******************************************************************************** MEME - Motif discovery tool ******************************************************************************** MEME version 5.3.3 (Release date: Sun Feb 7 15:39:52 2021 -0800) For further information on how to interpret these results please access https://meme-suite.org/meme. To get a copy of the MEME Suite software please access https://meme-suite.org. ******************************************************************************** ******************************************************************************** REFERENCE ******************************************************************************** If you use this program in your research, please cite: Timothy L. Bailey and Charles Elkan, "Fitting a mixture model by expectation maximization to discover motifs in biopolymers", Proceedings of the Second International Conference on Intelligent Systems for Molecular Biology, pp. 28-36, AAAI Press, Menlo Park, California, 1994. ******************************************************************************** ******************************************************************************** TRAINING SET ******************************************************************************** PRIMARY SEQUENCES= ../result/final_prediction/K562/fasta/RankLinear0.6_40/GMEB1.fasta CONTROL SEQUENCES= --none-- ALPHABET= ACGT Sequence name Weight Length Sequence name Weight Length ------------- ------ ------ ------------- ------ ------ chrX:148622419-148622499 1.0000 80 chr18:77748583-77748663 1.0000 80 chrX:133507260-133507340 1.0000 80 chr7:50518067-50518147 1.0000 80 chr13:28024308-28024388 1.0000 80 chr2:73053165-73053245 1.0000 80 chrX:149106763-149106843 1.0000 80 chr9:80850891-80850971 1.0000 80 chr17:47755419-47755499 1.0000 80 chr19:38085654-38085734 1.0000 80 chr8:2075753-2075833 1.0000 80 chr3:80819747-80819827 1.0000 80 chr19:57874707-57874787 1.0000 80 chr22:25844006-25844086 1.0000 80 chr6:169852554-169852634 1.0000 80 chr7:74508839-74508919 1.0000 80 chr12:44152604-44152684 1.0000 80 chr2:227700740-227700820 1.0000 80 chr19:58361126-58361206 1.0000 80 chr17:80606306-80606386 1.0000 80 chr13:21872186-21872266 1.0000 80 chrX:30265136-30265216 1.0000 80 chr6:121655728-121655808 1.0000 80 chr15:29561992-29562072 1.0000 80 chr19:36705593-36705673 1.0000 80 chr1:155243286-155243366 1.0000 80 chr16:30389138-30389218 1.0000 80 chr10:119135074-11913515 1.0000 80 chr16:27214789-27214869 1.0000 80 chr19:36390677-36390757 1.0000 80 chr14:52456109-52456189 1.0000 80 chr4:148605347-148605427 1.0000 80 chr19:50169126-50169206 1.0000 80 chr3:46064576-46064656 1.0000 80 chr2:74648817-74648897 1.0000 80 chr2:48667785-48667865 1.0000 80 chr7:66057324-66057404 1.0000 80 chr15:31618619-31618699 1.0000 80 chr2:109403153-109403233 1.0000 80 chr20:56964204-56964284 1.0000 80 chr19:45972472-45972552 1.0000 80 chr2:219433025-219433105 1.0000 80 chr11:105948360-10594844 1.0000 80 chr6:79788202-79788282 1.0000 80 chr2:99953729-99953809 1.0000 80 chr4:6711630-6711710 1.0000 80 chr18:47013615-47013695 1.0000 80 chr17:40610843-40610923 1.0000 80 chr14:96968633-96968713 1.0000 80 chr6:33539149-33539229 1.0000 80 chr17:18684513-18684593 1.0000 80 chr5:43121561-43121641 1.0000 80 chr5:139487350-139487430 1.0000 80 chr11:102980078-10298015 1.0000 80 chr17:58603558-58603638 1.0000 80 chr5:140943864-140943944 1.0000 80 chr14:64108734-64108814 1.0000 80 chr11:6255902-6255982 1.0000 80 chr20:61493507-61493587 1.0000 80 chr13:20207714-20207794 1.0000 80 chr16:47007567-47007647 1.0000 80 chr20:43150683-43150763 1.0000 80 chr12:50677435-50677515 1.0000 80 chr17:43568069-43568149 1.0000 80 chr8:17104326-17104406 1.0000 80 chr11:134582244-13458232 1.0000 80 chr5:89825379-89825459 1.0000 80 chr15:82555045-82555125 1.0000 80 chr17:62833239-62833319 1.0000 80 chr7:38217751-38217831 1.0000 80 chr14:75760897-75760977 1.0000 80 chr20:3451470-3451550 1.0000 80 chr19:33071845-33071925 1.0000 80 chr19:46088108-46088188 1.0000 80 chr17:61904497-61904577 1.0000 80 chr4:140005388-140005468 1.0000 80 chr7:39989159-39989239 1.0000 80 chr1:40840244-40840324 1.0000 80 chrX:152110117-152110197 1.0000 80 chr5:87564687-87564767 1.0000 80 chr11:78285804-78285884 1.0000 80 chr11:43333463-43333543 1.0000 80 chr15:41099755-41099835 1.0000 80 chr1:113615791-113615871 1.0000 80 chr2:68479851-68479931 1.0000 80 chr3:80819488-80819568 1.0000 80 chr22:43539413-43539493 1.0000 80 chrX:48334470-48334550 1.0000 80 chr1:86861728-86861808 1.0000 80 chr18:77439666-77439746 1.0000 80 chr3:49761424-49761504 1.0000 80 chr14:60558651-60558731 1.0000 80 chr4:24586165-24586245 1.0000 80 chr6:70506953-70507033 1.0000 80 chr7:1015111-1015191 1.0000 80 chr5:86708718-86708798 1.0000 80 chr13:27825405-27825485 1.0000 80 chr19:55987880-55987960 1.0000 80 chr19:38183209-38183289 1.0000 80 chr7:76178611-76178691 1.0000 80 chr6:168813819-168813899 1.0000 80 chr14:50779043-50779123 1.0000 80 chr16:475447-475527 1.0000 80 chr4:187125364-187125444 1.0000 80 chr5:112849337-112849417 1.0000 80 chr2:44001109-44001189 1.0000 80 chr19:40336962-40337042 1.0000 80 chr14:105195773-10519585 1.0000 80 chr16:20911827-20911907 1.0000 80 chr14:93260436-93260516 1.0000 80 chrX:47341959-47342039 1.0000 80 chrX:106916332-106916412 1.0000 80 chr4:175041681-175041761 1.0000 80 chr7:72349868-72349948 1.0000 80 chrX:119763997-119764077 1.0000 80 chr20:55904825-55904905 1.0000 80 chr19:57999011-57999091 1.0000 80 chr9:34178954-34179034 1.0000 80 chr4:187422081-187422161 1.0000 80 chr22:41809988-41810068 1.0000 80 chr13:25875670-25875750 1.0000 80 chr19:42463524-42463604 1.0000 80 chr20:5100582-5100662 1.0000 80 chr5:133304303-133304383 1.0000 80 chr20:1373776-1373856 1.0000 80 chr8:2075406-2075486 1.0000 80 chr10:93683498-93683578 1.0000 80 chr6:146285433-146285513 1.0000 80 chr1:22379139-22379219 1.0000 80 chr20:42219457-42219537 1.0000 80 chr16:4526351-4526431 1.0000 80 chr12:94853750-94853830 1.0000 80 chr7:98741896-98741976 1.0000 80 chr22:42017228-42017308 1.0000 80 chr5:52095909-52095989 1.0000 80 chr13:24463561-24463641 1.0000 80 chr7:56119320-56119400 1.0000 80 chr9:139010691-139010771 1.0000 80 chr3:52719983-52720063 1.0000 80 chr22:30162950-30163030 1.0000 80 chr6:38607810-38607890 1.0000 80 chr1:2343995-2344075 1.0000 80 chr8:59323840-59323920 1.0000 80 chr4:170541627-170541707 1.0000 80 chr2:26256937-26257017 1.0000 80 chr1:115053864-115053944 1.0000 80 chr17:73178987-73179067 1.0000 80 chr16:30569679-30569759 1.0000 80 chr14:45722437-45722517 1.0000 80 chrX:41193277-41193357 1.0000 80 chr13:48612057-48612137 1.0000 80 chr11:120894733-12089481 1.0000 80 chr4:169931452-169931532 1.0000 80 chr15:76629069-76629149 1.0000 80 chr19:18451195-18451275 1.0000 80 chr17:78120961-78121041 1.0000 80 chr5:93447362-93447442 1.0000 80 chr19:58446766-58446846 1.0000 80 chrX:15693619-15693699 1.0000 80 chr19:57901157-57901237 1.0000 80 chr11:82904662-82904742 1.0000 80 chr4:130014718-130014798 1.0000 80 chr6:146136059-146136139 1.0000 80 chr4:2538121-2538201 1.0000 80 chr19:17008523-17008603 1.0000 80 chr17:4890901-4890981 1.0000 80 chr12:57824834-57824914 1.0000 80 chr19:58427978-58428058 1.0000 80 chr11:28129728-28129808 1.0000 80 chr19:52207495-52207575 1.0000 80 chr3:93698941-93699021 1.0000 80 chr16:67217796-67217876 1.0000 80 chr15:68346389-68346469 1.0000 80 chr17:76250661-76250741 1.0000 80 chr2:200775951-200776031 1.0000 80 chr13:32889533-32889613 1.0000 80 chr19:1241639-1241719 1.0000 80 chr11:112097145-11209722 1.0000 80 chr6:117996507-117996587 1.0000 80 chr17:2615147-2615227 1.0000 80 chr19:1205637-1205717 1.0000 80 chrX:55026680-55026760 1.0000 80 chr18:9102625-9102705 1.0000 80 chrX:40440077-40440157 1.0000 80 chr10:104159374-10415945 1.0000 80 chr6:105307751-105307831 1.0000 80 chr7:66205567-66205647 1.0000 80 chr3:10183471-10183551 1.0000 80 chr17:42144053-42144133 1.0000 80 chr2:30670112-30670192 1.0000 80 chr9:101984299-101984379 1.0000 80 chr11:57435219-57435299 1.0000 80 chr11:129765327-12976540 1.0000 80 chr19:2841083-2841163 1.0000 80 chr16:31119647-31119727 1.0000 80 chr12:64616039-64616119 1.0000 80 chr10:2357320-2357400 1.0000 80 chr3:49711215-49711295 1.0000 80 chr17:15902960-15903040 1.0000 80 chr19:12917280-12917360 1.0000 80 chr14:50329577-50329657 1.0000 80 chr3:81810612-81810692 1.0000 80 chr5:157286130-157286210 1.0000 80 chr16:838717-838797 1.0000 80 chr11:134123311-13412339 1.0000 80 chr15:72766564-72766644 1.0000 80 chrX:119384639-119384719 1.0000 80 chr14:65569231-65569311 1.0000 80 chr19:19887277-19887357 1.0000 80 chr19:12893310-12893390 1.0000 80 chr7:17980089-17980169 1.0000 80 chr9:139760791-139760871 1.0000 80 chr13:73301846-73301926 1.0000 80 chr15:41709073-41709153 1.0000 80 chr8:135724884-135724964 1.0000 80 chr4:100485118-100485198 1.0000 80 chr12:57081999-57082079 1.0000 80 chr17:18086358-18086438 1.0000 80 chr17:1619547-1619627 1.0000 80 chr7:102004265-102004345 1.0000 80 chr3:122102957-122103037 1.0000 80 chr10:120840414-12084049 1.0000 80 chr16:2802506-2802586 1.0000 80 chr13:28024541-28024621 1.0000 80 chr4:90032687-90032767 1.0000 80 chr8:101734401-101734481 1.0000 80 chr2:128568695-128568775 1.0000 80 chr9:7799779-7799859 1.0000 80 chr10:27444194-27444274 1.0000 80 chr6:101329203-101329283 1.0000 80 chr3:156544018-156544098 1.0000 80 chrX:48755057-48755137 1.0000 80 chr2:32288546-32288626 1.0000 80 chr9:99616857-99616937 1.0000 80 chr9:37422609-37422689 1.0000 80 chr12:121837786-12183786 1.0000 80 chr19:58919880-58919960 1.0000 80 chr19:52552087-52552167 1.0000 80 chr5:76326128-76326208 1.0000 80 chr19:2163667-2163747 1.0000 80 chr1:17338480-17338560 1.0000 80 chr6:30294952-30295032 1.0000 80 chr5:154238083-154238163 1.0000 80 chr21:46859277-46859357 1.0000 80 chr20:37377012-37377092 1.0000 80 chr21:38446137-38446217 1.0000 80 chr5:1799970-1800050 1.0000 80 chr10:13203477-13203557 1.0000 80 chr6:74171438-74171518 1.0000 80 chr20:20693560-20693640 1.0000 80 ******************************************************************************** ******************************************************************************** COMMAND LINE SUMMARY ******************************************************************************** This information can also be useful in the event you wish to report a problem with the MEME software. command: meme -oc ../result/final_prediction/K562/inference_raw/MEME/RankLinear0.6_40_GMEB1/ -dna -nmotifs 5 -w 8 -maxsize 250000 -nostatus ../result/final_prediction/K562/fasta/RankLinear0.6_40/GMEB1.fasta model: mod= zoops nmotifs= 5 evt= inf objective function: em= E-value of product of p-values starts= E-value of product of p-values strands: + width: minw= 8 maxw= 8 nsites: minsites= 2 maxsites= 250 wnsites= 0.8 theta: spmap= uni spfuzz= 0.5 em: prior= dirichlet b= 0.01 maxiter= 50 distance= 1e-05 trim: wg= 11 ws= 1 endgaps= yes data: n= 20000 N= 250 sample: seed= 0 hsfrac= 0 searchsize= 20000 norand= no csites= 1000 Letter frequencies in dataset: A 0.158 C 0.334 G 0.343 T 0.165 Background letter frequencies (from file dataset with add-one prior applied): A 0.158 C 0.334 G 0.343 T 0.165 Background model order: 0 ******************************************************************************** ******************************************************************************** MOTIF CGTGCGTS MEME-1 width = 8 sites = 89 llr = 655 E-value = 2.0e-028 ******************************************************************************** -------------------------------------------------------------------------------- Motif CGTGCGTS MEME-1 Description -------------------------------------------------------------------------------- Simplified A 1::1:::: pos.-specific C 81::a:13 probability G :7:9:a:6 matrix T 11a:::9: bits 2.7 * 2.4 * 2.1 * * 1.9 * * Relative 1.6 * *** Entropy 1.3 ***** (10.6 bits) 1.1 ***** 0.8 * ***** 0.5 ******* 0.3 ******** 0.0 -------- Multilevel CGTGCGTG consensus C sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CGTGCGTS MEME-1 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr7:102004265-102004345 33 4.20e-05 CGTGTTCGCG CGTGCGTG CTTGCACATG chr12:57081999-57082079 40 4.20e-05 GGAGAATGAA CGTGCGTG CGTGCAAACG chr19:12893310-12893390 48 4.20e-05 GCGCGTGCGT CGTGCGTG ACGTGAGACA chr12:64616039-64616119 61 4.20e-05 TGCGCACAAG CGTGCGTG CGCGTGACCG chr19:57901157-57901237 41 4.20e-05 GGGACGTTTG CGTGCGTG CGCACCGTCG chr17:78120961-78121041 11 4.20e-05 AAGCGAGAGA cgtgcgtg cgtacgtgcg chr13:48612057-48612137 59 4.20e-05 TTCCGTGTGC CGTGCGTG AGAACGTCCG chr9:139010691-139010771 36 4.20e-05 tgcgtgcgtg cgtgcgtg cgCACGCTGC chr7:72349868-72349948 28 4.20e-05 CGTGTTCGCG CGTGCGTG CTCGCACATG chr4:175041681-175041761 71 4.20e-05 tgtgtgcgtg cgtgcgtg tg chrX:106916332-106916412 40 4.20e-05 tgcgtgcgtg cgtgcgtg tgtgtgtgtg chrX:47341959-47342039 38 4.20e-05 CGCGCCGGTG CGTGCGTG CGCGTGCGCG chr7:76178611-76178691 7 4.20e-05 TTCGCG CGTGCGTG CTCGCACATG chr4:24586165-24586245 45 4.20e-05 gcttccgcag cgtgcgtg cgtgcgagtg chr1:40840244-40840324 16 4.20e-05 tgcgtgcgtg cgtgcgtg cgtgtgtgtg chr20:61493507-61493587 1 4.20e-05 . CGTGCGTG CACGTGCGCC chr14:96968633-96968713 61 4.20e-05 GCACGCACGG CGTGCGTG GTGGCGTCAG chr20:56964204-56964284 70 4.20e-05 tgcgtgcgtg cgtgcgtg cgt chr2:109403153-109403233 13 4.20e-05 TCCCTGCCGC CGTGCGTG CCTCGGGGGG chr17:80606306-80606386 67 4.20e-05 gacgtgcgtg cgtgcgtg ctggac chr2:227700740-227700820 5 4.20e-05 GGAA CGTGCGTG ATGACGCACG chr6:169852554-169852634 52 4.20e-05 AGAGAGGAGC CGTGCGTG GGGTCAGAGA chr22:25844006-25844086 47 4.20e-05 gcgtgcgtgg cgtgcgtg gcgtggAGTC chr19:57874707-57874787 35 4.20e-05 tgcgtgcgtg cgtgcgtg cgtgcgtccg chr13:28024308-28024388 32 4.20e-05 GTACTGCGTG CGTGCGTG CGCACAAACG chr7:50518067-50518147 51 4.20e-05 tgagtgcgtg cgtgcgtg cgtTCGGCGC chr18:77748583-77748663 1 4.20e-05 . CGTGCGTG CTGACGGCAT chrX:148622419-148622499 58 4.20e-05 CTCCCGCGTA CGTGCGTG GTGTGCATAC chr10:13203477-13203557 44 8.30e-05 CCCACAGCCG CGTGCGTC TGACGTCAAG chrX:55026680-55026760 35 8.30e-05 CCCCGCCCGA CGTGCGTC AGGCGCTTTA chr14:45722437-45722517 47 8.30e-05 ATTGCGCCAC CGTGCGTC TCACAGGGAC chr2:26256937-26257017 11 8.30e-05 TACGCCCTTG CGTGCGTC TCAGGCAGCG chr19:46088108-46088188 4 8.30e-05 ATG CGTGCGTC AGTACGTATG chr2:74648817-74648897 47 8.30e-05 GCCGTGCGTA CGTGCGTC GTCTCTATGG chr3:80819747-80819827 36 8.30e-05 CTCCTCTTAA CGTGCGTC TGCACAGCTG chr19:38085654-38085734 9 8.30e-05 ACAAGCTC CGTGCGTC AAGACATAAC chr2:68479851-68479931 8 1.03e-04 GCCGCCC CTTGCGTG CAGGGTGGGG chr6:33539149-33539229 34 1.03e-04 GAAGGGCACG CTTGCGTG CTCGCGGCGG chr10:93683498-93683578 32 1.24e-04 GACGCTCAGT TGTGCGTG CCGACGCCCG chr7:74508839-74508919 4 1.24e-04 GGG TGTGCGTG ATGCCACGCT chrX:133507260-133507340 59 1.24e-04 CTGTGGGTCG TGTGCGTG CGAGGGGGGC chr9:99616857-99616937 31 1.44e-04 CCCATAAGCT CTTGCGTC CGCCTTCGAC chr17:42144053-42144133 1 1.44e-04 . CTTGCGTC ACACGCCGGG chr4:130014718-130014798 42 1.44e-04 GGTGGCGCCT CTTGCGTC ATCACGCGGG chr18:47013615-47013695 64 1.44e-04 CAAAGGCGCG CTTGCGTC AACCCGGGG chr15:29561992-29562072 60 1.44e-04 AAGCCTGCGC CTTGCGTC AGGGCGGCTG chr2:73053165-73053245 23 1.44e-04 GACACGCCCC CTTGCGTC ACCGCGTCCG chr19:18451195-18451275 21 1.64e-04 CACCTGGCTC AGTGCGTG CAAGCGGCTA chr3:52719983-52720063 39 1.64e-04 CGGCAGCGTA AGTGCGTG ACGCTCGTCA chrX:48334470-48334550 14 1.64e-04 GCAGCCACGC AGTGCGTG GATTCAGCCG chr10:2357320-2357400 57 1.84e-04 CCCGGCGTGC TGTGCGTC CCCTCCGGAA chr5:43121561-43121641 59 1.84e-04 GCGGTGACGG TGTGCGTC GACGTAAGTG chr20:1373776-1373856 1 2.44e-04 . CCTGCGTG CGCGCCCCAC chr3:49761424-49761504 15 2.44e-04 TCGGCTGCCG CGTACGTG GCACGGCCGC chr3:80819488-80819568 59 2.44e-04 CTCCTCTCAA CGTACGTG CGCTCCTCTC chr9:80850891-80850971 35 2.44e-04 GGAGGCGGGA CCTGCGTG CCGACGCACA chr13:25875670-25875750 69 2.54e-04 CGGGCGTACT TTTGCGTG GTTG chr11:102980078-10298015 3 2.54e-04 GC TTTGCGTG CGCGTGCCCC chr11:57435219-57435299 26 2.73e-04 CGTCTTCTCG CGTGCGTA CGTCGTTGTG chr19:45972472-45972552 19 2.73e-04 ACGGGGGACC CGTGCGTA ACGGCTGACG chr6:121655728-121655808 4 2.93e-04 GCC AGTGCGTC ATTTCGGAAA chr3:122102957-122103037 58 3.61e-04 cccggcgccg ccTGCGTC CTTCCCACTC chr16:67217796-67217876 66 3.61e-04 TCGCCGATGA CGTACGTC CTCGGGC chr22:30162950-30163030 24 3.61e-04 GGCTCCTCCT CCTGCGTC CTCGCGTCGC chr2:99953729-99953809 70 3.61e-04 TGAGCCGCGC CCTGCGTC CTC chr1:155243286-155243366 20 3.61e-04 GGACCGACGT CCTGCGTC GCTTCCCAGC chr7:17980089-17980169 50 4.10e-04 CTCGCTGCAA CGTGCGTT CCCATTGGCG chr22:42017228-42017308 19 4.10e-04 ATAGTGCGCA CATGCGTG ATGACGTAGA chr19:55987880-55987960 71 4.10e-04 ACTCGGAGTA CGTGCGTT GT chr11:105948360-10594844 26 4.10e-04 TGGGGCCACG TTTGCGTC CGCGCCATCA chr2:32288546-32288626 68 5.05e-04 CACGGGAAGA CGTGCGCG TGCGC chr17:76250661-76250741 31 5.05e-04 TCGCGGCGGG CGTGCGCG AGCGTCTGCG chr19:52207495-52207575 11 5.05e-04 GCCTGGCTGA CGTGCGCG CCCCCGCAGT chr11:43333463-43333543 35 5.05e-04 CCGCTCCCGA CGTGCGCG TCTTTACGTA chrX:152110117-152110197 9 5.05e-04 ACGCGACG CGTGCGCG CCTGTGCACC chrX:41193277-41193357 73 5.35e-04 GGGCACACGT TGTACGTG chr1:2343995-2344075 32 5.35e-04 ACGACGTGGC TCTGCGTG CGGCGCAGAC chr6:168813819-168813899 26 5.35e-04 GGCGGGAGCG TGTACGTG AGCGCGGCGG chr13:32889533-32889613 33 5.96e-04 ACTTCCGGGT GGTGCGTG TGCTGCGTGT chr1:22379139-22379219 26 5.96e-04 GCTGACGTCA GGTGCGTG CCCCTGTCCG chr15:31618619-31618699 59 6.25e-04 CCCCGGACGT CATGCGTC AGCGCGCCCC chr6:117996507-117996587 33 7.55e-04 AGTTCGCAGG CGTGCGCC TTCCCTCACT chr19:1241639-1241719 52 7.55e-04 GTCAACGTCG CGTGCGCC CTGCCGGGAG chrX:119763997-119764077 46 7.55e-04 CTGCGCGCAC ACTGCGTG CCCTTTCTCC chr14:52456109-52456189 26 7.55e-04 TGAGCGTCGA CGTGCGCC GACGTGGCCC chr8:59323840-59323920 11 8.63e-04 GCGCACGCAC CTTGCGCG TCTTCGCCCC chr5:52095909-52095989 37 1.01e-03 TCAGCCCGCT GTTGCGTG CTGCCAGCGG chr14:64108734-64108814 29 1.01e-03 GTAGACCCAG CGTACGTA CAACGCTCAC chr16:27214789-27214869 22 1.04e-03 TCCTCCAGGC ACTGCGTC GTGATCAGAC -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CGTGCGTS MEME-1 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr7:102004265-102004345 4.2e-05 32_[+1]_40 chr12:57081999-57082079 4.2e-05 39_[+1]_33 chr19:12893310-12893390 4.2e-05 47_[+1]_25 chr12:64616039-64616119 4.2e-05 60_[+1]_12 chr19:57901157-57901237 4.2e-05 40_[+1]_32 chr17:78120961-78121041 4.2e-05 10_[+1]_62 chr13:48612057-48612137 4.2e-05 58_[+1]_14 chr9:139010691-139010771 4.2e-05 35_[+1]_37 chr7:72349868-72349948 4.2e-05 27_[+1]_45 chr4:175041681-175041761 4.2e-05 70_[+1]_2 chrX:106916332-106916412 4.2e-05 39_[+1]_33 chrX:47341959-47342039 4.2e-05 37_[+1]_35 chr7:76178611-76178691 4.2e-05 6_[+1]_66 chr4:24586165-24586245 4.2e-05 44_[+1]_28 chr1:40840244-40840324 4.2e-05 15_[+1]_57 chr20:61493507-61493587 4.2e-05 [+1]_72 chr14:96968633-96968713 4.2e-05 60_[+1]_12 chr20:56964204-56964284 4.2e-05 69_[+1]_3 chr2:109403153-109403233 4.2e-05 12_[+1]_60 chr17:80606306-80606386 4.2e-05 66_[+1]_6 chr2:227700740-227700820 4.2e-05 4_[+1]_68 chr6:169852554-169852634 4.2e-05 51_[+1]_21 chr22:25844006-25844086 4.2e-05 46_[+1]_26 chr19:57874707-57874787 4.2e-05 34_[+1]_38 chr13:28024308-28024388 4.2e-05 31_[+1]_41 chr7:50518067-50518147 4.2e-05 50_[+1]_22 chr18:77748583-77748663 4.2e-05 [+1]_72 chrX:148622419-148622499 4.2e-05 57_[+1]_15 chr10:13203477-13203557 8.3e-05 43_[+1]_29 chrX:55026680-55026760 8.3e-05 34_[+1]_38 chr14:45722437-45722517 8.3e-05 46_[+1]_26 chr2:26256937-26257017 8.3e-05 10_[+1]_62 chr19:46088108-46088188 8.3e-05 3_[+1]_69 chr2:74648817-74648897 8.3e-05 46_[+1]_26 chr3:80819747-80819827 8.3e-05 35_[+1]_37 chr19:38085654-38085734 8.3e-05 8_[+1]_64 chr2:68479851-68479931 0.0001 7_[+1]_65 chr6:33539149-33539229 0.0001 33_[+1]_39 chr10:93683498-93683578 0.00012 31_[+1]_41 chr7:74508839-74508919 0.00012 3_[+1]_69 chrX:133507260-133507340 0.00012 58_[+1]_14 chr9:99616857-99616937 0.00014 30_[+1]_42 chr17:42144053-42144133 0.00014 [+1]_72 chr4:130014718-130014798 0.00014 41_[+1]_31 chr18:47013615-47013695 0.00014 63_[+1]_9 chr15:29561992-29562072 0.00014 59_[+1]_13 chr2:73053165-73053245 0.00014 22_[+1]_50 chr19:18451195-18451275 0.00016 20_[+1]_52 chr3:52719983-52720063 0.00016 38_[+1]_34 chrX:48334470-48334550 0.00016 13_[+1]_59 chr10:2357320-2357400 0.00018 56_[+1]_16 chr5:43121561-43121641 0.00018 58_[+1]_14 chr20:1373776-1373856 0.00024 [+1]_72 chr3:49761424-49761504 0.00024 14_[+1]_58 chr3:80819488-80819568 0.00024 58_[+1]_14 chr9:80850891-80850971 0.00024 34_[+1]_38 chr13:25875670-25875750 0.00025 68_[+1]_4 chr11:102980078-10298015 0.00025 2_[+1]_70 chr11:57435219-57435299 0.00027 25_[+1]_47 chr19:45972472-45972552 0.00027 18_[+1]_54 chr6:121655728-121655808 0.00029 3_[+1]_69 chr3:122102957-122103037 0.00036 57_[+1]_15 chr16:67217796-67217876 0.00036 65_[+1]_7 chr22:30162950-30163030 0.00036 23_[+1]_49 chr2:99953729-99953809 0.00036 69_[+1]_3 chr1:155243286-155243366 0.00036 19_[+1]_53 chr7:17980089-17980169 0.00041 49_[+1]_23 chr22:42017228-42017308 0.00041 18_[+1]_54 chr19:55987880-55987960 0.00041 70_[+1]_2 chr11:105948360-10594844 0.00041 25_[+1]_47 chr2:32288546-32288626 0.0005 67_[+1]_5 chr17:76250661-76250741 0.0005 30_[+1]_42 chr19:52207495-52207575 0.0005 10_[+1]_62 chr11:43333463-43333543 0.0005 34_[+1]_38 chrX:152110117-152110197 0.0005 8_[+1]_64 chrX:41193277-41193357 0.00053 72_[+1] chr1:2343995-2344075 0.00053 31_[+1]_41 chr6:168813819-168813899 0.00053 25_[+1]_47 chr13:32889533-32889613 0.0006 32_[+1]_40 chr1:22379139-22379219 0.0006 25_[+1]_47 chr15:31618619-31618699 0.00062 58_[+1]_14 chr6:117996507-117996587 0.00075 32_[+1]_40 chr19:1241639-1241719 0.00075 51_[+1]_21 chrX:119763997-119764077 0.00075 45_[+1]_27 chr14:52456109-52456189 0.00075 25_[+1]_47 chr8:59323840-59323920 0.00086 10_[+1]_62 chr5:52095909-52095989 0.001 36_[+1]_36 chr14:64108734-64108814 0.001 28_[+1]_44 chr16:27214789-27214869 0.001 21_[+1]_51 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CGTGCGTS MEME-1 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF CGTGCGTS width=8 seqs=89 chr7:102004265-102004345 ( 33) CGTGCGTG 1 chr12:57081999-57082079 ( 40) CGTGCGTG 1 chr19:12893310-12893390 ( 48) CGTGCGTG 1 chr12:64616039-64616119 ( 61) CGTGCGTG 1 chr19:57901157-57901237 ( 41) CGTGCGTG 1 chr17:78120961-78121041 ( 11) CGTGCGTG 1 chr13:48612057-48612137 ( 59) CGTGCGTG 1 chr9:139010691-139010771 ( 36) CGTGCGTG 1 chr7:72349868-72349948 ( 28) CGTGCGTG 1 chr4:175041681-175041761 ( 71) CGTGCGTG 1 chrX:106916332-106916412 ( 40) CGTGCGTG 1 chrX:47341959-47342039 ( 38) CGTGCGTG 1 chr7:76178611-76178691 ( 7) CGTGCGTG 1 chr4:24586165-24586245 ( 45) CGTGCGTG 1 chr1:40840244-40840324 ( 16) CGTGCGTG 1 chr20:61493507-61493587 ( 1) CGTGCGTG 1 chr14:96968633-96968713 ( 61) CGTGCGTG 1 chr20:56964204-56964284 ( 70) CGTGCGTG 1 chr2:109403153-109403233 ( 13) CGTGCGTG 1 chr17:80606306-80606386 ( 67) CGTGCGTG 1 chr2:227700740-227700820 ( 5) CGTGCGTG 1 chr6:169852554-169852634 ( 52) CGTGCGTG 1 chr22:25844006-25844086 ( 47) CGTGCGTG 1 chr19:57874707-57874787 ( 35) CGTGCGTG 1 chr13:28024308-28024388 ( 32) CGTGCGTG 1 chr7:50518067-50518147 ( 51) CGTGCGTG 1 chr18:77748583-77748663 ( 1) CGTGCGTG 1 chrX:148622419-148622499 ( 58) CGTGCGTG 1 chr10:13203477-13203557 ( 44) CGTGCGTC 1 chrX:55026680-55026760 ( 35) CGTGCGTC 1 chr14:45722437-45722517 ( 47) CGTGCGTC 1 chr2:26256937-26257017 ( 11) CGTGCGTC 1 chr19:46088108-46088188 ( 4) CGTGCGTC 1 chr2:74648817-74648897 ( 47) CGTGCGTC 1 chr3:80819747-80819827 ( 36) CGTGCGTC 1 chr19:38085654-38085734 ( 9) CGTGCGTC 1 chr2:68479851-68479931 ( 8) CTTGCGTG 1 chr6:33539149-33539229 ( 34) CTTGCGTG 1 chr10:93683498-93683578 ( 32) TGTGCGTG 1 chr7:74508839-74508919 ( 4) TGTGCGTG 1 chrX:133507260-133507340 ( 59) TGTGCGTG 1 chr9:99616857-99616937 ( 31) CTTGCGTC 1 chr17:42144053-42144133 ( 1) CTTGCGTC 1 chr4:130014718-130014798 ( 42) CTTGCGTC 1 chr18:47013615-47013695 ( 64) CTTGCGTC 1 chr15:29561992-29562072 ( 60) CTTGCGTC 1 chr2:73053165-73053245 ( 23) CTTGCGTC 1 chr19:18451195-18451275 ( 21) AGTGCGTG 1 chr3:52719983-52720063 ( 39) AGTGCGTG 1 chrX:48334470-48334550 ( 14) AGTGCGTG 1 chr10:2357320-2357400 ( 57) TGTGCGTC 1 chr5:43121561-43121641 ( 59) TGTGCGTC 1 chr20:1373776-1373856 ( 1) CCTGCGTG 1 chr3:49761424-49761504 ( 15) CGTACGTG 1 chr3:80819488-80819568 ( 59) CGTACGTG 1 chr9:80850891-80850971 ( 35) CCTGCGTG 1 chr13:25875670-25875750 ( 69) TTTGCGTG 1 chr11:102980078-10298015 ( 3) TTTGCGTG 1 chr11:57435219-57435299 ( 26) CGTGCGTA 1 chr19:45972472-45972552 ( 19) CGTGCGTA 1 chr6:121655728-121655808 ( 4) AGTGCGTC 1 chr3:122102957-122103037 ( 58) CCTGCGTC 1 chr16:67217796-67217876 ( 66) CGTACGTC 1 chr22:30162950-30163030 ( 24) CCTGCGTC 1 chr2:99953729-99953809 ( 70) CCTGCGTC 1 chr1:155243286-155243366 ( 20) CCTGCGTC 1 chr7:17980089-17980169 ( 50) CGTGCGTT 1 chr22:42017228-42017308 ( 19) CATGCGTG 1 chr19:55987880-55987960 ( 71) CGTGCGTT 1 chr11:105948360-10594844 ( 26) TTTGCGTC 1 chr2:32288546-32288626 ( 68) CGTGCGCG 1 chr17:76250661-76250741 ( 31) CGTGCGCG 1 chr19:52207495-52207575 ( 11) CGTGCGCG 1 chr11:43333463-43333543 ( 35) CGTGCGCG 1 chrX:152110117-152110197 ( 9) CGTGCGCG 1 chrX:41193277-41193357 ( 73) TGTACGTG 1 chr1:2343995-2344075 ( 32) TCTGCGTG 1 chr6:168813819-168813899 ( 26) TGTACGTG 1 chr13:32889533-32889613 ( 33) GGTGCGTG 1 chr1:22379139-22379219 ( 26) GGTGCGTG 1 chr15:31618619-31618699 ( 59) CATGCGTC 1 chr6:117996507-117996587 ( 33) CGTGCGCC 1 chr19:1241639-1241719 ( 52) CGTGCGCC 1 chrX:119763997-119764077 ( 46) ACTGCGTG 1 chr14:52456109-52456189 ( 26) CGTGCGCC 1 chr8:59323840-59323920 ( 11) CTTGCGCG 1 chr5:52095909-52095989 ( 37) GTTGCGTG 1 chr14:64108734-64108814 ( 29) CGTACGTA 1 chr16:27214789-27214869 ( 22) ACTGCGTC 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CGTGCGTS MEME-1 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 8.71255 E= 2.0e-028 -123 122 -334 -42 -281 -172 109 -18 -1312 -1312 -1312 260 -123 -1312 144 -1312 -1312 158 -1312 -1312 -1312 -1312 154 -1312 -1312 -172 -1312 244 -223 -8 88 -288 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CGTGCGTS MEME-1 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 89 E= 2.0e-028 0.067416 0.775281 0.033708 0.123596 0.022472 0.101124 0.730337 0.146067 0.000000 0.000000 0.000000 1.000000 0.067416 0.000000 0.932584 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.101124 0.000000 0.898876 0.033708 0.314607 0.629213 0.022472 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CGTGCGTS MEME-1 regular expression -------------------------------------------------------------------------------- CGTGCGT[GC] -------------------------------------------------------------------------------- Time 5.08 secs. ******************************************************************************** ******************************************************************************** MOTIF TGACGTCA MEME-2 width = 8 sites = 56 llr = 456 E-value = 5.4e-019 ******************************************************************************** -------------------------------------------------------------------------------- Motif TGACGTCA MEME-2 Description -------------------------------------------------------------------------------- Simplified A :19:::18 pos.-specific C 1::a:29: probability G :81:a1:2 matrix T 911::8:: bits 2.7 2.4 2.1 * 1.9 * * Relative 1.6 * ** * Entropy 1.3 * **** * (11.8 bits) 1.1 * ****** 0.8 ******** 0.5 ******** 0.3 ******** 0.0 -------- Multilevel TGACGTCA consensus sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGACGTCA MEME-2 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr10:13203477-13203557 52 8.92e-06 CGCGTGCGTC TGACGTCA AGGCAGGGGC chr10:27444194-27444274 51 8.92e-06 ggcggcgggg TGACGTCA CGGCCGCGCG chr15:76629069-76629149 8 8.92e-06 TGCGTGT TGACGTCA TGCTGCGTGC chr4:170541627-170541707 46 8.92e-06 GTCAACGTAG TGACGTCA CGCGTCGACG chr1:22379139-22379219 18 8.92e-06 TCCTGCGCGC TGACGTCA GGTGCGTGCC chr9:34178954-34179034 42 8.92e-06 CGCGGCGCCA TGACGTCA GACGCCCAAA chr5:112849337-112849417 36 8.92e-06 CCGGCCCTGG TGACGTCA TTACGCCCGC chr19:46088108-46088188 57 8.92e-06 AGGCGCATCC TGACGTCA CCCCGTCGAC chr3:46064576-46064656 21 8.92e-06 CCAGCGCGTG TGACGTCA Tggcgccgtg chr14:50329577-50329657 33 1.74e-05 TGCAGGGCAG TTACGTCA TTGGGGAGCG chr10:93683498-93683578 1 1.74e-05 . TTACGTCA CTTCCGGCGC chr17:58603558-58603638 53 1.74e-05 TGCGGCGTCA TGACGTAA GCGCACGCCG chr3:93698941-93699021 35 2.15e-05 CGCCTCGAAG TAACGTCA GCACGTCGAC chr17:4890901-4890981 69 2.15e-05 CAGCGGCGTC TAACGTCA CTGC chr19:36705593-36705673 1 2.15e-05 . TAACGTCA GGCCGCTGTG chr20:37377012-37377092 35 4.09e-05 TCGCGCGGCG TGACGTCG GGGGCGCGGT chr3:156544018-156544098 54 4.09e-05 ACGTGGGCCG TGACGTCG CCGCGCCCTG chr17:15902960-15903040 58 4.09e-05 CGAGACGGAG TGACGTCG GGGCGCGTCA chr2:200775951-200776031 68 4.09e-05 CGTCGGCCTC TGACGTCG TCGCC chr5:133304303-133304383 62 4.09e-05 CCCAGCGTGG TGACGTCG AAGCCTGGAG chr2:68479851-68479931 56 4.09e-05 CGGACGTCGG TGACGTCG CGTGGCGGAG chr16:47007567-47007647 70 4.09e-05 CGGTGCGCCG TGACGTCG CTG chrX:149106763-149106843 57 4.09e-05 agccacgcag tgacgtcg ccacgcacgt chr22:41809988-41810068 18 6.10e-05 GCGCAGCCCG TTACGTAA CCCCCCTCCC chr17:62833239-62833319 49 6.10e-05 CCCCGGCCCC TGACGCCA TCACGTTGGC chr17:43568069-43568149 63 6.10e-05 CCCCGGCCCC TGACGCCA TCACGTTGGC chr2:48667785-48667865 71 6.10e-05 GGTGGGGCAC TGACGCCA GA chr19:36390677-36390757 31 6.10e-05 CGCGGCGCGC TGACGCCA CGGCGCTCAC chr8:2075753-2075833 21 6.10e-05 TACCTCGGCG TGACGCCA TGACGCAGCC chr6:70506953-70507033 50 6.51e-05 GCGGACGCAG TGACATCA CCACGCTGCC chr5:140943864-140943944 44 6.51e-05 TCTAACGTGA TGACATCA CTACCAAACG chr12:57824834-57824914 5 7.64e-05 GCGT TGTCGTCA CCTCGTCCTG chr5:86708718-86708798 29 7.64e-05 GCTGGCGCGC TGTCGTCA CGATTACGCG chr19:58361126-58361206 71 7.64e-05 CGTGTGCACG TAACGTAA GG chr16:31119647-31119727 56 9.44e-05 GCCGCCCACG CGACGTCA CGGCGGCGGA chr4:169931452-169931532 1 9.44e-05 . CGACGTCA TCACGCACGG chr12:94853750-94853830 22 9.44e-05 CCCCCCACGC CGACGTCA CCCACGCCAC chr20:5100582-5100662 67 9.44e-05 CGCCGCGTTG CGACGTCA CCACGC chr10:120840414-12084049 2 1.37e-04 C TGGCGTCA CGCACGCCGA chr11:28129728-28129808 33 1.37e-04 GCCGCTCGCG TGATGTCA TCACGTCGGA chr22:42017228-42017308 28 1.37e-04 ACATGCGTGA TGACGTAG AGGGCGTTGA chr14:96968633-96968713 70 1.37e-04 GCGTGCGTGG TGGCGTCA GCA chr17:47755419-47755499 42 1.37e-04 CGGGGCGTCA TGGCGTCA GCACGTCGAC chr15:72766564-72766644 42 1.72e-04 CGGGGCGCAG TGACGCAA AGAGGAGTGA chr4:130014718-130014798 69 1.72e-04 GCGTTGGAGC TTACGCCA TCGC chr5:93447362-93447442 33 1.72e-04 ATTACGCACT TGACGGCA GCGGCGGCGA chr1:2343995-2344075 15 1.72e-04 CGAGAACTGA TGACGGCA CGACGTGGCT chr13:27825405-27825485 11 1.72e-04 GCGAAGGCGG TGACGCAA AGGATGGCGT chr18:77748583-77748663 10 1.72e-04 CGTGCGTGC TGACGGCA TGCGCGCGCG chr1:86861728-86861808 17 1.85e-04 CACGTCGTCG TGACGACA GCCCGCCGTC chr9:80850891-80850971 63 2.03e-04 GCGAGCACGT TGACGTCT TGGCGCACCG chr5:52095909-52095989 22 2.20e-04 TGCGCCTTCA TTTCGTCA GCCCGCTGTT chr16:30389138-30389218 44 2.39e-04 AAAACATCTG CTACGTCA TCACGCACGG chr4:187125364-187125444 52 3.10e-04 GACGCTACGC TGGCGTAA GACgcggcgg chr11:43333463-43333543 46 3.10e-04 GTGCGCGTCT TTACGTAG ACGTCGGGGG chr15:82555045-82555125 59 3.10e-04 CGCACGTCTC TGACGCCG CCGGAAGCCG -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGACGTCA MEME-2 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr10:13203477-13203557 8.9e-06 51_[+2]_21 chr10:27444194-27444274 8.9e-06 50_[+2]_22 chr15:76629069-76629149 8.9e-06 7_[+2]_65 chr4:170541627-170541707 8.9e-06 45_[+2]_27 chr1:22379139-22379219 8.9e-06 17_[+2]_55 chr9:34178954-34179034 8.9e-06 41_[+2]_31 chr5:112849337-112849417 8.9e-06 35_[+2]_37 chr19:46088108-46088188 8.9e-06 56_[+2]_16 chr3:46064576-46064656 8.9e-06 20_[+2]_52 chr14:50329577-50329657 1.7e-05 32_[+2]_40 chr10:93683498-93683578 1.7e-05 [+2]_72 chr17:58603558-58603638 1.7e-05 52_[+2]_20 chr3:93698941-93699021 2.2e-05 34_[+2]_38 chr17:4890901-4890981 2.2e-05 68_[+2]_4 chr19:36705593-36705673 2.2e-05 [+2]_72 chr20:37377012-37377092 4.1e-05 34_[+2]_38 chr3:156544018-156544098 4.1e-05 53_[+2]_19 chr17:15902960-15903040 4.1e-05 57_[+2]_15 chr2:200775951-200776031 4.1e-05 67_[+2]_5 chr5:133304303-133304383 4.1e-05 61_[+2]_11 chr2:68479851-68479931 4.1e-05 55_[+2]_17 chr16:47007567-47007647 4.1e-05 69_[+2]_3 chrX:149106763-149106843 4.1e-05 56_[+2]_16 chr22:41809988-41810068 6.1e-05 17_[+2]_55 chr17:62833239-62833319 6.1e-05 48_[+2]_24 chr17:43568069-43568149 6.1e-05 62_[+2]_10 chr2:48667785-48667865 6.1e-05 70_[+2]_2 chr19:36390677-36390757 6.1e-05 30_[+2]_42 chr8:2075753-2075833 6.1e-05 20_[+2]_52 chr6:70506953-70507033 6.5e-05 49_[+2]_23 chr5:140943864-140943944 6.5e-05 43_[+2]_29 chr12:57824834-57824914 7.6e-05 4_[+2]_68 chr5:86708718-86708798 7.6e-05 28_[+2]_44 chr19:58361126-58361206 7.6e-05 70_[+2]_2 chr16:31119647-31119727 9.4e-05 55_[+2]_17 chr4:169931452-169931532 9.4e-05 [+2]_72 chr12:94853750-94853830 9.4e-05 21_[+2]_51 chr20:5100582-5100662 9.4e-05 66_[+2]_6 chr10:120840414-12084049 0.00014 1_[+2]_71 chr11:28129728-28129808 0.00014 32_[+2]_40 chr22:42017228-42017308 0.00014 27_[+2]_45 chr14:96968633-96968713 0.00014 69_[+2]_3 chr17:47755419-47755499 0.00014 41_[+2]_31 chr15:72766564-72766644 0.00017 41_[+2]_31 chr4:130014718-130014798 0.00017 68_[+2]_4 chr5:93447362-93447442 0.00017 32_[+2]_40 chr1:2343995-2344075 0.00017 14_[+2]_58 chr13:27825405-27825485 0.00017 10_[+2]_62 chr18:77748583-77748663 0.00017 9_[+2]_63 chr1:86861728-86861808 0.00018 16_[+2]_56 chr9:80850891-80850971 0.0002 62_[+2]_10 chr5:52095909-52095989 0.00022 21_[+2]_51 chr16:30389138-30389218 0.00024 43_[+2]_29 chr4:187125364-187125444 0.00031 51_[+2]_21 chr11:43333463-43333543 0.00031 45_[+2]_27 chr15:82555045-82555125 0.00031 58_[+2]_14 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGACGTCA MEME-2 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF TGACGTCA width=8 seqs=56 chr10:13203477-13203557 ( 52) TGACGTCA 1 chr10:27444194-27444274 ( 51) TGACGTCA 1 chr15:76629069-76629149 ( 8) TGACGTCA 1 chr4:170541627-170541707 ( 46) TGACGTCA 1 chr1:22379139-22379219 ( 18) TGACGTCA 1 chr9:34178954-34179034 ( 42) TGACGTCA 1 chr5:112849337-112849417 ( 36) TGACGTCA 1 chr19:46088108-46088188 ( 57) TGACGTCA 1 chr3:46064576-46064656 ( 21) TGACGTCA 1 chr14:50329577-50329657 ( 33) TTACGTCA 1 chr10:93683498-93683578 ( 1) TTACGTCA 1 chr17:58603558-58603638 ( 53) TGACGTAA 1 chr3:93698941-93699021 ( 35) TAACGTCA 1 chr17:4890901-4890981 ( 69) TAACGTCA 1 chr19:36705593-36705673 ( 1) TAACGTCA 1 chr20:37377012-37377092 ( 35) TGACGTCG 1 chr3:156544018-156544098 ( 54) TGACGTCG 1 chr17:15902960-15903040 ( 58) TGACGTCG 1 chr2:200775951-200776031 ( 68) TGACGTCG 1 chr5:133304303-133304383 ( 62) TGACGTCG 1 chr2:68479851-68479931 ( 56) TGACGTCG 1 chr16:47007567-47007647 ( 70) TGACGTCG 1 chrX:149106763-149106843 ( 57) TGACGTCG 1 chr22:41809988-41810068 ( 18) TTACGTAA 1 chr17:62833239-62833319 ( 49) TGACGCCA 1 chr17:43568069-43568149 ( 63) TGACGCCA 1 chr2:48667785-48667865 ( 71) TGACGCCA 1 chr19:36390677-36390757 ( 31) TGACGCCA 1 chr8:2075753-2075833 ( 21) TGACGCCA 1 chr6:70506953-70507033 ( 50) TGACATCA 1 chr5:140943864-140943944 ( 44) TGACATCA 1 chr12:57824834-57824914 ( 5) TGTCGTCA 1 chr5:86708718-86708798 ( 29) TGTCGTCA 1 chr19:58361126-58361206 ( 71) TAACGTAA 1 chr16:31119647-31119727 ( 56) CGACGTCA 1 chr4:169931452-169931532 ( 1) CGACGTCA 1 chr12:94853750-94853830 ( 22) CGACGTCA 1 chr20:5100582-5100662 ( 67) CGACGTCA 1 chr10:120840414-12084049 ( 2) TGGCGTCA 1 chr11:28129728-28129808 ( 33) TGATGTCA 1 chr22:42017228-42017308 ( 28) TGACGTAG 1 chr14:96968633-96968713 ( 70) TGGCGTCA 1 chr17:47755419-47755499 ( 42) TGGCGTCA 1 chr15:72766564-72766644 ( 42) TGACGCAA 1 chr4:130014718-130014798 ( 69) TTACGCCA 1 chr5:93447362-93447442 ( 33) TGACGGCA 1 chr1:2343995-2344075 ( 15) TGACGGCA 1 chr13:27825405-27825485 ( 11) TGACGCAA 1 chr18:77748583-77748663 ( 10) TGACGGCA 1 chr1:86861728-86861808 ( 17) TGACGACA 1 chr9:80850891-80850971 ( 63) TGACGTCT 1 chr5:52095909-52095989 ( 22) TTTCGTCA 1 chr16:30389138-30389218 ( 44) CTACGTCA 1 chr4:187125364-187125444 ( 52) TGGCGTAA 1 chr11:43333463-43333543 ( 46) TTACGTAG 1 chr15:82555045-82555125 ( 59) TGACGCCG 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGACGTCA MEME-2 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 10.0167 E= 5.4e-019 -1245 -190 -1245 246 -115 -1245 123 -40 247 -1245 -226 -163 -1245 156 -1245 -321 -215 -1245 149 -1245 -314 -105 -268 222 -15 136 -1245 -1245 231 -1245 -80 -321 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGACGTCA MEME-2 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 56 E= 5.4e-019 0.000000 0.089286 0.000000 0.910714 0.071429 0.000000 0.803571 0.125000 0.875000 0.000000 0.071429 0.053571 0.000000 0.982143 0.000000 0.017857 0.035714 0.000000 0.964286 0.000000 0.017857 0.160714 0.053571 0.767857 0.142857 0.857143 0.000000 0.000000 0.785714 0.000000 0.196429 0.017857 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGACGTCA MEME-2 regular expression -------------------------------------------------------------------------------- TGACGTCA -------------------------------------------------------------------------------- Time 8.73 secs. ******************************************************************************** ******************************************************************************** MOTIF ABARAAAM MEME-3 width = 8 sites = 11 llr = 112 E-value = 4.4e+001 ******************************************************************************** -------------------------------------------------------------------------------- Motif ABARAAAM MEME-3 Description -------------------------------------------------------------------------------- Simplified A 7:a69aa5 pos.-specific C :4:::::5 probability G :4:4:::: matrix T 33::1::: bits 2.7 * ** 2.4 * ** 2.1 * *** 1.9 * * *** Relative 1.6 * * *** Entropy 1.3 * ***** (14.8 bits) 1.1 * ****** 0.8 * ****** 0.5 * ****** 0.3 ******** 0.0 -------- Multilevel ACAAAAAA consensus TG G C sequence T -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ABARAAAM MEME-3 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr16:30569679-30569759 30 4.06e-07 ATATGCCCTC ATAAAAAA TGGCGGCGGC chr1:86861728-86861808 43 4.06e-07 TCGCCGCGAT ATAAAAAA AGGGTCAGAG chr2:32288546-32288626 51 7.75e-06 CGCGCGCCGG AGAAAAAC ACGGGAAGAC chr16:30389138-30389218 31 7.75e-06 AACGTCGACT ACAAAAAC ATCTGCTACG chr16:2802506-2802586 16 9.49e-06 TCCTTGTGCC TGAAAAAA CGGTACTTCG chr8:101734401-101734481 50 1.31e-05 ggaggaggga agagaaaa caggaggaaa chr3:46064576-46064656 2 1.40e-05 T TTAAAAAC ACCAGCGCGT chr4:100485118-100485198 35 2.85e-05 GCTTCCTTCC ACAGAAAC TTCAATTCCC chr19:58446766-58446846 26 2.85e-05 ACGTGCGCAC ACAGAAAC GCCTTTATTC chr9:101984299-101984379 38 3.23e-05 AGTAACTGCC TGAGAAAA TATCTTGTCT chr14:52456109-52456189 1 3.40e-05 . ACAATAAA GTTTATTTGA -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ABARAAAM MEME-3 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr16:30569679-30569759 4.1e-07 29_[+3]_43 chr1:86861728-86861808 4.1e-07 42_[+3]_30 chr2:32288546-32288626 7.7e-06 50_[+3]_22 chr16:30389138-30389218 7.7e-06 30_[+3]_42 chr16:2802506-2802586 9.5e-06 15_[+3]_57 chr8:101734401-101734481 1.3e-05 49_[+3]_23 chr3:46064576-46064656 1.4e-05 1_[+3]_71 chr4:100485118-100485198 2.9e-05 34_[+3]_38 chr19:58446766-58446846 2.9e-05 25_[+3]_47 chr9:101984299-101984379 3.2e-05 37_[+3]_35 chr14:52456109-52456189 3.4e-05 [+3]_72 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ABARAAAM MEME-3 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF ABARAAAM width=8 seqs=11 chr16:30569679-30569759 ( 30) ATAAAAAA 1 chr1:86861728-86861808 ( 43) ATAAAAAA 1 chr2:32288546-32288626 ( 51) AGAAAAAC 1 chr16:30389138-30389218 ( 31) ACAAAAAC 1 chr16:2802506-2802586 ( 16) TGAAAAAA 1 chr8:101734401-101734481 ( 50) AGAGAAAA 1 chr3:46064576-46064656 ( 2) TTAAAAAC 1 chr4:100485118-100485198 ( 35) ACAGAAAC 1 chr19:58446766-58446846 ( 26) ACAGAAAC 1 chr9:101984299-101984379 ( 38) TGAGAAAA 1 chr14:52456109-52456189 ( 1) ACAATAAA 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ABARAAAM MEME-3 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 12.2293 E= 4.4e+001 220 -1010 -1010 72 -1010 12 8 72 266 -1010 -1010 -1010 201 -1010 8 -1010 252 -1010 -1010 -86 266 -1010 -1010 -1010 266 -1010 -1010 -1010 179 45 -1010 -1010 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ABARAAAM MEME-3 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 11 E= 4.4e+001 0.727273 0.000000 0.000000 0.272727 0.000000 0.363636 0.363636 0.272727 1.000000 0.000000 0.000000 0.000000 0.636364 0.000000 0.363636 0.000000 0.909091 0.000000 0.000000 0.090909 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.545455 0.454545 0.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ABARAAAM MEME-3 regular expression -------------------------------------------------------------------------------- [AT][CGT]A[AG]AAA[AC] -------------------------------------------------------------------------------- Time 12.29 secs. ******************************************************************************** ******************************************************************************** MOTIF TACAWTTC MEME-4 width = 8 sites = 7 llr = 78 E-value = 8.2e+002 ******************************************************************************** -------------------------------------------------------------------------------- Motif TACAWTTC MEME-4 Description -------------------------------------------------------------------------------- Simplified A :9:a6::: pos.-specific C ::a::3:a probability G :::::::: matrix T a1::47a: bits 2.7 * * * 2.4 * * * 2.1 ** * * 1.9 ** * * Relative 1.6 ***** ** Entropy 1.3 ******** (16.2 bits) 1.1 ******** 0.8 ******** 0.5 ******** 0.3 ******** 0.0 -------- Multilevel TACAATTC consensus TC sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TACAWTTC MEME-4 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr19:12917280-12917360 11 1.98e-06 CCTTCGGGAC TACAATTC CCAGGAGGGC chr9:99616857-99616937 14 4.04e-06 CATTCAGGAC TACATTTC CCATAAGCTC chr2:44001109-44001189 4 4.04e-06 AAC TACATTTC CCATGATGCC chr19:38183209-38183289 25 4.04e-06 TAGCCCGGAA TACATTTC CCAGAGGCCT chr19:19887277-19887357 42 8.04e-06 GTAAAGAGAC TACAACTC CCAGCATACC chr16:31119647-31119727 19 8.04e-06 CAGACCAAAC TACAACTC CCAGGACCCA chr4:100485118-100485198 43 1.01e-05 CCACAGAAAC TTCAATTC CCAGAGGCAG -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TACAWTTC MEME-4 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr19:12917280-12917360 2e-06 10_[+4]_62 chr9:99616857-99616937 4e-06 13_[+4]_59 chr2:44001109-44001189 4e-06 3_[+4]_69 chr19:38183209-38183289 4e-06 24_[+4]_48 chr19:19887277-19887357 8e-06 41_[+4]_31 chr16:31119647-31119727 8e-06 18_[+4]_54 chr4:100485118-100485198 1e-05 42_[+4]_30 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TACAWTTC MEME-4 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF TACAWTTC width=8 seqs=7 chr19:12917280-12917360 ( 11) TACAATTC 1 chr9:99616857-99616937 ( 14) TACATTTC 1 chr2:44001109-44001189 ( 4) TACATTTC 1 chr19:38183209-38183289 ( 25) TACATTTC 1 chr19:19887277-19887357 ( 42) TACAACTC 1 chr16:31119647-31119727 ( 19) TACAACTC 1 chr4:100485118-100485198 ( 43) TTCAATTC 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TACAWTTC MEME-4 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 11.1915 E= 8.2e+002 -945 -945 -945 259 244 -945 -945 -21 -945 158 -945 -945 266 -945 -945 -945 185 -945 -945 137 -945 -22 -945 211 -945 -945 -945 259 -945 158 -945 -945 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TACAWTTC MEME-4 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 7 E= 8.2e+002 0.000000 0.000000 0.000000 1.000000 0.857143 0.000000 0.000000 0.142857 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.571429 0.000000 0.000000 0.428571 0.000000 0.285714 0.000000 0.714286 0.000000 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TACAWTTC MEME-4 regular expression -------------------------------------------------------------------------------- TACA[AT][TC]TC -------------------------------------------------------------------------------- Time 15.86 secs. ******************************************************************************** ******************************************************************************** MOTIF TRCGTGCG MEME-5 width = 8 sites = 27 llr = 231 E-value = 2.4e+002 ******************************************************************************** -------------------------------------------------------------------------------- Motif TRCGTGCG MEME-5 Description -------------------------------------------------------------------------------- Simplified A :5:::::1 pos.-specific C 1:a:::9: probability G :5:a:a:9 matrix T 9:::a:1: bits 2.7 * 2.4 * 2.1 * 1.9 * * Relative 1.6 * ** Entropy 1.3 * **** * (12.3 bits) 1.1 ******** 0.8 ******** 0.5 ******** 0.3 ******** 0.0 -------- Multilevel TACGTGCG consensus G sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TRCGTGCG MEME-5 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr11:57435219-57435299 2 1.94e-05 T TACGTGCG CGCTCTCGTC chr19:58446766-58446846 15 1.94e-05 GCCACTACGT TACGTGCG CACACAGAAA chr17:78120961-78121041 29 1.94e-05 cgtacgtgcg tacgtgcg tacgcgcgAC chr13:25875670-25875750 39 1.94e-05 TCCGGCGGGC TACGTGCG CGCGGCGAGC chr3:80819488-80819568 41 1.94e-05 CCTCTCAACG TACGTGCG CTCCTCTCAA chr17:80606306-80606386 23 1.94e-05 GTGCCGGAcg tacgtgcg tgcgtgctgg chr3:80819747-80819827 2 1.94e-05 G TACGTGCG CTCCTCTCAA chr7:50518067-50518147 21 1.94e-05 ACTCGCGCcg tacgtgcg tgcgtgagtg chr7:102004265-102004345 17 6.14e-05 CACCTCTCCC TGCGTGCG TGTTCGCGCG chr15:76629069-76629149 19 6.14e-05 GACGTCATGC TGCGTGCG GGCCGGTGCG chr9:139010691-139010771 26 6.14e-05 CCCGAGGgcg tgcgtgcg tgcgtgcgtg chr7:72349868-72349948 12 6.14e-05 CACCTCTCCC TGCGTGCG TGTTCGCGCG chr4:175041681-175041761 51 6.14e-05 tgtgtgcgcg tgcgtgcg tgtgtgtgcg chrX:106916332-106916412 30 6.14e-05 cgtgtgtgcg tgcgtgcg tgcgtgcgtg chr1:40840244-40840324 6 6.14e-05 TGCAT tgcgtgcg tgcgtgcgtg chr20:56964204-56964284 60 6.14e-05 tgtacgactc tgcgtgcg tgcgtgcgtg chr19:57874707-57874787 25 6.14e-05 AAGGAACCTT tgcgtgcg tgcgtgcgtg chr19:58427978-58428058 11 7.99e-05 AGCCTTACGT TACGTGCA CACGTGGAAA chr6:168813819-168813899 60 8.90e-05 CGGGAGCGTG TACGTGAG CGTGGCGGGC chr19:46088108-46088188 22 1.08e-04 AGTACGTATG TACGTACG CTCGAGGGAA chr4:24586165-24586245 63 1.48e-04 cgtgcgagtg tgcgtgtg agcgaggtgc chr17:58603558-58603638 37 1.48e-04 GGGGCGGGGC TGCGTGTG CGGCGTCATG chr7:74508839-74508919 50 1.48e-04 GCGCTCGCGC TGCGTGCA GACGCGCTTG chr11:120894733-12089481 35 1.87e-04 GCGGACGTGA CACGTGCG GCGGGGTCAC chr20:61493507-61493587 9 1.87e-04 CGTGCGTG CACGTGCG CCCCATTACA chr2:227700740-227700820 19 1.87e-04 CGTGATGACG CACGTGCG CGCGAAGACG chr7:38217751-38217831 72 2.47e-04 AGATGCGAGC TGTGTGCG T -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TRCGTGCG MEME-5 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr11:57435219-57435299 1.9e-05 1_[+5]_71 chr19:58446766-58446846 1.9e-05 14_[+5]_58 chr17:78120961-78121041 1.9e-05 28_[+5]_44 chr13:25875670-25875750 1.9e-05 38_[+5]_34 chr3:80819488-80819568 1.9e-05 40_[+5]_32 chr17:80606306-80606386 1.9e-05 22_[+5]_50 chr3:80819747-80819827 1.9e-05 1_[+5]_71 chr7:50518067-50518147 1.9e-05 20_[+5]_52 chr7:102004265-102004345 6.1e-05 16_[+5]_56 chr15:76629069-76629149 6.1e-05 18_[+5]_54 chr9:139010691-139010771 6.1e-05 25_[+5]_47 chr7:72349868-72349948 6.1e-05 11_[+5]_61 chr4:175041681-175041761 6.1e-05 50_[+5]_22 chrX:106916332-106916412 6.1e-05 29_[+5]_43 chr1:40840244-40840324 6.1e-05 5_[+5]_67 chr20:56964204-56964284 6.1e-05 59_[+5]_13 chr19:57874707-57874787 6.1e-05 24_[+5]_48 chr19:58427978-58428058 8e-05 10_[+5]_62 chr6:168813819-168813899 8.9e-05 59_[+5]_13 chr19:46088108-46088188 0.00011 21_[+5]_51 chr4:24586165-24586245 0.00015 62_[+5]_10 chr17:58603558-58603638 0.00015 36_[+5]_36 chr7:74508839-74508919 0.00015 49_[+5]_23 chr11:120894733-12089481 0.00019 34_[+5]_38 chr20:61493507-61493587 0.00019 8_[+5]_64 chr2:227700740-227700820 0.00019 18_[+5]_54 chr7:38217751-38217831 0.00025 71_[+5]_1 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TRCGTGCG MEME-5 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF TRCGTGCG width=8 seqs=27 chr11:57435219-57435299 ( 2) TACGTGCG 1 chr19:58446766-58446846 ( 15) TACGTGCG 1 chr17:78120961-78121041 ( 29) TACGTGCG 1 chr13:25875670-25875750 ( 39) TACGTGCG 1 chr3:80819488-80819568 ( 41) TACGTGCG 1 chr17:80606306-80606386 ( 23) TACGTGCG 1 chr3:80819747-80819827 ( 2) TACGTGCG 1 chr7:50518067-50518147 ( 21) TACGTGCG 1 chr7:102004265-102004345 ( 17) TGCGTGCG 1 chr15:76629069-76629149 ( 19) TGCGTGCG 1 chr9:139010691-139010771 ( 26) TGCGTGCG 1 chr7:72349868-72349948 ( 12) TGCGTGCG 1 chr4:175041681-175041761 ( 51) TGCGTGCG 1 chrX:106916332-106916412 ( 30) TGCGTGCG 1 chr1:40840244-40840324 ( 6) TGCGTGCG 1 chr20:56964204-56964284 ( 60) TGCGTGCG 1 chr19:57874707-57874787 ( 25) TGCGTGCG 1 chr19:58427978-58428058 ( 11) TACGTGCA 1 chr6:168813819-168813899 ( 60) TACGTGAG 1 chr19:46088108-46088188 ( 22) TACGTACG 1 chr4:24586165-24586245 ( 63) TGCGTGTG 1 chr17:58603558-58603638 ( 37) TGCGTGTG 1 chr7:74508839-74508919 ( 50) TGCGTGCA 1 chr11:120894733-12089481 ( 35) CACGTGCG 1 chr20:61493507-61493587 ( 9) CACGTGCG 1 chr2:227700740-227700820 ( 19) CACGTGCG 1 chr7:38217751-38217831 ( 72) TGTGTGCG 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TRCGTGCG MEME-5 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 10.594 E= 2.4e+002 -1140 -159 -1140 243 171 -1140 49 -1140 -1140 153 -1140 -216 -1140 -1140 154 -1140 -1140 -1140 -1140 260 -209 -1140 149 -1140 -209 141 -1140 -116 -109 -1140 143 -1140 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TRCGTGCG MEME-5 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 27 E= 2.4e+002 0.000000 0.111111 0.000000 0.888889 0.518519 0.000000 0.481481 0.000000 0.000000 0.962963 0.000000 0.037037 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.037037 0.000000 0.962963 0.000000 0.037037 0.888889 0.000000 0.074074 0.074074 0.000000 0.925926 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TRCGTGCG MEME-5 regular expression -------------------------------------------------------------------------------- T[AG]CGTGCG -------------------------------------------------------------------------------- Time 19.40 secs. ******************************************************************************** ******************************************************************************** SUMMARY OF MOTIFS ******************************************************************************** -------------------------------------------------------------------------------- Combined block diagrams: non-overlapping sites with p-value < 0.0001 -------------------------------------------------------------------------------- SEQUENCE NAME COMBINED P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chrX:148622419-148622499 2.37e-03 55_[+5(1.94e-05)]_17 chr18:77748583-77748663 2.15e-03 [+1(4.20e-05)]_26_[+1(4.20e-05)]_38 chrX:133507260-133507340 8.64e-03 60_[+5(6.14e-05)]_12 chr7:50518067-50518147 4.77e-03 20_[+5(1.94e-05)]_18_[+1(4.20e-05)]_\ 26 chr13:28024308-28024388 2.56e-04 27_[+1(4.20e-05)]_45 chr2:73053165-73053245 1.18e-02 80 chrX:149106763-149106843 4.48e-03 56_[+2(4.09e-05)]_16 chr9:80850891-80850971 1.80e-02 80 chr17:47755419-47755499 1.00e-01 80 chr19:38085654-38085734 1.42e-02 8_[+1(8.30e-05)]_64 chr8:2075753-2075833 1.02e-01 20_[+2(6.10e-05)]_52 chr3:80819747-80819827 2.84e-03 1_[+5(1.94e-05)]_26_[+1(8.30e-05)]_\ 37 chr19:57874707-57874787 4.54e-03 26_[+1(4.20e-05)]_[+1(4.20e-05)]_\ [+1(8.30e-05)]_30 chr22:25844006-25844086 1.70e-02 28_[+1(4.20e-05)]_1_[+1(4.20e-05)]_\ 1_[+1(4.20e-05)]_26 chr6:169852554-169852634 4.07e-02 51_[+1(4.20e-05)]_21 chr7:74508839-74508919 6.08e-04 80 chr12:44152604-44152684 8.66e-02 80 chr2:227700740-227700820 6.69e-03 4_[+1(4.20e-05)]_68 chr19:58361126-58361206 3.91e-03 70_[+2(7.64e-05)]_2 chr17:80606306-80606386 5.81e-03 22_[+5(1.94e-05)]_28_[+1(4.20e-05)]_\ [+1(4.20e-05)]_6 chr13:21872186-21872266 2.39e-01 80 chrX:30265136-30265216 1.44e-01 80 chr6:121655728-121655808 8.75e-03 80 chr15:29561992-29562072 1.91e-02 80 chr19:36705593-36705673 4.44e-02 [+2(2.15e-05)]_72 chr1:155243286-155243366 2.33e-01 80 chr16:30389138-30389218 6.95e-04 30_[+3(7.75e-06)]_42 chr10:119135074-11913515 4.71e-01 80 chr16:27214789-27214869 3.88e-01 80 chr19:36390677-36390757 3.88e-02 30_[+2(6.10e-05)]_42 chr14:52456109-52456189 1.95e-03 [+3(3.40e-05)]_72 chr4:148605347-148605427 6.66e-01 80 chr19:50169126-50169206 6.05e-01 80 chr3:46064576-46064656 4.54e-05 1_[+3(1.40e-05)]_11_[+2(8.92e-06)]_\ 52 chr2:74648817-74648897 1.77e-03 44_[+5(1.94e-05)]_28 chr2:48667785-48667865 1.01e-01 70_[+2(6.10e-05)]_2 chr7:66057324-66057404 4.03e-01 80 chr15:31618619-31618699 2.25e-01 80 chr2:109403153-109403233 4.43e-02 12_[+1(4.20e-05)]_60 chr20:56964204-56964284 7.12e-04 37_[+1(4.20e-05)]_16_[+1(4.20e-05)]_\ [+1(4.20e-05)]_3 chr19:45972472-45972552 3.89e-02 80 chr2:219433025-219433105 7.01e-01 80 chr11:105948360-10594844 1.45e-01 80 chr6:79788202-79788282 9.92e-01 80 chr2:99953729-99953809 5.82e-01 80 chr4:6711630-6711710 3.60e-01 80 chr18:47013615-47013695 6.32e-03 80 chr17:40610843-40610923 9.03e-01 80 chr14:96968633-96968713 3.79e-03 60_[+1(4.20e-05)]_12 chr6:33539149-33539229 5.78e-02 80 chr17:18684513-18684593 4.68e-01 80 chr5:43121561-43121641 3.14e-02 80 chr5:139487350-139487430 4.63e-01 80 chr11:102980078-10298015 5.84e-03 4_[+5(6.14e-05)]_68 chr17:58603558-58603638 1.25e-03 52_[+2(1.74e-05)]_20 chr5:140943864-140943944 3.05e-02 43_[+2(6.51e-05)]_29 chr14:64108734-64108814 8.67e-03 80 chr11:6255902-6255982 8.29e-01 80 chr20:61493507-61493587 1.90e-04 [+1(4.20e-05)]_72 chr13:20207714-20207794 9.01e-01 80 chr16:47007567-47007647 8.87e-02 69_[+2(4.09e-05)]_3 chr20:43150683-43150763 7.57e-01 80 chr12:50677435-50677515 9.29e-01 80 chr17:43568069-43568149 1.47e-01 62_[+2(6.10e-05)]_10 chr8:17104326-17104406 6.85e-01 80 chr11:134582244-13458232 8.04e-01 80 chr5:89825379-89825459 1.71e-01 80 chr15:82555045-82555125 2.37e-01 80 chr17:62833239-62833319 1.59e-01 48_[+2(6.10e-05)]_24 chr7:38217751-38217831 1.14e-01 80 chr14:75760897-75760977 7.28e-01 80 chr20:3451470-3451550 1.02e-01 80 chr19:33071845-33071925 7.14e-01 80 chr19:46088108-46088188 5.15e-06 1_[+5(6.14e-05)]_47_[+2(8.92e-06)]_\ 16 chr17:61904497-61904577 2.84e-01 80 chr4:140005388-140005468 6.38e-01 80 chr7:39989159-39989239 4.89e-01 80 chr1:40840244-40840324 2.07e-04 7_[+1(4.20e-05)]_[+1(4.20e-05)]_57 chrX:152110117-152110197 2.30e-02 80 chr5:87564687-87564767 7.75e-01 80 chr11:78285804-78285884 2.08e-01 80 chr11:43333463-43333543 2.18e-02 80 chr15:41099755-41099835 6.69e-02 80 chr1:113615791-113615871 6.75e-01 80 chr2:68479851-68479931 5.47e-04 55_[+2(4.09e-05)]_17 chr3:80819488-80819568 9.25e-03 40_[+5(1.94e-05)]_12_[+5(1.94e-05)]_\ 12 chr22:43539413-43539493 2.65e-01 80 chrX:48334470-48334550 1.25e-01 80 chr1:86861728-86861808 5.46e-04 42_[+3(4.06e-07)]_30 chr18:77439666-77439746 9.90e-01 80 chr3:49761424-49761504 5.19e-02 80 chr14:60558651-60558731 9.67e-01 80 chr4:24586165-24586245 8.37e-03 44_[+1(4.20e-05)]_28 chr6:70506953-70507033 1.25e-02 49_[+2(6.51e-05)]_23 chr7:1015111-1015191 3.14e-01 80 chr5:86708718-86708798 4.15e-03 28_[+2(7.64e-05)]_44 chr13:27825405-27825485 2.24e-01 80 chr19:55987880-55987960 1.19e-02 68_[+5(1.94e-05)]_4 chr19:38183209-38183289 1.95e-02 24_[+4(4.04e-06)]_48 chr7:76178611-76178691 9.55e-03 6_[+1(4.20e-05)]_66 chr6:168813819-168813899 8.25e-02 4_[+5(8.90e-05)]_15_[+5(8.90e-05)]_\ 24_[+5(8.90e-05)]_13 chr14:50779043-50779123 6.02e-01 80 chr16:475447-475527 2.38e-01 80 chr4:187125364-187125444 3.07e-01 80 chr5:112849337-112849417 1.10e-02 35_[+2(8.92e-06)]_37 chr2:44001109-44001189 5.71e-03 3_[+4(4.04e-06)]_69 chr19:40336962-40337042 1.00e-01 80 chr14:105195773-10519585 7.66e-02 80 chr16:20911827-20911907 8.11e-02 80 chr14:93260436-93260516 4.73e-01 80 chrX:47341959-47342039 8.63e-04 37_[+1(4.20e-05)]_35 chrX:106916332-106916412 3.17e-03 27_[+1(4.20e-05)]_[+1(4.20e-05)]_37 chr4:175041681-175041761 1.31e-02 48_[+1(4.20e-05)]_10_[+1(4.20e-05)]_\ 6 chr7:72349868-72349948 5.97e-03 13_[+1(4.20e-05)]_6_[+1(4.20e-05)]_\ 45 chrX:119763997-119764077 2.11e-01 80 chr20:55904825-55904905 6.57e-01 80 chr19:57999011-57999091 1.38e-01 80 chr9:34178954-34179034 1.61e-02 41_[+2(8.92e-06)]_31 chr4:187422081-187422161 9.07e-01 80 chr22:41809988-41810068 5.22e-02 17_[+2(6.10e-05)]_55 chr13:25875670-25875750 1.78e-04 22_[+4(4.13e-05)]_8_[+5(1.94e-05)]_\ 34 chr19:42463524-42463604 8.01e-01 80 chr20:5100582-5100662 2.61e-02 66_[+2(9.44e-05)]_6 chr5:133304303-133304383 2.26e-02 61_[+2(4.09e-05)]_11 chr20:1373776-1373856 1.85e-02 2_[+5(6.14e-05)]_70 chr8:2075406-2075486 4.49e-01 80 chr10:93683498-93683578 1.03e-04 [+2(1.74e-05)]_72 chr6:146285433-146285513 5.39e-01 80 chr1:22379139-22379219 2.05e-03 17_[+2(8.92e-06)]_55 chr20:42219457-42219537 2.08e-01 80 chr16:4526351-4526431 2.74e-01 80 chr12:94853750-94853830 2.36e-01 21_[+2(9.44e-05)]_51 chr7:98741896-98741976 8.59e-01 80 chr22:42017228-42017308 1.43e-02 80 chr5:52095909-52095989 5.26e-04 17_[+4(1.64e-05)]_55 chr13:24463561-24463641 6.97e-01 80 chr7:56119320-56119400 9.92e-01 80 chr9:139010691-139010771 6.10e-03 23_[+1(4.20e-05)]_[+1(4.20e-05)]_41 chr3:52719983-52720063 1.75e-03 80 chr22:30162950-30163030 2.51e-01 80 chr6:38607810-38607890 7.40e-01 80 chr1:2343995-2344075 2.25e-03 33_[+5(6.14e-05)]_39 chr8:59323840-59323920 1.60e-01 80 chr4:170541627-170541707 3.13e-03 45_[+2(8.92e-06)]_27 chr2:26256937-26257017 3.98e-03 8_[+5(6.14e-05)]_64 chr1:115053864-115053944 1.59e-01 80 chr17:73178987-73179067 3.36e-01 80 chr16:30569679-30569759 1.17e-03 29_[+3(4.06e-07)]_43 chr14:45722437-45722517 1.64e-02 46_[+1(8.30e-05)]_26 chrX:41193277-41193357 3.16e-01 80 chr13:48612057-48612137 9.25e-03 58_[+1(4.20e-05)]_14 chr11:120894733-12089481 1.06e-01 80 chr4:169931452-169931532 1.00e-02 [+2(9.44e-05)]_72 chr15:76629069-76629149 3.69e-06 7_[+2(8.92e-06)]_3_[+5(6.14e-05)]_\ 20_[+4(2.06e-05)]_26 chr19:18451195-18451275 8.34e-03 80 chr17:78120961-78121041 2.33e-03 10_[+1(4.20e-05)]_2_[+5(1.94e-05)]_\ [+5(1.94e-05)]_44 chr5:93447362-93447442 8.81e-02 80 chr19:58446766-58446846 1.47e-04 14_[+5(1.94e-05)]_3_[+3(2.85e-05)]_\ 47 chrX:15693619-15693699 5.33e-01 80 chr19:57901157-57901237 7.39e-04 40_[+1(4.20e-05)]_32 chr11:82904662-82904742 5.05e-01 80 chr4:130014718-130014798 9.05e-03 80 chr6:146136059-146136139 8.97e-01 80 chr4:2538121-2538201 9.76e-01 80 chr19:17008523-17008603 2.70e-01 80 chr17:4890901-4890981 1.04e-01 68_[+2(2.15e-05)]_4 chr12:57824834-57824914 2.40e-02 4_[+2(7.64e-05)]_68 chr19:58427978-58428058 1.12e-02 10_[+5(7.99e-05)]_62 chr11:28129728-28129808 3.56e-02 80 chr19:52207495-52207575 2.63e-01 80 chr3:93698941-93699021 9.22e-02 34_[+2(2.15e-05)]_38 chr16:67217796-67217876 2.25e-01 80 chr15:68346389-68346469 3.08e-01 80 chr17:76250661-76250741 2.52e-01 80 chr2:200775951-200776031 4.62e-03 67_[+2(4.09e-05)]_5 chr13:32889533-32889613 1.83e-02 80 chr19:1241639-1241719 2.98e-03 80 chr11:112097145-11209722 8.87e-01 80 chr6:117996507-117996587 3.19e-01 80 chr17:2615147-2615227 7.07e-01 80 chr19:1205637-1205717 8.01e-01 80 chrX:55026680-55026760 3.33e-02 34_[+1(8.30e-05)]_38 chr18:9102625-9102705 7.73e-01 80 chrX:40440077-40440157 2.39e-01 80 chr10:104159374-10415945 5.69e-01 80 chr6:105307751-105307831 8.70e-01 80 chr7:66205567-66205647 3.03e-01 80 chr3:10183471-10183551 9.40e-01 80 chr17:42144053-42144133 6.63e-03 80 chr2:30670112-30670192 4.10e-01 80 chr9:101984299-101984379 9.02e-03 37_[+3(3.23e-05)]_35 chr11:57435219-57435299 8.25e-03 1_[+5(1.94e-05)]_71 chr11:129765327-12976540 1.65e-01 80 chr19:2841083-2841163 9.62e-01 80 chr16:31119647-31119727 1.18e-03 18_[+4(8.04e-06)]_29_[+2(9.44e-05)]_\ 17 chr12:64616039-64616119 4.58e-03 60_[+1(4.20e-05)]_12 chr10:2357320-2357400 2.98e-01 80 chr3:49711215-49711295 1.00e+00 80 chr17:15902960-15903040 1.99e-02 57_[+2(4.09e-05)]_15 chr19:12917280-12917360 1.44e-04 10_[+4(1.98e-06)]_62 chr14:50329577-50329657 4.52e-03 32_[+2(1.74e-05)]_40 chr3:81810612-81810692 9.50e-01 80 chr5:157286130-157286210 3.48e-01 80 chr16:838717-838797 7.85e-01 80 chr11:134123311-13412339 2.28e-01 80 chr15:72766564-72766644 4.57e-01 80 chrX:119384639-119384719 6.47e-01 80 chr14:65569231-65569311 8.92e-01 80 chr19:19887277-19887357 2.21e-02 41_[+4(8.04e-06)]_31 chr19:12893310-12893390 1.55e-03 47_[+1(4.20e-05)]_25 chr7:17980089-17980169 1.17e-01 80 chr9:139760791-139760871 8.38e-01 80 chr13:73301846-73301926 3.96e-01 80 chr15:41709073-41709153 5.95e-01 80 chr8:135724884-135724964 4.87e-01 80 chr4:100485118-100485198 1.79e-04 34_[+3(2.85e-05)]_[+4(1.01e-05)]_30 chr12:57081999-57082079 1.49e-03 39_[+1(4.20e-05)]_33 chr17:18086358-18086438 8.70e-01 80 chr17:1619547-1619627 8.18e-01 80 chr7:102004265-102004345 3.05e-03 18_[+1(4.20e-05)]_6_[+1(4.20e-05)]_\ 40 chr3:122102957-122103037 9.96e-02 80 chr10:120840414-12084049 5.62e-02 80 chr16:2802506-2802586 7.02e-03 15_[+3(9.49e-06)]_57 chr13:28024541-28024621 9.61e-01 80 chr4:90032687-90032767 9.55e-01 80 chr8:101734401-101734481 1.19e-01 49_[+3(1.31e-05)]_23 chr2:128568695-128568775 9.66e-01 80 chr9:7799779-7799859 5.15e-01 80 chr10:27444194-27444274 1.52e-02 50_[+2(8.92e-06)]_22 chr6:101329203-101329283 3.48e-01 80 chr3:156544018-156544098 3.23e-02 53_[+2(4.09e-05)]_19 chrX:48755057-48755137 7.92e-01 80 chr2:32288546-32288626 7.99e-04 50_[+3(7.75e-06)]_22 chr9:99616857-99616937 1.95e-04 13_[+4(4.04e-06)]_59 chr9:37422609-37422689 2.51e-01 80 chr12:121837786-12183786 8.90e-01 80 chr19:58919880-58919960 9.94e-01 80 chr19:52552087-52552167 6.54e-01 80 chr5:76326128-76326208 3.09e-01 80 chr19:2163667-2163747 1.00e+00 80 chr1:17338480-17338560 9.92e-01 80 chr6:30294952-30295032 2.32e-01 80 chr5:154238083-154238163 5.78e-01 80 chr21:46859277-46859357 1.06e-01 80 chr20:37377012-37377092 4.06e-02 34_[+2(4.09e-05)]_38 chr21:38446137-38446217 4.11e-01 80 chr5:1799970-1800050 5.23e-01 80 chr10:13203477-13203557 3.10e-04 43_[+1(8.30e-05)]_[+2(8.92e-06)]_21 chr6:74171438-74171518 4.38e-01 80 chr20:20693560-20693640 9.48e-01 80 -------------------------------------------------------------------------------- ******************************************************************************** ******************************************************************************** Stopped because requested number of motifs (5) found. ******************************************************************************** CPU: c22n10.farnam.hpc.yale.internal ********************************************************************************