chr11:5526834-5526914 1.0000 80 chr1:197965173-197965253 1.0000 80 chr5:137801101-137801181 1.0000 80 chr6:26033831-26033911 1.0000 80 chr2:20101356-20101436 1.0000 80 chr9:91924709-91924789 1.0000 80 chr16:89989705-89989785 1.0000 80 chr21:36260978-36261058 1.0000 80 chr19:8579110-8579190 1.0000 80 chr5:53609396-53609476 1.0000 80 chr6:106258910-106258990 1.0000 80 chr12:6643611-6643691 1.0000 80 chr10:82463467-82463547 1.0000 80 chr11:65222699-65222779 1.0000 80 chr20:31220759-31220839 1.0000 80 chr11:64053177-64053257 1.0000 80 chr15:88120146-88120226 1.0000 80 chr13:111367641-11136772 1.0000 80 chr3:24561430-24561510 1.0000 80 chr8:125827951-125828031 1.0000 80 chr1:16400393-16400473 1.0000 80 chr4:127877193-127877273 1.0000 80 chr9:19102885-19102965 1.0000 80 chr8:8412713-8412793 1.0000 80 chr2:228331205-228331285 1.0000 80 chr1:32801810-32801890 1.0000 80 chr17:74639807-74639887 1.0000 80 chr6:30843313-30843393 1.0000 80 chr4:40200037-40200117 1.0000 80 chr19:5434708-5434788 1.0000 80 chr3:160938935-160939015 1.0000 80 chr1:17222376-17222456 1.0000 80 chr19:5309003-5309083 1.0000 80 chr1:228645774-228645854 1.0000 80 chr17:40575264-40575344 1.0000 80 chrX:118925629-118925709 1.0000 80 chr6:28863324-28863404 1.0000 80 chr14:68161519-68161599 1.0000 80 chr8:74205821-74205901 1.0000 80 chrX:12993169-12993249 1.0000 80 chr4:787415-787495 1.0000 80 chr17:79008917-79008997 1.0000 80 chr16:46776893-46776973 1.0000 80 chr1:76251905-76251985 1.0000 80 chr17:57604856-57604936 1.0000 80 chr6:26020628-26020708 1.0000 80 chr6:28188457-28188537 1.0000 80 chr2:149402960-149403040 1.0000 80 chr11:93517407-93517487 1.0000 80 chr1:149858384-149858464 1.0000 80 chr21:45158607-45158687 1.0000 80 chr20:32891143-32891223 1.0000 80 chr10:14227399-14227479 1.0000 80 chr2:178044356-178044436 1.0000 80 chr19:1269289-1269369 1.0000 80 chr19:13953691-13953771 1.0000 80 chr2:70336103-70336183 1.0000 80 chr17:20771799-20771879 1.0000 80 chr9:101552138-101552218 1.0000 80 chr10:17271197-17271277 1.0000 80 chr1:47800423-47800503 1.0000 80 chr2:202047817-202047897 1.0000 80 chr10:32667723-32667803 1.0000 80 chr1:165798241-165798321 1.0000 80 chr1:210547602-210547682 1.0000 80 chr20:47662801-47662881 1.0000 80 chr14:35451537-35451617 1.0000 80 chr17:37780068-37780148 1.0000 80 chr15:64673605-64673685 1.0000 80 chr11:11833065-11833145 1.0000 80 chr2:45838331-45838411 1.0000 80 chr3:70048858-70048938 1.0000 80 chr7:100487453-100487533 1.0000 80 chr1:100828658-100828738 1.0000 80 chr1:113247857-113247937 1.0000 80 chr10:45474229-45474309 1.0000 80 chr5:72794132-72794212 1.0000 80 chr20:10415220-10415300 1.0000 80 chr6:26235179-26235259 1.0000 80 chr10:121356652-12135673 1.0000 80 chr15:44719138-44719218 1.0000 80 chr6:95967199-95967279 1.0000 80 ******************************************************************************** ******************************************************************************** COMMAND LINE SUMMARY ******************************************************************************** This information can also be useful in the event you wish to report a problem with the MEME software. command: meme -oc ../result/final_prediction/K562/inference_raw/MEME/RankLinear0.6_40_GTF2B/ -dna -nmotifs 5 -w 8 -maxsize 250000 -nostatus ../result/final_prediction/K562/fasta/RankLinear0.6_40/GTF2B.fasta model: mod= zoops nmotifs= 5 evt= inf objective function: em= E-value of product of p-values starts= E-value of product of p-values strands: + width: minw= 8 maxw= 8 nsites: minsites= 2 maxsites= 250 wnsites= 0.8 theta: spmap= uni spfuzz= 0.5 em: prior= dirichlet b= 0.01 maxiter= 50 distance= 1e-05 trim: wg= 11 ws= 1 endgaps= yes data: n= 20000 N= 250 sample: seed= 0 hsfrac= 0 searchsize= 20000 norand= no csites= 1000 Letter frequencies in dataset: A 0.242 C 0.264 G 0.261 T 0.232 Background letter frequencies (from file dataset with add-one prior applied): A 0.243 C 0.264 G 0.261 T 0.232 Background model order: 0 ******************************************************************************** ******************************************************************************** MOTIF GGGAGGAG MEME-1 width = 8 sites = 17 llr = 160 E-value = 8.4e+001 ******************************************************************************** -------------------------------------------------------------------------------- Motif GGGAGGAG MEME-1 Description -------------------------------------------------------------------------------- Simplified A ::3a:1a: pos.-specific C :::::2:: probability G aa7:a6:a matrix T :::::::: bits 2.1 * * 1.9 ** ** ** 1.7 ** ** ** 1.5 ** ** ** Relative 1.3 ** ** ** Entropy 1.1 ***** ** (13.6 bits) 0.8 ***** ** 0.6 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel GGGAGGAG consensus A C sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GGGAGGAG MEME-1 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr17:37780068-37780148 65 1.87e-05 CATCTTGCTT GGGAGGAG GGAGGGAC chr9:19102885-19102965 54 1.87e-05 AGGCGTCCGA GGGAGGAG GGACTTCCGG chr22:35627034-35627114 29 1.87e-05 gaagtgaagg gggaggag ccccttataa chr12:21810761-21810841 18 1.87e-05 TCTGCAAGGA GGGAGGAG GGGGCGGGGC chr3:71113081-71113161 7 1.87e-05 TACTTG GGGAGGAG AGGGGTAAAA chr1:46503148-46503228 30 1.87e-05 AAATGGGGAT GGGAGGAG GAAGCAGAGA chr14:68161519-68161599 43 3.60e-05 GCCCACCTGG GGAAGGAG TGTGTCTGTC chr3:152552589-152552669 34 3.60e-05 GGCGGAAGAG GGAAGGAG CGCTCGCGGG chr5:81574452-81574532 65 3.60e-05 GGTCAGAGTA GGAAGGAG TCGCTGAG chr3:112360073-112360153 58 3.60e-05 ACTGTACTTT GGAAGGAG AAAATTCTCA chr7:103020197-103020277 16 3.60e-05 CACAGAAGCA GGAAGGAG CTTAAATGGA chr1:113247857-113247937 25 5.49e-05 CAACCAGGCA GGGAGCAG TTAAGAAAGC chr6:3939463-3939543 33 5.49e-05 AATCAGGACT GGGAGCAG CTATTGCCAG chr17:17255710-17255790 64 5.49e-05 GGACAGGCGT GGGAGCAG TCTCACCAG chr17:15083698-15083778 10 5.49e-05 TCCTTGAAA GGGAGCAG AACCTGTAAG chr4:40200037-40200117 20 7.23e-05 GCAGGCACTG GGGAGAAG TGACCCCATT chr3:60263269-60263349 5 7.23e-05 agct gggagaag tcgccatttg -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GGGAGGAG MEME-1 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr17:37780068-37780148 1.9e-05 64_[+1]_8 chr9:19102885-19102965 1.9e-05 53_[+1]_19 chr22:35627034-35627114 1.9e-05 28_[+1]_44 chr12:21810761-21810841 1.9e-05 17_[+1]_55 chr3:71113081-71113161 1.9e-05 6_[+1]_66 chr1:46503148-46503228 1.9e-05 29_[+1]_43 chr14:68161519-68161599 3.6e-05 42_[+1]_30 chr3:152552589-152552669 3.6e-05 33_[+1]_39 chr5:81574452-81574532 3.6e-05 64_[+1]_8 chr3:112360073-112360153 3.6e-05 57_[+1]_15 chr7:103020197-103020277 3.6e-05 15_[+1]_57 chr1:113247857-113247937 5.5e-05 24_[+1]_48 chr6:3939463-3939543 5.5e-05 32_[+1]_40 chr17:17255710-17255790 5.5e-05 63_[+1]_9 chr17:15083698-15083778 5.5e-05 9_[+1]_63 chr4:40200037-40200117 7.2e-05 19_[+1]_53 chr3:60263269-60263349 7.2e-05 4_[+1]_68 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GGGAGGAG MEME-1 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF GGGAGGAG width=8 seqs=17 chr17:37780068-37780148 ( 65) GGGAGGAG 1 chr9:19102885-19102965 ( 54) GGGAGGAG 1 chr22:35627034-35627114 ( 29) GGGAGGAG 1 chr12:21810761-21810841 ( 18) GGGAGGAG 1 chr3:71113081-71113161 ( 7) GGGAGGAG 1 chr1:46503148-46503228 ( 30) GGGAGGAG 1 chr14:68161519-68161599 ( 43) GGAAGGAG 1 chr3:152552589-152552669 ( 34) GGAAGGAG 1 chr5:81574452-81574532 ( 65) GGAAGGAG 1 chr3:112360073-112360153 ( 58) GGAAGGAG 1 chr7:103020197-103020277 ( 16) GGAAGGAG 1 chr1:113247857-113247937 ( 25) GGGAGCAG 1 chr6:3939463-3939543 ( 33) GGGAGCAG 1 chr17:17255710-17255790 ( 64) GGGAGCAG 1 chr17:15083698-15083778 ( 10) GGGAGCAG 1 chr4:40200037-40200117 ( 20) GGGAGAAG 1 chr3:60263269-60263349 ( 5) GGGAGAAG 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GGGAGGAG MEME-1 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 9.29533 E= 8.4e+001 -1073 -1073 194 -1073 -1073 -1073 194 -1073 28 -1073 143 -1073 204 -1073 -1073 -1073 -1073 -1073 194 -1073 -104 -17 131 -1073 204 -1073 -1073 -1073 -1073 -1073 194 -1073 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GGGAGGAG MEME-1 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 17 E= 8.4e+001 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.294118 0.000000 0.705882 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.117647 0.235294 0.647059 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GGGAGGAG MEME-1 regular expression -------------------------------------------------------------------------------- GG[GA]AG[GC]AG -------------------------------------------------------------------------------- Time 4.82 secs. ******************************************************************************** ******************************************************************************** MOTIF CTTGTCTG MEME-2 width = 8 sites = 10 llr = 106 E-value = 1.8e+002 ******************************************************************************** -------------------------------------------------------------------------------- Motif CTTGTCTG MEME-2 Description -------------------------------------------------------------------------------- Simplified A :::::::: pos.-specific C a::3:a:: probability G :::7:::a matrix T :aa:a:a: bits 2.1 ** * * 1.9 *** **** 1.7 *** **** 1.5 *** **** Relative 1.3 *** **** Entropy 1.1 ******** (15.3 bits) 0.8 ******** 0.6 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel CTTGTCTG consensus C sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTTGTCTG MEME-2 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr1:100828658-100828738 47 1.38e-05 ccagtgccgt cttgtctg ctcctcactg chr6:28833632-28833712 65 1.38e-05 cttttattat cttgtctg gccccacc chr1:20204917-20204997 45 1.38e-05 ggcaggctat cttgtctg ctccttactg chr7:39761899-39761979 37 1.38e-05 actgcgccat cttgtctg ctccttactg chr7:16505552-16505632 24 1.38e-05 GACTTCATCA CTTGTCTG TGAGCCGACG chr6:37391719-37391799 28 1.38e-05 acagtgccat cttgtctg ctccttactg chr12:25086875-25086955 40 1.38e-05 ccggcaccag cttgtctg ctccttactg chrX:118925629-118925709 52 2.77e-05 CTTCTAGTGC CTTCTCTG TCTAGCGGTG chr16:8159629-8159709 47 2.77e-05 tcggtgccat cttctctg ctctttattg chr6:27286842-27286922 23 2.77e-05 CTATTTGCAG CTTCTCTG GACACATCAG -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTTGTCTG MEME-2 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr1:100828658-100828738 1.4e-05 46_[+2]_26 chr6:28833632-28833712 1.4e-05 64_[+2]_8 chr1:20204917-20204997 1.4e-05 44_[+2]_28 chr7:39761899-39761979 1.4e-05 36_[+2]_36 chr7:16505552-16505632 1.4e-05 23_[+2]_49 chr6:37391719-37391799 1.4e-05 27_[+2]_45 chr12:25086875-25086955 1.4e-05 39_[+2]_33 chrX:118925629-118925709 2.8e-05 51_[+2]_21 chr16:8159629-8159709 2.8e-05 46_[+2]_26 chr6:27286842-27286922 2.8e-05 22_[+2]_50 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTTGTCTG MEME-2 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF CTTGTCTG width=8 seqs=10 chr1:100828658-100828738 ( 47) CTTGTCTG 1 chr6:28833632-28833712 ( 65) CTTGTCTG 1 chr1:20204917-20204997 ( 45) CTTGTCTG 1 chr7:39761899-39761979 ( 37) CTTGTCTG 1 chr7:16505552-16505632 ( 24) CTTGTCTG 1 chr6:37391719-37391799 ( 28) CTTGTCTG 1 chr12:25086875-25086955 ( 40) CTTGTCTG 1 chrX:118925629-118925709 ( 52) CTTCTCTG 1 chr16:8159629-8159709 ( 47) CTTCTCTG 1 chr6:27286842-27286922 ( 23) CTTCTCTG 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTTGTCTG MEME-2 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 11.0846 E= 1.8e+002 -997 192 -997 -997 -997 -997 -997 211 -997 -997 -997 211 -997 18 142 -997 -997 -997 -997 211 -997 192 -997 -997 -997 -997 -997 211 -997 -997 193 -997 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTTGTCTG MEME-2 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 10 E= 1.8e+002 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.300000 0.700000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTTGTCTG MEME-2 regular expression -------------------------------------------------------------------------------- CTT[GC]TCTG -------------------------------------------------------------------------------- Time 8.49 secs. ******************************************************************************** ******************************************************************************** MOTIF TTWTTATG MEME-3 width = 8 sites = 10 llr = 103 E-value = 6.5e+002 ******************************************************************************** -------------------------------------------------------------------------------- Motif TTWTTATG MEME-3 Description -------------------------------------------------------------------------------- Simplified A ::5::a:2 pos.-specific C :::::::: probability G :::::::8 matrix T aa5aa:a: bits 2.1 ** **** 1.9 ** **** 1.7 ** **** 1.5 ** **** Relative 1.3 ** ***** Entropy 1.1 ******** (14.9 bits) 0.8 ******** 0.6 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel TTATTATG consensus T A sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTWTTATG MEME-3 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr6:95967199-95967279 67 9.89e-06 aatccaggga tttttatg gactca chr17:20771799-20771879 52 9.89e-06 agttcctgta tttttatg tggagttgct chr8:8702663-8702743 12 9.89e-06 TCAAGTGGAT TTTTTATG TTCTGCTTCA chr1:100828658-100828738 9 2.02e-05 ccctaatc ttattatg caaatggact chr16:8159629-8159709 9 2.02e-05 ccctaatc ttattatg caaaagagct chr1:20204917-20204997 11 2.02e-05 caccctaatc ttattatg caaataaatt chr7:39761899-39761979 1 2.02e-05 . ttattatg cagatgaatt chr12:25086875-25086955 2 2.02e-05 c ttattatg cacatgaatt chr6:27775685-27775765 45 2.95e-05 CGGTCTCCTC TTTTTATA TAATAGTTTA chr18:75705636-75705716 66 2.95e-05 gaaactcccg tttttata accatca -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTWTTATG MEME-3 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr6:95967199-95967279 9.9e-06 66_[+3]_6 chr17:20771799-20771879 9.9e-06 51_[+3]_21 chr8:8702663-8702743 9.9e-06 11_[+3]_61 chr1:100828658-100828738 2e-05 8_[+3]_64 chr16:8159629-8159709 2e-05 8_[+3]_64 chr1:20204917-20204997 2e-05 10_[+3]_62 chr7:39761899-39761979 2e-05 [+3]_72 chr12:25086875-25086955 2e-05 1_[+3]_71 chr6:27775685-27775765 2.9e-05 44_[+3]_28 chr18:75705636-75705716 2.9e-05 65_[+3]_7 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTWTTATG MEME-3 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF TTWTTATG width=8 seqs=10 chr6:95967199-95967279 ( 67) TTTTTATG 1 chr17:20771799-20771879 ( 52) TTTTTATG 1 chr8:8702663-8702743 ( 12) TTTTTATG 1 chr1:100828658-100828738 ( 9) TTATTATG 1 chr16:8159629-8159709 ( 9) TTATTATG 1 chr1:20204917-20204997 ( 11) TTATTATG 1 chr7:39761899-39761979 ( 1) TTATTATG 1 chr12:25086875-25086955 ( 2) TTATTATG 1 chr6:27775685-27775765 ( 45) TTTTTATA 1 chr18:75705636-75705716 ( 66) TTTTTATA 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTWTTATG MEME-3 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 11.7767 E= 6.5e+002 -997 -997 -997 211 -997 -997 -997 211 104 -997 -997 111 -997 -997 -997 211 -997 -997 -997 211 204 -997 -997 -997 -997 -997 -997 211 -28 -997 161 -997 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTWTTATG MEME-3 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 10 E= 6.5e+002 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.500000 0.000000 0.000000 0.500000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.200000 0.000000 0.800000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTWTTATG MEME-3 regular expression -------------------------------------------------------------------------------- TT[AT]TTAT[GA] -------------------------------------------------------------------------------- Time 12.14 secs. ******************************************************************************** ******************************************************************************** MOTIF TTMTAAAA MEME-4 width = 8 sites = 19 llr = 171 E-value = 2.2e+003 ******************************************************************************** -------------------------------------------------------------------------------- Motif TTMTAAAA MEME-4 Description -------------------------------------------------------------------------------- Simplified A ::5:a897 pos.-specific C ::3::::: probability G ::::::13 matrix T aa2a:2:: bits 2.1 ** ** 1.9 ** ** 1.7 ** ** 1.5 ** ** * Relative 1.3 ** ***** Entropy 1.1 ** ***** (13.0 bits) 0.8 ** ***** 0.6 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel TTATAAAA consensus C T G sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTMTAAAA MEME-4 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr10:17271197-17271277 47 1.06e-05 CCTAACGGGG TTATAAAA ACAGCGCCCT chr20:31220759-31220839 43 1.06e-05 gggaagctgc ttataaaa ccatcagatc chr22:35627034-35627114 41 1.06e-05 gaggagcccc ttataaaa ccatcagatc chr17:5522748-5522828 18 1.06e-05 gggaagcccc ttataaaa ccatcagatc chr10:70847795-70847875 36 2.21e-05 TTGGAACATT TTCTAAAA GGGACAGAGA chr14:56683750-56683830 49 2.21e-05 AGACTGTTGT TTCTAAAA ATAGATTTCC chr1:149858384-149858464 54 3.34e-05 CTAGGAAAGC TTATAAAG GCTTTCCTCT chr6:52529180-52529260 17 3.34e-05 AACTCGGACC TTATAAAG CGCGCCCGCT chr19:13953691-13953771 65 4.35e-05 GCCGAATCGC TTTTAAAA CCTTCCCG chr11:5526834-5526914 72 4.35e-05 caactccggt ttttaaaa c chr3:191143219-191143299 65 4.35e-05 gatctgatgg ttttaaaa atgggagc chr6:27835330-27835410 60 5.36e-05 GGCCCCGGGC TTATATAA GCCGGCGCTG chr11:57413253-57413333 37 6.60e-05 CAGACCCCTG TTCTAAAG GGTGCCTGGT chr15:93354038-93354118 70 6.60e-05 TGGAAAGAGT TTCTAAAG AAT chr12:6643611-6643691 40 7.70e-05 CGCCCCCGGT TTCTATAA ATTGAGCCCG chr4:37563264-37563344 45 7.70e-05 tgtagttatg ttctataa agtcacttca chr19:5434708-5434788 65 8.83e-05 cccagaccac ttataaga catgctga chr2:108972755-108972835 15 8.83e-05 taagtgccct ttataaga atcaacaagt chr6:26235179-26235259 62 1.10e-04 GGCTGAGGGT TTATATAG AGAGACGCTG -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTMTAAAA MEME-4 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr10:17271197-17271277 1.1e-05 46_[+4]_26 chr20:31220759-31220839 1.1e-05 42_[+4]_30 chr22:35627034-35627114 1.1e-05 40_[+4]_32 chr17:5522748-5522828 1.1e-05 17_[+4]_55 chr10:70847795-70847875 2.2e-05 35_[+4]_37 chr14:56683750-56683830 2.2e-05 48_[+4]_24 chr1:149858384-149858464 3.3e-05 53_[+4]_19 chr6:52529180-52529260 3.3e-05 16_[+4]_56 chr19:13953691-13953771 4.4e-05 64_[+4]_8 chr11:5526834-5526914 4.4e-05 71_[+4]_1 chr3:191143219-191143299 4.4e-05 64_[+4]_8 chr6:27835330-27835410 5.4e-05 59_[+4]_13 chr11:57413253-57413333 6.6e-05 36_[+4]_36 chr15:93354038-93354118 6.6e-05 69_[+4]_3 chr12:6643611-6643691 7.7e-05 39_[+4]_33 chr4:37563264-37563344 7.7e-05 44_[+4]_28 chr19:5434708-5434788 8.8e-05 64_[+4]_8 chr2:108972755-108972835 8.8e-05 14_[+4]_58 chr6:26235179-26235259 0.00011 61_[+4]_11 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTMTAAAA MEME-4 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF TTMTAAAA width=8 seqs=19 chr10:17271197-17271277 ( 47) TTATAAAA 1 chr20:31220759-31220839 ( 43) TTATAAAA 1 chr22:35627034-35627114 ( 41) TTATAAAA 1 chr17:5522748-5522828 ( 18) TTATAAAA 1 chr10:70847795-70847875 ( 36) TTCTAAAA 1 chr14:56683750-56683830 ( 49) TTCTAAAA 1 chr1:149858384-149858464 ( 54) TTATAAAG 1 chr6:52529180-52529260 ( 17) TTATAAAG 1 chr19:13953691-13953771 ( 65) TTTTAAAA 1 chr11:5526834-5526914 ( 72) TTTTAAAA 1 chr3:191143219-191143299 ( 65) TTTTAAAA 1 chr6:27835330-27835410 ( 60) TTATATAA 1 chr11:57413253-57413333 ( 37) TTCTAAAG 1 chr15:93354038-93354118 ( 70) TTCTAAAG 1 chr12:6643611-6643691 ( 40) TTCTATAA 1 chr4:37563264-37563344 ( 45) TTCTATAA 1 chr19:5434708-5434788 ( 65) TTATAAGA 1 chr2:108972755-108972835 ( 15) TTATAAGA 1 chr6:26235179-26235259 ( 62) TTATATAG 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTMTAAAA MEME-4 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 10.8043 E= 2.2e+003 -1089 -1089 -1089 211 -1089 -1089 -1089 211 112 26 -1089 -56 -1089 -1089 -1089 211 204 -1089 -1089 -1089 170 -1089 -1089 -14 188 -1089 -131 -1089 160 -1089 1 -1089 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTMTAAAA MEME-4 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 19 E= 2.2e+003 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.526316 0.315789 0.000000 0.157895 0.000000 0.000000 0.000000 1.000000 1.000000 0.000000 0.000000 0.000000 0.789474 0.000000 0.000000 0.210526 0.894737 0.000000 0.105263 0.000000 0.736842 0.000000 0.263158 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTMTAAAA MEME-4 regular expression -------------------------------------------------------------------------------- TT[AC]TA[AT]A[AG] -------------------------------------------------------------------------------- Time 15.79 secs. ******************************************************************************** ******************************************************************************** MOTIF TTACTGTA MEME-5 width = 8 sites = 7 llr = 75 E-value = 1.7e+004 ******************************************************************************** -------------------------------------------------------------------------------- Motif TTACTGTA MEME-5 Description -------------------------------------------------------------------------------- Simplified A ::7::::a pos.-specific C :::a:::: probability G ::3::a:: matrix T aa::a:a: bits 2.1 ** * ** 1.9 ** ***** 1.7 ** ***** 1.5 ** ***** Relative 1.3 ** ***** Entropy 1.1 ******** (15.5 bits) 0.8 ******** 0.6 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel TTACTGTA consensus G sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTACTGTA MEME-5 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr21:36260978-36261058 39 1.18e-05 GAACGTGCTT TTACTGTA AGCCCGGCCG chr1:20204917-20204997 57 1.18e-05 tgtctgctcc ttactgta cacgtggctg chr7:39761899-39761979 49 1.18e-05 tgtctgctcc ttactgta cgcgtgtctg chr6:37391719-37391799 40 1.18e-05 tgtctgctcc ttactgta cacgttgctg chr12:25086875-25086955 52 1.18e-05 tgtctgctcc ttactgta cacttggctg chr21:45158607-45158687 27 2.44e-05 gaaaccgcta ttgctgta gattacgcct chr12:68900650-68900730 16 2.44e-05 GGATGCTTAC TTGCTGTA CCAAACCCAT -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTACTGTA MEME-5 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr21:36260978-36261058 1.2e-05 38_[+5]_34 chr1:20204917-20204997 1.2e-05 56_[+5]_16 chr7:39761899-39761979 1.2e-05 48_[+5]_24 chr6:37391719-37391799 1.2e-05 39_[+5]_33 chr12:25086875-25086955 1.2e-05 51_[+5]_21 chr21:45158607-45158687 2.4e-05 26_[+5]_46 chr12:68900650-68900730 2.4e-05 15_[+5]_57 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTACTGTA MEME-5 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF TTACTGTA width=8 seqs=7 chr21:36260978-36261058 ( 39) TTACTGTA 1 chr1:20204917-20204997 ( 57) TTACTGTA 1 chr7:39761899-39761979 ( 49) TTACTGTA 1 chr6:37391719-37391799 ( 40) TTACTGTA 1 chr12:25086875-25086955 ( 52) TTACTGTA 1 chr21:45158607-45158687 ( 27) TTGCTGTA 1 chr12:68900650-68900730 ( 16) TTGCTGTA 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTACTGTA MEME-5 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 11.1915 E= 1.7e+004 -945 -945 -945 211 -945 -945 -945 211 156 -945 13 -945 -945 192 -945 -945 -945 -945 -945 211 -945 -945 193 -945 -945 -945 -945 211 204 -945 -945 -945 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTACTGTA MEME-5 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 7 E= 1.7e+004 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.714286 0.000000 0.285714 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 1.000000 1.000000 0.000000 0.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTACTGTA MEME-5 regular expression -------------------------------------------------------------------------------- TT[AG]CTGTA -------------------------------------------------------------------------------- Time 19.40 secs. ******************************************************************************** ******************************************************************************** SUMMARY OF MOTIFS ******************************************************************************** -------------------------------------------------------------------------------- Combined block diagrams: non-overlapping sites with p-value < 0.0001 -------------------------------------------------------------------------------- SEQUENCE NAME COMBINED P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr5:78884599-78884679 8.45e-01 80 chr19:5352468-5352548 4.57e-01 80 chr1:167523628-167523708 3.70e-01 80 chr12:122908420-12290850 6.26e-01 80 chr8:49959358-49959438 2.10e-01 80 chr11:66635988-66636068 3.82e-02 80 chr18:9014262-9014342 5.08e-01 80 chr3:69128567-69128647 1.54e-01 80 chr14:75413235-75413315 7.40e-01 80 chr15:82246923-82247003 3.38e-01 80 chr5:61561552-61561632 7.19e-02 80 chr11:2398495-2398575 9.70e-01 80 chr14:56683750-56683830 1.36e-02 48_[+4(2.21e-05)]_24 chr19:10949226-10949306 6.88e-01 80 chr7:103020197-103020277 7.57e-03 15_[+1(3.60e-05)]_57 chr5:16528537-16528617 2.60e-01 80 chr15:96679024-96679104 4.50e-01 80 chr12:25086875-25086955 2.88e-06 1_[+3(2.02e-05)]_30_[+2(1.38e-05)]_\ 4_[+5(1.18e-05)]_21 chr17:26421264-26421344 4.35e-01 80 chr6:29782909-29782989 1.80e-01 80 chr19:17516358-17516438 6.42e-01 80 chr1:37791761-37791841 8.91e-01 80 chr12:50615369-50615449 3.49e-01 80 chrX:118824868-118824948 2.00e-01 80 chr17:10694432-10694512 3.65e-02 80 chr17:42147485-42147565 3.90e-02 80 chr11:61266567-61266647 1.50e-01 80 chr1:211779873-211779953 9.41e-01 80 chr6:119031241-119031321 8.50e-01 80 chr5:132002088-132002168 1.95e-01 80 chr11:1372886-1372966 8.15e-01 80 chr18:74587476-74587556 6.48e-01 80 chr2:108972755-108972835 5.91e-03 14_[+4(8.83e-05)]_37_[+3(8.03e-05)]_\ 13 chr14:23120280-23120360 4.72e-01 80 chr3:112360073-112360153 2.34e-03 57_[+1(3.60e-05)]_15 chr13:45266412-45266492 2.63e-02 14_[+1(8.99e-05)]_58 chr1:46503148-46503228 8.05e-02 29_[+1(1.87e-05)]_43 chr2:191137236-191137316 8.12e-01 80 chr19:1727559-1727639 4.91e-01 80 chr10:70847795-70847875 3.23e-02 35_[+4(2.21e-05)]_37 chr17:15083698-15083778 5.41e-02 9_[+1(5.49e-05)]_63 chr12:9517051-9517131 4.49e-02 80 chr6:37391719-37391799 3.42e-04 27_[+2(1.38e-05)]_4_[+5(1.18e-05)]_\ 33 chr2:20646769-20646849 2.21e-01 80 chr12:33137043-33137123 6.94e-02 80 chr6:7723986-7724066 2.31e-01 80 chr1:25215118-25215198 2.49e-01 80 chr19:55686220-55686300 7.92e-01 80 chr16:9085899-9085979 9.98e-01 80 chr5:81574452-81574532 2.35e-01 64_[+1(3.60e-05)]_8 chr20:52369809-52369889 3.05e-01 80 chr19:8226086-8226166 2.78e-01 80 chr6:28688243-28688323 7.59e-01 80 chr4:38325046-38325126 4.36e-01 80 chr16:88851547-88851627 9.79e-01 80 chr5:173615547-173615627 8.39e-01 80 chr13:30756449-30756529 8.80e-01 80 chrX:153191117-153191197 8.72e-01 80 chr14:57476681-57476761 7.08e-01 80 chr17:76275870-76275950 2.77e-01 80 chr10:23344768-23344848 8.64e-02 80 chr11:122932805-12293288 7.20e-01 80 chr9:130186345-130186425 8.13e-01 80 chr17:45253894-45253974 2.23e-01 80 chr22:30627085-30627165 5.94e-01 80 chr2:220549748-220549828 8.36e-01 80 chr17:6843680-6843760 7.47e-03 80 chr1:167906744-167906824 9.60e-01 80 chr15:75052989-75053069 3.04e-01 80 chr1:42344258-42344338 2.88e-01 80 chr1:207779174-207779254 7.34e-01 80 chr7:39761696-39761776 6.42e-03 80 chr5:170814778-170814858 5.32e-01 80 chr14:102176553-10217663 1.52e-03 80 chr5:118753813-118753893 9.48e-02 80 chr11:120107294-12010737 4.01e-01 80 chr22:50555772-50555852 1.19e-01 80 chr17:17255710-17255790 2.80e-01 63_[+1(5.49e-05)]_9 chr14:91016440-91016520 9.57e-01 80 chr7:16505552-16505632 5.52e-03 23_[+2(1.38e-05)]_49 chr3:71113081-71113161 5.93e-02 6_[+1(1.87e-05)]_66 chr14:34420262-34420342 9.01e-01 80 chr1:236451499-236451579 3.03e-01 80 chr4:989698-989778 9.98e-01 80 chr11:117997196-11799727 4.98e-01 80 chr18:75705636-75705716 2.46e-03 65_[+3(2.95e-05)]_7 chr1:149859691-149859771 5.76e-02 80 chr16:27210269-27210349 3.44e-01 80 chr11:66491255-66491335 7.45e-01 80 chr17:56743998-56744078 6.48e-02 80 chr2:188419191-188419271 1.07e-01 80 chr17:5522748-5522828 2.80e-02 17_[+4(1.06e-05)]_55 chr3:129118765-129118845 1.59e-01 80 chr1:200610189-200610269 4.50e-01 80 chr12:21810761-21810841 5.17e-02 17_[+1(1.87e-05)]_55 chr10:70320040-70320120 7.24e-01 80 chr17:80326294-80326374 7.72e-02 80 chr1:160696102-160696182 1.73e-01 80 chr7:39761899-39761979 4.20e-06 [+3(2.02e-05)]_28_[+2(1.38e-05)]_4_\ [+5(1.18e-05)]_24 chrX:135838776-135838856 6.08e-01 80 chr2:30884126-30884206 7.03e-01 80 chr14:35836740-35836820 5.01e-01 80 chr22:29548874-29548954 7.32e-02 80 chr2:61763848-61763928 3.59e-02 80 chr11:61129304-61129384 9.73e-01 80 chr16:57717016-57717096 2.01e-01 3_[+1(1.87e-05)]_3_[+1(5.49e-05)]_\ 58 chr7:2913701-2913781 7.38e-02 80 chr4:31998995-31999075 2.75e-01 80 chr6:27833024-27833104 1.12e-01 80 chr19:48948710-48948790 8.30e-01 80 chr1:20204917-20204997 4.00e-06 10_[+3(2.02e-05)]_26_[+2(1.38e-05)]_\ 4_[+5(1.18e-05)]_16 chr8:8702663-8702743 1.87e-02 11_[+3(9.89e-06)]_61 chr17:27188961-27189041 2.24e-02 80 chr6:27286842-27286922 3.69e-02 22_[+2(2.77e-05)]_50 chr6:56884316-56884396 6.46e-02 80 chr6:43738356-43738436 9.69e-01 80 chr17:39684604-39684684 4.78e-01 80 chr17:41953268-41953348 9.92e-01 80 chr7:133896172-133896252 4.34e-02 80 chr12:102071964-10207204 1.71e-01 80 chr1:149215265-149215345 9.97e-01 80 chr3:101568296-101568376 9.31e-01 80 chr22:38053895-38053975 9.25e-01 80 chr4:83668203-83668283 9.93e-01 80 chrX:41193353-41193433 9.49e-01 80 chr6:28833632-28833712 3.19e-04 64_[+2(1.38e-05)]_8 chr19:45971241-45971321 4.27e-01 80 chr21:40277685-40277765 1.61e-01 80 chr16:8159629-8159709 4.96e-05 8_[+3(2.02e-05)]_30_[+2(2.77e-05)]_\ 26 chr12:68900650-68900730 9.10e-03 15_[+5(2.44e-05)]_57 chr3:156805710-156805790 5.22e-01 80 chr12:8088730-8088810 8.33e-02 80 chr17:78992117-78992197 1.83e-01 80 chr12:113772877-11377295 8.98e-01 80 chr3:49449599-49449679 5.74e-02 80 chr4:37563264-37563344 2.87e-03 44_[+4(7.70e-05)]_28 chr3:24537171-24537251 4.97e-01 80 chr3:60263269-60263349 1.06e-02 4_[+1(7.23e-05)]_68 chr6:27835330-27835410 4.48e-02 59_[+4(5.36e-05)]_13 chr14:73374655-73374735 2.68e-01 80 chr9:137098192-137098272 6.23e-01 80 chr7:120627931-120628011 4.48e-01 80 chr11:10476634-10476714 9.04e-01 80 chr6:37465100-37465180 2.93e-01 80 chr6:27775685-27775765 1.71e-03 44_[+3(2.95e-05)]_28 chr3:191143219-191143299 6.59e-02 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