******************************************************************************** MEME - Motif discovery tool ******************************************************************************** MEME version 5.3.3 (Release date: Sun Feb 7 15:39:52 2021 -0800) For further information on how to interpret these results please access https://meme-suite.org/meme. To get a copy of the MEME Suite software please access https://meme-suite.org. ******************************************************************************** ******************************************************************************** REFERENCE ******************************************************************************** If you use this program in your research, please cite: Timothy L. Bailey and Charles Elkan, "Fitting a mixture model by expectation maximization to discover motifs in biopolymers", Proceedings of the Second International Conference on Intelligent Systems for Molecular Biology, pp. 28-36, AAAI Press, Menlo Park, California, 1994. ******************************************************************************** ******************************************************************************** TRAINING SET ******************************************************************************** PRIMARY SEQUENCES= ../result/final_prediction/K562/fasta/RankLinear0.6_40/EP300.fasta CONTROL SEQUENCES= --none-- ALPHABET= ACGT Sequence name Weight Length Sequence name Weight Length ------------- ------ ------ ------------- ------ ------ chr3:72510086-72510166 1.0000 80 chr10:21386603-21386683 1.0000 80 chr6:13980256-13980336 1.0000 80 chr9:128005735-128005815 1.0000 80 chr1:160370184-160370264 1.0000 80 chr8:102210813-102210893 1.0000 80 chr2:209794283-209794363 1.0000 80 chr5:159066115-159066195 1.0000 80 chr22:21221903-21221983 1.0000 80 chr7:86736663-86736743 1.0000 80 chr12:104531971-10453205 1.0000 80 chr3:156825712-156825792 1.0000 80 chr11:91638659-91638739 1.0000 80 chr11:46638864-46638944 1.0000 80 chr6:26332175-26332255 1.0000 80 chr2:197264976-197265056 1.0000 80 chr22:26122325-26122405 1.0000 80 chr19:823845-823925 1.0000 80 chr20:382720-382800 1.0000 80 chr20:32319994-32320074 1.0000 80 chr4:151237579-151237659 1.0000 80 chr16:69599757-69599837 1.0000 80 chr19:42514615-42514695 1.0000 80 chr9:101103890-101103970 1.0000 80 chr5:43067060-43067140 1.0000 80 chrX:11606329-11606409 1.0000 80 chr3:151961277-151961357 1.0000 80 chrX:131180713-131180793 1.0000 80 chr3:119414458-119414538 1.0000 80 chr7:135930234-135930314 1.0000 80 chr1:117388864-117388944 1.0000 80 chrX:1600783-1600863 1.0000 80 chr12:11951932-11952012 1.0000 80 chr8:8869654-8869734 1.0000 80 chr12:4647695-4647775 1.0000 80 chr4:139694602-139694682 1.0000 80 chr17:34901349-34901429 1.0000 80 chr2:43154785-43154865 1.0000 80 chr12:94151885-94151965 1.0000 80 chr10:52086765-52086845 1.0000 80 chr4:127659407-127659487 1.0000 80 chr22:21132189-21132269 1.0000 80 chr16:79897801-79897881 1.0000 80 chr12:116823768-11682384 1.0000 80 chr9:132641526-132641606 1.0000 80 chr1:12805381-12805461 1.0000 80 chr5:149319759-149319839 1.0000 80 chr17:38804172-38804252 1.0000 80 chr1:246741200-246741280 1.0000 80 chr11:86642692-86642772 1.0000 80 chr8:41909520-41909600 1.0000 80 chr12:121581778-12158185 1.0000 80 chr3:119357855-119357935 1.0000 80 chr18:3603156-3603236 1.0000 80 chr8:135725183-135725263 1.0000 80 chr9:119157779-119157859 1.0000 80 chr22:40316294-40316374 1.0000 80 chr2:196351889-196351969 1.0000 80 chr13:37574762-37574842 1.0000 80 chr17:38673180-38673260 1.0000 80 chr9:114835401-114835481 1.0000 80 chr15:57614465-57614545 1.0000 80 chr16:84571383-84571463 1.0000 80 chr13:109421965-10942204 1.0000 80 chr1:207483425-207483505 1.0000 80 chr8:94564279-94564359 1.0000 80 chr12:47754637-47754717 1.0000 80 chr11:3941484-3941564 1.0000 80 chr18:1464602-1464682 1.0000 80 chr6:25910641-25910721 1.0000 80 chr2:231524060-231524140 1.0000 80 chr6:119460527-119460607 1.0000 80 chr18:967175-967255 1.0000 80 chr6:40346042-40346122 1.0000 80 chr17:900265-900345 1.0000 80 chr12:102823621-10282370 1.0000 80 chr2:58958091-58958171 1.0000 80 chr5:138855128-138855208 1.0000 80 chr6:147483244-147483324 1.0000 80 chr2:198794136-198794216 1.0000 80 chr6:10402006-10402086 1.0000 80 chr3:137918866-137918946 1.0000 80 chr9:123659625-123659705 1.0000 80 chr10:5504471-5504551 1.0000 80 chr1:40525261-40525341 1.0000 80 chr9:130301902-130301982 1.0000 80 chr13:30030768-30030848 1.0000 80 chr4:56596121-56596201 1.0000 80 chr11:34831305-34831385 1.0000 80 chr5:43772956-43773036 1.0000 80 chr10:103872257-10387233 1.0000 80 chrX:11385890-11385970 1.0000 80 chr14:101237703-10123778 1.0000 80 chr4:80928215-80928295 1.0000 80 chr6:43894503-43894583 1.0000 80 chr16:56015641-56015721 1.0000 80 chr9:97041199-97041279 1.0000 80 chr6:82915921-82916001 1.0000 80 chr4:2397462-2397542 1.0000 80 chr17:40540729-40540809 1.0000 80 chr19:50427731-50427811 1.0000 80 chr16:71526120-71526200 1.0000 80 chrX:65218084-65218164 1.0000 80 chr3:99536469-99536549 1.0000 80 chr12:123942623-12394270 1.0000 80 chr21:31021826-31021906 1.0000 80 chr11:82503022-82503102 1.0000 80 chr8:130468563-130468643 1.0000 80 chr17:53894347-53894427 1.0000 80 chr2:15696593-15696673 1.0000 80 chr16:56496480-56496560 1.0000 80 chr11:78003375-78003455 1.0000 80 chr2:192701674-192701754 1.0000 80 chr8:125019794-125019874 1.0000 80 chr7:120681987-120682067 1.0000 80 chr11:73495515-73495595 1.0000 80 chr5:81054736-81054816 1.0000 80 chr16:11707753-11707833 1.0000 80 chr6:14453043-14453123 1.0000 80 chr2:145338453-145338533 1.0000 80 chr2:138777007-138777087 1.0000 80 chr9:138842326-138842406 1.0000 80 chr11:78001417-78001497 1.0000 80 chr4:129438338-129438418 1.0000 80 chr11:59735639-59735719 1.0000 80 chr11:16359521-16359601 1.0000 80 chr4:81048660-81048740 1.0000 80 chr20:49650409-49650489 1.0000 80 chr1:201536255-201536335 1.0000 80 chr7:8802534-8802614 1.0000 80 chr1:15110666-15110746 1.0000 80 chr2:106217573-106217653 1.0000 80 chr12:60538342-60538422 1.0000 80 chr22:22302158-22302238 1.0000 80 chr11:46264886-46264966 1.0000 80 chr8:130594504-130594584 1.0000 80 chr6:28534080-28534160 1.0000 80 chr10:119171078-11917115 1.0000 80 chr12:94316420-94316500 1.0000 80 chr20:3993447-3993527 1.0000 80 chr12:101801661-10180174 1.0000 80 chr3:65573864-65573944 1.0000 80 chrX:151345708-151345788 1.0000 80 chr2:134906777-134906857 1.0000 80 chr7:29833281-29833361 1.0000 80 chr2:55343355-55343435 1.0000 80 chr9:100705723-100705803 1.0000 80 chr15:34946969-34947049 1.0000 80 chr3:128134933-128135013 1.0000 80 chr22:22146158-22146238 1.0000 80 chr12:23875689-23875769 1.0000 80 chr1:38989340-38989420 1.0000 80 chr2:178130730-178130810 1.0000 80 chr15:58472063-58472143 1.0000 80 chr5:78067255-78067335 1.0000 80 chr6:138225787-138225867 1.0000 80 chrX:129890394-129890474 1.0000 80 chr3:170496595-170496675 1.0000 80 chr6:135628024-135628104 1.0000 80 chr20:52534057-52534137 1.0000 80 chr1:100813069-100813149 1.0000 80 chr7:112782514-112782594 1.0000 80 chr5:171381081-171381161 1.0000 80 chr4:127656674-127656754 1.0000 80 chr1:90169221-90169301 1.0000 80 chr7:91184359-91184439 1.0000 80 chr16:11196067-11196147 1.0000 80 chr17:46624482-46624562 1.0000 80 chr2:38871039-38871119 1.0000 80 chr8:91209728-91209808 1.0000 80 chr5:111885602-111885682 1.0000 80 chr10:17038367-17038447 1.0000 80 chrX:65229242-65229322 1.0000 80 chrX:40032085-40032165 1.0000 80 chr3:150169167-150169247 1.0000 80 chr16:9692097-9692177 1.0000 80 chr4:123670886-123670966 1.0000 80 chr12:9917530-9917610 1.0000 80 chr12:56520681-56520761 1.0000 80 chr22:22139121-22139201 1.0000 80 chr8:129440525-129440605 1.0000 80 chr1:95551140-95551220 1.0000 80 chr6:126433556-126433636 1.0000 80 chr12:89934483-89934563 1.0000 80 chr1:176849123-176849203 1.0000 80 chr3:43712831-43712911 1.0000 80 chr9:101630140-101630220 1.0000 80 chr6:37151138-37151218 1.0000 80 chr16:1543440-1543520 1.0000 80 chr1:61636434-61636514 1.0000 80 chr6:150597514-150597594 1.0000 80 chr1:29359598-29359678 1.0000 80 chr4:159963510-159963590 1.0000 80 chr10:21419203-21419283 1.0000 80 chr6:7199418-7199498 1.0000 80 chr5:89954561-89954641 1.0000 80 chr10:104748879-10474895 1.0000 80 chrX:154027482-154027562 1.0000 80 chr3:137906209-137906289 1.0000 80 chr3:154736918-154736998 1.0000 80 chr3:171146193-171146273 1.0000 80 chr1:221881521-221881601 1.0000 80 chr12:92751826-92751906 1.0000 80 chr4:175204943-175205023 1.0000 80 chr2:97560979-97561059 1.0000 80 chr19:29096656-29096736 1.0000 80 chr6:134279197-134279277 1.0000 80 chr8:86290472-86290552 1.0000 80 chr2:8817909-8817989 1.0000 80 chr4:8481024-8481104 1.0000 80 chr2:152639287-152639367 1.0000 80 chr6:125628625-125628705 1.0000 80 chr22:47000433-47000513 1.0000 80 chr14:68103314-68103394 1.0000 80 chr6:135642624-135642704 1.0000 80 chr12:63304476-63304556 1.0000 80 chr9:100700552-100700632 1.0000 80 chr9:251546-251626 1.0000 80 chr3:77228986-77229066 1.0000 80 chr6:41293349-41293429 1.0000 80 chr7:2062732-2062812 1.0000 80 chr21:31014416-31014496 1.0000 80 chr17:25929817-25929897 1.0000 80 chr1:182308177-182308257 1.0000 80 chr11:38560557-38560637 1.0000 80 chr20:352622-352702 1.0000 80 chr14:64746987-64747067 1.0000 80 chr8:130570161-130570241 1.0000 80 chr12:7446436-7446516 1.0000 80 chr8:2591456-2591536 1.0000 80 chrX:65235147-65235227 1.0000 80 chr14:71828204-71828284 1.0000 80 chr6:158327673-158327753 1.0000 80 chr6:45404704-45404784 1.0000 80 chr22:18156026-18156106 1.0000 80 chr1:51895756-51895836 1.0000 80 chr19:45596216-45596296 1.0000 80 chr20:39890785-39890865 1.0000 80 chr6:14951039-14951119 1.0000 80 chr11:62164298-62164378 1.0000 80 chr20:51797654-51797734 1.0000 80 chr5:89940136-89940216 1.0000 80 chr1:202045348-202045428 1.0000 80 chr12:1413619-1413699 1.0000 80 chr15:34949831-34949911 1.0000 80 chr3:127729207-127729287 1.0000 80 chr6:134636498-134636578 1.0000 80 chrX:15534176-15534256 1.0000 80 chr17:27621383-27621463 1.0000 80 chr6:20458733-20458813 1.0000 80 ******************************************************************************** ******************************************************************************** COMMAND LINE SUMMARY ******************************************************************************** This information can also be useful in the event you wish to report a problem with the MEME software. command: meme -oc ../result/final_prediction/K562/inference_raw/MEME/RankLinear0.6_40_EP300/ -dna -nmotifs 5 -w 8 -maxsize 250000 -nostatus ../result/final_prediction/K562/fasta/RankLinear0.6_40/EP300.fasta model: mod= zoops nmotifs= 5 evt= inf objective function: em= E-value of product of p-values starts= E-value of product of p-values strands: + width: minw= 8 maxw= 8 nsites: minsites= 2 maxsites= 250 wnsites= 0.8 theta: spmap= uni spfuzz= 0.5 em: prior= dirichlet b= 0.01 maxiter= 50 distance= 1e-05 trim: wg= 11 ws= 1 endgaps= yes data: n= 20000 N= 250 sample: seed= 0 hsfrac= 0 searchsize= 20000 norand= no csites= 1000 Letter frequencies in dataset: A 0.266 C 0.231 G 0.231 T 0.272 Background letter frequencies (from file dataset with add-one prior applied): A 0.266 C 0.231 G 0.231 T 0.272 Background model order: 0 ******************************************************************************** ******************************************************************************** MOTIF BAGATAAG MEME-1 width = 8 sites = 88 llr = 670 E-value = 1.1e-038 ******************************************************************************** -------------------------------------------------------------------------------- Motif BAGATAAG MEME-1 Description -------------------------------------------------------------------------------- Simplified A 17:a:9a2 pos.-specific C 41:::::2 probability G 3:a::::6 matrix T 22::a1:: bits 2.1 * 1.9 *** * 1.7 ***** 1.5 ***** Relative 1.3 ***** Entropy 1.1 ***** (11.0 bits) 0.8 ****** 0.6 ******* 0.4 ******* 0.2 ******** 0.0 -------- Multilevel CAGATAAG consensus GT sequence T -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif BAGATAAG MEME-1 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr6:134636498-134636578 57 1.68e-05 TGCATGTACT CAGATAAG ACATCAGTAC chr11:62164298-62164378 33 1.68e-05 GTGCAGAACT CAGATAAG TGTTAGAGTT chr14:71828204-71828284 66 1.68e-05 GTGTGACTAC CAGATAAG TCATTAC chr3:150169167-150169247 53 1.68e-05 AGGAATTTGC CAGATAAG ATAAATGGCA chrX:65218084-65218164 70 1.68e-05 GAGGTGGTGG CAGATAAG CCA chr11:34831305-34831385 43 1.68e-05 ctgtttattg cagataag gaggctggtt chr1:40525261-40525341 7 1.68e-05 TGTGAA CAGATAAG AGAGGAAATG chr2:198794136-198794216 61 1.68e-05 CTGTTATTAG CAGATAAG CAGGAGTGGC chr6:20458733-20458813 31 3.36e-05 GTGGACCTTG GAGATAAG CTTCTATTCT chrX:15534176-15534256 58 3.36e-05 CTGCTCCTCA GAGATAAG GGGTAACCCC chr6:158327673-158327753 23 3.36e-05 CTGTCAAATT GAGATAAG GAGCTACCAA chr8:130570161-130570241 34 3.36e-05 agggtcaaat gagataag ttctttatct chr1:221881521-221881601 19 3.36e-05 ATAGTTCCAG GAGATAAG GCAGAAAACC chr1:176849123-176849203 68 3.36e-05 CTGGGCAGAA GAGATAAG CCCTG chr22:22139121-22139201 7 3.36e-05 ttttaa gagataag agtgtcaccg chr12:60538342-60538422 44 3.36e-05 ttggctcagc gagataag aaataagggg chr11:16359521-16359601 68 3.36e-05 CTGTACCCAA GAGATAAG AAACT chr14:101237703-10123778 59 3.36e-05 cctgtccttg gagataag agtggcagtt chr9:132641526-132641606 69 3.36e-05 GCTGCCAGCA GAGATAAG GGCA chr4:139694602-139694682 60 3.36e-05 CTGGGAACCA GAGATAAG ATAGGGTTTC chr11:38560557-38560637 10 5.33e-05 tgcttggtt tagataag cacttcaaag chr10:104748879-10474895 48 5.33e-05 TATGTCTATT TAGATAAG CAAACTACTG chr6:138225787-138225867 24 5.33e-05 ATTGCATGCC TAGATAAG GCAGTTACAT chr1:38989340-38989420 67 5.33e-05 ctctacccat tagataag aacttt chr2:196351889-196351969 49 5.33e-05 CTGAATTCAT TAGATAAG GGAAATGAGT chr1:202045348-202045428 27 8.98e-05 GGCTGGGCTG AAGATAAG AGGCAGCTGT chr17:25929817-25929897 37 8.98e-05 gtgcatttcc ctgataag aaggcccacg chr8:86290472-86290552 53 8.98e-05 gtgtgagaac ctgataag ggaagtggtt chr19:29096656-29096736 1 8.98e-05 . CTGATAAG GACTTAAAAT chr1:29359598-29359678 65 8.98e-05 CTGGTTTACA AAGATAAG CTGAGAAT chr3:43712831-43712911 3 8.98e-05 AG CTGATAAG CACACCGACA chr16:11196067-11196147 31 8.98e-05 CACAGCTGTG CTGATAAG ATTGCGTTTC chr2:55343355-55343435 49 8.98e-05 GGACCAGCAG CTGATAAG ACTCTGGCTG chr2:15696593-15696673 47 8.98e-05 ATGGACATTC AAGATAAG CCTGAGAATA chr6:43894503-43894583 73 8.98e-05 TAACCCAAGC CTGATAAG chr4:56596121-56596201 65 8.98e-05 gcattccttc ctgataag agaccatg chr2:231524060-231524140 29 8.98e-05 CTGATAAGTG AAGATAAG GGCTCAGAGG chrX:131180713-131180793 57 8.98e-05 TAGGTGGGTA AAGATAAG GAGTCAACTG chr22:26122325-26122405 31 8.98e-05 GTGCTGGTGT AAGATAAG AGTTATCTTG chr22:21221903-21221983 63 8.98e-05 CCTCACAGGC AAGATAAG CCACCCTCAC chr10:21386603-21386683 22 8.98e-05 GTAAACAGAA AAGATAAG TCTCGGTCAA chr2:8817909-8817989 61 1.07e-04 GCTGCTAAAC CAGATAAC AGGACCGGGA chr3:154736918-154736998 69 1.07e-04 ACTGTTAGAG CAGATAAC CTTG chr15:58472063-58472143 36 1.07e-04 TGCAGGAACA CAGATAAC GTGTGAGTAA chr4:2397462-2397542 46 1.07e-04 CCACCACACC CAGATAAC GGTCCAAGAT chr10:103872257-10387233 37 1.07e-04 TGTGGCCTAC CAGATAAC CAGTTGGGCC chr12:56520681-56520761 46 1.26e-04 CCTGCAGAAC CAGATAAA ATTTATCAGC chr18:3603156-3603236 30 1.26e-04 GTCAGGTCAC CAGATAAA GGCAAGTCTT chr12:47754637-47754717 64 1.43e-04 ATGTTTTGCA GTGATAAG ATACGGGCA chr6:26332175-26332255 67 1.60e-04 TCTTTTCTGA GAGATAAC GGCGCC chr12:63304476-63304556 7 1.99e-04 TATCTC TTGATAAG AAAAACGGTC chr6:150597514-150597594 67 1.99e-04 TCTGGCCAGT TTGATAAG AGGAGT chr12:89934483-89934563 63 1.99e-04 gactatattt gagataaa tacctccagc chr12:23875689-23875769 41 1.99e-04 CCTGCATTCC TTGATAAG TGGCAAAGCT chr2:134906777-134906857 43 1.99e-04 ctgttaggtg gagataaa gaaagcttcc chr4:80928215-80928295 65 1.99e-04 CAACTGCTCT GAGATAAA GGATTGTC chr1:90169221-90169301 29 2.19e-04 taagaaatta tagataac atctagaaga chr9:100705723-100705803 59 2.19e-04 TGTACACATA TAGATAAC ATGTTCTATA chr7:29833281-29833361 66 2.19e-04 CTTTAAAGTG TAGATAAC AGAGGTG chr2:192701674-192701754 65 2.19e-04 GGAAGCTGCC TAGATAAC AGAGCTAA chr6:13980256-13980336 47 2.19e-04 CTGTTAGCTT TAGATAAC GGCAAACATG chr20:51797654-51797734 45 2.42e-04 ctggccccgc tagataaa gaatctcttc chr6:41293349-41293429 15 2.42e-04 GGATTTGTCC TAGATAAA TGTGGCGGGT chr17:53894347-53894427 73 2.42e-04 TATGGTCTGT TAGATAAA chr3:128134933-128135013 41 2.76e-04 CCAGGCCCCG ATGATAAG ACAGACAAGC chr4:127659407-127659487 56 2.76e-04 ACCAATGCTT CCGATAAG ATACACAGGA chr22:40316294-40316374 67 3.13e-04 AATGTGTGAA CTGATAAC ACATCT chr15:34949831-34949911 48 3.55e-04 gtcagttacc aagataaa gaaagccgag chr6:7199418-7199498 5 3.55e-04 AGGG CTGATAAA GGATACTCCC chr22:22146158-22146238 64 3.55e-04 aatggggcaa aagataaa aaatcggtg chr22:22302158-22302238 69 3.55e-04 TGGAAGCCTA AAGATAAA AAAC chr16:56496480-56496560 73 3.55e-04 ACTGGTAAGG AAGATAAA chr9:114835401-114835481 30 3.55e-04 CTGGACCTCT CTGATAAA GTGACAATCT chrX:40032085-40032165 29 3.69e-04 CTGACACTGG GCGATAAG GAGTTCCTCG chr9:138842326-138842406 2 3.69e-04 a gcgataag cctataagaa chr12:116823768-11682384 53 3.69e-04 TGGGTCATTG GCGATAAG GGCAGGTTGG chr17:46624482-46624562 67 3.87e-04 ATTTTATGGC CAGATTAG CAAACA chr18:1464602-1464682 51 3.87e-04 GTAATCTCAT CAGATTAG CATGACTGTT chr13:109421965-10942204 57 3.87e-04 tctggaataa cagattag aaagacagtt chr9:251546-251626 43 4.04e-04 GATGCGCCTG GTGATAAC ATTTTCCAGT chr21:31014416-31014496 60 4.41e-04 AGTGTACATA TCGATAAG GAGTCACGGG chr6:135642624-135642704 54 4.60e-04 GTGCCAAAGA CAGATAAT TTTATCTAGG chr1:246741200-246741280 58 4.60e-04 TGTTTCCTAC CAGATAAT ACTTGTGGTT chr8:8869654-8869734 18 4.98e-04 gcggtcaggc ttgataac cacCACTGTG chr7:91184359-91184439 37 5.21e-04 TCCTAATGGC TTGATAAA TATTCCTGCC chr8:130468563-130468643 31 5.78e-04 actctcaggt tagattag ctgccccctt chr5:149319759-149319839 17 5.78e-04 ctgtgaaaca gagataat gacagttatg chr5:81054736-81054816 58 7.12e-04 CCTAAACCTC CTGATTAG ATCAGAAACA -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif BAGATAAG MEME-1 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr6:134636498-134636578 1.7e-05 56_[+1]_16 chr11:62164298-62164378 1.7e-05 32_[+1]_40 chr14:71828204-71828284 1.7e-05 65_[+1]_7 chr3:150169167-150169247 1.7e-05 52_[+1]_20 chrX:65218084-65218164 1.7e-05 69_[+1]_3 chr11:34831305-34831385 1.7e-05 42_[+1]_30 chr1:40525261-40525341 1.7e-05 6_[+1]_66 chr2:198794136-198794216 1.7e-05 60_[+1]_12 chr6:20458733-20458813 3.4e-05 30_[+1]_42 chrX:15534176-15534256 3.4e-05 57_[+1]_15 chr6:158327673-158327753 3.4e-05 22_[+1]_50 chr8:130570161-130570241 3.4e-05 33_[+1]_39 chr1:221881521-221881601 3.4e-05 18_[+1]_54 chr1:176849123-176849203 3.4e-05 67_[+1]_5 chr22:22139121-22139201 3.4e-05 6_[+1]_66 chr12:60538342-60538422 3.4e-05 43_[+1]_29 chr11:16359521-16359601 3.4e-05 67_[+1]_5 chr14:101237703-10123778 3.4e-05 58_[+1]_14 chr9:132641526-132641606 3.4e-05 68_[+1]_4 chr4:139694602-139694682 3.4e-05 59_[+1]_13 chr11:38560557-38560637 5.3e-05 9_[+1]_63 chr10:104748879-10474895 5.3e-05 47_[+1]_25 chr6:138225787-138225867 5.3e-05 23_[+1]_49 chr1:38989340-38989420 5.3e-05 66_[+1]_6 chr2:196351889-196351969 5.3e-05 48_[+1]_24 chr1:202045348-202045428 9e-05 26_[+1]_46 chr17:25929817-25929897 9e-05 36_[+1]_36 chr8:86290472-86290552 9e-05 52_[+1]_20 chr19:29096656-29096736 9e-05 [+1]_72 chr1:29359598-29359678 9e-05 64_[+1]_8 chr3:43712831-43712911 9e-05 2_[+1]_70 chr16:11196067-11196147 9e-05 30_[+1]_42 chr2:55343355-55343435 9e-05 48_[+1]_24 chr2:15696593-15696673 9e-05 46_[+1]_26 chr6:43894503-43894583 9e-05 72_[+1] chr4:56596121-56596201 9e-05 64_[+1]_8 chr2:231524060-231524140 9e-05 28_[+1]_44 chrX:131180713-131180793 9e-05 56_[+1]_16 chr22:26122325-26122405 9e-05 30_[+1]_42 chr22:21221903-21221983 9e-05 62_[+1]_10 chr10:21386603-21386683 9e-05 21_[+1]_51 chr2:8817909-8817989 0.00011 60_[+1]_12 chr3:154736918-154736998 0.00011 68_[+1]_4 chr15:58472063-58472143 0.00011 35_[+1]_37 chr4:2397462-2397542 0.00011 45_[+1]_27 chr10:103872257-10387233 0.00011 36_[+1]_36 chr12:56520681-56520761 0.00013 45_[+1]_27 chr18:3603156-3603236 0.00013 29_[+1]_43 chr12:47754637-47754717 0.00014 63_[+1]_9 chr6:26332175-26332255 0.00016 66_[+1]_6 chr12:63304476-63304556 0.0002 6_[+1]_66 chr6:150597514-150597594 0.0002 66_[+1]_6 chr12:89934483-89934563 0.0002 62_[+1]_10 chr12:23875689-23875769 0.0002 40_[+1]_32 chr2:134906777-134906857 0.0002 42_[+1]_30 chr4:80928215-80928295 0.0002 64_[+1]_8 chr1:90169221-90169301 0.00022 28_[+1]_44 chr9:100705723-100705803 0.00022 58_[+1]_14 chr7:29833281-29833361 0.00022 65_[+1]_7 chr2:192701674-192701754 0.00022 64_[+1]_8 chr6:13980256-13980336 0.00022 46_[+1]_26 chr20:51797654-51797734 0.00024 44_[+1]_28 chr6:41293349-41293429 0.00024 14_[+1]_58 chr17:53894347-53894427 0.00024 72_[+1] chr3:128134933-128135013 0.00028 40_[+1]_32 chr4:127659407-127659487 0.00028 55_[+1]_17 chr22:40316294-40316374 0.00031 66_[+1]_6 chr15:34949831-34949911 0.00035 47_[+1]_25 chr6:7199418-7199498 0.00035 4_[+1]_68 chr22:22146158-22146238 0.00035 63_[+1]_9 chr22:22302158-22302238 0.00035 68_[+1]_4 chr16:56496480-56496560 0.00035 72_[+1] chr9:114835401-114835481 0.00035 29_[+1]_43 chrX:40032085-40032165 0.00037 28_[+1]_44 chr9:138842326-138842406 0.00037 1_[+1]_71 chr12:116823768-11682384 0.00037 52_[+1]_20 chr17:46624482-46624562 0.00039 66_[+1]_6 chr18:1464602-1464682 0.00039 50_[+1]_22 chr13:109421965-10942204 0.00039 56_[+1]_16 chr9:251546-251626 0.0004 42_[+1]_30 chr21:31014416-31014496 0.00044 59_[+1]_13 chr6:135642624-135642704 0.00046 53_[+1]_19 chr1:246741200-246741280 0.00046 57_[+1]_15 chr8:8869654-8869734 0.0005 17_[+1]_55 chr7:91184359-91184439 0.00052 36_[+1]_36 chr8:130468563-130468643 0.00058 30_[+1]_42 chr5:149319759-149319839 0.00058 16_[+1]_56 chr5:81054736-81054816 0.00071 57_[+1]_15 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif BAGATAAG MEME-1 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF BAGATAAG width=8 seqs=88 chr6:134636498-134636578 ( 57) CAGATAAG 1 chr11:62164298-62164378 ( 33) CAGATAAG 1 chr14:71828204-71828284 ( 66) CAGATAAG 1 chr3:150169167-150169247 ( 53) CAGATAAG 1 chrX:65218084-65218164 ( 70) CAGATAAG 1 chr11:34831305-34831385 ( 43) CAGATAAG 1 chr1:40525261-40525341 ( 7) CAGATAAG 1 chr2:198794136-198794216 ( 61) CAGATAAG 1 chr6:20458733-20458813 ( 31) GAGATAAG 1 chrX:15534176-15534256 ( 58) GAGATAAG 1 chr6:158327673-158327753 ( 23) GAGATAAG 1 chr8:130570161-130570241 ( 34) GAGATAAG 1 chr1:221881521-221881601 ( 19) GAGATAAG 1 chr1:176849123-176849203 ( 68) GAGATAAG 1 chr22:22139121-22139201 ( 7) GAGATAAG 1 chr12:60538342-60538422 ( 44) GAGATAAG 1 chr11:16359521-16359601 ( 68) GAGATAAG 1 chr14:101237703-10123778 ( 59) GAGATAAG 1 chr9:132641526-132641606 ( 69) GAGATAAG 1 chr4:139694602-139694682 ( 60) GAGATAAG 1 chr11:38560557-38560637 ( 10) TAGATAAG 1 chr10:104748879-10474895 ( 48) TAGATAAG 1 chr6:138225787-138225867 ( 24) TAGATAAG 1 chr1:38989340-38989420 ( 67) TAGATAAG 1 chr2:196351889-196351969 ( 49) TAGATAAG 1 chr1:202045348-202045428 ( 27) AAGATAAG 1 chr17:25929817-25929897 ( 37) CTGATAAG 1 chr8:86290472-86290552 ( 53) CTGATAAG 1 chr19:29096656-29096736 ( 1) CTGATAAG 1 chr1:29359598-29359678 ( 65) AAGATAAG 1 chr3:43712831-43712911 ( 3) CTGATAAG 1 chr16:11196067-11196147 ( 31) CTGATAAG 1 chr2:55343355-55343435 ( 49) CTGATAAG 1 chr2:15696593-15696673 ( 47) AAGATAAG 1 chr6:43894503-43894583 ( 73) CTGATAAG 1 chr4:56596121-56596201 ( 65) CTGATAAG 1 chr2:231524060-231524140 ( 29) AAGATAAG 1 chrX:131180713-131180793 ( 57) AAGATAAG 1 chr22:26122325-26122405 ( 31) AAGATAAG 1 chr22:21221903-21221983 ( 63) AAGATAAG 1 chr10:21386603-21386683 ( 22) AAGATAAG 1 chr2:8817909-8817989 ( 61) CAGATAAC 1 chr3:154736918-154736998 ( 69) CAGATAAC 1 chr15:58472063-58472143 ( 36) CAGATAAC 1 chr4:2397462-2397542 ( 46) CAGATAAC 1 chr10:103872257-10387233 ( 37) CAGATAAC 1 chr12:56520681-56520761 ( 46) CAGATAAA 1 chr18:3603156-3603236 ( 30) CAGATAAA 1 chr12:47754637-47754717 ( 64) GTGATAAG 1 chr6:26332175-26332255 ( 67) GAGATAAC 1 chr12:63304476-63304556 ( 7) TTGATAAG 1 chr6:150597514-150597594 ( 67) TTGATAAG 1 chr12:89934483-89934563 ( 63) GAGATAAA 1 chr12:23875689-23875769 ( 41) TTGATAAG 1 chr2:134906777-134906857 ( 43) GAGATAAA 1 chr4:80928215-80928295 ( 65) GAGATAAA 1 chr1:90169221-90169301 ( 29) TAGATAAC 1 chr9:100705723-100705803 ( 59) TAGATAAC 1 chr7:29833281-29833361 ( 66) TAGATAAC 1 chr2:192701674-192701754 ( 65) TAGATAAC 1 chr6:13980256-13980336 ( 47) TAGATAAC 1 chr20:51797654-51797734 ( 45) TAGATAAA 1 chr6:41293349-41293429 ( 15) TAGATAAA 1 chr17:53894347-53894427 ( 73) TAGATAAA 1 chr3:128134933-128135013 ( 41) ATGATAAG 1 chr4:127659407-127659487 ( 56) CCGATAAG 1 chr22:40316294-40316374 ( 67) CTGATAAC 1 chr15:34949831-34949911 ( 48) AAGATAAA 1 chr6:7199418-7199498 ( 5) CTGATAAA 1 chr22:22146158-22146238 ( 64) AAGATAAA 1 chr22:22302158-22302238 ( 69) AAGATAAA 1 chr16:56496480-56496560 ( 73) AAGATAAA 1 chr9:114835401-114835481 ( 30) CTGATAAA 1 chrX:40032085-40032165 ( 29) GCGATAAG 1 chr9:138842326-138842406 ( 2) GCGATAAG 1 chr12:116823768-11682384 ( 53) GCGATAAG 1 chr17:46624482-46624562 ( 67) CAGATTAG 1 chr18:1464602-1464682 ( 51) CAGATTAG 1 chr13:109421965-10942204 ( 57) CAGATTAG 1 chr9:251546-251626 ( 43) GTGATAAC 1 chr21:31014416-31014496 ( 60) TCGATAAG 1 chr6:135642624-135642704 ( 54) CAGATAAT 1 chr1:246741200-246741280 ( 58) CAGATAAT 1 chr8:8869654-8869734 ( 18) TTGATAAC 1 chr7:91184359-91184439 ( 37) TTGATAAA 1 chr8:130468563-130468643 ( 31) TAGATTAG 1 chr5:149319759-149319839 ( 17) GAGATAAT 1 chr5:81054736-81054816 ( 58) CTGATTAG 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif BAGATAAG MEME-1 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 8.71923 E= 1.1e-038 -85 70 12 -26 143 -202 -1310 -26 -1310 -1310 212 -1310 191 -1310 -1310 -1310 -1310 -1310 -1310 188 182 -1310 -1310 -226 191 -1310 -1310 -1310 -64 -54 146 -300 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif BAGATAAG MEME-1 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 88 E= 1.1e-038 0.147727 0.375000 0.250000 0.227273 0.715909 0.056818 0.000000 0.227273 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.943182 0.000000 0.000000 0.056818 1.000000 0.000000 0.000000 0.000000 0.170455 0.159091 0.636364 0.034091 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif BAGATAAG MEME-1 regular expression -------------------------------------------------------------------------------- [CGT][AT]GATAAG -------------------------------------------------------------------------------- Time 4.95 secs. ******************************************************************************** ******************************************************************************** MOTIF WCTTATCW MEME-2 width = 8 sites = 71 llr = 528 E-value = 1.2e-014 ******************************************************************************** -------------------------------------------------------------------------------- Motif WCTTATCW MEME-2 Description -------------------------------------------------------------------------------- Simplified A 2:::9::4 pos.-specific C 25::1:a: probability G 22:::::: matrix T 43aa:a:6 bits 2.1 * 1.9 ** ** 1.7 ** ** 1.5 ***** Relative 1.3 ***** Entropy 1.1 ***** (10.7 bits) 0.8 ****** 0.6 ******* 0.4 ******* 0.2 ******* 0.0 -------- Multilevel TCTTATCT consensus AT A sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif WCTTATCW MEME-2 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr6:14951039-14951119 45 2.11e-05 acggccctaa tcttatct gactggtgtc chr20:39890785-39890865 18 2.11e-05 tgttctcacc tcttatct ggacaactgc chr12:7446436-7446516 49 2.11e-05 gatagacagc tcttatct gacaagagca chr4:127656674-127656754 9 2.11e-05 CACTGGTG TCTTATCT CACAGACCAG chr9:97041199-97041279 46 2.11e-05 GCGTGACTCA TCTTATCT GGAGTTTTCT chr7:135930234-135930314 4 2.11e-05 CTA TCTTATCT CTGATTACTC chr7:2062732-2062812 10 4.18e-05 tcaacaccc tcttatca gaaacggaca chr5:89954561-89954641 9 4.18e-05 AATACCTT TCTTATCA ACCTTCTTGG chr7:91184359-91184439 4 4.18e-05 GCA TCTTATCA GCACGAAACA chr1:100813069-100813149 15 4.18e-05 TAGGCTAAGG TCTTATCA TTTGCGGGCA chr8:125019794-125019874 46 4.18e-05 GTTAACTGCC TCTTATCA GCATGCTCAC chr6:25910641-25910721 40 4.18e-05 TCATCATTGT TCTTATCA CCCGTGGCAA chr1:51895756-51895836 67 9.84e-05 CCCTGACTCT GCTTATCT TAGGAA chr1:182308177-182308257 14 9.84e-05 TCATCATTCT GCTTATCT CCCTCAGAGC chr6:125628625-125628705 29 9.84e-05 GTTTGACTCT GCTTATCT ACATGCATCA chr12:89934483-89934563 12 9.84e-05 gaagggtggg acttatct ctctcttccc chr4:123670886-123670966 36 9.84e-05 TTCGAGGAAA CCTTATCT ATAAGCAGTT chr16:11707753-11707833 5 9.84e-05 attt ccttatct ctaaaacgga chr22:21132189-21132269 18 9.84e-05 TGTGCTAAAA GCTTATCT TGTTTACTTA chr2:43154785-43154865 6 9.84e-05 TCGTC CCTTATCT GGGGCTCCTG chr11:91638659-91638739 27 9.84e-05 GAAGTATCTC ACTTATCT CCATCTGCCA chr8:2591456-2591536 7 1.79e-04 ttttcc gcttatca gcgtgcatct chr11:38560557-38560637 35 1.79e-04 aaggtcgtgt gcttatca catctatctg chr9:100700552-100700632 9 1.79e-04 CCTAAAAG TTTTATCT GGTTGGACCA chr2:97560979-97561059 29 1.79e-04 aacgagactt ccttatca tcatccaaca chr1:61636434-61636514 27 1.79e-04 ACGGCTGGAC ACTTATCA CAAAGCTGTG chr6:126433556-126433636 25 1.79e-04 TTGAATGCTG TTTTATCT CAAAAGGCAG chr12:9917530-9917610 8 1.79e-04 ACTCTGT GCTTATCA GACAGCTGCA chr16:9692097-9692177 22 1.79e-04 GAAACCATTT GCTTATCA TGTTTCTCCT chr2:38871039-38871119 5 1.79e-04 TCTC TTTTATCT CAACACAACA chr5:78067255-78067335 19 1.79e-04 atatttaacc ttttatct gtagcttagc chr12:23875689-23875769 63 1.79e-04 AAAGCTTCCC ACTTATCA GTCACTCAAA chrX:151345708-151345788 37 1.79e-04 gggcagaatg ttttatct tcccatgaac chr22:22302158-22302238 24 1.79e-04 AGAGGGCTGT CCTTATCA GGAATTGCTA chr7:8802534-8802614 36 1.79e-04 tcactacttt ccttatca ctgcagtcca chr5:43772956-43773036 61 1.79e-04 GAACAAGTTT TTTTATCT TTTCATGAAT chr13:30030768-30030848 31 1.79e-04 tgacagttgg ccttatca gaaatgaaca chr8:94564279-94564359 36 1.79e-04 TGAAAACTTC CCTTATCA GGCATTTCTG chr11:86642692-86642772 33 1.79e-04 aactgtcaaa acttatca aagcaaaaca chr11:46638864-46638944 63 1.79e-04 TCCGTCTTTG TTTTATCT TGAGTAGCTT chr12:63304476-63304556 57 2.00e-04 CATTAACAAC TGTTATCT CCCTCTAGCA chr4:80928215-80928295 19 2.00e-04 TTGTCTCTAC TGTTATCT GAGTTAATTC chr15:57614465-57614545 25 2.00e-04 AACGGTTCTG TGTTATCT CCCTCTCACC chr7:120681987-120682067 4 2.45e-04 TCG TGTTATCA GCAGCTTTGC chr12:94151885-94151965 26 2.45e-04 TCATTGCTGC TGTTATCA TGGTTGGATT chr22:18156026-18156106 24 3.11e-04 TAAATGCTCT ATTTATCT TCCTATCTAT chr8:130570161-130570241 44 3.11e-04 gagataagtt ctttatct gaagcaccag chr6:41293349-41293429 60 3.11e-04 TCTGTTTCCC CTTTATCT CTGGACAAAC chr3:171146193-171146273 27 3.11e-04 aggGTCATAG CTTTATCT CTCCCCCACC chr10:17038367-17038447 23 3.11e-04 GAAGTGCTTG CTTTATCT GCAGGAAGCA chrX:11606329-11606409 16 3.11e-04 AGTAATACAG GTTTATCT TATTGActta chr6:134636498-134636578 22 3.68e-04 GCTGCCTGCC AGTTATCT TGGTAGAAAC chr12:92751826-92751906 26 3.68e-04 AAGGAGGGGA GGTTATCT TTTCCTGAGG chr3:170496595-170496675 29 3.68e-04 atagagatat agttatct aaaagtctgg chr6:10402006-10402086 53 3.68e-04 TTCCGGTGGC AGTTATCT AGAGCAGGGA chr22:26122325-26122405 39 3.68e-04 GTAAGATAAG AGTTATCT TGTATGATTT chr8:102210813-102210893 2 3.68e-04 C AGTTATCT ACAGGGTACA chr14:68103314-68103394 72 4.33e-04 GCCTGGAGAG GTTTATCA A chr12:56520681-56520761 54 4.33e-04 ACCAGATAAA ATTTATCA GCTGCAGGCC chr2:138777007-138777087 46 4.33e-04 GCCTTAGCTT ATTTATCA AGATATTGCT chr12:102823621-10282370 70 4.33e-04 TCATTTTCCA ATTTATCA CAG chr1:207483425-207483505 69 4.33e-04 TCTGGATAAG ATTTATCA AAAT chr6:134279197-134279277 12 4.88e-04 ACAGGCATCT GGTTATCA CTGATGGCAG chr6:119460527-119460607 7 4.88e-04 GTTTCT GGTTATCA CACTTAACTC chr20:51797654-51797734 58 5.07e-04 ataaagaatc tcttctct acatcccttt chr8:130468563-130468643 10 5.07e-04 tctgagaag tcttctct gacactctca chr6:138225787-138225867 7 5.25e-04 CACAGG TCTTCTCA TTGCATGCCT chr4:159963510-159963590 7 5.74e-04 TGGAGC ACTTCTCT ACATTGGCCG chr11:16359521-16359601 2 5.74e-04 A CCTTCTCT GACAGAAAAC chr7:112782514-112782594 13 7.25e-04 ctaaaatact tattatct ctccttgagc chr6:26332175-26332255 57 8.77e-04 TTGTGCTGCA TCTTTTCT GAGAGATAAC -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif WCTTATCW MEME-2 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr6:14951039-14951119 2.1e-05 44_[+2]_28 chr20:39890785-39890865 2.1e-05 17_[+2]_55 chr12:7446436-7446516 2.1e-05 48_[+2]_24 chr4:127656674-127656754 2.1e-05 8_[+2]_64 chr9:97041199-97041279 2.1e-05 45_[+2]_27 chr7:135930234-135930314 2.1e-05 3_[+2]_69 chr7:2062732-2062812 4.2e-05 9_[+2]_63 chr5:89954561-89954641 4.2e-05 8_[+2]_64 chr7:91184359-91184439 4.2e-05 3_[+2]_69 chr1:100813069-100813149 4.2e-05 14_[+2]_58 chr8:125019794-125019874 4.2e-05 45_[+2]_27 chr6:25910641-25910721 4.2e-05 39_[+2]_33 chr1:51895756-51895836 9.8e-05 66_[+2]_6 chr1:182308177-182308257 9.8e-05 13_[+2]_59 chr6:125628625-125628705 9.8e-05 28_[+2]_44 chr12:89934483-89934563 9.8e-05 11_[+2]_61 chr4:123670886-123670966 9.8e-05 35_[+2]_37 chr16:11707753-11707833 9.8e-05 4_[+2]_68 chr22:21132189-21132269 9.8e-05 17_[+2]_55 chr2:43154785-43154865 9.8e-05 5_[+2]_67 chr11:91638659-91638739 9.8e-05 26_[+2]_46 chr8:2591456-2591536 0.00018 6_[+2]_66 chr11:38560557-38560637 0.00018 34_[+2]_38 chr9:100700552-100700632 0.00018 8_[+2]_64 chr2:97560979-97561059 0.00018 28_[+2]_44 chr1:61636434-61636514 0.00018 26_[+2]_46 chr6:126433556-126433636 0.00018 24_[+2]_48 chr12:9917530-9917610 0.00018 7_[+2]_65 chr16:9692097-9692177 0.00018 21_[+2]_51 chr2:38871039-38871119 0.00018 4_[+2]_68 chr5:78067255-78067335 0.00018 18_[+2]_54 chr12:23875689-23875769 0.00018 62_[+2]_10 chrX:151345708-151345788 0.00018 36_[+2]_36 chr22:22302158-22302238 0.00018 23_[+2]_49 chr7:8802534-8802614 0.00018 35_[+2]_37 chr5:43772956-43773036 0.00018 60_[+2]_12 chr13:30030768-30030848 0.00018 30_[+2]_42 chr8:94564279-94564359 0.00018 35_[+2]_37 chr11:86642692-86642772 0.00018 32_[+2]_40 chr11:46638864-46638944 0.00018 62_[+2]_10 chr12:63304476-63304556 0.0002 56_[+2]_16 chr4:80928215-80928295 0.0002 18_[+2]_54 chr15:57614465-57614545 0.0002 24_[+2]_48 chr7:120681987-120682067 0.00024 3_[+2]_69 chr12:94151885-94151965 0.00024 25_[+2]_47 chr22:18156026-18156106 0.00031 23_[+2]_49 chr8:130570161-130570241 0.00031 43_[+2]_29 chr6:41293349-41293429 0.00031 59_[+2]_13 chr3:171146193-171146273 0.00031 26_[+2]_46 chr10:17038367-17038447 0.00031 22_[+2]_50 chrX:11606329-11606409 0.00031 15_[+2]_57 chr6:134636498-134636578 0.00037 21_[+2]_51 chr12:92751826-92751906 0.00037 25_[+2]_47 chr3:170496595-170496675 0.00037 28_[+2]_44 chr6:10402006-10402086 0.00037 52_[+2]_20 chr22:26122325-26122405 0.00037 38_[+2]_34 chr8:102210813-102210893 0.00037 1_[+2]_71 chr14:68103314-68103394 0.00043 71_[+2]_1 chr12:56520681-56520761 0.00043 53_[+2]_19 chr2:138777007-138777087 0.00043 45_[+2]_27 chr12:102823621-10282370 0.00043 69_[+2]_3 chr1:207483425-207483505 0.00043 68_[+2]_4 chr6:134279197-134279277 0.00049 11_[+2]_61 chr6:119460527-119460607 0.00049 6_[+2]_66 chr20:51797654-51797734 0.00051 57_[+2]_15 chr8:130468563-130468643 0.00051 9_[+2]_63 chr6:138225787-138225867 0.00052 6_[+2]_66 chr4:159963510-159963590 0.00057 6_[+2]_66 chr11:16359521-16359601 0.00057 1_[+2]_71 chr7:112782514-112782594 0.00073 12_[+2]_60 chr6:26332175-26332255 0.00088 56_[+2]_16 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif WCTTATCW MEME-2 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF WCTTATCW width=8 seqs=71 chr6:14951039-14951119 ( 45) TCTTATCT 1 chr20:39890785-39890865 ( 18) TCTTATCT 1 chr12:7446436-7446516 ( 49) TCTTATCT 1 chr4:127656674-127656754 ( 9) TCTTATCT 1 chr9:97041199-97041279 ( 46) TCTTATCT 1 chr7:135930234-135930314 ( 4) TCTTATCT 1 chr7:2062732-2062812 ( 10) TCTTATCA 1 chr5:89954561-89954641 ( 9) TCTTATCA 1 chr7:91184359-91184439 ( 4) TCTTATCA 1 chr1:100813069-100813149 ( 15) TCTTATCA 1 chr8:125019794-125019874 ( 46) TCTTATCA 1 chr6:25910641-25910721 ( 40) TCTTATCA 1 chr1:51895756-51895836 ( 67) GCTTATCT 1 chr1:182308177-182308257 ( 14) GCTTATCT 1 chr6:125628625-125628705 ( 29) GCTTATCT 1 chr12:89934483-89934563 ( 12) ACTTATCT 1 chr4:123670886-123670966 ( 36) CCTTATCT 1 chr16:11707753-11707833 ( 5) CCTTATCT 1 chr22:21132189-21132269 ( 18) GCTTATCT 1 chr2:43154785-43154865 ( 6) CCTTATCT 1 chr11:91638659-91638739 ( 27) ACTTATCT 1 chr8:2591456-2591536 ( 7) GCTTATCA 1 chr11:38560557-38560637 ( 35) GCTTATCA 1 chr9:100700552-100700632 ( 9) TTTTATCT 1 chr2:97560979-97561059 ( 29) CCTTATCA 1 chr1:61636434-61636514 ( 27) ACTTATCA 1 chr6:126433556-126433636 ( 25) TTTTATCT 1 chr12:9917530-9917610 ( 8) GCTTATCA 1 chr16:9692097-9692177 ( 22) GCTTATCA 1 chr2:38871039-38871119 ( 5) TTTTATCT 1 chr5:78067255-78067335 ( 19) TTTTATCT 1 chr12:23875689-23875769 ( 63) ACTTATCA 1 chrX:151345708-151345788 ( 37) TTTTATCT 1 chr22:22302158-22302238 ( 24) CCTTATCA 1 chr7:8802534-8802614 ( 36) CCTTATCA 1 chr5:43772956-43773036 ( 61) TTTTATCT 1 chr13:30030768-30030848 ( 31) CCTTATCA 1 chr8:94564279-94564359 ( 36) CCTTATCA 1 chr11:86642692-86642772 ( 33) ACTTATCA 1 chr11:46638864-46638944 ( 63) TTTTATCT 1 chr12:63304476-63304556 ( 57) TGTTATCT 1 chr4:80928215-80928295 ( 19) TGTTATCT 1 chr15:57614465-57614545 ( 25) TGTTATCT 1 chr7:120681987-120682067 ( 4) TGTTATCA 1 chr12:94151885-94151965 ( 26) TGTTATCA 1 chr22:18156026-18156106 ( 24) ATTTATCT 1 chr8:130570161-130570241 ( 44) CTTTATCT 1 chr6:41293349-41293429 ( 60) CTTTATCT 1 chr3:171146193-171146273 ( 27) CTTTATCT 1 chr10:17038367-17038447 ( 23) CTTTATCT 1 chrX:11606329-11606409 ( 16) GTTTATCT 1 chr6:134636498-134636578 ( 22) AGTTATCT 1 chr12:92751826-92751906 ( 26) GGTTATCT 1 chr3:170496595-170496675 ( 29) AGTTATCT 1 chr6:10402006-10402086 ( 53) AGTTATCT 1 chr22:26122325-26122405 ( 39) AGTTATCT 1 chr8:102210813-102210893 ( 2) AGTTATCT 1 chr14:68103314-68103394 ( 72) GTTTATCA 1 chr12:56520681-56520761 ( 54) ATTTATCA 1 chr2:138777007-138777087 ( 46) ATTTATCA 1 chr12:102823621-10282370 ( 70) ATTTATCA 1 chr1:207483425-207483505 ( 69) ATTTATCA 1 chr6:134279197-134279277 ( 12) GGTTATCA 1 chr6:119460527-119460607 ( 7) GGTTATCA 1 chr20:51797654-51797734 ( 58) TCTTCTCT 1 chr8:130468563-130468643 ( 10) TCTTCTCT 1 chr6:138225787-138225867 ( 7) TCTTCTCA 1 chr4:159963510-159963590 ( 7) ACTTCTCT 1 chr11:16359521-16359601 ( 2) CCTTCTCT 1 chr7:112782514-112782594 ( 13) TATTATCT 1 chr6:26332175-26332255 ( 57) TCTTTTCT 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif WCTTATCW MEME-2 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 8.11921 E= 1.2e-014 -24 -33 -33 58 -424 125 -33 -10 -1279 -1279 -1279 188 -1279 -1279 -1279 188 178 -171 -1279 -427 -1279 -1279 -1279 188 -1279 212 -1279 -1279 57 -1279 -1279 115 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif WCTTATCW MEME-2 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 71 E= 1.2e-014 0.225352 0.183099 0.183099 0.408451 0.014085 0.549296 0.183099 0.253521 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.915493 0.070423 0.000000 0.014085 0.000000 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 0.394366 0.000000 0.000000 0.605634 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif WCTTATCW MEME-2 regular expression -------------------------------------------------------------------------------- [TA][CT]TTATC[TA] -------------------------------------------------------------------------------- Time 8.61 secs. ******************************************************************************** ******************************************************************************** MOTIF TGATGCAA MEME-3 width = 8 sites = 23 llr = 222 E-value = 2.1e-007 ******************************************************************************** -------------------------------------------------------------------------------- Motif TGATGCAA MEME-3 Description -------------------------------------------------------------------------------- Simplified A ::7::1aa pos.-specific C :::::9:: probability G :a1:a::: matrix T a:2a:::: bits 2.1 * * 1.9 ** * ** 1.7 ** ** ** 1.5 ** ***** Relative 1.3 ** ***** Entropy 1.1 ** ***** (13.9 bits) 0.8 ******** 0.6 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel TGATGCAA consensus sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGATGCAA MEME-3 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr22:18156026-18156106 68 1.72e-05 CATATTTGCC TGATGCAA TATGA chr20:352622-352702 2 1.72e-05 C TGATGCAA CTGGCTGAGT chr8:129440525-129440605 18 1.72e-05 TCTGATTTTC TGATGCAA GAAGCTGCAA chr22:22139121-22139201 41 1.72e-05 tggagtgcaa tgatgcaa tcacagctaa chr11:46264886-46264966 43 1.72e-05 GCTTGCTGTC TGATGCAA CAGTTTGCAA chr20:49650409-49650489 10 1.72e-05 ttgaggaag tgatgcaa gtagcagtaa chr19:50427731-50427811 7 1.72e-05 CAGGGC TGATGCAA CCTGCCTGCA chr6:25910641-25910721 59 1.72e-05 CCGTGGCAAC TGATGCAA TTGGAAGCAA chr9:119157779-119157859 1 1.72e-05 . TGATGCAA TGAGGTGAAA chr3:119357855-119357935 2 1.72e-05 G TGATGCAA TCATGTGACA chr19:42514615-42514695 46 1.72e-05 agcccaaaga tgatgcaa catgctgaaa chr4:151237579-151237659 26 1.72e-05 AGGAACTACC TGATGCAA CCTTGTGCAA chr2:209794283-209794363 35 1.72e-05 catgagcagc tgatgcaa gaggaaataa chr1:221881521-221881601 61 3.47e-05 GAGACGGTTA TGTTGCAA TAAGGACAGG chr10:104748879-10474895 64 3.47e-05 AGCAAACTAC TGTTGCAA AAACCCTGG chr2:38871039-38871119 57 3.47e-05 TTAGAGGGAA TGTTGCAA CAATAATGAA chr19:823845-823925 26 3.47e-05 GGAATCTGGG TGTTGCAA GGTGACCACA chr12:56520681-56520761 21 6.94e-05 AAACACAGGC TGATGAAA TCTATGCCCT chr20:52534057-52534137 23 6.94e-05 CAGAAAGAAA TGATGAAA AACAGTACAG chr2:106217573-106217653 47 6.94e-05 tagttacggc tggtgcaa caggggtcag chr11:59735639-59735719 57 6.94e-05 CATGGTTACA TGGTGCAA TTGTGGTCCA chr10:21386603-21386683 44 6.94e-05 GGTCAATTTC TGATGAAA CTGGAATGCA chr5:149319759-149319839 62 8.40e-05 gggaaacgag tGAGGCAA TCCTTGTTGG -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGATGCAA MEME-3 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr22:18156026-18156106 1.7e-05 67_[+3]_5 chr20:352622-352702 1.7e-05 1_[+3]_71 chr8:129440525-129440605 1.7e-05 17_[+3]_55 chr22:22139121-22139201 1.7e-05 40_[+3]_32 chr11:46264886-46264966 1.7e-05 42_[+3]_30 chr20:49650409-49650489 1.7e-05 9_[+3]_63 chr19:50427731-50427811 1.7e-05 6_[+3]_66 chr6:25910641-25910721 1.7e-05 58_[+3]_14 chr9:119157779-119157859 1.7e-05 [+3]_72 chr3:119357855-119357935 1.7e-05 1_[+3]_71 chr19:42514615-42514695 1.7e-05 45_[+3]_27 chr4:151237579-151237659 1.7e-05 25_[+3]_47 chr2:209794283-209794363 1.7e-05 34_[+3]_38 chr1:221881521-221881601 3.5e-05 60_[+3]_12 chr10:104748879-10474895 3.5e-05 63_[+3]_9 chr2:38871039-38871119 3.5e-05 56_[+3]_16 chr19:823845-823925 3.5e-05 25_[+3]_47 chr12:56520681-56520761 6.9e-05 20_[+3]_52 chr20:52534057-52534137 6.9e-05 22_[+3]_50 chr2:106217573-106217653 6.9e-05 46_[+3]_26 chr11:59735639-59735719 6.9e-05 56_[+3]_16 chr10:21386603-21386683 6.9e-05 43_[+3]_29 chr5:149319759-149319839 8.4e-05 61_[+3]_11 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGATGCAA MEME-3 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF TGATGCAA width=8 seqs=23 chr22:18156026-18156106 ( 68) TGATGCAA 1 chr20:352622-352702 ( 2) TGATGCAA 1 chr8:129440525-129440605 ( 18) TGATGCAA 1 chr22:22139121-22139201 ( 41) TGATGCAA 1 chr11:46264886-46264966 ( 43) TGATGCAA 1 chr20:49650409-49650489 ( 10) TGATGCAA 1 chr19:50427731-50427811 ( 7) TGATGCAA 1 chr6:25910641-25910721 ( 59) TGATGCAA 1 chr9:119157779-119157859 ( 1) TGATGCAA 1 chr3:119357855-119357935 ( 2) TGATGCAA 1 chr19:42514615-42514695 ( 46) TGATGCAA 1 chr4:151237579-151237659 ( 26) TGATGCAA 1 chr2:209794283-209794363 ( 35) TGATGCAA 1 chr1:221881521-221881601 ( 61) TGTTGCAA 1 chr10:104748879-10474895 ( 64) TGTTGCAA 1 chr2:38871039-38871119 ( 57) TGTTGCAA 1 chr19:823845-823925 ( 26) TGTTGCAA 1 chr12:56520681-56520761 ( 21) TGATGAAA 1 chr20:52534057-52534137 ( 23) TGATGAAA 1 chr2:106217573-106217653 ( 47) TGGTGCAA 1 chr11:59735639-59735719 ( 57) TGGTGCAA 1 chr10:21386603-21386683 ( 44) TGATGAAA 1 chr5:149319759-149319839 ( 62) TGAGGCAA 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGATGCAA MEME-3 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 10.0332 E= 2.1e-007 -1117 -1117 -1117 188 -1117 -1117 212 -1117 147 -1117 -141 -65 -1117 -1117 -240 181 -1117 -1117 212 -1117 -103 191 -1117 -1117 191 -1117 -1117 -1117 191 -1117 -1117 -1117 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGATGCAA MEME-3 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 23 E= 2.1e-007 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.739130 0.000000 0.086957 0.173913 0.000000 0.000000 0.043478 0.956522 0.000000 0.000000 1.000000 0.000000 0.130435 0.869565 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGATGCAA MEME-3 regular expression -------------------------------------------------------------------------------- TGATGCAA -------------------------------------------------------------------------------- Time 12.14 secs. ******************************************************************************** ******************************************************************************** MOTIF TTKCATCA MEME-4 width = 8 sites = 21 llr = 209 E-value = 2.0e-007 ******************************************************************************** -------------------------------------------------------------------------------- Motif TTKCATCA MEME-4 Description -------------------------------------------------------------------------------- Simplified A ::1:a::a pos.-specific C :::a::a: probability G ::5::::: matrix T aa4::a:: bits 2.1 * * 1.9 ** ***** 1.7 ** ***** 1.5 ** ***** Relative 1.3 ** ***** Entropy 1.1 ** ***** (14.3 bits) 0.8 ** ***** 0.6 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel TTGCATCA consensus T sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTKCATCA MEME-4 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr3:127729207-127729287 59 1.76e-05 ttcaggatca ttgcatca tgttggttgc chr14:68103314-68103394 14 1.76e-05 TACAGCCTGG TTGCATCA TTCTGTTGAT chr9:101630140-101630220 22 1.76e-05 TTTCCTCCCA TTGCATCA TCCTTCCTCA chr6:138225787-138225867 50 1.76e-05 ATTGAAACTA TTGCATCA CCTTGCTGCA chr11:78001417-78001497 57 1.76e-05 GACCTGGAAG TTGCATCA CTCCTAGCTG chr16:56015641-56015721 31 1.76e-05 atttctctga ttgcatca tcgtgattag chr17:900265-900345 22 1.76e-05 GAATCTGCCG TTGCATCA CAGTGGCTAG chr18:967175-967255 35 1.76e-05 CACTGCCAGA TTGCATCA AACCGTTTTA chrX:1600783-1600863 39 1.76e-05 TTTTCCTGTA TTGCATCA CCCAACGAAG chr2:197264976-197265056 27 1.76e-05 TGCAAAGAAA TTGCATCA CTCCTGTTAC chr9:128005735-128005815 14 1.76e-05 ACTACAGAGG TTGCATCA TGCATCTCTT chr1:182308177-182308257 2 3.82e-05 G TTTCATCA TTCTGCTTAT chr2:55343355-55343435 21 3.82e-05 TTTCTAATTG TTTCATCA GGCTGATCCT chr11:73495515-73495595 38 3.82e-05 TTGCAGCCTC TTTCATCA TCTTTTCGCC chr11:3941484-3941564 66 3.82e-05 ttcagaacat tttcatca ccctaaa chr12:121581778-12158185 18 3.82e-05 tttcagaaca tttcatca gcccagtaag chr1:12805381-12805461 22 3.82e-05 Ttgcagagga tttcatca tctggatgta chr20:382720-382800 24 3.82e-05 ttgcatgaga tttcatca tgtggttggc chr11:91638659-91638739 70 3.82e-05 CAGTTATGGA TTTCATCA TCT chr5:171381081-171381161 58 5.84e-05 TGCCAGTCTA TTACATCA TGCTGCTGTG chr5:43772956-43773036 25 5.84e-05 TACACGGGTA TTACATCA GTCAGGAAAT -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTKCATCA MEME-4 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr3:127729207-127729287 1.8e-05 58_[+4]_14 chr14:68103314-68103394 1.8e-05 13_[+4]_59 chr9:101630140-101630220 1.8e-05 21_[+4]_51 chr6:138225787-138225867 1.8e-05 49_[+4]_23 chr11:78001417-78001497 1.8e-05 56_[+4]_16 chr16:56015641-56015721 1.8e-05 30_[+4]_42 chr17:900265-900345 1.8e-05 21_[+4]_51 chr18:967175-967255 1.8e-05 34_[+4]_38 chrX:1600783-1600863 1.8e-05 38_[+4]_34 chr2:197264976-197265056 1.8e-05 26_[+4]_46 chr9:128005735-128005815 1.8e-05 13_[+4]_59 chr1:182308177-182308257 3.8e-05 1_[+4]_71 chr2:55343355-55343435 3.8e-05 20_[+4]_52 chr11:73495515-73495595 3.8e-05 37_[+4]_35 chr11:3941484-3941564 3.8e-05 65_[+4]_7 chr12:121581778-12158185 3.8e-05 17_[+4]_55 chr1:12805381-12805461 3.8e-05 21_[+4]_51 chr20:382720-382800 3.8e-05 23_[+4]_49 chr11:91638659-91638739 3.8e-05 69_[+4]_3 chr5:171381081-171381161 5.8e-05 57_[+4]_15 chr5:43772956-43773036 5.8e-05 24_[+4]_48 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTKCATCA MEME-4 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF TTKCATCA width=8 seqs=21 chr3:127729207-127729287 ( 59) TTGCATCA 1 chr14:68103314-68103394 ( 14) TTGCATCA 1 chr9:101630140-101630220 ( 22) TTGCATCA 1 chr6:138225787-138225867 ( 50) TTGCATCA 1 chr11:78001417-78001497 ( 57) TTGCATCA 1 chr16:56015641-56015721 ( 31) TTGCATCA 1 chr17:900265-900345 ( 22) TTGCATCA 1 chr18:967175-967255 ( 35) TTGCATCA 1 chrX:1600783-1600863 ( 39) TTGCATCA 1 chr2:197264976-197265056 ( 27) TTGCATCA 1 chr9:128005735-128005815 ( 14) TTGCATCA 1 chr1:182308177-182308257 ( 2) TTTCATCA 1 chr2:55343355-55343435 ( 21) TTTCATCA 1 chr11:73495515-73495595 ( 38) TTTCATCA 1 chr11:3941484-3941564 ( 66) TTTCATCA 1 chr12:121581778-12158185 ( 18) TTTCATCA 1 chr1:12805381-12805461 ( 22) TTTCATCA 1 chr20:382720-382800 ( 24) TTTCATCA 1 chr11:91638659-91638739 ( 70) TTTCATCA 1 chr5:171381081-171381161 ( 58) TTACATCA 1 chr5:43772956-43773036 ( 25) TTACATCA 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTKCATCA MEME-4 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 10.0668 E= 2.0e-007 -1104 -1104 -1104 188 -1104 -1104 -1104 188 -148 -1104 118 48 -1104 212 -1104 -1104 191 -1104 -1104 -1104 -1104 -1104 -1104 188 -1104 212 -1104 -1104 191 -1104 -1104 -1104 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTKCATCA MEME-4 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 21 E= 2.0e-007 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.095238 0.000000 0.523810 0.380952 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTKCATCA MEME-4 regular expression -------------------------------------------------------------------------------- TT[GT]CATCA -------------------------------------------------------------------------------- Time 15.62 secs. ******************************************************************************** ******************************************************************************** MOTIF RCTKCCTG MEME-5 width = 8 sites = 34 llr = 294 E-value = 2.6e-006 ******************************************************************************** -------------------------------------------------------------------------------- Motif RCTKCCTG MEME-5 Description -------------------------------------------------------------------------------- Simplified A 3:::::3: pos.-specific C 2a::aa:: probability G 4::4:::a matrix T 2:a6::7: bits 2.1 * ** * 1.9 ** ** * 1.7 ** ** * 1.5 ** ** * Relative 1.3 ** ** * Entropy 1.1 ******* (12.5 bits) 0.8 ******* 0.6 ******* 0.4 ******* 0.2 ******* 0.0 -------- Multilevel GCTTCCTG consensus A G A sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif RCTKCCTG MEME-5 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr5:89940136-89940216 56 1.32e-05 TGAGCATGCA GCTTCCTG TAACTGCTTT chr3:171146193-171146273 48 1.32e-05 CCCCACCACT GCTTCCTG CCCCCTGTGG chr16:11707753-11707833 66 1.32e-05 GGGTCCCTCT GCTTCCTG GCAGGTC chr14:101237703-10123778 45 1.32e-05 gttggcccca gcttcctg tccttggaga chr11:34831305-34831385 23 1.32e-05 taacaggctg gcttcctg aactgtttat chr16:79897801-79897881 47 1.32e-05 AGTAGCAGAA GCTTCCTG TGGTAGGAAA chr6:134636498-134636578 12 2.45e-05 GTTAGATGAA GCTGCCTG CCAGTTATCT chr10:52086765-52086845 49 2.45e-05 GAAGGGTGGG GCTGCCTG GCCATATCAT chr7:135930234-135930314 25 2.45e-05 ATTACTCTCT GCTGCCTG GCCTTCTGAT chr22:47000433-47000513 51 3.97e-05 ctcccaatcc acttcctg tctctgtgca chr4:81048660-81048740 35 3.97e-05 CACACTTTAA ACTTCCTG ACAGTTAGTG chr21:31021826-31021906 7 3.97e-05 TATCAC ACTTCCTG CCCAGGGGAT chr1:40525261-40525341 68 3.97e-05 TAACACAAGA ACTTCCTG CTTGT chr12:11951932-11952012 57 3.97e-05 GATCTTGGGA ACTTCCTG TGGAGGAGTG chr19:45596216-45596296 39 6.59e-05 TTTCCGTGGC CCTTCCTG CCCTTTGTTT chr11:16359521-16359601 53 6.59e-05 AAAGTAAAAC CCTTCCTG TACCCAAGAG chr12:47754637-47754717 43 6.59e-05 AGGGGAGGTT CCTTCCTG GAGATGTTTT chr16:11196067-11196147 62 7.88e-05 TAAATCACAT GCTTCCAG AATGTTGCTC chr12:104531971-10453205 41 7.88e-05 GCGGAGCTCC GCTTCCAG GACTCGGCCT chrX:15534176-15534256 39 9.44e-05 CGTCTTGTTT TCTTCCTG TCTGCTCCTC chr6:45404704-45404784 11 9.44e-05 CACGCCCACC TCTTCCTG TCTTGTAACA chr19:29096656-29096736 56 9.44e-05 TCCGAAGTTA TCTTCCTG TTCCGGGGAG chr18:1464602-1464682 68 9.44e-05 GCATGACTGT TCTTCCTG TTTGG chr12:63304476-63304556 32 1.06e-04 GTCACCACCT CCTGCCTG TCCCATGCAT chr19:50427731-50427811 15 1.06e-04 GCTGATGCAA CCTGCCTG CAACCACCGC chr12:7446436-7446516 17 1.17e-04 tatttgagga gctgccag atcctacagt chr9:132641526-132641606 59 1.17e-04 GTGAGCGGCA GCTGCCAG CAGAGATAAG chr15:34949831-34949911 9 1.30e-04 gttggaaa tctgcctg gtgcagctgc chrX:11385890-11385970 15 1.45e-04 AGATTGTGGG ACTTCCAG GCTTCCGCCC chr15:58472063-58472143 53 1.70e-04 CGTGTGAGTA ACTGCCAG GGAAGCAGGG chr7:8802534-8802614 71 1.70e-04 tcaatttcca actgccag ca chr6:40346042-40346122 9 1.70e-04 ACGGGATA ACTGCCAG AGCAGAAGAC chr10:119171078-11917115 25 1.97e-04 CATAATGAGT CCTGCCAG TTAGGACTGC chr11:91638659-91638739 38 2.10e-04 CTTATCTCCA TCTGCCAG TGACCTTTAT -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif RCTKCCTG MEME-5 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr5:89940136-89940216 1.3e-05 55_[+5]_17 chr3:171146193-171146273 1.3e-05 47_[+5]_25 chr16:11707753-11707833 1.3e-05 65_[+5]_7 chr14:101237703-10123778 1.3e-05 44_[+5]_28 chr11:34831305-34831385 1.3e-05 22_[+5]_50 chr16:79897801-79897881 1.3e-05 46_[+5]_26 chr6:134636498-134636578 2.4e-05 11_[+5]_61 chr10:52086765-52086845 2.4e-05 48_[+5]_24 chr7:135930234-135930314 2.4e-05 24_[+5]_48 chr22:47000433-47000513 4e-05 50_[+5]_22 chr4:81048660-81048740 4e-05 34_[+5]_38 chr21:31021826-31021906 4e-05 6_[+5]_66 chr1:40525261-40525341 4e-05 67_[+5]_5 chr12:11951932-11952012 4e-05 56_[+5]_16 chr19:45596216-45596296 6.6e-05 38_[+5]_34 chr11:16359521-16359601 6.6e-05 52_[+5]_20 chr12:47754637-47754717 6.6e-05 42_[+5]_30 chr16:11196067-11196147 7.9e-05 61_[+5]_11 chr12:104531971-10453205 7.9e-05 40_[+5]_32 chrX:15534176-15534256 9.4e-05 38_[+5]_34 chr6:45404704-45404784 9.4e-05 10_[+5]_62 chr19:29096656-29096736 9.4e-05 55_[+5]_17 chr18:1464602-1464682 9.4e-05 67_[+5]_5 chr12:63304476-63304556 0.00011 31_[+5]_41 chr19:50427731-50427811 0.00011 14_[+5]_58 chr12:7446436-7446516 0.00012 16_[+5]_56 chr9:132641526-132641606 0.00012 58_[+5]_14 chr15:34949831-34949911 0.00013 8_[+5]_64 chrX:11385890-11385970 0.00014 14_[+5]_58 chr15:58472063-58472143 0.00017 52_[+5]_20 chr7:8802534-8802614 0.00017 70_[+5]_2 chr6:40346042-40346122 0.00017 8_[+5]_64 chr10:119171078-11917115 0.0002 24_[+5]_48 chr11:91638659-91638739 0.00021 37_[+5]_35 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif RCTKCCTG MEME-5 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF RCTKCCTG width=8 seqs=34 chr5:89940136-89940216 ( 56) GCTTCCTG 1 chr3:171146193-171146273 ( 48) GCTTCCTG 1 chr16:11707753-11707833 ( 66) GCTTCCTG 1 chr14:101237703-10123778 ( 45) GCTTCCTG 1 chr11:34831305-34831385 ( 23) GCTTCCTG 1 chr16:79897801-79897881 ( 47) GCTTCCTG 1 chr6:134636498-134636578 ( 12) GCTGCCTG 1 chr10:52086765-52086845 ( 49) GCTGCCTG 1 chr7:135930234-135930314 ( 25) GCTGCCTG 1 chr22:47000433-47000513 ( 51) ACTTCCTG 1 chr4:81048660-81048740 ( 35) ACTTCCTG 1 chr21:31021826-31021906 ( 7) ACTTCCTG 1 chr1:40525261-40525341 ( 68) ACTTCCTG 1 chr12:11951932-11952012 ( 57) ACTTCCTG 1 chr19:45596216-45596296 ( 39) CCTTCCTG 1 chr11:16359521-16359601 ( 53) CCTTCCTG 1 chr12:47754637-47754717 ( 43) CCTTCCTG 1 chr16:11196067-11196147 ( 62) GCTTCCAG 1 chr12:104531971-10453205 ( 41) GCTTCCAG 1 chrX:15534176-15534256 ( 39) TCTTCCTG 1 chr6:45404704-45404784 ( 11) TCTTCCTG 1 chr19:29096656-29096736 ( 56) TCTTCCTG 1 chr18:1464602-1464682 ( 68) TCTTCCTG 1 chr12:63304476-63304556 ( 32) CCTGCCTG 1 chr19:50427731-50427811 ( 15) CCTGCCTG 1 chr12:7446436-7446516 ( 17) GCTGCCAG 1 chr9:132641526-132641606 ( 59) GCTGCCAG 1 chr15:34949831-34949911 ( 9) TCTGCCTG 1 chrX:11385890-11385970 ( 15) ACTTCCAG 1 chr15:58472063-58472143 ( 53) ACTGCCAG 1 chr7:8802534-8802614 ( 71) ACTGCCAG 1 chr6:40346042-40346122 ( 9) ACTGCCAG 1 chr10:119171078-11917115 ( 25) CCTGCCAG 1 chr11:91638659-91638739 ( 38) TCTGCCAG 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif RCTKCCTG MEME-5 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 9.13512 E= 2.6e-006 -1 -39 73 -63 -1173 212 -1173 -1173 -1173 -1173 -1173 188 -1173 -1173 73 118 -1173 212 -1173 -1173 -1173 212 -1173 -1173 14 -1173 -1173 137 -1173 -1173 212 -1173 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif RCTKCCTG MEME-5 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 34 E= 2.6e-006 0.264706 0.176471 0.382353 0.176471 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.382353 0.617647 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.294118 0.000000 0.000000 0.705882 0.000000 0.000000 1.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif RCTKCCTG MEME-5 regular expression -------------------------------------------------------------------------------- [GA]CT[TG]CC[TA]G -------------------------------------------------------------------------------- Time 19.05 secs. ******************************************************************************** ******************************************************************************** SUMMARY OF MOTIFS ******************************************************************************** -------------------------------------------------------------------------------- Combined block diagrams: non-overlapping sites with p-value < 0.0001 -------------------------------------------------------------------------------- SEQUENCE NAME COMBINED P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr3:72510086-72510166 5.92e-01 80 chr10:21386603-21386683 1.27e-02 21_[+1(8.98e-05)]_14_[+3(6.94e-05)]_\ 29 chr6:13980256-13980336 5.07e-02 80 chr9:128005735-128005815 1.42e-02 13_[+4(1.76e-05)]_59 chr1:160370184-160370264 9.95e-01 80 chr8:102210813-102210893 1.36e-01 80 chr2:209794283-209794363 3.66e-02 34_[+3(1.72e-05)]_38 chr5:159066115-159066195 2.75e-01 80 chr22:21221903-21221983 2.13e-02 62_[+1(8.98e-05)]_10 chr7:86736663-86736743 3.78e-01 80 chr12:104531971-10453205 3.11e-01 40_[+5(7.88e-05)]_32 chr3:156825712-156825792 4.87e-02 80 chr11:91638659-91638739 7.05e-04 26_[+2(9.84e-05)]_35_[+4(3.82e-05)]_\ 3 chr11:46638864-46638944 2.59e-01 80 chr6:26332175-26332255 7.13e-03 80 chr2:197264976-197265056 4.34e-03 26_[+4(1.76e-05)]_46 chr22:26122325-26122405 1.93e-03 30_[+1(8.98e-05)]_42 chr19:823845-823925 1.02e-01 25_[+3(3.47e-05)]_47 chr20:382720-382800 2.38e-02 23_[+4(3.82e-05)]_49 chr20:32319994-32320074 9.97e-01 80 chr4:151237579-151237659 1.73e-03 25_[+3(1.72e-05)]_47 chr16:69599757-69599837 9.00e-01 80 chr19:42514615-42514695 2.28e-03 45_[+3(1.72e-05)]_27 chr9:101103890-101103970 2.34e-02 80 chr5:43067060-43067140 3.88e-01 80 chrX:11606329-11606409 6.78e-02 80 chr3:151961277-151961357 5.58e-01 80 chrX:131180713-131180793 9.92e-03 56_[+1(8.98e-05)]_16 chr3:119414458-119414538 6.44e-01 80 chr7:135930234-135930314 1.68e-04 3_[+2(2.11e-05)]_13_[+5(2.45e-05)]_\ 48 chr1:117388864-117388944 7.53e-01 80 chrX:1600783-1600863 3.37e-02 38_[+4(1.76e-05)]_34 chr12:11951932-11952012 7.90e-02 56_[+5(3.97e-05)]_16 chr8:8869654-8869734 2.45e-01 80 chr12:4647695-4647775 2.37e-02 80 chr4:139694602-139694682 2.97e-03 59_[+1(3.36e-05)]_13 chr17:34901349-34901429 3.78e-01 80 chr2:43154785-43154865 5.79e-02 5_[+2(9.84e-05)]_67 chr12:94151885-94151965 8.84e-02 80 chr10:52086765-52086845 7.44e-02 48_[+5(2.45e-05)]_24 chr4:127659407-127659487 7.82e-02 80 chr22:21132189-21132269 2.03e-02 17_[+2(9.84e-05)]_55 chr16:79897801-79897881 2.77e-03 46_[+5(1.32e-05)]_12_[+2(9.84e-05)]_\ 6 chr12:116823768-11682384 7.35e-02 80 chr9:132641526-132641606 9.35e-03 68_[+1(3.36e-05)]_4 chr1:12805381-12805461 2.90e-02 21_[+4(3.82e-05)]_51 chr5:149319759-149319839 3.92e-02 61_[+3(8.40e-05)]_11 chr17:38804172-38804252 1.97e-01 80 chr1:246741200-246741280 4.71e-02 80 chr11:86642692-86642772 2.99e-01 80 chr8:41909520-41909600 3.62e-01 80 chr12:121581778-12158185 3.19e-02 17_[+4(3.82e-05)]_55 chr3:119357855-119357935 1.58e-02 1_[+3(1.72e-05)]_71 chr18:3603156-3603236 5.02e-02 80 chr8:135725183-135725263 6.04e-01 80 chr9:119157779-119157859 4.56e-02 [+3(1.72e-05)]_72 chr22:40316294-40316374 6.21e-02 80 chr2:196351889-196351969 2.00e-02 48_[+1(5.33e-05)]_24 chr13:37574762-37574842 8.33e-01 80 chr17:38673180-38673260 1.99e-01 80 chr9:114835401-114835481 6.50e-02 80 chr15:57614465-57614545 4.70e-02 80 chr16:84571383-84571463 3.86e-01 80 chr13:109421965-10942204 4.45e-01 80 chr1:207483425-207483505 3.45e-02 80 chr8:94564279-94564359 2.79e-02 80 chr12:47754637-47754717 1.19e-02 42_[+5(6.59e-05)]_30 chr11:3941484-3941564 6.44e-02 65_[+4(3.82e-05)]_7 chr18:1464602-1464682 2.38e-03 67_[+5(9.44e-05)]_5 chr6:25910641-25910721 1.17e-03 39_[+2(4.18e-05)]_11_[+3(1.72e-05)]_\ 14 chr2:231524060-231524140 2.28e-01 18_[+1(8.98e-05)]_2_[+1(8.98e-05)]_\ 44 chr6:119460527-119460607 1.53e-01 80 chr18:967175-967255 2.27e-03 34_[+4(1.76e-05)]_38 chr6:40346042-40346122 6.62e-02 80 chr17:900265-900345 9.61e-02 21_[+4(1.76e-05)]_51 chr12:102823621-10282370 4.87e-02 80 chr2:58958091-58958171 1.34e-01 80 chr5:138855128-138855208 7.89e-01 80 chr6:147483244-147483324 4.44e-01 80 chr2:198794136-198794216 3.08e-02 60_[+1(1.68e-05)]_12 chr6:10402006-10402086 1.43e-02 80 chr3:137918866-137918946 6.05e-01 80 chr9:123659625-123659705 3.73e-01 80 chr10:5504471-5504551 1.39e-01 80 chr1:40525261-40525341 3.46e-04 6_[+1(1.68e-05)]_53_[+5(3.97e-05)]_\ 5 chr9:130301902-130301982 4.54e-01 80 chr13:30030768-30030848 2.87e-01 80 chr4:56596121-56596201 5.59e-04 59_[+5(6.59e-05)]_13 chr11:34831305-34831385 8.70e-05 22_[+5(1.32e-05)]_12_[+1(1.68e-05)]_\ 30 chr5:43772956-43773036 6.29e-03 24_[+4(5.84e-05)]_48 chr10:103872257-10387233 8.65e-02 80 chrX:11385890-11385970 5.73e-02 80 chr14:101237703-10123778 2.05e-03 44_[+5(1.32e-05)]_6_[+1(3.36e-05)]_\ 14 chr4:80928215-80928295 1.17e-02 80 chr6:43894503-43894583 2.02e-01 72_[+1(8.98e-05)] chr16:56015641-56015721 3.08e-03 30_[+4(1.76e-05)]_42 chr9:97041199-97041279 4.64e-02 45_[+2(2.11e-05)]_27 chr6:82915921-82916001 9.53e-01 80 chr4:2397462-2397542 2.01e-01 80 chr17:40540729-40540809 9.87e-01 80 chr19:50427731-50427811 5.36e-03 6_[+3(1.72e-05)]_66 chr16:71526120-71526200 4.71e-01 80 chrX:65218084-65218164 9.00e-02 69_[+1(1.68e-05)]_3 chr3:99536469-99536549 3.23e-01 80 chr12:123942623-12394270 9.07e-01 80 chr21:31021826-31021906 8.93e-02 6_[+5(3.97e-05)]_66 chr11:82503022-82503102 4.61e-01 80 chr8:130468563-130468643 3.52e-02 80 chr17:53894347-53894427 8.74e-02 80 chr2:15696593-15696673 6.74e-02 46_[+1(8.98e-05)]_26 chr16:56496480-56496560 2.66e-01 80 chr11:78003375-78003455 4.55e-01 80 chr2:192701674-192701754 4.84e-02 80 chr8:125019794-125019874 2.76e-02 45_[+2(4.18e-05)]_27 chr7:120681987-120682067 6.40e-02 80 chr11:73495515-73495595 2.38e-02 37_[+4(3.82e-05)]_35 chr5:81054736-81054816 2.89e-02 80 chr16:11707753-11707833 1.39e-03 4_[+2(9.84e-05)]_53_[+5(1.32e-05)]_\ 7 chr6:14453043-14453123 3.18e-01 80 chr2:145338453-145338533 2.92e-01 80 chr2:138777007-138777087 4.31e-02 80 chr9:138842326-138842406 1.04e-01 80 chr11:78001417-78001497 2.90e-02 56_[+4(1.76e-05)]_16 chr4:129438338-129438418 3.62e-01 80 chr11:59735639-59735719 1.46e-02 56_[+3(6.94e-05)]_16 chr11:16359521-16359601 8.00e-04 52_[+5(6.59e-05)]_7_[+1(3.36e-05)]_\ 5 chr4:81048660-81048740 9.67e-02 34_[+5(3.97e-05)]_38 chr20:49650409-49650489 5.49e-02 9_[+3(1.72e-05)]_63 chr1:201536255-201536335 7.93e-02 52_[+5(6.59e-05)]_20 chr7:8802534-8802614 1.97e-02 80 chr1:15110666-15110746 1.29e-01 80 chr2:106217573-106217653 9.85e-02 46_[+3(6.94e-05)]_26 chr12:60538342-60538422 1.02e-01 43_[+1(3.36e-05)]_29 chr22:22302158-22302238 1.77e-02 80 chr11:46264886-46264966 7.21e-03 42_[+3(1.72e-05)]_30 chr8:130594504-130594584 1.61e-01 80 chr6:28534080-28534160 2.96e-01 80 chr10:119171078-11917115 1.27e-01 80 chr12:94316420-94316500 8.11e-01 80 chr20:3993447-3993527 5.25e-02 80 chr12:101801661-10180174 2.37e-01 80 chr3:65573864-65573944 2.16e-01 80 chrX:151345708-151345788 2.89e-02 80 chr2:134906777-134906857 5.53e-03 80 chr7:29833281-29833361 3.33e-01 80 chr2:55343355-55343435 1.21e-03 20_[+4(3.82e-05)]_20_[+1(8.98e-05)]_\ 24 chr9:100705723-100705803 1.22e-02 80 chr15:34946969-34947049 5.27e-01 80 chr3:128134933-128135013 2.72e-01 80 chr22:22146158-22146238 7.77e-02 80 chr12:23875689-23875769 3.18e-03 80 chr1:38989340-38989420 2.52e-02 66_[+1(5.33e-05)]_6 chr2:178130730-178130810 6.70e-01 80 chr15:58472063-58472143 1.24e-02 80 chr5:78067255-78067335 7.02e-02 80 chr6:138225787-138225867 3.57e-05 23_[+1(5.33e-05)]_18_[+4(1.76e-05)]_\ 23 chrX:129890394-129890474 1.81e-01 80 chr3:170496595-170496675 1.10e-01 80 chr6:135628024-135628104 4.42e-01 80 chr20:52534057-52534137 2.89e-02 22_[+3(6.94e-05)]_50 chr1:100813069-100813149 6.84e-02 14_[+2(4.18e-05)]_58 chr7:112782514-112782594 6.31e-02 80 chr5:171381081-171381161 3.91e-02 57_[+4(5.84e-05)]_15 chr4:127656674-127656754 2.16e-02 8_[+2(2.11e-05)]_64 chr1:90169221-90169301 7.14e-02 80 chr7:91184359-91184439 5.41e-03 3_[+2(4.18e-05)]_69 chr16:11196067-11196147 1.78e-03 30_[+1(8.98e-05)]_23_[+5(7.88e-05)]_\ 11 chr17:46624482-46624562 2.84e-01 80 chr2:38871039-38871119 1.30e-03 56_[+3(3.47e-05)]_16 chr8:91209728-91209808 3.00e-01 80 chr5:111885602-111885682 5.79e-01 80 chr10:17038367-17038447 1.24e-01 80 chrX:65229242-65229322 2.43e-02 80 chrX:40032085-40032165 5.77e-01 80 chr3:150169167-150169247 1.66e-02 52_[+1(1.68e-05)]_20 chr16:9692097-9692177 3.86e-02 80 chr4:123670886-123670966 4.00e-02 35_[+2(9.84e-05)]_37 chr12:9917530-9917610 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chr17:25929817-25929897 1.43e-01 36_[+1(8.98e-05)]_36 chr1:182308177-182308257 6.92e-03 1_[+4(3.82e-05)]_4_[+2(9.84e-05)]_\ 59 chr11:38560557-38560637 6.34e-03 9_[+1(5.33e-05)]_63 chr20:352622-352702 2.28e-03 1_[+3(1.72e-05)]_71 chr14:64746987-64747067 4.22e-01 80 chr8:130570161-130570241 6.86e-03 33_[+1(3.36e-05)]_39 chr12:7446436-7446516 3.02e-03 48_[+2(2.11e-05)]_24 chr8:2591456-2591536 7.54e-02 80 chrX:65235147-65235227 4.44e-02 80 chr14:71828204-71828284 1.81e-02 65_[+1(1.68e-05)]_7 chr6:158327673-158327753 8.79e-02 22_[+1(3.36e-05)]_50 chr6:45404704-45404784 8.45e-03 10_[+5(9.44e-05)]_62 chr22:18156026-18156106 1.01e-03 67_[+3(1.72e-05)]_5 chr1:51895756-51895836 3.42e-02 66_[+2(9.84e-05)]_6 chr19:45596216-45596296 2.60e-02 38_[+5(6.59e-05)]_34 chr20:39890785-39890865 8.87e-03 17_[+2(2.11e-05)]_55 chr6:14951039-14951119 1.02e-02 44_[+2(2.11e-05)]_28 chr11:62164298-62164378 4.22e-03 32_[+1(1.68e-05)]_40 chr20:51797654-51797734 5.27e-02 80 chr5:89940136-89940216 5.58e-03 55_[+5(1.32e-05)]_17 chr1:202045348-202045428 8.45e-02 26_[+1(8.98e-05)]_46 chr12:1413619-1413699 4.95e-01 80 chr15:34949831-34949911 8.30e-03 80 chr3:127729207-127729287 2.53e-03 58_[+4(1.76e-05)]_14 chr6:134636498-134636578 6.84e-05 11_[+5(2.45e-05)]_37_[+1(1.68e-05)]_\ 16 chrX:15534176-15534256 1.42e-04 38_[+5(9.44e-05)]_11_[+1(3.36e-05)]_\ 15 chr17:27621383-27621463 4.57e-01 80 chr6:20458733-20458813 2.81e-02 30_[+1(3.36e-05)]_42 -------------------------------------------------------------------------------- ******************************************************************************** ******************************************************************************** Stopped because requested number of motifs (5) found. ******************************************************************************** CPU: c22n08.farnam.hpc.yale.internal ********************************************************************************