******************************************************************************** MEME - Motif discovery tool ******************************************************************************** MEME version 5.3.3 (Release date: Sun Feb 7 15:39:52 2021 -0800) For further information on how to interpret these results please access https://meme-suite.org/meme. To get a copy of the MEME Suite software please access https://meme-suite.org. ******************************************************************************** ******************************************************************************** REFERENCE ******************************************************************************** If you use this program in your research, please cite: Timothy L. Bailey and Charles Elkan, "Fitting a mixture model by expectation maximization to discover motifs in biopolymers", Proceedings of the Second International Conference on Intelligent Systems for Molecular Biology, pp. 28-36, AAAI Press, Menlo Park, California, 1994. ******************************************************************************** ******************************************************************************** TRAINING SET ******************************************************************************** PRIMARY SEQUENCES= ../result/final_prediction/K562/fasta/RankLinear0.6_40/FOXK2.fasta CONTROL SEQUENCES= --none-- ALPHABET= ACGT Sequence name Weight Length Sequence name Weight Length ------------- ------ ------ ------------- ------ ------ chr1:167191643-167191723 1.0000 80 chr19:55185653-55185733 1.0000 80 chr1:25758761-25758841 1.0000 80 chr3:72201905-72201985 1.0000 80 chr8:356903-356983 1.0000 80 chr11:9952576-9952656 1.0000 80 chrX:152419857-152419937 1.0000 80 chr7:104909616-104909696 1.0000 80 chr14:52118269-52118349 1.0000 80 chr6:83073339-83073419 1.0000 80 chr12:120763373-12076345 1.0000 80 chrX:47880825-47880905 1.0000 80 chr7:99104180-99104260 1.0000 80 chr1:1624233-1624313 1.0000 80 chr11:66034861-66034941 1.0000 80 chr12:46979763-46979843 1.0000 80 chr7:44078884-44078964 1.0000 80 chr7:44152385-44152465 1.0000 80 chr8:17013341-17013421 1.0000 80 chr1:118277851-118277931 1.0000 80 chr9:135285399-135285479 1.0000 80 chr6:90650296-90650376 1.0000 80 chr12:56224449-56224529 1.0000 80 chr2:159216391-159216471 1.0000 80 chr2:175190702-175190782 1.0000 80 chr14:63568921-63569001 1.0000 80 chr17:62923807-62923887 1.0000 80 chr19:50268857-50268937 1.0000 80 chr15:50296034-50296114 1.0000 80 chr9:33375443-33375523 1.0000 80 chr2:86947255-86947335 1.0000 80 chr10:112201532-11220161 1.0000 80 chr14:21944642-21944722 1.0000 80 chr10:27099511-27099591 1.0000 80 chr5:150326181-150326261 1.0000 80 chr1:15946938-15947018 1.0000 80 chr8:95907968-95908048 1.0000 80 chr16:75682556-75682636 1.0000 80 chr9:33391526-33391606 1.0000 80 chrX:43513977-43514057 1.0000 80 chr9:140444849-140444929 1.0000 80 chr16:4511397-4511477 1.0000 80 chr19:35739421-35739501 1.0000 80 chrX:109473158-109473238 1.0000 80 chr1:174933773-174933853 1.0000 80 chr1:43609290-43609370 1.0000 80 chr19:41104205-41104285 1.0000 80 chr10:99078862-99078942 1.0000 80 chr9:130538748-130538828 1.0000 80 chr19:49649556-49649636 1.0000 80 chr1:46519592-46519672 1.0000 80 chr8:124553498-124553578 1.0000 80 chr5:89854408-89854488 1.0000 80 chr4:174256334-174256414 1.0000 80 chr12:25104841-25104921 1.0000 80 chr19:49653060-49653140 1.0000 80 chr2:217277408-217277488 1.0000 80 chr11:66336087-66336167 1.0000 80 chr1:1624434-1624514 1.0000 80 chr5:42812095-42812175 1.0000 80 chr7:100084917-100084997 1.0000 80 chr17:7387391-7387471 1.0000 80 chr14:39901484-39901564 1.0000 80 chr10:112624559-11262463 1.0000 80 chr4:90032278-90032358 1.0000 80 chr13:76112087-76112167 1.0000 80 chr2:220589530-220589610 1.0000 80 chr15:65476788-65476868 1.0000 80 chr14:57046356-57046436 1.0000 80 chr22:39052496-39052576 1.0000 80 chr8:107669911-107669991 1.0000 80 chr15:44975605-44975685 1.0000 80 chr22:36635615-36635695 1.0000 80 chr13:76123730-76123810 1.0000 80 chr11:72525234-72525314 1.0000 80 chr7:21985632-21985712 1.0000 80 chrX:47077913-47077993 1.0000 80 chr7:2595226-2595306 1.0000 80 chr12:54763029-54763109 1.0000 80 chr7:22748019-22748099 1.0000 80 chr13:115078850-11507893 1.0000 80 chr17:53653975-53654055 1.0000 80 chr16:85222595-85222675 1.0000 80 chrX:53024931-53025011 1.0000 80 chr19:14153942-14154022 1.0000 80 chr20:48669267-48669347 1.0000 80 chr16:70099988-70100068 1.0000 80 chr7:105226394-105226474 1.0000 80 chr17:7589674-7589754 1.0000 80 chr5:173345050-173345130 1.0000 80 chr11:125933049-12593312 1.0000 80 chr7:38262269-38262349 1.0000 80 chrX:48596001-48596081 1.0000 80 chr15:48624172-48624252 1.0000 80 chr8:86951782-86951862 1.0000 80 chr9:15511084-15511164 1.0000 80 chr4:13486111-13486191 1.0000 80 chr14:75348500-75348580 1.0000 80 chr14:39736408-39736488 1.0000 80 chr3:50359013-50359093 1.0000 80 chr18:19315648-19315728 1.0000 80 chr20:8978537-8978617 1.0000 80 chr2:74007263-74007343 1.0000 80 chr14:104410129-10441020 1.0000 80 chr7:150925752-150925832 1.0000 80 chrX:47420768-47420848 1.0000 80 chr1:1677817-1677897 1.0000 80 chr19:47200971-47201051 1.0000 80 chr21:43870277-43870357 1.0000 80 chr2:87303633-87303713 1.0000 80 chrX:118827246-118827326 1.0000 80 chr3:160473049-160473129 1.0000 80 chr11:129872520-12987260 1.0000 80 chr10:99094567-99094647 1.0000 80 chr5:133862609-133862689 1.0000 80 chr20:524584-524664 1.0000 80 chr1:205718065-205718145 1.0000 80 chrX:19002635-19002715 1.0000 80 chr3:13690047-13690127 1.0000 80 chr20:814338-814418 1.0000 80 chr12:106696364-10669644 1.0000 80 chr1:154909551-154909631 1.0000 80 chr2:113299596-113299676 1.0000 80 chr1:167729349-167729429 1.0000 80 chr10:123822896-12382297 1.0000 80 chr7:150925548-150925628 1.0000 80 chrX:47050099-47050179 1.0000 80 chr2:120301828-120301908 1.0000 80 chr12:125391358-12539143 1.0000 80 chr4:42659360-42659440 1.0000 80 chrX:48858764-48858844 1.0000 80 chr10:73079582-73079662 1.0000 80 chr11:85913849-85913929 1.0000 80 chr7:2394036-2394116 1.0000 80 chr19:49653705-49653785 1.0000 80 chr20:32581481-32581561 1.0000 80 chr5:64920016-64920096 1.0000 80 chr1:110361109-110361189 1.0000 80 chr1:84464905-84464985 1.0000 80 chr20:53710946-53711026 1.0000 80 chr11:63606179-63606259 1.0000 80 chr22:38199695-38199775 1.0000 80 chr18:3037573-3037653 1.0000 80 chr7:99724839-99724919 1.0000 80 chr14:45603532-45603612 1.0000 80 chr19:33161015-33161095 1.0000 80 chr15:65117993-65118073 1.0000 80 chr16:29973137-29973217 1.0000 80 chrX:119077738-119077818 1.0000 80 chr16:15068679-15068759 1.0000 80 chr1:6661286-6661366 1.0000 80 chr12:33674078-33674158 1.0000 80 chr17:77809984-77810064 1.0000 80 chr3:152944785-152944865 1.0000 80 chr10:127511937-12751201 1.0000 80 chr20:2083064-2083144 1.0000 80 chr1:19229152-19229232 1.0000 80 chr17:62103161-62103241 1.0000 80 chr7:102678687-102678767 1.0000 80 chr7:127087563-127087643 1.0000 80 chr5:148737228-148737308 1.0000 80 chr11:58538535-58538615 1.0000 80 chr10:99400301-99400381 1.0000 80 chr17:17140609-17140689 1.0000 80 chr19:6737368-6737448 1.0000 80 chr14:92588125-92588205 1.0000 80 chr8:74152844-74152924 1.0000 80 chr10:104677812-10467789 1.0000 80 chr3:66271364-66271444 1.0000 80 chr19:50179813-50179893 1.0000 80 chr6:110501012-110501092 1.0000 80 chr7:66460649-66460729 1.0000 80 chr21:19192040-19192120 1.0000 80 chr17:65990729-65990809 1.0000 80 chr9:34328753-34328833 1.0000 80 chr1:169452935-169453015 1.0000 80 chr1:155658676-155658756 1.0000 80 chr17:66453976-66454056 1.0000 80 chr7:100887704-100887784 1.0000 80 chrX:48754492-48754572 1.0000 80 chr1:6052138-6052218 1.0000 80 chr7:1094828-1094908 1.0000 80 chr5:180671268-180671348 1.0000 80 chr7:43909106-43909186 1.0000 80 chr18:11987829-11987909 1.0000 80 chr7:99284050-99284130 1.0000 80 chr20:42219368-42219448 1.0000 80 chr3:36949643-36949723 1.0000 80 chr11:109811672-10981175 1.0000 80 chrX:48755366-48755446 1.0000 80 chr8:26240437-26240517 1.0000 80 chr10:73079380-73079460 1.0000 80 chr3:185827026-185827106 1.0000 80 chr15:72766016-72766096 1.0000 80 chr4:73712296-73712376 1.0000 80 chr11:45921465-45921545 1.0000 80 chr18:21067931-21068011 1.0000 80 chr19:36869922-36870002 1.0000 80 chr6:160114478-160114558 1.0000 80 chr1:8586061-8586141 1.0000 80 chr19:55964535-55964615 1.0000 80 chr1:159787477-159787557 1.0000 80 chr11:62475033-62475113 1.0000 80 chr10:22802908-22802988 1.0000 80 chr5:139641063-139641143 1.0000 80 chr11:65260364-65260444 1.0000 80 chr6:33167856-33167936 1.0000 80 chr19:45996578-45996658 1.0000 80 chr7:87849498-87849578 1.0000 80 chr4:141334911-141334991 1.0000 80 chr2:44314506-44314586 1.0000 80 chr19:55678289-55678369 1.0000 80 chr12:48803867-48803947 1.0000 80 chr2:240240174-240240254 1.0000 80 chr11:47290722-47290802 1.0000 80 chr19:30335313-30335393 1.0000 80 chrX:48937485-48937565 1.0000 80 chr19:48281750-48281830 1.0000 80 chr2:201676397-201676477 1.0000 80 chr21:44394188-44394268 1.0000 80 chr3:129813196-129813276 1.0000 80 chr6:37140132-37140212 1.0000 80 chr19:42806779-42806859 1.0000 80 chr22:38859488-38859568 1.0000 80 chr16:4674510-4674590 1.0000 80 chr1:182284460-182284540 1.0000 80 chr4:104119624-104119704 1.0000 80 chr12:56520113-56520193 1.0000 80 chr18:10578192-10578272 1.0000 80 chr1:245508949-245509029 1.0000 80 chr17:44269113-44269193 1.0000 80 chr7:156931104-156931184 1.0000 80 chr7:134832698-134832778 1.0000 80 chr1:27853736-27853816 1.0000 80 chr22:47487211-47487291 1.0000 80 chr1:147013218-147013298 1.0000 80 chr11:57103072-57103152 1.0000 80 chr4:77870783-77870863 1.0000 80 chr4:69227075-69227155 1.0000 80 chr14:35008836-35008916 1.0000 80 chr7:123387811-123387891 1.0000 80 chr5:137673644-137673724 1.0000 80 chr12:120755561-12075564 1.0000 80 chr22:21822539-21822619 1.0000 80 chr8:129356300-129356380 1.0000 80 chr16:2255287-2255367 1.0000 80 chr4:103746821-103746901 1.0000 80 chr17:36956236-36956316 1.0000 80 chrX:49022872-49022952 1.0000 80 chr17:34136218-34136298 1.0000 80 ******************************************************************************** ******************************************************************************** COMMAND LINE SUMMARY ******************************************************************************** This information can also be useful in the event you wish to report a problem with the MEME software. command: meme -oc ../result/final_prediction/K562/inference_raw/MEME/RankLinear0.6_40_FOXK2/ -dna -nmotifs 5 -w 8 -maxsize 250000 -nostatus ../result/final_prediction/K562/fasta/RankLinear0.6_40/FOXK2.fasta model: mod= zoops nmotifs= 5 evt= inf objective function: em= E-value of product of p-values starts= E-value of product of p-values strands: + width: minw= 8 maxw= 8 nsites: minsites= 2 maxsites= 250 wnsites= 0.8 theta: spmap= uni spfuzz= 0.5 em: prior= dirichlet b= 0.01 maxiter= 50 distance= 1e-05 trim: wg= 11 ws= 1 endgaps= yes data: n= 20000 N= 250 sample: seed= 0 hsfrac= 0 searchsize= 20000 norand= no csites= 1000 Letter frequencies in dataset: A 0.237 C 0.272 G 0.273 T 0.217 Background letter frequencies (from file dataset with add-one prior applied): A 0.237 C 0.272 G 0.273 T 0.217 Background model order: 0 ******************************************************************************** ******************************************************************************** MOTIF TGTWWACA MEME-1 width = 8 sites = 82 llr = 702 E-value = 8.8e-066 ******************************************************************************** -------------------------------------------------------------------------------- Motif TGTWWACA MEME-1 Description -------------------------------------------------------------------------------- Simplified A 1::55a:9 pos.-specific C ::::::a1 probability G 1a:::::: matrix T 8:a55::1 bits 2.2 2.0 * * 1.8 ** ** 1.5 ** ** Relative 1.3 ** *** Entropy 1.1 ******** (12.4 bits) 0.9 ******** 0.7 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel TGTAAACA consensus TT sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGTWWACA MEME-1 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr4:69227075-69227155 48 2.11e-05 GCTTGTAGAA TGTAAACA TGAGGCCCTG chr1:27853736-27853816 35 2.11e-05 CTCGGTTACA TGTAAACA CCAGCTGTGT chr7:156931104-156931184 30 2.11e-05 ACAGGTGGGA TGTAAACA GACGGGCTGG chr6:37140132-37140212 49 2.11e-05 ACCCAAAGTT TGTAAACA GGAATCACGT chr19:45996578-45996658 11 2.11e-05 GGAACCGTCT TGTAAACA GCCAAAAGCA chr4:73712296-73712376 50 2.11e-05 aggctcacag tgtaaaca aagcaatgag chr11:109811672-10981175 11 2.11e-05 tgatagagca tgtaaaca agtaactgta chr7:1094828-1094908 15 2.11e-05 GGAACCCGGC TGTAAACA GCAGGAGGGA chr7:102678687-102678767 50 2.11e-05 tagctcacag tgtaaaca aagaggccag chr3:152944785-152944865 52 2.11e-05 aagccggcag tgtaaaca agagcagggt chr19:33161015-33161095 54 2.11e-05 GCAAGAACTG TGTAAACA CACCACGCCC chr2:74007263-74007343 35 2.11e-05 ACTCCTGATC TGTAAACA GGACTTTGGT chr18:19315648-19315728 55 2.11e-05 actctcacag tgtaaaca aagctgccgg chr16:85222595-85222675 12 2.11e-05 actcccagaa tgtaaaca accattgTTA chr15:44975605-44975685 49 2.11e-05 cacctcacag tgtaaaca aagccaccag chr4:90032278-90032358 13 2.11e-05 GGCTGCTGTT TGTAAACA CGCCCCACGT chr1:174933773-174933853 55 2.11e-05 TCATGCAAAC TGTAAACA GCAATGTGGA chr9:140444849-140444929 29 2.11e-05 TCCTTCCCTC TGTAAACA GCCCTCACGT chr8:95907968-95908048 52 2.11e-05 GGCTGCAGAA TGTAAACA CCACTCAGCC chr10:27099511-27099591 45 2.11e-05 cgtaacaata tgtaaaca aaggaacaca chr17:62923807-62923887 50 2.11e-05 CTGTAATGAT TGTAAACA GGCACAAGAG chr1:25758761-25758841 64 2.11e-05 AGCTGACTGA TGTAAACA CTGGGGATT chr14:35008836-35008916 47 4.05e-05 GCAGCGTCTC TGTTTACA CTGCAAGTCC chr7:134832698-134832778 20 4.05e-05 AATAAAAAGT TGTTTACA TACCTCATTT chr1:245508949-245509029 61 4.05e-05 gagatctggt tgtttaca agtgtgtggc chrX:48937485-48937565 57 4.05e-05 CCGGCTCGGG TGTTTACA TCAGGCCCTA chr12:48803867-48803947 24 4.05e-05 ctggcctctt tgtttaca ctgtgagcta chr6:33167856-33167936 48 4.05e-05 AGGGGACGCG TGTTTACA AACAAGGGGG chr10:22802908-22802988 25 4.05e-05 cctgcagctt tgtttaca ctgtgagcat chr15:72766016-72766096 21 4.05e-05 AAATCATCGC TGTTTACA TTGTTTAGGG chr10:73079380-73079460 37 4.05e-05 AGGCTGGGGC TGTTTACA CCGCAAAGCC chr17:65990729-65990809 71 4.05e-05 TTCCCATCCA TGTTTACA CT chr17:62103161-62103241 33 4.05e-05 GGAATGGAGT TGTTTACA AAACCAAGCC chr17:77809984-77810064 60 4.05e-05 GCTGCGCCCT TGTTTACA CAGCGGCAAA chr1:6661286-6661366 28 4.05e-05 CATGTGACCA TGTTTACA GGCTCCGGGG chr18:3037573-3037653 23 4.05e-05 TTCTCCTTCC TGTTTACA TTTTCACTTC chr20:53710946-53711026 22 4.05e-05 agaggtagga tgtttaca tccagagtga chr5:64920016-64920096 64 4.05e-05 GCTCCGAGCT TGTTTACA ACCAGGGTA chr14:104410129-10441020 23 4.05e-05 GAGTAGACGT TGTTTACA TCAGACTTGC chr7:22748019-22748099 24 4.05e-05 gccctgctct tgtttaca ctgccggttt chr2:220589530-220589610 62 4.05e-05 GGTCAGACCT TGTTTACA TGGACACTTG chr10:112624559-11262463 57 4.05e-05 CTGGAGCTGT TGTTTACA AATGCCAGTC chr11:66336087-66336167 23 4.05e-05 CGCGTTCTCT TGTTTACA GGAGGCACGT chr1:46519592-46519672 44 4.05e-05 CTCCTTGCCT TGTTTACA AAGCTCTTCA chr1:15946938-15947018 62 4.05e-05 CTCCTCCTCT TGTTTACA TTCTCCATTC chr6:90650296-90650376 21 4.05e-05 GCTTCATTCT TGTTTACA TTCACGTCTG chr12:46979763-46979843 25 4.05e-05 caggcctctt tgtttaca ttgtgagcta chr8:129356300-129356380 56 6.71e-05 ggcttgctta ggtaaaca aagcagcctg chr4:141334911-141334991 54 6.71e-05 ggcttgatta ggtaaaca aggcagcctg chr7:99284050-99284130 62 6.71e-05 gacttgataa ggtaaaca aagcagctgg chr12:33674078-33674158 50 6.71e-05 ggcttgagta ggtaaaca aagcagctgg chr7:38262269-38262349 54 6.71e-05 GAGTCAGGAA GGTAAACA AAAACAAAAC chr4:174256334-174256414 50 6.71e-05 AATACTGGGA GGTAAACA AGGGCACCCT chrX:109473158-109473238 54 6.71e-05 ggcttgagta ggtaaaca aagcagccag chr15:50296034-50296114 11 6.71e-05 CTCACACCAT GGTAAACA AGGGGTGGAG chr11:9952576-9952656 53 6.71e-05 agcttgcgta ggtaaaca aagaaaccag chr19:55185653-55185733 32 6.71e-05 gctcttagct ggtaaaca gccCGTAAAG chr7:100887704-100887784 10 1.14e-04 CGGCCGAAC AGTAAACA CGCTGTCAGA chr9:34328753-34328833 12 1.14e-04 GCTTCCCGGA AGTAAACA ACCCAAGGGC chr10:99400301-99400381 54 1.14e-04 TTCGTAGCCA AGTAAACA GGGCAGGTTA chr7:127087563-127087643 16 1.14e-04 agcttctgct agtaaaca aggatcaaat chr12:125391358-12539143 34 1.14e-04 CTTACTGATA AGTAAACA AGCCTCTGGA chr7:150925548-150925628 52 1.14e-04 acatgtgaaa agtaaaca agccgggtgt chr10:123822896-12382297 19 1.14e-04 TTTGGCAGGA AGTAAACA CAGAAAGGAG chr22:36635615-36635695 51 1.14e-04 GACCAAGCAC AGTAAACA CGCTGCTCCC chr12:56520113-56520193 64 1.97e-04 GGACCCACCC TGTTTACT TGTGTTGGT chr1:182284460-182284540 61 1.97e-04 CCTTCTGCCT TGTTTACT TAATTTACTG chr17:53653975-53654055 23 1.97e-04 tatttcttct tgtttact tcctcttttt chr1:118277851-118277931 21 1.97e-04 CATTTTGTGC TGTTTACT TTATAAAAGT chr7:99104180-99104260 70 1.97e-04 ATATCCAGTG TGTTAACC TGT chr12:120763373-12076345 34 1.97e-04 GTTGCTGTGA TGTTTACT GTTGCTACAT chr18:10578192-10578272 12 2.19e-04 ctggctgctt tgtttacc taagcaagcc chr19:30335313-30335393 57 2.19e-04 ACGTGCGCCG TGTTTACC CACGTGATGC chr2:44314506-44314586 43 2.19e-04 GACGTCACCT TGTTTACC CGGCTCCGGG chr8:74152844-74152924 23 2.19e-04 ctggctgctt tgtttacc tactcgagcc chr5:133862609-133862689 21 2.19e-04 GCGTGGCCCT TGTTTACC TTCTCCCAAC chr17:34136218-34136298 12 2.36e-04 GAAATAGGAT TGTAAATA AGACGGAGCA chr5:42812095-42812175 24 2.71e-04 CTGAGCTGAT TGTTATCA ACTTAAAAGA chr1:167191643-167191723 30 2.71e-04 CCCAACGCCG TGTTTATA TTTTACATTC chr17:66453976-66454056 22 2.89e-04 CACGTGGCGG TGTTTTCA TTGCCGGAGC chr5:139641063-139641143 56 3.12e-04 CGGGAGACAG TGAAAACA AGCAAGAGCT chr3:72201905-72201985 63 3.12e-04 TCCAGGAGGA TGAAAACA TCCAGTGACT -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGTWWACA MEME-1 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr4:69227075-69227155 2.1e-05 47_[+1]_25 chr1:27853736-27853816 2.1e-05 34_[+1]_38 chr7:156931104-156931184 2.1e-05 29_[+1]_43 chr6:37140132-37140212 2.1e-05 48_[+1]_24 chr19:45996578-45996658 2.1e-05 10_[+1]_62 chr4:73712296-73712376 2.1e-05 49_[+1]_23 chr11:109811672-10981175 2.1e-05 10_[+1]_62 chr7:1094828-1094908 2.1e-05 14_[+1]_58 chr7:102678687-102678767 2.1e-05 49_[+1]_23 chr3:152944785-152944865 2.1e-05 51_[+1]_21 chr19:33161015-33161095 2.1e-05 53_[+1]_19 chr2:74007263-74007343 2.1e-05 34_[+1]_38 chr18:19315648-19315728 2.1e-05 54_[+1]_18 chr16:85222595-85222675 2.1e-05 11_[+1]_61 chr15:44975605-44975685 2.1e-05 48_[+1]_24 chr4:90032278-90032358 2.1e-05 12_[+1]_60 chr1:174933773-174933853 2.1e-05 54_[+1]_18 chr9:140444849-140444929 2.1e-05 28_[+1]_44 chr8:95907968-95908048 2.1e-05 51_[+1]_21 chr10:27099511-27099591 2.1e-05 44_[+1]_28 chr17:62923807-62923887 2.1e-05 49_[+1]_23 chr1:25758761-25758841 2.1e-05 63_[+1]_9 chr14:35008836-35008916 4e-05 46_[+1]_26 chr7:134832698-134832778 4e-05 19_[+1]_53 chr1:245508949-245509029 4e-05 60_[+1]_12 chrX:48937485-48937565 4e-05 56_[+1]_16 chr12:48803867-48803947 4e-05 23_[+1]_49 chr6:33167856-33167936 4e-05 47_[+1]_25 chr10:22802908-22802988 4e-05 24_[+1]_48 chr15:72766016-72766096 4e-05 20_[+1]_52 chr10:73079380-73079460 4e-05 36_[+1]_36 chr17:65990729-65990809 4e-05 70_[+1]_2 chr17:62103161-62103241 4e-05 32_[+1]_40 chr17:77809984-77810064 4e-05 59_[+1]_13 chr1:6661286-6661366 4e-05 27_[+1]_45 chr18:3037573-3037653 4e-05 22_[+1]_50 chr20:53710946-53711026 4e-05 21_[+1]_51 chr5:64920016-64920096 4e-05 63_[+1]_9 chr14:104410129-10441020 4e-05 22_[+1]_50 chr7:22748019-22748099 4e-05 23_[+1]_49 chr2:220589530-220589610 4e-05 61_[+1]_11 chr10:112624559-11262463 4e-05 56_[+1]_16 chr11:66336087-66336167 4e-05 22_[+1]_50 chr1:46519592-46519672 4e-05 43_[+1]_29 chr1:15946938-15947018 4e-05 61_[+1]_11 chr6:90650296-90650376 4e-05 20_[+1]_52 chr12:46979763-46979843 4e-05 24_[+1]_48 chr8:129356300-129356380 6.7e-05 55_[+1]_17 chr4:141334911-141334991 6.7e-05 53_[+1]_19 chr7:99284050-99284130 6.7e-05 61_[+1]_11 chr12:33674078-33674158 6.7e-05 49_[+1]_23 chr7:38262269-38262349 6.7e-05 53_[+1]_19 chr4:174256334-174256414 6.7e-05 49_[+1]_23 chrX:109473158-109473238 6.7e-05 53_[+1]_19 chr15:50296034-50296114 6.7e-05 10_[+1]_62 chr11:9952576-9952656 6.7e-05 52_[+1]_20 chr19:55185653-55185733 6.7e-05 31_[+1]_41 chr7:100887704-100887784 0.00011 9_[+1]_63 chr9:34328753-34328833 0.00011 11_[+1]_61 chr10:99400301-99400381 0.00011 53_[+1]_19 chr7:127087563-127087643 0.00011 15_[+1]_57 chr12:125391358-12539143 0.00011 33_[+1]_39 chr7:150925548-150925628 0.00011 51_[+1]_21 chr10:123822896-12382297 0.00011 18_[+1]_54 chr22:36635615-36635695 0.00011 50_[+1]_22 chr12:56520113-56520193 0.0002 63_[+1]_9 chr1:182284460-182284540 0.0002 60_[+1]_12 chr17:53653975-53654055 0.0002 22_[+1]_50 chr1:118277851-118277931 0.0002 20_[+1]_52 chr7:99104180-99104260 0.0002 69_[+1]_3 chr12:120763373-12076345 0.0002 33_[+1]_39 chr18:10578192-10578272 0.00022 11_[+1]_61 chr19:30335313-30335393 0.00022 56_[+1]_16 chr2:44314506-44314586 0.00022 42_[+1]_30 chr8:74152844-74152924 0.00022 22_[+1]_50 chr5:133862609-133862689 0.00022 20_[+1]_52 chr17:34136218-34136298 0.00024 11_[+1]_61 chr5:42812095-42812175 0.00027 23_[+1]_49 chr1:167191643-167191723 0.00027 29_[+1]_43 chr17:66453976-66454056 0.00029 21_[+1]_51 chr5:139641063-139641143 0.00031 55_[+1]_17 chr3:72201905-72201985 0.00031 62_[+1]_10 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGTWWACA MEME-1 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF TGTWWACA width=8 seqs=82 chr4:69227075-69227155 ( 48) TGTAAACA 1 chr1:27853736-27853816 ( 35) TGTAAACA 1 chr7:156931104-156931184 ( 30) TGTAAACA 1 chr6:37140132-37140212 ( 49) TGTAAACA 1 chr19:45996578-45996658 ( 11) TGTAAACA 1 chr4:73712296-73712376 ( 50) TGTAAACA 1 chr11:109811672-10981175 ( 11) TGTAAACA 1 chr7:1094828-1094908 ( 15) TGTAAACA 1 chr7:102678687-102678767 ( 50) TGTAAACA 1 chr3:152944785-152944865 ( 52) TGTAAACA 1 chr19:33161015-33161095 ( 54) TGTAAACA 1 chr2:74007263-74007343 ( 35) TGTAAACA 1 chr18:19315648-19315728 ( 55) TGTAAACA 1 chr16:85222595-85222675 ( 12) TGTAAACA 1 chr15:44975605-44975685 ( 49) TGTAAACA 1 chr4:90032278-90032358 ( 13) TGTAAACA 1 chr1:174933773-174933853 ( 55) TGTAAACA 1 chr9:140444849-140444929 ( 29) TGTAAACA 1 chr8:95907968-95908048 ( 52) TGTAAACA 1 chr10:27099511-27099591 ( 45) TGTAAACA 1 chr17:62923807-62923887 ( 50) TGTAAACA 1 chr1:25758761-25758841 ( 64) TGTAAACA 1 chr14:35008836-35008916 ( 47) TGTTTACA 1 chr7:134832698-134832778 ( 20) TGTTTACA 1 chr1:245508949-245509029 ( 61) TGTTTACA 1 chrX:48937485-48937565 ( 57) TGTTTACA 1 chr12:48803867-48803947 ( 24) TGTTTACA 1 chr6:33167856-33167936 ( 48) TGTTTACA 1 chr10:22802908-22802988 ( 25) TGTTTACA 1 chr15:72766016-72766096 ( 21) TGTTTACA 1 chr10:73079380-73079460 ( 37) TGTTTACA 1 chr17:65990729-65990809 ( 71) TGTTTACA 1 chr17:62103161-62103241 ( 33) TGTTTACA 1 chr17:77809984-77810064 ( 60) TGTTTACA 1 chr1:6661286-6661366 ( 28) TGTTTACA 1 chr18:3037573-3037653 ( 23) TGTTTACA 1 chr20:53710946-53711026 ( 22) TGTTTACA 1 chr5:64920016-64920096 ( 64) TGTTTACA 1 chr14:104410129-10441020 ( 23) TGTTTACA 1 chr7:22748019-22748099 ( 24) TGTTTACA 1 chr2:220589530-220589610 ( 62) TGTTTACA 1 chr10:112624559-11262463 ( 57) TGTTTACA 1 chr11:66336087-66336167 ( 23) TGTTTACA 1 chr1:46519592-46519672 ( 44) TGTTTACA 1 chr1:15946938-15947018 ( 62) TGTTTACA 1 chr6:90650296-90650376 ( 21) TGTTTACA 1 chr12:46979763-46979843 ( 25) TGTTTACA 1 chr8:129356300-129356380 ( 56) GGTAAACA 1 chr4:141334911-141334991 ( 54) GGTAAACA 1 chr7:99284050-99284130 ( 62) GGTAAACA 1 chr12:33674078-33674158 ( 50) GGTAAACA 1 chr7:38262269-38262349 ( 54) GGTAAACA 1 chr4:174256334-174256414 ( 50) GGTAAACA 1 chrX:109473158-109473238 ( 54) GGTAAACA 1 chr15:50296034-50296114 ( 11) GGTAAACA 1 chr11:9952576-9952656 ( 53) GGTAAACA 1 chr19:55185653-55185733 ( 32) GGTAAACA 1 chr7:100887704-100887784 ( 10) AGTAAACA 1 chr9:34328753-34328833 ( 12) AGTAAACA 1 chr10:99400301-99400381 ( 54) AGTAAACA 1 chr7:127087563-127087643 ( 16) AGTAAACA 1 chr12:125391358-12539143 ( 34) AGTAAACA 1 chr7:150925548-150925628 ( 52) AGTAAACA 1 chr10:123822896-12382297 ( 19) AGTAAACA 1 chr22:36635615-36635695 ( 51) AGTAAACA 1 chr12:56520113-56520193 ( 64) TGTTTACT 1 chr1:182284460-182284540 ( 61) TGTTTACT 1 chr17:53653975-53654055 ( 23) TGTTTACT 1 chr1:118277851-118277931 ( 21) TGTTTACT 1 chr7:99104180-99104260 ( 70) TGTTAACC 1 chr12:120763373-12076345 ( 34) TGTTTACT 1 chr18:10578192-10578272 ( 12) TGTTTACC 1 chr19:30335313-30335393 ( 57) TGTTTACC 1 chr2:44314506-44314586 ( 43) TGTTTACC 1 chr8:74152844-74152924 ( 23) TGTTTACC 1 chr5:133862609-133862689 ( 21) TGTTTACC 1 chr17:34136218-34136298 ( 12) TGTAAATA 1 chr5:42812095-42812175 ( 24) TGTTATCA 1 chr1:167191643-167191723 ( 30) TGTTTATA 1 chr17:66453976-66454056 ( 22) TGTTTTCA 1 chr5:139641063-139641143 ( 56) TGAAAACA 1 chr3:72201905-72201985 ( 63) TGAAAACA 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGTWWACA MEME-1 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 8.75997 E= 8.8e-066 -128 -1300 -116 184 -1300 -1300 187 -1300 -328 -1300 -1300 217 114 -1300 -1300 113 121 -1300 -1300 105 204 -1300 -1300 -315 -1300 184 -1300 -315 187 -189 -1300 -183 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGTWWACA MEME-1 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 82 E= 8.8e-066 0.097561 0.000000 0.121951 0.780488 0.000000 0.000000 1.000000 0.000000 0.024390 0.000000 0.000000 0.975610 0.524390 0.000000 0.000000 0.475610 0.548780 0.000000 0.000000 0.451220 0.975610 0.000000 0.000000 0.024390 0.000000 0.975610 0.000000 0.024390 0.865854 0.073171 0.000000 0.060976 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGTWWACA MEME-1 regular expression -------------------------------------------------------------------------------- TGT[AT][AT]ACA -------------------------------------------------------------------------------- Time 4.77 secs. ******************************************************************************** ******************************************************************************** MOTIF GGGGAGGG MEME-2 width = 8 sites = 34 llr = 303 E-value = 4.1e-009 ******************************************************************************** -------------------------------------------------------------------------------- Motif GGGGAGGG MEME-2 Description -------------------------------------------------------------------------------- Simplified A ::2:8::: pos.-specific C :::1:::: probability G 8a89:aaa matrix T 2:::2::: bits 2.2 2.0 1.8 * *** 1.5 * * *** Relative 1.3 ** ***** Entropy 1.1 ******** (12.8 bits) 0.9 ******** 0.7 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel GGGGAGGG consensus A T sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GGGGAGGG MEME-2 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr8:129356300-129356380 21 2.68e-05 agcgaggctg ggggaggg gcgcccgcca chr19:42806779-42806859 55 2.68e-05 CACCGGTCAC GGGGAGGG GCGAACTACC chr4:141334911-141334991 19 2.68e-05 agcgaggctg ggggaggg gcgcccgcca chr6:33167856-33167936 10 2.68e-05 cgccccggg ggggAGGG TGCTAAGGCC chr11:62475033-62475113 5 2.68e-05 AATG GGGGAGGG GCAGGCAGTG chr7:99284050-99284130 27 2.68e-05 agtgaggctg ggggaggg gtgcctgcca chr19:6737368-6737448 9 2.68e-05 CGGGGACG GGGGAGGG CGGACGAGAC chr11:58538535-58538615 44 2.68e-05 ggcatgatgt ggggaggg acagatctct chr7:102678687-102678767 7 2.68e-05 tggcgg ggggaggg gcatctgcca chr17:77809984-77810064 42 2.68e-05 CACTAAACAG GGGGAGGG GCTGCGCCCT chr12:33674078-33674158 15 2.68e-05 agcctggctg ggggaggg gcgtccacca chr18:19315648-19315728 1 2.68e-05 . ggggaggg gcatccgcca chr1:1624434-1624514 6 2.68e-05 CACAC GGGGAGGG ACACGGCGCG chr19:49649556-49649636 59 2.68e-05 GCTTGGCGGT GGGGAGGG TAGAGGGGAT chrX:109473158-109473238 19 2.68e-05 agcctggctg ggggaggg gtatccgcca chr11:9952576-9952656 18 2.68e-05 agcctggctg ggggaggg gcatctgcca chr4:104119624-104119704 56 7.46e-05 CTGCTAAACA GGAGAGGG GATTTAAAGG chrX:48755366-48755446 8 7.46e-05 TAACGTT GGGGTGGG TGCACTCTTT chr7:43909106-43909186 30 7.46e-05 AGCGCGCTGA GGGGTGGG GACGACCGCG chr17:66453976-66454056 54 7.46e-05 CAGCTGGGAG GGAGAGGG AAGAAGGAAT chrX:118827246-118827326 28 7.46e-05 AGTAGGGTAT GGAGAGGG GGCGGATTTA chrX:47420768-47420848 48 7.46e-05 GTCGACAGCG GGGGTGGG GTGGGTAACA chr2:217277408-217277488 72 7.46e-05 GGAGATCGTA GGGGTGGG A chr1:174933773-174933853 70 7.46e-05 ACAGCAATGT GGAGAGGG AGG chr7:44078884-44078964 16 7.46e-05 CATGGGTCTA GGGGTGGG GCAAACGTCA chrX:49022872-49022952 66 9.59e-05 CTTCTGGTTC TGGGAGGG GGAGGTA chr11:63606179-63606259 58 9.59e-05 GGCAGGGCTG TGGGAGGG GGCGTGGCCG chr10:123822896-12382297 39 9.59e-05 GAAAGGAGAG TGGGAGGG AGAGGAGGAG chr1:43609290-43609370 45 1.17e-04 TAGGCACCCA GGAGTGGG CAGTCATCCT chr11:47290722-47290802 70 1.55e-04 GCCTTGGCCG TGAGAGGG GGC chr11:129872520-12987260 3 1.55e-04 TT TGGGTGGG ACTAAGCAAA chr19:41104205-41104285 37 1.55e-04 CCCACCCACC TGAGAGGG GCCCACGCGC chr7:99724839-99724919 8 1.82e-04 CCATTTT GGGCAGGG GTTGAGGGTG chr7:100084917-100084997 64 1.82e-04 AACCATTCAA GGGCAGGG GACACTCCC -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GGGGAGGG MEME-2 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr8:129356300-129356380 2.7e-05 20_[+2]_52 chr19:42806779-42806859 2.7e-05 54_[+2]_18 chr4:141334911-141334991 2.7e-05 18_[+2]_54 chr6:33167856-33167936 2.7e-05 9_[+2]_63 chr11:62475033-62475113 2.7e-05 4_[+2]_68 chr7:99284050-99284130 2.7e-05 26_[+2]_46 chr19:6737368-6737448 2.7e-05 8_[+2]_64 chr11:58538535-58538615 2.7e-05 43_[+2]_29 chr7:102678687-102678767 2.7e-05 6_[+2]_66 chr17:77809984-77810064 2.7e-05 41_[+2]_31 chr12:33674078-33674158 2.7e-05 14_[+2]_58 chr18:19315648-19315728 2.7e-05 [+2]_72 chr1:1624434-1624514 2.7e-05 5_[+2]_67 chr19:49649556-49649636 2.7e-05 58_[+2]_14 chrX:109473158-109473238 2.7e-05 18_[+2]_54 chr11:9952576-9952656 2.7e-05 17_[+2]_55 chr4:104119624-104119704 7.5e-05 55_[+2]_17 chrX:48755366-48755446 7.5e-05 7_[+2]_65 chr7:43909106-43909186 7.5e-05 29_[+2]_43 chr17:66453976-66454056 7.5e-05 53_[+2]_19 chrX:118827246-118827326 7.5e-05 27_[+2]_45 chrX:47420768-47420848 7.5e-05 47_[+2]_25 chr2:217277408-217277488 7.5e-05 71_[+2]_1 chr1:174933773-174933853 7.5e-05 69_[+2]_3 chr7:44078884-44078964 7.5e-05 15_[+2]_57 chrX:49022872-49022952 9.6e-05 65_[+2]_7 chr11:63606179-63606259 9.6e-05 57_[+2]_15 chr10:123822896-12382297 9.6e-05 38_[+2]_34 chr1:43609290-43609370 0.00012 44_[+2]_28 chr11:47290722-47290802 0.00016 69_[+2]_3 chr11:129872520-12987260 0.00016 2_[+2]_70 chr19:41104205-41104285 0.00016 36_[+2]_36 chr7:99724839-99724919 0.00018 7_[+2]_65 chr7:100084917-100084997 0.00018 63_[+2]_9 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GGGGAGGG MEME-2 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF GGGGAGGG width=8 seqs=34 chr8:129356300-129356380 ( 21) GGGGAGGG 1 chr19:42806779-42806859 ( 55) GGGGAGGG 1 chr4:141334911-141334991 ( 19) GGGGAGGG 1 chr6:33167856-33167936 ( 10) GGGGAGGG 1 chr11:62475033-62475113 ( 5) GGGGAGGG 1 chr7:99284050-99284130 ( 27) GGGGAGGG 1 chr19:6737368-6737448 ( 9) GGGGAGGG 1 chr11:58538535-58538615 ( 44) GGGGAGGG 1 chr7:102678687-102678767 ( 7) GGGGAGGG 1 chr17:77809984-77810064 ( 42) GGGGAGGG 1 chr12:33674078-33674158 ( 15) GGGGAGGG 1 chr18:19315648-19315728 ( 1) GGGGAGGG 1 chr1:1624434-1624514 ( 6) GGGGAGGG 1 chr19:49649556-49649636 ( 59) GGGGAGGG 1 chrX:109473158-109473238 ( 19) GGGGAGGG 1 chr11:9952576-9952656 ( 18) GGGGAGGG 1 chr4:104119624-104119704 ( 56) GGAGAGGG 1 chrX:48755366-48755446 ( 8) GGGGTGGG 1 chr7:43909106-43909186 ( 30) GGGGTGGG 1 chr17:66453976-66454056 ( 54) GGAGAGGG 1 chrX:118827246-118827326 ( 28) GGAGAGGG 1 chrX:47420768-47420848 ( 48) GGGGTGGG 1 chr2:217277408-217277488 ( 72) GGGGTGGG 1 chr1:174933773-174933853 ( 70) GGAGAGGG 1 chr7:44078884-44078964 ( 16) GGGGTGGG 1 chrX:49022872-49022952 ( 66) TGGGAGGG 1 chr11:63606179-63606259 ( 58) TGGGAGGG 1 chr10:123822896-12382297 ( 39) TGGGAGGG 1 chr1:43609290-43609370 ( 45) GGAGTGGG 1 chr11:47290722-47290802 ( 70) TGAGAGGG 1 chr11:129872520-12987260 ( 3) TGGGTGGG 1 chr19:41104205-41104285 ( 37) TGAGAGGG 1 chr7:99724839-99724919 ( 8) GGGCAGGG 1 chr7:100084917-100084997 ( 64) GGGCAGGG 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GGGGAGGG MEME-2 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 9.86128 E= 4.1e-009 -1173 -1173 159 -30 -1173 -1173 187 -1173 -21 -1173 154 -1173 -1173 -221 178 -1173 174 -1173 -1173 -8 -1173 -1173 187 -1173 -1173 -1173 187 -1173 -1173 -1173 187 -1173 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GGGGAGGG MEME-2 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 34 E= 4.1e-009 0.000000 0.000000 0.823529 0.176471 0.000000 0.000000 1.000000 0.000000 0.205882 0.000000 0.794118 0.000000 0.000000 0.058824 0.941176 0.000000 0.794118 0.000000 0.000000 0.205882 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GGGGAGGG MEME-2 regular expression -------------------------------------------------------------------------------- GG[GA]G[AT]GGG -------------------------------------------------------------------------------- Time 8.42 secs. ******************************************************************************** ******************************************************************************** MOTIF CCCTCCCC MEME-3 width = 8 sites = 33 llr = 275 E-value = 3.6e-001 ******************************************************************************** -------------------------------------------------------------------------------- Motif CCCTCCCC MEME-3 Description -------------------------------------------------------------------------------- Simplified A :::2:::: pos.-specific C 9aa:8aa9 probability G :::21::: matrix T 1::61::1 bits 2.2 2.0 ** ** 1.8 ** ** 1.5 *** ** Relative 1.3 *** *** Entropy 1.1 *** *** (12.0 bits) 0.9 *** **** 0.7 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel CCCTCCCC consensus A sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCCTCCCC MEME-3 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr18:10578192-10578272 47 2.39e-05 tggcgggcgc ccctcccc cagcctcgct chr11:65260364-65260444 25 2.39e-05 TCCTTTATTC CCCTCCCC GAAAGAGGAT chr10:104677812-10467789 18 2.39e-05 TGGCCACGCC CCCTCCCC TCGCACATAC chr8:74152844-74152924 58 2.39e-05 tggcagacgc ccctcccc cagccagact chrX:48596001-48596081 55 2.39e-05 AATACACGAC CCCTCCCC TGTGGTACCT chr9:130538748-130538828 48 2.39e-05 TATGTGAGTT CCCTCCCC CTGCCCCCAG chr12:46979763-46979843 68 2.39e-05 tggtggacac ccctcccc ccatc chr1:1624233-1624313 44 2.39e-05 GCTCAGCGTC CCCTCCCC CGTTGGTTCT chr17:36956236-36956316 5 5.00e-05 CATG CCCACCCC GGGGGAGAGG chr22:38859488-38859568 48 5.00e-05 GAAGGCTGGG CCCACCCC GCACTCGGTT chrX:118827246-118827326 5 5.00e-05 ACCG CCCACCCC TTGAAAGTAG chr1:1677817-1677897 71 5.00e-05 GAACCGTGGC CCCACCCC CC chr14:75348500-75348580 30 5.00e-05 CCGCCGTGCG CCCACCCC CTGCCAGTGG chr19:49653060-49653140 16 5.00e-05 TCCTTTCTCG CCCACCCC TGAGGAATGG chr16:2255287-2255367 73 8.01e-05 GCGGGAACCC CCCGCCCC chr11:57103072-57103152 10 8.01e-05 CGGTTCACC CCCGCCCC ACATAATGGA chrX:48754492-48754572 52 8.01e-05 CCAACCATGC CCCGCCCC TTTTCAATCC chr19:49653705-49653785 9 8.01e-05 GAAGAAAT CCCGCCCC AAACGTCCGC chr19:47200971-47201051 1 8.01e-05 . cccgcccc ggccACTCAC chr16:75682556-75682636 3 8.01e-05 GC CCCGCCCC CTGTTGACAT chr7:123387811-123387891 54 9.91e-05 ACACACATTC CCCTTCCC ACAGCAGAAC chr17:53653975-53654055 51 9.91e-05 tctctgtctg cccttccc aacccaaccc chr17:7589674-7589754 26 1.18e-04 ACACTTCTTT CCCTCCCT GTCTCACGCC chr2:220589530-220589610 1 1.18e-04 . CCCTCCCT TCTCTGAAGC chr16:4511397-4511477 56 1.18e-04 CAGCCTTGGA CCCTCCCT TACTGCTGTG chr19:55964535-55964615 7 1.42e-04 GCAGCA CCCTGCCC CCCCCACAAG chr8:26240437-26240517 29 1.42e-04 AGGGGAGCGC CCCTGCCC CGTCCGGTCG chr4:90032278-90032358 38 1.42e-04 CGTGCGCTCG CCCTGCCC CATTCGCAGC chr17:34136218-34136298 43 1.61e-04 AGGTTCCACT TCCTCCCC GATCGTGATC chr12:48803867-48803947 67 1.61e-04 tggtggatgc tcctcccc ccatca chrX:48755366-48755446 57 1.82e-04 CCTCTGCTCC CCCATCCC AGCGCTTTGG chr15:48624172-48624252 63 1.82e-04 CCAGTAGTTT CCCATCCC AAACCTGCTT chr11:129872520-12987260 30 2.74e-04 AGACGAAACA CCCTCCCA GTCTATGGGG -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCCTCCCC MEME-3 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr18:10578192-10578272 2.4e-05 46_[+3]_26 chr11:65260364-65260444 2.4e-05 24_[+3]_48 chr10:104677812-10467789 2.4e-05 17_[+3]_55 chr8:74152844-74152924 2.4e-05 57_[+3]_15 chrX:48596001-48596081 2.4e-05 54_[+3]_18 chr9:130538748-130538828 2.4e-05 47_[+3]_25 chr12:46979763-46979843 2.4e-05 67_[+3]_5 chr1:1624233-1624313 2.4e-05 43_[+3]_29 chr17:36956236-36956316 5e-05 4_[+3]_68 chr22:38859488-38859568 5e-05 47_[+3]_25 chrX:118827246-118827326 5e-05 4_[+3]_68 chr1:1677817-1677897 5e-05 70_[+3]_2 chr14:75348500-75348580 5e-05 29_[+3]_43 chr19:49653060-49653140 5e-05 15_[+3]_57 chr16:2255287-2255367 8e-05 72_[+3] chr11:57103072-57103152 8e-05 9_[+3]_63 chrX:48754492-48754572 8e-05 51_[+3]_21 chr19:49653705-49653785 8e-05 8_[+3]_64 chr19:47200971-47201051 8e-05 [+3]_72 chr16:75682556-75682636 8e-05 2_[+3]_70 chr7:123387811-123387891 9.9e-05 53_[+3]_19 chr17:53653975-53654055 9.9e-05 50_[+3]_22 chr17:7589674-7589754 0.00012 25_[+3]_47 chr2:220589530-220589610 0.00012 [+3]_72 chr16:4511397-4511477 0.00012 55_[+3]_17 chr19:55964535-55964615 0.00014 6_[+3]_66 chr8:26240437-26240517 0.00014 28_[+3]_44 chr4:90032278-90032358 0.00014 37_[+3]_35 chr17:34136218-34136298 0.00016 42_[+3]_30 chr12:48803867-48803947 0.00016 66_[+3]_6 chrX:48755366-48755446 0.00018 56_[+3]_16 chr15:48624172-48624252 0.00018 62_[+3]_10 chr11:129872520-12987260 0.00027 29_[+3]_43 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCCTCCCC MEME-3 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF CCCTCCCC width=8 seqs=33 chr18:10578192-10578272 ( 47) CCCTCCCC 1 chr11:65260364-65260444 ( 25) CCCTCCCC 1 chr10:104677812-10467789 ( 18) CCCTCCCC 1 chr8:74152844-74152924 ( 58) CCCTCCCC 1 chrX:48596001-48596081 ( 55) CCCTCCCC 1 chr9:130538748-130538828 ( 48) CCCTCCCC 1 chr12:46979763-46979843 ( 68) CCCTCCCC 1 chr1:1624233-1624313 ( 44) CCCTCCCC 1 chr17:36956236-36956316 ( 5) CCCACCCC 1 chr22:38859488-38859568 ( 48) CCCACCCC 1 chrX:118827246-118827326 ( 5) CCCACCCC 1 chr1:1677817-1677897 ( 71) CCCACCCC 1 chr14:75348500-75348580 ( 30) CCCACCCC 1 chr19:49653060-49653140 ( 16) CCCACCCC 1 chr16:2255287-2255367 ( 73) CCCGCCCC 1 chr11:57103072-57103152 ( 10) CCCGCCCC 1 chrX:48754492-48754572 ( 52) CCCGCCCC 1 chr19:49653705-49653785 ( 9) CCCGCCCC 1 chr19:47200971-47201051 ( 1) CCCGCCCC 1 chr16:75682556-75682636 ( 3) CCCGCCCC 1 chr7:123387811-123387891 ( 54) CCCTTCCC 1 chr17:53653975-53654055 ( 51) CCCTTCCC 1 chr17:7589674-7589754 ( 26) CCCTCCCT 1 chr2:220589530-220589610 ( 1) CCCTCCCT 1 chr16:4511397-4511477 ( 56) CCCTCCCT 1 chr19:55964535-55964615 ( 7) CCCTGCCC 1 chr8:26240437-26240517 ( 29) CCCTGCCC 1 chr4:90032278-90032358 ( 38) CCCTGCCC 1 chr17:34136218-34136298 ( 43) TCCTCCCC 1 chr12:48803867-48803947 ( 67) TCCTCCCC 1 chrX:48755366-48755446 ( 57) CCCATCCC 1 chr15:48624172-48624252 ( 63) CCCATCCC 1 chr11:129872520-12987260 ( 30) CCCTCCCA 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCCTCCCC MEME-3 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 9.14407 E= 3.6e-001 -1169 179 -1169 -184 -1169 188 -1169 -1169 -1169 188 -1169 -1169 3 -1169 -59 141 -1169 153 -159 -84 -1169 188 -1169 -1169 -1169 188 -1169 -1169 -297 169 -1169 -126 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCCTCCCC MEME-3 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 33 E= 3.6e-001 0.000000 0.939394 0.000000 0.060606 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.242424 0.000000 0.181818 0.575758 0.000000 0.787879 0.090909 0.121212 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.030303 0.878788 0.000000 0.090909 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCCTCCCC MEME-3 regular expression -------------------------------------------------------------------------------- CCC[TA]CCCC -------------------------------------------------------------------------------- Time 12.01 secs. ******************************************************************************** ******************************************************************************** MOTIF CTGAGGCT MEME-4 width = 8 sites = 12 llr = 121 E-value = 3.1e+002 ******************************************************************************** -------------------------------------------------------------------------------- Motif CTGAGGCT MEME-4 Description -------------------------------------------------------------------------------- Simplified A :::a:2:: pos.-specific C a2::::a: probability G ::a:a8:: matrix T :8:::::a bits 2.2 * 2.0 * * ** 1.8 * *** ** 1.5 ***** ** Relative 1.3 ******** Entropy 1.1 ******** (14.5 bits) 0.9 ******** 0.7 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel CTGAGGCT consensus sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTGAGGCT MEME-4 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr4:73712296-73712376 17 1.68e-05 atcaccattg ctgaggct tgactaggcg chr10:73079380-73079460 24 1.68e-05 GCTGCGGGGC CTGAGGCT GGGGCTGTTT chr7:102678687-102678767 28 1.68e-05 tctgccattg ctgaggct tgagtagctc chr12:33674078-33674158 36 1.68e-05 tccaccattg ctgaggct tgagtaggta chr18:19315648-19315728 22 1.68e-05 tccgccattg ctgaggct tgcgtaggca chr15:44975605-44975685 16 1.68e-05 tttgccatta ctgaggct tgagtaggtg chrX:109473158-109473238 40 1.68e-05 tccgccattg ctgaggct tgagtaggta chr14:52118269-52118349 51 1.68e-05 CCGCGTCCAC CTGAGGCT CGCCTCGCTT chr2:74007263-74007343 20 3.14e-05 CGCTGGCTTA CTGAGACT CCTGATCTGT chr7:2595226-2595306 7 3.14e-05 GGGGAA CTGAGACT GCACCCCTGG chr1:6052138-6052218 63 5.24e-05 CCCCCGAACC CCGAGGCT CTGGCCAACA chr7:99724839-99724919 59 5.24e-05 TGGCAGAGAA CCGAGGCT TAGGGGCAGT -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTGAGGCT MEME-4 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr4:73712296-73712376 1.7e-05 16_[+4]_56 chr10:73079380-73079460 1.7e-05 23_[+4]_49 chr7:102678687-102678767 1.7e-05 27_[+4]_45 chr12:33674078-33674158 1.7e-05 35_[+4]_37 chr18:19315648-19315728 1.7e-05 21_[+4]_51 chr15:44975605-44975685 1.7e-05 15_[+4]_57 chrX:109473158-109473238 1.7e-05 39_[+4]_33 chr14:52118269-52118349 1.7e-05 50_[+4]_22 chr2:74007263-74007343 3.1e-05 19_[+4]_53 chr7:2595226-2595306 3.1e-05 6_[+4]_66 chr1:6052138-6052218 5.2e-05 62_[+4]_10 chr7:99724839-99724919 5.2e-05 58_[+4]_14 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTGAGGCT MEME-4 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF CTGAGGCT width=8 seqs=12 chr4:73712296-73712376 ( 17) CTGAGGCT 1 chr10:73079380-73079460 ( 24) CTGAGGCT 1 chr7:102678687-102678767 ( 28) CTGAGGCT 1 chr12:33674078-33674158 ( 36) CTGAGGCT 1 chr18:19315648-19315728 ( 22) CTGAGGCT 1 chr15:44975605-44975685 ( 16) CTGAGGCT 1 chrX:109473158-109473238 ( 40) CTGAGGCT 1 chr14:52118269-52118349 ( 51) CTGAGGCT 1 chr2:74007263-74007343 ( 20) CTGAGACT 1 chr7:2595226-2595306 ( 7) CTGAGACT 1 chr1:6052138-6052218 ( 63) CCGAGGCT 1 chr7:99724839-99724919 ( 59) CCGAGGCT 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTGAGGCT MEME-4 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 11.0174 E= 3.1e+002 -1023 188 -1023 -1023 -1023 -71 -1023 194 -1023 -1023 187 -1023 207 -1023 -1023 -1023 -1023 -1023 187 -1023 -51 -1023 161 -1023 -1023 188 -1023 -1023 -1023 -1023 -1023 220 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTGAGGCT MEME-4 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 12 E= 3.1e+002 0.000000 1.000000 0.000000 0.000000 0.000000 0.166667 0.000000 0.833333 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.166667 0.000000 0.833333 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTGAGGCT MEME-4 regular expression -------------------------------------------------------------------------------- CTGAGGCT -------------------------------------------------------------------------------- Time 15.58 secs. ******************************************************************************** ******************************************************************************** MOTIF AARAAAAA MEME-5 width = 8 sites = 40 llr = 314 E-value = 8.6e+001 ******************************************************************************** -------------------------------------------------------------------------------- Motif AARAAAAA MEME-5 Description -------------------------------------------------------------------------------- Simplified A aa486a99 pos.-specific C ::::3::: probability G ::52211: matrix T ::2::::1 bits 2.2 2.0 ** 1.8 ** * 1.5 ** *** Relative 1.3 ** * *** Entropy 1.1 ** * *** (11.3 bits) 0.9 ** * *** 0.7 ** * *** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel AAGAAAAA consensus AGC sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AARAAAAA MEME-5 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr4:69227075-69227155 28 2.14e-05 tatctctgga aaaaaaaa aTGCTTGTAG chr1:147013218-147013298 39 2.14e-05 GGGGAGTCAG AAGAAAAA CAGATCAGAC chr2:201676397-201676477 5 2.14e-05 GGGG AAGAAAAA TAAGCTAGTC chr20:2083064-2083144 19 2.14e-05 GGGCCAAGCA AAGAAAAA TATTTCCGCC chr1:154909551-154909631 50 2.14e-05 AAACTTTAGG AAAAAAAA TCTCTGGAGT chr21:43870277-43870357 48 2.14e-05 GTGTGCTTGA AAAAAAAA ACAAGCCTGg chr7:150925752-150925832 19 2.14e-05 aacaaaaaac aaaaaaaa cagaccttga chr8:107669911-107669991 66 2.14e-05 TAGAAGCCAC AAGAAAAA CTTTTCG chr12:25104841-25104921 22 2.14e-05 ccccatgccc aagaaaaa tgaagatgtg chr7:134832698-134832778 10 3.05e-05 ATAATGGAC AATAAAAA GTTGTTTACA chr1:19229152-19229232 31 3.05e-05 AGCTTCGGCT AATAAAAA ATATTTCTAG chr17:44269113-44269193 4 5.51e-05 CCC AAAACAAA CAAAAAAACA chr7:38262269-38262349 62 5.51e-05 AAGGTAAACA AAAACAAA ACATTTTCAT chr19:14153942-14154022 14 5.51e-05 ctccgtctcc aaaacaaa aaacaaacaa chr14:63568921-63569001 62 5.51e-05 TTTTGCACAG AAAACAAA CTCACATATT chr17:36956236-36956316 40 7.98e-05 CAGCAAGGGG AAGAGAAA GTCCAGCCTA chr13:76112087-76112167 40 7.98e-05 ACATTGAGCT AAAAGAAA ATTATTTTAT chr5:42812095-42812175 36 7.98e-05 TTATCAACTT AAAAGAAA GTAGCAAGTG chr18:21067931-21068011 41 1.04e-04 GCTGCTGTAA AAGGAAAA CAAGCATGTC chr3:36949643-36949723 64 1.04e-04 AGTGAGCAAT AAAGAAAA CAGAAACAG chr7:104909616-104909696 11 1.15e-04 AGCAAAATAA AATACAAA CAAGAAATCT chr9:34328753-34328833 31 1.25e-04 CCCAAGGGCG AATAGAAA TGCCCTAAAA chr5:139641063-139641143 5 1.70e-04 AACT AAAAAAAT AGAGATACGG chr10:112201532-11220161 4 1.70e-04 aga aagaaaga aTACCAGTCC chr17:62923807-62923887 20 1.70e-04 AAAGGAGGCT AAGAAAAT GGATGTGTAC chr2:175190702-175190782 71 1.70e-04 GAGGAACCAG AAGAAAGA GA chrX:47880825-47880905 54 1.70e-04 TACTCCTCTC AAGAAAAT AACAGTAGGG chr3:129813196-129813276 47 2.09e-04 CTTCTCTGTG AAGGCAAA GGGCCTCTGA chr9:33375443-33375523 55 2.09e-04 gggaaggttt aaggcaaa ggagtgaatg chr19:55185653-55185733 46 2.09e-04 aacagccCGT AAAGCAAA AAGTAAATAA chr14:92588125-92588205 73 2.56e-04 ATAATTTCTG AATAAAAT chr4:42659360-42659440 65 2.56e-04 TCTTGCTCAG AAAGGAAA GACTGCTC chr7:150925548-150925628 30 2.56e-04 gggagctcat aataaaga aggaacatgt chr2:113299596-113299676 73 2.56e-04 GGAACAGGTG AAGGGAAA chr22:36635615-36635695 4 2.56e-04 CGA AAGGGAAA GTGAAAGTCA chr1:169452935-169453015 19 3.51e-04 AGCACATGAC AAAACAGA TCAGCTTTCA chr3:66271364-66271444 58 3.51e-04 CCGGAAGTTC AAGACAGA CCCGCCTCAA chr4:13486111-13486191 30 3.51e-04 AGTTGGCTAG AAGAAGAA AAGAAGTGTT chr9:15511084-15511164 69 3.51e-04 GACGCAAGCG AAGAAGAA AGGA chrX:119077738-119077818 32 4.85e-04 TGTGTGCATC AATATAAA TAAGCCGGTG -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AARAAAAA MEME-5 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr4:69227075-69227155 2.1e-05 27_[+5]_45 chr1:147013218-147013298 2.1e-05 38_[+5]_34 chr2:201676397-201676477 2.1e-05 4_[+5]_68 chr20:2083064-2083144 2.1e-05 18_[+5]_54 chr1:154909551-154909631 2.1e-05 49_[+5]_23 chr21:43870277-43870357 2.1e-05 47_[+5]_25 chr7:150925752-150925832 2.1e-05 18_[+5]_54 chr8:107669911-107669991 2.1e-05 65_[+5]_7 chr12:25104841-25104921 2.1e-05 21_[+5]_51 chr7:134832698-134832778 3.1e-05 9_[+5]_63 chr1:19229152-19229232 3.1e-05 30_[+5]_42 chr17:44269113-44269193 5.5e-05 3_[+5]_69 chr7:38262269-38262349 5.5e-05 61_[+5]_11 chr19:14153942-14154022 5.5e-05 13_[+5]_59 chr14:63568921-63569001 5.5e-05 61_[+5]_11 chr17:36956236-36956316 8e-05 39_[+5]_33 chr13:76112087-76112167 8e-05 39_[+5]_33 chr5:42812095-42812175 8e-05 35_[+5]_37 chr18:21067931-21068011 0.0001 40_[+5]_32 chr3:36949643-36949723 0.0001 63_[+5]_9 chr7:104909616-104909696 0.00011 10_[+5]_62 chr9:34328753-34328833 0.00013 30_[+5]_42 chr5:139641063-139641143 0.00017 4_[+5]_68 chr10:112201532-11220161 0.00017 3_[+5]_69 chr17:62923807-62923887 0.00017 19_[+5]_53 chr2:175190702-175190782 0.00017 70_[+5]_2 chrX:47880825-47880905 0.00017 53_[+5]_19 chr3:129813196-129813276 0.00021 46_[+5]_26 chr9:33375443-33375523 0.00021 54_[+5]_18 chr19:55185653-55185733 0.00021 45_[+5]_27 chr14:92588125-92588205 0.00026 72_[+5] chr4:42659360-42659440 0.00026 64_[+5]_8 chr7:150925548-150925628 0.00026 29_[+5]_43 chr2:113299596-113299676 0.00026 72_[+5] chr22:36635615-36635695 0.00026 3_[+5]_69 chr1:169452935-169453015 0.00035 18_[+5]_54 chr3:66271364-66271444 0.00035 57_[+5]_15 chr4:13486111-13486191 0.00035 29_[+5]_43 chr9:15511084-15511164 0.00035 68_[+5]_4 chrX:119077738-119077818 0.00049 31_[+5]_41 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AARAAAAA MEME-5 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF AARAAAAA width=8 seqs=40 chr4:69227075-69227155 ( 28) AAAAAAAA 1 chr1:147013218-147013298 ( 39) AAGAAAAA 1 chr2:201676397-201676477 ( 5) AAGAAAAA 1 chr20:2083064-2083144 ( 19) AAGAAAAA 1 chr1:154909551-154909631 ( 50) AAAAAAAA 1 chr21:43870277-43870357 ( 48) AAAAAAAA 1 chr7:150925752-150925832 ( 19) AAAAAAAA 1 chr8:107669911-107669991 ( 66) AAGAAAAA 1 chr12:25104841-25104921 ( 22) AAGAAAAA 1 chr7:134832698-134832778 ( 10) AATAAAAA 1 chr1:19229152-19229232 ( 31) AATAAAAA 1 chr17:44269113-44269193 ( 4) AAAACAAA 1 chr7:38262269-38262349 ( 62) AAAACAAA 1 chr19:14153942-14154022 ( 14) AAAACAAA 1 chr14:63568921-63569001 ( 62) AAAACAAA 1 chr17:36956236-36956316 ( 40) AAGAGAAA 1 chr13:76112087-76112167 ( 40) AAAAGAAA 1 chr5:42812095-42812175 ( 36) AAAAGAAA 1 chr18:21067931-21068011 ( 41) AAGGAAAA 1 chr3:36949643-36949723 ( 64) AAAGAAAA 1 chr7:104909616-104909696 ( 11) AATACAAA 1 chr9:34328753-34328833 ( 31) AATAGAAA 1 chr5:139641063-139641143 ( 5) AAAAAAAT 1 chr10:112201532-11220161 ( 4) AAGAAAGA 1 chr17:62923807-62923887 ( 20) AAGAAAAT 1 chr2:175190702-175190782 ( 71) AAGAAAGA 1 chrX:47880825-47880905 ( 54) AAGAAAAT 1 chr3:129813196-129813276 ( 47) AAGGCAAA 1 chr9:33375443-33375523 ( 55) AAGGCAAA 1 chr19:55185653-55185733 ( 46) AAAGCAAA 1 chr14:92588125-92588205 ( 73) AATAAAAT 1 chr4:42659360-42659440 ( 65) AAAGGAAA 1 chr7:150925548-150925628 ( 30) AATAAAGA 1 chr2:113299596-113299676 ( 73) AAGGGAAA 1 chr22:36635615-36635695 ( 4) AAGGGAAA 1 chr1:169452935-169453015 ( 19) AAAACAGA 1 chr3:66271364-66271444 ( 58) AAGACAGA 1 chr4:13486111-13486191 ( 30) AAGAAGAA 1 chr9:15511084-15511164 ( 69) AAGAAGAA 1 chrX:119077738-119077818 ( 32) AATATAAA 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AARAAAAA MEME-5 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 9.77545 E= 8.6e+001 207 -1197 -1197 -1197 207 -1197 -1197 -1197 66 -1197 72 -31 175 -1197 -45 -1197 121 -12 -64 -312 200 -1197 -245 -1197 188 -1197 -113 -1197 192 -1197 -1197 -112 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AARAAAAA MEME-5 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 40 E= 8.6e+001 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.375000 0.000000 0.450000 0.175000 0.800000 0.000000 0.200000 0.000000 0.550000 0.250000 0.175000 0.025000 0.950000 0.000000 0.050000 0.000000 0.875000 0.000000 0.125000 0.000000 0.900000 0.000000 0.000000 0.100000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AARAAAAA MEME-5 regular expression -------------------------------------------------------------------------------- AA[GA][AG][AC]AAA -------------------------------------------------------------------------------- Time 19.11 secs. ******************************************************************************** ******************************************************************************** SUMMARY OF MOTIFS ******************************************************************************** -------------------------------------------------------------------------------- Combined block diagrams: non-overlapping sites with p-value < 0.0001 -------------------------------------------------------------------------------- SEQUENCE NAME COMBINED P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr1:167191643-167191723 3.58e-01 80 chr19:55185653-55185733 2.12e-02 31_[+1(6.71e-05)]_41 chr1:25758761-25758841 7.34e-02 18_[+1(4.05e-05)]_37_[+1(2.11e-05)]_\ 9 chr3:72201905-72201985 1.44e-01 80 chr8:356903-356983 1.66e-01 80 chr11:9952576-9952656 1.18e-03 17_[+2(2.68e-05)]_27_[+1(6.71e-05)]_\ 20 chrX:152419857-152419937 1.49e-01 80 chr7:104909616-104909696 9.09e-02 80 chr14:52118269-52118349 5.42e-02 50_[+4(1.68e-05)]_22 chr6:83073339-83073419 6.01e-01 80 chr12:120763373-12076345 8.79e-02 80 chrX:47880825-47880905 2.66e-02 80 chr7:99104180-99104260 3.41e-03 80 chr1:1624233-1624313 4.87e-02 43_[+3(2.39e-05)]_29 chr11:66034861-66034941 6.20e-01 80 chr12:46979763-46979843 5.58e-03 24_[+1(4.05e-05)]_35_[+3(2.39e-05)]_\ 5 chr7:44078884-44078964 2.69e-01 15_[+2(7.46e-05)]_57 chr7:44152385-44152465 2.42e-01 80 chr8:17013341-17013421 7.91e-01 80 chr1:118277851-118277931 4.48e-02 80 chr9:135285399-135285479 4.65e-01 80 chr6:90650296-90650376 6.75e-02 20_[+1(4.05e-05)]_52 chr12:56224449-56224529 9.52e-01 80 chr2:159216391-159216471 4.50e-01 80 chr2:175190702-175190782 6.58e-02 80 chr14:63568921-63569001 8.72e-03 61_[+5(5.51e-05)]_11 chr17:62923807-62923887 3.70e-03 49_[+1(2.11e-05)]_23 chr19:50268857-50268937 5.87e-01 80 chr15:50296034-50296114 3.65e-03 10_[+1(6.71e-05)]_62 chr9:33375443-33375523 6.69e-02 80 chr2:86947255-86947335 7.86e-01 80 chr10:112201532-11220161 2.09e-02 80 chr14:21944642-21944722 7.66e-01 80 chr10:27099511-27099591 8.93e-02 44_[+1(2.11e-05)]_28 chr5:150326181-150326261 5.36e-01 80 chr1:15946938-15947018 8.43e-03 61_[+1(4.05e-05)]_11 chr8:95907968-95908048 7.85e-03 51_[+1(2.11e-05)]_21 chr16:75682556-75682636 1.03e-01 2_[+3(8.01e-05)]_70 chr9:33391526-33391606 6.93e-01 80 chrX:43513977-43514057 3.96e-01 80 chr9:140444849-140444929 1.71e-02 28_[+1(2.11e-05)]_44 chr16:4511397-4511477 2.93e-01 80 chr19:35739421-35739501 9.92e-01 80 chrX:109473158-109473238 1.23e-05 18_[+2(2.68e-05)]_13_[+4(1.68e-05)]_\ 6_[+1(6.71e-05)]_19 chr1:174933773-174933853 2.85e-03 54_[+1(2.11e-05)]_7_[+2(7.46e-05)]_\ 3 chr1:43609290-43609370 2.02e-02 80 chr19:41104205-41104285 6.04e-02 80 chr10:99078862-99078942 3.98e-01 80 chr9:130538748-130538828 6.29e-02 47_[+3(2.39e-05)]_25 chr19:49649556-49649636 1.85e-01 58_[+2(2.68e-05)]_14 chr1:46519592-46519672 9.83e-02 43_[+1(4.05e-05)]_29 chr8:124553498-124553578 1.52e-01 80 chr5:89854408-89854488 5.94e-01 80 chr4:174256334-174256414 9.01e-03 49_[+1(6.71e-05)]_23 chr12:25104841-25104921 1.92e-02 21_[+5(2.14e-05)]_51 chr19:49653060-49653140 8.66e-02 15_[+3(5.00e-05)]_57 chr2:217277408-217277488 3.58e-02 71_[+2(7.46e-05)]_1 chr11:66336087-66336167 1.28e-02 22_[+1(4.05e-05)]_50 chr1:1624434-1624514 1.46e-01 5_[+2(2.68e-05)]_67 chr5:42812095-42812175 2.97e-02 35_[+5(7.98e-05)]_37 chr7:100084917-100084997 4.81e-02 80 chr17:7387391-7387471 5.71e-01 80 chr14:39901484-39901564 3.70e-01 80 chr10:112624559-11262463 9.15e-02 56_[+1(4.05e-05)]_16 chr4:90032278-90032358 8.32e-03 12_[+1(2.11e-05)]_60 chr13:76112087-76112167 1.84e-01 39_[+5(7.98e-05)]_33 chr2:220589530-220589610 4.03e-03 61_[+1(4.05e-05)]_11 chr15:65476788-65476868 2.64e-01 80 chr14:57046356-57046436 7.75e-01 80 chr22:39052496-39052576 4.17e-01 80 chr8:107669911-107669991 3.17e-02 65_[+5(2.14e-05)]_7 chr15:44975605-44975685 3.29e-04 15_[+4(1.68e-05)]_25_[+1(2.11e-05)]_\ 24 chr22:36635615-36635695 1.41e-02 80 chr13:76123730-76123810 1.17e-01 80 chr11:72525234-72525314 2.74e-01 80 chr7:21985632-21985712 6.98e-01 80 chrX:47077913-47077993 6.57e-01 80 chr7:2595226-2595306 8.21e-02 6_[+4(3.14e-05)]_66 chr12:54763029-54763109 2.46e-01 80 chr7:22748019-22748099 1.17e-01 23_[+1(4.05e-05)]_49 chr13:115078850-11507893 2.69e-01 80 chr17:53653975-53654055 4.00e-02 50_[+3(9.91e-05)]_22 chr16:85222595-85222675 1.25e-02 11_[+1(2.11e-05)]_61 chrX:53024931-53025011 3.54e-01 80 chr19:14153942-14154022 2.64e-02 13_[+5(5.51e-05)]_59 chr20:48669267-48669347 2.41e-01 80 chr16:70099988-70100068 9.58e-01 80 chr7:105226394-105226474 6.18e-01 80 chr17:7589674-7589754 2.94e-01 80 chr5:173345050-173345130 5.86e-01 80 chr11:125933049-12593312 6.09e-01 80 chr7:38262269-38262349 1.06e-02 53_[+1(6.71e-05)]_[+5(5.51e-05)]_11 chrX:48596001-48596081 1.21e-01 54_[+3(2.39e-05)]_18 chr15:48624172-48624252 1.26e-02 80 chr8:86951782-86951862 2.90e-01 80 chr9:15511084-15511164 2.08e-01 80 chr4:13486111-13486191 4.81e-01 80 chr14:75348500-75348580 1.49e-01 29_[+3(5.00e-05)]_43 chr14:39736408-39736488 1.85e-01 80 chr3:50359013-50359093 7.38e-01 80 chr18:19315648-19315728 4.78e-06 [+2(2.68e-05)]_13_[+4(1.68e-05)]_25_\ [+1(2.11e-05)]_18 chr20:8978537-8978617 7.67e-01 80 chr2:74007263-74007343 2.91e-03 19_[+4(3.14e-05)]_7_[+1(2.11e-05)]_\ 38 chr14:104410129-10441020 5.01e-02 22_[+1(4.05e-05)]_50 chr7:150925752-150925832 8.51e-02 6_[+5(5.51e-05)]_4_[+5(2.14e-05)]_\ 54 chrX:47420768-47420848 1.04e-01 47_[+2(7.46e-05)]_25 chr1:1677817-1677897 5.62e-03 70_[+3(5.00e-05)]_2 chr19:47200971-47201051 1.74e-01 [+3(8.01e-05)]_72 chr21:43870277-43870357 9.58e-03 46_[+5(2.14e-05)]_26 chr2:87303633-87303713 9.54e-01 80 chrX:118827246-118827326 9.54e-03 4_[+3(5.00e-05)]_15_[+2(7.46e-05)]_\ 45 chr3:160473049-160473129 3.25e-02 80 chr11:129872520-12987260 3.99e-03 80 chr10:99094567-99094647 6.79e-01 80 chr5:133862609-133862689 1.44e-01 80 chr20:524584-524664 3.69e-01 80 chr1:205718065-205718145 8.18e-01 80 chrX:19002635-19002715 2.73e-01 80 chr3:13690047-13690127 4.24e-01 80 chr20:814338-814418 2.25e-01 80 chr12:106696364-10669644 6.57e-01 80 chr1:154909551-154909631 6.20e-03 49_[+5(2.14e-05)]_23 chr2:113299596-113299676 4.03e-02 80 chr1:167729349-167729429 4.92e-01 80 chr10:123822896-12382297 9.64e-04 38_[+2(9.59e-05)]_34 chr7:150925548-150925628 1.37e-02 80 chrX:47050099-47050179 6.50e-01 80 chr2:120301828-120301908 9.14e-01 80 chr12:125391358-12539143 3.80e-02 80 chr4:42659360-42659440 5.09e-02 80 chrX:48858764-48858844 8.23e-01 80 chr10:73079582-73079662 5.37e-02 80 chr11:85913849-85913929 2.42e-01 80 chr7:2394036-2394116 5.68e-01 80 chr19:49653705-49653785 2.84e-02 8_[+3(8.01e-05)]_64 chr20:32581481-32581561 6.88e-01 80 chr5:64920016-64920096 6.82e-02 63_[+1(4.05e-05)]_9 chr1:110361109-110361189 5.80e-01 80 chr1:84464905-84464985 5.24e-01 80 chr20:53710946-53711026 1.51e-01 21_[+1(4.05e-05)]_51 chr11:63606179-63606259 2.52e-01 57_[+2(9.59e-05)]_15 chr22:38199695-38199775 4.87e-01 80 chr18:3037573-3037653 3.99e-02 22_[+1(4.05e-05)]_50 chr7:99724839-99724919 1.42e-02 58_[+4(5.24e-05)]_14 chr14:45603532-45603612 9.00e-01 80 chr19:33161015-33161095 9.14e-02 53_[+1(2.11e-05)]_19 chr15:65117993-65118073 1.87e-01 80 chr16:29973137-29973217 3.49e-01 80 chrX:119077738-119077818 1.13e-01 80 chr16:15068679-15068759 7.66e-01 80 chr1:6661286-6661366 4.68e-02 27_[+1(4.05e-05)]_45 chr12:33674078-33674158 1.16e-05 14_[+2(2.68e-05)]_13_[+4(1.68e-05)]_\ 6_[+1(6.71e-05)]_23 chr17:77809984-77810064 2.23e-03 41_[+2(2.68e-05)]_10_[+1(4.05e-05)]_\ 13 chr3:152944785-152944865 4.45e-02 51_[+1(2.11e-05)]_21 chr10:127511937-12751201 7.04e-01 80 chr20:2083064-2083144 5.66e-03 18_[+5(2.14e-05)]_54 chr1:19229152-19229232 8.61e-02 30_[+5(3.05e-05)]_42 chr17:62103161-62103241 3.22e-02 32_[+1(4.05e-05)]_40 chr7:102678687-102678767 7.49e-06 6_[+2(2.68e-05)]_13_[+4(1.68e-05)]_\ 14_[+1(2.11e-05)]_23 chr7:127087563-127087643 4.50e-02 80 chr5:148737228-148737308 2.22e-01 80 chr11:58538535-58538615 6.86e-02 43_[+2(2.68e-05)]_29 chr10:99400301-99400381 7.16e-02 80 chr17:17140609-17140689 2.45e-01 80 chr19:6737368-6737448 6.77e-03 8_[+2(2.68e-05)]_64 chr14:92588125-92588205 9.17e-02 80 chr8:74152844-74152924 7.38e-03 57_[+3(2.39e-05)]_15 chr10:104677812-10467789 8.43e-02 17_[+3(2.39e-05)]_55 chr3:66271364-66271444 3.08e-01 80 chr19:50179813-50179893 3.35e-01 80 chr6:110501012-110501092 4.85e-01 80 chr7:66460649-66460729 1.80e-01 80 chr21:19192040-19192120 2.03e-01 80 chr17:65990729-65990809 2.70e-02 70_[+1(4.05e-05)]_2 chr9:34328753-34328833 9.93e-03 80 chr1:169452935-169453015 2.53e-01 80 chr1:155658676-155658756 1.19e-01 80 chr17:66453976-66454056 1.77e-03 53_[+2(7.46e-05)]_19 chr7:100887704-100887784 5.24e-03 80 chrX:48754492-48754572 2.78e-01 51_[+3(8.01e-05)]_21 chr1:6052138-6052218 5.10e-02 62_[+4(5.24e-05)]_10 chr7:1094828-1094908 5.81e-03 14_[+1(2.11e-05)]_58 chr5:180671268-180671348 4.64e-01 80 chr7:43909106-43909186 1.80e-01 29_[+2(7.46e-05)]_43 chr18:11987829-11987909 1.10e-01 80 chr7:99284050-99284130 3.18e-05 26_[+2(2.68e-05)]_27_[+1(6.71e-05)]_\ 11 chr20:42219368-42219448 3.34e-01 80 chr3:36949643-36949723 4.69e-02 80 chr11:109811672-10981175 8.83e-02 10_[+1(2.11e-05)]_62 chrX:48755366-48755446 2.11e-02 7_[+2(7.46e-05)]_65 chr8:26240437-26240517 5.23e-02 80 chr10:73079380-73079460 9.66e-04 23_[+4(1.68e-05)]_5_[+1(4.05e-05)]_\ 36 chr3:185827026-185827106 5.42e-01 80 chr15:72766016-72766096 4.61e-02 20_[+1(4.05e-05)]_52 chr4:73712296-73712376 1.50e-04 16_[+4(1.68e-05)]_25_[+1(2.11e-05)]_\ 23 chr11:45921465-45921545 4.27e-01 80 chr18:21067931-21068011 8.97e-02 80 chr19:36869922-36870002 3.57e-01 80 chr6:160114478-160114558 7.71e-01 80 chr1:8586061-8586141 3.97e-01 80 chr19:55964535-55964615 1.30e-01 80 chr1:159787477-159787557 9.19e-01 80 chr11:62475033-62475113 7.52e-02 4_[+2(2.68e-05)]_68 chr10:22802908-22802988 1.09e-01 24_[+1(4.05e-05)]_48 chr5:139641063-139641143 3.60e-02 80 chr11:65260364-65260444 3.43e-02 24_[+3(2.39e-05)]_48 chr6:33167856-33167936 2.57e-03 9_[+2(2.68e-05)]_30_[+1(4.05e-05)]_\ 25 chr19:45996578-45996658 1.46e-02 10_[+1(2.11e-05)]_62 chr7:87849498-87849578 8.08e-02 80 chr4:141334911-141334991 4.47e-04 18_[+2(2.68e-05)]_27_[+1(6.71e-05)]_\ 19 chr2:44314506-44314586 1.82e-01 80 chr19:55678289-55678369 3.31e-01 80 chr12:48803867-48803947 1.90e-02 23_[+1(4.05e-05)]_49 chr2:240240174-240240254 7.74e-01 80 chr11:47290722-47290802 2.46e-01 80 chr19:30335313-30335393 4.52e-04 80 chrX:48937485-48937565 1.15e-01 56_[+1(4.05e-05)]_16 chr19:48281750-48281830 9.48e-02 80 chr2:201676397-201676477 1.14e-01 4_[+5(2.14e-05)]_68 chr21:44394188-44394268 6.35e-01 80 chr3:129813196-129813276 1.34e-01 80 chr6:37140132-37140212 2.98e-02 48_[+1(2.11e-05)]_24 chr19:42806779-42806859 1.89e-02 54_[+2(2.68e-05)]_18 chr22:38859488-38859568 6.35e-02 47_[+3(5.00e-05)]_25 chr16:4674510-4674590 2.70e-01 80 chr1:182284460-182284540 2.80e-02 80 chr4:104119624-104119704 1.61e-01 55_[+2(7.46e-05)]_17 chr12:56520113-56520193 2.00e-02 80 chr18:10578192-10578272 9.68e-03 46_[+3(2.39e-05)]_26 chr1:245508949-245509029 4.64e-02 60_[+1(4.05e-05)]_12 chr17:44269113-44269193 8.78e-02 3_[+5(5.51e-05)]_69 chr7:156931104-156931184 8.75e-04 29_[+1(2.11e-05)]_43 chr7:134832698-134832778 7.14e-03 9_[+5(3.05e-05)]_2_[+1(4.05e-05)]_\ 53 chr1:27853736-27853816 3.92e-02 34_[+1(2.11e-05)]_38 chr22:47487211-47487291 4.91e-01 80 chr1:147013218-147013298 1.06e-01 38_[+5(2.14e-05)]_34 chr11:57103072-57103152 9.63e-02 9_[+3(8.01e-05)]_63 chr4:77870783-77870863 1.79e-01 80 chr4:69227075-69227155 7.12e-04 26_[+5(2.14e-05)]_13_[+1(2.11e-05)]_\ 25 chr14:35008836-35008916 9.83e-02 46_[+1(4.05e-05)]_26 chr7:123387811-123387891 9.50e-02 53_[+3(9.91e-05)]_19 chr5:137673644-137673724 5.66e-01 80 chr12:120755561-12075564 3.98e-02 80 chr22:21822539-21822619 7.22e-02 80 chr8:129356300-129356380 2.07e-04 20_[+2(2.68e-05)]_27_[+1(6.71e-05)]_\ 17 chr16:2255287-2255367 2.27e-01 72_[+3(8.01e-05)] chr4:103746821-103746901 9.45e-02 80 chr17:36956236-36956316 1.95e-03 4_[+3(5.00e-05)]_27_[+5(7.98e-05)]_\ 33 chrX:49022872-49022952 6.47e-02 65_[+2(9.59e-05)]_7 chr17:34136218-34136298 1.33e-02 80 -------------------------------------------------------------------------------- ******************************************************************************** ******************************************************************************** Stopped because requested number of motifs (5) found. ******************************************************************************** CPU: c22n06.farnam.hpc.yale.internal ********************************************************************************