******************************************************************************** MEME - Motif discovery tool ******************************************************************************** MEME version 5.3.3 (Release date: Sun Feb 7 15:39:52 2021 -0800) For further information on how to interpret these results please access https://meme-suite.org/meme. To get a copy of the MEME Suite software please access https://meme-suite.org. ******************************************************************************** ******************************************************************************** REFERENCE ******************************************************************************** If you use this program in your research, please cite: Timothy L. Bailey and Charles Elkan, "Fitting a mixture model by expectation maximization to discover motifs in biopolymers", Proceedings of the Second International Conference on Intelligent Systems for Molecular Biology, pp. 28-36, AAAI Press, Menlo Park, California, 1994. ******************************************************************************** ******************************************************************************** TRAINING SET ******************************************************************************** PRIMARY SEQUENCES= ../result/final_prediction/K562/fasta/RankLinear0.6_40/FOXA1.fasta CONTROL SEQUENCES= --none-- ALPHABET= ACGT Sequence name Weight Length Sequence name Weight Length ------------- ------ ------ ------------- ------ ------ chr4:80769644-80769724 1.0000 80 chr1:75155679-75155759 1.0000 80 chr5:34246200-34246280 1.0000 80 chr16:33407385-33407465 1.0000 80 chr11:5642584-5642664 1.0000 80 chr8:146180149-146180229 1.0000 80 chr5:123935496-123935576 1.0000 80 chr14:25451991-25452071 1.0000 80 chr6:159269616-159269696 1.0000 80 chr4:147257768-147257848 1.0000 80 chr3:186324203-186324283 1.0000 80 chr4:113021007-113021087 1.0000 80 chr7:2551215-2551295 1.0000 80 chr6:106525847-106525927 1.0000 80 chr1:150450470-150450550 1.0000 80 chr4:134185558-134185638 1.0000 80 chr14:69616726-69616806 1.0000 80 chr1:157337842-157337922 1.0000 80 chr12:50635160-50635240 1.0000 80 chr3:99650062-99650142 1.0000 80 chr1:101602358-101602438 1.0000 80 chr10:112186082-11218616 1.0000 80 chr14:23265732-23265812 1.0000 80 chr4:77890825-77890905 1.0000 80 chr8:131277003-131277083 1.0000 80 chr20:22384669-22384749 1.0000 80 chr1:229645464-229645544 1.0000 80 chr4:95394187-95394267 1.0000 80 chr6:20086193-20086273 1.0000 80 chr1:22740827-22740907 1.0000 80 chr4:83806729-83806809 1.0000 80 chr12:31430183-31430263 1.0000 80 chr6:43672683-43672763 1.0000 80 chr1:47187632-47187712 1.0000 80 chr10:127702285-12770236 1.0000 80 chr6:161971465-161971545 1.0000 80 chr3:141422384-141422464 1.0000 80 chr3:138405760-138405840 1.0000 80 chr17:44836152-44836232 1.0000 80 chrX:69440347-69440427 1.0000 80 chr8:73080275-73080355 1.0000 80 chr7:150462899-150462979 1.0000 80 chr5:130648166-130648246 1.0000 80 chr6:134519312-134519392 1.0000 80 chr11:74770503-74770583 1.0000 80 chr5:180313046-180313126 1.0000 80 chr18:11923620-11923700 1.0000 80 chr14:60766857-60766937 1.0000 80 chr16:31111702-31111782 1.0000 80 chr8:5997544-5997624 1.0000 80 chr8:27316859-27316939 1.0000 80 chr2:223743155-223743235 1.0000 80 chr10:62185283-62185363 1.0000 80 chr2:106806681-106806761 1.0000 80 chr6:126063718-126063798 1.0000 80 chr3:141013755-141013835 1.0000 80 chr15:82555863-82555943 1.0000 80 chr17:19423140-19423220 1.0000 80 chr19:33488142-33488222 1.0000 80 chr21:22229401-22229481 1.0000 80 chr3:17462341-17462421 1.0000 80 chr5:132385459-132385539 1.0000 80 chr7:72772511-72772591 1.0000 80 chr15:66059429-66059509 1.0000 80 chr6:90813344-90813424 1.0000 80 chr8:129541424-129541504 1.0000 80 chr19:252947-253027 1.0000 80 chr9:128300465-128300545 1.0000 80 chr11:60138379-60138459 1.0000 80 chr6:84144350-84144430 1.0000 80 chr8:102904131-102904211 1.0000 80 chr4:111028270-111028350 1.0000 80 chr19:29049854-29049934 1.0000 80 chr2:36739524-36739604 1.0000 80 chr8:94678601-94678681 1.0000 80 chr12:120099823-12009990 1.0000 80 chr10:104723176-10472325 1.0000 80 chrX:150017600-150017680 1.0000 80 chr2:157559227-157559307 1.0000 80 chr2:209503013-209503093 1.0000 80 chr8:103343491-103343571 1.0000 80 chr7:95932586-95932666 1.0000 80 chr20:46234651-46234731 1.0000 80 chr21:43823050-43823130 1.0000 80 chr1:8121485-8121565 1.0000 80 chr12:116966993-11696707 1.0000 80 chr9:110267258-110267338 1.0000 80 chr10:45857960-45858040 1.0000 80 chr18:32509338-32509418 1.0000 80 chr2:234130541-234130621 1.0000 80 chr11:46872560-46872640 1.0000 80 chr17:77810008-77810088 1.0000 80 chr12:21504049-21504129 1.0000 80 chr12:8059828-8059908 1.0000 80 chr5:126219638-126219718 1.0000 80 chr1:180784517-180784597 1.0000 80 chr11:93811185-93811265 1.0000 80 chr7:31448150-31448230 1.0000 80 chr11:20499098-20499178 1.0000 80 chr12:32599391-32599471 1.0000 80 chr1:181129628-181129708 1.0000 80 chr8:86957068-86957148 1.0000 80 chr12:47710416-47710496 1.0000 80 chr8:99539058-99539138 1.0000 80 chr1:206236453-206236533 1.0000 80 chr6:147513559-147513639 1.0000 80 chr8:25517993-25518073 1.0000 80 chr1:65784148-65784228 1.0000 80 chr1:154159364-154159444 1.0000 80 chr6:133285443-133285523 1.0000 80 chr3:183048845-183048925 1.0000 80 chr16:3696424-3696504 1.0000 80 chr12:30916188-30916268 1.0000 80 chr7:24944693-24944773 1.0000 80 chr6:36991269-36991349 1.0000 80 chr3:152944743-152944823 1.0000 80 chr2:179058357-179058437 1.0000 80 chr18:33429406-33429486 1.0000 80 chr17:75118042-75118122 1.0000 80 chr15:58330348-58330428 1.0000 80 chr3:58457217-58457297 1.0000 80 chr6:71100039-71100119 1.0000 80 chr6:136928424-136928504 1.0000 80 chr2:176800127-176800207 1.0000 80 chr15:79012566-79012646 1.0000 80 chr6:7591211-7591291 1.0000 80 chr2:114367618-114367698 1.0000 80 chr4:174529846-174529926 1.0000 80 chr2:171202275-171202355 1.0000 80 chr4:38874421-38874501 1.0000 80 chr18:20681905-20681985 1.0000 80 chr17:61117829-61117909 1.0000 80 chr5:148039385-148039465 1.0000 80 chr9:90400665-90400745 1.0000 80 chr6:39653125-39653205 1.0000 80 chr16:75121338-75121418 1.0000 80 chr10:126635628-12663570 1.0000 80 chr11:13950556-13950636 1.0000 80 chr9:128046980-128047060 1.0000 80 chr1:15954591-15954671 1.0000 80 chr6:34921520-34921600 1.0000 80 chr6:119451239-119451319 1.0000 80 chr1:175703049-175703129 1.0000 80 chr9:125293604-125293684 1.0000 80 chr7:36636999-36637079 1.0000 80 chr5:162806746-162806826 1.0000 80 chr2:205348340-205348420 1.0000 80 chr20:30913768-30913848 1.0000 80 chr7:22748040-22748120 1.0000 80 chr10:11645054-11645134 1.0000 80 chr5:19099488-19099568 1.0000 80 chr12:65050354-65050434 1.0000 80 chr13:24230994-24231074 1.0000 80 chr8:42400413-42400493 1.0000 80 chr14:88490840-88490920 1.0000 80 chr2:149259238-149259318 1.0000 80 chr16:69251545-69251625 1.0000 80 chr5:82561157-82561237 1.0000 80 chr1:144881510-144881590 1.0000 80 chr15:91056911-91056991 1.0000 80 chr16:24998323-24998403 1.0000 80 chr1:116963159-116963239 1.0000 80 chr11:75460030-75460110 1.0000 80 chr19:41427116-41427196 1.0000 80 chr4:175241887-175241967 1.0000 80 chr10:35331939-35332019 1.0000 80 chr11:20111811-20111891 1.0000 80 chr2:54799570-54799650 1.0000 80 chr5:65131196-65131276 1.0000 80 chr5:74991932-74992012 1.0000 80 chr8:126676795-126676875 1.0000 80 chr6:161223124-161223204 1.0000 80 chr1:246445119-246445199 1.0000 80 chr10:80218911-80218991 1.0000 80 chr7:12991278-12991358 1.0000 80 chr15:58025104-58025184 1.0000 80 chr12:9787817-9787897 1.0000 80 chr7:29762825-29762905 1.0000 80 chr4:77129656-77129736 1.0000 80 chr8:59425949-59426029 1.0000 80 chr17:73068150-73068230 1.0000 80 chr13:50819360-50819440 1.0000 80 chr17:56465359-56465439 1.0000 80 chr10:123822872-12382295 1.0000 80 chr12:12551416-12551496 1.0000 80 chr3:142034872-142034952 1.0000 80 chr13:91129349-91129429 1.0000 80 chr5:81254097-81254177 1.0000 80 chr3:33109112-33109192 1.0000 80 chr1:54422549-54422629 1.0000 80 chr10:62042786-62042866 1.0000 80 chr1:198638384-198638464 1.0000 80 chr1:142821823-142821903 1.0000 80 chr11:59554593-59554673 1.0000 80 chr19:20344158-20344238 1.0000 80 chr9:71123521-71123601 1.0000 80 chr1:167713036-167713116 1.0000 80 chr8:142238704-142238784 1.0000 80 chrX:46907612-46907692 1.0000 80 chr11:62316448-62316528 1.0000 80 chr10:73653858-73653938 1.0000 80 chr1:246276893-246276973 1.0000 80 chr22:23215691-23215771 1.0000 80 chr3:41309628-41309708 1.0000 80 chr14:59915614-59915694 1.0000 80 chr2:192502665-192502745 1.0000 80 chr8:129356346-129356426 1.0000 80 chr8:66629754-66629834 1.0000 80 chr12:104198858-10419893 1.0000 80 chr10:115626947-11562702 1.0000 80 chr1:174842021-174842101 1.0000 80 chr21:44427046-44427126 1.0000 80 chr6:134279186-134279266 1.0000 80 chr5:131636379-131636459 1.0000 80 chr11:65138806-65138886 1.0000 80 chr1:26216949-26217029 1.0000 80 chr3:34053751-34053831 1.0000 80 chr2:205935791-205935871 1.0000 80 chr22:23001266-23001346 1.0000 80 chr3:150165697-150165777 1.0000 80 chr1:206554430-206554510 1.0000 80 chr5:180096385-180096465 1.0000 80 chr5:10494745-10494825 1.0000 80 chr16:19000462-19000542 1.0000 80 chr2:200767332-200767412 1.0000 80 chrX:119683983-119684063 1.0000 80 chr8:8917253-8917333 1.0000 80 chr6:158246628-158246708 1.0000 80 chr5:10507768-10507848 1.0000 80 chr6:97079305-97079385 1.0000 80 chr10:76951966-76952046 1.0000 80 chr1:28306226-28306306 1.0000 80 chr7:137729787-137729867 1.0000 80 chr3:197159785-197159865 1.0000 80 chr2:47306221-47306301 1.0000 80 chr1:142876537-142876617 1.0000 80 chr19:49078151-49078231 1.0000 80 chr3:69882776-69882856 1.0000 80 chr8:99803241-99803321 1.0000 80 chr10:61833343-61833423 1.0000 80 chr15:49144330-49144410 1.0000 80 chr3:88124801-88124881 1.0000 80 chr8:15559453-15559533 1.0000 80 chr10:121593798-12159387 1.0000 80 chr13:99628305-99628385 1.0000 80 chr4:113034368-113034448 1.0000 80 chr6:42535126-42535206 1.0000 80 chr7:123235078-123235158 1.0000 80 chr10:14223357-14223437 1.0000 80 chr2:152709922-152710002 1.0000 80 ******************************************************************************** ******************************************************************************** COMMAND LINE SUMMARY ******************************************************************************** This information can also be useful in the event you wish to report a problem with the MEME software. command: meme -oc ../result/final_prediction/K562/inference_raw/MEME/RankLinear0.6_40_FOXA1/ -dna -nmotifs 5 -w 8 -maxsize 250000 -nostatus ../result/final_prediction/K562/fasta/RankLinear0.6_40/FOXA1.fasta model: mod= zoops nmotifs= 5 evt= inf objective function: em= E-value of product of p-values starts= E-value of product of p-values strands: + width: minw= 8 maxw= 8 nsites: minsites= 2 maxsites= 250 wnsites= 0.8 theta: spmap= uni spfuzz= 0.5 em: prior= dirichlet b= 0.01 maxiter= 50 distance= 1e-05 trim: wg= 11 ws= 1 endgaps= yes data: n= 20000 N= 250 sample: seed= 0 hsfrac= 0 searchsize= 20000 norand= no csites= 1000 Letter frequencies in dataset: A 0.289 C 0.208 G 0.215 T 0.287 Background letter frequencies (from file dataset with add-one prior applied): A 0.289 C 0.208 G 0.215 T 0.287 Background model order: 0 ******************************************************************************** ******************************************************************************** MOTIF TGTTTACW MEME-1 width = 8 sites = 158 llr = 1101 E-value = 1.3e-089 ******************************************************************************** -------------------------------------------------------------------------------- Motif TGTTTACW MEME-1 Description -------------------------------------------------------------------------------- Simplified A :21::826 pos.-specific C ::::::81 probability G :8:222:: matrix T a:988::3 bits 2.3 2.0 1.8 * 1.6 * * Relative 1.4 *** * Entropy 1.1 ******* (10.1 bits) 0.9 ******* 0.7 ******* 0.5 ******** 0.2 ******** 0.0 -------- Multilevel TGTTTACA consensus A T sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGTTTACW MEME-1 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr3:88124801-88124881 58 2.53e-05 TTTTTGTGTT TGTTTACA TTTGAGCCTG chr3:69882776-69882856 63 2.53e-05 TGTGGTTCTC TGTTTACA CTGTATGTGG chr10:76951966-76952046 49 2.53e-05 CCCTGAACTC TGTTTACA CAAGGCTGGT chr6:158246628-158246708 49 2.53e-05 CTCATTTCCA TGTTTACA TTGTGACAAA chr5:81254097-81254177 53 2.53e-05 gccctgctct tgtttaca ctgccggttt chr7:29762825-29762905 37 2.53e-05 CTCACTCCTT TGTTTACA CAGAGATGTG chr5:65131196-65131276 16 2.53e-05 acagtagctt tgtttaca atggcaaagc chr2:54799570-54799650 1 2.53e-05 . TGTTTACA GAGATAACAG chr10:35331939-35332019 23 2.53e-05 gccacacctt tgtttaca gaagccttct chr12:65050354-65050434 62 2.53e-05 CAGTGAAAGT TGTTTACA CAAGCCTGAG chr7:22748040-22748120 3 2.53e-05 ct tgtttaca ctgccggttt chr9:128046980-128047060 13 2.53e-05 ttatagagtg tgtttaca caaacttagg chr18:33429406-33429486 44 2.53e-05 gccctgccgt tgtttaca ctgcctattt chr6:147513559-147513639 33 2.53e-05 caagcacagt tgtttaca tattatctac chr17:77810008-77810088 36 2.53e-05 GCTGCGCCCT TGTTTACA CAGCGGCAAA chr12:116966993-11696707 62 2.53e-05 GCTGAGGTCA TGTTTACA CCAAGCAAAT chr19:29049854-29049934 23 2.53e-05 ctaaagtcca tgtttaca ttagggtttc chr14:60766857-60766937 73 2.53e-05 GGCTGCCTGT TGTTTACA chr5:180313046-180313126 44 2.53e-05 ctggctgctt tgtttaca cagtgagcca chr1:22740827-22740907 7 2.53e-05 GCTCCG TGTTTACA CAAGGACTCT chr10:112186082-11218616 31 2.53e-05 ccagccatag tgtttaca tagtcagaaa chr14:25451991-25452071 18 2.53e-05 ACAAGATCTG TGTTTACA CAAGTTTATT chr11:5642584-5642664 64 2.53e-05 TAGCCACTCC TGTTTACA TAGAGCTCT chr10:61833343-61833423 56 5.05e-05 GACACAGGAG TGTTTACT CTGGAAGACT chr7:137729787-137729867 15 5.05e-05 gtgaaactgt tgtttact cattttcaat chr5:10507768-10507848 25 5.05e-05 tgacagtctt tgtttact tgggcccttg chr1:26216949-26217029 22 5.05e-05 taaacaggct tgtttact tatgttgacc chr9:71123521-71123601 23 5.05e-05 TGCTGGATCT TGTTTACT CAGCCTGAAA chr11:59554593-59554673 22 5.05e-05 GCCAAGTGAG TGTTTACT TAGAACTGAG chr1:116963159-116963239 58 5.05e-05 TCCAGCTTCT TGTTTACT CTGTGTAAAT chr2:205348340-205348420 60 5.05e-05 GCCTCTTCAC TGTTTACT GATTGTATCA chr7:36636999-36637079 26 5.05e-05 TTACAATGTG TGTTTACT GTAGGATGAG chr17:61117829-61117909 33 5.05e-05 TGAGACGAGA TGTTTACT TAAGCCACAC chr2:176800127-176800207 55 5.05e-05 TACTTCTAGT TGTTTACT AAAGGAAGCC chr3:152944743-152944823 4 5.05e-05 att tgtttact ttaagagtaa chr6:36991269-36991349 46 5.05e-05 CAACCCCCTC TGTTTACT CTGCAAACAG chr5:126219638-126219718 35 5.05e-05 AGTCTCACAG TGTTTACT CACTTGGGCT chr1:8121485-8121565 34 5.05e-05 AAACATGAAG TGTTTACT TTCCTCCATG chr6:126063718-126063798 21 5.05e-05 TGTAGTCTGC TGTTTACT TTGGCCTTGA chr6:106525847-106525927 7 5.05e-05 TAAATG TGTTTACT TTTTTCACTG chr16:33407385-33407465 22 5.05e-05 gggggcagtt tgtttact cgttgcttta chr13:99628305-99628385 28 8.77e-05 CTTCTTATCT TGTTTACC CTGCTGGAAG chr10:121593798-12159387 66 8.77e-05 aatgactcag tgtgtaca aaggatc chr15:49144330-49144410 63 8.77e-05 GTAGAGGAAG TGTGTACA CAAGTGGCCT chr8:99803241-99803321 41 8.77e-05 atgatatgat tgtttacc tagaaaaccc chr2:47306221-47306301 42 8.77e-05 cttcagtgtg tgtttacc aagaacaaag chr5:131636379-131636459 62 8.77e-05 GAGGAGTCTG TGTTTACC CCTGCGGGAG chr1:198638384-198638464 2 8.77e-05 T TGTTTACC CTGTCACCAC chr12:12551416-12551496 6 8.77e-05 AGAGA TGTTTACC ATGTCCTCCC chr11:20111811-20111891 31 8.77e-05 GAAGCCCAGC TGTGTACA CATGGTGGGG chr2:171202275-171202355 57 8.77e-05 aatggggcaa tgtgtaca cagacaaaca chr4:174529846-174529926 43 8.77e-05 cccgctgctt tgtttacc taagcgagcc chr3:183048845-183048925 57 8.77e-05 accaggccat tgtttacc ttgccctaag chr12:21504049-21504129 5 8.77e-05 TAAA TGTGTACA AGGCACTATG chrX:150017600-150017680 38 8.77e-05 ATTCAACACC TGTGTACA CAGTTAGGCG chr2:36739524-36739604 19 8.77e-05 CAGAGGTAAG TGTGTACA CATGGCCCTT chr5:130648166-130648246 19 8.77e-05 caggctgctt tgtttacc taagcaagcc chr3:141422384-141422464 42 8.77e-05 atgatatcat tgtttacc tagaaaacac chr4:83806729-83806809 19 8.77e-05 TCTTTCTCAG TGTTTACC TTTGAACTCC chr8:15559453-15559533 23 1.26e-04 tactaagtca tgttgaca cagatggtct chr5:180096385-180096465 44 1.26e-04 GAAGTTTGTT TGTTGACA CTATCTGTGG chr1:174842021-174842101 39 1.26e-04 ACTTTGTGAA TGTTTGCA TAGAGTTACC chr10:115626947-11562702 43 1.26e-04 gagccaatct tgtttgca caccttttaa chr17:56465359-56465439 23 1.26e-04 CTGATATTTC TGTTGACA CAGTGACTAT chr6:161223124-161223204 45 1.26e-04 ggaattttct tgttgaca aaggacaggc chr1:144881510-144881590 12 1.26e-04 TTGATAGCGT TGTTTGCA TTGTGACAGC chr2:149259238-149259318 41 1.26e-04 GGCTGACCTC TGTTGACA TAGCTGACCA chr13:24230994-24231074 13 1.26e-04 GCATTTTCAG TGTTTGCA CAGCTGTGCT chr11:13950556-13950636 12 1.26e-04 tacttcatag tgttgaca taaggattaa chr18:20681905-20681985 16 1.26e-04 TCTGAAATCT TGTTGACA CAGGCATGAA chr3:58457217-58457297 39 1.26e-04 GTGAGTCAGA TGTTTGCA CAGAAGGCTG chr2:223743155-223743235 17 1.26e-04 TCTGCAGCCT TGTTGACA CTCCTGACAA chr5:34246200-34246280 27 1.26e-04 tgtgaaatca tgttgaca cagaTGGCCT chr1:246276893-246276973 69 1.60e-04 tatcactttc tatttaca cagc chr1:54422549-54422629 50 1.60e-04 ACAGCAGCTT TATTTACA ATGCAATTAA chr2:179058357-179058437 48 1.60e-04 TCTGTACAAA TATTTACA TTACCCCGTC chr6:133285443-133285523 20 1.60e-04 GGGTGGGCAA TATTTACA CTGGTGACTC chr21:43823050-43823130 31 1.60e-04 tatatggttc tatttaca taaggctcaa chr4:111028270-111028350 41 1.60e-04 GGGACCTTGC TATTTACA CAAGCAGCTT chr6:20086193-20086273 43 1.60e-04 gggtggacaa tatttaca taagaacaca chr12:50635160-50635240 32 1.60e-04 CAAGGCAAGG TATTTACA TTGTGGTTAG chr1:157337842-157337922 5 1.60e-04 GTCC TATTTACA AAGAGGAGAT chr14:69616726-69616806 43 1.78e-04 TTAACACAGC TGTGTACT CATAATGGAA chr10:14223357-14223437 25 2.51e-04 CGCTGCCCCG TGTTTGCT CAGAAGACCT chr5:10494745-10494825 41 2.51e-04 cccacaagtg tgttgact caaggccttt chr11:65138806-65138886 69 2.51e-04 TTATTTAACA TGTTTGCT CAAG chr3:142034872-142034952 15 2.51e-04 ttacatcatt tgtttaaa tatacaaaca chr17:73068150-73068230 45 2.51e-04 TTTTGGTGGA TGTTGACT TAGTTCATGA chr16:24998323-24998403 21 2.51e-04 TTTTAATCAC TGTTTGCT TTCTGGTCTC chr14:88490840-88490920 7 2.51e-04 gtgctg tgttgact caaggtttaa chr6:90813344-90813424 21 2.51e-04 GATGCTTTTT TGTTTGCT TTTTAAAGTA chr5:132385459-132385539 22 2.51e-04 CAGCTCGGGT TGTTTGCT CAGTGATTAA chr1:47187632-47187712 27 2.51e-04 TCTGTCTGCC TGTTTGCT TATGATCTGT chr5:123935496-123935576 43 2.51e-04 CAGACTTCCT TGTTTAAA CACTATAACA chr4:175241887-175241967 26 2.85e-04 GCTTGTATCT TATTTACT GAACCAttta chr6:39653125-39653205 60 2.85e-04 tggttgggtc tatttact cagcgaagta chr15:58330348-58330428 21 2.85e-04 CTTTCAACAG TATTTACT CAGTGTCTTC chr11:20499098-20499178 63 2.85e-04 GACGGGAGGG TATTTACT CTCCTGAGGA chr12:8059828-8059908 54 2.85e-04 TGACTCCTTT TATTTACT CAGAGTTGCT chr20:46234651-46234731 52 2.85e-04 AGCATCTGTt tatttact tacttatctg chr6:84144350-84144430 24 2.85e-04 AATTATTTCT TATTTACT CTGGGTAAAC chr15:66059429-66059509 37 2.85e-04 GGTGTGTAAA TATTTACT CAATGGATGA chr6:43672683-43672763 48 2.85e-04 CCTAGCTTTG TATTTACT CAGCATTTGC chr4:147257768-147257848 52 2.85e-04 cctttgtcaa tatttact ttaccatttc chr6:159269616-159269696 70 2.85e-04 ttatcagtgt tatttact taa chr2:205935791-205935871 72 3.54e-04 ATAAATACAG TGTGTGCA A chr12:9787817-9787897 35 3.54e-04 ggcctaatca tgttgacc caccttcccc chr7:24944693-24944773 32 3.54e-04 taaagggctt tgtggaca catagccaga chr8:59425949-59426029 22 4.79e-04 AGTGGACAAT TATGTACA TTGACACATC chr8:126676795-126676875 61 4.79e-04 CCTATTATCT TATTTACC CATGTTTGTT chr19:33488142-33488222 27 4.79e-04 actcaacaaa tatttacc aaatgtgctg chr10:126635628-12663570 42 5.30e-04 CGAGCAAACA TATTGACA TAGCTGTTGG chr21:22229401-22229481 19 5.30e-04 ACCCTTATCT TATTTGCA CAGTACTCTG chr7:150462899-150462979 39 5.30e-04 ccccgtatct tattgaca cagcctttta chr1:28306226-28306306 49 6.10e-04 CCAGGGTTCC tgtgtaaa taagataaag chr13:50819360-50819440 60 6.10e-04 tctgactcac tgtgtaaa ccatgggtga chr5:162806746-162806826 12 6.10e-04 GCTGAGTCAC TGTGTAAA CACACTTCAA chr16:75121338-75121418 51 6.10e-04 CTCTTCTGGC TGTGTAAA CAGTGAGCTG chr6:71100039-71100119 38 6.10e-04 GCTGTTGTGA TGTTTAAC TGAAAGGCAT chr17:75118042-75118122 21 6.10e-04 CTTAAAAGGC TGTGTAAA CATGCATTAG chr1:154159364-154159444 18 6.10e-04 CAGAACTGCT TGTGTAAA CACGTAGTTA chr8:94678601-94678681 67 6.10e-04 GTAAACATTC TGTGTAAA CACCAT chr9:128300465-128300545 28 6.10e-04 ctttggttgc tgtgtaaa caacagactg chr8:5997544-5997624 73 6.10e-04 CTATTCCCTT TGTGTAAA chr8:146180149-146180229 43 6.10e-04 gtaaaccagc tgtgtaaa caagaggagg chr10:80218911-80218991 22 6.76e-04 CACTTATCTC TGTTTGAA CAATTGCTAA chr17:44836152-44836232 15 6.76e-04 TCAACAGACT TGTTGAAA CAGTGAGTCA chr1:229645464-229645544 7 6.76e-04 aacgtg tgttgaaa taagggaatG chr3:99650062-99650142 73 6.76e-04 AAACAGGCTG TGTTTGAA chr12:47710416-47710496 34 7.45e-04 AGCACACAGC TGTTTCCA TCATGCTGAC chr8:129541424-129541504 34 7.45e-04 TGGCCATTCA TGTTTCCA AGAGGCTTAT chr10:62042786-62042866 62 8.43e-04 AATAATGACT TATTTGCT TTCATTTCAC chr17:19423140-19423220 47 8.43e-04 acatgtgctg tattgact caaggtttaa chr15:82555863-82555943 39 8.43e-04 ATTAGATCAT TATTTGCT AAGTAAATAT chr4:80769644-80769724 50 8.43e-04 atgaaatggc tattgact caaggataga chr10:127702285-12770236 20 9.10e-04 ACTGGCTTTG TGTGGGCA GCTGTGTTGA chr4:77129656-77129736 48 1.02e-03 CAAGCCCGGA TGAGTACA GAGCCAGGCT chr18:32509338-32509418 28 1.02e-03 TGTAAATATT TGTTGAAT GAATCATAAG chr9:110267258-110267338 20 1.02e-03 AAAGTCATCC TGTTGAAT TTGTGACTCA chr19:49078151-49078231 17 1.15e-03 ATGGGATAAC TGATGACA TCACTGAACA chr8:142238704-142238784 28 1.15e-03 AACATCTTTG TGATGACA CAGTGATGTT chr11:93811185-93811265 8 1.15e-03 tatagta tgtttcct cctacaagaa chr7:95932586-95932666 10 1.15e-03 TAAAGTAAA TATTTGCC TTAGATAAGA chr2:157559227-157559307 35 1.15e-03 ACAACCATAC TGATGACA GGGCATTTTG chr10:11645054-11645134 2 1.23e-03 T TGTTTACG CTATTCACTA chr13:91129349-91129429 65 1.27e-03 GAGAGAAAAT TAATTACA CAGTTAAG chr2:114367618-114367698 28 1.41e-03 ccagaaatcg tgtttgac cagctgtgtg chr2:209503013-209503093 8 1.41e-03 aagtgcc tgtgtgaa agcaaatagt chr19:252947-253027 5 1.41e-03 atcg tgtttgac cagctgtgtg chr8:27316859-27316939 63 1.41e-03 TTGTTTTGTT TGTTTGAC CTGCCCTTTG chr1:142876537-142876617 12 1.67e-03 ggagtctcga tgattgct aacacagcag chr2:192502665-192502745 67 1.67e-03 aaagcttaag tgattaaa aggata chr4:38874421-38874501 43 1.67e-03 gacggtccca tatgtaaa caaagggtgt chr10:45857960-45858040 29 1.67e-03 ggagtcttgc tgattgct agcacagcag chr3:17462341-17462421 59 1.67e-03 TTCAGCTGAC TATGTAAA TAAACAAACA chr1:175703049-175703129 16 2.03e-03 GAGTCAGTTA TGAGGACA TAGCCAGGCC chr5:82561157-82561237 16 2.52e-03 TTTATCATAA TGTTTATC TTAGTTGCAA chr7:72772511-72772591 32 3.27e-03 GAGATTGCTT TGTGTATT TTGTAGGGTT -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGTTTACW MEME-1 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr3:88124801-88124881 2.5e-05 57_[+1]_15 chr3:69882776-69882856 2.5e-05 62_[+1]_10 chr10:76951966-76952046 2.5e-05 48_[+1]_24 chr6:158246628-158246708 2.5e-05 48_[+1]_24 chr5:81254097-81254177 2.5e-05 52_[+1]_20 chr7:29762825-29762905 2.5e-05 36_[+1]_36 chr5:65131196-65131276 2.5e-05 15_[+1]_57 chr2:54799570-54799650 2.5e-05 [+1]_72 chr10:35331939-35332019 2.5e-05 22_[+1]_50 chr12:65050354-65050434 2.5e-05 61_[+1]_11 chr7:22748040-22748120 2.5e-05 2_[+1]_70 chr9:128046980-128047060 2.5e-05 12_[+1]_60 chr18:33429406-33429486 2.5e-05 43_[+1]_29 chr6:147513559-147513639 2.5e-05 32_[+1]_40 chr17:77810008-77810088 2.5e-05 35_[+1]_37 chr12:116966993-11696707 2.5e-05 61_[+1]_11 chr19:29049854-29049934 2.5e-05 22_[+1]_50 chr14:60766857-60766937 2.5e-05 72_[+1] chr5:180313046-180313126 2.5e-05 43_[+1]_29 chr1:22740827-22740907 2.5e-05 6_[+1]_66 chr10:112186082-11218616 2.5e-05 30_[+1]_42 chr14:25451991-25452071 2.5e-05 17_[+1]_55 chr11:5642584-5642664 2.5e-05 63_[+1]_9 chr10:61833343-61833423 5.1e-05 55_[+1]_17 chr7:137729787-137729867 5.1e-05 14_[+1]_58 chr5:10507768-10507848 5.1e-05 24_[+1]_48 chr1:26216949-26217029 5.1e-05 21_[+1]_51 chr9:71123521-71123601 5.1e-05 22_[+1]_50 chr11:59554593-59554673 5.1e-05 21_[+1]_51 chr1:116963159-116963239 5.1e-05 57_[+1]_15 chr2:205348340-205348420 5.1e-05 59_[+1]_13 chr7:36636999-36637079 5.1e-05 25_[+1]_47 chr17:61117829-61117909 5.1e-05 32_[+1]_40 chr2:176800127-176800207 5.1e-05 54_[+1]_18 chr3:152944743-152944823 5.1e-05 3_[+1]_69 chr6:36991269-36991349 5.1e-05 45_[+1]_27 chr5:126219638-126219718 5.1e-05 34_[+1]_38 chr1:8121485-8121565 5.1e-05 33_[+1]_39 chr6:126063718-126063798 5.1e-05 20_[+1]_52 chr6:106525847-106525927 5.1e-05 6_[+1]_66 chr16:33407385-33407465 5.1e-05 21_[+1]_51 chr13:99628305-99628385 8.8e-05 27_[+1]_45 chr10:121593798-12159387 8.8e-05 65_[+1]_7 chr15:49144330-49144410 8.8e-05 62_[+1]_10 chr8:99803241-99803321 8.8e-05 40_[+1]_32 chr2:47306221-47306301 8.8e-05 41_[+1]_31 chr5:131636379-131636459 8.8e-05 61_[+1]_11 chr1:198638384-198638464 8.8e-05 1_[+1]_71 chr12:12551416-12551496 8.8e-05 5_[+1]_67 chr11:20111811-20111891 8.8e-05 30_[+1]_42 chr2:171202275-171202355 8.8e-05 56_[+1]_16 chr4:174529846-174529926 8.8e-05 42_[+1]_30 chr3:183048845-183048925 8.8e-05 56_[+1]_16 chr12:21504049-21504129 8.8e-05 4_[+1]_68 chrX:150017600-150017680 8.8e-05 37_[+1]_35 chr2:36739524-36739604 8.8e-05 18_[+1]_54 chr5:130648166-130648246 8.8e-05 18_[+1]_54 chr3:141422384-141422464 8.8e-05 41_[+1]_31 chr4:83806729-83806809 8.8e-05 18_[+1]_54 chr8:15559453-15559533 0.00013 22_[+1]_50 chr5:180096385-180096465 0.00013 43_[+1]_29 chr1:174842021-174842101 0.00013 38_[+1]_34 chr10:115626947-11562702 0.00013 42_[+1]_30 chr17:56465359-56465439 0.00013 22_[+1]_50 chr6:161223124-161223204 0.00013 44_[+1]_28 chr1:144881510-144881590 0.00013 11_[+1]_61 chr2:149259238-149259318 0.00013 40_[+1]_32 chr13:24230994-24231074 0.00013 12_[+1]_60 chr11:13950556-13950636 0.00013 11_[+1]_61 chr18:20681905-20681985 0.00013 15_[+1]_57 chr3:58457217-58457297 0.00013 38_[+1]_34 chr2:223743155-223743235 0.00013 16_[+1]_56 chr5:34246200-34246280 0.00013 26_[+1]_46 chr1:246276893-246276973 0.00016 68_[+1]_4 chr1:54422549-54422629 0.00016 49_[+1]_23 chr2:179058357-179058437 0.00016 47_[+1]_25 chr6:133285443-133285523 0.00016 19_[+1]_53 chr21:43823050-43823130 0.00016 30_[+1]_42 chr4:111028270-111028350 0.00016 40_[+1]_32 chr6:20086193-20086273 0.00016 42_[+1]_30 chr12:50635160-50635240 0.00016 31_[+1]_41 chr1:157337842-157337922 0.00016 4_[+1]_68 chr14:69616726-69616806 0.00018 42_[+1]_30 chr10:14223357-14223437 0.00025 24_[+1]_48 chr5:10494745-10494825 0.00025 40_[+1]_32 chr11:65138806-65138886 0.00025 68_[+1]_4 chr3:142034872-142034952 0.00025 14_[+1]_58 chr17:73068150-73068230 0.00025 44_[+1]_28 chr16:24998323-24998403 0.00025 20_[+1]_52 chr14:88490840-88490920 0.00025 6_[+1]_66 chr6:90813344-90813424 0.00025 20_[+1]_52 chr5:132385459-132385539 0.00025 21_[+1]_51 chr1:47187632-47187712 0.00025 26_[+1]_46 chr5:123935496-123935576 0.00025 42_[+1]_30 chr4:175241887-175241967 0.00029 25_[+1]_47 chr6:39653125-39653205 0.00029 59_[+1]_13 chr15:58330348-58330428 0.00029 20_[+1]_52 chr11:20499098-20499178 0.00029 62_[+1]_10 chr12:8059828-8059908 0.00029 53_[+1]_19 chr20:46234651-46234731 0.00029 51_[+1]_21 chr6:84144350-84144430 0.00029 23_[+1]_49 chr15:66059429-66059509 0.00029 36_[+1]_36 chr6:43672683-43672763 0.00029 47_[+1]_25 chr4:147257768-147257848 0.00029 51_[+1]_21 chr6:159269616-159269696 0.00029 69_[+1]_3 chr2:205935791-205935871 0.00035 71_[+1]_1 chr12:9787817-9787897 0.00035 34_[+1]_38 chr7:24944693-24944773 0.00035 31_[+1]_41 chr8:59425949-59426029 0.00048 21_[+1]_51 chr8:126676795-126676875 0.00048 60_[+1]_12 chr19:33488142-33488222 0.00048 26_[+1]_46 chr10:126635628-12663570 0.00053 41_[+1]_31 chr21:22229401-22229481 0.00053 18_[+1]_54 chr7:150462899-150462979 0.00053 38_[+1]_34 chr1:28306226-28306306 0.00061 48_[+1]_24 chr13:50819360-50819440 0.00061 59_[+1]_13 chr5:162806746-162806826 0.00061 11_[+1]_61 chr16:75121338-75121418 0.00061 50_[+1]_22 chr6:71100039-71100119 0.00061 37_[+1]_35 chr17:75118042-75118122 0.00061 20_[+1]_52 chr1:154159364-154159444 0.00061 17_[+1]_55 chr8:94678601-94678681 0.00061 66_[+1]_6 chr9:128300465-128300545 0.00061 27_[+1]_45 chr8:5997544-5997624 0.00061 72_[+1] chr8:146180149-146180229 0.00061 42_[+1]_30 chr10:80218911-80218991 0.00068 21_[+1]_51 chr17:44836152-44836232 0.00068 14_[+1]_58 chr1:229645464-229645544 0.00068 6_[+1]_66 chr3:99650062-99650142 0.00068 72_[+1] chr12:47710416-47710496 0.00075 33_[+1]_39 chr8:129541424-129541504 0.00075 33_[+1]_39 chr10:62042786-62042866 0.00084 61_[+1]_11 chr17:19423140-19423220 0.00084 46_[+1]_26 chr15:82555863-82555943 0.00084 38_[+1]_34 chr4:80769644-80769724 0.00084 49_[+1]_23 chr10:127702285-12770236 0.00091 19_[+1]_53 chr4:77129656-77129736 0.001 47_[+1]_25 chr18:32509338-32509418 0.001 27_[+1]_45 chr9:110267258-110267338 0.001 19_[+1]_53 chr19:49078151-49078231 0.0011 16_[+1]_56 chr8:142238704-142238784 0.0011 27_[+1]_45 chr11:93811185-93811265 0.0011 7_[+1]_65 chr7:95932586-95932666 0.0011 9_[+1]_63 chr2:157559227-157559307 0.0011 34_[+1]_38 chr10:11645054-11645134 0.0012 1_[+1]_71 chr13:91129349-91129429 0.0013 64_[+1]_8 chr2:114367618-114367698 0.0014 27_[+1]_45 chr2:209503013-209503093 0.0014 7_[+1]_65 chr19:252947-253027 0.0014 4_[+1]_68 chr8:27316859-27316939 0.0014 62_[+1]_10 chr1:142876537-142876617 0.0017 11_[+1]_61 chr2:192502665-192502745 0.0017 66_[+1]_6 chr4:38874421-38874501 0.0017 42_[+1]_30 chr10:45857960-45858040 0.0017 28_[+1]_44 chr3:17462341-17462421 0.0017 58_[+1]_14 chr1:175703049-175703129 0.002 15_[+1]_57 chr5:82561157-82561237 0.0025 15_[+1]_57 chr7:72772511-72772591 0.0033 31_[+1]_41 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGTTTACW MEME-1 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF TGTTTACW width=8 seqs=158 chr3:88124801-88124881 ( 58) TGTTTACA 1 chr3:69882776-69882856 ( 63) TGTTTACA 1 chr10:76951966-76952046 ( 49) TGTTTACA 1 chr6:158246628-158246708 ( 49) TGTTTACA 1 chr5:81254097-81254177 ( 53) TGTTTACA 1 chr7:29762825-29762905 ( 37) TGTTTACA 1 chr5:65131196-65131276 ( 16) TGTTTACA 1 chr2:54799570-54799650 ( 1) TGTTTACA 1 chr10:35331939-35332019 ( 23) TGTTTACA 1 chr12:65050354-65050434 ( 62) TGTTTACA 1 chr7:22748040-22748120 ( 3) TGTTTACA 1 chr9:128046980-128047060 ( 13) TGTTTACA 1 chr18:33429406-33429486 ( 44) TGTTTACA 1 chr6:147513559-147513639 ( 33) TGTTTACA 1 chr17:77810008-77810088 ( 36) TGTTTACA 1 chr12:116966993-11696707 ( 62) TGTTTACA 1 chr19:29049854-29049934 ( 23) TGTTTACA 1 chr14:60766857-60766937 ( 73) TGTTTACA 1 chr5:180313046-180313126 ( 44) TGTTTACA 1 chr1:22740827-22740907 ( 7) TGTTTACA 1 chr10:112186082-11218616 ( 31) TGTTTACA 1 chr14:25451991-25452071 ( 18) TGTTTACA 1 chr11:5642584-5642664 ( 64) TGTTTACA 1 chr10:61833343-61833423 ( 56) TGTTTACT 1 chr7:137729787-137729867 ( 15) TGTTTACT 1 chr5:10507768-10507848 ( 25) TGTTTACT 1 chr1:26216949-26217029 ( 22) TGTTTACT 1 chr9:71123521-71123601 ( 23) TGTTTACT 1 chr11:59554593-59554673 ( 22) TGTTTACT 1 chr1:116963159-116963239 ( 58) TGTTTACT 1 chr2:205348340-205348420 ( 60) TGTTTACT 1 chr7:36636999-36637079 ( 26) TGTTTACT 1 chr17:61117829-61117909 ( 33) TGTTTACT 1 chr2:176800127-176800207 ( 55) TGTTTACT 1 chr3:152944743-152944823 ( 4) TGTTTACT 1 chr6:36991269-36991349 ( 46) TGTTTACT 1 chr5:126219638-126219718 ( 35) TGTTTACT 1 chr1:8121485-8121565 ( 34) TGTTTACT 1 chr6:126063718-126063798 ( 21) TGTTTACT 1 chr6:106525847-106525927 ( 7) TGTTTACT 1 chr16:33407385-33407465 ( 22) TGTTTACT 1 chr13:99628305-99628385 ( 28) TGTTTACC 1 chr10:121593798-12159387 ( 66) TGTGTACA 1 chr15:49144330-49144410 ( 63) TGTGTACA 1 chr8:99803241-99803321 ( 41) TGTTTACC 1 chr2:47306221-47306301 ( 42) TGTTTACC 1 chr5:131636379-131636459 ( 62) TGTTTACC 1 chr1:198638384-198638464 ( 2) TGTTTACC 1 chr12:12551416-12551496 ( 6) TGTTTACC 1 chr11:20111811-20111891 ( 31) TGTGTACA 1 chr2:171202275-171202355 ( 57) TGTGTACA 1 chr4:174529846-174529926 ( 43) TGTTTACC 1 chr3:183048845-183048925 ( 57) TGTTTACC 1 chr12:21504049-21504129 ( 5) TGTGTACA 1 chrX:150017600-150017680 ( 38) TGTGTACA 1 chr2:36739524-36739604 ( 19) TGTGTACA 1 chr5:130648166-130648246 ( 19) TGTTTACC 1 chr3:141422384-141422464 ( 42) TGTTTACC 1 chr4:83806729-83806809 ( 19) TGTTTACC 1 chr8:15559453-15559533 ( 23) TGTTGACA 1 chr5:180096385-180096465 ( 44) TGTTGACA 1 chr1:174842021-174842101 ( 39) TGTTTGCA 1 chr10:115626947-11562702 ( 43) TGTTTGCA 1 chr17:56465359-56465439 ( 23) TGTTGACA 1 chr6:161223124-161223204 ( 45) TGTTGACA 1 chr1:144881510-144881590 ( 12) TGTTTGCA 1 chr2:149259238-149259318 ( 41) TGTTGACA 1 chr13:24230994-24231074 ( 13) TGTTTGCA 1 chr11:13950556-13950636 ( 12) TGTTGACA 1 chr18:20681905-20681985 ( 16) TGTTGACA 1 chr3:58457217-58457297 ( 39) TGTTTGCA 1 chr2:223743155-223743235 ( 17) TGTTGACA 1 chr5:34246200-34246280 ( 27) TGTTGACA 1 chr1:246276893-246276973 ( 69) TATTTACA 1 chr1:54422549-54422629 ( 50) TATTTACA 1 chr2:179058357-179058437 ( 48) TATTTACA 1 chr6:133285443-133285523 ( 20) TATTTACA 1 chr21:43823050-43823130 ( 31) TATTTACA 1 chr4:111028270-111028350 ( 41) TATTTACA 1 chr6:20086193-20086273 ( 43) TATTTACA 1 chr12:50635160-50635240 ( 32) TATTTACA 1 chr1:157337842-157337922 ( 5) TATTTACA 1 chr14:69616726-69616806 ( 43) TGTGTACT 1 chr10:14223357-14223437 ( 25) TGTTTGCT 1 chr5:10494745-10494825 ( 41) TGTTGACT 1 chr11:65138806-65138886 ( 69) TGTTTGCT 1 chr3:142034872-142034952 ( 15) TGTTTAAA 1 chr17:73068150-73068230 ( 45) TGTTGACT 1 chr16:24998323-24998403 ( 21) TGTTTGCT 1 chr14:88490840-88490920 ( 7) TGTTGACT 1 chr6:90813344-90813424 ( 21) TGTTTGCT 1 chr5:132385459-132385539 ( 22) TGTTTGCT 1 chr1:47187632-47187712 ( 27) TGTTTGCT 1 chr5:123935496-123935576 ( 43) TGTTTAAA 1 chr4:175241887-175241967 ( 26) TATTTACT 1 chr6:39653125-39653205 ( 60) TATTTACT 1 chr15:58330348-58330428 ( 21) TATTTACT 1 chr11:20499098-20499178 ( 63) TATTTACT 1 chr12:8059828-8059908 ( 54) TATTTACT 1 chr20:46234651-46234731 ( 52) TATTTACT 1 chr6:84144350-84144430 ( 24) TATTTACT 1 chr15:66059429-66059509 ( 37) TATTTACT 1 chr6:43672683-43672763 ( 48) TATTTACT 1 chr4:147257768-147257848 ( 52) TATTTACT 1 chr6:159269616-159269696 ( 70) TATTTACT 1 chr2:205935791-205935871 ( 72) TGTGTGCA 1 chr12:9787817-9787897 ( 35) TGTTGACC 1 chr7:24944693-24944773 ( 32) TGTGGACA 1 chr8:59425949-59426029 ( 22) TATGTACA 1 chr8:126676795-126676875 ( 61) TATTTACC 1 chr19:33488142-33488222 ( 27) TATTTACC 1 chr10:126635628-12663570 ( 42) TATTGACA 1 chr21:22229401-22229481 ( 19) TATTTGCA 1 chr7:150462899-150462979 ( 39) TATTGACA 1 chr1:28306226-28306306 ( 49) TGTGTAAA 1 chr13:50819360-50819440 ( 60) TGTGTAAA 1 chr5:162806746-162806826 ( 12) TGTGTAAA 1 chr16:75121338-75121418 ( 51) TGTGTAAA 1 chr6:71100039-71100119 ( 38) TGTTTAAC 1 chr17:75118042-75118122 ( 21) TGTGTAAA 1 chr1:154159364-154159444 ( 18) TGTGTAAA 1 chr8:94678601-94678681 ( 67) TGTGTAAA 1 chr9:128300465-128300545 ( 28) TGTGTAAA 1 chr8:5997544-5997624 ( 73) TGTGTAAA 1 chr8:146180149-146180229 ( 43) TGTGTAAA 1 chr10:80218911-80218991 ( 22) TGTTTGAA 1 chr17:44836152-44836232 ( 15) TGTTGAAA 1 chr1:229645464-229645544 ( 7) TGTTGAAA 1 chr3:99650062-99650142 ( 73) TGTTTGAA 1 chr12:47710416-47710496 ( 34) TGTTTCCA 1 chr8:129541424-129541504 ( 34) TGTTTCCA 1 chr10:62042786-62042866 ( 62) TATTTGCT 1 chr17:19423140-19423220 ( 47) TATTGACT 1 chr15:82555863-82555943 ( 39) TATTTGCT 1 chr4:80769644-80769724 ( 50) TATTGACT 1 chr10:127702285-12770236 ( 20) TGTGGGCA 1 chr4:77129656-77129736 ( 48) TGAGTACA 1 chr18:32509338-32509418 ( 28) TGTTGAAT 1 chr9:110267258-110267338 ( 20) TGTTGAAT 1 chr19:49078151-49078231 ( 17) TGATGACA 1 chr8:142238704-142238784 ( 28) TGATGACA 1 chr11:93811185-93811265 ( 8) TGTTTCCT 1 chr7:95932586-95932666 ( 10) TATTTGCC 1 chr2:157559227-157559307 ( 35) TGATGACA 1 chr10:11645054-11645134 ( 2) TGTTTACG 1 chr13:91129349-91129429 ( 65) TAATTACA 1 chr2:114367618-114367698 ( 28) TGTTTGAC 1 chr2:209503013-209503093 ( 8) TGTGTGAA 1 chr19:252947-253027 ( 5) TGTTTGAC 1 chr8:27316859-27316939 ( 63) TGTTTGAC 1 chr1:142876537-142876617 ( 12) TGATTGCT 1 chr2:192502665-192502745 ( 67) TGATTAAA 1 chr4:38874421-38874501 ( 43) TATGTAAA 1 chr10:45857960-45858040 ( 29) TGATTGCT 1 chr3:17462341-17462421 ( 59) TATGTAAA 1 chr1:175703049-175703129 ( 16) TGAGGACA 1 chr5:82561157-82561237 ( 16) TGTTTATC 1 chr7:72772511-72772591 ( 32) TGTGTATT 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGTTTACW MEME-1 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 7.07889 E= 1.3e-089 -1395 -1395 -1395 180 -43 -1395 187 -1395 -234 -1395 -1395 172 -1395 -1395 -28 152 -1395 -1395 -33 153 151 -346 -44 -1395 -81 198 -1395 -450 95 -72 -509 11 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGTTTACW MEME-1 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 158 E= 1.3e-089 0.000000 0.000000 0.000000 1.000000 0.215190 0.000000 0.784810 0.000000 0.056962 0.000000 0.000000 0.943038 0.000000 0.000000 0.177215 0.822785 0.000000 0.000000 0.170886 0.829114 0.822785 0.018987 0.158228 0.000000 0.164557 0.822785 0.000000 0.012658 0.556962 0.126582 0.006329 0.310127 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGTTTACW MEME-1 regular expression -------------------------------------------------------------------------------- T[GA]TTTAC[AT] -------------------------------------------------------------------------------- Time 4.88 secs. ******************************************************************************** ******************************************************************************** MOTIF WGTAAACA MEME-2 width = 8 sites = 111 llr = 860 E-value = 1.2e-071 ******************************************************************************** -------------------------------------------------------------------------------- Motif WGTAAACA MEME-2 Description -------------------------------------------------------------------------------- Simplified A 61:8aa:a pos.-specific C ::22::7: probability G 19:::::: matrix T 3:8:::3: bits 2.3 2.0 1.8 ** * 1.6 * ** * Relative 1.4 * **** Entropy 1.1 ******* (11.2 bits) 0.9 ******* 0.7 ******* 0.5 ******** 0.2 ******** 0.0 -------- Multilevel AGTAAACA consensus T C T sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif WGTAAACA MEME-2 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr6:42535126-42535206 53 2.59e-05 CGGTTTTAAA AGTAAACA Tgccgggtgt chr21:44427046-44427126 41 2.59e-05 TAAGGCTTTA AGTAAACA CAGCTGGCCT chr8:66629754-66629834 49 2.59e-05 GCTCGGACTG AGTAAACA TCTGAGGGAT chr10:123822872-12382295 43 2.59e-05 TTTGGCAGGA AGTAAACA CAGAAAGGAG chr8:59425949-59426029 51 2.59e-05 TCTGTAGTTA AGTAAACA TGAGGAGGCA chr4:77129656-77129736 67 2.59e-05 AGCCAGGCTG AGTAAACA GAGGAA chr1:246445119-246445199 15 2.59e-05 CCAAGACATA AGTAAACA GAATGCTATG chr15:91056911-91056991 65 2.59e-05 ggaccacatg agtaaaca agctagtt chr5:82561157-82561237 35 2.59e-05 TAGTTGCAAA AGTAAACA TGGTGGTGGT chr20:30913768-30913848 25 2.59e-05 ATATCTTTTG AGTAAACA GTGAGTCAGC chr1:15954591-15954671 44 2.59e-05 TGGTCTATTA AGTAAACA TGTTTTTGAG chr16:3696424-3696504 8 2.59e-05 GTGCCTG AGTAAACA CACCAGAGCA chr1:65784148-65784228 28 2.59e-05 GATGTACCTG AGTAAACA CAGATTCCCt chr12:47710416-47710496 17 2.59e-05 TCCTCCTTAA AGTAAACA GCACACAGCT chr8:86957068-86957148 26 2.59e-05 CATGGCACTG AGTAAACA GGAAAAGAGA chr11:20499098-20499178 23 2.59e-05 aGAGTTGAAG AGTAAACA GCATAGTGAG chr11:46872560-46872640 21 2.59e-05 aaaggttttg agtaaaca ctgctagagg chr2:157559227-157559307 67 2.59e-05 TCAGTAACTG AGTAAACA CACATA chr8:94678601-94678681 56 2.59e-05 TATCACAGTG AGTAAACA TTCTGTGTAA chr8:102904131-102904211 64 2.59e-05 ggcttgctta agtaaaca aagcagcca chr19:33488142-33488222 66 2.59e-05 taaagcaacg agtaaaca aactgcc chr10:62185283-62185363 60 2.59e-05 CCCTTCCTTA AGTAAACA ACCAACCCTG chr16:31111702-31111782 25 2.59e-05 cataggccaa agtaaaca tccagagtga chr11:74770503-74770583 57 2.59e-05 caccagcttg agtaaaca caaaattcat chr6:134519312-134519392 55 2.59e-05 TTATGACCTG AGTAAACA AGGTTAGTCA chr1:229645464-229645544 29 2.59e-05 ggaatGGTTA AGTAAACA TTGACGTATT chr4:77890825-77890905 31 2.59e-05 ATCACAGCTG AGTAAACA CAACCAAGGA chr1:150450470-150450550 26 2.59e-05 TTGGCCCTTA AGTAAACA TCCTGTTCTG chr4:113034368-113034448 37 5.16e-05 gtcatgataa tgtaaaca ctgagtattg chr8:8917253-8917333 57 5.16e-05 gaaccggcag tgtaaaca agagcagggc chr12:104198858-10419893 25 5.16e-05 tgagtcataa tgtaaaca gtgaccagta chr2:192502665-192502745 45 5.16e-05 aatatttctt tgtaaaca aggaaaagct chr9:125293604-125293684 51 5.16e-05 aaactggcag tgtaaaca agagcagggc chr11:60138379-60138459 1 5.16e-05 . TGTAAACA ATGACTCACT chr6:90813344-90813424 47 5.16e-05 TACTTCCTTG TGTAAACA GGTTGTCTCA chr2:106806681-106806761 27 5.16e-05 tagtcatgct tgtaaaca ctgcatgatg chr14:23265732-23265812 54 5.16e-05 AACAGTACTC TGTAAACA AAGAGCCCTG chr4:134185558-134185638 36 5.16e-05 ggagaaacag tgtaaaca ggcagtgtaa chr11:5642584-5642664 13 5.16e-05 TCTCTGCCTG TGTAAACA AGCCTTGAGG chr8:142238704-142238784 14 7.03e-05 TGTTGCAACA AGCAAACA TCTTTGTGAT chr1:167713036-167713116 48 7.03e-05 tcttatcatc agcaaaca acaacagttt chr10:126635628-12663570 34 7.03e-05 AGCAGTATCG AGCAAACA TATTGACATA chr3:138405760-138405840 65 7.03e-05 AACTGGGCTA AGCAAACA GGAACTTT chr20:22384669-22384749 39 7.03e-05 GTTCAACATA AGCAAACA GATTGTAAAC chr3:99650062-99650142 6 7.03e-05 TTTAA AGCAAACA TTTAAAAAAA chr14:69616726-69616806 11 7.03e-05 CCTTATCTGA AGCAAACA GGAGGAACTT chr7:2551215-2551295 66 7.03e-05 ACCCCGGCTG AGCAAACA GCTTTCC chr6:97079305-97079385 34 8.89e-05 ATAAACGTTG AGTCAACA AAGCAGACAG chrX:119683983-119684063 33 8.89e-05 TTAGTCATTG AGTCAACA CTATTTATCT chr19:20344158-20344238 58 8.89e-05 cctcagtctg agtcaaca tacaacccca chr5:19099488-19099568 47 8.89e-05 ctcaacatca agtcaaca gcctccacca chr9:90400665-90400745 11 8.89e-05 ttaaacctta agtcaaca cagcacatgt chr7:72772511-72772591 8 8.89e-05 GTCCCTG AGTCAACA CCAATAGAGA chr3:141013755-141013835 52 8.89e-05 TGTGGCTAAG AGTCAACA CCAAAAGTGT chr3:186324203-186324283 56 8.89e-05 TCATTGCTAA AGTCAACA AGTCAAAGTG chr8:129356346-129356426 10 1.08e-04 gcttgctta ggtaaaca aagcagcctg chrX:46907612-46907692 22 1.08e-04 aaggacccaa ggtaaaca aagacactct chr5:74991932-74992012 60 1.08e-04 ggcttgctta ggtaaaca aagcagcccg chr6:84144350-84144430 35 1.08e-04 ATTTACTCTG GGTAAACA CTATACCACA chr4:113021007-113021087 43 1.08e-04 AAATAATAAA GGTAAACA AAGCCAATAA chr3:33109112-33109192 8 1.44e-04 TATGCTA AGTAAATA GGAAGAGAAA chr15:58025104-58025184 54 1.44e-04 AAACCGCCAA AGTAAATA CCCTCCTGTG chr12:30916188-30916268 59 1.44e-04 ACAGGACAAA AGTAAATA TGGTTTACCA chr12:21504049-21504129 34 1.44e-04 GGAGGCACTG AGTAAATA AGAAGTTAGC chr15:82555863-82555943 48 1.44e-04 TTATTTGCTA AGTAAATA TGAACGTTGT chr1:101602358-101602438 7 1.44e-04 CTCCAA AGTAAATA AAGCATGAAA chr12:50635160-50635240 53 1.44e-04 TGGTTAGTTG AGTAAATA AGCTCAGAGG chr6:36991269-36991349 55 1.63e-04 CTGTTTACTC TGCAAACA GAGAAGCCCT chr1:8121485-8121565 21 1.63e-04 GAGATGGATG TGCAAACA TGAAGTGTTT chr2:209503013-209503093 68 1.63e-04 accccagtac TGCAAACA GAGTG chr21:22229401-22229481 35 1.63e-04 CACAGTACTC TGCAAACA TCACGATCCC chr6:136928424-136928504 48 1.81e-04 ATTCAAGTAA TGTCAACA ACAAATTATG chr6:161971465-161971545 21 1.81e-04 gagaagctta tgtcaaca tctatgacgt chr8:131277003-131277083 38 1.81e-04 TAAACCACAA TGTCAACA CACGATGATC chr1:75155679-75155759 32 1.81e-04 AAGTGCATTG TGTCAACA ACAGCAAAAG chr7:137729787-137729867 52 2.16e-04 tattccattg tgtaaata tactacaagt chr3:142034872-142034952 60 2.16e-04 tatgtggcta tgtaaata ttatcactgc chr5:148039385-148039465 8 2.16e-04 ctcactc tgtaaata acttattgat chr18:32509338-32509418 18 2.16e-04 ATTAGGGCTT TGTAAATA TTTGTTGAAT chr6:20086193-20086273 62 2.16e-04 aagaacacaa tgtaaata ttgaatctta chr5:34246200-34246280 72 2.16e-04 AATTAAGCTG TGTAAATA T chr12:116966993-11696707 26 2.44e-04 TTAATGGCTT GGCAAACA CAAGGATCAT chr1:206554430-206554510 29 3.18e-04 AGCCTGTTCA AATAAACA GGGATAATAG chr12:9787817-9787897 12 3.18e-04 tgtgccagtt agcaaata cagatggcct chr2:54799570-54799650 65 3.18e-04 TCACACTCTG AGCAAATA GAGGCTGG chr16:24998323-24998403 70 3.18e-04 ACAAGACCTA AATAAACA CAG chr4:95394187-95394267 39 3.18e-04 gtagaaggtg agcaaata agacctcaca chr10:112186082-11218616 50 3.18e-04 agtcagaaaa ggtcaaca cagaatagcg chr1:180784517-180784597 18 3.84e-04 GTAGGGGGAG GGTAAATA TAGTTAAAGC chr12:120099823-12009990 35 3.84e-04 ggcttgcata ggtaaata ccagcagctg chr6:43672683-43672763 9 3.84e-04 CTTTCTTT GGTAAATA TGCCATTCAC chr12:31430183-31430263 17 3.84e-04 ggagaggctg ggtaaata agataaaggc chr16:33407385-33407465 61 3.84e-04 cagcacattt ggtaaata tttgttgagt chr8:103343491-103343571 46 4.44e-04 cagagcccag tgcaaata agcactcaat chr15:66059429-66059509 12 4.44e-04 GCATAGCAGT TATAAACA CATGGTAGGT chr17:44836152-44836232 35 4.44e-04 GTGAGTCAGC TATAAACA AACACCCCAG chr3:41309628-41309708 49 4.70e-04 tgactcacaa tgtcaata gtgccgaggt chr10:62042786-62042866 5 4.70e-04 attg tgtcaata tctggataca chr8:42400413-42400493 65 4.70e-04 GTCACAGCTG TGTCAATA GCAAAATG chr6:119451239-119451319 43 4.70e-04 TATTTTTCCA TGTCAATA TTTGGAATAT chr12:8059828-8059908 32 4.70e-04 TATCTCATTA TGTCAATA AAAGTGACTC chr9:110267258-110267338 49 4.70e-04 AGCCTCTCTG TGTCAATA GACAGAGTCA chr19:49078151-49078231 31 5.05e-04 GACATCACTG AACAaaca aagtaactgc chr3:34053751-34053831 13 5.05e-04 TCACTGTCCA AACAAACA CCCCAAATTC chr7:12991278-12991358 50 5.05e-04 GAGTCATTTA AACAAACA AAGCTTCAGT chr6:7591211-7591291 4 5.05e-04 aaa aacaaaca aacaaaaTCC chr3:17462341-17462421 69 5.05e-04 TATGTAAATA AACAAACA TGAA chr5:123935496-123935576 25 5.05e-04 CATTCTCTTA AACAAACA CAGACTTCCT chr10:11645054-11645134 20 5.49e-04 CTATTCACTA AATCAACA AAGTACTTCC chr5:132385459-132385539 47 5.94e-04 TAACAACTGA GATAAACA GATGGAGACA chrX:150017600-150017680 9 7.29e-04 GTGGCCTC TATCAACA ATCACACTCA -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif WGTAAACA MEME-2 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr6:42535126-42535206 2.6e-05 52_[+2]_20 chr21:44427046-44427126 2.6e-05 40_[+2]_32 chr8:66629754-66629834 2.6e-05 48_[+2]_24 chr10:123822872-12382295 2.6e-05 42_[+2]_30 chr8:59425949-59426029 2.6e-05 50_[+2]_22 chr4:77129656-77129736 2.6e-05 66_[+2]_6 chr1:246445119-246445199 2.6e-05 14_[+2]_58 chr15:91056911-91056991 2.6e-05 64_[+2]_8 chr5:82561157-82561237 2.6e-05 34_[+2]_38 chr20:30913768-30913848 2.6e-05 24_[+2]_48 chr1:15954591-15954671 2.6e-05 43_[+2]_29 chr16:3696424-3696504 2.6e-05 7_[+2]_65 chr1:65784148-65784228 2.6e-05 27_[+2]_45 chr12:47710416-47710496 2.6e-05 16_[+2]_56 chr8:86957068-86957148 2.6e-05 25_[+2]_47 chr11:20499098-20499178 2.6e-05 22_[+2]_50 chr11:46872560-46872640 2.6e-05 20_[+2]_52 chr2:157559227-157559307 2.6e-05 66_[+2]_6 chr8:94678601-94678681 2.6e-05 55_[+2]_17 chr8:102904131-102904211 2.6e-05 63_[+2]_9 chr19:33488142-33488222 2.6e-05 65_[+2]_7 chr10:62185283-62185363 2.6e-05 59_[+2]_13 chr16:31111702-31111782 2.6e-05 24_[+2]_48 chr11:74770503-74770583 2.6e-05 56_[+2]_16 chr6:134519312-134519392 2.6e-05 54_[+2]_18 chr1:229645464-229645544 2.6e-05 28_[+2]_44 chr4:77890825-77890905 2.6e-05 30_[+2]_42 chr1:150450470-150450550 2.6e-05 25_[+2]_47 chr4:113034368-113034448 5.2e-05 36_[+2]_36 chr8:8917253-8917333 5.2e-05 56_[+2]_16 chr12:104198858-10419893 5.2e-05 24_[+2]_48 chr2:192502665-192502745 5.2e-05 44_[+2]_28 chr9:125293604-125293684 5.2e-05 50_[+2]_22 chr11:60138379-60138459 5.2e-05 [+2]_72 chr6:90813344-90813424 5.2e-05 46_[+2]_26 chr2:106806681-106806761 5.2e-05 26_[+2]_46 chr14:23265732-23265812 5.2e-05 53_[+2]_19 chr4:134185558-134185638 5.2e-05 35_[+2]_37 chr11:5642584-5642664 5.2e-05 12_[+2]_60 chr8:142238704-142238784 7e-05 13_[+2]_59 chr1:167713036-167713116 7e-05 47_[+2]_25 chr10:126635628-12663570 7e-05 33_[+2]_39 chr3:138405760-138405840 7e-05 64_[+2]_8 chr20:22384669-22384749 7e-05 38_[+2]_34 chr3:99650062-99650142 7e-05 5_[+2]_67 chr14:69616726-69616806 7e-05 10_[+2]_62 chr7:2551215-2551295 7e-05 65_[+2]_7 chr6:97079305-97079385 8.9e-05 33_[+2]_39 chrX:119683983-119684063 8.9e-05 32_[+2]_40 chr19:20344158-20344238 8.9e-05 57_[+2]_15 chr5:19099488-19099568 8.9e-05 46_[+2]_26 chr9:90400665-90400745 8.9e-05 10_[+2]_62 chr7:72772511-72772591 8.9e-05 7_[+2]_65 chr3:141013755-141013835 8.9e-05 51_[+2]_21 chr3:186324203-186324283 8.9e-05 55_[+2]_17 chr8:129356346-129356426 0.00011 9_[+2]_63 chrX:46907612-46907692 0.00011 21_[+2]_51 chr5:74991932-74992012 0.00011 59_[+2]_13 chr6:84144350-84144430 0.00011 34_[+2]_38 chr4:113021007-113021087 0.00011 42_[+2]_30 chr3:33109112-33109192 0.00014 7_[+2]_65 chr15:58025104-58025184 0.00014 53_[+2]_19 chr12:30916188-30916268 0.00014 58_[+2]_14 chr12:21504049-21504129 0.00014 33_[+2]_39 chr15:82555863-82555943 0.00014 47_[+2]_25 chr1:101602358-101602438 0.00014 6_[+2]_66 chr12:50635160-50635240 0.00014 52_[+2]_20 chr6:36991269-36991349 0.00016 54_[+2]_18 chr1:8121485-8121565 0.00016 20_[+2]_52 chr2:209503013-209503093 0.00016 67_[+2]_5 chr21:22229401-22229481 0.00016 34_[+2]_38 chr6:136928424-136928504 0.00018 47_[+2]_25 chr6:161971465-161971545 0.00018 20_[+2]_52 chr8:131277003-131277083 0.00018 37_[+2]_35 chr1:75155679-75155759 0.00018 31_[+2]_41 chr7:137729787-137729867 0.00022 51_[+2]_21 chr3:142034872-142034952 0.00022 59_[+2]_13 chr5:148039385-148039465 0.00022 7_[+2]_65 chr18:32509338-32509418 0.00022 17_[+2]_55 chr6:20086193-20086273 0.00022 61_[+2]_11 chr5:34246200-34246280 0.00022 71_[+2]_1 chr12:116966993-11696707 0.00024 25_[+2]_47 chr1:206554430-206554510 0.00032 28_[+2]_44 chr12:9787817-9787897 0.00032 11_[+2]_61 chr2:54799570-54799650 0.00032 64_[+2]_8 chr16:24998323-24998403 0.00032 69_[+2]_3 chr4:95394187-95394267 0.00032 38_[+2]_34 chr10:112186082-11218616 0.00032 49_[+2]_23 chr1:180784517-180784597 0.00038 17_[+2]_55 chr12:120099823-12009990 0.00038 34_[+2]_38 chr6:43672683-43672763 0.00038 8_[+2]_64 chr12:31430183-31430263 0.00038 16_[+2]_56 chr16:33407385-33407465 0.00038 60_[+2]_12 chr8:103343491-103343571 0.00044 45_[+2]_27 chr15:66059429-66059509 0.00044 11_[+2]_61 chr17:44836152-44836232 0.00044 34_[+2]_38 chr3:41309628-41309708 0.00047 48_[+2]_24 chr10:62042786-62042866 0.00047 4_[+2]_68 chr8:42400413-42400493 0.00047 64_[+2]_8 chr6:119451239-119451319 0.00047 42_[+2]_30 chr12:8059828-8059908 0.00047 31_[+2]_41 chr9:110267258-110267338 0.00047 48_[+2]_24 chr19:49078151-49078231 0.00051 30_[+2]_42 chr3:34053751-34053831 0.00051 12_[+2]_60 chr7:12991278-12991358 0.00051 49_[+2]_23 chr6:7591211-7591291 0.00051 3_[+2]_69 chr3:17462341-17462421 0.00051 68_[+2]_4 chr5:123935496-123935576 0.00051 24_[+2]_48 chr10:11645054-11645134 0.00055 19_[+2]_53 chr5:132385459-132385539 0.00059 46_[+2]_26 chrX:150017600-150017680 0.00073 8_[+2]_64 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif WGTAAACA MEME-2 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF WGTAAACA width=8 seqs=111 chr6:42535126-42535206 ( 53) AGTAAACA 1 chr21:44427046-44427126 ( 41) AGTAAACA 1 chr8:66629754-66629834 ( 49) AGTAAACA 1 chr10:123822872-12382295 ( 43) AGTAAACA 1 chr8:59425949-59426029 ( 51) AGTAAACA 1 chr4:77129656-77129736 ( 67) AGTAAACA 1 chr1:246445119-246445199 ( 15) AGTAAACA 1 chr15:91056911-91056991 ( 65) AGTAAACA 1 chr5:82561157-82561237 ( 35) AGTAAACA 1 chr20:30913768-30913848 ( 25) AGTAAACA 1 chr1:15954591-15954671 ( 44) AGTAAACA 1 chr16:3696424-3696504 ( 8) AGTAAACA 1 chr1:65784148-65784228 ( 28) AGTAAACA 1 chr12:47710416-47710496 ( 17) AGTAAACA 1 chr8:86957068-86957148 ( 26) AGTAAACA 1 chr11:20499098-20499178 ( 23) AGTAAACA 1 chr11:46872560-46872640 ( 21) AGTAAACA 1 chr2:157559227-157559307 ( 67) AGTAAACA 1 chr8:94678601-94678681 ( 56) AGTAAACA 1 chr8:102904131-102904211 ( 64) AGTAAACA 1 chr19:33488142-33488222 ( 66) AGTAAACA 1 chr10:62185283-62185363 ( 60) AGTAAACA 1 chr16:31111702-31111782 ( 25) AGTAAACA 1 chr11:74770503-74770583 ( 57) AGTAAACA 1 chr6:134519312-134519392 ( 55) AGTAAACA 1 chr1:229645464-229645544 ( 29) AGTAAACA 1 chr4:77890825-77890905 ( 31) AGTAAACA 1 chr1:150450470-150450550 ( 26) AGTAAACA 1 chr4:113034368-113034448 ( 37) TGTAAACA 1 chr8:8917253-8917333 ( 57) TGTAAACA 1 chr12:104198858-10419893 ( 25) TGTAAACA 1 chr2:192502665-192502745 ( 45) TGTAAACA 1 chr9:125293604-125293684 ( 51) TGTAAACA 1 chr11:60138379-60138459 ( 1) TGTAAACA 1 chr6:90813344-90813424 ( 47) TGTAAACA 1 chr2:106806681-106806761 ( 27) TGTAAACA 1 chr14:23265732-23265812 ( 54) TGTAAACA 1 chr4:134185558-134185638 ( 36) TGTAAACA 1 chr11:5642584-5642664 ( 13) TGTAAACA 1 chr8:142238704-142238784 ( 14) AGCAAACA 1 chr1:167713036-167713116 ( 48) AGCAAACA 1 chr10:126635628-12663570 ( 34) AGCAAACA 1 chr3:138405760-138405840 ( 65) AGCAAACA 1 chr20:22384669-22384749 ( 39) AGCAAACA 1 chr3:99650062-99650142 ( 6) AGCAAACA 1 chr14:69616726-69616806 ( 11) AGCAAACA 1 chr7:2551215-2551295 ( 66) AGCAAACA 1 chr6:97079305-97079385 ( 34) AGTCAACA 1 chrX:119683983-119684063 ( 33) AGTCAACA 1 chr19:20344158-20344238 ( 58) AGTCAACA 1 chr5:19099488-19099568 ( 47) AGTCAACA 1 chr9:90400665-90400745 ( 11) AGTCAACA 1 chr7:72772511-72772591 ( 8) AGTCAACA 1 chr3:141013755-141013835 ( 52) AGTCAACA 1 chr3:186324203-186324283 ( 56) AGTCAACA 1 chr8:129356346-129356426 ( 10) GGTAAACA 1 chrX:46907612-46907692 ( 22) GGTAAACA 1 chr5:74991932-74992012 ( 60) GGTAAACA 1 chr6:84144350-84144430 ( 35) GGTAAACA 1 chr4:113021007-113021087 ( 43) GGTAAACA 1 chr3:33109112-33109192 ( 8) AGTAAATA 1 chr15:58025104-58025184 ( 54) AGTAAATA 1 chr12:30916188-30916268 ( 59) AGTAAATA 1 chr12:21504049-21504129 ( 34) AGTAAATA 1 chr15:82555863-82555943 ( 48) AGTAAATA 1 chr1:101602358-101602438 ( 7) AGTAAATA 1 chr12:50635160-50635240 ( 53) AGTAAATA 1 chr6:36991269-36991349 ( 55) TGCAAACA 1 chr1:8121485-8121565 ( 21) TGCAAACA 1 chr2:209503013-209503093 ( 68) TGCAAACA 1 chr21:22229401-22229481 ( 35) TGCAAACA 1 chr6:136928424-136928504 ( 48) TGTCAACA 1 chr6:161971465-161971545 ( 21) TGTCAACA 1 chr8:131277003-131277083 ( 38) TGTCAACA 1 chr1:75155679-75155759 ( 32) TGTCAACA 1 chr7:137729787-137729867 ( 52) TGTAAATA 1 chr3:142034872-142034952 ( 60) TGTAAATA 1 chr5:148039385-148039465 ( 8) TGTAAATA 1 chr18:32509338-32509418 ( 18) TGTAAATA 1 chr6:20086193-20086273 ( 62) TGTAAATA 1 chr5:34246200-34246280 ( 72) TGTAAATA 1 chr12:116966993-11696707 ( 26) GGCAAACA 1 chr1:206554430-206554510 ( 29) AATAAACA 1 chr12:9787817-9787897 ( 12) AGCAAATA 1 chr2:54799570-54799650 ( 65) AGCAAATA 1 chr16:24998323-24998403 ( 70) AATAAACA 1 chr4:95394187-95394267 ( 39) AGCAAATA 1 chr10:112186082-11218616 ( 50) GGTCAACA 1 chr1:180784517-180784597 ( 18) GGTAAATA 1 chr12:120099823-12009990 ( 35) GGTAAATA 1 chr6:43672683-43672763 ( 9) GGTAAATA 1 chr12:31430183-31430263 ( 17) GGTAAATA 1 chr16:33407385-33407465 ( 61) GGTAAATA 1 chr8:103343491-103343571 ( 46) TGCAAATA 1 chr15:66059429-66059509 ( 12) TATAAACA 1 chr17:44836152-44836232 ( 35) TATAAACA 1 chr3:41309628-41309708 ( 49) TGTCAATA 1 chr10:62042786-62042866 ( 5) TGTCAATA 1 chr8:42400413-42400493 ( 65) TGTCAATA 1 chr6:119451239-119451319 ( 43) TGTCAATA 1 chr12:8059828-8059908 ( 32) TGTCAATA 1 chr9:110267258-110267338 ( 49) TGTCAATA 1 chr19:49078151-49078231 ( 31) AACAAACA 1 chr3:34053751-34053831 ( 13) AACAAACA 1 chr7:12991278-12991358 ( 50) AACAAACA 1 chr6:7591211-7591291 ( 4) AACAAACA 1 chr3:17462341-17462421 ( 69) AACAAACA 1 chr5:123935496-123935576 ( 25) AACAAACA 1 chr10:11645054-11645134 ( 20) AATCAACA 1 chr5:132385459-132385539 ( 47) GATAAACA 1 chrX:150017600-150017680 ( 9) TATCAACA 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif WGTAAACA MEME-2 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 8.57289 E= 1.2e-071 97 -1344 -88 14 -130 -1344 204 -1344 -1344 -1 -1344 147 149 -14 -1344 -1344 179 -1344 -1344 -1344 179 -1344 -1344 -1344 -1344 184 -1344 -19 179 -1344 -1344 -1344 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif WGTAAACA MEME-2 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 111 E= 1.2e-071 0.567568 0.000000 0.117117 0.315315 0.117117 0.000000 0.882883 0.000000 0.000000 0.207207 0.000000 0.792793 0.810811 0.189189 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.747748 0.000000 0.252252 1.000000 0.000000 0.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif WGTAAACA MEME-2 regular expression -------------------------------------------------------------------------------- [AT]G[TC]AAA[CT]A -------------------------------------------------------------------------------- Time 8.34 secs. ******************************************************************************** ******************************************************************************** MOTIF CAGCWGHS MEME-3 width = 8 sites = 42 llr = 342 E-value = 6.6e-006 ******************************************************************************** -------------------------------------------------------------------------------- Motif CAGCWGHS MEME-3 Description -------------------------------------------------------------------------------- Simplified A :9::4:22 pos.-specific C a::a::33 probability G :1a::a15 matrix T ::::6:4: bits 2.3 * ** * 2.0 * ** * 1.8 * ** * 1.6 * ** * Relative 1.4 **** * Entropy 1.1 **** * (11.7 bits) 0.9 ****** 0.7 ****** * 0.5 ****** * 0.2 ****** * 0.0 -------- Multilevel CAGCTGTG consensus A CC sequence AA -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CAGCWGHS MEME-3 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr8:8917253-8917333 19 7.42e-06 caggcgatat cagctgcg atggcttgga chr3:197159785-197159865 49 1.77e-05 tctgtttgtg cagctgtg acaaaatatc chr13:24230994-24231074 21 1.77e-05 AGTGTTTGCA CAGCTGTG CTTGTGCTCA chr9:125293604-125293684 13 1.77e-05 caggagatat cagctgtg atggtttgga chr2:114367618-114367698 36 1.77e-05 cgtgtttgac cagctgtg tgtgtctctc chr3:152944743-152944823 56 1.77e-05 caggagatat cagctgtg atggcttgga chr12:120099823-12009990 47 1.77e-05 taaataccag cagctgtg ccaatagaaa chr19:252947-253027 13 1.77e-05 cgtgtttgac cagctgtg tgtgtcctta chr4:134185558-134185638 11 1.77e-05 cagcagatat cagctgtg gtggcttgga chr8:146180149-146180229 7 1.77e-05 agatat cagctgtg atggcttgca chr1:142876537-142876617 50 2.51e-05 aactgcaagg cagcagcg aggctggggg chr7:24944693-24944773 6 3.54e-05 gcaaa cagcagtg gtgaaaacta chr2:152709922-152710002 63 5.29e-05 GCAAGTTTAT CAGCTGCC ACCAGTTGAA chr10:127702285-12770236 71 5.29e-05 GGAGTAACTG CAGCTGCC TA chr1:144881510-144881590 26 7.05e-05 TGCATTGTGA CAGCTGGG AGCGCAGGTG chr1:180784517-180784597 36 7.05e-05 TAGTTAAAGC CAGCTGTC TATCCTTATT chr2:209503013-209503093 30 7.05e-05 aatagtgagt cagctggg agtgtccaaa chr11:62316448-62316528 20 8.09e-05 AGGATCCAAA CAGCAGAG GCCAGAGTCC chr17:61117829-61117909 52 8.09e-05 AAGCCACACC CAGCAGAG TCAGCTTTTA chr11:60138379-60138459 31 8.09e-05 AGAATTTTGT CAGCAGAG TATTATTTGT chr1:206554430-206554510 15 8.81e-05 CAGATCACTT CAGCAGCC TGTTCAAATA chr17:75118042-75118122 43 8.81e-05 CATTAGTCAG CAGCAGCC CACACACTGG chr10:80218911-80218991 53 1.06e-04 TTTGTTTGTA CAGCAGTC CATGAAGTCA chr11:75460030-75460110 21 1.06e-04 attgctagca cagcagtc tgagatcaaa chr10:45857960-45858040 41 1.06e-04 attgctagca cagcagtc tgagatcaaa chr3:17462341-17462421 51 1.16e-04 ATCAGGCTTT CAGCTGAC TATGTAAATA chr21:44427046-44427126 49 1.47e-04 TAAGTAAACA CAGCTGGC CTTTTCCTTT chr5:19099488-19099568 29 1.72e-04 ccttatcagt cagcagca ctcaacatca chr10:126635628-12663570 23 2.01e-04 ACTAACACAT CAGCAGTA TCGAGCAAAC chr5:180096385-180096465 13 2.15e-04 AATCTAGAAA CAGCTGAA CAAACTGTAG chr2:234130541-234130621 52 2.15e-04 caagttgaca cagctgaa atgagccact chr5:74991932-74992012 11 2.21e-04 aactgcaagg cggcagcg aggctggggg chr15:79012566-79012646 26 2.21e-04 aactgcaagg cggcagcg aggctggggg chr8:102904131-102904211 15 2.21e-04 aactgcaagg cggcagcg aggctggggg chr4:77129656-77129736 6 2.39e-04 GTCAA CAGCTGGA AAGTCACACT chr16:75121338-75121418 6 2.39e-04 GGAAG CAGCTGGA CTCTGGCTGA chr8:103343491-103343571 14 2.39e-04 gttcaagggt cagctgga taaagtacac chr5:65131196-65131276 58 2.60e-04 aagcatctat cagcagaa gagtggataa chr4:175241887-175241967 46 2.60e-04 ACCAtttaag cagcagaa tatgataacc chr3:186324203-186324283 38 2.60e-04 ACTTTAAGAC CGGCTGAG TCATTGCTAA chr6:158246628-158246708 10 2.66e-04 AGTTTCTTT CGGCTGCC TAATCACTGT chr16:3696424-3696504 42 2.97e-04 TCATATGGGC CGGCAGAG ATGAACCTGG -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CAGCWGHS MEME-3 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr8:8917253-8917333 7.4e-06 18_[+3]_54 chr3:197159785-197159865 1.8e-05 48_[+3]_24 chr13:24230994-24231074 1.8e-05 20_[+3]_52 chr9:125293604-125293684 1.8e-05 12_[+3]_60 chr2:114367618-114367698 1.8e-05 35_[+3]_37 chr3:152944743-152944823 1.8e-05 55_[+3]_17 chr12:120099823-12009990 1.8e-05 46_[+3]_26 chr19:252947-253027 1.8e-05 12_[+3]_60 chr4:134185558-134185638 1.8e-05 10_[+3]_62 chr8:146180149-146180229 1.8e-05 6_[+3]_66 chr1:142876537-142876617 2.5e-05 49_[+3]_23 chr7:24944693-24944773 3.5e-05 5_[+3]_67 chr2:152709922-152710002 5.3e-05 62_[+3]_10 chr10:127702285-12770236 5.3e-05 70_[+3]_2 chr1:144881510-144881590 7e-05 25_[+3]_47 chr1:180784517-180784597 7e-05 35_[+3]_37 chr2:209503013-209503093 7e-05 29_[+3]_43 chr11:62316448-62316528 8.1e-05 19_[+3]_53 chr17:61117829-61117909 8.1e-05 51_[+3]_21 chr11:60138379-60138459 8.1e-05 30_[+3]_42 chr1:206554430-206554510 8.8e-05 14_[+3]_58 chr17:75118042-75118122 8.8e-05 42_[+3]_30 chr10:80218911-80218991 0.00011 52_[+3]_20 chr11:75460030-75460110 0.00011 20_[+3]_52 chr10:45857960-45858040 0.00011 40_[+3]_32 chr3:17462341-17462421 0.00012 50_[+3]_22 chr21:44427046-44427126 0.00015 48_[+3]_24 chr5:19099488-19099568 0.00017 28_[+3]_44 chr10:126635628-12663570 0.0002 22_[+3]_50 chr5:180096385-180096465 0.00022 12_[+3]_60 chr2:234130541-234130621 0.00022 51_[+3]_21 chr5:74991932-74992012 0.00022 10_[+3]_62 chr15:79012566-79012646 0.00022 25_[+3]_47 chr8:102904131-102904211 0.00022 14_[+3]_58 chr4:77129656-77129736 0.00024 5_[+3]_67 chr16:75121338-75121418 0.00024 5_[+3]_67 chr8:103343491-103343571 0.00024 13_[+3]_59 chr5:65131196-65131276 0.00026 57_[+3]_15 chr4:175241887-175241967 0.00026 45_[+3]_27 chr3:186324203-186324283 0.00026 37_[+3]_35 chr6:158246628-158246708 0.00027 9_[+3]_63 chr16:3696424-3696504 0.0003 41_[+3]_31 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CAGCWGHS MEME-3 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF CAGCWGHS width=8 seqs=42 chr8:8917253-8917333 ( 19) CAGCTGCG 1 chr3:197159785-197159865 ( 49) CAGCTGTG 1 chr13:24230994-24231074 ( 21) CAGCTGTG 1 chr9:125293604-125293684 ( 13) CAGCTGTG 1 chr2:114367618-114367698 ( 36) CAGCTGTG 1 chr3:152944743-152944823 ( 56) CAGCTGTG 1 chr12:120099823-12009990 ( 47) CAGCTGTG 1 chr19:252947-253027 ( 13) CAGCTGTG 1 chr4:134185558-134185638 ( 11) CAGCTGTG 1 chr8:146180149-146180229 ( 7) CAGCTGTG 1 chr1:142876537-142876617 ( 50) CAGCAGCG 1 chr7:24944693-24944773 ( 6) CAGCAGTG 1 chr2:152709922-152710002 ( 63) CAGCTGCC 1 chr10:127702285-12770236 ( 71) CAGCTGCC 1 chr1:144881510-144881590 ( 26) CAGCTGGG 1 chr1:180784517-180784597 ( 36) CAGCTGTC 1 chr2:209503013-209503093 ( 30) CAGCTGGG 1 chr11:62316448-62316528 ( 20) CAGCAGAG 1 chr17:61117829-61117909 ( 52) CAGCAGAG 1 chr11:60138379-60138459 ( 31) CAGCAGAG 1 chr1:206554430-206554510 ( 15) CAGCAGCC 1 chr17:75118042-75118122 ( 43) CAGCAGCC 1 chr10:80218911-80218991 ( 53) CAGCAGTC 1 chr11:75460030-75460110 ( 21) CAGCAGTC 1 chr10:45857960-45858040 ( 41) CAGCAGTC 1 chr3:17462341-17462421 ( 51) CAGCTGAC 1 chr21:44427046-44427126 ( 49) CAGCTGGC 1 chr5:19099488-19099568 ( 29) CAGCAGCA 1 chr10:126635628-12663570 ( 23) CAGCAGTA 1 chr5:180096385-180096465 ( 13) CAGCTGAA 1 chr2:234130541-234130621 ( 52) CAGCTGAA 1 chr5:74991932-74992012 ( 11) CGGCAGCG 1 chr15:79012566-79012646 ( 26) CGGCAGCG 1 chr8:102904131-102904211 ( 15) CGGCAGCG 1 chr4:77129656-77129736 ( 6) CAGCTGGA 1 chr16:75121338-75121418 ( 6) CAGCTGGA 1 chr8:103343491-103343571 ( 14) CAGCTGGA 1 chr5:65131196-65131276 ( 58) CAGCAGAA 1 chr4:175241887-175241967 ( 46) CAGCAGAA 1 chr3:186324203-186324283 ( 38) CGGCTGAG 1 chr6:158246628-158246708 ( 10) CGGCTGCC 1 chr16:3696424-3696504 ( 42) CGGCAGAG 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CAGCWGHS MEME-3 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 9.74794 E= 6.6e-006 -1204 226 -1204 -1204 157 -1204 -59 -1204 -1204 -1204 221 -1204 -1204 226 -1204 -1204 57 -1204 -1204 99 -1204 -1204 221 -1204 -28 33 -59 32 -43 33 128 -1204 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CAGCWGHS MEME-3 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 42 E= 6.6e-006 0.000000 1.000000 0.000000 0.000000 0.857143 0.000000 0.142857 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.428571 0.000000 0.000000 0.571429 0.000000 0.000000 1.000000 0.000000 0.238095 0.261905 0.142857 0.357143 0.214286 0.261905 0.523810 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CAGCWGHS MEME-3 regular expression -------------------------------------------------------------------------------- CAGC[TA]G[TCA][GCA] -------------------------------------------------------------------------------- Time 11.61 secs. ******************************************************************************** ******************************************************************************** MOTIF HCTTATCT MEME-4 width = 8 sites = 38 llr = 308 E-value = 3.3e-002 ******************************************************************************** -------------------------------------------------------------------------------- Motif HCTTATCT MEME-4 Description -------------------------------------------------------------------------------- Simplified A 2:::9::2 pos.-specific C 48::1:a: probability G 1::::::: matrix T 32aa:a:8 bits 2.3 * 2.0 * 1.8 ** ** 1.6 ** ** Relative 1.4 ****** Entropy 1.1 ******* (11.7 bits) 0.9 ******* 0.7 ******* 0.5 ******* 0.2 ******** 0.0 -------- Multilevel CCTTATCT consensus TT sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif HCTTATCT MEME-4 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr17:56465359-56465439 7 1.76e-05 AAACCA CCTTATCT GATATTTCTG chr18:20681905-20681985 1 1.76e-05 . CCTTATCT GAAATCTTGT chr21:22229401-22229481 11 1.76e-05 CAAGAATGAC CCTTATCT TATTTGCACA chr14:69616726-69616806 1 1.76e-05 . CCTTATCT GAAGCAAACA chr13:99628305-99628385 20 4.20e-05 CATTAGCTCT TCTTATCT TGTTTACCCT chr16:19000462-19000542 35 4.20e-05 TGTTTTTCCC TCTTATCT TCTAAGCCCA chr12:65050354-65050434 5 4.20e-05 ACAC TCTTATCT TCTGGTGGTG chr15:58330348-58330428 3 4.20e-05 tt tctTATCT CTTTCAACAG chr11:93811185-93811265 57 4.20e-05 accttgccta tcttatct tcctttccca chr12:8059828-8059908 19 4.20e-05 CCTGGTCAAT TCTTATCT CATTATGTCA chr6:126063718-126063798 44 4.20e-05 CTTGAACACA TCTTATCT TGTCTAACAG chr7:137729787-137729867 71 8.47e-05 actacaagtc acttatct tc chr11:62316448-62316528 52 8.47e-05 CTCAGAGCCA ACTTATCT GCTCCATTGT chr19:20344158-20344238 9 8.47e-05 ttacttaa gcttatct ccctccctca chr10:80218911-80218991 13 8.47e-05 TCCTCCCTCC ACTTATCT CTGTTTGAAC chr5:126219638-126219718 50 8.47e-05 ACTCACTTGG GCTTATCT GCCTGAGTCT chr20:46234651-46234731 61 8.47e-05 ttatttactt acttatct gcttacttgc chr8:129541424-129541504 46 8.47e-05 TTTCCAAGAG GCTTATCT AAAACAAAGA chr1:101602358-101602438 35 8.47e-05 ACCCAAAACT GCTTATCT GTGTGGTTTT chr5:131636379-131636459 25 1.09e-04 GGGTAAGGGC CTTTATCT GTCTCTGCAG chr1:198638384-198638464 36 1.09e-04 GCATAAGGCT CTTTATCT CTGACTGGTC chr17:73068150-73068230 19 1.09e-04 AAACGGTGAG CTTTATCT TATGTTATTT chrX:69440347-69440427 48 1.09e-04 ATGCCTCACT CTTTATCT CCGAGATCTG chr16:33407385-33407465 35 1.09e-04 ttactcgttg ctttatct ctagtgccca chr5:19099488-19099568 19 1.27e-04 caactaccac ccttatca gtcagcagca chr3:183048845-183048925 28 1.27e-04 ccaaccacca ccttatca aactctcaca chr3:197159785-197159865 24 1.60e-04 GATACTAGCT TTTTATCt gtctcagtct chr22:23001266-23001346 23 1.85e-04 tagcatcaat tcttatca aactctgaaa chr2:205935791-205935871 36 1.85e-04 TTGGCTTCTT TCTTATCA CTGTGGACTC chrX:46907612-46907692 37 1.85e-04 acaaagacac tcttatca ggcaggacat chr1:167713036-167713116 38 1.85e-04 aggtaaacag tcttatca tcagcaaaca chr2:200767332-200767412 54 1.98e-04 ttgttcagat ccttctct gtgaccctgt chr1:154159364-154159444 49 1.98e-04 ACTCCCTCCT CCTTCTCT ACTGCTTATA chr2:223743155-223743235 2 1.98e-04 G CCTTCTCT GCAGCCTTGT chrX:119683983-119684063 43 2.57e-04 AGTCAACACT ATTTATCT CCCAACCACT chr10:123822872-12382295 26 2.57e-04 CTGACTCATT ATTTATCT TTGGCAGGAA chr1:180784517-180784597 51 2.57e-04 GTCTATCCTT ATTTATCT TCCAGCGGGT chr8:99539058-99539138 31 3.17e-04 TTGAAGTCTT GCTTATCA AAGTAGTCCA -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif HCTTATCT MEME-4 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr17:56465359-56465439 1.8e-05 6_[+4]_66 chr18:20681905-20681985 1.8e-05 [+4]_72 chr21:22229401-22229481 1.8e-05 10_[+4]_62 chr14:69616726-69616806 1.8e-05 [+4]_72 chr13:99628305-99628385 4.2e-05 19_[+4]_53 chr16:19000462-19000542 4.2e-05 34_[+4]_38 chr12:65050354-65050434 4.2e-05 4_[+4]_68 chr15:58330348-58330428 4.2e-05 2_[+4]_70 chr11:93811185-93811265 4.2e-05 56_[+4]_16 chr12:8059828-8059908 4.2e-05 18_[+4]_54 chr6:126063718-126063798 4.2e-05 43_[+4]_29 chr7:137729787-137729867 8.5e-05 70_[+4]_2 chr11:62316448-62316528 8.5e-05 51_[+4]_21 chr19:20344158-20344238 8.5e-05 8_[+4]_64 chr10:80218911-80218991 8.5e-05 12_[+4]_60 chr5:126219638-126219718 8.5e-05 49_[+4]_23 chr20:46234651-46234731 8.5e-05 60_[+4]_12 chr8:129541424-129541504 8.5e-05 45_[+4]_27 chr1:101602358-101602438 8.5e-05 34_[+4]_38 chr5:131636379-131636459 0.00011 24_[+4]_48 chr1:198638384-198638464 0.00011 35_[+4]_37 chr17:73068150-73068230 0.00011 18_[+4]_54 chrX:69440347-69440427 0.00011 47_[+4]_25 chr16:33407385-33407465 0.00011 34_[+4]_38 chr5:19099488-19099568 0.00013 18_[+4]_54 chr3:183048845-183048925 0.00013 27_[+4]_45 chr3:197159785-197159865 0.00016 23_[+4]_49 chr22:23001266-23001346 0.00018 22_[+4]_50 chr2:205935791-205935871 0.00018 35_[+4]_37 chrX:46907612-46907692 0.00018 36_[+4]_36 chr1:167713036-167713116 0.00018 37_[+4]_35 chr2:200767332-200767412 0.0002 53_[+4]_19 chr1:154159364-154159444 0.0002 48_[+4]_24 chr2:223743155-223743235 0.0002 1_[+4]_71 chrX:119683983-119684063 0.00026 42_[+4]_30 chr10:123822872-12382295 0.00026 25_[+4]_47 chr1:180784517-180784597 0.00026 50_[+4]_22 chr8:99539058-99539138 0.00032 30_[+4]_42 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif HCTTATCT MEME-4 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF HCTTATCT width=8 seqs=38 chr17:56465359-56465439 ( 7) CCTTATCT 1 chr18:20681905-20681985 ( 1) CCTTATCT 1 chr21:22229401-22229481 ( 11) CCTTATCT 1 chr14:69616726-69616806 ( 1) CCTTATCT 1 chr13:99628305-99628385 ( 20) TCTTATCT 1 chr16:19000462-19000542 ( 35) TCTTATCT 1 chr12:65050354-65050434 ( 5) TCTTATCT 1 chr15:58330348-58330428 ( 3) TCTTATCT 1 chr11:93811185-93811265 ( 57) TCTTATCT 1 chr12:8059828-8059908 ( 19) TCTTATCT 1 chr6:126063718-126063798 ( 44) TCTTATCT 1 chr7:137729787-137729867 ( 71) ACTTATCT 1 chr11:62316448-62316528 ( 52) ACTTATCT 1 chr19:20344158-20344238 ( 9) GCTTATCT 1 chr10:80218911-80218991 ( 13) ACTTATCT 1 chr5:126219638-126219718 ( 50) GCTTATCT 1 chr20:46234651-46234731 ( 61) ACTTATCT 1 chr8:129541424-129541504 ( 46) GCTTATCT 1 chr1:101602358-101602438 ( 35) GCTTATCT 1 chr5:131636379-131636459 ( 25) CTTTATCT 1 chr1:198638384-198638464 ( 36) CTTTATCT 1 chr17:73068150-73068230 ( 19) CTTTATCT 1 chrX:69440347-69440427 ( 48) CTTTATCT 1 chr16:33407385-33407465 ( 35) CTTTATCT 1 chr5:19099488-19099568 ( 19) CCTTATCA 1 chr3:183048845-183048925 ( 28) CCTTATCA 1 chr3:197159785-197159865 ( 24) TTTTATCT 1 chr22:23001266-23001346 ( 23) TCTTATCA 1 chr2:205935791-205935871 ( 36) TCTTATCA 1 chrX:46907612-46907692 ( 37) TCTTATCA 1 chr1:167713036-167713116 ( 38) TCTTATCA 1 chr2:200767332-200767412 ( 54) CCTTCTCT 1 chr1:154159364-154159444 ( 49) CCTTCTCT 1 chr2:223743155-223743235 ( 2) CCTTCTCT 1 chrX:119683983-119684063 ( 43) ATTTATCT 1 chr10:123822872-12382295 ( 26) ATTTATCT 1 chr1:180784517-180784597 ( 51) ATTTATCT 1 chr8:99539058-99539138 ( 31) GCTTATCA 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif HCTTATCT MEME-4 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 9.09987 E= 3.3e-002 -65 82 -71 14 -1189 187 -1189 -28 -1189 -1189 -1189 180 -1189 -1189 -1189 180 167 -140 -1189 -1189 -1189 -1189 -1189 180 -1189 226 -1189 -1189 -65 -1189 -1189 151 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif HCTTATCT MEME-4 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 38 E= 3.3e-002 0.184211 0.368421 0.131579 0.315789 0.000000 0.763158 0.000000 0.236842 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.921053 0.078947 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 0.184211 0.000000 0.000000 0.815789 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif HCTTATCT MEME-4 regular expression -------------------------------------------------------------------------------- [CT][CT]TTATCT -------------------------------------------------------------------------------- Time 14.78 secs. ******************************************************************************** ******************************************************************************** MOTIF STGASTCA MEME-5 width = 8 sites = 22 llr = 207 E-value = 5.1e-003 ******************************************************************************** -------------------------------------------------------------------------------- Motif STGASTCA MEME-5 Description -------------------------------------------------------------------------------- Simplified A 2::a:::a pos.-specific C 4:::4:a: probability G 4:a:6::: matrix T :a:::a:: bits 2.3 * * 2.0 * * 1.8 *** *** 1.6 *** *** Relative 1.4 ******* Entropy 1.1 ******* (13.6 bits) 0.9 ******* 0.7 ******** 0.5 ******** 0.2 ******** 0.0 -------- Multilevel CTGAGTCA consensus G C sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif STGASTCA MEME-5 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr12:104198858-10419893 14 2.80e-05 gcaagacctt ctgagtca taatgtaaac chr8:66629754-66629834 20 2.80e-05 CACTTGCAAG GTGAGTCA TTAGTAGATA chr11:59554593-59554673 35 2.80e-05 TTACTTAGAA CTGAGTCA TCCAACAATC chr7:12991278-12991358 38 2.80e-05 GGATAAGAAA GTGAGTCA TTTAAACAAA chr8:126676795-126676875 32 2.80e-05 TTGGTGTCCG CTGAGTCA CCTGTGTCAT chr20:30913768-30913848 33 2.80e-05 TGAGTAAACA GTGAGTCA GCCTCTTTCT chr5:162806746-162806826 3 2.80e-05 AG CTGAGTCA CTGTGTAAAC chr3:58457217-58457297 29 2.80e-05 TGTGTGCAGA GTGAGTCA GATGTTTGCA chr11:20499098-20499178 36 2.80e-05 AAACAGCATA GTGAGTCA TCTGTTCTTG chr17:44836152-44836232 25 2.80e-05 TGTTGAAACA GTGAGTCA GCTATAAACA chr10:127702285-12770236 50 2.80e-05 CAGCCTGCTG CTGAGTCA CAGGGAGTAA chr3:41309628-41309708 38 5.50e-05 aaagaattat ctgactca caatgtcaat chr10:123822872-12382295 16 5.50e-05 TGTCCTGCTT CTGACTCA TTATTTATCT chr13:50819360-50819440 51 5.50e-05 ggtttcagct ctgactca ctgtgtaaac chr6:133285443-133285523 31 5.50e-05 ATTTACACTG GTGACTCA AAACAAACTT chr9:110267258-110267338 30 5.50e-05 TGTTGAATTT GTGACTCA CAGCCTCTCT chr4:111028270-111028350 20 5.50e-05 ACATGTAATG CTGACTCA TAAGGGACCT chr16:31111702-31111782 39 5.50e-05 aacatccaga gtgactca gtgagtttag chr16:3696424-3696504 27 7.42e-05 ACCAGAGCAA ATGAGTCA TATGGGCCGG chr4:80769644-80769724 29 7.42e-05 tgcggacata atgagtca tgaatgaaat chr10:121593798-12159387 57 9.27e-05 tgacagaaaa atgactca gtgtgtacaa chr11:60138379-60138459 9 9.27e-05 TGTAAACA ATGACTCA CTCAAGAATT -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif STGASTCA MEME-5 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr12:104198858-10419893 2.8e-05 13_[+5]_59 chr8:66629754-66629834 2.8e-05 19_[+5]_53 chr11:59554593-59554673 2.8e-05 34_[+5]_38 chr7:12991278-12991358 2.8e-05 37_[+5]_35 chr8:126676795-126676875 2.8e-05 31_[+5]_41 chr20:30913768-30913848 2.8e-05 32_[+5]_40 chr5:162806746-162806826 2.8e-05 2_[+5]_70 chr3:58457217-58457297 2.8e-05 28_[+5]_44 chr11:20499098-20499178 2.8e-05 35_[+5]_37 chr17:44836152-44836232 2.8e-05 24_[+5]_48 chr10:127702285-12770236 2.8e-05 49_[+5]_23 chr3:41309628-41309708 5.5e-05 37_[+5]_35 chr10:123822872-12382295 5.5e-05 15_[+5]_57 chr13:50819360-50819440 5.5e-05 50_[+5]_22 chr6:133285443-133285523 5.5e-05 30_[+5]_42 chr9:110267258-110267338 5.5e-05 29_[+5]_43 chr4:111028270-111028350 5.5e-05 19_[+5]_53 chr16:31111702-31111782 5.5e-05 38_[+5]_34 chr16:3696424-3696504 7.4e-05 26_[+5]_46 chr4:80769644-80769724 7.4e-05 28_[+5]_44 chr10:121593798-12159387 9.3e-05 56_[+5]_16 chr11:60138379-60138459 9.3e-05 8_[+5]_64 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif STGASTCA MEME-5 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF STGASTCA width=8 seqs=22 chr12:104198858-10419893 ( 14) CTGAGTCA 1 chr8:66629754-66629834 ( 20) GTGAGTCA 1 chr11:59554593-59554673 ( 35) CTGAGTCA 1 chr7:12991278-12991358 ( 38) GTGAGTCA 1 chr8:126676795-126676875 ( 32) CTGAGTCA 1 chr20:30913768-30913848 ( 33) GTGAGTCA 1 chr5:162806746-162806826 ( 3) CTGAGTCA 1 chr3:58457217-58457297 ( 29) GTGAGTCA 1 chr11:20499098-20499178 ( 36) GTGAGTCA 1 chr17:44836152-44836232 ( 25) GTGAGTCA 1 chr10:127702285-12770236 ( 50) CTGAGTCA 1 chr3:41309628-41309708 ( 38) CTGACTCA 1 chr10:123822872-12382295 ( 16) CTGACTCA 1 chr13:50819360-50819440 ( 51) CTGACTCA 1 chr6:133285443-133285523 ( 31) GTGACTCA 1 chr9:110267258-110267338 ( 30) GTGACTCA 1 chr4:111028270-111028350 ( 20) CTGACTCA 1 chr16:31111702-31111782 ( 39) GTGACTCA 1 chr16:3696424-3696504 ( 27) ATGAGTCA 1 chr4:80769644-80769724 ( 29) ATGAGTCA 1 chr10:121593798-12159387 ( 57) ATGACTCA 1 chr11:60138379-60138459 ( 9) ATGACTCA 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif STGASTCA MEME-5 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 9.24634 E= 5.1e-003 -67 97 93 -1110 -1110 -1110 -1110 180 -1110 -1110 221 -1110 179 -1110 -1110 -1110 -1110 97 146 -1110 -1110 -1110 -1110 180 -1110 226 -1110 -1110 179 -1110 -1110 -1110 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif STGASTCA MEME-5 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 22 E= 5.1e-003 0.181818 0.409091 0.409091 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.409091 0.590909 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif STGASTCA MEME-5 regular expression -------------------------------------------------------------------------------- [CG]TGA[GC]TCA -------------------------------------------------------------------------------- Time 17.89 secs. ******************************************************************************** ******************************************************************************** SUMMARY OF MOTIFS ******************************************************************************** -------------------------------------------------------------------------------- Combined block diagrams: non-overlapping sites with p-value < 0.0001 -------------------------------------------------------------------------------- SEQUENCE NAME COMBINED P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr4:80769644-80769724 4.66e-02 28_[+5(7.42e-05)]_44 chr1:75155679-75155759 4.61e-02 80 chr5:34246200-34246280 3.16e-03 80 chr16:33407385-33407465 3.36e-04 21_[+1(5.05e-05)]_51 chr11:5642584-5642664 3.26e-03 12_[+2(5.16e-05)]_43_[+1(2.53e-05)]_\ 9 chr8:146180149-146180229 2.80e-04 6_[+3(1.77e-05)]_24_[+3(1.77e-05)]_\ 34 chr5:123935496-123935576 5.45e-02 80 chr14:25451991-25452071 3.30e-02 17_[+1(2.53e-05)]_55 chr6:159269616-159269696 1.85e-01 80 chr4:147257768-147257848 2.16e-03 80 chr3:186324203-186324283 2.01e-04 40_[+5(2.80e-05)]_7_[+2(8.89e-05)]_\ 17 chr4:113021007-113021087 3.52e-01 80 chr7:2551215-2551295 1.35e-02 65_[+2(7.03e-05)]_7 chr6:106525847-106525927 6.73e-02 6_[+1(5.05e-05)]_66 chr1:150450470-150450550 5.28e-02 25_[+2(2.59e-05)]_47 chr4:134185558-134185638 2.08e-03 10_[+3(1.77e-05)]_17_[+2(5.16e-05)]_\ 5_[+2(5.16e-05)]_24 chr14:69616726-69616806 4.04e-07 [+4(1.76e-05)]_2_[+2(7.03e-05)]_20_\ [+3(1.77e-05)]_34 chr1:157337842-157337922 1.64e-01 80 chr12:50635160-50635240 8.46e-03 80 chr3:99650062-99650142 7.47e-03 5_[+2(7.03e-05)]_67 chr1:101602358-101602438 1.69e-02 34_[+4(8.47e-05)]_38 chr10:112186082-11218616 4.51e-03 30_[+1(2.53e-05)]_42 chr14:23265732-23265812 1.04e-01 53_[+2(5.16e-05)]_19 chr4:77890825-77890905 1.42e-04 30_[+2(2.59e-05)]_42 chr8:131277003-131277083 7.39e-02 80 chr20:22384669-22384749 1.20e-01 38_[+2(7.03e-05)]_34 chr1:229645464-229645544 1.24e-02 28_[+2(2.59e-05)]_44 chr4:95394187-95394267 1.87e-01 80 chr6:20086193-20086273 5.10e-03 80 chr1:22740827-22740907 4.21e-02 6_[+1(2.53e-05)]_66 chr4:83806729-83806809 2.11e-02 18_[+1(8.77e-05)]_54 chr12:31430183-31430263 4.94e-02 80 chr6:43672683-43672763 2.10e-02 80 chr1:47187632-47187712 7.46e-02 80 chr10:127702285-12770236 4.24e-04 25_[+3(1.77e-05)]_16_[+5(2.80e-05)]_\ 13_[+3(5.29e-05)]_2 chr6:161971465-161971545 3.72e-02 80 chr3:141422384-141422464 3.41e-02 41_[+1(8.77e-05)]_31 chr3:138405760-138405840 1.15e-01 64_[+2(7.03e-05)]_8 chr17:44836152-44836232 1.55e-03 24_[+5(2.80e-05)]_48 chrX:69440347-69440427 3.44e-02 80 chr8:73080275-73080355 1.37e-01 80 chr7:150462899-150462979 9.79e-03 80 chr5:130648166-130648246 4.43e-02 18_[+1(8.77e-05)]_54 chr6:134519312-134519392 5.64e-03 54_[+2(2.59e-05)]_18 chr11:74770503-74770583 1.43e-02 56_[+2(2.59e-05)]_16 chr5:180313046-180313126 3.04e-03 43_[+1(2.53e-05)]_29 chr18:11923620-11923700 1.48e-01 80 chr14:60766857-60766937 9.40e-03 72_[+1(2.53e-05)] chr16:31111702-31111782 5.92e-03 24_[+2(2.59e-05)]_6_[+5(5.50e-05)]_\ 34 chr8:5997544-5997624 2.02e-01 80 chr8:27316859-27316939 6.54e-01 80 chr2:223743155-223743235 3.35e-03 80 chr10:62185283-62185363 3.00e-03 59_[+2(2.59e-05)]_13 chr2:106806681-106806761 8.98e-02 26_[+2(5.16e-05)]_46 chr6:126063718-126063798 4.45e-03 20_[+1(5.05e-05)]_15_[+4(4.20e-05)]_\ 29 chr3:141013755-141013835 4.06e-02 51_[+2(8.89e-05)]_21 chr15:82555863-82555943 1.00e-02 80 chr17:19423140-19423220 5.24e-02 80 chr19:33488142-33488222 6.90e-03 65_[+2(2.59e-05)]_7 chr21:22229401-22229481 7.90e-04 10_[+4(1.76e-05)]_62 chr3:17462341-17462421 2.85e-03 80 chr5:132385459-132385539 1.24e-02 80 chr7:72772511-72772591 1.80e-03 4_[+5(2.80e-05)]_68 chr15:66059429-66059509 8.55e-03 80 chr6:90813344-90813424 7.47e-03 46_[+2(5.16e-05)]_26 chr8:129541424-129541504 2.41e-02 45_[+4(8.47e-05)]_27 chr19:252947-253027 1.19e-02 12_[+3(1.77e-05)]_60 chr9:128300465-128300545 7.77e-03 29_[+2(5.16e-05)]_43 chr11:60138379-60138459 8.71e-05 [+2(5.16e-05)]_[+5(9.27e-05)]_14_\ [+3(8.09e-05)]_42 chr6:84144350-84144430 7.16e-03 80 chr8:102904131-102904211 7.66e-03 63_[+2(2.59e-05)]_9 chr4:111028270-111028350 2.26e-03 19_[+5(5.50e-05)]_53 chr19:29049854-29049934 2.86e-02 22_[+1(2.53e-05)]_50 chr2:36739524-36739604 4.48e-02 18_[+1(8.77e-05)]_54 chr8:94678601-94678681 2.15e-03 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chr13:24230994-24231074 1.03e-03 20_[+3(1.77e-05)]_52 chr8:42400413-42400493 2.97e-04 58_[+3(1.77e-05)]_14 chr14:88490840-88490920 1.43e-02 80 chr2:149259238-149259318 1.15e-01 80 chr16:69251545-69251625 5.77e-01 80 chr5:82561157-82561237 6.60e-03 34_[+2(2.59e-05)]_38 chr1:144881510-144881590 4.96e-03 25_[+3(7.05e-05)]_47 chr15:91056911-91056991 1.72e-02 64_[+2(2.59e-05)]_8 chr16:24998323-24998403 4.91e-02 80 chr1:116963159-116963239 3.92e-02 57_[+1(5.05e-05)]_15 chr11:75460030-75460110 3.86e-01 80 chr19:41427116-41427196 2.98e-01 80 chr4:175241887-175241967 5.46e-03 80 chr10:35331939-35332019 1.48e-02 22_[+1(2.53e-05)]_50 chr11:20111811-20111891 7.14e-04 26_[+3(1.77e-05)]_46 chr2:54799570-54799650 2.43e-03 [+1(2.53e-05)]_72 chr5:65131196-65131276 8.51e-03 15_[+1(2.53e-05)]_57 chr5:74991932-74992012 4.01e-02 80 chr8:126676795-126676875 8.07e-04 31_[+5(2.80e-05)]_41 chr6:161223124-161223204 1.69e-01 80 chr1:246445119-246445199 3.24e-02 14_[+2(2.59e-05)]_58 chr10:80218911-80218991 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******************************************************************************** Stopped because requested number of motifs (5) found. ******************************************************************************** CPU: c17n10.farnam.hpc.yale.internal ********************************************************************************