******************************************************************************** MEME - Motif discovery tool ******************************************************************************** MEME version 5.3.3 (Release date: Sun Feb 7 15:39:52 2021 -0800) For further information on how to interpret these results please access https://meme-suite.org/meme. To get a copy of the MEME Suite software please access https://meme-suite.org. ******************************************************************************** ******************************************************************************** REFERENCE ******************************************************************************** If you use this program in your research, please cite: Timothy L. Bailey and Charles Elkan, "Fitting a mixture model by expectation maximization to discover motifs in biopolymers", Proceedings of the Second International Conference on Intelligent Systems for Molecular Biology, pp. 28-36, AAAI Press, Menlo Park, California, 1994. ******************************************************************************** ******************************************************************************** TRAINING SET ******************************************************************************** PRIMARY SEQUENCES= ../result/final_prediction/K562/fasta/RankLinear0.6_40/FUS.fasta CONTROL SEQUENCES= --none-- ALPHABET= ACGT Sequence name Weight Length Sequence name Weight Length ------------- ------ ------ ------------- ------ ------ chr13:91705145-91705225 1.0000 80 chr3:159943201-159943281 1.0000 80 chr6:27859552-27859632 1.0000 80 chr11:65269783-65269863 1.0000 80 chr6:133141001-133141081 1.0000 80 chr13:91851047-91851127 1.0000 80 chr2:38977647-38977727 1.0000 80 chr1:25943546-25943626 1.0000 80 chr6:27834127-27834207 1.0000 80 chr13:81431297-81431377 1.0000 80 chr21:46929850-46929930 1.0000 80 chr17:45214175-45214255 1.0000 80 chr2:65658141-65658221 1.0000 80 chr9:139559964-139560044 1.0000 80 chr7:151145473-151145553 1.0000 80 chr5:137806411-137806491 1.0000 80 chr6:26159024-26159104 1.0000 80 chr9:139568266-139568346 1.0000 80 chr9:139617861-139617941 1.0000 80 chr19:10224820-10224900 1.0000 80 chr5:176831151-176831231 1.0000 80 chr13:91742081-91742161 1.0000 80 chr6:1605022-1605102 1.0000 80 chr13:91558554-91558634 1.0000 80 chr20:62328310-62328390 1.0000 80 chr1:145078339-145078419 1.0000 80 chr2:64371032-64371112 1.0000 80 chr21:43373694-43373774 1.0000 80 chr12:6977100-6977180 1.0000 80 chr10:79685931-79686011 1.0000 80 chr11:65271227-65271307 1.0000 80 chr17:57922062-57922142 1.0000 80 chr9:139560641-139560721 1.0000 80 chr11:65272693-65272773 1.0000 80 chr6:17600852-17600932 1.0000 80 chr10:6019213-6019293 1.0000 80 chr7:26228827-26228907 1.0000 80 chr22:22862981-22863061 1.0000 80 chr1:87170470-87170550 1.0000 80 chr16:89788349-89788429 1.0000 80 chr11:64808846-64808926 1.0000 80 chr17:45214377-45214457 1.0000 80 chr11:65196017-65196097 1.0000 80 chr4:6676021-6676101 1.0000 80 chr14:24550576-24550656 1.0000 80 chr2:55450627-55450707 1.0000 80 chr17:80055269-80055349 1.0000 80 chr11:118965290-11896537 1.0000 80 chr5:56205446-56205526 1.0000 80 chr18:9959698-9959778 1.0000 80 chr20:31171039-31171119 1.0000 80 chr6:26215974-26216054 1.0000 80 chr7:44788609-44788689 1.0000 80 chr13:90638424-90638504 1.0000 80 chr6:27102248-27102328 1.0000 80 chr10:12171647-12171727 1.0000 80 chr1:38274208-38274288 1.0000 80 chr19:10196889-10196969 1.0000 80 chr9:139562800-139562880 1.0000 80 chr11:62608344-62608424 1.0000 80 chr3:183959390-183959470 1.0000 80 chr7:26227928-26228008 1.0000 80 chr7:128865053-128865133 1.0000 80 chr1:28837736-28837816 1.0000 80 chr1:51984444-51984524 1.0000 80 chr17:79875840-79875920 1.0000 80 chr22:19706328-19706408 1.0000 80 chr7:156685718-156685798 1.0000 80 chr6:26198447-26198527 1.0000 80 chr16:2204930-2205010 1.0000 80 chr1:234744654-234744734 1.0000 80 chr17:40464494-40464574 1.0000 80 chr1:145115422-145115502 1.0000 80 chr6:37144530-37144610 1.0000 80 chr9:131451529-131451609 1.0000 80 chr4:100867993-100868073 1.0000 80 chr6:160390496-160390576 1.0000 80 chr19:54695191-54695271 1.0000 80 chr6:43478098-43478178 1.0000 80 chr8:145734987-145735067 1.0000 80 chr7:23509193-23509273 1.0000 80 chr17:74732893-74732973 1.0000 80 chr20:62670080-62670160 1.0000 80 chr6:26232406-26232486 1.0000 80 chr3:152880202-152880282 1.0000 80 chr6:133139736-133139816 1.0000 80 chr7:100033567-100033647 1.0000 80 chr19:13266458-13266538 1.0000 80 chr10:70320529-70320609 1.0000 80 chr6:26159953-26160033 1.0000 80 chr13:93194125-93194205 1.0000 80 chr16:3019889-3019969 1.0000 80 chr19:18264005-18264085 1.0000 80 chr1:113217705-113217785 1.0000 80 chr2:183902938-183903018 1.0000 80 chr6:64283054-64283134 1.0000 80 chr13:93271397-93271477 1.0000 80 chr17:40831917-40831997 1.0000 80 chr6:17601052-17601132 1.0000 80 chr15:40583377-40583457 1.0000 80 chr1:23857364-23857444 1.0000 80 chrX:153191580-153191660 1.0000 80 chr19:49995758-49995838 1.0000 80 chr5:137804099-137804179 1.0000 80 chr7:100027792-100027872 1.0000 80 chr6:20402546-20402626 1.0000 80 chr6:2971494-2971574 1.0000 80 chr17:2296285-2296365 1.0000 80 chr16:2198821-2198901 1.0000 80 chr19:813241-813321 1.0000 80 chrX:3733738-3733818 1.0000 80 chr5:131705438-131705518 1.0000 80 chr19:5692008-5692088 1.0000 80 chr1:17222996-17223076 1.0000 80 chr10:121302609-12130268 1.0000 80 chr1:178694321-178694401 1.0000 80 chr13:91279359-91279439 1.0000 80 chr14:50863531-50863611 1.0000 80 chr16:67063530-67063610 1.0000 80 chr16:67189380-67189460 1.0000 80 chr17:73584944-73585024 1.0000 80 chr8:91658389-91658469 1.0000 80 chr8:22462539-22462619 1.0000 80 chr1:46050082-46050162 1.0000 80 chr12:90102296-90102376 1.0000 80 chr7:99756035-99756115 1.0000 80 chr6:33588647-33588727 1.0000 80 chr1:36348636-36348716 1.0000 80 chr1:149856984-149857064 1.0000 80 chr22:50689656-50689736 1.0000 80 chr5:141488498-141488578 1.0000 80 chr9:135996347-135996427 1.0000 80 chr4:187644787-187644867 1.0000 80 chr16:66638849-66638929 1.0000 80 chr6:2245684-2245764 1.0000 80 chr18:12308535-12308615 1.0000 80 chr19:14142616-14142696 1.0000 80 chr11:65625051-65625131 1.0000 80 chr19:1248343-1248423 1.0000 80 chr6:26205828-26205908 1.0000 80 chr5:137805060-137805140 1.0000 80 chr9:130693020-130693100 1.0000 80 chr1:1057676-1057756 1.0000 80 chr10:65281232-65281312 1.0000 80 chr1:246887779-246887859 1.0000 80 chr17:48943245-48943325 1.0000 80 chr20:32251387-32251467 1.0000 80 chr2:54198010-54198090 1.0000 80 chr12:110719491-11071957 1.0000 80 chr6:74230168-74230248 1.0000 80 chr21:34852117-34852197 1.0000 80 chr13:90452729-90452809 1.0000 80 chr5:139028003-139028083 1.0000 80 chr17:19912915-19912995 1.0000 80 chr1:202927319-202927399 1.0000 80 chr6:158981432-158981512 1.0000 80 chr16:58549684-58549764 1.0000 80 chr1:877202-877282 1.0000 80 chr9:5832953-5833033 1.0000 80 chr7:30068100-30068180 1.0000 80 chr20:35234311-35234391 1.0000 80 chr4:37687825-37687905 1.0000 80 chr10:72575683-72575763 1.0000 80 chr6:86351967-86352047 1.0000 80 chr2:232574160-232574240 1.0000 80 chr7:158598742-158598822 1.0000 80 chr19:46388986-46389066 1.0000 80 chr6:26031517-26031597 1.0000 80 chr1:150521622-150521702 1.0000 80 chr19:13953439-13953519 1.0000 80 chr21:38338823-38338903 1.0000 80 chr1:26437767-26437847 1.0000 80 chr19:1445320-1445400 1.0000 80 chr19:868210-868290 1.0000 80 chr8:101964087-101964167 1.0000 80 chr8:146012541-146012621 1.0000 80 chr9:111881816-111881896 1.0000 80 chr2:73339755-73339835 1.0000 80 chr7:127032214-127032294 1.0000 80 chr12:39836776-39836856 1.0000 80 chr19:33183328-33183408 1.0000 80 chr2:65283719-65283799 1.0000 80 chr1:28837174-28837254 1.0000 80 chr22:29999675-29999755 1.0000 80 chr6:27115407-27115487 1.0000 80 chr6:37138275-37138355 1.0000 80 chr19:982836-982916 1.0000 80 chr6:160114226-160114306 1.0000 80 chr10:11865499-11865579 1.0000 80 chr1:233463875-233463955 1.0000 80 chr1:65432026-65432106 1.0000 80 chr16:402039-402119 1.0000 80 chr1:234746665-234746745 1.0000 80 chr1:145443101-145443181 1.0000 80 chr20:61557833-61557913 1.0000 80 chr2:61293106-61293186 1.0000 80 chrX:41193801-41193881 1.0000 80 chr16:66730260-66730340 1.0000 80 chr20:62152476-62152556 1.0000 80 chr1:201952149-201952229 1.0000 80 chr17:1552795-1552875 1.0000 80 chr10:65281461-65281541 1.0000 80 chr8:62626946-62627026 1.0000 80 chr21:46494936-46495016 1.0000 80 chr1:169862622-169862702 1.0000 80 chr9:139440751-139440831 1.0000 80 chr5:90678423-90678503 1.0000 80 chr3:33155643-33155723 1.0000 80 chr6:26198064-26198144 1.0000 80 chr18:23806741-23806821 1.0000 80 chr19:806151-806231 1.0000 80 chr18:34408878-34408958 1.0000 80 chr4:99917335-99917415 1.0000 80 chr10:23344503-23344583 1.0000 80 chr4:40057630-40057710 1.0000 80 chr19:17000802-17000882 1.0000 80 chr1:23346168-23346248 1.0000 80 chr16:31153910-31153990 1.0000 80 chr16:11836452-11836532 1.0000 80 chr10:49732443-49732523 1.0000 80 chr12:112856883-11285696 1.0000 80 chr10:22629804-22629884 1.0000 80 chr7:35734501-35734581 1.0000 80 chr16:84733931-84734011 1.0000 80 chr10:43892466-43892546 1.0000 80 chr10:35415942-35416022 1.0000 80 chr11:9025434-9025514 1.0000 80 chr16:31191892-31191972 1.0000 80 chr1:173991241-173991321 1.0000 80 chr18:24890941-24891021 1.0000 80 chr7:91763408-91763488 1.0000 80 chr15:90744719-90744799 1.0000 80 chr17:79818256-79818336 1.0000 80 chr6:151774708-151774788 1.0000 80 chr1:149859330-149859410 1.0000 80 chr22:19711738-19711818 1.0000 80 chr1:36621829-36621909 1.0000 80 chr8:144373464-144373544 1.0000 80 chr3:183415815-183415895 1.0000 80 chr19:10341846-10341926 1.0000 80 chr16:85587026-85587106 1.0000 80 chr11:46414007-46414087 1.0000 80 chr22:20849723-20849803 1.0000 80 chr11:65270904-65270984 1.0000 80 chr8:21999224-21999304 1.0000 80 chr19:56154217-56154297 1.0000 80 chr6:166796416-166796496 1.0000 80 chr19:1491130-1491210 1.0000 80 chr18:60190060-60190140 1.0000 80 chr19:12904525-12904605 1.0000 80 ******************************************************************************** ******************************************************************************** COMMAND LINE SUMMARY ******************************************************************************** This information can also be useful in the event you wish to report a problem with the MEME software. command: meme -oc ../result/final_prediction/K562/inference_raw/MEME/RankLinear0.6_40_FUS/ -dna -nmotifs 5 -w 8 -maxsize 250000 -nostatus ../result/final_prediction/K562/fasta/RankLinear0.6_40/FUS.fasta model: mod= zoops nmotifs= 5 evt= inf objective function: em= E-value of product of p-values starts= E-value of product of p-values strands: + width: minw= 8 maxw= 8 nsites: minsites= 2 maxsites= 250 wnsites= 0.8 theta: spmap= uni spfuzz= 0.5 em: prior= dirichlet b= 0.01 maxiter= 50 distance= 1e-05 trim: wg= 11 ws= 1 endgaps= yes data: n= 20000 N= 250 sample: seed= 0 hsfrac= 0 searchsize= 20000 norand= no csites= 1000 Letter frequencies in dataset: A 0.16 C 0.339 G 0.345 T 0.156 Background letter frequencies (from file dataset with add-one prior applied): A 0.16 C 0.339 G 0.345 T 0.156 Background model order: 0 ******************************************************************************** ******************************************************************************** MOTIF TTKTAWWT MEME-1 width = 8 sites = 35 llr = 324 E-value = 2.7e-017 ******************************************************************************** -------------------------------------------------------------------------------- Motif TTKTAWWT MEME-1 Description -------------------------------------------------------------------------------- Simplified A 31137661 pos.-specific C ::1::::: probability G ::5::::: matrix T 79373449 bits 2.7 2.4 2.1 * * 1.9 ** ** * Relative 1.6 ** ***** Entropy 1.3 ** ***** (13.3 bits) 1.1 ** ***** 0.8 ** ***** 0.5 ******** 0.3 ******** 0.0 -------- Multilevel TTGTAAAT consensus A TATTT sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTKTAWWT MEME-1 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr1:145115422-145115502 7 3.78e-07 actagg ttttaaat aggttacatg chr11:65196017-65196097 24 3.78e-07 atacgatatg ttttaaat gttcgtattt chr13:81431297-81431377 45 3.78e-07 TCTTTGTTGG TTTTAAAT GAACTTCACC chr6:26159024-26159104 27 1.95e-06 ACTGAAAGTA TTGTAAAT GTACAGCTCT chr13:91851047-91851127 70 3.13e-06 ACCAATTTAG TTGTAATT GAC chr13:91279359-91279439 15 4.72e-06 ATTGTTACTT TTTAAAAT AGCATTTTGT chr6:26198447-26198527 61 4.72e-06 GCATTGATCG ATTTAAAT TACATGTGAC chr17:57922062-57922142 65 4.72e-06 AAAGATATAT TTTAAAAT GCTTTCTT chr13:91742081-91742161 72 9.48e-06 GACAGTACAG ATGTAAAT A chr6:26198064-26198144 73 1.35e-05 aaaGCCAAAT TTATAAAT chr6:26205828-26205908 34 1.35e-05 accctaaagc ttgaaatt tagcatttat chr6:133139736-133139816 25 1.35e-05 TGTGTTAACA TTGAAATT GTCAACCTCA chr13:93194125-93194205 9 1.67e-05 agacatta tttttttt acttcattcc chr7:26228827-26228907 73 1.67e-05 TAAGCCTATG TTGAATAT chr13:91558554-91558634 45 2.18e-05 gatgcagaaa atgtattt aatgaaacaa chr18:24890941-24891021 14 2.46e-05 gtggatatac ttgttttt ctctcagtct chr1:145443101-145443181 55 2.46e-05 gtgtatgtgt ttgttttt tctacgctca chr6:26232406-26232486 68 2.46e-05 acaaagtgat atgaaaat atcta chr11:65271227-65271307 57 2.46e-05 GGAAAGACAA ATTTTATT CTTCATAAAG chr6:27834127-27834207 56 3.06e-05 GTTGATAGCA TATTATAT TAATGCCGAA chr6:26215974-26216054 14 3.62e-05 ggttagcttc attttttt gcagagacga chr6:151774708-151774788 71 4.06e-05 AGTTACAATC TAGTAATT TA chr1:28837736-28837816 35 4.06e-05 cctcatagag ttgtaata aggacaaagg chr6:27115407-27115487 56 4.55e-05 TTTACAATGT TTCTAAAT TAACCCACTG chr1:145078339-145078419 6 4.82e-05 tgtat atatatat agtcatgcaa chr19:49995758-49995838 22 5.58e-05 AGCTGTCTCA TTCTAATT CAGCTGCAAA chr13:90638424-90638504 18 5.58e-05 cccagtatga tagtattt ggaggtgagg chr17:45214377-45214457 53 5.58e-05 AACCAAATTC ATGATAAT AAAGAGCTAT chr11:65269783-65269863 70 5.58e-05 ATGGTAGCTT TTGTATTA TCA chr5:137804099-137804179 12 6.32e-05 CCTTCAATGC TAGAAAAT CGAGTTGGCA chr6:26031517-26031597 64 8.95e-05 TCTTACAAAG TTGTTTAA ACAAATGCT chr13:91705145-91705225 12 1.07e-04 aaaatggggc aataatat agacactgca chr10:23344503-23344583 59 1.14e-04 CTATTCTCTC ATTTTTAA GGGAGTCACA chr6:27859552-27859632 44 1.14e-04 GGTTCTGGTA TTGATAAA GACCCATAAA chr13:93271397-93271477 37 1.64e-04 ATGCATGGAG ATAATTTT CTGAGAAATA -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTKTAWWT MEME-1 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr1:145115422-145115502 3.8e-07 6_[+1]_66 chr11:65196017-65196097 3.8e-07 23_[+1]_49 chr13:81431297-81431377 3.8e-07 44_[+1]_28 chr6:26159024-26159104 2e-06 26_[+1]_46 chr13:91851047-91851127 3.1e-06 69_[+1]_3 chr13:91279359-91279439 4.7e-06 14_[+1]_58 chr6:26198447-26198527 4.7e-06 60_[+1]_12 chr17:57922062-57922142 4.7e-06 64_[+1]_8 chr13:91742081-91742161 9.5e-06 71_[+1]_1 chr6:26198064-26198144 1.3e-05 72_[+1] chr6:26205828-26205908 1.3e-05 33_[+1]_39 chr6:133139736-133139816 1.3e-05 24_[+1]_48 chr13:93194125-93194205 1.7e-05 8_[+1]_64 chr7:26228827-26228907 1.7e-05 72_[+1] chr13:91558554-91558634 2.2e-05 44_[+1]_28 chr18:24890941-24891021 2.5e-05 13_[+1]_59 chr1:145443101-145443181 2.5e-05 54_[+1]_18 chr6:26232406-26232486 2.5e-05 67_[+1]_5 chr11:65271227-65271307 2.5e-05 56_[+1]_16 chr6:27834127-27834207 3.1e-05 55_[+1]_17 chr6:26215974-26216054 3.6e-05 13_[+1]_59 chr6:151774708-151774788 4.1e-05 70_[+1]_2 chr1:28837736-28837816 4.1e-05 34_[+1]_38 chr6:27115407-27115487 4.5e-05 55_[+1]_17 chr1:145078339-145078419 4.8e-05 5_[+1]_67 chr19:49995758-49995838 5.6e-05 21_[+1]_51 chr13:90638424-90638504 5.6e-05 17_[+1]_55 chr17:45214377-45214457 5.6e-05 52_[+1]_20 chr11:65269783-65269863 5.6e-05 69_[+1]_3 chr5:137804099-137804179 6.3e-05 11_[+1]_61 chr6:26031517-26031597 9e-05 63_[+1]_9 chr13:91705145-91705225 0.00011 11_[+1]_61 chr10:23344503-23344583 0.00011 58_[+1]_14 chr6:27859552-27859632 0.00011 43_[+1]_29 chr13:93271397-93271477 0.00016 36_[+1]_36 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTKTAWWT MEME-1 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF TTKTAWWT width=8 seqs=35 chr1:145115422-145115502 ( 7) TTTTAAAT 1 chr11:65196017-65196097 ( 24) TTTTAAAT 1 chr13:81431297-81431377 ( 45) TTTTAAAT 1 chr6:26159024-26159104 ( 27) TTGTAAAT 1 chr13:91851047-91851127 ( 70) TTGTAATT 1 chr13:91279359-91279439 ( 15) TTTAAAAT 1 chr6:26198447-26198527 ( 61) ATTTAAAT 1 chr17:57922062-57922142 ( 65) TTTAAAAT 1 chr13:91742081-91742161 ( 72) ATGTAAAT 1 chr6:26198064-26198144 ( 73) TTATAAAT 1 chr6:26205828-26205908 ( 34) TTGAAATT 1 chr6:133139736-133139816 ( 25) TTGAAATT 1 chr13:93194125-93194205 ( 9) TTTTTTTT 1 chr7:26228827-26228907 ( 73) TTGAATAT 1 chr13:91558554-91558634 ( 45) ATGTATTT 1 chr18:24890941-24891021 ( 14) TTGTTTTT 1 chr1:145443101-145443181 ( 55) TTGTTTTT 1 chr6:26232406-26232486 ( 68) ATGAAAAT 1 chr11:65271227-65271307 ( 57) ATTTTATT 1 chr6:27834127-27834207 ( 56) TATTATAT 1 chr6:26215974-26216054 ( 14) ATTTTTTT 1 chr6:151774708-151774788 ( 71) TAGTAATT 1 chr1:28837736-28837816 ( 35) TTGTAATA 1 chr6:27115407-27115487 ( 56) TTCTAAAT 1 chr1:145078339-145078419 ( 6) ATATATAT 1 chr19:49995758-49995838 ( 22) TTCTAATT 1 chr13:90638424-90638504 ( 18) TAGTATTT 1 chr17:45214377-45214457 ( 53) ATGATAAT 1 chr11:65269783-65269863 ( 70) TTGTATTA 1 chr5:137804099-137804179 ( 12) TAGAAAAT 1 chr6:26031517-26031597 ( 64) TTGTTTAA 1 chr13:91705145-91705225 ( 12) AATAATAT 1 chr10:23344503-23344583 ( 59) ATTTTTAA 1 chr6:27859552-27859632 ( 44) TTGATAAA 1 chr13:93271397-93271477 ( 37) ATAATTTT 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTKTAWWT MEME-1 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 11.0506 E= 2.7e-017 97 -1177 -1177 214 -17 -1177 -1177 246 -90 -257 58 114 97 -1177 -1177 214 216 -1177 -1177 88 190 -1177 -1177 136 183 -1177 -1177 146 -17 -1177 -1177 246 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTKTAWWT MEME-1 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 35 E= 2.7e-017 0.314286 0.000000 0.000000 0.685714 0.142857 0.000000 0.000000 0.857143 0.085714 0.057143 0.514286 0.342857 0.314286 0.000000 0.000000 0.685714 0.714286 0.000000 0.000000 0.285714 0.600000 0.000000 0.000000 0.400000 0.571429 0.000000 0.000000 0.428571 0.142857 0.000000 0.000000 0.857143 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTKTAWWT MEME-1 regular expression -------------------------------------------------------------------------------- [TA]T[GT][TA][AT][AT][AT]T -------------------------------------------------------------------------------- Time 5.14 secs. ******************************************************************************** ******************************************************************************** MOTIF AAVARAAA MEME-2 width = 8 sites = 27 llr = 240 E-value = 2.7e-003 ******************************************************************************** -------------------------------------------------------------------------------- Motif AAVARAAA MEME-2 Description -------------------------------------------------------------------------------- Simplified A 8a394967 pos.-specific C ::31::1: probability G ::4:41:: matrix T 2:::1:23 bits 2.7 * 2.4 * 2.1 * * * 1.9 ** * * * Relative 1.6 ** * * * Entropy 1.3 ** * * * (12.8 bits) 1.1 ** * *** 0.8 ** ***** 0.5 ** ***** 0.3 ******** 0.0 -------- Multilevel AAGAAAAA consensus T A G TT sequence C -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAVARAAA MEME-2 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr6:26198064-26198144 50 4.29e-07 TGCTGTaaaa aaaaaaaa aaaaaaaaGC chr18:9959698-9959778 39 4.29e-07 aaaaaaaaaa aaaaaaaa TGTGGAGGGT chr17:45214175-45214255 35 1.36e-06 TCGGTGTTCG AAGAAAAA GCAACAAAGT chr11:65196017-65196097 42 3.61e-06 gttcgtattt aacaaaAA CATACTGACA chr6:27859552-27859632 65 3.61e-06 CCATAAAGAC AACAAAAA GGTTAGTT chr10:23344503-23344583 21 6.44e-06 TCTCCAGTAA AAGAGAAA AAGAGGAAGG chr2:232574160-232574240 45 6.44e-06 GCAGGGAGGA AAGAGAAA GTGAAGCGCG chr7:26228827-26228907 25 6.44e-06 CAATTTCTAC AAGAGAAA CAGCTCAACA chr13:91558554-91558634 16 6.44e-06 gcatcccaga aagagaaa agacaggaaa chr6:151774708-151774788 49 7.77e-06 AAACCTTTTG AAGAAATA CCCAAGTTAC chr6:26205828-26205908 2 1.42e-05 t aaaagaat ttgactctct chr13:90452729-90452809 28 2.00e-05 tgtggttata tacaaaaa atctctgacc chr1:28837736-28837816 67 3.85e-05 ggtatttgtg aaAAGATT CTTAGG chr17:57922062-57922142 56 3.85e-05 TCCAGAAACA AAGATATA TTTTAAAATG chr7:91763408-91763488 63 4.77e-05 ACTCAGACCC TAAAGAAT GTACGTACCA chr13:93271397-93271477 73 4.77e-05 GATTAGTTCT AACAAATT chr6:26159953-26160033 24 5.09e-05 TGCCCTCATA AACAAACA CGAAATGATG chr5:137805060-137805140 17 6.67e-05 ACTTGGCCTT TAGAGATA CAAGGATCCT chr13:91279359-91279439 59 6.67e-05 ATATAAAATT AAGAGACA ATAGGAAATA chr16:2204930-2205010 9 7.12e-05 TCAGCGCC AAAATACA GACATTAAGT chr11:65269783-65269863 4 1.06e-04 TAC TATAGAAA CTGCAGAGCA chr1:28837174-28837254 50 1.12e-04 GAATCCCAGG AACCAAAA GACTAATTGT chr17:45214377-45214457 73 1.19e-04 AGAGCTATCT AACAAGAA chr19:10196889-10196969 63 1.37e-04 CCTGAATCGA AAGCGAAA CAGGGGCCGG chr13:93194125-93194205 56 1.49e-04 attaaatgac taaatatt tgtaggtcta chr1:17222996-17223076 62 1.62e-04 TAGAGCCAGG TAGAAACT ACGCAGATGG chr18:24890941-24891021 38 2.09e-04 gtcttagggg aaaaggat tcaatctttc -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAVARAAA MEME-2 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr6:26198064-26198144 4.3e-07 49_[+2]_23 chr18:9959698-9959778 4.3e-07 38_[+2]_34 chr17:45214175-45214255 1.4e-06 34_[+2]_38 chr11:65196017-65196097 3.6e-06 41_[+2]_31 chr6:27859552-27859632 3.6e-06 64_[+2]_8 chr10:23344503-23344583 6.4e-06 20_[+2]_52 chr2:232574160-232574240 6.4e-06 44_[+2]_28 chr7:26228827-26228907 6.4e-06 24_[+2]_48 chr13:91558554-91558634 6.4e-06 15_[+2]_57 chr6:151774708-151774788 7.8e-06 48_[+2]_24 chr6:26205828-26205908 1.4e-05 1_[+2]_71 chr13:90452729-90452809 2e-05 27_[+2]_45 chr1:28837736-28837816 3.9e-05 66_[+2]_6 chr17:57922062-57922142 3.9e-05 55_[+2]_17 chr7:91763408-91763488 4.8e-05 62_[+2]_10 chr13:93271397-93271477 4.8e-05 72_[+2] chr6:26159953-26160033 5.1e-05 23_[+2]_49 chr5:137805060-137805140 6.7e-05 16_[+2]_56 chr13:91279359-91279439 6.7e-05 58_[+2]_14 chr16:2204930-2205010 7.1e-05 8_[+2]_64 chr11:65269783-65269863 0.00011 3_[+2]_69 chr1:28837174-28837254 0.00011 49_[+2]_23 chr17:45214377-45214457 0.00012 72_[+2] chr19:10196889-10196969 0.00014 62_[+2]_10 chr13:93194125-93194205 0.00015 55_[+2]_17 chr1:17222996-17223076 0.00016 61_[+2]_11 chr18:24890941-24891021 0.00021 37_[+2]_35 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAVARAAA MEME-2 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF AAVARAAA width=8 seqs=27 chr6:26198064-26198144 ( 50) AAAAAAAA 1 chr18:9959698-9959778 ( 39) AAAAAAAA 1 chr17:45214175-45214255 ( 35) AAGAAAAA 1 chr11:65196017-65196097 ( 42) AACAAAAA 1 chr6:27859552-27859632 ( 65) AACAAAAA 1 chr10:23344503-23344583 ( 21) AAGAGAAA 1 chr2:232574160-232574240 ( 45) AAGAGAAA 1 chr7:26228827-26228907 ( 25) AAGAGAAA 1 chr13:91558554-91558634 ( 16) AAGAGAAA 1 chr6:151774708-151774788 ( 49) AAGAAATA 1 chr6:26205828-26205908 ( 2) AAAAGAAT 1 chr13:90452729-90452809 ( 28) TACAAAAA 1 chr1:28837736-28837816 ( 67) AAAAGATT 1 chr17:57922062-57922142 ( 56) AAGATATA 1 chr7:91763408-91763488 ( 63) TAAAGAAT 1 chr13:93271397-93271477 ( 73) AACAAATT 1 chr6:26159953-26160033 ( 24) AACAAACA 1 chr5:137805060-137805140 ( 17) TAGAGATA 1 chr13:91279359-91279439 ( 59) AAGAGACA 1 chr16:2204930-2205010 ( 9) AAAATACA 1 chr11:65269783-65269863 ( 4) TATAGAAA 1 chr1:28837174-28837254 ( 50) AACCAAAA 1 chr17:45214377-45214457 ( 73) AACAAGAA 1 chr19:10196889-10196969 ( 63) AAGCGAAA 1 chr13:93194125-93194205 ( 56) TAAATATT 1 chr1:17222996-17223076 ( 62) TAGAAACT 1 chr18:24890941-24891021 ( 38) AAAAGGAT 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAVARAAA MEME-2 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 11.0506 E= 2.7e-003 228 -1140 -1140 51 264 -1140 -1140 -1140 89 -39 24 -207 253 -219 -1140 -1140 147 -1140 36 -49 253 -1140 -222 -1140 197 -119 -1140 51 221 -1140 -1140 74 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAVARAAA MEME-2 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 27 E= 2.7e-003 0.777778 0.000000 0.000000 0.222222 1.000000 0.000000 0.000000 0.000000 0.296296 0.259259 0.407407 0.037037 0.925926 0.074074 0.000000 0.000000 0.444444 0.000000 0.444444 0.111111 0.925926 0.000000 0.074074 0.000000 0.629630 0.148148 0.000000 0.222222 0.740741 0.000000 0.000000 0.259259 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAVARAAA MEME-2 regular expression -------------------------------------------------------------------------------- [AT]A[GAC]A[AG]A[AT][AT] -------------------------------------------------------------------------------- Time 8.97 secs. ******************************************************************************** ******************************************************************************** MOTIF AAATAASW MEME-3 width = 8 sites = 14 llr = 141 E-value = 4.1e+000 ******************************************************************************** -------------------------------------------------------------------------------- Motif AAATAASW MEME-3 Description -------------------------------------------------------------------------------- Simplified A 9991aa13 pos.-specific C :1::::61 probability G :::1::31 matrix T 1:18:::5 bits 2.7 ** 2.4 ** 2.1 *** ** 1.9 *** ** Relative 1.6 ****** Entropy 1.3 ****** (14.5 bits) 1.1 ****** 0.8 ****** * 0.5 ****** * 0.3 ******** 0.0 -------- Multilevel AAATAACT consensus GA sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAATAASW MEME-3 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr13:91279359-91279439 72 8.65e-07 AGACAATAGG AAATAACT T chr6:27102248-27102328 54 8.65e-07 ACGGTAGTGC AAATAACT TTTGGTGTTG chr1:28837736-28837816 8 3.04e-06 gttcaca aaataagt gataaactac chr13:93271397-93271477 50 4.36e-06 ATTTTCTGAG AAATAAGA GTCAAGATTA chr13:91742081-91742161 20 6.09e-06 ATTTAGAATG AATTAACT GGAAGAATAG chr20:62152476-62152556 69 7.97e-06 CCGCCTCGGT AAATAACC CAGC chr17:45214175-45214255 70 1.06e-05 CTAAACAAAC AAAAAACA ACT chr13:91851047-91851127 43 1.06e-05 ATTGCTTCTT AATTAACA ATCCTTTTTA chr7:26228827-26228907 60 1.79e-05 TACACACAGG AAATAAGC CTATGTTGAA chr6:26198064-26198144 58 1.87e-05 aaaaaaaaaa aaaaaaaa GCCAAATTTA chr6:26232406-26232486 50 2.64e-05 aagacacctg taataagt acaaagtgat chr1:145115422-145115502 39 2.64e-05 gaccaatgtc acataact tgtacaggtg chr6:27859552-27859632 22 2.64e-05 TTAGTTGATC AAAGAACT ACCAGGTTCT chr13:91705145-91705225 57 2.82e-05 agagctggtc aaataaag gaataatcat -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAATAASW MEME-3 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr13:91279359-91279439 8.7e-07 71_[+3]_1 chr6:27102248-27102328 8.7e-07 53_[+3]_19 chr1:28837736-28837816 3e-06 7_[+3]_65 chr13:93271397-93271477 4.4e-06 49_[+3]_23 chr13:91742081-91742161 6.1e-06 19_[+3]_53 chr20:62152476-62152556 8e-06 68_[+3]_4 chr17:45214175-45214255 1.1e-05 69_[+3]_3 chr13:91851047-91851127 1.1e-05 42_[+3]_30 chr7:26228827-26228907 1.8e-05 59_[+3]_13 chr6:26198064-26198144 1.9e-05 57_[+3]_15 chr6:26232406-26232486 2.6e-05 49_[+3]_23 chr1:145115422-145115502 2.6e-05 38_[+3]_34 chr6:27859552-27859632 2.6e-05 21_[+3]_51 chr13:91705145-91705225 2.8e-05 56_[+3]_16 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAATAASW MEME-3 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF AAATAASW width=8 seqs=14 chr13:91279359-91279439 ( 72) AAATAACT 1 chr6:27102248-27102328 ( 54) AAATAACT 1 chr1:28837736-28837816 ( 8) AAATAAGT 1 chr13:93271397-93271477 ( 50) AAATAAGA 1 chr13:91742081-91742161 ( 20) AATTAACT 1 chr20:62152476-62152556 ( 69) AAATAACC 1 chr17:45214175-45214255 ( 70) AAAAAACA 1 chr13:91851047-91851127 ( 43) AATTAACA 1 chr7:26228827-26228907 ( 60) AAATAAGC 1 chr6:26198064-26198144 ( 58) AAAAAAAA 1 chr6:26232406-26232486 ( 50) TAATAAGT 1 chr1:145115422-145115502 ( 39) ACATAACT 1 chr6:27859552-27859632 ( 22) AAAGAACT 1 chr13:91705145-91705225 ( 57) AAATAAAG 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAATAASW MEME-3 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 10.9532 E= 4.1e+000 253 -1045 -1045 -112 253 -224 -1045 -1045 242 -1045 -1045 -12 -17 -1045 -227 234 264 -1045 -1045 -1045 264 -1045 -1045 -1045 -17 75 -27 -1045 83 -125 -227 168 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAATAASW MEME-3 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 14 E= 4.1e+000 0.928571 0.000000 0.000000 0.071429 0.928571 0.071429 0.000000 0.000000 0.857143 0.000000 0.000000 0.142857 0.142857 0.000000 0.071429 0.785714 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.142857 0.571429 0.285714 0.000000 0.285714 0.142857 0.071429 0.500000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAATAASW MEME-3 regular expression -------------------------------------------------------------------------------- AAATAA[CG][TA] -------------------------------------------------------------------------------- Time 12.74 secs. ******************************************************************************** ******************************************************************************** MOTIF TTWTYTYW MEME-4 width = 8 sites = 16 llr = 155 E-value = 1.5e+001 ******************************************************************************** -------------------------------------------------------------------------------- Motif TTWTYTYW MEME-4 Description -------------------------------------------------------------------------------- Simplified A ::5::::4 pos.-specific C ::::3:4: probability G :::32:2: matrix T aa575a46 bits 2.7 ** * 2.4 ** * 2.1 ** * 1.9 ** * Relative 1.6 *** * * Entropy 1.3 **** * * (13.9 bits) 1.1 **** * * 0.8 **** * * 0.5 ******** 0.3 ******** 0.0 -------- Multilevel TTATTTCT consensus TGC TA sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTWTYTYW MEME-4 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr13:91851047-91851127 7 1.44e-06 GAAAGG TTATTTTA AGAAAGGTTA chr6:151774708-151774788 5 2.98e-06 CAGT TTTTTTCT TAAAGTTCTA chr13:91742081-91742161 42 2.98e-06 GAATAGTTCG TTTTTTCT ACACATACAG chr13:81431297-81431377 30 2.98e-06 TTCTTGTTTA TTATTTCT TTGTTGGTTT chr6:26198064-26198144 4 6.11e-06 CTC TTATCTTT TACAAGTTCA chr13:91279359-91279439 27 1.74e-05 TAAAATAGCA TTTTGTTT CACCTATAAC chr11:65270904-65270984 40 1.90e-05 ACTAAGGAAA TTTGTTTA GCATTGAATC chr16:58549684-58549764 2 2.40e-05 C TTATCTCA GGTGGCGGGG chr6:26205828-26205908 48 2.40e-05 aatttagcat ttatctca catgagacaa chr13:93194125-93194205 37 2.40e-05 agtggcatgc ttatgtta gattaaatga chr13:93271397-93271477 65 2.75e-05 AGAGTCAAGA TTAGTTCT AACAAATT chr7:26227928-26228008 68 2.75e-05 CTCTGAACGA TTTGTTCT CTGTT chr6:27102248-27102328 18 4.13e-05 AGACTGGCAG TTTTCTGT AAAGGAGGGT chr6:133139736-133139816 54 4.82e-05 GTACTCTGGC TTTTCTGA GGAAAGTTCA chr6:26159024-26159104 44 7.31e-05 TGTACAGCTC TTTGGTTT CCGTGTGCAG chr6:27859552-27859632 12 7.31e-05 GATGGAGATT TTAGTTGA TCAAAGAACT -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTWTYTYW MEME-4 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr13:91851047-91851127 1.4e-06 6_[+4]_66 chr6:151774708-151774788 3e-06 4_[+4]_68 chr13:91742081-91742161 3e-06 41_[+4]_31 chr13:81431297-81431377 3e-06 29_[+4]_43 chr6:26198064-26198144 6.1e-06 3_[+4]_69 chr13:91279359-91279439 1.7e-05 26_[+4]_46 chr11:65270904-65270984 1.9e-05 39_[+4]_33 chr16:58549684-58549764 2.4e-05 1_[+4]_71 chr6:26205828-26205908 2.4e-05 47_[+4]_25 chr13:93194125-93194205 2.4e-05 36_[+4]_36 chr13:93271397-93271477 2.7e-05 64_[+4]_8 chr7:26227928-26228008 2.7e-05 67_[+4]_5 chr6:27102248-27102328 4.1e-05 17_[+4]_55 chr6:133139736-133139816 4.8e-05 53_[+4]_19 chr6:26159024-26159104 7.3e-05 43_[+4]_29 chr6:27859552-27859632 7.3e-05 11_[+4]_61 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTWTYTYW MEME-4 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF TTWTYTYW width=8 seqs=16 chr13:91851047-91851127 ( 7) TTATTTTA 1 chr6:151774708-151774788 ( 5) TTTTTTCT 1 chr13:91742081-91742161 ( 42) TTTTTTCT 1 chr13:81431297-81431377 ( 30) TTATTTCT 1 chr6:26198064-26198144 ( 4) TTATCTTT 1 chr13:91279359-91279439 ( 27) TTTTGTTT 1 chr11:65270904-65270984 ( 40) TTTGTTTA 1 chr16:58549684-58549764 ( 2) TTATCTCA 1 chr6:26205828-26205908 ( 48) TTATCTCA 1 chr13:93194125-93194205 ( 37) TTATGTTA 1 chr13:93271397-93271477 ( 65) TTAGTTCT 1 chr7:26227928-26228008 ( 68) TTTGTTCT 1 chr6:27102248-27102328 ( 18) TTTTCTGT 1 chr6:133139736-133139816 ( 54) TTTTCTGA 1 chr6:26159024-26159104 ( 44) TTTGGTTT 1 chr6:27859552-27859632 ( 12) TTAGTTGA 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTWTYTYW MEME-4 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 11.8922 E= 1.5e+001 -1064 -1064 -1064 268 -1064 -1064 -1064 268 164 -1064 -1064 168 -1064 -1064 -14 214 -1064 -12 -88 168 -1064 -1064 -1064 268 -1064 37 -88 127 145 -1064 -1064 185 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTWTYTYW MEME-4 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 16 E= 1.5e+001 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.500000 0.000000 0.000000 0.500000 0.000000 0.000000 0.312500 0.687500 0.000000 0.312500 0.187500 0.500000 0.000000 0.000000 0.000000 1.000000 0.000000 0.437500 0.187500 0.375000 0.437500 0.000000 0.000000 0.562500 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTWTYTYW MEME-4 regular expression -------------------------------------------------------------------------------- TT[AT][TG][TC]T[CT][TA] -------------------------------------------------------------------------------- Time 16.48 secs. ******************************************************************************** ******************************************************************************** MOTIF TATTTGTG MEME-5 width = 8 sites = 5 llr = 60 E-value = 1.0e+003 ******************************************************************************** -------------------------------------------------------------------------------- Motif TATTTGTG MEME-5 Description -------------------------------------------------------------------------------- Simplified A :82::::2 pos.-specific C :::::::: probability G :::::a:8 matrix T a28aa:a: bits 2.7 * ** * 2.4 * ** * 2.1 * ** * 1.9 ***** * Relative 1.6 ******* Entropy 1.3 ******* (17.2 bits) 1.1 ******** 0.8 ******** 0.5 ******** 0.3 ******** 0.0 -------- Multilevel TATTTGTG consensus TA A sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TATTTGTG MEME-5 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr6:26198064-26198144 27 1.76e-06 GTTCAACTGG TATTTGTG TAATCTGCTG chr1:28837736-28837816 59 1.76e-06 aaggagttgg tatttgtg aaAAGATTCT chr13:81431297-81431377 63 2.58e-06 GAACTTCACC TATTTGTA GACATAGTTT chr1:145443101-145443181 22 6.10e-06 tacgttcagt taattgtg tgtgcgtgtg chr13:90452729-90452809 14 6.10e-06 tttgcccgtg tttttgtg gttatataca -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TATTTGTG MEME-5 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr6:26198064-26198144 1.8e-06 26_[+5]_46 chr1:28837736-28837816 1.8e-06 58_[+5]_14 chr13:81431297-81431377 2.6e-06 62_[+5]_10 chr1:145443101-145443181 6.1e-06 21_[+5]_51 chr13:90452729-90452809 6.1e-06 13_[+5]_59 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TATTTGTG MEME-5 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF TATTTGTG width=8 seqs=5 chr6:26198064-26198144 ( 27) TATTTGTG 1 chr1:28837736-28837816 ( 59) TATTTGTG 1 chr13:81431297-81431377 ( 63) TATTTGTA 1 chr1:145443101-145443181 ( 22) TAATTGTG 1 chr13:90452729-90452809 ( 14) TTTTTGTG 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TATTTGTG MEME-5 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 12.0849 E= 1.0e+003 -897 -897 -897 268 232 -897 -897 36 32 -897 -897 236 -897 -897 -897 268 -897 -897 -897 268 -897 -897 153 -897 -897 -897 -897 268 32 -897 121 -897 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TATTTGTG MEME-5 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 5 E= 1.0e+003 0.000000 0.000000 0.000000 1.000000 0.800000 0.000000 0.000000 0.200000 0.200000 0.000000 0.000000 0.800000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.200000 0.000000 0.800000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TATTTGTG MEME-5 regular expression -------------------------------------------------------------------------------- T[AT][TA]TTGT[GA] -------------------------------------------------------------------------------- Time 20.18 secs. ******************************************************************************** ******************************************************************************** SUMMARY OF MOTIFS ******************************************************************************** -------------------------------------------------------------------------------- Combined block diagrams: non-overlapping sites with p-value < 0.0001 -------------------------------------------------------------------------------- SEQUENCE NAME COMBINED P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr13:91705145-91705225 5.73e-05 56_[+3(2.82e-05)]_16 chr3:159943201-159943281 9.99e-01 80 chr6:27859552-27859632 3.86e-08 11_[+4(7.31e-05)]_2_[+3(2.64e-05)]_\ 35_[+2(3.61e-06)]_8 chr11:65269783-65269863 7.86e-06 69_[+1(5.58e-05)]_3 chr6:133141001-133141081 2.34e-03 80 chr13:91851047-91851127 2.69e-10 6_[+4(1.44e-06)]_28_[+3(1.06e-05)]_\ 19_[+1(3.13e-06)]_3 chr2:38977647-38977727 1.00e+00 80 chr1:25943546-25943626 9.78e-01 80 chr6:27834127-27834207 9.48e-05 55_[+1(3.06e-05)]_17 chr13:81431297-81431377 1.10e-11 29_[+4(2.98e-06)]_7_[+1(3.78e-07)]_\ 10_[+5(2.58e-06)]_10 chr21:46929850-46929930 1.00e+00 80 chr17:45214175-45214255 6.10e-07 34_[+2(1.36e-06)]_11_[+3(7.65e-05)]_\ 5_[+2(3.61e-06)]_6 chr2:65658141-65658221 9.09e-01 80 chr9:139559964-139560044 1.00e+00 80 chr7:151145473-151145553 1.00e+00 80 chr5:137806411-137806491 4.79e-02 80 chr6:26159024-26159104 5.30e-07 26_[+1(1.95e-06)]_9_[+4(7.31e-05)]_\ 29 chr9:139568266-139568346 9.93e-01 80 chr9:139617861-139617941 1.00e+00 80 chr19:10224820-10224900 8.86e-01 80 chr5:176831151-176831231 9.85e-01 80 chr13:91742081-91742161 3.59e-09 19_[+3(6.09e-06)]_14_[+4(2.98e-06)]_\ 22_[+1(9.48e-06)]_1 chr6:1605022-1605102 9.99e-01 80 chr13:91558554-91558634 5.77e-06 15_[+2(6.44e-06)]_21_[+1(2.18e-05)]_\ 28 chr20:62328310-62328390 7.22e-01 80 chr1:145078339-145078419 1.45e-04 3_[+1(4.82e-05)]_69 chr2:64371032-64371112 1.00e+00 80 chr21:43373694-43373774 9.98e-01 80 chr12:6977100-6977180 1.00e+00 80 chr10:79685931-79686011 1.00e+00 80 chr11:65271227-65271307 3.15e-05 56_[+1(2.46e-05)]_16 chr17:57922062-57922142 9.94e-07 55_[+2(3.85e-05)]_1_[+1(4.72e-06)]_\ 8 chr9:139560641-139560721 1.00e+00 80 chr11:65272693-65272773 2.39e-02 80 chr6:17600852-17600932 9.99e-01 80 chr10:6019213-6019293 1.00e+00 80 chr7:26228827-26228907 1.37e-07 24_[+2(6.44e-06)]_11_[+2(5.93e-05)]_\ 8_[+3(1.79e-05)]_5_[+1(1.67e-05)] chr22:22862981-22863061 9.96e-01 80 chr1:87170470-87170550 1.00e+00 80 chr16:89788349-89788429 8.04e-01 80 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******************************************************************************** Stopped because requested number of motifs (5) found. ******************************************************************************** CPU: c22n06.farnam.hpc.yale.internal ********************************************************************************